# geneInfo

ensembl_gene_id: HRUBRI_0001
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: HRUBRI_0002
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initia [...]


ensembl_gene_id: HRUBRI_0003
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: HRUBRI_0029
symbol: hsdR
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: HRUBRI_0066
symbol: pilT
gene_biotype: protein_coding
description:
  Twitching motility protein PilT; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: HRUBRI_0068
symbol: ALU87301.1
gene_biotype: protein_coding
description:
  methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: HRUBRI_0074
symbol: kup
gene_biotype: protein_coding
description:
  Potassium uptake transporter protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: HRUBRI_0104
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: HRUBRI_0105
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: HRUBRI_0111
symbol: tufB
gene_biotype: protein_coding
description:
  GTPase translation elongation factor TU (EF-Tu) protein; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: HRUBRI_0113
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase SecE subunit transmembrane protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: HRUBRI_0114
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: HRUBRI_0115
symbol: rplK
gene_biotype: protein_coding
description:
  50s ribosomal subunit L11 protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: HRUBRI_0116
symbol: rplA
gene_biotype: protein_coding
description:
  50s ribosomal subunit L1 protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: HRUBRI_0117
symbol: rplJ
gene_biotype: protein_coding
description:
  50s ribosomal subunit L10 protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: HRUBRI_0118
symbol: rplL
gene_biotype: protein_coding
description:
  50s ribosomal subunit L7/L12 protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: HRUBRI_0119
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HRUBRI_0123
symbol: rpsL
gene_biotype: protein_coding
description:
  30s ribosomal subunit S12 protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: HRUBRI_0124
symbol: rpsG
gene_biotype: protein_coding
description:
  30s ribosomal subunit S7 protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: HRUBRI_0125
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G1 (EF-G1) protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/E [...]


ensembl_gene_id: HRUBRI_0127
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal subunit S10 protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: HRUBRI_0128
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal subunit L3 protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: HRUBRI_0130
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal subunit L23 protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: HRUBRI_0131
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal subunit L2 protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: HRUBRI_0132
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal subunit S19 protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: HRUBRI_0133
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal subunit L22 protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: HRUBRI_0134
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal subunit S3 protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: HRUBRI_0135
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal subunit L16 protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: HRUBRI_0136
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal subunit S17 protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: HRUBRI_0137
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal subunit L14 protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: HRUBRI_0138
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal subunit L24 protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: HRUBRI_0139
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal subunit L5 protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: HRUBRI_0140
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal subunit S14 protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: HRUBRI_0141
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal subunit S8 protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: HRUBRI_0142
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal subunit L6 protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: HRUBRI_0143
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal subunit L18 protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: HRUBRI_0144
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal subunit S5 protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: HRUBRI_0146
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal subunit L15 protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: HRUBRI_0147
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: HRUBRI_0148
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor (IF-1) protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: HRUBRI_0150
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal subunit S13 protein; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: HRUBRI_0151
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal subunit S11 protein; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: HRUBRI_0152
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal subunit S4 protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: HRUBRI_0153
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HRUBRI_0157
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange transmembrane protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: HRUBRI_0163
symbol: ALU87392.1
gene_biotype: protein_coding
description:
  Carboxymuconolactone decarboxylase family protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: HRUBRI_0166
symbol: engB
gene_biotype: protein_coding
description:
  GTP binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: HRUBRI_0173
symbol: gpsA
gene_biotype: protein_coding
description:
  NAD-dependent glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: HRUBRI_0175
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: HRUBRI_0176
symbol: grxC
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: HRUBRI_0178
symbol: gpmA
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: HRUBRI_0183
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: HRUBRI_0186
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: HRUBRI_0192
symbol: livH
gene_biotype: protein_coding
description:
  ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_0201
symbol: putA
gene_biotype: protein_coding
description:
  Bifunctional proline dehydrogenase/proline oxidase delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: HRUBRI_0202
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: HRUBRI_0203
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: HRUBRI_0209
symbol: cyaY
gene_biotype: protein_coding
description:
  Frataxin-like domain-containing protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: HRUBRI_0210
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: HRUBRI_0213
symbol: otsB
gene_biotype: protein_coding
description:
  Trehalose-6-phosphate phophatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.


ensembl_gene_id: HRUBRI_0215
symbol: otsA
gene_biotype: protein_coding
description:
  Alpha,alpha-trehalose-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.


ensembl_gene_id: HRUBRI_0218
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase protein; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: HRUBRI_0222
symbol: clsB
gene_biotype: protein_coding
description:
  Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: HRUBRI_0243
symbol: gabT
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_0252
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: HRUBRI_0255
symbol: ALU87484.1
gene_biotype: protein_coding
description:
  RND family efflux transporter MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_0256
symbol: acrB
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: HRUBRI_0262
symbol: ALU87491.1
gene_biotype: protein_coding
description:
  ABC-type maltose/maltodextrin transport system, ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_0301
symbol: ALU87530.1
gene_biotype: protein_coding
description:
  HU histone family DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: HRUBRI_0303
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: HRUBRI_0304
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division FtsL transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: HRUBRI_0305
symbol: ftsI
gene_biotype: protein_coding
description:
  Cell division FtsI protein/penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: HRUBRI_0306
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: HRUBRI_0307
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: HRUBRI_0308
symbol: mraY
gene_biotype: protein_coding
description:
  Phospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: HRUBRI_0309
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: HRUBRI_0310
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: HRUBRI_0311
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: HRUBRI_0313
symbol: ddlB
gene_biotype: protein_coding
description:
  D-alanine-D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: HRUBRI_0314
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division septal protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: HRUBRI_0315
symbol: ftsA
gene_biotype: protein_coding
description:
  Actin-like ATPase involved in cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: HRUBRI_0316
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division GTPase (FtsZ); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: HRUBRI_0317
symbol: ALU87546.1
gene_biotype: protein_coding
description:
  AhpC/TSA family peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: HRUBRI_0318
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: HRUBRI_0322
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: HRUBRI_0324
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: HRUBRI_0327
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: HRUBRI_0328
symbol: zapD
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: HRUBRI_0329
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: HRUBRI_0330
symbol: pilD
gene_biotype: protein_coding
description:
  Bifunctional leader peptidase/N-methyltransferase transmembrane protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: HRUBRI_0334
symbol: infA-2
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1 protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: HRUBRI_0344
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: HRUBRI_0346
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: HRUBRI_0347
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: HRUBRI_0349
symbol: rppH
gene_biotype: protein_coding
description:
  Dinucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: HRUBRI_0350
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: HRUBRI_0353
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle subunit SRP54 protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the indiv [...]


ensembl_gene_id: HRUBRI_0360
symbol: nrdA
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: HRUBRI_0361
symbol: nrdB
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: HRUBRI_0367
symbol: prmA
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: HRUBRI_0368
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: HRUBRI_0369
symbol: ALU87597.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: HRUBRI_0370
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: HRUBRI_0376
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: HRUBRI_0378
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: HRUBRI_0381
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: HRUBRI_0382
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: HRUBRI_0383
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transporter; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: HRUBRI_0385
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: HRUBRI_0387
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: HRUBRI_0388
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DT [...]


ensembl_gene_id: HRUBRI_0393
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: HRUBRI_0402
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: HRUBRI_0404
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: HRUBRI_0405
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: HRUBRI_0409
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: HRUBRI_0410
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: HRUBRI_0412
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: HRUBRI_0414
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: HRUBRI_0439
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: HRUBRI_0444
symbol: pcbC
gene_biotype: protein_coding
description:
  Isopenicillin N synthase (dioxygenase) protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: HRUBRI_0450
symbol: ALU87677.1
gene_biotype: protein_coding
description:
  Holliday junction resolvase protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: HRUBRI_0451
symbol: pyrR
gene_biotype: protein_coding
description:
  Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: HRUBRI_0452
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase (catalytic chain) protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: HRUBRI_0455
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: HRUBRI_0461
symbol: wecB
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 2-epimerase protein; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: HRUBRI_0464
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6 dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: HRUBRI_0465
symbol: fcl
gene_biotype: protein_coding
description:
  NAD-dependent epimerase/dehydratase protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: HRUBRI_0473
symbol: kdtA
gene_biotype: protein_coding
description:
  3-deoxy-d-manno-octulosonic-acid (KDO) transferase protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: HRUBRI_0482
symbol: acrA
gene_biotype: protein_coding
description:
  Acriflavin resistance lipoprotein A protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_0489
symbol: bacA
gene_biotype: protein_coding
description:
  Bacitracin resistance undecaprenol kinase 2 protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: HRUBRI_0492
symbol: trmB-2
gene_biotype: protein_coding
description:
  tRNA guanine-N(7)-methyltransferase protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: HRUBRI_0501
symbol: ALU87722.1
gene_biotype: protein_coding
description:
  Enzyme with a TIM-barrel fold protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: HRUBRI_0517
symbol: ALU87738.1
gene_biotype: protein_coding
description:
  Cation efflux protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: HRUBRI_0519
symbol: mntP
gene_biotype: protein_coding
description:
  Hypothetical protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: HRUBRI_0561
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: HRUBRI_0563
symbol: rlpB
gene_biotype: protein_coding
description:
  Lipoprotein B precursor transmembrane protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.


