# pathwayInfo

id: PF17250
description: NADH-ubiquinone oxidoreductase 11 kDa subunit
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17250
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF17250_NADH-ubiquinone_oxidoreductase_11_kDa_subunit


id: PF17284
description: Spermidine synthase tetramerisation domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17284
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF17284_Spermidine_synthase_tetramerisation_domain


id: PF17405
description: Nrap protein nucleotidyltransferase domain 4
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17405
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF17405_Nrap_protein_nucleotidyltransferase_domain_4


id: PF17408
description: Malonyl-CoA decarboxylase N-terminal domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17408
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF17408_Malonyl-CoA_decarboxylase_N-terminal_domain


id: PF17432
description: Domain of unknown function (DUF3458_C) ARM repeats
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17432
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF17432_Domain_of_unknown_function_(DUF3458_C)_ARM_repeats


id: PF17450
description: Alpha galactosidase A C-terminal beta sandwich domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17450
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF17450_Alpha_galactosidase_A_C-terminal_beta_sandwich_domain


id: PF17538
description: DNA Binding Domain (C-terminal) Leafy/Floricaula
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17538
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF17538_DNA_Binding_Domain_(C-terminal)_Leafy/Floricaula


id: PF18438
description: Glycosyl hydrolases family 38 C-terminal domain 1
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF18438
name:
  Protein Domains (Pfam).STRING_v12.0_112509_STRINGid_PF18438_Glycosyl_hydrolases_family_38_C-terminal_domain_1


id: SM00015
description: Short calmodulin-binding motif containing conserved Ile and Gln residues.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00015
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00015_Short_calmodulin-binding_motif_containing_conserved_Ile_and_Gln_residues.


id: SM00034
description: C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00034
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00034_C-type_lectin_(CTL)_or_carbohydrate-recognition_domain_(CRD)


id: SM00045
description: Diacylglycerol kinase accessory domain (presumed)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00045
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00045_Diacylglycerol_kinase_accessory_domain_(presumed)


id: SM00046
description: Diacylglycerol kinase catalytic domain (presumed)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00046
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00046_Diacylglycerol_kinase_catalytic_domain_(presumed)


id: SM00049
description: Domain found in Dishevelled, Egl-10, and Pleckstrin
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00049
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00049_Domain_found_in_Dishevelled,_Egl-10,_and_Pleckstrin


id: SM00064
description: Protein present in Fab1, YOTB, Vac1, and EEA1
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00064
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00064_Protein_present_in_Fab1,_YOTB,_Vac1,_and_EEA1


id: SM00065
description: Domain present in phytochromes and cGMP-specific phosphodiesterases.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00065
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00065_Domain_present_in_phytochromes_and_cGMP-specific_phosphodiesterases.


id: SM00079
description: Eukaryotic homologues of bacterial periplasmic substrate binding proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00079
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00079_Eukaryotic_homologues_of_bacterial_periplasmic_substrate_binding_proteins.


id: SM00086
description: Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00086
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00086_Motif_C-terminal_to_PAS_motifs_(likely_to_contribute_to_PAS_structural_domain)


id: SM00088
description: Motif in proteasome subunits, Int-6, Nip-1 and TRIP-15
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00088
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00088_Motif_in_proteasome_subunits,_Int-6,_Nip-1_and_TRIP-15


id: SM00100
description: Cyclic nucleotide-monophosphate binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00100
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00100_Cyclic_nucleotide-monophosphate_binding_domain


id: SM00102
description: Actin depolymerisation factor/cofilin -like domains
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00102
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00102_Actin_depolymerisation_factor/cofilin_-like_domains


id: SM00105
description: Putative GTP-ase activating proteins for the small GTPase, ARF
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00105
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00105_Putative_GTP-ase_activating_proteins_for_the_small_GTPase,_ARF


id: SM00109
description: Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00109
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00109_Protein_kinase_C_conserved_region_1_(C1)_domains_(Cysteine-rich_domains)


id: SM00116
description: Domain in cystathionine beta-synthase and other proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00116
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00116_Domain_in_cystathionine_beta-synthase_and_other_proteins.


id: SM00119
description: Domain Homologous to E6-AP Carboxyl Terminus with
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00119
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00119_Domain_Homologous_to_E6-AP_Carboxyl_Terminus_with


id: SM00128
description: Inositol polyphosphate phosphatase, catalytic domain homologues
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00128
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00128_Inositol_polyphosphate_phosphatase,_catalytic_domain_homologues


id: SM00129
description: Kinesin motor, catalytic domain. ATPase.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00129
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00129_Kinesin_motor,_catalytic_domain._ATPase.


id: SM00132
description: Zinc-binding domain present in Lin-11, Isl-1, Mec-3.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00132
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00132_Zinc-binding_domain_present_in_Lin-11,_Isl-1,_Mec-3.


id: SM00133
description: Extension to Ser/Thr-type protein kinases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00133
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00133_Extension_to_Ser/Thr-type_protein_kinases


id: SM00135
description: Low-density lipoprotein-receptor YWTD domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00135
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00135_Low-density_lipoprotein-receptor_YWTD_domain


id: SM00142
description: Phosphoinositide 3-kinase, region postulated to contain C2 domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00142
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00142_Phosphoinositide_3-kinase,_region_postulated_to_contain_C2_domain


id: SM00145
description: Phosphoinositide 3-kinase family, accessory domain (PIK domain)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00145
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00145_Phosphoinositide_3-kinase_family,_accessory_domain_(PIK_domain)


id: SM00146
description: Phosphoinositide 3-kinase, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00146
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00146_Phosphoinositide_3-kinase,_catalytic_domain


id: SM00148
description: Phospholipase C, catalytic domain (part)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00148
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00148_Phospholipase_C,_catalytic_domain_(part)


id: SM00149
description: Phospholipase C, catalytic domain (part)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00149
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00149_Phospholipase_C,_catalytic_domain_(part)


id: SM00156
description: Protein phosphatase 2A homologues, catalytic domain.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00156
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00156_Protein_phosphatase_2A_homologues,_catalytic_domain.


id: SM00164
description: Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00164
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00164_Domain_in_Tre-2,_BUB2p,_and_Cdc16p._Probable_Rab-GAPs.


id: SM00166
description: Domain present in ubiquitin-regulatory proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00166
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00166_Domain_present_in_ubiquitin-regulatory_proteins


id: SM00174
description: Rho (Ras homology) subfamily of Ras-like small GTPases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00174
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00174_Rho_(Ras_homology)_subfamily_of_Ras-like_small_GTPases


id: SM00176
description: Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00176
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00176_Ran_(Ras-related_nuclear_proteins)_/TC4_subfamily_of_small_GTPases


id: SM00178
description: Sar1p-like members of the Ras-family of small GTPases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00178
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00178_Sar1p-like_members_of_the_Ras-family__of_small_GTPases


id: SM00192
description: Low-density lipoprotein receptor domain class A
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00192
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00192_Low-density_lipoprotein_receptor_domain_class_A


id: SM00194
description: Protein tyrosine phosphatase, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00194
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00194_Protein_tyrosine_phosphatase,_catalytic_domain


id: SM00195
description: Dual specificity phosphatase, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00195
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00195_Dual_specificity_phosphatase,_catalytic_domain


id: SM00198
description: SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00198
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00198_SCP_/_Tpx-1_/_Ag5_/_PR-1_/_Sc7_family_of_extracellular_domains.


id: SM00208
description: Tumor necrosis factor receptor / nerve growth factor receptor repeats.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00208
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00208_Tumor_necrosis_factor_receptor_/_nerve_growth_factor_receptor_repeats.


