# geneInfo

ensembl_gene_id: TH3_00005
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: TH3_00010
symbol: TH3_00010
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: TH3_00015
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: TH3_00020
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: TH3_00070
symbol: TH3_00070
gene_biotype: protein_coding
description:
  COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: TH3_00080
symbol: fcl
gene_biotype: protein_coding
description:
  GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: TH3_00085
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: TH3_00140
symbol: TH3_00140
gene_biotype: protein_coding
description:
  Extra-cytoplasmic solute receptor family protein 22; COG3181 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: TH3_00160
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: TH3_00165
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: TH3_00185
symbol: TH3_00185
gene_biotype: protein_coding
description:
  Arsenate reductase (Arsenical pump modifier); COG1393 Arsenate reductase and related proteins, glutaredoxin family.


ensembl_gene_id: TH3_00195
symbol: TH3_00195
gene_biotype: protein_coding
description:
  Putative regulator of DNA repair (RecX-like) protein; COG2137 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: TH3_00205
symbol: argD
gene_biotype: protein_coding
description:
  Bifunctional acetylornithine aminotransferase and succinyldiaminopimelate; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: TH3_00210
symbol: TH3_00210
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: TH3_00215
symbol: TH3_00215
gene_biotype: protein_coding
description:
  Heat shock protein HSP33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: TH3_00235
symbol: TH3_00235
gene_biotype: protein_coding
description:
  ECF sigma; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_00240
symbol: TH3_00240
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor).


ensembl_gene_id: TH3_00255
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: TH3_00265
symbol: def
gene_biotype: protein_coding
description:
  Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: TH3_00275
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: TH3_00285
symbol: TH3_00285
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TH3_00300
symbol: TH3_00300
gene_biotype: protein_coding
description:
  TRAP transporter 4TM/12TM fusion protein; COG4666 TRAP-type uncharacterized transport system, fused permease components.


ensembl_gene_id: TH3_00310
symbol: TH3_00310
gene_biotype: protein_coding
description:
  31 kDa immunogenic protein; COG2358 TRAP-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: TH3_00315
symbol: TH3_00315
gene_biotype: protein_coding
description:
  Two component Fis family sigma54-specific transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: TH3_00320
symbol: TH3_00320
gene_biotype: protein_coding
description:
  Putative C4-dicarboxylate transport sensor protein dctB; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.


ensembl_gene_id: TH3_00325
symbol: TH3_00325
gene_biotype: protein_coding
description:
  Two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: TH3_00335
symbol: TH3_00335
gene_biotype: protein_coding
description:
  Putative serine kinase/phosphorylase; COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism.


ensembl_gene_id: TH3_00355
symbol: TH3_00355
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: TH3_00360
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: TH3_00405
symbol: TH3_00405
gene_biotype: protein_coding
description:
  Gluconate 2-dehydrogenase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TH3_00430
symbol: TH3_00430
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_00435
symbol: TH3_00435
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter subunit DctP; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: TH3_00440
symbol: TH3_00440
gene_biotype: protein_coding
description:
  Tripartite ATP-independent periplasmic transporter DctQ; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: TH3_00445
symbol: TH3_00445
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter subunit DctM; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: TH3_00450
symbol: TH3_00450
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase substrate binding domain-containing protein; COG0169 Shikimate 5-dehydrogenase.


ensembl_gene_id: TH3_00465
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: TH3_00475
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: TH3_00480
symbol: TH3_00480
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: TH3_00485
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: TH3_00495
symbol: TH3_00495
gene_biotype: protein_coding
description:
  Peroxisomal NADH pyrophosphatase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.


ensembl_gene_id: TH3_00500
symbol: TH3_00500
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: TH3_00540
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: TH3_00545
symbol: dapD
gene_biotype: protein_coding
description:
  COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: TH3_00565
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.


ensembl_gene_id: TH3_00570
symbol: TH3_00570
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase-like FMN-binding protein; COG0748 Putative heme iron utilization protein.


ensembl_gene_id: TH3_00580
symbol: TH3_00580
gene_biotype: protein_coding
description:
  CsbD family protein; COG3237 Uncharacterized protein conserved in bacteria; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: TH3_00605
symbol: ubiE
gene_biotype: protein_coding
description:
  2-octaprenyl-6-methoxy-1,4-benzoquinone methylase / demethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: TH3_00610
symbol: TH3_00610
gene_biotype: protein_coding
description:
  Protein kinase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.


ensembl_gene_id: TH3_00630
symbol: gpt
gene_biotype: protein_coding
description:
  Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.


ensembl_gene_id: TH3_00645
symbol: TH3_00645
gene_biotype: protein_coding
description:
  Cation transport family protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: TH3_00655
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: TH3_00665
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: TH3_00695
symbol: TH3_00695
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase dimerization region; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: TH3_00705
symbol: metZ
gene_biotype: protein_coding
description:
  Cystathionine beta-lyase/cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: TH3_00725
symbol: TH3_00725
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: TH3_00740
symbol: TH3_00740
gene_biotype: protein_coding
description:
  Putative Multidrug-efflux transporter (NorM-like) protein; COG0534 Na+-driven multidrug efflux pump.


ensembl_gene_id: TH3_00760
symbol: TH3_00760
gene_biotype: protein_coding
description:
  Ferric iron ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: TH3_00765
symbol: TH3_00765
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4192 Signal transduction histidine kinase regulating phosphoglycerate transport system.


ensembl_gene_id: TH3_00780
symbol: TH3_00780
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: TH3_00785
symbol: TH3_00785
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_00790
symbol: TH3_00790
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: TH3_00815
symbol: TH3_00815
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: TH3_00860
symbol: TH3_00860
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.


ensembl_gene_id: TH3_01005
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: TH3_01010
symbol: ldh
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.


ensembl_gene_id: TH3_01040
symbol: phnC
gene_biotype: protein_coding
description:
  Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: TH3_01050
symbol: TH3_01050
gene_biotype: protein_coding
description:
  Phosphonate ABC transporter inner membrane subunit; COG3639 ABC-type phosphate/phosphonate transport system, permease component.


ensembl_gene_id: TH3_01075
symbol: TH3_01075
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4778 ABC-type phosphonate transport system, ATPase component.


ensembl_gene_id: TH3_01080
symbol: phnK
gene_biotype: protein_coding
description:
  Phosphonate C-P lyase system protein PhnK; COG4107 ABC-type phosphonate transport system, ATPase component.


ensembl_gene_id: TH3_01085
symbol: TH3_01085
gene_biotype: protein_coding
description:
  Carbon-phosphorus lyase complex subunit PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.


ensembl_gene_id: TH3_01090
symbol: TH3_01090
gene_biotype: protein_coding
description:
  Carbon-phosphorus lyase complex subunit PhnI; COG3626 Uncharacterized enzyme of phosphonate metabolism.


ensembl_gene_id: TH3_01095
symbol: TH3_01095
gene_biotype: protein_coding
description:
  Phosphonate C-P lyase system protein PhnH; COG3625 Uncharacterized enzyme of phosphonate metabolism.


ensembl_gene_id: TH3_01100
symbol: TH3_01100
gene_biotype: protein_coding
description:
  Phosphonate C-P lyase system protein PhnG; COG3624 Uncharacterized enzyme of phosphonate metabolism.


ensembl_gene_id: TH3_01120
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: TH3_01125
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: TH3_01135
symbol: TH3_01135
gene_biotype: protein_coding
description:
  TRAP transporter solute receptor, TAXI family protein; COG2358 TRAP-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: TH3_01140
symbol: TH3_01140
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter, fused membrane component DctQM; COG4666 TRAP-type uncharacterized transport system, fused permease components.


ensembl_gene_id: TH3_01185
symbol: TH3_01185
gene_biotype: protein_coding
description:
  Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: TH3_01200
symbol: TH3_01200
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_01220
symbol: TH3_01220
gene_biotype: protein_coding
description:
  Major facilitator superfamily transporter; COG2211 Na+/melibiose symporter and related transporters.


ensembl_gene_id: TH3_01235
symbol: TH3_01235
gene_biotype: protein_coding
description:
  NAD(P)-binding short-chain dehydrogenase/reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_01260
symbol: TH3_01260
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: TH3_01280
symbol: TH3_01280
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: TH3_01285
symbol: TH3_01285
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: TH3_01295
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: TH3_01300
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: TH3_01305
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.


ensembl_gene_id: TH3_01340
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: TH3_01380
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: TH3_01390
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: TH3_01395
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: TH3_01415
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: TH3_01420
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: TH3_01425
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: TH3_01430
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: TH3_01435
symbol: atpC
gene_biotype: protein_coding
description:
  F-type H+-transporting ATPase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: TH3_01455
symbol: TH3_01455
gene_biotype: protein_coding
description:
  Cation efflux protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: TH3_01460
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: TH3_01475
symbol: TH3_01475
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: TH3_01490
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: TH3_01515
symbol: TH3_01515
gene_biotype: protein_coding
description:
  RND family efflux system membrane fusion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TH3_01520
symbol: TH3_01520
gene_biotype: protein_coding
description:
  RND family efflux transporter; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TH3_01555
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: TH3_01575
symbol: TH3_01575
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_01580
symbol: TH3_01580
gene_biotype: protein_coding
description:
  ATP-binding protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_01585
symbol: TH3_01585
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: TH3_01605
symbol: TH3_01605
gene_biotype: protein_coding
description:
  Sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_01650
symbol: TH3_01650
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: TH3_01655
symbol: TH3_01655
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: TH3_01665
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: TH3_01670
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: TH3_01680
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: TH3_01685
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: TH3_01690
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: TH3_01695
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: TH3_01705
symbol: ffh
gene_biotype: protein_coding
description:
  GTPase of the signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual co [...]


ensembl_gene_id: TH3_01710
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: TH3_01715
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: TH3_01720
symbol: TH3_01720
gene_biotype: protein_coding
description:
  CRP/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_01725
symbol: TH3_01725
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome oxidase maturation protein; COG3197 Uncharacterized protein, possibly involved in nitrogen fixation.


ensembl_gene_id: TH3_01745
symbol: TH3_01745
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome c oxidase subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: TH3_01760
symbol: TH3_01760
gene_biotype: protein_coding
description:
  COG3278 Cbb3-type cytochrome oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: TH3_01770
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: TH3_01805
symbol: TH3_01805
gene_biotype: protein_coding
description:
  Trans-aconitate methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.


ensembl_gene_id: TH3_01815
symbol: rppH
gene_biotype: protein_coding
description:
  (Di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: TH3_01825
symbol: TH3_01825
gene_biotype: protein_coding
description:
  C-terminal processing peptidase S41A; COG0793 Periplasmic protease; Belongs to the peptidase S41A family.


ensembl_gene_id: TH3_01855
symbol: rlmH
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: TH3_01860
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: TH3_01865
symbol: nadD
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide adenylyltransferase (NadD-like) protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: TH3_01870
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: TH3_01875
symbol: TH3_01875
gene_biotype: protein_coding
description:
  COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components.


ensembl_gene_id: TH3_01925
symbol: TH3_01925
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: TH3_01935
symbol: TH3_01935
gene_biotype: protein_coding
description:
  COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_01940
symbol: TH3_01940
gene_biotype: protein_coding
description:
  COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_01945
symbol: TH3_01945
gene_biotype: protein_coding
description:
  Ribose import ATP-binding protein RbsA; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: TH3_01950
symbol: TH3_01950
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: TH3_01955
symbol: TH3_01955
gene_biotype: protein_coding
description:
  DNA methylase N-4/N-6 domain-containing protein; COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: TH3_01970
symbol: TH3_01970
gene_biotype: protein_coding
description:
  Zn-ribbon-containing, possibly RNA-binding protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: TH3_01980
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: TH3_01995
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: TH3_02000
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: TH3_02005
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: TH3_02010
symbol: atpF-2
gene_biotype: protein_coding
description:
  ATP synthase B chain precursor; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: TH3_02035
symbol: TH3_02035
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: TH3_02050
symbol: TH3_02050
gene_biotype: protein_coding
description:
  Putative NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: TH3_02060
symbol: TH3_02060
gene_biotype: protein_coding
description:
  COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: TH3_02080
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD subunit; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: TH3_02095
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: TH3_02100
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: TH3_02135
symbol: TH3_02135
gene_biotype: protein_coding
description:
  BolA family protein; COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.


ensembl_gene_id: TH3_02150
symbol: TH3_02150
gene_biotype: protein_coding
description:
  Cobalt chelatase large subunit; COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase).