ensembl_gene_id: HRUBRI_0570
symbol: potA
gene_biotype: protein_coding
description:
  ABC-type spermidine/putrescine transport systems, ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_0571
symbol: cpdA-2
gene_biotype: protein_coding
description:
  cAMP phosphodiesterase protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: HRUBRI_0575
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: HRUBRI_0576
symbol: smpA
gene_biotype: protein_coding
description:
  Small protein A (tmRNA-binding) protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: HRUBRI_0578
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor transcription regulator protein; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: HRUBRI_0580
symbol: nadK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: HRUBRI_0582
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase (protoheme ferro-lyase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: HRUBRI_0584
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein 24 (HSP-70 cofactor)protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]


ensembl_gene_id: HRUBRI_0586
symbol: dnaJ
gene_biotype: protein_coding
description:
  Molecular chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between Dn [...]


ensembl_gene_id: HRUBRI_0587
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: HRUBRI_0594
symbol: cheR
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: HRUBRI_0595
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis-specific methylesterase protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: HRUBRI_0598
symbol: pcnB
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase/poly(A) polymerase protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: HRUBRI_0622
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: HRUBRI_0625
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, beta chain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: HRUBRI_0626
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase alpha chain protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: HRUBRI_0629
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis MoaC protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: HRUBRI_0635
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_0638
symbol: fbaA
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphate aldolase protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: HRUBRI_0639
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthase protein; Belongs to the SAICAR synthetase family.


ensembl_gene_id: HRUBRI_0640
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: HRUBRI_0641
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: HRUBRI_0642
symbol: sua5
gene_biotype: protein_coding
description:
  Translation factor (SUA5) protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: HRUBRI_0645
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrA protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: HRUBRI_0647
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: HRUBRI_0656
symbol: tonB-2
gene_biotype: protein_coding
description:
  TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: HRUBRI_0660
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: HRUBRI_0661
symbol: nudJ
gene_biotype: protein_coding
description:
  NTP pyrophosphohydrolase (NUDIX hydrolase) protein; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: HRUBRI_0663
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase precursor protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: HRUBRI_0665
symbol: pntB
gene_biotype: protein_coding
description:
  Transmembrane NAD(P) transhydrogenase (beta subunit) protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: HRUBRI_0666
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: HRUBRI_0671
symbol: ostA
gene_biotype: protein_coding
description:
  Organic solvent tolerance transmembrane protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: HRUBRI_0672
symbol: surA
gene_biotype: protein_coding
description:
  Parvulin-like peptidyl-prolyl cis-trans isomerase protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: HRUBRI_0674
symbol: pdxA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: HRUBRI_0675
symbol: ksgA
gene_biotype: protein_coding
description:
  S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: HRUBRI_0687
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase transmembrane protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: HRUBRI_0689
symbol: ybeY
gene_biotype: protein_coding
description:
  Metal-dependent hydrolase protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: HRUBRI_0691
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA modifying 2-methylthioadenine synthetase protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: HRUBRI_0696
symbol: rbsA
gene_biotype: protein_coding
description:
  ABC-type sugar transport system, ATPase component protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: HRUBRI_0697
symbol: ALU87917.1
gene_biotype: protein_coding
description:
  ABC-type sugar transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_0701
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta2-isopentenylpyrophosphate transferase protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: HRUBRI_0702
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: HRUBRI_0708
symbol: fdx
gene_biotype: protein_coding
description:
  Ferredoxin [4Fe-4S]-type protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: HRUBRI_0716
symbol: xerD
gene_biotype: protein_coding
description:
  Site specific integrase/recombinase protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: HRUBRI_0718
symbol: plsY
gene_biotype: protein_coding
description:
  Putative glycerol-3-phosphate acyltransferase PlsY protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: HRUBRI_0719
symbol: gcp
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: HRUBRI_0727
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: HRUBRI_0732
symbol: ALU87951.1
gene_biotype: protein_coding
description:
  Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: HRUBRI_0736
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: HRUBRI_0738
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma-70 factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: HRUBRI_0745
symbol: gabT-2
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_0756
symbol: livH-2
gene_biotype: protein_coding
description:
  ABC-type branched-chain amino acid transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_0764
symbol: glpD2
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase protein; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: HRUBRI_0765
symbol: ALU87982.1
gene_biotype: protein_coding
description:
  ABC-type sugar transport system, ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_0771
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: HRUBRI_0790
symbol: ALU88007.1
gene_biotype: protein_coding
description:
  GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: HRUBRI_0791
symbol: ALU88008.1
gene_biotype: protein_coding
description:
  ABC-type metal ion transport system, periplasmic component/surface antigen protein; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: HRUBRI_0793
symbol: metN
gene_biotype: protein_coding
description:
  ABC-type metal ion transport system, ATPase component protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HRUBRI_0795
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL (HSP60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: HRUBRI_0796
symbol: groES1
gene_biotype: protein_coding
description:
  Co-chaperonin GroES (HSP10) protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: HRUBRI_0818
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: HRUBRI_0821
symbol: deoC
gene_biotype: protein_coding
description:
  2-deoxyribose-5-phosphate aldolase protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: HRUBRI_0823
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: HRUBRI_0837
symbol: ALU88054.1
gene_biotype: protein_coding
description:
  ABC-type sugar transport system, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_0881
symbol: potA-2
gene_biotype: protein_coding
description:
  ABC-type spermidine/putrescine transport system, ATPase component protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HRUBRI_0884
symbol: ALU88101.1
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: HRUBRI_0902
symbol: ALU88118.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_0906
symbol: talB
gene_biotype: protein_coding
description:
  Transaldolase protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: HRUBRI_0908
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: HRUBRI_0910
symbol: edd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydratase protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: HRUBRI_0915
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase transmembrane protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: HRUBRI_0919
symbol: ALU88135.1
gene_biotype: protein_coding
description:
  Phospholipase D family protein; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.


ensembl_gene_id: HRUBRI_0924
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase protein; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: HRUBRI_0928
symbol: ALU88144.1
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: HRUBRI_0930
symbol: ALU88146.1
gene_biotype: protein_coding
description:
  Aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_0932
symbol: gabD-2
gene_biotype: protein_coding
description:
  NADP-dependent succinate-semialdehyde dehydrogenase protein; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: HRUBRI_0940
symbol: ALU88156.1
gene_biotype: protein_coding
description:
  Dipeptide/oligopeptide/nickel ABC transporter ATPase protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_0972
symbol: sodB
gene_biotype: protein_coding
description:
  Superoxide dismutase [Fe] protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: HRUBRI_0973
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: HRUBRI_0976
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: HRUBRI_0978
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: HRUBRI_0979
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: HRUBRI_0980
symbol: hppA
gene_biotype: protein_coding
description:
  H(+)-translocating pyrophosphatase protein; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: HRUBRI_0984
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: HRUBRI_0985
symbol: sun
gene_biotype: protein_coding
description:
  tRNA and rRNA cytosine-C5-methylase protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: HRUBRI_0993
symbol: lytB
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: HRUBRI_1023
symbol: lldD-3
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase protein; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.


ensembl_gene_id: HRUBRI_1032
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-Pal cell envelope complex subunit YbgF protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: HRUBRI_1033
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: HRUBRI_1034
symbol: tolB
gene_biotype: protein_coding
description:
  Periplasmic component of the Tol biopolymer transport system protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: HRUBRI_1037
symbol: tolQ
gene_biotype: protein_coding
description:
  MotA/TolQ/ExbB proton channel family protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: HRUBRI_1039
symbol: ALU88254.1
gene_biotype: protein_coding
description:
  Short-chain alcohol dehydrogenase protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HRUBRI_1040
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: HRUBRI_1041
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: HRUBRI_1042
symbol: ALU88257.1
gene_biotype: protein_coding
description:
  Cell division ZapA family protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: HRUBRI_1044
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: HRUBRI_1045
symbol: tsaA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: HRUBRI_1046
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose t [...]


ensembl_gene_id: HRUBRI_1047
symbol: ALU88262.1
gene_biotype: protein_coding
description:
  Composite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein.


ensembl_gene_id: HRUBRI_1053
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase transmembrane protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: HRUBRI_1054
symbol: secD
gene_biotype: protein_coding
description:
  Export membrane SecD transmembrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: HRUBRI_1055
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: HRUBRI_1059
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/peroxidase protein; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: HRUBRI_1070
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: HRUBRI_1071
symbol: pstS
gene_biotype: protein_coding
description:
  ABC-type phosphate transport system, periplasmic component protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: HRUBRI_1072
symbol: pstC
gene_biotype: protein_coding
description:
  ABC-type phosphate transport system, permease component protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: HRUBRI_1074
symbol: pstB
gene_biotype: protein_coding
description:
  ABC-type phosphate transport system, ATPase component protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: HRUBRI_1080
symbol: ALU88295.1
gene_biotype: protein_coding
description:
  2-keto-4-pentenoate hydratase 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) protein.