id: SM00212
description: Ubiquitin-conjugating enzyme E2, catalytic domain homologues
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00212
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00212_Ubiquitin-conjugating_enzyme_E2,_catalytic_domain_homologues


id: SM00220
description: Serine/Threonine protein kinases, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00220
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00220_Serine/Threonine_protein_kinases,_catalytic_domain


id: SM00225
description: Broad-Complex, Tramtrack and Bric a brac
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00225
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00225_Broad-Complex,_Tramtrack_and_Bric_a_brac


id: SM00226
description: Low molecular weight phosphatase family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00226
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00226_Low_molecular_weight_phosphatase_family


id: SM00228
description: Domain present in PSD-95, Dlg, and ZO-1/2.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00228
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00228_Domain_present_in_PSD-95,_Dlg,_and_ZO-1/2.


id: SM00234
description: In StAR and phosphatidylcholine transfer protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00234
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00234_In_StAR_and_phosphatidylcholine_transfer_protein


id: SM00239
description: Protein kinase C conserved region 2 (CalB)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00239
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00239_Protein_kinase_C_conserved_region_2_(CalB)


id: SM00271
description: DnaJ molecular chaperone homology domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00271
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00271_DnaJ_molecular_chaperone_homology_domain


id: SM00273
description: Epsin N-terminal homology (ENTH) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00273
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00273_Epsin_N-terminal_homology_(ENTH)_domain


id: SM00278
description: Helix-hairpin-helix DNA-binding motif class 1
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00278
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00278_Helix-hairpin-helix_DNA-binding_motif_class_1


id: SM00279
description: Helix-hairpin-helix class 2 (Pol1 family) motifs
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00279
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00279_Helix-hairpin-helix_class_2_(Pol1_family)_motifs


id: SM00290
description: Ubiquitin Carboxyl-terminal Hydrolase-like zinc finger
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00290
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00290_Ubiquitin_Carboxyl-terminal_Hydrolase-like_zinc_finger


id: SM00291
description: Zinc-binding domain, present in Dystrophin, CREB-binding protein.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00291
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00291_Zinc-binding_domain,_present_in_Dystrophin,_CREB-binding_protein.


id: SM00308
description: Lipoxygenase homology 2 (beta barrel) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00308
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00308_Lipoxygenase_homology_2_(beta_barrel)_domain


id: SM00312
description: PhoX homologous domain, present in p47phox and p40phox.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00312
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00312_PhoX_homologous_domain,_present_in_p47phox_and_p40phox.


id: SM00316
description: Ribosomal protein S1-like RNA-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00316
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00316_Ribosomal_protein_S1-like_RNA-binding_domain


id: SM00317
description: SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00317
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00317_SET_(Su(var)3-9,_Enhancer-of-zeste,_Trithorax)_domain


id: SM00324
description: GTPase-activator protein for Rho-like GTPases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00324
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00324_GTPase-activator_protein_for_Rho-like_GTPases


id: SM00327
description: Von Willebrand factor (vWF) type A domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00327
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00327_Von_Willebrand_factor_(vWF)_type_A_domain


id: SM00332
description: Serine/threonine phosphatases, family 2C, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00332
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00332_Serine/threonine_phosphatases,_family_2C,_catalytic_domain


id: SM00359
description: Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00359
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00359_Putative_RNA-binding_Domain_in_PseudoUridine_synthase_and_Archaeosine_transglycosylase


id: SM00367
description: Leucine-rich repeat - CC (cysteine-containing) subfamily
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00367
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00367_Leucine-rich_repeat_-_CC_(cysteine-containing)_subfamily


id: SM00369
description: Leucine-rich repeats, typical (most populated) subfamily
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00369
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00369_Leucine-rich_repeats,_typical_(most_populated)_subfamily


id: SM00380
description: DNA-binding domain in plant proteins such as APETALA2 and EREBPs
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00380
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00380_DNA-binding_domain_in_plant_proteins_such_as_APETALA2_and_EREBPs


id: SM00382
description: ATPases associated with a variety of cellular activities
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00382
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00382_ATPases_associated_with_a_variety_of_cellular_activities


id: SM00384
description: DNA binding domain with preference for A/T rich regions
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00384
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00384_DNA_binding_domain_with_preference_for_A/T_rich_regions


id: SM00385
description: Domain present in cyclins, TFIIB and Retinoblastoma
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00385
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00385_Domain_present_in_cyclins,_TFIIB_and_Retinoblastoma


id: SM00401
description: Zinc finger binding to DNA consensus sequence [AT]GATA[AG]
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00401
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00401_Zinc_finger_binding_to_DNA_consensus_sequence_[AT]GATA[AG]


id: SM00436
description: Bacterial DNA topoisomeraes I ATP-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00436
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00436_Bacterial_DNA_topoisomeraes_I_ATP-binding_domain


id: SM00437
description: Bacterial DNA topoisomerase I DNA-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00437
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00437_Bacterial_DNA_topoisomerase_I_DNA-binding_domain


id: SM00446
description: Occurring C-terminal to leucine-rich repeats
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00446
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00446_Occurring_C-terminal_to_leucine-rich_repeats


id: SM00452
description: Soybean trypsin inhibitor (Kunitz) family of protease inhibitors
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00452
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00452_Soybean_trypsin_inhibitor_(Kunitz)_family_of_protease_inhibitors


id: SM00456
description: Domain with 2 conserved Trp (W) residues
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00456
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00456_Domain_with_2_conserved_Trp_(W)_residues


id: SM00460
description: Transglutaminase/protease-like homologues
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00460
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00460_Transglutaminase/protease-like_homologues


id: SM00464
description: Found in ATP-dependent protease La (LON)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00464
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00464_Found_in_ATP-dependent_protease_La_(LON)


id: SM00466
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00466
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00466_SET_and_RING_finger_associated_domain._Domain_of_unknown_function_in_SET_domain_containing_proteins_and_in_Deinococcus_radiodurans_DRA1533.

description:
  SET and RING finger associated domain. Domain of unknown function in SET domain containing proteins and in Deinococcus radiodurans DRA1533.


id: SM00471
description: Metal dependent phosphohydrolases with conserved HD motif.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00471
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00471_Metal_dependent_phosphohydrolases_with_conserved_HD_motif.


id: SM00472
description: Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00472
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00472_Domain_in_ryanodine_and_inositol_trisphosphate_receptors_and_protein_O-mannosyltransferases


id: SM00479
description: Exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other exonucleases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00479
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00479_Exonuclease_domain_in_DNA-polymerase_alpha_and_epsilon_chain,_ribonuclease_T_and_other_exonucleases


id: SM00493
description: Topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00493
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00493_Topoisomerases,_DnaG-type_primases,_OLD_family_nucleases_and_RecR_proteins


id: SM00499
description: Plant lipid transfer protein / seed storage protein / trypsin-alpha amylase inhibitor domain family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00499
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00499_Plant_lipid_transfer_protein_/_seed_storage_protein_/_trypsin-alpha_amylase_inhibitor_domain_family


id: SM00501
description: BRIGHT, ARID (A/T-rich interaction domain) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00501
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00501_BRIGHT,_ARID_(A/T-rich_interaction_domain)_domain


id: SM00508
description: Cysteine-rich motif following a subset of SET domains
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00508
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00508_Cysteine-rich_motif_following_a_subset_of_SET_domains


id: SM00513
description: Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00513
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00513_Putative_DNA-binding_(bihelical)_motif_predicted_to_be_involved_in_chromosomal_organisation


id: SM00515
description: Domain at the C-termini of GCD6, eIF-2B epsilon, eIF-4 gamma and eIF-5
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00515
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00515_Domain_at_the_C-termini_of_GCD6,_eIF-2B_epsilon,_eIF-4_gamma_and_eIF-5


id: SM00516
description: Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00516
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00516_Domain_in_homologues_of_a_S._cerevisiae_phosphatidylinositol_transfer_protein_(Sec14p)


id: SM00517
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00517
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00517_C-terminal_domain_of_Poly(A)-binding_protein._Present_also_in_Drosophila_hyperplastics_discs_protein.