ensembl_gene_id: TH3_02155
symbol: TH3_02155
gene_biotype: protein_coding
description:
  COG0008 Glutamyl- and glutaminyl-tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: TH3_02165
symbol: TH3_02165
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_02170
symbol: TH3_02170
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: TH3_02225
symbol: TH3_02225
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase (NADP+); COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: TH3_02245
symbol: TH3_02245
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_02250
symbol: TH3_02250
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_02255
symbol: TH3_02255
gene_biotype: protein_coding
description:
  Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: TH3_02260
symbol: TH3_02260
gene_biotype: protein_coding
description:
  Amino acid/amide ABC transporter substrate-binding protein, HAAT family; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: TH3_02265
symbol: TH3_02265
gene_biotype: protein_coding
description:
  Two component sigma-54-specific Fis family transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: TH3_02285
symbol: TH3_02285
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter subunit DctQ; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: TH3_02330
symbol: TH3_02330
gene_biotype: protein_coding
description:
  Iron-chelate uptake ABC transporter, FeCT family, periplasmic iron-chelate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: TH3_02335
symbol: ade
gene_biotype: protein_coding
description:
  COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: TH3_02350
symbol: TH3_02350
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: TH3_02355
symbol: TH3_02355
gene_biotype: protein_coding
description:
  Transmembrane component of ABC transporter; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: TH3_02360
symbol: TH3_02360
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: TH3_02375
symbol: TH3_02375
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: TH3_02390
symbol: TH3_02390
gene_biotype: protein_coding
description:
  Isoquinoline 1-oxidoreductase subunit beta; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: TH3_02395
symbol: TH3_02395
gene_biotype: protein_coding
description:
  (2Fe-2S)-binding domain-containing protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: TH3_02415
symbol: TH3_02415
gene_biotype: protein_coding
description:
  Trap dicarboxylate transporter, dctm subunit; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: TH3_02425
symbol: TH3_02425
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter- DctP subunit; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: TH3_02440
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: TH3_02445
symbol: TH3_02445
gene_biotype: protein_coding
description:
  Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: TH3_02470
symbol: TH3_02470
gene_biotype: protein_coding
description:
  Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.


ensembl_gene_id: TH3_02485
symbol: TH3_02485
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: TH3_02505
symbol: TH3_02505
gene_biotype: protein_coding
description:
  Putative Periplasmic binding proteins and sugar binding domain of the LacI family; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_02525
symbol: TH3_02525
gene_biotype: protein_coding
description:
  Glycolate reductase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TH3_02530
symbol: TH3_02530
gene_biotype: protein_coding
description:
  TRAP-T family transporter periplasmic binding protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: TH3_02535
symbol: TH3_02535
gene_biotype: protein_coding
description:
  Tripartite ATP-independent periplasmic transporter, DctQ component; COG4665 TRAP-type mannitol/chloroaromatic compound transport system, small permease component.


ensembl_gene_id: TH3_02540
symbol: TH3_02540
gene_biotype: protein_coding
description:
  TRAP C4-dicarboxylate transporter permease DctM; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.


ensembl_gene_id: TH3_02595
symbol: TH3_02595
gene_biotype: protein_coding
description:
  Ectoine utilization protein EutC; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.


ensembl_gene_id: TH3_02615
symbol: TH3_02615
gene_biotype: protein_coding
description:
  Ectoin/5-hydroxyectoin TRAP transporter small integral membrane protein; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: TH3_02620
symbol: TH3_02620
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: TH3_02630
symbol: TH3_02630
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_02660
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: TH3_02675
symbol: TH3_02675
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase, zinc-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: TH3_02690
symbol: TH3_02690
gene_biotype: protein_coding
description:
  Type 1 secretion target domain-containing protein; COG2931 RTX toxins and related Ca2+-binding proteins.


ensembl_gene_id: TH3_02730
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: TH3_02745
symbol: TH3_02745
gene_biotype: protein_coding
description:
  PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: TH3_02750
symbol: TH3_02750
gene_biotype: protein_coding
description:
  COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: TH3_02765
symbol: TH3_02765
gene_biotype: protein_coding
description:
  2-oxo/hydroxy acid reductase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TH3_02810
symbol: TH3_02810
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_02840
symbol: TH3_02840
gene_biotype: protein_coding
description:
  COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).


ensembl_gene_id: TH3_02845
symbol: TH3_02845
gene_biotype: protein_coding
description:
  ABC-type protease/lipase transport system, ATPase and permease components; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: TH3_02850
symbol: TH3_02850
gene_biotype: protein_coding
description:
  COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: TH3_02870
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: TH3_02875
symbol: TH3_02875
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: TH3_02880
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: TH3_02885
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: TH3_02890
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: TH3_02905
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: TH3_02935
symbol: TH3_02935
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_02945
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: TH3_02990
symbol: TH3_02990
gene_biotype: protein_coding
description:
  Putative gamma-glutamyl-gamma-aminobutyrate hydrolase; COG2071 Predicted glutamine amidotransferases.


ensembl_gene_id: TH3_02995
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: TH3_03000
symbol: mdoD
gene_biotype: protein_coding
description:
  Glucan biosynthesis protein D; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: TH3_03015
symbol: TH3_03015
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: TH3_03020
symbol: TH3_03020
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: TH3_03025
symbol: TH3_03025
gene_biotype: protein_coding
description:
  Iron ABC transporter substrate binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: TH3_03030
symbol: TH3_03030
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TH3_03035
symbol: TH3_03035
gene_biotype: protein_coding
description:
  Iron ABC transporter; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: TH3_03045
symbol: xseA
gene_biotype: protein_coding
description:
  Exonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: TH3_03075
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: TH3_03080
symbol: TH3_03080
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: TH3_03115
symbol: TH3_03115
gene_biotype: protein_coding
description:
  Putative Zn-dependent protease, pmbA-like protein; COG0312 Predicted Zn-dependent proteases and their inactivated homologs.


ensembl_gene_id: TH3_03125
symbol: TH3_03125
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid.


ensembl_gene_id: TH3_03135
symbol: TH3_03135
gene_biotype: protein_coding
description:
  COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: TH3_03160
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate-octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: TH3_03165
symbol: TH3_03165
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: TH3_03170
symbol: TH3_03170
gene_biotype: protein_coding
description:
  Gamma-glutamylcysteine synthetase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.


ensembl_gene_id: TH3_03180
symbol: glpD
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: TH3_03190
symbol: TH3_03190
gene_biotype: protein_coding
description:
  ABC transporter permease; COG3639 ABC-type phosphate/phosphonate transport system, permease component.


ensembl_gene_id: TH3_03195
symbol: phnC-2
gene_biotype: protein_coding
description:
  Phosphonate ABC transporter ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: TH3_03205
symbol: TH3_03205
gene_biotype: protein_coding
description:
  Putative glycerol-3-phosphate regulon repressor; COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: TH3_03210
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: TH3_03245
symbol: TH3_03245
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: TH3_03255
symbol: dppF
gene_biotype: protein_coding
description:
  Dipeptide transporter ATP-binding subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_03260
symbol: dppD
gene_biotype: protein_coding
description:
  Dipeptide transporter ATP-binding subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_03265
symbol: TH3_03265
gene_biotype: protein_coding
description:
  Protein DppC2; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_03270
symbol: TH3_03270
gene_biotype: protein_coding
description:
  Nickel-transporting ATPase; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_03275
symbol: TH3_03275
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: TH3_03280
symbol: TH3_03280
gene_biotype: protein_coding
description:
  Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: TH3_03305
symbol: TH3_03305
gene_biotype: protein_coding
description:
  Peptidase U62 modulator of DNA gyrase; COG0312 Predicted Zn-dependent proteases and their inactivated homologs.


ensembl_gene_id: TH3_03320
symbol: ctaA
gene_biotype: protein_coding
description:
  Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.


ensembl_gene_id: TH3_03330
symbol: TH3_03330
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: TH3_03390
symbol: acdS
gene_biotype: protein_coding
description:
  1-aminocyclopropane-1-carboxylate deaminase; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source; Belongs to the ACC deaminase/D-cysteine desulfhydrase family.


ensembl_gene_id: TH3_03395
symbol: TH3_03395
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter subunit DctM; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.


ensembl_gene_id: TH3_03405
symbol: TH3_03405
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter subunit DctP; COG4663 TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component.


ensembl_gene_id: TH3_03440
symbol: TH3_03440
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.


ensembl_gene_id: TH3_03465
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: TH3_03470
symbol: gltX-2
gene_biotype: protein_coding
description:
  glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: TH3_03480
symbol: TH3_03480
gene_biotype: protein_coding
description:
  Carboxymuconolactone decarboxylase-like protein; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


ensembl_gene_id: TH3_03490
symbol: TH3_03490
gene_biotype: protein_coding
description:
  NADP-dependent oxidoreductase domain-containing protein; COG0656 Aldo/keto reductases, related to diketogulonate reductase.


ensembl_gene_id: TH3_03505
symbol: TH3_03505
gene_biotype: protein_coding
description:
  DSBA oxidoreductase; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: TH3_03515
symbol: TH3_03515
gene_biotype: protein_coding
description:
  Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: TH3_03525
symbol: TH3_03525
gene_biotype: protein_coding
description:
  Agmatine ureohydrolase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: TH3_03530
symbol: TH3_03530
gene_biotype: protein_coding
description:
  Polyamine-transporting ATPase; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: TH3_03540
symbol: TH3_03540
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: TH3_03555
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: TH3_03580
symbol: TH3_03580
gene_biotype: protein_coding
description:
  BolA-like protein; COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.


ensembl_gene_id: TH3_03595
symbol: TH3_03595
gene_biotype: protein_coding
description:
  Monooxygenase family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: TH3_03600
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: TH3_03620
symbol: TH3_03620
gene_biotype: protein_coding
description:
  CheA signal transduction histidine kinase; COG0643 Chemotaxis protein histidine kinase and related kinases.


ensembl_gene_id: TH3_03635
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis-specific protein-glutamate methyltransferase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: TH3_03645
symbol: TH3_03645
gene_biotype: protein_coding
description:
  Two-component cell cycle transcriptional regulator ctrA; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: TH3_03720
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: TH3_03725
symbol: TH3_03725
gene_biotype: protein_coding
description:
  Flagellar genes transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: TH3_03735
symbol: TH3_03735
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: TH3_03745
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: TH3_03755
symbol: TH3_03755
gene_biotype: protein_coding
description:
  Flagellar basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: TH3_03770
symbol: TH3_03770
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2 (FliD, filament cap protein) precursor; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: TH3_03775
symbol: TH3_03775
gene_biotype: protein_coding
description:
  Flagellin domain-containing protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: TH3_03780
symbol: TH3_03780
gene_biotype: protein_coding
description:
  Flagellin, C-terminal:flagellin, N-terminal; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: TH3_03785
symbol: TH3_03785
gene_biotype: protein_coding
description:
  Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: TH3_03805
symbol: TH3_03805
gene_biotype: protein_coding
description:
  Flagellar assembly factor fliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. Belongs to the FliW family.


ensembl_gene_id: TH3_03815
symbol: TH3_03815
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1256 Flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: TH3_03830
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: TH3_03840
symbol: dksA
gene_biotype: protein_coding
description:
  TraR/DksA family transcriptional regulator; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: TH3_03845
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: TH3_03865
symbol: TH3_03865
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: TH3_03870
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: TH3_03925
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: TH3_03940
symbol: TH3_03940
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.


ensembl_gene_id: TH3_03945
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.


ensembl_gene_id: TH3_03950
symbol: TH3_03950
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: TH3_03965
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: TH3_03970
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: TH3_03975
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: TH3_04020
symbol: TH3_04020
gene_biotype: protein_coding
description:
  CopG family transcriptional regulator NikR; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.


ensembl_gene_id: TH3_04025
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: TH3_04065
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: TH3_04170
symbol: TH3_04170
gene_biotype: protein_coding
description:
  COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: TH3_04195
symbol: TH3_04195
gene_biotype: protein_coding
description:
  Multidrug resistance efflux pump (EmrB-like) protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: TH3_04205
symbol: TH3_04205
gene_biotype: protein_coding
description:
  Translation-associated GTPase; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: TH3_04220
symbol: TH3_04220
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_04225
symbol: TH3_04225
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_04255
symbol: TH3_04255
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: TH3_04270
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: TH3_04275
symbol: TH3_04275
gene_biotype: protein_coding
description:
  COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: TH3_04290
symbol: TH3_04290
gene_biotype: protein_coding
description:
  AcrB protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: TH3_04295
symbol: TH3_04295
gene_biotype: protein_coding
description:
  RND family efflux transporter MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TH3_04330
symbol: queE
gene_biotype: protein_coding
description:
  Radical activating protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: TH3_04340
symbol: queC
gene_biotype: protein_coding
description:
  Succinoglycan biosynthesis regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: TH3_04360
symbol: TH3_04360
gene_biotype: protein_coding
description:
  Superoxide dismutase, copper/zinc binding protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: TH3_04385
symbol: TH3_04385
gene_biotype: protein_coding
description:
  COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: TH3_04430
symbol: TH3_04430
gene_biotype: protein_coding
description:
  N-acetylmannosaminyltransferase; COG1922 Teichoic acid biosynthesis proteins; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: TH3_04455
symbol: TH3_04455
gene_biotype: protein_coding
description:
  Antitoxin of a toxin/antitoxin system, phd-like protein; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: TH3_04475
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: TH3_04505
symbol: TH3_04505
gene_biotype: protein_coding
description:
  2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: TH3_04520
symbol: TH3_04520
gene_biotype: protein_coding
description:
  Crp/Fnr family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_04550
symbol: TH3_04550
gene_biotype: protein_coding
description:
  Sterol 3-beta-glucosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: TH3_04590
symbol: TH3_04590
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: TH3_04610
symbol: TH3_04610
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily.


