# geneInfo

ensembl_gene_id: A0A2J6QR81
symbol: A0A2J6QR81
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: A0A2J6QRA9
symbol: A0A2J6QRA9
gene_biotype: protein_coding
description:
  FAD-binding domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.


ensembl_gene_id: A0A2J6QRD9
symbol: A0A2J6QRD9
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.


ensembl_gene_id: A0A2J6QRG4
symbol: A0A2J6QRG4
gene_biotype: protein_coding
description:
  Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A2J6QRL4
symbol: A0A2J6QRL4
gene_biotype: protein_coding
description:
  General substrate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QRL9
symbol: A0A2J6QRL9
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6QRX1
symbol: A0A2J6QRX1
gene_biotype: protein_coding
description:
  GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.


ensembl_gene_id: A0A2J6QS35
symbol: A0A2J6QS35
gene_biotype: protein_coding
description:
  MFS sugar transporter-like protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QSG2
symbol: A0A2J6QSG2
gene_biotype: protein_coding
description:
  Sugar transporter family protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QSH6
symbol: A0A2J6QSH6
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (fumarate); Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: A0A2J6QSM9
symbol: A0A2J6QSM9
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


ensembl_gene_id: A0A2J6QSN4
symbol: MED5
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 5; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6QSN9
symbol: MED19
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6QSR0
symbol: A0A2J6QSR0
gene_biotype: protein_coding
description:
  Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A2J6QSV7
symbol: A0A2J6QSV7
gene_biotype: protein_coding
description:
  P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the helicase family. Dicer subfamily.


ensembl_gene_id: A0A2J6QT21
symbol: A0A2J6QT21
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-epimerase; Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).


ensembl_gene_id: A0A2J6QT49
symbol: MED8
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6QTW0
symbol: A0A2J6QTW0
gene_biotype: protein_coding
description:
  P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A2J6QU85
symbol: UNG1
gene_biotype: protein_coding
description:
  Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: A0A2J6QUD5
symbol: ALG13
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.


ensembl_gene_id: A0A2J6QUM9
symbol: A0A2J6QUM9
gene_biotype: protein_coding
description:
  Cyanuric acid amidohydrolase; Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6- trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret; Belongs to the cyclic amide hydrolase (CyAH) family.


ensembl_gene_id: A0A2J6QUP2
symbol: A0A2J6QUP2
gene_biotype: protein_coding
description:
  MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QUU7
symbol: A0A2J6QUU7
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: A0A2J6QUV6
symbol: A0A2J6QUV6
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: A0A2J6QV32
symbol: A0A2J6QV32
gene_biotype: protein_coding
description:
  Putative hexose carrier protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QV40
symbol: A0A2J6QV40
gene_biotype: protein_coding
description:
  Putative hydroxyisocaproate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A2J6QVB0
symbol: PSD2
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily.


ensembl_gene_id: A0A2J6QVB7
symbol: A0A2J6QVB7
gene_biotype: protein_coding
description:
  Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.


ensembl_gene_id: A0A2J6QVI9
symbol: A0A2J6QVI9
gene_biotype: protein_coding
description:
  Putative polyol transporter 5; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QVN0
symbol: A0A2J6QVN0
gene_biotype: protein_coding
description:
  Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.


ensembl_gene_id: A0A2J6QVN7
symbol: A0A2J6QVN7
gene_biotype: protein_coding
description:
  Sugar transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QW22
symbol: A0A2J6QW22
gene_biotype: protein_coding
description:
  Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A2J6QW50
symbol: A0A2J6QW50
gene_biotype: protein_coding
description:
  Sn-1,2-diacylglycerol cholinephosphotransferas-like protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A2J6QWB4
symbol: A0A2J6QWB4
gene_biotype: protein_coding
description:
  NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.


ensembl_gene_id: A0A2J6QWI8
symbol: A0A2J6QWI8
gene_biotype: protein_coding
description:
  tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]


ensembl_gene_id: A0A2J6QWJ5
symbol: A0A2J6QWJ5
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.