description:
  C-terminal domain of Poly(A)-binding protein. Present also in Drosophila hyperplastics discs protein.


id: SM00525
description: Iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00525
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00525_Iron-sulpphur_binding_domain_in_DNA-(apurinic_or_apyrimidinic_site)_lyase_(subfamily_of_ENDO3)


id: SM00527
description: Domain in high mobilty group proteins HMG14 and HMG 17
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00527
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00527_Domain_in_high_mobilty_group_proteins_HMG14_and_HMG_17


id: SM00530
description: Helix-turn-helix XRE-family like proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00530
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00530_Helix-turn-helix_XRE-family_like_proteins


id: SM00533
description: DNA-binding domain of DNA mismatch repair MUTS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00533
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00533_DNA-binding_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00534
description: ATPase domain of DNA mismatch repair MUTS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00534
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00534_ATPase_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00543
description: Middle domain of eukaryotic initiation factor 4G (eIF4G)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00543
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00543_Middle_domain_of_eukaryotic_initiation_factor_4G_(eIF4G)


id: SM00544
description: Domain in DAP-5, eIF4G, MA-3 and other proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00544
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00544_Domain_in_DAP-5,_eIF4G,_MA-3_and_other_proteins.


id: SM00545
description: Small domain found in the jumonji family of transcription factors
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00545
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00545_Small_domain_found_in_the_jumonji_family_of_transcription_factors


id: SM00546
description: Domain that may be involved in binding ubiquitin-conjugating enzymes (UBCs)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00546
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00546_Domain_that_may_be_involved_in_binding_ubiquitin-conjugating_enzymes_(UBCs)


id: SM00551
description: TAZ zinc finger, present in p300 and CBP
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00551
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00551_TAZ_zinc_finger,_present_in_p300_and_CBP


id: SM00553
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00553
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00553_Domain_present_in_Saccharomyces_cerevisiae_Shp1,_Drosophila_melanogaster_eyes_closed_gene_(eyc),_and_vertebrate_p47.

description:
  Domain present in Saccharomyces cerevisiae Shp1, Drosophila melanogaster eyes closed gene (eyc), and vertebrate p47.


id: SM00554
description: Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00554
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00554_Four_repeated_domains_in_the_Fasciclin_I_family_of_proteins,_present_in_many_other_contexts.


id: SM00558
description: A domain family that is part of the cupin metalloenzyme superfamily.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00558
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00558_A_domain_family_that_is_part_of_the_cupin_metalloenzyme_superfamily.


id: SM00559
description: Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00559
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00559_Ku70_and_Ku80_are_70kDa_and_80kDa_subunits_of_the_Lupus_Ku_autoantigen


id: SM00562
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00562
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00562_These_are_enzymes_that_catalyze_nonsubstrate_specific_conversions_of_nucleoside_diphosphates_to_nucleoside_triphosphates._These_enzymes_play_important_roles_in_bacterial_growth,_signal_transduction_and_pathogenicity.

description:
  These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.


id: SM00568
description: Domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00568
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00568_Domain_in_glucosyltransferases,_myotubularins_and_other_putative_membrane-associated_proteins


id: SM00571
description: Domain in different transcription and chromosome remodeling factors
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00571
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00571_Domain_in_different_transcription_and_chromosome_remodeling_factors


id: SM00576
description: Bromodomain transcription factors and PHD domain containing proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00576
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00576_Bromodomain_transcription_factors_and_PHD_domain_containing_proteins


id: SM00577
description: Catalytic domain of ctd-like phosphatases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00577
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00577_Catalytic_domain_of_ctd-like_phosphatases


id: SM00579
description: Domain in FBox and BRCT domain containing plant proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00579
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00579_Domain_in_FBox_and_BRCT_domain_containing_plant_proteins


id: SM00580
description: Domain in protein kinases, N-glycanases and other nuclear proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00580
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00580_Domain_in_protein_kinases,_N-glycanases_and_other_nuclear_proteins


id: SM00581
description: Proline-rich domain in spliceosome associated proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00581
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00581_Proline-rich_domain_in_spliceosome_associated_proteins


id: SM00582
description: Domain present in proteins, which are involved in regulation of nuclear pre-mRNA
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00582
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00582_Domain_present_in_proteins,_which_are_involved_in_regulation_of_nuclear_pre-mRNA


id: SM00584
description: Domain in TBC and LysM domain containing proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00584
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00584_Domain_in_TBC_and_LysM_domain_containing_proteins


id: SM00591
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00591
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00591_Domain_in_RING_finger_and_WD_repeat_containing_proteins_and_DEXDc-like_helicases_subfamily_related_to_the_UBCc_domain

description:
  Domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain


id: SM00597
description: Zinc finger in transposases and transcription factors
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00597
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00597_Zinc_finger_in_transposases_and_transcription_factors


id: SM00648
description: Suppressor-of-White-APricot splicing regulator
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00648
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00648_Suppressor-of-White-APricot_splicing_regulator


id: SM00652
description: Eukaryotic translation initiation factor 1A
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00652
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00652_Eukaryotic_translation_initiation_factor_1A


id: SM00653
description: Domain present in translation initiation factor eIF2B and eIF5
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00653
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00653_Domain_present_in_translation_initiation_factor_eIF2B_and_eIF5


id: SM00664
description: Possible catecholamine-binding domain present in a variety of eukaryotic proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00664
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00664_Possible_catecholamine-binding_domain_present_in_a_variety_of_eukaryotic_proteins.


id: SM00665
description: Cytochrome b-561 / ferric reductase transmembrane domain.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00665
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00665_Cytochrome_b-561_/_ferric_reductase_transmembrane_domain.


id: SM00667
description: Lissencephaly type-1-like homology motif
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00667
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00667_Lissencephaly_type-1-like_homology_motif


id: SM00670
description: Large family of predicted nucleotide-binding domains
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00670
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00670_Large_family_of_predicted_nucleotide-binding_domains


id: SM00672
description: Putative lipopolysaccharide-modifying enzyme.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00672
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00672_Putative_lipopolysaccharide-modifying_enzyme.


id: SM00673
description: Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00673
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00673_Domain_in_CAPs_(cyclase-associated_proteins)_and_X-linked_retinitis_pigmentosa_2_gene_product.


id: SM00679
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00679
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00679_Repeated_motif_present_between_transmembrane_helices_in_cystinosin,_yeast_ERS1p,_mannose-P-dolichol_utilization_defect_1,_and_other_hypothetical_proteins.

description:
  Repeated motif present between transmembrane helices in cystinosin, yeast ERS1p, mannose-P-dolichol utilization defect 1, and other hypothetical proteins.


id: SM00684
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00684
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00684_Tandem_repeat_in_fly_CG14066_(La_related_protein),_human_KIAA0731_and_worm_R144.7._Unknown_function.

description:
  Tandem repeat in fly CG14066 (La related protein), human KIAA0731 and worm R144.7. Unknown function.


id: SM00695
description: Domain in ubiquitin-specific proteases.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00695
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00695_Domain_in_ubiquitin-specific_proteases.