ensembl_gene_id: HRUBRI_1109
symbol: ALU88321.1
gene_biotype: protein_coding
description:
  LysR family transcriptional regulator protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HRUBRI_1114
symbol: ALU88326.1
gene_biotype: protein_coding
description:
  VRR-NUC domain-containing protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: HRUBRI_1118
symbol: bcsB
gene_biotype: protein_coding
description:
  Bacterial cellulose synthase subunit, cyclic di-GMP binding protein; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: HRUBRI_1132
symbol: catB
gene_biotype: protein_coding
description:
  Muconate cycloisomerase protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: HRUBRI_1161
symbol: ALU88373.1
gene_biotype: protein_coding
description:
  ABC-type amino acid transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_1162
symbol: ALU88374.1
gene_biotype: protein_coding
description:
  ABC-type amino acid transport system, composite ATP-binding/permease components protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_1171
symbol: ALU88383.1
gene_biotype: protein_coding
description:
  Multidrug efflux system transporter AcrA-like protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_1200
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: HRUBRI_1202
symbol: ftsJ
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase (Cell division protein FtsJ) protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: HRUBRI_1203
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent metalloprotease FtsH protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: HRUBRI_1204
symbol: folP
gene_biotype: protein_coding
description:
  7,8-dihydropteroate synthase protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: HRUBRI_1205
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: HRUBRI_1212
symbol: mviN
gene_biotype: protein_coding
description:
  Virulence factor transmembrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: HRUBRI_1218
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: HRUBRI_1221
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: HRUBRI_1222
symbol: coaBC
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine synthetase/decarboxylase protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: HRUBRI_1223
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: HRUBRI_1224
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: HRUBRI_1231
symbol: ALU88443.1
gene_biotype: protein_coding
description:
  ABC-type monosaccharides transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_1232
symbol: ALU88444.1
gene_biotype: protein_coding
description:
  ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_1238
symbol: rmsE
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: HRUBRI_1241
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde 3-phosphate dehydrogenase protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: HRUBRI_1244
symbol: glnE
gene_biotype: protein_coding
description:
  Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory r [...]


ensembl_gene_id: HRUBRI_1248
symbol: aroG
gene_biotype: protein_coding
description:
  3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: HRUBRI_1251
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: HRUBRI_1252
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase protein; Belongs to the argininosuccinate synthase family. Type 2 subfamily.


ensembl_gene_id: HRUBRI_1253
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: HRUBRI_1255
symbol: rsgA
gene_biotype: protein_coding
description:
  GTPase RsgA protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: HRUBRI_1258
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease (3'->5' exoribonuclease) protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: HRUBRI_1260
symbol: srkA
gene_biotype: protein_coding
description:
  Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: HRUBRI_1276
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: HRUBRI_1277
symbol: gshA-2
gene_biotype: protein_coding
description:
  Gamma-glutamate-cysteine ligase protein; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: HRUBRI_1278
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: HRUBRI_1279
symbol: ALU88491.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: HRUBRI_1303
symbol: nadX
gene_biotype: protein_coding
description:
  Putative Aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.


ensembl_gene_id: HRUBRI_1329
symbol: fdsC
gene_biotype: protein_coding
description:
  Formate dehydrogenase regulatory subunit protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: HRUBRI_1332
symbol: ALU88543.1
gene_biotype: protein_coding
description:
  Enzyme of extracellular polysaccharide biosynthesis protein/ antibiotic biosynthesis monooxygenase protein.


ensembl_gene_id: HRUBRI_1343
symbol: ALU88554.1
gene_biotype: protein_coding
description:
  ABC-type amino-acid transport system, periplasmic component protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HRUBRI_1355
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: HRUBRI_1356
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (Guanine-N(1)-)-methyltransferase protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: HRUBRI_1357
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: HRUBRI_1359
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis transmembrane protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: HRUBRI_1361
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase class II (fumarase) protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: HRUBRI_1368
symbol: ALU88579.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_1369
symbol: ALU88580.1
gene_biotype: protein_coding
description:
  Cation/multidrug efflux pump transmembrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: HRUBRI_1370
symbol: ALU88581.1
gene_biotype: protein_coding
description:
  Cation/multidrug efflux pump protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: HRUBRI_1389
symbol: fumA
gene_biotype: protein_coding
description:
  Fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: HRUBRI_1391
symbol: acs-2
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: HRUBRI_1471
symbol: dppD2
gene_biotype: protein_coding
description:
  ABC-type dipeptide/oligopeptide transport system, ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_1472
symbol: dppF2
gene_biotype: protein_coding
description:
  ABC-type oligopeptide transport system, ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_1476
symbol: ALU88685.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: HRUBRI_1477
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H (lipoate-binding) protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: HRUBRI_1478
symbol: ssuD
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase protein; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: HRUBRI_1489
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: HRUBRI_1509
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: HRUBRI_1510
symbol: fdx-2
gene_biotype: protein_coding
description:
  Ferredoxin [4Fe-4S]-type protein / putative RnfB protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: HRUBRI_1513
symbol: fdxA
gene_biotype: protein_coding
description:
  Ferredoxin protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: HRUBRI_1515
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase protein; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: HRUBRI_1517
symbol: ALU88726.1
gene_biotype: protein_coding
description:
  Dehydrogenase oxidoreductase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HRUBRI_1537
symbol: ssuB
gene_biotype: protein_coding
description:
  ABC-type alkanesulfonates transport system, ATPase component protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HRUBRI_1541
symbol: cysU
gene_biotype: protein_coding
description:
  ABC-type sulfate transport system, permease component protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: HRUBRI_1543
symbol: cysA
gene_biotype: protein_coding
description:
  ABC-type sulfate/molybdate transport system, ATPase component protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HRUBRI_1548
symbol: livH-4
gene_biotype: protein_coding
description:
  ABC-type branched-chain aminoacid transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_1557
symbol: ada
gene_biotype: protein_coding
description:
  Bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase protein.


ensembl_gene_id: HRUBRI_1569
symbol: ALU88777.1
gene_biotype: protein_coding
description:
  Anaerobic (selenocysteine-containing) formate dehydrogenase protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HRUBRI_1576
symbol: ALU88784.1
gene_biotype: protein_coding
description:
  Putative membrane-associated lipoprotein involved in thiamine biosynthesis ApbE protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: HRUBRI_1589
symbol: rhlE
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: HRUBRI_1593
symbol: lasT
gene_biotype: protein_coding
description:
  tRNA/rRNA methyltransferase protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: HRUBRI_1594
symbol: rsuA
gene_biotype: protein_coding
description:
  Ribosomal small subunit pseudouridine synthase A protein; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: HRUBRI_1596
symbol: ALU88804.1
gene_biotype: protein_coding
description:
  Redox regulated molecular chaperone heat-shock-like protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: HRUBRI_1608
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase oxidoreductase protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: HRUBRI_1611
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: HRUBRI_1612
symbol: pssA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: HRUBRI_1619
symbol: dsd
gene_biotype: protein_coding
description:
  D-serine dehydratase; Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase protein.


ensembl_gene_id: HRUBRI_1625
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: HRUBRI_1626
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: HRUBRI_1631
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: HRUBRI_1636
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: HRUBRI_1637
symbol: ALU88845.1
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: HRUBRI_1639
symbol: nuoA
gene_biotype: protein_coding
description:
  Transmembrane NADH dehydrogenase I (Chain A) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: HRUBRI_1640
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase I (Chain B) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: HRUBRI_1641
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase I (Chain C) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: HRUBRI_1642
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase I (Chain D) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: HRUBRI_1644
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH dehydrogenase I (chain F) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: HRUBRI_1645
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH dehydrogenase I (Chain G) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: HRUBRI_1646
symbol: nuoH
gene_biotype: protein_coding
description:
  Transmembrane NADH dehydrogenase I (chain H) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: HRUBRI_1647
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase I (Chain I) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: HRUBRI_1648
symbol: nuoJ
gene_biotype: protein_coding
description:
  Transmembrane NADH dehydrogenase I (Chain J) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: HRUBRI_1649
symbol: nuoK
gene_biotype: protein_coding
description:
  Transmembrane NADH dehydrogenase I (Chain K) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: HRUBRI_1652
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH-ubiquinone (chain N) oxidoreductase protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: HRUBRI_1655
symbol: etf
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase protein; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: HRUBRI_1659
symbol: livG-5
gene_biotype: protein_coding
description:
  ABC-type branched-chain amino acid transport system, ATPase component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_1674
symbol: htpG
gene_biotype: protein_coding
description:
  HSP90 family high temperature molecular chaperone G protein; Molecular chaperone. Has ATPase activity.


ensembl_gene_id: HRUBRI_1693
symbol: ibpA
gene_biotype: protein_coding
description:
  Molecular chaperone (16 kDa) heat shock protein A; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: HRUBRI_1704
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV (subunit A) protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: HRUBRI_1706
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: HRUBRI_1719
symbol: ALU88924.1
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: HRUBRI_1723
symbol: ALU88928.1
gene_biotype: protein_coding
description:
  ABC-type transport system, duplicated ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_1743
symbol: vacB-2
gene_biotype: protein_coding
description:
  Exoribonuclease RNAse R protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: HRUBRI_1744
symbol: spoU
gene_biotype: protein_coding
description:
  tRNA/rRNA methyltransferase protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: HRUBRI_1746
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: HRUBRI_1747
symbol: ppiB2
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: HRUBRI_1753
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase (alpha subunit) protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: HRUBRI_1754
symbol: tilS
gene_biotype: protein_coding
description:
  PP-loop superfamily ATPase, implicated in cell cycle control, protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: HRUBRI_1761
symbol: ALU88965.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease transmembrane protein.