ensembl_gene_id: A0A2J6QWQ1
symbol: A0A2J6QWQ1
gene_biotype: protein_coding
description:
  Putative short-chain oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6QWQ4
symbol: A0A2J6QWQ4
gene_biotype: protein_coding
description:
  NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.


ensembl_gene_id: A0A2J6QWS8
symbol: A0A2J6QWS8
gene_biotype: protein_coding
description:
  High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.


ensembl_gene_id: A0A2J6QWT4
symbol: A0A2J6QWT4
gene_biotype: protein_coding
description:
  Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A2J6QWT5
symbol: A0A2J6QWT5
gene_biotype: protein_coding
description:
  Sterol 24-C-methyltransferase; Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.


ensembl_gene_id: A0A2J6QWV0
symbol: MED17
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6QWV6
symbol: A0A2J6QWV6
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]


ensembl_gene_id: A0A2J6QWV9
symbol: A0A2J6QWV9
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily.


ensembl_gene_id: A0A2J6QWW4
symbol: A0A2J6QWW4
gene_biotype: protein_coding
description:
  ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.


ensembl_gene_id: A0A2J6QWX4
symbol: A0A2J6QWX4
gene_biotype: protein_coding
description:
  IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.


ensembl_gene_id: A0A2J6QWY2
symbol: A0A2J6QWY2
gene_biotype: protein_coding
description:
  V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A2J6QWY4
symbol: A0A2J6QWY4
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: A0A2J6QX26
symbol: A0A2J6QX26
gene_biotype: protein_coding
description:
  Mitochondrial GTPase 1; Mitochondrial GTPase involved in assembly of the large ribosomal subunit. Plays a role in expression of the mitochondrial translational machinery; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: A0A2J6QX28
symbol: A0A2J6QX28
gene_biotype: protein_coding
description:
  Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: A0A2J6QX35
symbol: A0A2J6QX35
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: A0A2J6QX95
symbol: A0A2J6QX95
gene_biotype: protein_coding
description:
  Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.


ensembl_gene_id: A0A2J6QXA0
symbol: A0A2J6QXA0
gene_biotype: protein_coding
description:
  Bifunctional cytochrome P450/NADPH--P450 reductase; In the N-terminal section; belongs to the cytochrome P450 family.


ensembl_gene_id: A0A2J6QXA2
symbol: A0A2J6QXA2
gene_biotype: protein_coding
description:
  Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.


ensembl_gene_id: A0A2J6QXD9
symbol: A0A2J6QXD9
gene_biotype: protein_coding
description:
  MFS quinate transporter-like protein QutD; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6QXE2
symbol: A0A2J6QXE2
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.


ensembl_gene_id: A0A2J6QXT3
symbol: A0A2J6QXT3
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 27; Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.


ensembl_gene_id: A0A2J6QXZ9
symbol: TRM82
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.


ensembl_gene_id: A0A2J6QY04
symbol: A0A2J6QY04
gene_biotype: protein_coding
description:
  60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10.


ensembl_gene_id: A0A2J6QY20
symbol: A0A2J6QY20
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]


ensembl_gene_id: A0A2J6QY36
symbol: A0A2J6QY36
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase-like protein 49 kDa subunit; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: A0A2J6QY42
symbol: A0A2J6QY42
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.


ensembl_gene_id: A0A2J6QY46
symbol: COQ6
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.


ensembl_gene_id: A0A2J6QY47
symbol: VMA21
gene_biotype: protein_coding
description:
  Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family.


ensembl_gene_id: A0A2J6QY50
symbol: A0A2J6QY50
gene_biotype: protein_coding
description:
  COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family.


ensembl_gene_id: A0A2J6QY59
symbol: A0A2J6QY59
gene_biotype: protein_coding
description:
  F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.


ensembl_gene_id: A0A2J6QY63
symbol: A0A2J6QY63
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]


ensembl_gene_id: A0A2J6QY67
symbol: A0A2J6QY67
gene_biotype: protein_coding
description:
  Mitochondrial phosphate carrier protein-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6QY76
symbol: A0A2J6QY76
gene_biotype: protein_coding
description:
  Autophagy-related protein; Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation; Belongs to the ATG22 family.