id: SM00698
description: Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00698
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00698_Possible_plasma_membrane-binding_motif_in_junctophilins,_PIP-5-kinases_and_protein_kinases.


id: SM00702
description: Prolyl 4-hydroxylase alpha subunit homologues.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00702
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00702_Prolyl_4-hydroxylase_alpha_subunit_homologues.


id: SM00709
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00709
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00709_Duplicated_domain_in_the_epidermal_growth_factor-_and_elongation_factor-1alpha-binding_protein_Zpr1._Also_present_in_archaeal_proteins.

description:
  Duplicated domain in the epidermal growth factor- and elongation factor-1alpha-binding protein Zpr1. Also present in archaeal proteins.


id: SM00714
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00714
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00714_Possible_membrane-associated_motif_in_LPS-induced_tumor_necrosis_factor_alpha_factor_(LITAF),_also_known_as_PIG7,_and_other_animal_proteins.

description:
  Possible membrane-associated motif in LPS-induced tumor necrosis factor alpha factor (LITAF), also known as PIG7, and other animal proteins.


id: SM00715
description: Domain in the RNA-binding Lupus La protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00715
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00715_Domain_in_the_RNA-binding_Lupus_La_protein


id: SM00717
description: SANT SWI3, ADA2, N-CoR and TFIIIB DNA-binding domains
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00717
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00717_SANT__SWI3,_ADA2,_N-CoR_and_TFIIIB_DNA-binding_domains


id: SM00719
description: Short conserved domain in transcriptional regulators.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00719
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00719_Short_conserved_domain_in_transcriptional_regulators.


id: SM00729
description: Elongator protein 3, MiaB family, Radical SAM
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00729
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00729_Elongator_protein_3,_MiaB_family,_Radical_SAM


id: SM00730
description: Presenilin, signal peptide peptidase, family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00730
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00730_Presenilin,_signal_peptide_peptidase,_family


id: SM00733
description: Mitochondrial termination factor repeats
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00733
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00733_Mitochondrial_termination_factor_repeats


id: SM00737
description: Domain involved in innate immunity and lipid metabolism.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00737
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00737_Domain_involved_in_innate_immunity_and_lipid_metabolism.


id: SM00738
description: In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00738
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00738_In_Spt5p,_this_domain_may_confer_affinity_for_Spt4p._It_possesses_a_RNP-like_fold.


id: SM00743
description: Tudor-like domain present in plant sequences.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00743
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00743_Tudor-like_domain_present_in_plant_sequences.


id: SM00744
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00744
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00744_The_RING-variant_domain_is_a_C4HC3_zinc-finger_like_motif_found_in_a_number_of_cellular_and_viral_proteins._Some_of_these_proteins_have_been_shown_both_in_vivo_and_in_vitro_to_have_ubiquitin_E3_ligase_activity.

description:
  The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.


id: SM00751
description: Domain in transcription factors and synapse-associated proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00751
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00751_Domain_in_transcription_factors_and_synapse-associated_proteins


id: SM00756
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00756
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00756_Family_of_likely_enzymes_that_includes_the_catalytic_subunit_of_vitamin_K_epoxide_reductase._Bacterial_homologues_are_fused_to_members_of_the_thioredoxin_family_of_oxidoreductases.

description:
  Family of likely enzymes that includes the catalytic subunit of vitamin K epoxide reductase. Bacterial homologues are fused to members of the thioredoxin family of oxidoreductases.


id: SM00767
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00767
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00767_DCD_is_a_plant_specific_domain_in_proteins_involved_in_development_and_programmed_cell_death._The_domain_is_shared_by_several_proteins_in_the_Arabidopsis_and_the_rice_genomes,_which_otherwise_show_a_different_protein_architecture._Biological_studies_...

description:
  DCD is a plant specific domain in proteins involved in development and programmed cell death. The domain is shared by several proteins in the Arabidopsis and the rice genomes, which otherwise show a different protein architecture. Biological studies ...


id: SM00768
description: Possibly involved in carbohydrate binding
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00768
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00768_Possibly_involved_in_carbohydrate_binding


id: SM00769
description: Water Stress and Hypersensitive response
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00769
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00769_Water_Stress_and_Hypersensitive_response


id: SM00775
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00775
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00775_This_domain_is_found_in_Saccharomyces_cerevisiae_protein_SMP2,_proteins_with_an_N-terminal_lipin_domain_and_phosphatidylinositol_transfer_proteins._SMP2_is_involved_in_plasmid_maintenance_and_respiration._Lipin_proteins_are_involved_in_adipose_tissue_...

description:
  This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins. SMP2 is involved in plasmid maintenance and respiration. Lipin proteins are involved in adipose tissue ...


id: SM00777
description: Mad3/BUB1 hoMad3/BUB1 homology region 1
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00777
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00777_Mad3/BUB1_hoMad3/BUB1_homology_region_1


id: SM00799
description: Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00799
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00799_Domain_found_in_a_variety_of_signalling_proteins,_always_encircled_by_uDENN_and_dDENN


id: SM00800
description: Domain always found upstream of DENN domain, found in a variety of signalling proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00800
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00800_Domain_always_found_upstream_of_DENN_domain,_found_in_a_variety_of_signalling_proteins


id: SM00801
description: Domain always found downstream of DENN domain, found in a variety of signalling proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00801
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00801_Domain_always_found_downstream_of_DENN_domain,_found_in_a_variety_of_signalling_proteins


id: SM00802
description: Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00802
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00802_Domain_in_UVSB_PI-3_kinase,_MEI-41_and_ESR-1


id: SM00803
description: TATA box binding protein associated factor
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00803
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00803_TATA_box_binding_protein_associated_factor


id: SM00810
description: Alpha-amylase C-terminal beta-sheet domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00810
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00810_Alpha-amylase_C-terminal_beta-sheet_domain


id: SM00833
description: Cobalamin synthesis protein cobW C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00833
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00833_Cobalamin_synthesis_protein_cobW_C-terminal_domain


id: SM00837
description: Rare lipoprotein A (RlpA)-like double-psi beta-barrel
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00837
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00837_Rare_lipoprotein_A_(RlpA)-like_double-psi_beta-barrel


id: SM00839
description: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00839
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00839_Glutamate/Leucine/Phenylalanine/Valine_dehydrogenase


id: SM00840
description: This DALR domain is found in cysteinyl-tRNA-synthetases.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00840
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00840_This_DALR_domain_is_found_in_cysteinyl-tRNA-synthetases.


id: SM00846
description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00846
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00846_Glyceraldehyde_3-phosphate_dehydrogenase,_NAD_binding_domain


id: SM00847
description: Helicase associated domain (HA2) Add an annotation
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00847
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00847_Helicase_associated_domain_(HA2)__Add_an_annotation


id: SM00848
description: Cathepsin propeptide inhibitor domain (I29)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00848
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00848_Cathepsin_propeptide_inhibitor_domain_(I29)


id: SM00856
description: Plant invertase/pectin methylesterase inhibitor
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00856
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00856_Plant_invertase/pectin_methylesterase_inhibitor


id: SM00859
description: Semialdehyde dehydrogenase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00859
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00859_Semialdehyde_dehydrogenase,_NAD_binding_domain


id: SM00861
description: Transketolase, pyrimidine binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00861
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00861_Transketolase,_pyrimidine_binding_domain


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00876
description: Biotin and Thiamin Synthesis associated domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00876
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00876_Biotin_and_Thiamin_Synthesis_associated_domain


id: SM00879
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00879
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00879_The_Brix_domain_is_found_in_a_number_of_eukaryotic_proteins_including_SSF_proteins_from_yeast_and_humans,_Arabidopsis_thaliana_Peter_Pan-like_protein_and_several_hypothetical_proteins.