ensembl_gene_id: HRUBRI_1764
symbol: moeA-2
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: HRUBRI_1765
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: HRUBRI_1766
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: HRUBRI_1767
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: HRUBRI_1768
symbol: rluC
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase C protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: HRUBRI_1776
symbol: nadE
gene_biotype: protein_coding
description:
  Glutamine-dependent NAD synthetase protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: HRUBRI_1787
symbol: lolA
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein-sorting protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: HRUBRI_1795
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: HRUBRI_1803
symbol: maf
gene_biotype: protein_coding
description:
  Nucleotide-binding, septum formation inhibitor protein, Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: HRUBRI_1806
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: HRUBRI_1807
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase III protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: HRUBRI_1809
symbol: fabG-4
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-Protein] reductase oxidoreductase protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HRUBRI_1811
symbol: fabF1
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: HRUBRI_1813
symbol: rpoE-2
gene_biotype: protein_coding
description:
  RNA polymerase sigma-E factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HRUBRI_1816
symbol: degQ
gene_biotype: protein_coding
description:
  Periplasmic trypsin-like serine protease, containing C-terminal PDZ domain protein; Belongs to the peptidase S1C family.


ensembl_gene_id: HRUBRI_1818
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding elongation factor protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: HRUBRI_1820
symbol: rnc
gene_biotype: protein_coding
description:
  dsRNA-specific ribonuclease (RNAse III) protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: HRUBRI_1821
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding ERA protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: HRUBRI_1823
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: HRUBRI_1824
symbol: acpS
gene_biotype: protein_coding
description:
  Phosphopantetheinyl transferase (holo-ACP synthase) protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: HRUBRI_1825
symbol: nagZ
gene_biotype: protein_coding
description:
  beta-N-acetylhexosaminidase protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: HRUBRI_1826
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C (SOS response DNA repair protein) protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: HRUBRI_1827
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol-glycerol-3-Phosphate 3-Phosphatidyltransferase transmembrane protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: HRUBRI_1835
symbol: cobT
gene_biotype: protein_coding
description:
  nicotinate-nucleotide-dimethylbenzimidazole-P phosphoribosyltransferase protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: HRUBRI_1836
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5-phosphate synthase protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: HRUBRI_1848
symbol: kefB
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system K+/H+ antiporter transmembrane protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: HRUBRI_1849
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase beta chain) protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: HRUBRI_1858
symbol: relA
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase I (GTP pyrophosphokinase) protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: HRUBRI_1863
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: HRUBRI_1864
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor protein; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: HRUBRI_1866
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal subunit L20 protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: HRUBRI_1867
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase alpha chain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: HRUBRI_1868
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase beta chain protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: HRUBRI_1869
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor alpha-subunit protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: HRUBRI_1887
symbol: epsP
gene_biotype: protein_coding
description:
  UDP-N-acetyl-d-mannosaminuronic acid transferase protein; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: HRUBRI_1894
symbol: ALU89087.1
gene_biotype: protein_coding
description:
  Sugar phosphate isomerase (involved in capsule formation) protein; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: HRUBRI_1908
symbol: cheR-2
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: HRUBRI_1909
symbol: cheD-2
gene_biotype: protein_coding
description:
  Chemotaxis protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: HRUBRI_1912
symbol: cheZ
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase, CheZ protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: HRUBRI_1913
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthesis FlhB transmembrane protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: HRUBRI_1914
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis FlhA transmembrane protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: HRUBRI_1917
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor for flagellar operon (sigma-F factor) protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: HRUBRI_1921
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod FlgB protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: HRUBRI_1923
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: HRUBRI_1927
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar basal-body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: HRUBRI_1928
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar basal-body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: HRUBRI_1932
symbol: fliR
gene_biotype: protein_coding
description:
  FliR component of the flagellar biosynthesis pathway; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: HRUBRI_1933
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic FliQ protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: HRUBRI_1934
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP precursor protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: HRUBRI_1938
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar FliL transmembrane protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: HRUBRI_1944
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: HRUBRI_1946
symbol: ycgR
gene_biotype: protein_coding
description:
  YcgR and PilZ families (type IV pilus assembly PilZ) protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: HRUBRI_1951
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar hook-associated 2 protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: HRUBRI_1953
symbol: fliC
gene_biotype: protein_coding
description:
  Flagellin protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: HRUBRI_1955
symbol: lexA
gene_biotype: protein_coding
description:
  SOS-response transcription repressor (RecA-mediated autopeptidases) protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: HRUBRI_1957
symbol: priB
gene_biotype: protein_coding
description:
  Primosomal replication N protein; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: HRUBRI_1958
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal subunit S18 protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: HRUBRI_1960
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: HRUBRI_1977
symbol: moeA-3
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: HRUBRI_1982
symbol: mntH
gene_biotype: protein_coding
description:
  NRAMP family Mn2+/Fe2+ transporter protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: HRUBRI_1991
symbol: crcB
gene_biotype: protein_coding
description:
  Integral membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: HRUBRI_1992
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease subunit (heat-shock) protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: HRUBRI_1994
symbol: menG
gene_biotype: protein_coding
description:
  S-adenosylmethionine:2-demethylmenaquinone methyltransferase protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: HRUBRI_1998
symbol: modB1
gene_biotype: protein_coding
description:
  ABC-type molybdate transport system, permease component protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: HRUBRI_2006
symbol: greA-2
gene_biotype: protein_coding
description:
  Transcription elongation/transcript cleavage factor protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: HRUBRI_2008
symbol: acpD
gene_biotype: protein_coding
description:
  Acyl-carrier-protein phosphodiesterase protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: HRUBRI_2010
symbol: spoT
gene_biotype: protein_coding
description:
  GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: HRUBRI_2011
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase omega subunit protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: HRUBRI_2014
symbol: rph
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase (ribonuclease PH) protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: HRUBRI_2015
symbol: ALU89207.1
gene_biotype: protein_coding
description:
  Xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: HRUBRI_2016
symbol: hemN
gene_biotype: protein_coding
description:
  Anaerobic coproporphyrinogen III oxidase oxidoreductase protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: HRUBRI_2019
symbol: sodC
gene_biotype: protein_coding
description:
  Cu/Zn superoxide dismutase protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: HRUBRI_2032
symbol: dadX
gene_biotype: protein_coding
description:
  Alanine racemase protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: HRUBRI_2033
symbol: radA
gene_biotype: protein_coding
description:
  ATP-dependent serine protease protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: HRUBRI_2039
symbol: ALU89230.1
gene_biotype: protein_coding
description:
  ABC-type amino acid transport/signal transduction system, periplasmic component/domain protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HRUBRI_2041
symbol: hemK
gene_biotype: protein_coding
description:
  Adenine-specific methylase/methyltransferase protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: HRUBRI_2042
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: HRUBRI_2044
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase protein; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: HRUBRI_2047
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation SMC ATPase protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: HRUBRI_2048
symbol: ALU89239.1
gene_biotype: protein_coding
description:
  Transmembrane protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.


ensembl_gene_id: HRUBRI_2049
symbol: lig
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase (contains BRCT domain type II) protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: HRUBRI_2051
symbol: def
gene_biotype: protein_coding
description:
  N-formylmethionyl-tRNA deformylase/polypeptide deformylase protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: HRUBRI_2057
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyltransferase protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: HRUBRI_2060
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor TS (EF-TS) protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: HRUBRI_2062
symbol: rrf
gene_biotype: protein_coding
description:
  Ribosome recycling factor (ribosome releasing factor) protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: HRUBRI_2063
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: HRUBRI_2065
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: HRUBRI_2067
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane /protective OMA87 antigen protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: HRUBRI_2069
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-3-hydroxymyristoyl glucosamine N-acyltransferase protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: HRUBRI_2070
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: HRUBRI_2071
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: HRUBRI_2072
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: HRUBRI_2076
symbol: ALU89267.1
gene_biotype: protein_coding
description:
  ATP-binding protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: HRUBRI_2077
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase/pyruvate phosphate dikinase protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: HRUBRI_2084
symbol: smpB
gene_biotype: protein_coding
description:
  tmRNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches t [...]


ensembl_gene_id: HRUBRI_2087
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: HRUBRI_2091
symbol: queE
gene_biotype: protein_coding
description:
  Organic radical activating enzyme protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: HRUBRI_2093
symbol: tadA
gene_biotype: protein_coding
description:
  Cytosine/adenosine deaminases protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: HRUBRI_2097
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: HRUBRI_2100
symbol: nadB
gene_biotype: protein_coding
description:
  L-aspartate oxidase (quinolinate synthetase B) protein; Catalyzes the oxidation of L-aspartate to iminoaspartate.