ensembl_gene_id: TH3_04620
symbol: TH3_04620
gene_biotype: protein_coding
description:
  Putative Methyl-accepting chemotaxis sensory transducer; COG0840 Methyl-accepting chemotaxis protein.


ensembl_gene_id: TH3_04625
symbol: TH3_04625
gene_biotype: protein_coding
description:
  Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: TH3_04650
symbol: TH3_04650
gene_biotype: protein_coding
description:
  Aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: TH3_04660
symbol: TH3_04660
gene_biotype: protein_coding
description:
  ABC transporter iron-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: TH3_04670
symbol: fbpC
gene_biotype: protein_coding
description:
  iron(III) ABC transporter; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: TH3_04675
symbol: TH3_04675
gene_biotype: protein_coding
description:
  Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: TH3_04685
symbol: TH3_04685
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2932 Predicted transcriptional regulator; Belongs to the peptidase S24 family.


ensembl_gene_id: TH3_04710
symbol: TH3_04710
gene_biotype: protein_coding
description:
  HicB family protein; COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters.


ensembl_gene_id: TH3_04895
symbol: TH3_04895
gene_biotype: protein_coding
description:
  NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: TH3_04930
symbol: TH3_04930
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: TH3_04940
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: TH3_04945
symbol: TH3_04945
gene_biotype: protein_coding
description:
  Putative sugar phosphatase (HAD superfamily) protein; COG0647 Predicted sugar phosphatases of the HAD superfamily.


ensembl_gene_id: TH3_04970
symbol: TH3_04970
gene_biotype: protein_coding
description:
  Nickel-binding periplasmic protein NikA; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: TH3_04975
symbol: TH3_04975
gene_biotype: protein_coding
description:
  ABC transporter inner membrane protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_04980
symbol: TH3_04980
gene_biotype: protein_coding
description:
  ABC transporter inner membrane protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_04985
symbol: TH3_04985
gene_biotype: protein_coding
description:
  ABC transporter; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase.


ensembl_gene_id: TH3_04990
symbol: TH3_04990
gene_biotype: protein_coding
description:
  Class IV aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: TH3_04995
symbol: TH3_04995
gene_biotype: protein_coding
description:
  N-hydroxyarylamine O-acetyltransferase; COG2162 Arylamine N-acetyltransferase; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: TH3_05000
symbol: TH3_05000
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: TH3_05005
symbol: TH3_05005
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: TH3_05030
symbol: TH3_05030
gene_biotype: protein_coding
description:
  Sigma-24 (FecI); COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_05060
symbol: TH3_05060
gene_biotype: protein_coding
description:
  Sugar ABC transporter; COG4120 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_05090
symbol: TH3_05090
gene_biotype: protein_coding
description:
  Secretion protein HlyD; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TH3_05120
symbol: nadK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: TH3_05140
symbol: TH3_05140
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase, DEAD/DEAH box family protein; COG0513 Superfamily II DNA and RNA helicases.


ensembl_gene_id: TH3_05155
symbol: TH3_05155
gene_biotype: protein_coding
description:
  COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: TH3_05160
symbol: TH3_05160
gene_biotype: protein_coding
description:
  Glutamine ABC superfamily ATP binding cassette transporter, membrane protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: TH3_05180
symbol: TH3_05180
gene_biotype: protein_coding
description:
  YaiI/YqxD family protein; COG1671 Uncharacterized protein conserved in bacteria; Belongs to the UPF0178 family.


ensembl_gene_id: TH3_05200
symbol: TH3_05200
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG2130 Putative NADP-dependent oxidoreductases.


ensembl_gene_id: TH3_05205
symbol: TH3_05205
gene_biotype: protein_coding
description:
  TspO and MBR like protein; COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog).


ensembl_gene_id: TH3_05240
symbol: TH3_05240
gene_biotype: protein_coding
description:
  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: TH3_05275
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: TH3_05280
symbol: TH3_05280
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: TH3_05285
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: TH3_05295
symbol: TH3_05295
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: TH3_05305
symbol: TH3_05305
gene_biotype: protein_coding
description:
  Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer; COG0840 Methyl-accepting chemotaxis protein.


ensembl_gene_id: TH3_05360
symbol: TH3_05360
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: TH3_05365
symbol: TH3_05365
gene_biotype: protein_coding
description:
  Regulatory protein LuxO; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: TH3_05370
symbol: TH3_05370
gene_biotype: protein_coding
description:
  Cobalamin biosynthetic protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: TH3_05400
symbol: TH3_05400
gene_biotype: protein_coding
description:
  Sugar ABC transporter substrate-binding protein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_05410
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: TH3_05440
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: TH3_05470
symbol: TH3_05470
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: TH3_05475
symbol: TH3_05475
gene_biotype: protein_coding
description:
  Ectoine hydroxylase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: TH3_05485
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: TH3_05500
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: TH3_05505
symbol: TH3_05505
gene_biotype: protein_coding
description:
  COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: TH3_05520
symbol: TH3_05520
gene_biotype: protein_coding
description:
  Alkylphosphonate utilization operon protein PhnA; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: TH3_05530
symbol: TH3_05530
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_05585
symbol: TH3_05585
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: TH3_05645
symbol: TH3_05645
gene_biotype: protein_coding
description:
  Lactose transport ATP-binding protein LacK; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_05650
symbol: TH3_05650
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_05675
symbol: gabD
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase I; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: TH3_05690
symbol: TH3_05690
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_05715
symbol: TH3_05715
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: TH3_05730
symbol: TH3_05730
gene_biotype: protein_coding
description:
  COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_05735
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: TH3_05745
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: TH3_05795
symbol: TH3_05795
gene_biotype: protein_coding
description:
  High-affinity nickel-transporter; COG2215 ABC-type uncharacterized transport system, permease component; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: TH3_05805
symbol: TH3_05805
gene_biotype: protein_coding
description:
  Periplasmic solute binding protein; COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin.


ensembl_gene_id: TH3_05825
symbol: TH3_05825
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: TH3_05830
symbol: TH3_05830
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_05835
symbol: TH3_05835
gene_biotype: protein_coding
description:
  Oligopeptide transporter permease; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_05870
symbol: TH3_05870
gene_biotype: protein_coding
description:
  C4-dicarboxylate ABC transporter substrate-binding protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: TH3_05875
symbol: TH3_05875
gene_biotype: protein_coding
description:
  Tripartite ATP-independent periplasmic transporter subunit DctQ; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: TH3_05915
symbol: TH3_05915
gene_biotype: protein_coding
description:
  COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: TH3_05920
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: TH3_05925
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: TH3_05930
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: TH3_05935
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: TH3_05940
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: TH3_05945
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: TH3_05955
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: TH3_05960
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: TH3_05970
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: TH3_05975
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: TH3_05980
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: TH3_05990
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: TH3_05995
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: TH3_06005
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: TH3_06010
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: TH3_06015
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: TH3_06020
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: TH3_06025
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: TH3_06030
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: TH3_06040
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: TH3_06045
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: TH3_06050
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: TH3_06055
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: TH3_06060
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: TH3_06065
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: TH3_06070
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: TH3_06075
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: TH3_06080
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: TH3_06090
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: TH3_06095
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: TH3_06100
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: TH3_06105
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: TH3_06110
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: TH3_06115
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: TH3_06125
symbol: TH3_06125
gene_biotype: protein_coding
description:
  COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: TH3_06140
symbol: TH3_06140
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: TH3_06145
symbol: azoR
gene_biotype: protein_coding
description:
  Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: TH3_06155
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: TH3_06160
symbol: TH3_06160
gene_biotype: protein_coding
description:
  RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: TH3_06190
symbol: TH3_06190
gene_biotype: protein_coding
description:
  Putative aliphatic sulfonates transport systempermease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: TH3_06195
symbol: TH3_06195
gene_biotype: protein_coding
description:
  Putative aliphatic sulfonates transport systemATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: TH3_06200
symbol: TH3_06200
gene_biotype: protein_coding
description:
  Putative periplasmic-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: TH3_06265
symbol: TH3_06265
gene_biotype: protein_coding
description:
  Putative translation factor (Sua5-like) protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: TH3_06275
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: TH3_06280
symbol: ftrA
gene_biotype: protein_coding
description:
  Transcriptional activator FtrA; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: TH3_06290
symbol: TH3_06290
gene_biotype: protein_coding
description:
  GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: TH3_06320
symbol: pepA
gene_biotype: protein_coding
description:
  Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: TH3_06345
symbol: TH3_06345
gene_biotype: protein_coding
description:
  ABC transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.


ensembl_gene_id: TH3_06350
symbol: TH3_06350
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG2011 ABC-type metal ion transport system, permease component.


ensembl_gene_id: TH3_06355
symbol: TH3_06355
gene_biotype: protein_coding
description:
  Lipoprotein YaeC; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: TH3_06440
symbol: ndk
gene_biotype: protein_coding
description:
  Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: TH3_06460
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: TH3_06465
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase.


ensembl_gene_id: TH3_06480
symbol: TH3_06480
gene_biotype: protein_coding
description:
  Chromosomal replication initiator; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family.


ensembl_gene_id: TH3_06490
symbol: rimK
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the RimK family.


ensembl_gene_id: TH3_06500
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: TH3_06530
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: TH3_06540
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: TH3_06575
symbol: xseB
gene_biotype: protein_coding
description:
  Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: TH3_06590
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: TH3_06630
symbol: TH3_06630
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: TH3_06635
symbol: TH3_06635
gene_biotype: protein_coding
description:
  Family 7 extracellular solute-binding protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: TH3_06680
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: TH3_06700
symbol: TH3_06700
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: TH3_06715
symbol: TH3_06715
gene_biotype: protein_coding
description:
  Transporter, small conductance mechanosensitive ion channel (MscS) family protein; COG3264 Small-conductance mechanosensitive channel.


ensembl_gene_id: TH3_06745
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: TH3_06800
symbol: TH3_06800
gene_biotype: protein_coding
description:
  Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_06840
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: TH3_06860
symbol: TH3_06860
gene_biotype: protein_coding
description:
  Bcr/CflA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: TH3_06880
symbol: TH3_06880
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: TH3_06885
symbol: TH3_06885
gene_biotype: protein_coding
description:
  Histidine kinase; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.


ensembl_gene_id: TH3_06935
symbol: TH3_06935
gene_biotype: protein_coding
description:
  COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: TH3_06940
symbol: TH3_06940
gene_biotype: protein_coding
description:
  Histidine triad (HIT) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: TH3_06945
symbol: TH3_06945
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: TH3_06950
symbol: azoR-2
gene_biotype: protein_coding
description:
  ACP phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: TH3_06985
symbol: TH3_06985
gene_biotype: protein_coding
description:
  Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: TH3_07060
symbol: TH3_07060
gene_biotype: protein_coding
description:
  Lysophospholipase; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: TH3_07065
symbol: TH3_07065
gene_biotype: protein_coding
description:
  Myo-inositol-1(or 4)-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: TH3_07070
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: TH3_07075
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: TH3_07090
symbol: TH3_07090
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: TH3_07100
symbol: TH3_07100
gene_biotype: protein_coding
description:
  Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: TH3_07110
symbol: TH3_07110
gene_biotype: protein_coding
description:
  Putative methyl-accepting chemotaxis receptor/sensory transducer; COG0840 Methyl-accepting chemotaxis protein.