description:
  The Brix domain is found in a number of eukaryotic proteins including SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.


id: SM00888
description: EF-1 guanine nucleotide exchange domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00888
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00888_EF-1_guanine_nucleotide_exchange_domain


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00898
description: Formamidopyrimidine-DNA glycosylase N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00898
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00898_Formamidopyrimidine-DNA_glycosylase_N-terminal_domain


id: SM00910
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00910
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00910_The_HIRAN_protein_(HIP116,_Rad5p_N-terminal)_is_found_in_the_N-terminal_regions_of_the_SWI2/SNF2_proteins_typified_by_HIP116_and_Rad5p._HIRAN_is_found_as_a_standalone_protein_in_several_bacteria_and_prophages,_or_fused_to_other_catalytic_domains,_...

description:
  The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, ...


id: SM00916
description: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00916
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00916_Mitochondrial_ribosomal_protein_L51_/_S25_/_CI-B8_domain


id: SM00922
description: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00922
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00922_Mandelate_racemase_/_muconate_lactonizing_enzyme,_C-terminal_domain


id: SM00928
description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00928
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00928_NADH-ubiquinone_oxidoreductase-F_iron-sulfur_binding_region


id: SM00929
description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00929
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00929_NADH-ubiquinone_oxidoreductase-G_iron-sulfur_binding_region


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00948
description: Proteasome subunit A N-terminal signature Add an annotation
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00948
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00948_Proteasome_subunit_A_N-terminal_signature__Add_an_annotation


id: SM00949
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00949
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00949_This_domain_is_named_PAZ_after_the_proteins_Piwi_Argonaut_and_Zwille._This_domain_is_found_in_two_families_of_proteins_that_are_involved_in_post-transcriptional_gene_silencing._These_are_the_Piwi_family_and_the_Dicer_family,_that_includes_the_Carpel_...

description:
  This domain is named PAZ after the proteins Piwi Argonaut and Zwille. This domain is found in two families of proteins that are involved in post-transcriptional gene silencing. These are the Piwi family and the Dicer family, that includes the Carpel ...


id: SM00950
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00950
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00950_This_domain_is_found_in_the_protein_Piwi_and_its_relatives._The_function_of_this_domain_is_the_dsRNA_guided_hydrolysis_of_ssRNA._Determination_of_the_crystal_structure_of_Argonaute_reveals_that_PIWI_is_an_RNase_H_domain,_and_identifies_Argonaute_as_...

description:
  This domain is found in the protein Piwi and its relatives. The function of this domain is the dsRNA guided hydrolysis of ssRNA. Determination of the crystal structure of Argonaute reveals that PIWI is an RNase H domain, and identifies Argonaute as ...


id: SM00951
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00951
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00951_QLQ_is_named_after_the_conserved_Gln,_Leu,_Gln_motif._QLQ_is_found_at_the_N-terminus_of_SWI2/SNF2_protein,_which_has_been_shown_to_be_involved_in_protein-protein_interactions._QLQ_has_been_postulated_to_be_involved_in_mediating_protein_interactions_...

description:
  QLQ is named after the conserved Gln, Leu, Gln motif. QLQ is found at the N-terminus of SWI2/SNF2 protein, which has been shown to be involved in protein-protein interactions. QLQ has been postulated to be involved in mediating protein interactions ...


id: SM00952
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00952
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00952_This_domain_is_found_in_various_eukaryotic_species,_particularly_in_apicomplexans_such_as_Plasmodium_falciparum,_where_it_is_found_in_proteins_that_are_important_in_various_parasite-host_cell_interactions._It_is_thought_to_be_an_RNA-binding_domain_...

description:
  This domain is found in various eukaryotic species, particularly in apicomplexans such as Plasmodium falciparum, where it is found in proteins that are important in various parasite-host cell interactions. It is thought to be an RNA-binding domain ...


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00959
description: Rho termination factor, N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00959
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00959_Rho_termination_factor,_N-terminal_domain


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00975
description: Telomerase ribonucleoprotein complex - RNA binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00975
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00975_Telomerase_ribonucleoprotein_complex_-_RNA_binding_domain


id: SM00976
description: Telomeric single stranded DNA binding POT1/CDC13
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00976
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00976_Telomeric_single_stranded_DNA_binding_POT1/CDC13


id: SM00978
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00978
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00978_Tim44_is_an_essential_component_of_the_machinery_that_mediates_the_translocation_of_nuclear-encoded_proteins_across_the_mitochondrial_inner_membrane_PUBMED:10430866._Tim44_is_thought_to_bind_phospholipids_of_the_mitochondrial_inner_membrane_both_by_...

description:
  Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane PUBMED:10430866. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by ...


id: SM00979
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00979
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00979_This_short_possible_domain_is_found_in_a_variety_of_plant_transcription_factors_that_contain_GATA_domains_as_well_as_other_motifs._Although_previously_known_as_the_Zim_domain_this_is_now_called_the_tify_domain_after_its_most_conserved_amino_acids._...

description:
  This short possible domain is found in a variety of plant transcription factors that contain GATA domains as well as other motifs. Although previously known as the Zim domain this is now called the tify domain after its most conserved amino acids. ...


id: SM00982
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00982
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00982_This_domain_is_found_in_proteins_necessary_for_strand-specific_repair_in_DNA_such_as_TRCF_in_Escherichia_coli._A_lesion_in_the_template_strand_blocks_the_RNA_polymerase_complex_(RNAP)._The_RNAP-DNA-RNA_complex_is_specifically_recognised_by_the_...

description:
  This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the ...


id: SM00983
description: Thiamin pyrophosphokinase, vitamin B1 binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00983
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00983_Thiamin_pyrophosphokinase,_vitamin_B1_binding_domain


id: SM00985
description: Ubiquitin-activating enzyme e1 C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00985
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00985_Ubiquitin-activating_enzyme_e1_C-terminal_domain


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00990
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00990
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00990_This_entry_contains_proteins_with_the_VRR-NUC_domain._It_is_associated_with_members_of_the_PD-(D/E)XK_nuclease_superfamily,_which_include_the_type_III_restriction_modification_enzymes,_for_example_StyLTI.

description:
  This entry contains proteins with the VRR-NUC domain. It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes, for example StyLTI.


id: SM00991
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00991
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00991_A_conserved_domain_of_46_amino_acids,_called_WHEP-TRS_has_been_shown_PUBMED:1756734_to_exist_in_a_number_of_higher_eukaryote_aminoacyl-transfer_RNA_synthetases._This_domain_is_present_one_to_six_times_in_the_several_enzymes._There_are_three_copies_in_...

description:
  A conserved domain of 46 amino acids, called WHEP-TRS has been shown PUBMED:1756734 to exist in a number of higher eukaryote aminoacyl-transfer RNA synthetases. This domain is present one to six times in the several enzymes. There are three copies in ...