ensembl_gene_id: HRUBRI_2101
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2 protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: HRUBRI_2117
symbol: nnrE
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: HRUBRI_2119
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: HRUBRI_2123
symbol: ispZ
gene_biotype: protein_coding
description:
  Intracellular septation A protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: HRUBRI_2125
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: HRUBRI_2154
symbol: ALU89345.1
gene_biotype: protein_coding
description:
  Two component heavy metal sensor histidine kinase protein; Member of a two-component regulatory system.


ensembl_gene_id: HRUBRI_2181
symbol: cyoB
gene_biotype: protein_coding
description:
  Cytochrome o ubiquinol oxidase subunit I protein; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: HRUBRI_2192
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: HRUBRI_2193
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_2194
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate (7-keto-8-aminopelargonate) synthase protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: HRUBRI_2196
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: HRUBRI_2212
symbol: czcA
gene_biotype: protein_coding
description:
  Cobalt-zinc-cadmium resistance cation efflux system transmembrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: HRUBRI_2213
symbol: ALU89404.1
gene_biotype: protein_coding
description:
  Cation transporter transmembrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_2228
symbol: ALU89419.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase component, protein.


ensembl_gene_id: HRUBRI_2247
symbol: ALU89437.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 subunit protein; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HRUBRI_2255
symbol: ALU89445.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: HRUBRI_2265
symbol: ALU89455.1
gene_biotype: protein_coding
description:
  Family efflux transporter membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_2266
symbol: macB
gene_biotype: protein_coding
description:
  ABC-type antimicrobial peptide transport system, ATPase component protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: HRUBRI_2301
symbol: ALU89487.1
gene_biotype: protein_coding
description:
  Transcription regulator, LysR family protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HRUBRI_2302
symbol: tam
gene_biotype: protein_coding
description:
  Trans-aconitate methyltransferase protein; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.


ensembl_gene_id: HRUBRI_2329
symbol: ALU89514.1
gene_biotype: protein_coding
description:
  Transcriptional regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.


ensembl_gene_id: HRUBRI_2342
symbol: csdB
gene_biotype: protein_coding
description:
  Selenocysteine lyase protein; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_2353
symbol: nifS
gene_biotype: protein_coding
description:
  Cysteine desulfurase (NifS) protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: HRUBRI_2354
symbol: nifU
gene_biotype: protein_coding
description:
  Fe-S cluster formation NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: HRUBRI_2357
symbol: hscA
gene_biotype: protein_coding
description:
  Molecular chaperone, Hsp70 family, protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: HRUBRI_2360
symbol: nifW
gene_biotype: protein_coding
description:
  Nitrogenase stabilizing/protective protein; May protect the nitrogenase Fe-Mo protein from oxidative damage; Belongs to the NifW family.


ensembl_gene_id: HRUBRI_2363
symbol: fixC
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.


ensembl_gene_id: HRUBRI_2365
symbol: modC
gene_biotype: protein_coding
description:
  Molybdate ABC transporter ATPase; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: HRUBRI_2366
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: HRUBRI_2375
symbol: nifK
gene_biotype: protein_coding
description:
  Nitrogenase molybdenum-iron protein beta chain protein; This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation; Belongs to the NifD/NifK/NifE/NifN family.


ensembl_gene_id: HRUBRI_2377
symbol: nifH
gene_biotype: protein_coding
description:
  Dinitrogenase reductase NifH protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.


ensembl_gene_id: HRUBRI_2405
symbol: ALU89590.1
gene_biotype: protein_coding
description:
  ABC superfamily ATP binding cassette transporter, membrane protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_2406
symbol: ALU89591.1
gene_biotype: protein_coding
description:
  Transmembrane ABC transporter protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_2480
symbol: ALU89665.1
gene_biotype: protein_coding
description:
  Class III aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_2485
symbol: ALU89670.1
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase alpha subunit protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: HRUBRI_2486
symbol: ALU89671.1
gene_biotype: protein_coding
description:
  NADP transhydrogenase beta subunit protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: HRUBRI_2493
symbol: metN-3
gene_biotype: protein_coding
description:
  Metal ion ABC transporter ATPase protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HRUBRI_2504
symbol: ALU89689.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit protein.


ensembl_gene_id: HRUBRI_2520
symbol: rbsD-2
gene_biotype: protein_coding
description:
  ABC-type sugar transport system, auxiliary component protein, RbsD / FucU transport protein family; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: HRUBRI_2523
symbol: ALU89705.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_2527
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: HRUBRI_2536
symbol: glnH-2
gene_biotype: protein_coding
description:
  Glutamine ABC transporter periplasmic protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HRUBRI_2541
symbol: dld
gene_biotype: protein_coding
description:
  FAD-dependent D-lactate dehydrogenase protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: HRUBRI_2542
symbol: ALU89724.1
gene_biotype: protein_coding
description:
  ABC transporter membrane protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_2545
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: HRUBRI_2554
symbol: ALU89736.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter/signal transduction system periplasmic protein/domain-containing protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HRUBRI_2563
symbol: ku
gene_biotype: protein_coding
description:
  Ku domain containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: HRUBRI_2579
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: HRUBRI_2603
symbol: hemK-2
gene_biotype: protein_coding
description:
  Methylase of polypeptide chain release factors protein; Belongs to the methyltransferase superfamily.


ensembl_gene_id: HRUBRI_2659
symbol: ALU89836.1
gene_biotype: protein_coding
description:
  DNA-binding HU-beta protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: HRUBRI_2660
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease LA protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: HRUBRI_2661
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease (ATP-binding specificity subunit) protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: HRUBRI_2662
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease (proteolytic subunit) protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: HRUBRI_2663
symbol: tig
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis/trans isomerase (trigger factor) protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: HRUBRI_2683
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: HRUBRI_2684
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: HRUBRI_2689
symbol: plcN
gene_biotype: protein_coding
description:
  Non-hemolytic phospholipase C (phosphatidylcholine choline phospho hydrolase) signal peptide protein.


ensembl_gene_id: HRUBRI_2690
symbol: ALU89866.1
gene_biotype: protein_coding
description:
  tonB domain protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: HRUBRI_2697
symbol: ugpE
gene_biotype: protein_coding
description:
  ABC-type glycerol-3-phosphate transport system, permease component protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: HRUBRI_2700
symbol: dctA
gene_biotype: protein_coding
description:
  C4-dicarboxylate transport transmembrane protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: HRUBRI_2707
symbol: phnX
gene_biotype: protein_coding
description:
  Phosphonoacetaldehyde phosphonohydrolase protein; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.


ensembl_gene_id: HRUBRI_2717
symbol: amiE
gene_biotype: protein_coding
description:
  Aliphatic amidase protein; Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.


ensembl_gene_id: HRUBRI_2730
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: HRUBRI_2732
symbol: cobD-2
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis (CobD/CbiB) protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: HRUBRI_2733
symbol: cobP
gene_biotype: protein_coding
description:
  Bifunctional cobinamide kinase/cobinamide phosphate guanylyltransferase protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: HRUBRI_2736
symbol: cobA
gene_biotype: protein_coding
description:
  cob(I)alamin adenosyltransferase protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: HRUBRI_2741
symbol: cbiL
gene_biotype: protein_coding
description:
  Precorrin-2 C20-methyltransferase protein; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.


ensembl_gene_id: HRUBRI_2742
symbol: cbiD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis CbiD transmembrane protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: HRUBRI_2761
symbol: serA-2
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HRUBRI_2765
symbol: mdcB
gene_biotype: protein_coding
description:
  triphosphoribosyl-dephospho-CoA synthetase protein; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.


ensembl_gene_id: HRUBRI_2783
symbol: rpoE-4
gene_biotype: protein_coding
description:
  RNA polymerase sigma-E factor (sigma-24) protein; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: HRUBRI_2790
symbol: emrB
gene_biotype: protein_coding
description:
  Multidrug resistance B (translocase) transmembrane protein; Belongs to the major facilitator superfamily.


ensembl_gene_id: HRUBRI_2804
symbol: adhC-2
gene_biotype: protein_coding
description:
  Bifunctional glutathione-dependent formaldehyde dehydrogenase/alcohol dehydrogenase class III oxidoreductase protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: HRUBRI_2821
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division, septum formation initiator, FtsB protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: HRUBRI_2822
symbol: eno
gene_biotype: protein_coding
description:
  Enolase (2-Phosphoglycerate dehydratase) protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: HRUBRI_2823
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: HRUBRI_2828
symbol: lolD
gene_biotype: protein_coding
description:
  ABC-type lipoprotein release transport system, ATPase component protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: HRUBRI_2836
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2 (RF-2) protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: HRUBRI_2843
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: HRUBRI_2878
symbol: nthB
gene_biotype: protein_coding
description:
  Nitrile hydratase subunit beta protein; NHase catalyzes the hydration of various nitrile compounds to the corresponding amides; Belongs to the nitrile hydratase subunit beta family.