ensembl_gene_id: TH3_07125
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: TH3_07130
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: TH3_07135
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: TH3_07145
symbol: tolQ
gene_biotype: protein_coding
description:
  Proton channel of the Tol-Pal system; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: TH3_07160
symbol: tolB
gene_biotype: protein_coding
description:
  Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: TH3_07165
symbol: pal
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein omp16; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: TH3_07175
symbol: cpoB
gene_biotype: protein_coding
description:
  Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: TH3_07180
symbol: tilS
gene_biotype: protein_coding
description:
  ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: TH3_07185
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein FtsH, ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: TH3_07215
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: TH3_07270
symbol: TH3_07270
gene_biotype: protein_coding
description:
  Putative transporter; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: TH3_07275
symbol: TH3_07275
gene_biotype: protein_coding
description:
  Putative transporter; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: TH3_07315
symbol: TH3_07315
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: TH3_07320
symbol: TH3_07320
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: TH3_07325
symbol: potA
gene_biotype: protein_coding
description:
  Putrescine transport ATP-binding protein PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: TH3_07330
symbol: TH3_07330
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: TH3_07345
symbol: TH3_07345
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: TH3_07360
symbol: TH3_07360
gene_biotype: protein_coding
description:
  Phosphinothricin acetyltransferase (PPT N-acetyltransferase); COG1247 Sortase and related acyltransferases.


ensembl_gene_id: TH3_07380
symbol: TH3_07380
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein/permease; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: TH3_07410
symbol: TH3_07410
gene_biotype: protein_coding
description:
  Class III aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_07440
symbol: TH3_07440
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: TH3_07445
symbol: TH3_07445
gene_biotype: protein_coding
description:
  Putative sulfonate/nitrate transport system substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: TH3_07450
symbol: TH3_07450
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: TH3_07455
symbol: TH3_07455
gene_biotype: protein_coding
description:
  Putative LysR-family regulatory protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TH3_07525
symbol: TH3_07525
gene_biotype: protein_coding
description:
  Winged helix family two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: TH3_07540
symbol: vapC
gene_biotype: protein_coding
description:
  Nucleic acid binding protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: TH3_07555
symbol: TH3_07555
gene_biotype: protein_coding
description:
  Family 1 extracellular solute-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: TH3_07560
symbol: TH3_07560
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0555 ABC-type sulfate transport system, permease component.


ensembl_gene_id: TH3_07570
symbol: TH3_07570
gene_biotype: protein_coding
description:
  COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_07575
symbol: cpdA
gene_biotype: protein_coding
description:
  Putative metallophosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: TH3_07585
symbol: TH3_07585
gene_biotype: protein_coding
description:
  Smr family multidrug resistance protein; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: TH3_07605
symbol: TH3_07605
gene_biotype: protein_coding
description:
  Endoribonuclease L-PSP family protein; COG0251 Putative translation initiation inhibitor, yjgF family.


ensembl_gene_id: TH3_07670
symbol: TH3_07670
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: TH3_07680
symbol: TH3_07680
gene_biotype: protein_coding
description:
  COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: TH3_07745
symbol: TH3_07745
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: TH3_07755
symbol: TH3_07755
gene_biotype: protein_coding
description:
  Hydrolase, alpha; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: TH3_07780
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: TH3_07795
symbol: TH3_07795
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain.


ensembl_gene_id: TH3_07800
symbol: TH3_07800
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase/reductase SFR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: TH3_07875
symbol: TH3_07875
gene_biotype: protein_coding
description:
  COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis.


ensembl_gene_id: TH3_07890
symbol: TH3_07890
gene_biotype: protein_coding
description:
  ompA family protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: TH3_07905
symbol: msrQ
gene_biotype: protein_coding
description:
  Ferric reductase domain-containing protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic s [...]


ensembl_gene_id: TH3_07935
symbol: TH3_07935
gene_biotype: protein_coding
description:
  Putative thioesterase; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: TH3_07940
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: TH3_07975
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: TH3_07995
symbol: TH3_07995
gene_biotype: protein_coding
description:
  Family 3 extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: TH3_08015
symbol: TH3_08015
gene_biotype: protein_coding
description:
  NAD-binding 6-phosphogluconate dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: TH3_08075
symbol: TH3_08075
gene_biotype: protein_coding
description:
  Periplasmic substrate binding protein family 3; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: TH3_08085
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: TH3_08135
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: TH3_08165
symbol: TH3_08165
gene_biotype: protein_coding
description:
  N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.


ensembl_gene_id: TH3_08170
symbol: TH3_08170
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: TH3_08175
symbol: TH3_08175
gene_biotype: protein_coding
description:
  ABC transporter, permease component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: TH3_08180
symbol: TH3_08180
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding component; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: TH3_08195
symbol: TH3_08195
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin family outer membrane protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: TH3_08240
symbol: TH3_08240
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: TH3_08250
symbol: TH3_08250
gene_biotype: protein_coding
description:
  Putative CoA transferase family protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: TH3_08325
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: TH3_08330
symbol: fur
gene_biotype: protein_coding
description:
  Ferric uptake regulator, Fur family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: TH3_08335
symbol: znuC
gene_biotype: protein_coding
description:
  High-affinity zinc transporter ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: TH3_08365
symbol: TH3_08365
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: TH3_08380
symbol: TH3_08380
gene_biotype: protein_coding
description:
  Threonyl/alanyl tRNA synthetase SAD; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.


ensembl_gene_id: TH3_08425
symbol: TH3_08425
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: TH3_08430
symbol: TH3_08430
gene_biotype: protein_coding
description:
  Flavin dependent oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: TH3_08455
symbol: nudF
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase NudF; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: TH3_08530
symbol: TH3_08530
gene_biotype: protein_coding
description:
  SirA-like domain-containing protein; COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: TH3_08555
symbol: TH3_08555
gene_biotype: protein_coding
description:
  Diguanylate cyclase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.


ensembl_gene_id: TH3_08605
symbol: TH3_08605
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: TH3_08610
symbol: hisZ
gene_biotype: protein_coding
description:
  Putative ATP phosphoribosyltransferase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: TH3_08615
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: TH3_08630
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: TH3_08635
symbol: TH3_08635
gene_biotype: protein_coding
description:
  Pseudouridylate synthase, 23S RNA-specific; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: TH3_08645
symbol: TH3_08645
gene_biotype: protein_coding
description:
  Peptidase M67 family protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.


ensembl_gene_id: TH3_08725
symbol: TH3_08725
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: TH3_08740
symbol: TH3_08740
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: TH3_08750
symbol: TH3_08750
gene_biotype: protein_coding
description:
  Glycine betaine transporter membrane protein; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: TH3_08765
symbol: TH3_08765
gene_biotype: protein_coding
description:
  Glycine/betaine ABC transporter periplasmic protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: TH3_08770
symbol: TH3_08770
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.


ensembl_gene_id: TH3_08775
symbol: TH3_08775
gene_biotype: protein_coding
description:
  iron(III) ABC transporter periplasmic iron-compound-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: TH3_08780
symbol: TH3_08780
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: TH3_08785
symbol: TH3_08785
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: TH3_08790
symbol: TH3_08790
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: TH3_08795
symbol: TH3_08795
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: TH3_08835
symbol: TH3_08835
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein, putative dipeptide/oligopeptide/nickel transporter; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_08840
symbol: TH3_08840
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: TH3_08870
symbol: mnmC
gene_biotype: protein_coding
description:
  Bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: TH3_08875
symbol: dusA
gene_biotype: protein_coding
description:
  TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: TH3_08900
symbol: TH3_08900
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_08925
symbol: TH3_08925
gene_biotype: protein_coding
description:
  Putative signal transduction phosphotransferase; COG0643 Chemotaxis protein histidine kinase and related kinases.


ensembl_gene_id: TH3_08930
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: TH3_08935
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...]


ensembl_gene_id: TH3_08945
symbol: plsY
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: TH3_08955
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: TH3_08970
symbol: TH3_08970
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: TH3_08975
symbol: gatC
gene_biotype: protein_coding
description:
  asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: TH3_08980
symbol: gatA
gene_biotype: protein_coding
description:
  glutamyl-tRNA amidotransferase, subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: TH3_08985
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: TH3_09035
symbol: TH3_09035
gene_biotype: protein_coding
description:
  Chromosome replication initiation inhibitor protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TH3_09060
symbol: TH3_09060
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: TH3_09090
symbol: TH3_09090
gene_biotype: protein_coding
description:
  Tripartite ATP-independent periplasmic transporter DctQ; COG4665 TRAP-type mannitol/chloroaromatic compound transport system, small permease component.


ensembl_gene_id: TH3_09130
symbol: TH3_09130
gene_biotype: protein_coding
description:
  5'-nucleotidase domain-containing protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: TH3_09140
symbol: TH3_09140
gene_biotype: protein_coding
description:
  Nucleoside ABC transporter substrate-binding protein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: TH3_09145
symbol: TH3_09145
gene_biotype: protein_coding
description:
  Sugar ABC transporter ATP-binding protein; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: TH3_09150
symbol: TH3_09150
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_09155
symbol: TH3_09155
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_09170
symbol: TH3_09170
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: TH3_09175
symbol: TH3_09175
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: TH3_09180
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: TH3_09200
symbol: TH3_09200
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.


ensembl_gene_id: TH3_09215
symbol: TH3_09215
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: TH3_09240
symbol: TH3_09240
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: TH3_09265
symbol: msrA
gene_biotype: protein_coding
description:
  Methionine-s-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: TH3_09290
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: TH3_09365
symbol: secF
gene_biotype: protein_coding
description:
  Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.


ensembl_gene_id: TH3_09400
symbol: TH3_09400
gene_biotype: protein_coding
description:
  protein-L-isoaspartate(D-aspartate) O-methyltransferase; COG2518 Protein-L-isoaspartate carboxylmethyltransferase.


ensembl_gene_id: TH3_09410
symbol: TH3_09410
gene_biotype: protein_coding
description:
  Type I secretion outer membrane protein, TolC; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.


ensembl_gene_id: TH3_09420
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: TH3_09435
symbol: TH3_09435
gene_biotype: protein_coding
description:
  4-amino-4-deoxychorismate lyase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: TH3_09450
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: TH3_09485
symbol: TH3_09485
gene_biotype: protein_coding
description:
  Putative chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: TH3_09490
symbol: TH3_09490
gene_biotype: protein_coding
description:
  Transcription regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: TH3_09495
symbol: TH3_09495
gene_biotype: protein_coding
description:
  Putative spermidine/putrescine ABC transporter,(ATP-binding protein); COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_09500
symbol: tatA
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: TH3_09505
symbol: tatB
gene_biotype: protein_coding
description:
  TatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: TH3_09510
symbol: tatC
gene_biotype: protein_coding
description:
  TatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: TH3_09515
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: TH3_09520
symbol: surE
gene_biotype: protein_coding
description:
  5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: TH3_09525
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: TH3_09540
symbol: yajC
gene_biotype: protein_coding
description:
  Protein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: TH3_09545
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: TH3_09550
symbol: secF-2
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: TH3_09585
symbol: trmFO
gene_biotype: protein_coding
description:
  Glucose inhibited division protein Gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: TH3_09595
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: TH3_09600
symbol: TH3_09600
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: TH3_09615
symbol: TH3_09615
gene_biotype: protein_coding
description:
  Glutamine--fructose-6-phosphate transaminase (isomerizing); COG2222 Predicted phosphosugar isomerases.


ensembl_gene_id: TH3_09650
symbol: TH3_09650
gene_biotype: protein_coding
description:
  Maltose/maltodextrin import ATP-binding protein MalK; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_09675
symbol: TH3_09675
gene_biotype: protein_coding
description:
  Sn-glycerol 3-phosphate ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_09685
symbol: ugpE
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: TH3_09690
symbol: ugpC
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: TH3_09700
symbol: TH3_09700
gene_biotype: protein_coding
description:
  ssDNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: TH3_09710
symbol: TH3_09710
gene_biotype: protein_coding
description:
  Putative MutT/nudix family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: TH3_09720
symbol: TH3_09720
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: TH3_09740
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: TH3_09750
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: TH3_09760
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: TH3_09765
symbol: TH3_09765
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: TH3_09775
symbol: TH3_09775
gene_biotype: protein_coding
description:
  Amino acid ABC transporter permease; COG4160 ABC-type arginine/histidine transport system, permease component.


ensembl_gene_id: TH3_09780
symbol: TH3_09780
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG4215 ABC-type arginine transport system, permease component.


ensembl_gene_id: TH3_09785
symbol: TH3_09785
gene_biotype: protein_coding
description:
  Family 3 extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: TH3_09805
symbol: rlpA
gene_biotype: protein_coding
description:
  Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: TH3_09810
symbol: TH3_09810
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.


ensembl_gene_id: TH3_09815
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: TH3_09825
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.


ensembl_gene_id: TH3_09845
symbol: ectA
gene_biotype: protein_coding
description:
  L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.


ensembl_gene_id: TH3_09850
symbol: TH3_09850
gene_biotype: protein_coding
description:
  Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_09855
symbol: ectC
gene_biotype: protein_coding
description:
  L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.


ensembl_gene_id: TH3_09870
symbol: TH3_09870
gene_biotype: protein_coding
description:
  Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: TH3_09875
symbol: hflX
gene_biotype: protein_coding
description:
  GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: TH3_09880
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: TH3_09890
symbol: trkA
gene_biotype: protein_coding
description:
  Potassium transporter peripheral membrane component; COG0569 K+ transport systems, NAD-binding component.