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01008
description: Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01008
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01008_Aldehyde_oxidase_and_xanthine_dehydrogenase,_a/b_hammerhead_domain


id: SM01010
description: 5-AMP-activated protein kinase beta subunit, interation domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01010
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01010_5-AMP-activated_protein_kinase_beta_subunit,_interation_domain


id: SM01013
description: Anaphase promoting complex (APC) subunit 2
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01013
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01013_Anaphase_promoting_complex_(APC)_subunit_2


id: SM01020
description: Beta2-adaptin appendage, C-terminal sub-domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01020
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01020_Beta2-adaptin_appendage,_C-terminal_sub-domain


id: SM01022
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01022
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01022_The_ASCH_domain_adopts_a_beta-barrel_fold_similar_to_that_of_the_PUA_domain._It_is_thought_to_function_as_an_RNA-binding_domain_during_coactivation,_RNA-processing_and_possibly_during_prokaryotic_translation_regulation_PUBMED:16322048.

description:
  The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain. It is thought to function as an RNA-binding domain during coactivation, RNA-processing and possibly during prokaryotic translation regulation PUBMED:16322048.


id: SM01050
description: Cactus-binding C-terminus of cactin protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01050
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01050_Cactus-binding_C-terminus_of_cactin_protein


id: SM01052
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01052
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01052_Cytoskeleton-associated_proteins_(CAPs)_are_involved_in_the_organisation_of_microtubules_and_transportation_of_vesicles_and_organelles_along_the_cytoskeletal_network._A_conserved_motif,_CAP-Gly,_has_been_identified_in_a_number_of_CAPs,_including_...

description:
  Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including ...


id: SM01060
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01072
description: Cell division protein 48 (CDC48) domain 2
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01072
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01072_Cell_division_protein_48_(CDC48)_domain_2


id: SM01073
description: Cell division protein 48 (CDC48) N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01073
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01073_Cell_division_protein_48_(CDC48)_N-terminal_domain


id: SM01076
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01076
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01076_CG-1_domains_are_highly_conserved_domains_of_about_130_amino-acid_residues_containing_a_predicted_bipartite_NLS_and_named_after_a_partial_cDNA_clone_isolated_from_parsley_encoding_a_sequence-specific_DNA-binding_protein_PUBMED:8075408._CG-1_domains_...

description:
  CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein PUBMED:8075408. CG-1 domains ...


id: SM01079
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01079
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01079_This_domain_is_found_in_the_extracellular_portion_of_receptor-like_proteins_-_such_as_serine/threonine_kinases_and_adenylyl_cyclases_PUBMED:11590000,_PUBMED:11590001._Predicted_to_be_a_ligand_binding_domain_PUBMED:11590000.

description:
  This domain is found in the extracellular portion of receptor-like proteins - such as serine/threonine kinases and adenylyl cyclases PUBMED:11590000, PUBMED:11590001. Predicted to be a ligand binding domain PUBMED:11590000.


id: SM01083
description: N-terminal domain of CBF1 interacting co-repressor CIR
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01083
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01083_N-terminal_domain_of_CBF1_interacting_co-repressor_CIR


id: SM01084
description: Cyclin-dependent kinase regulatory subunit
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01084
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01084_Cyclin-dependent_kinase_regulatory_subunit


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01092
description: CO dehydrogenase flavoprotein C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01092
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01092_CO_dehydrogenase_flavoprotein_C-terminal_domain


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01098
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01098
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01098_This_is_the_C-terminal_conserved_region_of_the_pre-mRNA_3-end-processing_of_the_polyadenylation_factor_CPSF-73/CPSF-100_proteins._The_exact_function_of_this_domain_is_not_known.

description:
  This is the C-terminal conserved region of the pre-mRNA 3-end-processing of the polyadenylation factor CPSF-73/CPSF-100 proteins. The exact function of this domain is not known.


id: SM01103
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01103
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01103_Escherichia_coli_YhbY_is_associated_with_pre-50S_ribosomal_subunits,_which_implies_a_function_in_ribosome_assembly._GFP_fused_to_a_single-domain_CRM_protein_from_maize_localises_to_the_nucleolus,_suggesting_that_an_analogous_activity_may_have_been_...

description:
  Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly. GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been ...


id: SM01115
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01115
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01115_The_cwf21_family_is_involved_in_mRNA_splicing._It_has_been_isolated_as_a_subcomplex_of_the_splicosome_in_Schizosaccharomyces_pombe_(PUBMED:11884590)._The_function_of_the_cwf21_domain_is_to_bind_directly_to_the_spliceosomal_protein_Prp8._Mutations_in_...

description:
  The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe (PUBMED:11884590). The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in ...


id: SM01116
description: Cyanate lyase C-terminal domain, Cyanate hydratase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01116
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01116_Cyanate_lyase_C-terminal_domain,_Cyanate_hydratase


id: SM01117
description: Cytochrome b5-like Heme/Steroid binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01117
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01117_Cytochrome_b5-like_Heme/Steroid_binding_domain


id: SM01120
description: This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01120
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01120_This_domain_is_the_predicted_phosphatase_domain_of_the_dihydroxyacetone_kinase_family.


id: SM01122
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01122
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01122_DBC1_and_it_homologs_from_diverse_eukaryotes_are_a_catalytically_inactive_version_of_the_Nudix_hydrolase_(MutT)_domain_(PUBMED:18418069)._DBC1_is_predicted_to_bind_NAD_metabolites_and_regulate_the_activity_of_SIRT1_or_related_deacetylases_by_sensing_...

description:
  DBC1 and it homologs from diverse eukaryotes are a catalytically inactive version of the Nudix hydrolase (MutT) domain (PUBMED:18418069). DBC1 is predicted to bind NAD metabolites and regulate the activity of SIRT1 or related deacetylases by sensing ...


id: SM01124
description: Lariat debranching enzyme, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01124
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01124_Lariat_debranching_enzyme,_C-terminal_domain


id: SM01127
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01127
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01127_The_DDHD_domain_is_180_residues_long_and_contains_four_conserved_residues_that_may_form_a_metal_binding_site._The_domain_is_named_after_these_four_residues._This_pattern_of_conservation_of_metal_binding_residues_is_often_seen_in_phosphoesterase_...

description:
  The DDHD domain is 180 residues long and contains four conserved residues that may form a metal binding site. The domain is named after these four residues. This pattern of conservation of metal binding residues is often seen in phosphoesterase ...


id: SM01128
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01128
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01128_This_is_a_family_of_proteins_of_approximately_300_residues,_found_in_plants_and_vertebrates._They_contain_a_highly_conserved_DDRGK_motif.

description:
  This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


id: SM01129
description: Transcriptional regulator DELLA protein N terminal
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01129
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01129_Transcriptional_regulator_DELLA_protein_N_terminal


id: SM01135
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01135
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01135_DIRP_(Domain_in_Rb-related_Pathway)_is_postulated_to_be_involved_in_the_Rb-related_pathway,_which_is_encoded_by_multiple_eukaryotic_genomes_and_is_present_in_proteins_including_lin-9_of_Caenorhabditis_elegans,_aly_of_fruit_fly_and_mustard_weed._...

description:
  DIRP (Domain in Rb-related Pathway) is postulated to be involved in the Rb-related pathway, which is encoded by multiple eukaryotic genomes and is present in proteins including lin-9 of Caenorhabditis elegans, aly of fruit fly and mustard weed. ...


id: SM01142
description: This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases [PUBMED:15112237].
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01142
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01142_This_C_terminal_domain_is_found_in_DOB1/SK12/helY-like_DEAD_box_helicases_[PUBMED:15112237].


id: SM01144
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01144
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01144_This_presumed_domain_is_found_in_bacterial_and_eukaryotic_proteins._Its_function_is_unknown._The_domain_contains_multiple_conserved_motifs_including_a_DTXW_motif_that_this_domain_has_been_named_after.

description:
  This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.


id: SM01156
description: Eukaryotic domain of unknown function (DUF1716)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01156
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01156_Eukaryotic_domain_of_unknown_function_(DUF1716)


id: SM01157
description: This is a domain of unknown function. It may have a role in ATPase activation.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01157
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01157_This_is_a_domain_of_unknown_function._It_may_have_a_role_in_ATPase_activation.