ensembl_gene_id: HRUBRI_2883
symbol: atoB
gene_biotype: protein_coding
description:
  acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase) protein; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: HRUBRI_2897
symbol: tolC
gene_biotype: protein_coding
description:
  Outer membrane channel lipoprotein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.


ensembl_gene_id: HRUBRI_2917
symbol: ALU90089.1
gene_biotype: protein_coding
description:
  ABC-type transport system involved in resistance to organic solvents, periplasmic component protein.


ensembl_gene_id: HRUBRI_2929
symbol: nirB
gene_biotype: protein_coding
description:
  Nitrite reductase NADPH (Large subunit) oxidoreductase protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: HRUBRI_2932
symbol: nasA
gene_biotype: protein_coding
description:
  Assimilatory nitrate reductase large subunit protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: HRUBRI_2942
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3 (RF-3) protein; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: HRUBRI_2943
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase protein; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: HRUBRI_2946
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: HRUBRI_2947
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: HRUBRI_2948
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: HRUBRI_2965
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: HRUBRI_2966
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: HRUBRI_2969
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: HRUBRI_2970
symbol: hfq
gene_biotype: protein_coding
description:
  RNA chaperone Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: HRUBRI_2971
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: HRUBRI_2972
symbol: bamB
gene_biotype: protein_coding
description:
  Lipoprotein transmembrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: HRUBRI_2975
symbol: gcpE
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: HRUBRI_2977
symbol: rlmN
gene_biotype: protein_coding
description:
  Fe-S-cluster redox enzyme protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: HRUBRI_2978
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside-diphosphate kinase protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: HRUBRI_2981
symbol: rumT
gene_biotype: protein_coding
description:
  23S rRNA (Uracil-5-)-methyltransferase protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: HRUBRI_2982
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma S (sigma38) factor protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: HRUBRI_2984
symbol: pcm-2
gene_biotype: protein_coding
description:
  protein-L-isoaspartate carboxylmethyltransferase protein; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: HRUBRI_2985
symbol: surE
gene_biotype: protein_coding
description:
  Stationary-phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: HRUBRI_2992
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: HRUBRI_2996
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase Fe-S subunit protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: HRUBRI_2997
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase flavoprotein subunit protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: HRUBRI_3001
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: HRUBRI_3004
symbol: acnA-2
gene_biotype: protein_coding
description:
  Aconitate hydratase protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.


ensembl_gene_id: HRUBRI_3013
symbol: flhC
gene_biotype: protein_coding
description:
  Flagellar transcription activator regulator protein; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: HRUBRI_3014
symbol: flhD
gene_biotype: protein_coding
description:
  Flagellar transcription activator protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: HRUBRI_3017
symbol: rimO
gene_biotype: protein_coding
description:
  2-methylthioadenine synthetase protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: HRUBRI_3019
symbol: phbB
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HRUBRI_3025
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: HRUBRI_3026
symbol: bamD
gene_biotype: protein_coding
description:
  Transmembrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: HRUBRI_3035
symbol: cheB-3
gene_biotype: protein_coding
description:
  Protein-glutamate methylesterase protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: HRUBRI_3043
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair ATP-dependent coupling factor (helicase superfamily II) protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: HRUBRI_3044
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: HRUBRI_3045
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: HRUBRI_3062
symbol: sunT
gene_biotype: protein_coding
description:
  ATP-binding cassette, subfamily C, bacterial LapB; ABC-type bacteriocin/lantibiotic exporter, containing an N-terminal double-glycine peptidase domain protein.


ensembl_gene_id: HRUBRI_3066
symbol: msrA-2
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: HRUBRI_3067
symbol: yedZ
gene_biotype: protein_coding
description:
  Sulfite oxidase transmembrane subunit YedZ protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase cat [...]


ensembl_gene_id: HRUBRI_3068
symbol: msrP
gene_biotype: protein_coding
description:
  Sulfite oxidase protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and  [...]


ensembl_gene_id: HRUBRI_3070
symbol: czcS-2
gene_biotype: protein_coding
description:
  Cobalt/zinc/cadmium resistance two component transmembrane sensor histidine kinase protein; Member of a two-component regulatory system.


ensembl_gene_id: HRUBRI_3080
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: HRUBRI_3097
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: HRUBRI_3098
symbol: mrp
gene_biotype: protein_coding
description:
  ATPase involved in chromosome partitioning protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: HRUBRI_3099
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: HRUBRI_3102
symbol: ALU90265.1
gene_biotype: protein_coding
description:
  ABC-type sugar transport systems, ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_3108
symbol: ALU90271.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: HRUBRI_3109
symbol: panC
gene_biotype: protein_coding
description:
  Panthothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: HRUBRI_3112
symbol: ALU90275.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HRUBRI_3114
symbol: cheZ-2
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: HRUBRI_3122
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: HRUBRI_3127
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: HRUBRI_3138
symbol: prpB
gene_biotype: protein_coding
description:
  Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: HRUBRI_3149
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen assimilation transcription activator protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: HRUBRI_3159
symbol: hscA-2
gene_biotype: protein_coding
description:
  Molecular chaperone protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: HRUBRI_3161
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: HRUBRI_3163
symbol: iscU
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: HRUBRI_3164
symbol: iscS1
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: HRUBRI_3173
symbol: selU
gene_biotype: protein_coding
description:
  tRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: HRUBRI_3178
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: HRUBRI_3183
symbol: ALU90344.1
gene_biotype: protein_coding
description:
  ABC-type Mn2+/Zn2+ transport system, periplasmic component protein; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: HRUBRI_3194
symbol: dppD1
gene_biotype: protein_coding
description:
  ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_3213
symbol: fixP
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome c oxidase subunit III transmembrane protein; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: HRUBRI_3216
symbol: fixN
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome c oxidase, subunit I transmembrane protein; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: HRUBRI_3220
symbol: hemN-2
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: HRUBRI_3226
symbol: yhhQ
gene_biotype: protein_coding
description:
  Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: HRUBRI_3243
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: HRUBRI_3244
symbol: bpt
gene_biotype: protein_coding
description:
  arginyl-tRNA:protein arginylyltransferase protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: HRUBRI_3245
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: HRUBRI_3247
symbol: chaC
gene_biotype: protein_coding
description:
  Cation transport regulator protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: HRUBRI_3265
symbol: uraH
gene_biotype: protein_coding
description:
  Transthyreretyn-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: HRUBRI_3280
symbol: guaD
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: HRUBRI_3285
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: HRUBRI_3292
symbol: dapA-3
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: HRUBRI_3293
symbol: trpS-2
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HRUBRI_3302
symbol: purF
gene_biotype: protein_coding
description:
  Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: HRUBRI_3305
symbol: folC
gene_biotype: protein_coding
description:
  Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: HRUBRI_3306
symbol: accD-2
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: HRUBRI_3307
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: HRUBRI_3308
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase (beta chain) protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: HRUBRI_3310
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: HRUBRI_3312
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: HRUBRI_3313
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase oxidoreductase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: HRUBRI_3314
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase (small subunit) protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: HRUBRI_3315
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase (large subunit) protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: HRUBRI_3317
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: HRUBRI_3326
symbol: pldA
gene_biotype: protein_coding
description:
  Phospholipase A1; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: HRUBRI_3329
symbol: potA-3
gene_biotype: protein_coding
description:
  ABC-type spermidine/putrescine transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_3342
symbol: nhaP
gene_biotype: protein_coding
description:
  Na+(K+)/H+ antiporter protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: HRUBRI_3351
symbol: argM
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: HRUBRI_3355
symbol: serA-3
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HRUBRI_3375
symbol: cynT
gene_biotype: protein_coding
description:
  Carbonic anhydrase protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: HRUBRI_3383
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: HRUBRI_3384
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: HRUBRI_3386
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase protein; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: HRUBRI_3408
symbol: ALU90568.1
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, response regulator TctD; Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain protein.


ensembl_gene_id: HRUBRI_3424
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III, epsilon subunit, protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: HRUBRI_3427
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: HRUBRI_3441
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: HRUBRI_3452
symbol: livH-8
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter permease; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_3453
symbol: livFGM
gene_biotype: protein_coding
description:
  ABC transporter system, composite ATP-binding/permease components protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_3457
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthetase protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: HRUBRI_3460
symbol: ALU90619.1
gene_biotype: protein_coding
description:
  Membrane-fusion protein, RND family efflux transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_3461
symbol: mdoH
gene_biotype: protein_coding
description:
  Glucans biosynthesis glucosyltransferase H; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: HRUBRI_3462
symbol: mdoG
gene_biotype: protein_coding
description:
  Periplasmic glucans biosynthesis G protein; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: HRUBRI_3463
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase oxidoreductase protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: HRUBRI_3469
symbol: arsB-2
gene_biotype: protein_coding
description:
  Arsenical pump membrane protein, Ars family; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.


ensembl_gene_id: HRUBRI_3477
symbol: tolC-4
gene_biotype: protein_coding
description:
  Outer membrane efflux channel lipoprotein, type I secretion system; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.