ensembl_gene_id: TH3_09895
symbol: TH3_09895
gene_biotype: protein_coding
description:
  Two-component response regulator, Fis-type:Nitrogen regulation protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: TH3_09900
symbol: TH3_09900
gene_biotype: protein_coding
description:
  COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.


ensembl_gene_id: TH3_09905
symbol: ntrC
gene_biotype: protein_coding
description:
  Transcriptional regulator involved in nitrogen fixation; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: TH3_09915
symbol: TH3_09915
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: TH3_09925
symbol: ispDF
gene_biotype: protein_coding
description:
  IspD protein; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).


ensembl_gene_id: TH3_09930
symbol: TH3_09930
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: TH3_09955
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: TH3_09960
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: TH3_09965
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: TH3_09985
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: TH3_09990
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: TH3_09995
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: TH3_10000
symbol: ribB-2
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein ribA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: TH3_10010
symbol: TH3_10010
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: TH3_10015
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: TH3_10020
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: TH3_10035
symbol: TH3_10035
gene_biotype: protein_coding
description:
  Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: TH3_10060
symbol: TH3_10060
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_10070
symbol: TH3_10070
gene_biotype: protein_coding
description:
  COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family.


ensembl_gene_id: TH3_10140
symbol: TH3_10140
gene_biotype: protein_coding
description:
  Flavin reductase like domain protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: TH3_10155
symbol: bpt
gene_biotype: protein_coding
description:
  arginyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: TH3_10165
symbol: TH3_10165
gene_biotype: protein_coding
description:
  C4 dicarboxylate transporter permease; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.


ensembl_gene_id: TH3_10175
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: TH3_10190
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: TH3_10195
symbol: rnc
gene_biotype: protein_coding
description:
  dsRNA-specific ribonuclease; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: TH3_10205
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: TH3_10210
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: TH3_10220
symbol: TH3_10220
gene_biotype: protein_coding
description:
  Guanosine polyphosphate pyrophosphohydrolase/synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: TH3_10225
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: TH3_10260
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: TH3_10265
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: TH3_10270
symbol: TH3_10270
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: TH3_10290
symbol: TH3_10290
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: TH3_10295
symbol: TH3_10295
gene_biotype: protein_coding
description:
  CinA domain-containing protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: TH3_10305
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: TH3_10315
symbol: TH3_10315
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: TH3_10320
symbol: TH3_10320
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: TH3_10325
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (Acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: TH3_10335
symbol: eno
gene_biotype: protein_coding
description:
  Enolase (2-phosphoglycerate dehydratase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: TH3_10340
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.


ensembl_gene_id: TH3_10345
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: TH3_10350
symbol: TH3_10350
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: TH3_10355
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: TH3_10365
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: TH3_10400
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: TH3_10410
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: TH3_10415
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: TH3_10440
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: TH3_10450
symbol: lpxA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: TH3_10455
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: TH3_10460
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: TH3_10470
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: TH3_10480
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: TH3_10490
symbol: TH3_10490
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: TH3_10495
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: TH3_10505
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: TH3_10525
symbol: lolD
gene_biotype: protein_coding
description:
  Peptide ABC transporter ATPase; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: TH3_10530
symbol: TH3_10530
gene_biotype: protein_coding
description:
  Lipoprotein-releasing system permease; COG4591 ABC-type transport system, involved in lipoprotein release, permease component.


ensembl_gene_id: TH3_10535
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.


ensembl_gene_id: TH3_10560
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: TH3_10570
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: TH3_10580
symbol: TH3_10580
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: TH3_10585
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: TH3_10590
symbol: TH3_10590
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit 6; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: TH3_10595
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: TH3_10600
symbol: nuoH
gene_biotype: protein_coding
description:
  Respiratory-chain NADH dehydrogenase subunit 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: TH3_10605
symbol: TH3_10605
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: TH3_10610
symbol: TH3_10610
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: TH3_10620
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: TH3_10625
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: TH3_10630
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: TH3_10635
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: TH3_10640
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein G; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: TH3_10650
symbol: TH3_10650
gene_biotype: protein_coding
description:
  Nucleoid DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: TH3_10655
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: TH3_10660
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: TH3_10665
symbol: clpP
gene_biotype: protein_coding
description:
  Protease subunit of ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: TH3_10670
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: TH3_10675
symbol: nnrE
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: TH3_10835
symbol: TH3_10835
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: TH3_10840
symbol: TH3_10840
gene_biotype: protein_coding
description:
  TetR family transcriptional regulator; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: TH3_10850
symbol: TH3_10850
gene_biotype: protein_coding
description:
  Choline ABC transporter periplasmic protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: TH3_10855
symbol: TH3_10855
gene_biotype: protein_coding
description:
  Choline ABC transporter permease; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: TH3_10885
symbol: TH3_10885
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: TH3_10890
symbol: TH3_10890
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_10895
symbol: TH3_10895
gene_biotype: protein_coding
description:
  Class III aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_10960
symbol: TH3_10960
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC); Belongs to the peptidase M81 family.


ensembl_gene_id: TH3_10970
symbol: TH3_10970
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter- DctM subunit; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: TH3_11030
symbol: TH3_11030
gene_biotype: protein_coding
description:
  Transcriptional regulator; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family.


ensembl_gene_id: TH3_11035
symbol: TH3_11035
gene_biotype: protein_coding
description:
  Putative GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: TH3_11045
symbol: TH3_11045
gene_biotype: protein_coding
description:
  Beta-ketoadipyl CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: TH3_11075
symbol: TH3_11075
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactonase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: TH3_11080
symbol: TH3_11080
gene_biotype: protein_coding
description:
  Pca operon transcription factor PcaQ; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TH3_11090
symbol: TH3_11090
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.


ensembl_gene_id: TH3_11110
symbol: TH3_11110
gene_biotype: protein_coding
description:
  Aliphatic sulfonates transport permease protein SsuC; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: TH3_11115
symbol: TH3_11115
gene_biotype: protein_coding
description:
  Aliphatic sulfonates import ATP-binding protein SsuB; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: TH3_11120
symbol: TH3_11120
gene_biotype: protein_coding
description:
  Putative aliphatic sulfonates-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: TH3_11185
symbol: TH3_11185
gene_biotype: protein_coding
description:
  COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: TH3_11200
symbol: TH3_11200
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: TH3_11205
symbol: TH3_11205
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein, family 3; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: TH3_11260
symbol: TH3_11260
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: TH3_11310
symbol: TH3_11310
gene_biotype: protein_coding
description:
  Prophage PSPPH06 reverse transcriptase/maturase; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: TH3_11350
symbol: TH3_11350
gene_biotype: protein_coding
description:
  Monosaccharide-transporting ATPase; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: TH3_11365
symbol: TH3_11365
gene_biotype: protein_coding
description:
  Periplasmic-binding protein/LacI transcriptional regulator; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_11385
symbol: TH3_11385
gene_biotype: protein_coding
description:
  Sialic acid TRAP transporter permease protein siaT; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.


ensembl_gene_id: TH3_11390
symbol: TH3_11390
gene_biotype: protein_coding
description:
  Tripartite ATP-independent periplasmic transporter DctQ component; COG4665 TRAP-type mannitol/chloroaromatic compound transport system, small permease component.


ensembl_gene_id: TH3_11395
symbol: TH3_11395
gene_biotype: protein_coding
description:
  C4-dicarboxylate-binding periplasmic protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: TH3_11440
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: TH3_11450
symbol: TH3_11450
gene_biotype: protein_coding
description:
  Putative chemotaxis methyl-accepting receptor (PAS and HAMP domains); COG0840 Methyl-accepting chemotaxis protein.


ensembl_gene_id: TH3_11465
symbol: TH3_11465
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: TH3_11510
symbol: TH3_11510
gene_biotype: protein_coding
description:
  TRAP C4-dicarboxylate transport system permease subunit DctP; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: TH3_11515
symbol: TH3_11515
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding protein,family 7, putative; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: TH3_11555
symbol: TH3_11555
gene_biotype: protein_coding
description:
  2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; COG3553 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: TH3_11580
symbol: TH3_11580
gene_biotype: protein_coding
description:
  Cyclophilin type peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: TH3_11585
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: TH3_11590
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: TH3_11595
symbol: TH3_11595
gene_biotype: protein_coding
description:
  Inner membrane transporter yedA; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: TH3_11730
symbol: TH3_11730
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TH3_11790
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: TH3_11795
symbol: TH3_11795
gene_biotype: protein_coding
description:
  Tena; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.


ensembl_gene_id: TH3_11810
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: TH3_11815
symbol: hscB
gene_biotype: protein_coding
description:
  DnaJ-domain-containing protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: TH3_11825
symbol: TH3_11825
gene_biotype: protein_coding
description:
  Scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: TH3_11830
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: TH3_11860
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: TH3_11865
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: TH3_11875
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: TH3_11925
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: TH3_11950
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: TH3_11980
symbol: thiG
gene_biotype: protein_coding
description:
  Bifunctional sulfur carrier protein/thiazole synthase protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: TH3_11990
symbol: TH3_11990
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: TH3_11995
symbol: TH3_11995
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: TH3_12005
symbol: aat
gene_biotype: protein_coding
description:
  Leucyl, phenylalanyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: TH3_12015
symbol: TH3_12015
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TH3_12040
symbol: TH3_12040
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: TH3_12045
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: TH3_12105
symbol: TH3_12105
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2342 Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase.


ensembl_gene_id: TH3_12120
symbol: TH3_12120
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: TH3_12130
symbol: TH3_12130
gene_biotype: protein_coding
description:
  Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: TH3_12190
symbol: TH3_12190
gene_biotype: protein_coding
description:
  Oxidoreductase probably involved in sulfite reduction; COG3749 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: TH3_12250
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein OstA; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.


ensembl_gene_id: TH3_12260
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: TH3_12265
symbol: rsmA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: TH3_12285
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: TH3_12290
symbol: TH3_12290
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl carrier protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: TH3_12300
symbol: TH3_12300
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: TH3_12315
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: TH3_12330
symbol: TH3_12330
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: TH3_12335
symbol: TH3_12335
gene_biotype: protein_coding
description:
  Putative alanine racemase, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: TH3_12340
symbol: TH3_12340
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0767 ABC-type transport system involved in resistance to organic solvents, permease component.


ensembl_gene_id: TH3_12345
symbol: TH3_12345
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.


ensembl_gene_id: TH3_12350
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: TH3_12360
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: TH3_12385
symbol: TH3_12385
gene_biotype: protein_coding
description:
  Thiol--disulfide interchange redox-active center transmembrane protein; COG0526 Thiol-disulfide isomerase and thioredoxins.


ensembl_gene_id: TH3_12390
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: TH3_12420
symbol: nrdF
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: TH3_12425
symbol: TH3_12425
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: TH3_12435
symbol: TH3_12435
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: TH3_12445
symbol: TH3_12445
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: TH3_12455
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: TH3_12460
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: TH3_12465
symbol: TH3_12465
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: TH3_12470
symbol: TH3_12470
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: TH3_12475
symbol: TH3_12475
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: TH3_12480
symbol: TH3_12480
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: TH3_12485
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: TH3_12490
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: TH3_12505
symbol: TH3_12505
gene_biotype: protein_coding
description:
  Monosaccharide-transporting ATPase; COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_12515
symbol: TH3_12515
gene_biotype: protein_coding
description:
  Putative sugar uptake ABC transporter periplasmic solute-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: TH3_12540
symbol: msrB
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.


ensembl_gene_id: TH3_12555
symbol: TH3_12555
gene_biotype: protein_coding
description:
  Beta-lactamase-like protein; COG1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain.


ensembl_gene_id: TH3_12565
symbol: TH3_12565
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: TH3_12595
symbol: TH3_12595
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_12715
symbol: TH3_12715
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TH3_12745
symbol: TH3_12745
gene_biotype: protein_coding
description:
  Putative aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: TH3_12750
symbol: TH3_12750
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: TH3_12760
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: TH3_12765
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: TH3_12770
symbol: TH3_12770
gene_biotype: protein_coding
description:
  Aminotransferase, class III; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_12780
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: TH3_12785
symbol: cysC
gene_biotype: protein_coding
description:
  Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: TH3_12805
symbol: dnaE2
gene_biotype: protein_coding
description:
  DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: TH3_12815
symbol: TH3_12815
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_12830
symbol: TH3_12830
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_12860
symbol: TH3_12860
gene_biotype: protein_coding
description:
  Nitrite reductase (NAD(P)H) large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: TH3_12865
symbol: TH3_12865
gene_biotype: protein_coding
description:
  Assimilatory nitrite reductase small subunit,Ferredoxin; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: TH3_12870
symbol: TH3_12870
gene_biotype: protein_coding
description:
  Nitrate reductase, large subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: TH3_12925
symbol: TH3_12925
gene_biotype: protein_coding
description:
  Oxidoreductase YvaG; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: TH3_12950
symbol: TH3_12950
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: TH3_12955
symbol: TH3_12955
gene_biotype: protein_coding
description:
  COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: TH3_12960
symbol: TH3_12960
gene_biotype: protein_coding
description:
  Iron-sulfur cluster-binding protein; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: TH3_12985
symbol: purU-2
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: TH3_12990
symbol: TH3_12990
gene_biotype: protein_coding
description:
  Glycine cleavage system T protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.