id: SM01159
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01159
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01159_This_domain_is_found_on_the_epsilon_catalytic_subunit_of_DNA_polymerase._It_is_found_C_terminal_to_POLBc_(SM00486).

description:
  This domain is found on the epsilon catalytic subunit of DNA polymerase. It is found C terminal to POLBc (SM00486).


id: SM01160
description: Eukaryotic integral membrane protein (DUF1751)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01160
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01160_Eukaryotic_integral_membrane_protein_(DUF1751)


id: SM01162
description: This domain is always found adjacent to SMR (SM00463).
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01162
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01162_This_domain_is_always_found_adjacent_to_SMR_(SM00463).


id: SM01163
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01163
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01163_This_region_is_found_in_argonaute_[PUBMED:16216572]_proteins_and_often_co-occurs_with_BAG_(SM00264)_and_Piwi_(SM00950).

description:
  This region is found in argonaute [PUBMED:16216572] proteins and often co-occurs with BAG (SM00264) and Piwi (SM00950).


id: SM01172
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01172
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01172_This_domain_family_is_found_in_eukaryotes,_and_is_approximately_120_amino_acids_in_length._There_are_two_conserved_sequence_motifs:_YGL_and_LRDR._This_family_is_related_to_GATase_enzyme_domains.

description:
  This domain family is found in eukaryotes, and is approximately 120 amino acids in length. There are two conserved sequence motifs: YGL and LRDR. This family is related to GATase enzyme domains.


id: SM01173
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01173
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01173_This_family_is_found_at_the_very_C-terminus_of_proteins_that_carry_a_G-patch_domain_SM00443._The_domain_is_short_and_cysteine-rich_.

description:
  This family is found at the very C-terminus of proteins that carry a G-patch domain SM00443. The domain is short and cysteine-rich .


id: SM01174
description: The proteins in this family are uncharacterized but often named FAM188B.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01174
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01174_The_proteins_in_this_family_are_uncharacterized_but_often_named_FAM188B.


id: SM01175
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01175
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01175_This_is_a_family_of_cysteine-rich_proteins._Many_members_also_carry_a_pleckstrin-homology_domain,SM00233.

description:
  This is a family of cysteine-rich proteins. Many members also carry a pleckstrin-homology domain,SM00233.


id: SM01177
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01177
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01177_This_short_domain_is_found_in_fungi,_plants_and_animals,_and_the_proteins_appear_to_be_necessary_for_chromosome_segregation_during_meiosis.

description:
  This short domain is found in fungi, plants and animals, and the proteins appear to be necessary for chromosome segregation during meiosis.


id: SM01178
description: This short domain is found at the C-terminus of many helicase proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01178
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01178_This_short_domain_is_found_at_the_C-terminus_of_many_helicase_proteins.


id: SM01180
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01180
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01180_DWNN_is_a_ubiquitin_like_domain_found_at_the_N-terminus_of_the_RBBP6_family_of_splicing-associated_proteins_PUBMED:16396680._The_DWNN_domain_is_independently_expressed_in_higher_vertebrates_so_it_may_function_as_a_novel_ubiquitin-like_modifier_of_...

description:
  DWNN is a ubiquitin like domain found at the N-terminus of the RBBP6 family of splicing-associated proteins PUBMED:16396680. The DWNN domain is independently expressed in higher vertebrates so it may function as a novel ubiquitin-like modifier of ...


id: SM01181
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01181
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01181_E1_and_E2_enzymes_play_a_central_role_in_ubiquitin_and_ubiquitin-like_protein_transfer_cascades._This_is_an_E2_binding_domain_that_is_found_on_NEDD8_activating_E1_enzyme._The_domain_resembles_ubiquitin,_and_recruits_the_catalytic_core_of_the_E2_...

description:
  E1 and E2 enzymes play a central role in ubiquitin and ubiquitin-like protein transfer cascades. This is an E2 binding domain that is found on NEDD8 activating E1 enzyme. The domain resembles ubiquitin, and recruits the catalytic core of the E2 ...


id: SM01183
description: Elongation factor 1 gamma, conserved domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01183
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01183_Elongation_factor_1_gamma,_conserved_domain


id: SM01188
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01188
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01188_This_domain_is_required_for_the_nuclear_localisation_of_these_proteins_PUBMED:11352458._All_of_these_proteins_are_members_of_the_Tale/Knox_homeodomain_family,_a_subfamily_within_homeobox_SM00389.

description:
  This domain is required for the nuclear localisation of these proteins PUBMED:11352458. All of these proteins are members of the Tale/Knox homeodomain family, a subfamily within homeobox SM00389.


id: SM01189
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01189
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01189_The_ELM2_(Egl-27_and_MTA1_homology_2)_domain_is_a_small_domain_of_unknown_function._It_is_found_in_the_MTA1_protein_that_is_part_of_the_NuRD_complex_PUBMED:10226007._The_domain_is_usually_found_to_the_N_terminus_of_a_myb-like_DNA_binding_domain_SANT_...

description:
  The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex PUBMED:10226007. The domain is usually found to the N terminus of a myb-like DNA binding domain SANT ...


id: SM01191
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01191
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01191_This_presumed_domain_is_named_after_Emsy_N_Terminus_(ENT)._Emsy_is_a_protein_that_is_amplified_in_breast_cancer_and_interacts_with_BRCA2._The_N_terminus_of_this_protein_is_found_to_be_similar_to_other_vertebrate_and_plant_proteins_of_unknown_...

description:
  This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown ...


id: SM01194
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01194
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01194_The_release_factor_eRF1_terminates_protein_biosynthesis_by_recognising_stop_codons_at_the_A_site_of_the_ribosome_and_stimulating_peptidyl-tRNA_bond_hydrolysis_at_the_peptidyl_transferase_centre._The_crystal_structure_of_human_eRF1_is_known_...

description:
  The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known ...


id: SM01199
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01199
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01199_The_FDF_domain,_so_called_because_of_the_conserved_FDF_at_its_N_termini,_is_an_entirely_alpha-helical_domain_with_multiple_exposed_hydrophilic_loops._It_is_found_at_the_C_terminus_of_Scd6p-like_SM_domains._It_is_also_found_with_other_divergent_Sm_...

description:
  The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C terminus of Scd6p-like SM domains. It is also found with other divergent Sm ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01214
description: RNA pol II promoter Fmp27 protein domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01214
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01214_RNA_pol_II_promoter_Fmp27_protein_domain


id: SM01218
description: C-terminal duplication domain of Friend of PRMT1
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01218
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01218_C-terminal_duplication_domain_of_Friend_of_PRMT1


id: SM01222
description: Formiminotransferase domain, N-terminal subdomain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01222
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01222_Formiminotransferase_domain,_N-terminal_subdomain


id: SM01227
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01227
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01227_This_domain_is_found_in_proteins_carrying_other_domains_known_to_be_involved_in_intracellular_signalling_pathways_indicating_that_it_might_also_be_involved_in_these_pathways._It_has_4_highly_conserved_cysteine_residues,_suggesting_that_it_can_bind_...

description:
  This domain is found in proteins carrying other domains known to be involved in intracellular signalling pathways indicating that it might also be involved in these pathways. It has 4 highly conserved cysteine residues, suggesting that it can bind ...