ensembl_gene_id: HRUBRI_3480
symbol: yggX
gene_biotype: protein_coding
description:
  Fe-S cluster protector protein, Fe(2+) trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: HRUBRI_3525
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: HRUBRI_3526
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: HRUBRI_3527
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: HRUBRI_3528
symbol: rlmH
gene_biotype: protein_coding
description:
  Methyltransferase protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: HRUBRI_3529
symbol: maf-2
gene_biotype: protein_coding
description:
  Inhibition of septum formation nucleotide-binding protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: HRUBRI_3533
symbol: msbA
gene_biotype: protein_coding
description:
  Multidrug ABC transporter ATPase/permease; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: HRUBRI_3543
symbol: gltX-2
gene_biotype: protein_coding
description:
  Glutamyl/glutaminyl-tRNA synthetase protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: HRUBRI_3548
symbol: ubiD
gene_biotype: protein_coding
description:
  3-polyprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: HRUBRI_3551
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antiterminator (L factor) transcription regulator protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: HRUBRI_3552
symbol: ribH-2
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: HRUBRI_3553
symbol: ribAB
gene_biotype: protein_coding
description:
  Bifunctional GTP cyclohydrolase II/3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: HRUBRI_3554
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: HRUBRI_3575
symbol: ALU90732.1
gene_biotype: protein_coding
description:
  Acetate permease ActP (cation/acetate symporter); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: HRUBRI_3583
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: HRUBRI_3584
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: HRUBRI_3585
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: HRUBRI_3586
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor protein; Participates in both transcription termination and antitermination.


ensembl_gene_id: HRUBRI_3587
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation factor rimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: HRUBRI_3589
symbol: ALU90746.1
gene_biotype: protein_coding
description:
  Transcription regulator protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: HRUBRI_3592
symbol: sirA
gene_biotype: protein_coding
description:
  Regulator of disulfide bond formation redox protein; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: HRUBRI_3594
symbol: alaS
gene_biotype: protein_coding
description:
  Alanyl-tRNA synthetase protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: HRUBRI_3616
symbol: narG
gene_biotype: protein_coding
description:
  Respiratory nitrate reductase subunit alpha; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HRUBRI_3621
symbol: moaA-2
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis enzyme A protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: HRUBRI_3631
symbol: ribD
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: HRUBRI_3646
symbol: recR
gene_biotype: protein_coding
description:
  Recombinational DNA repair protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: HRUBRI_3648
symbol: ALU90805.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: HRUBRI_3649
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: HRUBRI_3654
symbol: lapB
gene_biotype: protein_coding
description:
  N-acetylglucosaminyl transferase; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: HRUBRI_3656
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: HRUBRI_3657
symbol: rpsA
gene_biotype: protein_coding
description:
  30s ribosomal subunit S1 protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: HRUBRI_3659
symbol: aroA
gene_biotype: protein_coding
description:
  5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: HRUBRI_3662
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: HRUBRI_3663
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: HRUBRI_3665
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyl transferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: HRUBRI_3679
symbol: ALU90836.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: HRUBRI_3682
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: HRUBRI_3748
symbol: kdpC
gene_biotype: protein_coding
description:
  K+ transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: HRUBRI_3749
symbol: kdpB
gene_biotype: protein_coding
description:
  High-affinity K+ transport system ATPase; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: HRUBRI_3750
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: HRUBRI_3762
symbol: upgC
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate ABC transporter ATPase; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: HRUBRI_3763
symbol: ugpE-2
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: HRUBRI_3766
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: HRUBRI_3767
symbol: tpm
gene_biotype: protein_coding
description:
  Thiopurine S-methyltransferase protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: HRUBRI_3772
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: HRUBRI_3773
symbol: yggS
gene_biotype: protein_coding
description:
  Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: HRUBRI_3782
symbol: ALU90939.1
gene_biotype: protein_coding
description:
  TRAP-type C4-dicarboxylate transport system, dctQ-M fusion permease, large permease component protein.


ensembl_gene_id: HRUBRI_3786
symbol: dctA-2
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: HRUBRI_3794
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate synthase protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: HRUBRI_3795
symbol: ispA
gene_biotype: protein_coding
description:
  Geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: HRUBRI_3796
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: HRUBRI_3809
symbol: argC-2
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: HRUBRI_3811
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal L13 protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: HRUBRI_3813
symbol: ubiF
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: HRUBRI_3814
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.


ensembl_gene_id: HRUBRI_3823
symbol: ALU90980.1
gene_biotype: protein_coding
description:
  D-2-hydroxyacid dehydrogenase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HRUBRI_3827
symbol: ALU90984.1
gene_biotype: protein_coding
description:
  Molybdopterin oxido-reductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HRUBRI_3845
symbol: ALU91002.1
gene_biotype: protein_coding
description:
  Lipid A 3-O-deacylase protein (PagL); Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.


ensembl_gene_id: HRUBRI_3857
symbol: gph-3
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase protein; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: HRUBRI_3858
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high  [...]


ensembl_gene_id: HRUBRI_3860
symbol: trpD-2
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: HRUBRI_3863
symbol: ubiB
gene_biotype: protein_coding
description:
  2-polyprenylphenol 6-hydroxylase protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: HRUBRI_3866
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: HRUBRI_3871
symbol: ilvA-5
gene_biotype: protein_coding
description:
  Threonine dehydratase protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: HRUBRI_3872
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: HRUBRI_3873
symbol: ALU91025.1
gene_biotype: protein_coding
description:
  Antimicrobial peptide resistance and lipid A acylation protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.


ensembl_gene_id: HRUBRI_3874
symbol: ptsN
gene_biotype: protein_coding
description:
  Nitrogen PTS system EIIA component; Nitrogen regulatory IIA (Enzyme IIA-NTR) (Phosphotransferase enzyme II, A component) transcription regulator protein.


ensembl_gene_id: HRUBRI_3875
symbol: ptsK
gene_biotype: protein_coding
description:
  Hpr kinase/phosphorylase protein; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).


ensembl_gene_id: HRUBRI_3878
symbol: mutM
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: HRUBRI_3880
symbol: lolB
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein lolB precursor lipoprotein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: HRUBRI_3881
symbol: ipk
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2C-methyl-D-erythritol kinase protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: HRUBRI_3883
symbol: prsA
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: HRUBRI_3884
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: HRUBRI_3894
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase protein; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: HRUBRI_3896
symbol: mdoG-2
gene_biotype: protein_coding
description:
  Periplasmic glucans biosynthesis protein; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: HRUBRI_3907
symbol: ssb
gene_biotype: protein_coding
description:
  Transposase; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: HRUBRI_3910
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ATPase subunit protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: HRUBRI_3918
symbol: lptA
gene_biotype: protein_coding
description:
  Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.


ensembl_gene_id: HRUBRI_3920
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: HRUBRI_3923
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: HRUBRI_3960
symbol: ALU91110.1
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase/carnithine racemase protein; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: HRUBRI_3963
symbol: ALU91113.1
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase type II protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HRUBRI_4009
symbol: petB
gene_biotype: protein_coding
description:
  Cytochrome b subunit protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: HRUBRI_4010
symbol: petA
gene_biotype: protein_coding
description:
  Transmembrane ubiquinol-cytochrome C reductase (Iron-sulfur subunit) oxidoreductase protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: HRUBRI_4011
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: HRUBRI_4015
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: HRUBRI_4016
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: HRUBRI_4017
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: HRUBRI_4020
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: HRUBRI_4021
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol-phosphate synthase protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: HRUBRI_4023
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase (IGPS) protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: HRUBRI_4025
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase 1 protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: HRUBRI_4026
symbol: ALU91175.1
gene_biotype: protein_coding
description:
  DNA-methyltransferase (DNA-modification methylase) protein; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: HRUBRI_4027
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase oxidoreductase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: HRUBRI_4028
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: HRUBRI_4029
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: HRUBRI_4039
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: HRUBRI_4043
symbol: accB
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: HRUBRI_4052
symbol: livGM
gene_biotype: protein_coding
description:
  ABC-type branched-chain amino acid transport system, composite ATP-binding/permease components protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_4066
symbol: paaK-2
gene_biotype: protein_coding
description:
  phenylacetyl-CoA-ligase protein; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: HRUBRI_4073
symbol: kdtB
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase (pantetheine-Phosphate adenylyltransferase) protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: HRUBRI_4078
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle GTPase involved in cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: HRUBRI_4080
symbol: ftsX
gene_biotype: protein_coding
description:
  Cell division (FtsX) protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: HRUBRI_4082
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma-32 factor protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: HRUBRI_4084
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase (heme O synthase) transmembrane protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: HRUBRI_4093
symbol: coxA
gene_biotype: protein_coding
description:
  Cytochrome c oxidase polypeptide I (cytochrome aa3 subunit 1) transmembrane protein; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: HRUBRI_4094
symbol: coxB
gene_biotype: protein_coding
description:
  Cytochrome c oxidase polypeptide II precursor (cytochrome aa3 subunit 2) protein; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: HRUBRI_4096
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: HRUBRI_4098
symbol: cspR
gene_biotype: protein_coding
description:
  rRNA methyltransferase protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: HRUBRI_4100
symbol: ALU91249.1
gene_biotype: protein_coding
description:
  ABC-type transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_4105
symbol: ALU91254.1
gene_biotype: protein_coding
description:
  Nucleotidyl transferase protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.