ensembl_gene_id: TH3_12995
symbol: TH3_12995
gene_biotype: protein_coding
description:
  Formaldehyde dehydrogenase, glutathione-independent; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: TH3_13010
symbol: TH3_13010
gene_biotype: protein_coding
description:
  Putative siderophore ABC transporter, solute-binding periplasmic component; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: TH3_13025
symbol: TH3_13025
gene_biotype: protein_coding
description:
  Putative sigma-70 factor, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_13035
symbol: TH3_13035
gene_biotype: protein_coding
description:
  TonB-dependent siderophore receptor precursor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: TH3_13040
symbol: TH3_13040
gene_biotype: protein_coding
description:
  Iron-hydroxamate transporter ATP-binding subunit; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: TH3_13045
symbol: TH3_13045
gene_biotype: protein_coding
description:
  Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: TH3_13050
symbol: TH3_13050
gene_biotype: protein_coding
description:
  Iron-hydroxamate transporter permease subunit; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: TH3_13060
symbol: TH3_13060
gene_biotype: protein_coding
description:
  Ferric regulator sigma-24 subunit; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_13070
symbol: TH3_13070
gene_biotype: protein_coding
description:
  Vicibactin biosynthesis non-ribosomal peptide synthase; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: TH3_13185
symbol: TH3_13185
gene_biotype: protein_coding
description:
  Type II/IV secretion system protein; COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis.


ensembl_gene_id: TH3_13225
symbol: TH3_13225
gene_biotype: protein_coding
description:
  Type I restriction-modification system restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: TH3_13235
symbol: TH3_13235
gene_biotype: protein_coding
description:
  Restriction modification system DNA specificity domain-containing protein; COG0732 Restriction endonuclease S subunits.


ensembl_gene_id: TH3_13270
symbol: TH3_13270
gene_biotype: protein_coding
description:
  Phage replication initiation protein; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain.


ensembl_gene_id: TH3_13290
symbol: TH3_13290
gene_biotype: protein_coding
description:
  Amino acid dehydrogenase transmembrane protein; COG0665 Glycine/D-amino acid oxidases (deaminating).


ensembl_gene_id: TH3_13305
symbol: TH3_13305
gene_biotype: protein_coding
description:
  Oxidoreductase domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: TH3_13315
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: TH3_13320
symbol: TH3_13320
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: TH3_13330
symbol: TH3_13330
gene_biotype: protein_coding
description:
  Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: TH3_13395
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: TH3_13400
symbol: TH3_13400
gene_biotype: protein_coding
description:
  Quaternary ammonium compound-resistance protein SugE; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: TH3_13415
symbol: TH3_13415
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: TH3_13430
symbol: TH3_13430
gene_biotype: protein_coding
description:
  Nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase; COG0388 Predicted amidohydrolase.


ensembl_gene_id: TH3_13435
symbol: TH3_13435
gene_biotype: protein_coding
description:
  Beta alanine--pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_13445
symbol: TH3_13445
gene_biotype: protein_coding
description:
  Amino acid-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: TH3_13450
symbol: TH3_13450
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: TH3_13460
symbol: TH3_13460
gene_biotype: protein_coding
description:
  Dihydropyrimidine dehydrogenase subunit A; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: TH3_13470
symbol: TH3_13470
gene_biotype: protein_coding
description:
  Spermidine/putrescine transport system substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: TH3_13475
symbol: TH3_13475
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_13545
symbol: TH3_13545
gene_biotype: protein_coding
description:
  Ferrichrome-binding periplasmic protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: TH3_13550
symbol: TH3_13550
gene_biotype: protein_coding
description:
  Hydroxamate-dependent iron ABC transporter periplasmic protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: TH3_13600
symbol: TH3_13600
gene_biotype: protein_coding
description:
  TRAP transporter substrate-binding protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: TH3_13605
symbol: TH3_13605
gene_biotype: protein_coding
description:
  5-dehydro-4-deoxyglucarate dehydratase; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: TH3_13645
symbol: TH3_13645
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: TH3_13670
symbol: TH3_13670
gene_biotype: protein_coding
description:
  D-xylose ABC transporter, substrate-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: TH3_13675
symbol: TH3_13675
gene_biotype: protein_coding
description:
  Putative permease protein, ABC transporter; COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_13680
symbol: TH3_13680
gene_biotype: protein_coding
description:
  D-xylose ABC transporter, ATP-binding component; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: TH3_13740
symbol: TH3_13740
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family.


ensembl_gene_id: TH3_13785
symbol: TH3_13785
gene_biotype: protein_coding
description:
  Putative ferric-citrate TonB-dependent receptor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: TH3_13795
symbol: TH3_13795
gene_biotype: protein_coding
description:
  Putative membrane transport ATP-binding protein; COG4178 ABC-type uncharacterized transport system, permease and ATPase components.


ensembl_gene_id: TH3_13860
symbol: TH3_13860
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG2984 ABC-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: TH3_13880
symbol: TH3_13880
gene_biotype: protein_coding
description:
  Cyclic peptide transporter; COG4615 ABC-type siderophore export system, fused ATPase and permease components.


ensembl_gene_id: TH3_13890
symbol: TH3_13890
gene_biotype: protein_coding
description:
  Erythronolide synthase; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: TH3_13920
symbol: acpP-2
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: TH3_13950
symbol: TH3_13950
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: TH3_13970
symbol: TH3_13970
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: TH3_13975
symbol: TH3_13975
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; COG4706 Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase.


ensembl_gene_id: TH3_13980
symbol: TH3_13980
gene_biotype: protein_coding
description:
  3-ketoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_14010
symbol: TH3_14010
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: TH3_14025
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: TH3_14030
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase KynU; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: TH3_14045
symbol: TH3_14045
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: TH3_14060
symbol: TH3_14060
gene_biotype: protein_coding
description:
  salicylyl-CoA 5-hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: TH3_14070
symbol: TH3_14070
gene_biotype: protein_coding
description:
  Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: TH3_14090
symbol: TH3_14090
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate-requiring enzyme; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family.


ensembl_gene_id: TH3_14105
symbol: TH3_14105
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: TH3_14130
symbol: kduI
gene_biotype: protein_coding
description:
  5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.


ensembl_gene_id: TH3_14140
symbol: TH3_14140
gene_biotype: protein_coding
description:
  2-deoxy-D-gluconate 3-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_14230
symbol: TH3_14230
gene_biotype: protein_coding
description:
  Putative conjugal transfer TrbD transmembrane protein; COG5268 Type IV secretory pathway, TrbD component.


ensembl_gene_id: TH3_14285
symbol: TH3_14285
gene_biotype: protein_coding
description:
  ANTAR domain-containing protein; COG3707 Response regulator with putative antiterminator output domain.


ensembl_gene_id: TH3_14295
symbol: TH3_14295
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: TH3_14320
symbol: TH3_14320
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: TH3_14375
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: TH3_14395
symbol: TH3_14395
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_14455
symbol: TH3_14455
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: TH3_14495
symbol: TH3_14495
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: TH3_14500
symbol: TH3_14500
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG4597 ABC-type amino acid transport system, permease component.


ensembl_gene_id: TH3_14505
symbol: TH3_14505
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: TH3_14525
symbol: cyaY
gene_biotype: protein_coding
description:
  Protein implicated in iron transport; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: TH3_14530
symbol: rpmE
gene_biotype: protein_coding
description:
  50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.


ensembl_gene_id: TH3_14550
symbol: TH3_14550
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: TH3_14610
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: TH3_14620
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: TH3_14635
symbol: purE
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: TH3_14640
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: TH3_14655
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: TH3_14690
symbol: TH3_14690
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: TH3_14735
symbol: clpB
gene_biotype: protein_coding
description:
  Chaperone clpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: TH3_14755
symbol: prmC
gene_biotype: protein_coding
description:
  Modification methylase HemK; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: TH3_14760
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: TH3_14765
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: TH3_14775
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: TH3_14785
symbol: TH3_14785
gene_biotype: protein_coding
description:
  COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: TH3_14800
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: TH3_14830
symbol: TH3_14830
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: TH3_14870
symbol: TH3_14870
gene_biotype: protein_coding
description:
  Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: TH3_14890
symbol: TH3_14890
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: TH3_14950
symbol: TH3_14950
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: TH3_14965
symbol: TH3_14965
gene_biotype: protein_coding
description:
  COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_14970
symbol: TH3_14970
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATP-binding protein-like protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_14975
symbol: TH3_14975
gene_biotype: protein_coding
description:
  Protease Do; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: TH3_15050
symbol: TH3_15050
gene_biotype: protein_coding
description:
  Glycerol metabolism activator AgmR; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: TH3_15065
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: TH3_15070
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in  [...]


ensembl_gene_id: TH3_15075
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: TH3_15080
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: TH3_15100
symbol: TH3_15100
gene_biotype: protein_coding
description:
  Mrp protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: TH3_15120
symbol: TH3_15120
gene_biotype: protein_coding
description:
  Peptidase S1C, Do; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: TH3_15140
symbol: TH3_15140
gene_biotype: protein_coding
description:
  Putative plasmid stability protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.


ensembl_gene_id: TH3_15145
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: TH3_15150
symbol: TH3_15150
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: TH3_15160
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: TH3_15165
symbol: psuG
gene_biotype: protein_coding
description:
  Pigment biosynthesis protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: TH3_15195
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: TH3_15205
symbol: TH3_15205
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: TH3_15210
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: TH3_15230
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: TH3_15235
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: TH3_15240
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: TH3_15265
symbol: TH3_15265
gene_biotype: protein_coding
description:
  HTH-type LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: TH3_15285
symbol: TH3_15285
gene_biotype: protein_coding
description:
  NADPH:quinone reductase-like protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: TH3_15315
symbol: TH3_15315
gene_biotype: protein_coding
description:
  Glycine cleavage T-C-terminal barrel domain-containing protein; COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family.


ensembl_gene_id: TH3_15320
symbol: TH3_15320
gene_biotype: protein_coding
description:
  Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: TH3_15355
symbol: TH3_15355
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein, family 7; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: TH3_15365
symbol: TH3_15365
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase; COG4664 TRAP-type mannitol/chloroaromatic compound transport system, large permease component.


ensembl_gene_id: TH3_15405
symbol: TH3_15405
gene_biotype: protein_coding
description:
  TRAP transporter solute receptor, TAXI family precursor; COG2358 TRAP-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: TH3_15445
symbol: cpdA-2
gene_biotype: protein_coding
description:
  Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: TH3_15450
symbol: queG
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: TH3_15470
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: TH3_15475
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine/archaeosine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribo [...]


ensembl_gene_id: TH3_15480
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: TH3_15485
symbol: TH3_15485
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: TH3_15515
symbol: TH3_15515
gene_biotype: protein_coding
description:
  CRP family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_15650
symbol: TH3_15650
gene_biotype: protein_coding
description:
  DctM (C4-dicarboxylate permease, large subunit); COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: TH3_15660
symbol: TH3_15660
gene_biotype: protein_coding
description:
  DctP (periplasmic C4-dicarboxylate binding protein); COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: TH3_15670
symbol: TH3_15670
gene_biotype: protein_coding
description:
  marR-family transcriptional Regulator; COG5631 Predicted transcription regulator, contains HTH domain (MarR family).


ensembl_gene_id: TH3_15715
symbol: TH3_15715
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: TH3_15735
symbol: corA
gene_biotype: protein_coding
description:
  Mg2 transporter protein CorA family protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: TH3_15750
symbol: mraZ
gene_biotype: protein_coding
description:
  Cell division protein MraZ; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: TH3_15755
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: TH3_15770
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: TH3_15775
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: TH3_15780
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: TH3_15785
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: TH3_15820
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: TH3_15835
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: TH3_15840
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: TH3_15885
symbol: TH3_15885
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATP-binding protein-like protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_15910
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: TH3_15915
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: TH3_15920
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: TH3_15925
symbol: bamD
gene_biotype: protein_coding
description:
  DNA uptake lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: TH3_15935
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: TH3_15980
symbol: TH3_15980
gene_biotype: protein_coding
description:
  Glucose-1-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_16035
symbol: TH3_16035
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: TH3_16040
symbol: TH3_16040
gene_biotype: protein_coding
description:
  Homocysteine S-methyltransferase; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.