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01238
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01238
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01238_This_domain_is_found_in_fungal_proteins_and_contains_a_conserved_IGR_motif._Its_function_is_unknown.

description:
  This domain is found in fungal proteins and contains a conserved IGR motif. Its function is unknown.


id: SM01253
description: Domain of Kin17 curved DNA-binding protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01253
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01253_Domain_of_Kin17_curved_DNA-binding_protein


id: SM01255
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01255
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01255_The_MEINOX_region_is_comprised_of_two_domains,_KNOX1_and_KNOX2._KNOX1_plays_a_role_in_suppressing_target_gene_expression._KNOX2,_essential_for_function,_is_thought_to_be_necessary_for_homo-dimerisation_PUBMED:11549765.

description:
  The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerisation PUBMED:11549765.


id: SM01256
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01256
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01256_The_MEINOX_region_is_comprised_of_two_domains,_KNOX1_and_KNOX2._KNOX1_plays_a_role_in_suppressing_target_gene_expression._KNOX2,_essential_for_function,_is_thought_to_be_necessary_for_homo-dimerisation_PUBMED:11549765.

description:
  The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerisation PUBMED:11549765.


id: SM01272
description: This domain is found associated with Lsm domain PMID:16115810.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01272
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01272_This_domain_is_found_associated_with_Lsm_domain_PMID:16115810.


id: SM01281
description: Transcription mediator complex subunit Med12
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01281
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01281_Transcription_mediator_complex_subunit_Med12


id: SM01283
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01283
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01283_This_domain_is_found_both_alone_and_at_the_C-terminus_of_actin-binding_Rho-activating_protein_(ABRA)._It_binds_to_actin,_and_in_muscle_regulates_the_actin_cytoskeleton_and_cell_motility_PMID:11983702,_20940261._It_has_a_winged_helix-like_fold_...

description:
  This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility PMID:11983702, 20940261. It has a winged helix-like fold ...


id: SM01285
description: FACT complex subunit SPT16 N-terminal lobe domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01285
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01285_FACT_complex_subunit_SPT16_N-terminal_lobe_domain


id: SM01296
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01296
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01296_This_family_features_sequences_that_are_similar_to_a_region_of_hypothetical_yeast_gene_product_N2227._This_is_thought_to_be_expressed_during_meiosis_and_may_be_involved_in_the_defence_response_to_stressful_conditions_PMID:8771715.

description:
  This family features sequences that are similar to a region of hypothetical yeast gene product N2227. This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions PMID:8771715.


id: SM01313
description: Exocyst complex component SEC3 N-terminal PIP2 binding PH
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01313
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01313_Exocyst_complex_component_SEC3_N-terminal_PIP2_binding_PH


id: SM01314
description: Snf2-ATP coupling, chromatin remodelling complex
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01314
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01314_Snf2-ATP_coupling,_chromatin_remodelling_complex


id: SM01326
description: C2 domain of PTEN tumour-suppressor protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01326
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01326_C2_domain_of_PTEN_tumour-suppressor_protein


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01332
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01332
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01332_Cyclins_are_a_family_of_proteins_that_control_the_progression_of_cells_through_the_cell_cycle_by_activating_cyclin-dependent_kinase_(Cdk)_enzymes.

description:
  Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.


id: SM01335
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01335
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01335_This_domain_is_found_in_poly(ADP-ribose)-synthetases_(PMID:15112237)._The_function_of_this_domain_is_unknown.

description:
  This domain is found in poly(ADP-ribose)-synthetases (PMID:15112237). The function of this domain is unknown.


id: SM01336
description: Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01336
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01336_Poly(ADP-ribose)_polymerase_and_DNA-Ligase_Zn-finger_region


id: SM01337
description: Anaphase-promoting complex, subunit 10 (APC10)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01337
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01337_Anaphase-promoting_complex,_subunit_10_(APC10)


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01341
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01341
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01341_Members_of_this_family_adopt_a_secondary_structure_consisting_of_a_pair_of_long,_antiparallel_alpha-helices_(the_stem)_that_support_a_three-helix_bundle_(3HB)_at_their_end._The_3HB_contains_a_helix-turn-helix_motif_and_is_similar_to_the_DNA_binding_...

description:
  Members of this family adopt a secondary structure consisting of a pair of long, antiparallel alpha-helices (the stem) that support a three-helix bundle (3HB) at their end. The 3HB contains a helix-turn-helix motif and is similar to the DNA binding ...


id: SM01343
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01343
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01343_The_FATC_domain_is_named_after_FRAP,_ATM,_TRRAP_C-terminal_(PMID:10782091)._The_solution_structure_of_the_FATC_domain_suggests_it_plays_a_role_in_redox-dependent_structural_and_cellular_stability_(PMID:15772072).

description:
  The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072).


id: SM01349
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01349
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01349_XMAP215/Dis1_proteins,_such_as_Alp14_and_XMAP215,_increase_microtubules_dynamic_polymerization_rates_by_recruiting_soluble_αβ-tubulin_via_their_conserved_TOG_domains_to_polymerizing_microtubule_plus_ends.

description:
  XMAP215/Dis1 proteins, such as Alp14 and XMAP215, increase microtubules dynamic polymerization rates by recruiting soluble αβ-tubulin via their conserved TOG domains to polymerizing microtubule plus ends.


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01355
description: Clathrin-adaptor complex-3 beta-1 subunit C-terminal
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01355
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01355_Clathrin-adaptor_complex-3_beta-1_subunit_C-terminal


id: SM01368
description: Retinoblastoma-associated protein A domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01368
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01368_Retinoblastoma-associated_protein_A_domain


id: SM01371
description: Transcription factor IIA, alpha/beta subunit
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01371
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01371_Transcription_factor_IIA,_alpha/beta_subunit


id: SM01372
description: E2F/DP family winged-helix DNA-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01372
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01372_E2F/DP_family_winged-helix_DNA-binding_domain


id: SM01376
description: Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01376
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01376_Eukaryotic_elongation_factor_5A_hypusine,_DNA-binding_OB_fold


id: SM01377
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01377
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01377_Bovine_L40_has_been_identified_as_a_secondary_RNA_binding_protein_(PMID:3129699)._L40_is_fused_to_a_ubiquitin_protein_(PMID:7488009).

description:
  Bovine L40 has been identified as a secondary RNA binding protein (PMID:3129699). L40 is fused to a ubiquitin protein (PMID:7488009).


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01385
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01385
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01385_This_family_contains_the_breast_cancer_tumour_suppressor_BRCA2-interacting_protein_DSS1_and_its_homologue_SEM1,_both_of_which_are_short_acidic_proteins._DSS1_has_been_shown_to_be_a_conserved_component_of_the_Rae1_mediated_mRNA_export_pathway_in_...

description:
  This family contains the breast cancer tumour suppressor BRCA2-interacting protein DSS1 and its homologue SEM1, both of which are short acidic proteins. DSS1 has been shown to be a conserved component of the Rae1 mediated mRNA export pathway in ...


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01393
description: This family includes ribosomal protein L32 from eukaryotes and archaebacteria.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01393
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01393_This_family_includes_ribosomal_protein_L32_from_eukaryotes_and_archaebacteria.


id: SM01395
description: Transcription factor TFIIH complex subunit Tfb5
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01395
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01395_Transcription_factor_TFIIH_complex_subunit_Tfb5


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01406
description: Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01406
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01406_Family_of_proteins_with_a_conserved_region_found_in_PAPA-1,_a_PAP-1_binding_protein.


id: SM01408
description: Inhibitor of growth proteins N-terminal histone-binding
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01408
name:
  Protein Domains (SMART).STRING_v12.0_112509_STRINGid_SM01408_Inhibitor_of_growth_proteins_N-terminal_histone-binding