ensembl_gene_id: A0A2J6QY77
symbol: A0A2J6QY77
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6QY80
symbol: A0A2J6QY80
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: A0A2J6QY98
symbol: A0A2J6QY98
gene_biotype: protein_coding
description:
  MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A2J6QYE5
symbol: A0A2J6QYE5
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.


ensembl_gene_id: A0A2J6QYH6
symbol: A0A2J6QYH6
gene_biotype: protein_coding
description:
  Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]


ensembl_gene_id: A0A2J6QYL5
symbol: A0A2J6QYL5
gene_biotype: protein_coding
description:
  DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.


ensembl_gene_id: A0A2J6QYS2
symbol: NOP7
gene_biotype: protein_coding
description:
  Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.


ensembl_gene_id: A0A2J6QYU4
symbol: A0A2J6QYU4
gene_biotype: protein_coding
description:
  Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.


ensembl_gene_id: A0A2J6QYX1
symbol: A0A2J6QYX1
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).


ensembl_gene_id: A0A2J6QYX5
symbol: A0A2J6QYX5
gene_biotype: protein_coding
description:
  P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6QZ05
symbol: BNA4
gene_biotype: protein_coding
description:
  Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.


ensembl_gene_id: A0A2J6QZ08
symbol: A0A2J6QZ08
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A2J6QZ80
symbol: A0A2J6QZ80
gene_biotype: protein_coding
description:
  Putative glutamyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A2J6QZJ7
symbol: A0A2J6QZJ7
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A2J6QZK1
symbol: A0A2J6QZK1
gene_biotype: protein_coding
description:
  Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A2J6QZL9
symbol: A0A2J6QZL9
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6QZQ6
symbol: A0A2J6QZQ6
gene_biotype: protein_coding
description:
  Cysteine proteinase 1, mitochondrial; Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.


ensembl_gene_id: A0A2J6QZW6
symbol: A0A2J6QZW6
gene_biotype: protein_coding
description:
  Putative 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6QZW7
symbol: A0A2J6QZW7
gene_biotype: protein_coding
description:
  Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A2J6QZX9
symbol: A0A2J6QZX9
gene_biotype: protein_coding
description:
  Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.


ensembl_gene_id: A0A2J6R095
symbol: A0A2J6R095
gene_biotype: protein_coding
description:
  Fructose transporter 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R0E8
symbol: A0A2J6R0E8
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: A0A2J6R0J9
symbol: A0A2J6R0J9
gene_biotype: protein_coding
description:
  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Belongs to the metallo-dependent hydrolases superfamily.


ensembl_gene_id: A0A2J6R0K0
symbol: A0A2J6R0K0
gene_biotype: protein_coding
description:
  Putative maltose permease; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R0K6
symbol: A0A2J6R0K6
gene_biotype: protein_coding
description:
  Putative MFS monosaccharide transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R0M2
symbol: A0A2J6R0M2
gene_biotype: protein_coding
description:
  Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.


ensembl_gene_id: A0A2J6R0T2
symbol: A0A2J6R0T2
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: A0A2J6R101
symbol: A0A2J6R101
gene_biotype: protein_coding
description:
  Putative MFS maltose permease; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R131
symbol: A0A2J6R131
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6R140
symbol: A0A2J6R140
gene_biotype: protein_coding
description:
  Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: A0A2J6R1I6
symbol: A0A2J6R1I6
gene_biotype: protein_coding
description:
  1,3-beta-glucanosyltransferase; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall; Belongs to the glycosyl hydrolase 72 family.


ensembl_gene_id: A0A2J6R1K3
symbol: A0A2J6R1K3
gene_biotype: protein_coding
description:
  Putative sugar transporter STL1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R1Z4
symbol: A0A2J6R1Z4
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A2J6R1Z9
symbol: A0A2J6R1Z9
gene_biotype: protein_coding
description:
  P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A2J6R227
symbol: A0A2J6R227
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6R241
symbol: A0A2J6R241
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: A0A2J6R244
symbol: A0A2J6R244
gene_biotype: protein_coding
description:
  Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily.