ensembl_gene_id: TH3_16045
symbol: TH3_16045
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: TH3_16080
symbol: TH3_16080
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains.


ensembl_gene_id: TH3_16100
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate ABC transporter permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: TH3_16105
symbol: modC
gene_biotype: protein_coding
description:
  Molybdate ABC transporter ATPase; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: TH3_16115
symbol: TH3_16115
gene_biotype: protein_coding
description:
  Glyoxylate reductase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: TH3_16130
symbol: TH3_16130
gene_biotype: protein_coding
description:
  Sarcosine oxidase subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.


ensembl_gene_id: TH3_16145
symbol: TH3_16145
gene_biotype: protein_coding
description:
  CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_16185
symbol: TH3_16185
gene_biotype: protein_coding
description:
  Heme d1 biosynthesis protein NirD / Heme d1 biosynthesis protein NirL; COG1522 Transcriptional regulators.


ensembl_gene_id: TH3_16230
symbol: TH3_16230
gene_biotype: protein_coding
description:
  COG3256 Nitric oxide reductase large subunit; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: TH3_16235
symbol: TH3_16235
gene_biotype: protein_coding
description:
  Nitric oxide reductase, cytochrome c-containing subunit; COG2010 Cytochrome c, mono- and diheme variants.


ensembl_gene_id: TH3_16240
symbol: TH3_16240
gene_biotype: protein_coding
description:
  Hemerythrin hhe cation-binding domain-containing protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: TH3_16260
symbol: TH3_16260
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: TH3_16270
symbol: TH3_16270
gene_biotype: protein_coding
description:
  Copper-binding transport system membrane protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: TH3_16285
symbol: nosZ
gene_biotype: protein_coding
description:
  Nitrous-oxide reductase; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide; In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.


ensembl_gene_id: TH3_16295
symbol: TH3_16295
gene_biotype: protein_coding
description:
  KDP operon transcriptional regulatory protein kdpE; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: TH3_16300
symbol: TH3_16300
gene_biotype: protein_coding
description:
  OmpR family two component system sensor histidine kinase; COG2205 Osmosensitive K+ channel histidine kinase.


ensembl_gene_id: TH3_16305
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit KdpC; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: TH3_16310
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-translocating P-type ATPase B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: TH3_16315
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: TH3_16320
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: TH3_16325
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: TH3_16345
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: TH3_16425
symbol: TH3_16425
gene_biotype: protein_coding
description:
  Putative transcriptional regulatory protein,LysR family; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TH3_16430
symbol: msrP
gene_biotype: protein_coding
description:
  TMAO/DMSO reductase; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) [...]


ensembl_gene_id: TH3_16440
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: TH3_16455
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: TH3_16465
symbol: TH3_16465
gene_biotype: protein_coding
description:
  Transcriptional regulator of oxidative stress; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: TH3_16470
symbol: TH3_16470
gene_biotype: protein_coding
description:
  Putative rhomboid serine protease; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).


ensembl_gene_id: TH3_16485
symbol: napF
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: TH3_16490
symbol: napD
gene_biotype: protein_coding
description:
  Nitrate reductase accessory protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: TH3_16495
symbol: napA
gene_biotype: protein_coding
description:
  Nitrate reductase catalytic subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: TH3_16500
symbol: TH3_16500
gene_biotype: protein_coding
description:
  Nitrate reductase cytochrome c-type subunit (NapB); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: TH3_16520
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-dependent nucleic acid-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: TH3_16525
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: TH3_16530
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: TH3_16535
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: TH3_16555
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: TH3_16560
symbol: hldD
gene_biotype: protein_coding
description:
  ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: TH3_16575
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: TH3_16600
symbol: TH3_16600
gene_biotype: protein_coding
description:
  Oxidoreductase FAD/NAD(P)-binding subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: TH3_16630
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_16655
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: TH3_16660
symbol: trmL
gene_biotype: protein_coding
description:
  Putative aminotransferase/methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: TH3_16665
symbol: TH3_16665
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome C reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: TH3_16670
symbol: TH3_16670
gene_biotype: protein_coding
description:
  Cytochrome b/c1; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: TH3_16685
symbol: gloB
gene_biotype: protein_coding
description:
  Putative hydroxyacylglutathione hydrolase (Glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: TH3_16690
symbol: TH3_16690
gene_biotype: protein_coding
description:
  Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: TH3_16700
symbol: TH3_16700
gene_biotype: protein_coding
description:
  ABC transporter substrate binding protein (sugar); COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_16780
symbol: TH3_16780
gene_biotype: protein_coding
description:
  Polyhydroxyalkanoate synthesis repressor PhaR; COG5394 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: TH3_16795
symbol: TH3_16795
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains).


ensembl_gene_id: TH3_16800
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: TH3_16805
symbol: obg
gene_biotype: protein_coding
description:
  GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: TH3_16815
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: TH3_16825
symbol: TH3_16825
gene_biotype: protein_coding
description:
  Metal ABC transporter substrate-binding protein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: TH3_16875
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: TH3_16885
symbol: TH3_16885
gene_biotype: protein_coding
description:
  Putative Zn-dependent protease; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.


ensembl_gene_id: TH3_16895
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: TH3_16900
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: TH3_16965
symbol: TH3_16965
gene_biotype: protein_coding
description:
  2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: TH3_16990
symbol: TH3_16990
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: TH3_16995
symbol: TH3_16995
gene_biotype: protein_coding
description:
  Putative lipid metabolism-related protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: TH3_17035
symbol: TH3_17035
gene_biotype: protein_coding
description:
  Proline iminopeptidase (PIP) (prolyl aminopeptidase) (PAP); COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: TH3_17050
symbol: TH3_17050
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: TH3_17055
symbol: TH3_17055
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, CarD-like protein; COG1329 Transcriptional regulators, similar to M. xanthus CarD.


ensembl_gene_id: TH3_17060
symbol: TH3_17060
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: TH3_17125
symbol: TH3_17125
gene_biotype: protein_coding
description:
  Multiple resistance and pH regulation protein F; COG2212 Multisubunit Na+/H+ antiporter, MnhF subunit.


ensembl_gene_id: TH3_17145
symbol: TH3_17145
gene_biotype: protein_coding
description:
  Monovalent cation/H+ antiporter subunit A; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: TH3_17205
symbol: TH3_17205
gene_biotype: protein_coding
description:
  Sodium:neurotransmitter symporter; COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: TH3_17215
symbol: ccmA
gene_biotype: protein_coding
description:
  Heme ABC transporter (exporter), ATP-binding component; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: TH3_17220
symbol: TH3_17220
gene_biotype: protein_coding
description:
  ABC-type transport system involved in cytochrome c biogenesis, permease component; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: TH3_17225
symbol: ccmC
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CycZ; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: TH3_17230
symbol: TH3_17230
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CycX; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: TH3_17235
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: TH3_17245
symbol: TH3_17245
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CycY (periplasmic thioredoxin); COG0526 Thiol-disulfide isomerase and thioredoxins.


ensembl_gene_id: TH3_17265
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: TH3_17270
symbol: TH3_17270
gene_biotype: protein_coding
description:
  Periplasmic binding protein/LacI transcriptional regulator; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: TH3_17280
symbol: TH3_17280
gene_biotype: protein_coding
description:
  Sugar ABC transporter, permease component (RbsC-like) protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: TH3_17295
symbol: rbsK
gene_biotype: protein_coding
description:
  Deoxyribokinase/ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: TH3_17305
symbol: TH3_17305
gene_biotype: protein_coding
description:
  Transglycosylase; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: TH3_17315
symbol: TH3_17315
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: TH3_17360
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: TH3_17420
symbol: TH3_17420
gene_biotype: protein_coding
description:
  UBA/THIF-type NAD/FAD-binding protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: TH3_17440
symbol: cutC
gene_biotype: protein_coding
description:
  Copper homeostasis protein cutC; Participates in the control of copper homeostasis. Belongs to the CutC family.


ensembl_gene_id: TH3_17450
symbol: TH3_17450
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.


ensembl_gene_id: TH3_17460
symbol: TH3_17460
gene_biotype: protein_coding
description:
  CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_17465
symbol: TH3_17465
gene_biotype: protein_coding
description:
  Carboxypeptidase Taq; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: TH3_17480
symbol: TH3_17480
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase polypeptide III (cytochrome aa3 subunit 3); COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3.


ensembl_gene_id: TH3_17485
symbol: ctaG
gene_biotype: protein_coding
description:
  Cytochrome c oxidase assembly protein; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.


ensembl_gene_id: TH3_17490
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: TH3_17495
symbol: TH3_17495
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: TH3_17500
symbol: TH3_17500
gene_biotype: protein_coding
description:
  Cytochrome C oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: TH3_17510
symbol: TH3_17510
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: TH3_17515
symbol: TH3_17515
gene_biotype: protein_coding
description:
  Putative suppressor for copper-sensitivity B; COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis.


ensembl_gene_id: TH3_17525
symbol: TH3_17525
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: TH3_17540
symbol: TH3_17540
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain.


ensembl_gene_id: TH3_17545
symbol: gcvPA
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: TH3_17550
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: TH3_17570
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: TH3_17575
symbol: thrB
gene_biotype: protein_coding
description:
  COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: TH3_17585
symbol: TH3_17585
gene_biotype: protein_coding
description:
  Diguanylate cyclase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: TH3_17625
symbol: cynS
gene_biotype: protein_coding
description:
  Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: TH3_17630
symbol: TH3_17630
gene_biotype: protein_coding
description:
  Cyanate ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: TH3_17635
symbol: TH3_17635
gene_biotype: protein_coding
description:
  Nitrate ABC transporter inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: TH3_17640
symbol: TH3_17640
gene_biotype: protein_coding
description:
  Nitrate transporter component, nrtA; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: TH3_17655
symbol: TH3_17655
gene_biotype: protein_coding
description:
  Putative ATP--cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: TH3_17680
symbol: rbsK-2
gene_biotype: protein_coding
description:
  Ribokinase, bacterial; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: TH3_17700
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: TH3_17705
symbol: TH3_17705
gene_biotype: protein_coding
description:
  Fusaric acid resistance protein; COG1289 Predicted membrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TH3_17755
symbol: TH3_17755
gene_biotype: protein_coding
description:
  Transporter; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: TH3_17770
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: TH3_17780
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: TH3_17805
symbol: TH3_17805
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: TH3_17815
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: TH3_17820
symbol: TH3_17820
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase family protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: TH3_17835
symbol: TH3_17835
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system (K(+)/H(+) antiporter); COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: TH3_17845
symbol: TH3_17845
gene_biotype: protein_coding
description:
  Transcriptional repressor for high-affinity phosphate uptake; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: TH3_17850
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter ATPase; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: TH3_17860
symbol: TH3_17860
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease component; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: TH3_17865
symbol: TH3_17865
gene_biotype: protein_coding
description:
  Phosphate ABC transporter substrate-binding protein; COG0226 ABC-type phosphate transport system, periplasmic component.


ensembl_gene_id: TH3_17895
symbol: TH3_17895
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: TH3_17910
symbol: TH3_17910
gene_biotype: protein_coding
description:
  Crp/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: TH3_17935
symbol: TH3_17935
gene_biotype: protein_coding
description:
  Family 5 extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: TH3_17950
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: TH3_17965
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: TH3_18005
symbol: TH3_18005
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA.


ensembl_gene_id: TH3_18010
symbol: TH3_18010
gene_biotype: protein_coding
description:
  Pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: TH3_18020
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: TH3_18040
symbol: argJ
gene_biotype: protein_coding
description:
  Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: TH3_18105
symbol: TH3_18105
gene_biotype: protein_coding
description:
  Membrane ATPase/protein kinase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: TH3_18120
symbol: dusC
gene_biotype: protein_coding
description:
  NifR3/Smm1 family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: TH3_18135
symbol: TH3_18135
gene_biotype: protein_coding
description:
  Proteases secretion ATP-binding protein PrtD; COG4618 ABC-type protease/lipase transport system, ATPase and permease components.


ensembl_gene_id: TH3_18165
symbol: TH3_18165
gene_biotype: protein_coding
description:
  Transketolase central region; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: TH3_18175
symbol: TH3_18175
gene_biotype: protein_coding
description:
  Sigma54-dependent activator protein; COG3283 Transcriptional regulator of aromatic amino acids metabolism.