ensembl_gene_id: HRUBRI_4111
symbol: queC
gene_biotype: protein_coding
description:
  PP-loop superfamily ATPase protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: HRUBRI_4119
symbol: aroBK
gene_biotype: protein_coding
description:
  Bifunctional 3-dehydroquinate synthase/shikimate kinase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: HRUBRI_4120
symbol: dgt
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase protein; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: HRUBRI_4123
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: HRUBRI_4124
symbol: dsbC
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: HRUBRI_4158
symbol: cheD-6
gene_biotype: protein_coding
description:
  Chemoreceptor glutamine deamidase protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: HRUBRI_4180
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase protein; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: HRUBRI_4191
symbol: ALU91338.1
gene_biotype: protein_coding
description:
  ABC-type transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_4194
symbol: minC
gene_biotype: protein_coding
description:
  Septum formation inhibitor protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: HRUBRI_4196
symbol: minE
gene_biotype: protein_coding
description:
  Septum formation topological specificity factor protein; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: HRUBRI_4198
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: HRUBRI_4199
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: HRUBRI_4200
symbol: dsbB
gene_biotype: protein_coding
description:
  Transmembrane disulfide bond formation B oxidoreductase protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: HRUBRI_4201
symbol: hemK-3
gene_biotype: protein_coding
description:
  Polypeptide chain release factors methylase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: HRUBRI_4205
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: HRUBRI_4210
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: HRUBRI_4212
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosylhomocysteinase protein; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: HRUBRI_4213
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: HRUBRI_4216
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: HRUBRI_4220
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific integrase/recombinase protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: HRUBRI_4224
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: HRUBRI_4226
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: HRUBRI_4233
symbol: ahpC
gene_biotype: protein_coding
description:
  Alkylhydroperoxide reductase subunit C protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: HRUBRI_4235
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase protein; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: HRUBRI_4242
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep protein; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: HRUBRI_4243
symbol: hisJ
gene_biotype: protein_coding
description:
  ABC-type amino acid transport/signal transduction systems, periplasmic component/domain protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HRUBRI_4247
symbol: dinP
gene_biotype: protein_coding
description:
  DNA polymerase IV protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: HRUBRI_4248
symbol: dnaE-2
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: HRUBRI_4253
symbol: rdgC
gene_biotype: protein_coding
description:
  DNA recombination-dependent growth factor C (RdgC)protein; May be involved in recombination; Belongs to the RdgC family.


ensembl_gene_id: HRUBRI_4256
symbol: fusA-2
gene_biotype: protein_coding
description:
  Translation elongation factor (EF-G) protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family [...]


ensembl_gene_id: HRUBRI_4260
symbol: ALU91406.1
gene_biotype: protein_coding
description:
  Membrane bound O-acyl transferase MBOAT family protein; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: HRUBRI_4261
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE family protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: HRUBRI_4262
symbol: yidC
gene_biotype: protein_coding
description:
  Inner-membrane transmembrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: HRUBRI_4263
symbol: ALU91409.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: HRUBRI_4264
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: HRUBRI_4277
symbol: metH
gene_biotype: protein_coding
description:
  Methionine synthase I, cobalamin-binding domain-containing protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: HRUBRI_4279
symbol: fmt-2
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: HRUBRI_4284
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N' (replication factor Y)- superfamily II helicase protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: HRUBRI_4285
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: HRUBRI_4289
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, epsilon subunit protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: HRUBRI_4290
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: HRUBRI_4291
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, gamma subunit protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: HRUBRI_4292
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, alpha subunit protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: HRUBRI_4293
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HRUBRI_4294
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, subunit b protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: HRUBRI_4295
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HRUBRI_4296
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1-type ATP synthase, subunit a protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: HRUBRI_4300
symbol: rfbB
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase protein; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: HRUBRI_4301
symbol: rmlA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase - dTDP-glucose pyrophosphorylase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: HRUBRI_4302
symbol: rfbC
gene_biotype: protein_coding
description:
  dTDP-6-deoxy-D-glucose-3,5 epimerase protein; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: HRUBRI_4303
symbol: rmlD
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: HRUBRI_4323
symbol: rfaE-2
gene_biotype: protein_coding
description:
  ADP-heptose synthase / D-glycero-beta-D-manno-heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: HRUBRI_4332
symbol: kefC
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system transmembrane protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: HRUBRI_4344
symbol: ttcA
gene_biotype: protein_coding
description:
  Cell cycle control ATPase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: HRUBRI_4347
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: HRUBRI_4349
symbol: glmS
gene_biotype: protein_coding
description:
  L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: HRUBRI_4386
symbol: ALU91531.1
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: HRUBRI_4401
symbol: acrB-3
gene_biotype: protein_coding
description:
  Acriflavin resistance transmembrane protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: HRUBRI_4402
symbol: ALU91547.1
gene_biotype: protein_coding
description:
  Acriflavin resistance lipoprotein A; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_4407
symbol: czcB
gene_biotype: protein_coding
description:
  Cobalt-zinc-cadmium resistance cation efflux system transmembrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_4423
symbol: maiA
gene_biotype: protein_coding
description:
  Maleate cis-trans isomerase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.


ensembl_gene_id: HRUBRI_4446
symbol: xylG
gene_biotype: protein_coding
description:
  ABC-type D-xylose transport system, ATPase component protein; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.


ensembl_gene_id: HRUBRI_4447
symbol: xylH
gene_biotype: protein_coding
description:
  ABC-type D-xylose transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_4473
symbol: ALU91618.1
gene_biotype: protein_coding
description:
  Low temperature-induced protein; DPS protein, ferritin-like diiron-binding domain protein; Belongs to the Dps family.


ensembl_gene_id: HRUBRI_4497
symbol: dctA-3
gene_biotype: protein_coding
description:
  C4-dicarboxylate transport transmembrane protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: HRUBRI_4506
symbol: metR
gene_biotype: protein_coding
description:
  MetE/MetH family transcription regulator protein; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HRUBRI_4507
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: HRUBRI_4519
symbol: nadE-2
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: HRUBRI_4520
symbol: pncB-2
gene_biotype: protein_coding
description:
  Nicotinic acid phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: HRUBRI_4553
symbol: ALU91698.1
gene_biotype: protein_coding
description:
  Efflux transport, RND family, MFP subunit protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HRUBRI_4566
symbol: ALU91711.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HRUBRI_4583
symbol: ALU91728.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter ATP-binding protein/permease; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_4597
symbol: ALU91742.1
gene_biotype: protein_coding
description:
  Omega-amino acid/pyruvate aminotransferase protein; aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HRUBRI_4605
symbol: ALU91750.1
gene_biotype: protein_coding
description:
  Microcystin LR degradation protein MlrC-like protein; Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC); Belongs to the peptidase M81 family.


ensembl_gene_id: HRUBRI_4609
symbol: gatB
gene_biotype: protein_coding
description:
  Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: HRUBRI_4610
symbol: gatA
gene_biotype: protein_coding
description:
  Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: HRUBRI_4611
symbol: gatC
gene_biotype: protein_coding
description:
  Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: HRUBRI_4615
symbol: mrdA
gene_biotype: protein_coding
description:
  Cell division protein FtsI (peptidoglycan synthetase) protein; Catalyzes cross-linking of the peptidoglycan cell wall.


ensembl_gene_id: HRUBRI_4616
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining (RodA protein) transmembrane protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: HRUBRI_4617
symbol: rlpA
gene_biotype: protein_coding
description:
  Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: HRUBRI_4618
symbol: rsmI
gene_biotype: protein_coding
description:
  Methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: HRUBRI_4621
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: HRUBRI_4625
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: HRUBRI_4630
symbol: def-2
gene_biotype: protein_coding
description:
  Polypeptide deformylase protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: HRUBRI_4653
symbol: hisC-2
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: HRUBRI_4663
symbol: dppD1-2
gene_biotype: protein_coding
description:
  ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HRUBRI_4674
symbol: urtB
gene_biotype: protein_coding
description:
  ABC-type urea transport system, permease component protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: HRUBRI_4678
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory UreD protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: HRUBRI_4682
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory UreE protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: HRUBRI_4683
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory UreF protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: HRUBRI_4684
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory UreG protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: HRUBRI_4700
symbol: flgH-2
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: HRUBRI_4708
symbol: ALU91847.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter/signal transduction system periplasmic protein/domain-containing protein.


ensembl_gene_id: HRUBRI_4720
symbol: mnmC
gene_biotype: protein_coding
description:
  Lipoprotein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: HRUBRI_4723
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: HRUBRI_4728
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoate synthase protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: HRUBRI_4729
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: HRUBRI_4738
symbol: mdoG-3
gene_biotype: protein_coding
description:
  Periplasmic glucan biosynthesis protein; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: HRUBRI_4742
symbol: blc
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein (lipocalin) protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: HRUBRI_4743
symbol: gidB
gene_biotype: protein_coding
description:
  Methyltransferase GidB (glucose inhibited division protein B) protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: HRUBRI_4744
symbol: gidA
gene_biotype: protein_coding
description:
  Glucose inhibited division GidA protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