ensembl_gene_id: TH3_18205
symbol: TH3_18205
gene_biotype: protein_coding
description:
  COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: TH3_18240
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: TH3_18245
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: TH3_18250
symbol: ureE
gene_biotype: protein_coding
description:
  UreE urease accessory domain-containing protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: TH3_18260
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: TH3_18265
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: TH3_18270
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: TH3_18280
symbol: TH3_18280
gene_biotype: protein_coding
description:
  Urea or short-chain amide ABC transporter ATP-binding protein; COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: TH3_18325
symbol: TH3_18325
gene_biotype: protein_coding
description:
  Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: TH3_18330
symbol: TH3_18330
gene_biotype: protein_coding
description:
  Putative methyl-accepting chemotaxis sensory transducer; COG0840 Methyl-accepting chemotaxis protein.


ensembl_gene_id: TH3_18360
symbol: TH3_18360
gene_biotype: protein_coding
description:
  Putative ABC transporter, ATP-binding component; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: TH3_18385
symbol: TH3_18385
gene_biotype: protein_coding
description:
  Hydroxyisourate hydrolase; COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: TH3_18410
symbol: TH3_18410
gene_biotype: protein_coding
description:
  HAD-superfamily hydrolase, subfamily IA, variant 3; COG0637 Predicted phosphatase/phosphohexomutase.


ensembl_gene_id: TH3_18425
symbol: TH3_18425
gene_biotype: protein_coding
description:
  COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: TH3_18430
symbol: sdhA
gene_biotype: protein_coding
description:
  COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: TH3_18455
symbol: TH3_18455
gene_biotype: protein_coding
description:
  HlyD family secretion protein; COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: TH3_18475
symbol: TH3_18475
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: TH3_18510
symbol: TH3_18510
gene_biotype: protein_coding
description:
  DNA-binding transcriptional activator; COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain.


ensembl_gene_id: TH3_18525
symbol: TH3_18525
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: TH3_18575
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: TH3_18585
symbol: TH3_18585
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: TH3_18625
symbol: TH3_18625
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: TH3_18635
symbol: TH3_18635
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase (short-chain); COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: TH3_18675
symbol: TH3_18675
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter, ATP-binding components; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_18685
symbol: TH3_18685
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG4174 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: TH3_18720
symbol: TH3_18720
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein KefC; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: TH3_18775
symbol: TH3_18775
gene_biotype: protein_coding
description:
  TRAP transporter subunit DctP; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: TH3_18800
symbol: TH3_18800
gene_biotype: protein_coding
description:
  N-formimino-L-glutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: TH3_18820
symbol: TH3_18820
gene_biotype: protein_coding
description:
  2',5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: TH3_18830
symbol: TH3_18830
gene_biotype: protein_coding
description:
  Oxidoreductase Tas, aldo/keto reductase family protein; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: TH3_18850
symbol: TH3_18850
gene_biotype: protein_coding
description:
  Multifunctional: acyl-CoA thioesterase I/ protease I/ lysophospholipase L1; COG2755 Lysophospholipase L1 and related esterases.


ensembl_gene_id: TH3_18855
symbol: TH3_18855
gene_biotype: protein_coding
description:
  COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: TH3_18860
symbol: TH3_18860
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component.


ensembl_gene_id: TH3_18885
symbol: htpX
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: TH3_18890
symbol: TH3_18890
gene_biotype: protein_coding
description:
  RND transporter, hydrophobe/amphiphile efflux-1 family protein; COG0841 Cation/multidrug efflux pump.


ensembl_gene_id: TH3_18995
symbol: TH3_18995
gene_biotype: protein_coding
description:
  Thioredoxin 1; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.


ensembl_gene_id: TH3_19000
symbol: TH3_19000
gene_biotype: protein_coding
description:
  Helicase, UvrD; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: TH3_19005
symbol: TH3_19005
gene_biotype: protein_coding
description:
  Putative double-strand break repair protein, AddB-like protein; COG3893 Inactivated superfamily I helicase.


ensembl_gene_id: TH3_19010
symbol: TH3_19010
gene_biotype: protein_coding
description:
  Putative nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: TH3_19055
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: TH3_19065
symbol: TH3_19065
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: TH3_19070
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: TH3_19075
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: TH3_19080
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: TH3_19095
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: TH3_19115
symbol: TH3_19115
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: TH3_19130
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: TH3_19135
symbol: tsaD
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: TH3_19140
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: TH3_19145
symbol: TH3_19145
gene_biotype: protein_coding
description:
  Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: TH3_19155
symbol: TH3_19155
gene_biotype: protein_coding
description:
  Putative enzyme of heme biosynthesis (HemY-like) protein; COG2956 Predicted N-acetylglucosaminyl transferase.


ensembl_gene_id: TH3_19160
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: TH3_19165
symbol: TH3_19165
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein CapD; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: TH3_19170
symbol: TH3_19170
gene_biotype: protein_coding
description:
  COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: TH3_19175
symbol: TH3_19175
gene_biotype: protein_coding
description:
  Sun protein; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: TH3_19200
symbol: TH3_19200
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: TH3_19225
symbol: TH3_19225
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: TH3_19335
symbol: mdoG
gene_biotype: protein_coding
description:
  Glucan biosynthesis protein G; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: TH3_19390
symbol: TH3_19390
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: TH3_19395
symbol: TH3_19395
gene_biotype: protein_coding
description:
  Putative spermidine/putrescine ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: TH3_19400
symbol: TH3_19400
gene_biotype: protein_coding
description:
  ABC transporter nucleotide binding/ATPase (spermidine/putrescine); COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: TH3_19445
symbol: TH3_19445
gene_biotype: protein_coding
description:
  Two-component system hybrid sensor histidine kinase/response regulator protein; COG0784 FOG: CheY-like receiver.


ensembl_gene_id: TH3_19450
symbol: TH3_19450
gene_biotype: protein_coding
description:
  Metal-dependent hydrolase HDOD; COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain.


ensembl_gene_id: TH3_19480
symbol: TH3_19480
gene_biotype: protein_coding
description:
  Response regulator receiver:transcriptional regulatory protein, C-terminal; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: TH3_19485
symbol: TH3_19485
gene_biotype: protein_coding
description:
  Iron ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: TH3_19510
symbol: TH3_19510
gene_biotype: protein_coding
description:
  COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: TH3_19545
symbol: TH3_19545
gene_biotype: protein_coding
description:
  Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.


ensembl_gene_id: TH3_19590
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: TH3_19595
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: TH3_19600
symbol: accD
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: TH3_19605
symbol: TH3_19605
gene_biotype: protein_coding
description:
  Bifunctional tetrahydrofolate synthase/dihydrofolate synthase; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: TH3_19615
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: TH3_19620
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: TH3_19625
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: TH3_19640
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: TH3_19645
symbol: TH3_19645
gene_biotype: protein_coding
description:
  Putative branched-chain amino acid ABC transporter, periplasmic component; COG3107 Putative lipoprotein.


ensembl_gene_id: TH3_19650
symbol: rsmI
gene_biotype: protein_coding
description:
  Putative tetrapyrrole methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: TH3_19655
symbol: TH3_19655
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: TH3_19695
symbol: TH3_19695
gene_biotype: protein_coding
description:
  Nitrogen regulatory protein; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: TH3_19700
symbol: hpf
gene_biotype: protein_coding
description:
  Sigma 54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: TH3_19705
symbol: TH3_19705
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: TH3_19710
symbol: TH3_19710
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component.


ensembl_gene_id: TH3_19725
symbol: TH3_19725
gene_biotype: protein_coding
description:
  Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: TH3_19740
symbol: TH3_19740
gene_biotype: protein_coding
description:
  Glycosyl transferase, family 2 domain-containing protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: TH3_19745
symbol: TH3_19745
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase (HemN-like) protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: TH3_19750
symbol: TH3_19750
gene_biotype: protein_coding
description:
  dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: TH3_19755
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: TH3_19760
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: TH3_19765
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: TH3_19770
symbol: cobB
gene_biotype: protein_coding
description:
  COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: TH3_19790
symbol: TH3_19790
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: TH3_19815
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: TH3_19830
symbol: TH3_19830
gene_biotype: protein_coding
description:
  Putative iron-sulfur cluster scaffold, NifU-like protein; COG0694 Thioredoxin-like proteins and domains.


ensembl_gene_id: TH3_19860
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: TH3_19865
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: TH3_19870
symbol: murJ
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: TH3_19875
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: TH3_19885
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase-2 (GTP cyclohydrolase II); Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: TH3_19890
symbol: TH3_19890
gene_biotype: protein_coding
description:
  Two-component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: TH3_19895
symbol: TH3_19895
gene_biotype: protein_coding
description:
  Putative enzyme with PLP-binding domain alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: TH3_19945
symbol: TH3_19945
gene_biotype: protein_coding
description:
  Chromosome segregation DNA-binding protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: TH3_19955
symbol: rsmG
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase involved in cell division; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: TH3_19960
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: TH3_19965
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: TH3_19985
symbol: TH3_19985
gene_biotype: protein_coding
description:
  Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: TH3_19995
symbol: TH3_19995
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.


ensembl_gene_id: TH3_20000
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: TH3_20030
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: TH3_20035
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: TH3_20040
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: TH3_20045
symbol: TH3_20045
gene_biotype: protein_coding
description:
  Nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: TH3_20050
symbol: TH3_20050
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: TH3_20055
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: TH3_20060
symbol: hemH
gene_biotype: protein_coding
description:
  Protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: TH3_20070
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: TH3_20095
symbol: rlmN
gene_biotype: protein_coding
description:
  Fe-S-cluster redox protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: TH3_20115
symbol: TH3_20115
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: TH3_20120
symbol: gshB
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: TH3_20155
symbol: TH3_20155
gene_biotype: protein_coding
description:
  Putative DNA binding 3-demethylubiquinone-9 3-methyltransferase domain-containing protein; COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: TH3_20195
symbol: TH3_20195
gene_biotype: protein_coding
description:
  D-isomer-specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: TH3_20210
symbol: TH3_20210
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: TH3_20220
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: TH3_20230
symbol: TH3_20230
gene_biotype: protein_coding
description:
  Putative GCN5 N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: TH3_20235
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: TH3_20255
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: TH3_20260
symbol: hslU
gene_biotype: protein_coding
description:
  ATPase and chaperone, component of the HslUV proteasome; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: TH3_20280
symbol: TH3_20280
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase (CoaC), Phosphopantothenatecysteine ligase (CoaB); Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: TH3_20285
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: TH3_20300
symbol: TH3_20300
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeB; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: TH3_20360
symbol: TH3_20360
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: TH3_20370
symbol: TH3_20370
gene_biotype: protein_coding
description:
  SirA family protein; COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: TH3_20390
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: TH3_20400
symbol: ybeY
gene_biotype: protein_coding
description:
  Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: TH3_20410
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: TH3_20420
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: TH3_20425
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: TH3_20430
symbol: TH3_20430
gene_biotype: protein_coding
description:
  Fec I like protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: TH3_20440
symbol: TH3_20440
gene_biotype: protein_coding
description:
  TonB-dependent heme/hemoglobin receptor family protein; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: TH3_20450
symbol: TH3_20450
gene_biotype: protein_coding
description:
  Alkaline protease secretion ATP-binding protein AprD; COG4618 ABC-type protease/lipase transport system, ATPase and permease components.


ensembl_gene_id: TH3_20465
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: TH3_20470
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: TH3_20475
symbol: TH3_20475
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.


ensembl_gene_id: TH3_20480
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: TH3_20485
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: TH3_20490
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: TH3_20495
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: TH3_20500
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: TH3_20570
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: TH3_20590
symbol: TH3_20590
gene_biotype: protein_coding
description:
  Transglutaminase domain-containing protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: TH3_20635
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: TH3_20645
symbol: hldE
gene_biotype: protein_coding
description:
  ADP-heptose synthase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: TH3_20650
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: TH3_20660
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: TH3_20665
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: TH3_20680
symbol: cobU
gene_biotype: protein_coding
description:
  Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: TH3_20690
symbol: TH3_20690
gene_biotype: protein_coding
description:
  Cobaltochelatase CobN subunit; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: TH3_20705
symbol: TH3_20705
gene_biotype: protein_coding
description:
  cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: TH3_20710
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: TH3_20740
symbol: TH3_20740
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase 40 kDa subunit; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: TH3_20755
symbol: cbiD
gene_biotype: protein_coding
description:
  cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: TH3_20760
symbol: TH3_20760
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: TH3_20770
symbol: TH3_20770
gene_biotype: protein_coding
description:
  Classical-complement-pathway C3/C5 convertase; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: TH3_20775
symbol: cbiA
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: TH3_20835
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase/5-enolpyruvylshikimate-3- phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: TH3_20845
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: TH3_20855
symbol: TH3_20855
gene_biotype: protein_coding
description:
  Integration host factor beta-subunit (IHF-beta); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: TH3_20865
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: TH3_20880
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