ensembl_gene_id: A0A2J6R255
symbol: A0A2J6R255
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: A0A2J6R269
symbol: A0A2J6R269
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]


ensembl_gene_id: A0A2J6R280
symbol: A0A2J6R280
gene_biotype: protein_coding
description:
  Arginine N-methyltransferase 2; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.


ensembl_gene_id: A0A2J6R2E0
symbol: A0A2J6R2E0
gene_biotype: protein_coding
description:
  tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.


ensembl_gene_id: A0A2J6R2J4
symbol: A0A2J6R2J4
gene_biotype: protein_coding
description:
  Calcium-transporting ATPase type 2C member 1; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A2J6R2L0
symbol: A0A2J6R2L0
gene_biotype: protein_coding
description:
  Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.


ensembl_gene_id: A0A2J6R2R3
symbol: A0A2J6R2R3
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.


ensembl_gene_id: A0A2J6R2W3
symbol: A0A2J6R2W3
gene_biotype: protein_coding
description:
  Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.


ensembl_gene_id: A0A2J6R2Y9
symbol: A0A2J6R2Y9
gene_biotype: protein_coding
description:
  Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: A0A2J6R302
symbol: A0A2J6R302
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A2J6R3Y7
symbol: A0A2J6R3Y7
gene_biotype: protein_coding
description:
  Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.


ensembl_gene_id: A0A2J6R424
symbol: NBP35
gene_biotype: protein_coding
description:
  Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.


ensembl_gene_id: A0A2J6R4Q4
symbol: PAN3
gene_biotype: protein_coding
description:
  PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]


ensembl_gene_id: A0A2J6R4Q7
symbol: A0A2J6R4Q7
gene_biotype: protein_coding
description:
  Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: A0A2J6R4S5
symbol: A0A2J6R4S5
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: A0A2J6R4Z7
symbol: A0A2J6R4Z7
gene_biotype: protein_coding
description:
  Putative glutathione-dependent formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family.


ensembl_gene_id: A0A2J6R564
symbol: A0A2J6R564
gene_biotype: protein_coding
description:
  26S proteasome regulatory subunit RPN2; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.


ensembl_gene_id: A0A2J6R591
symbol: MEF1
gene_biotype: protein_coding
description:
  Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.


ensembl_gene_id: A0A2J6R5B1
symbol: A0A2J6R5B1
gene_biotype: protein_coding
description:
  Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.


ensembl_gene_id: A0A2J6R5B3
symbol: A0A2J6R5B3
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity.


ensembl_gene_id: A0A2J6R5D9
symbol: A0A2J6R5D9
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family.


ensembl_gene_id: A0A2J6R5F8
symbol: A0A2J6R5F8
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]


ensembl_gene_id: A0A2J6R5L1
symbol: A0A2J6R5L1
gene_biotype: protein_coding
description:
  Putative quinate permease; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R5M2
symbol: A0A2J6R5M2
gene_biotype: protein_coding
description:
  2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily.


ensembl_gene_id: A0A2J6R5R2
symbol: A0A2J6R5R2
gene_biotype: protein_coding
description:
  Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.


ensembl_gene_id: A0A2J6R604
symbol: A0A2J6R604
gene_biotype: protein_coding
description:
  Putative lactose permease; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R626
symbol: A0A2J6R626
gene_biotype: protein_coding
description:
  Kinesin-domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A2J6R662
symbol: A0A2J6R662
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: A0A2J6R669
symbol: CLU1
gene_biotype: protein_coding
description:
  Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.


ensembl_gene_id: A0A2J6R678
symbol: MED10
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6R684
symbol: A0A2J6R684
gene_biotype: protein_coding
description:
  Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.


ensembl_gene_id: A0A2J6R6A1
symbol: A0A2J6R6A1
gene_biotype: protein_coding
description:
  PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A2J6R6D2
symbol: A0A2J6R6D2
gene_biotype: protein_coding
description:
  Putative 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Belongs to the metallo-dependent hydrolases superfamily.


ensembl_gene_id: A0A2J6R6L2
symbol: TIF32
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6R6Z7
symbol: MED11
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6R724
symbol: A0A2J6R724
gene_biotype: protein_coding
description:
  Voltage-gated potassium channel; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A2J6R793
symbol: A0A2J6R793
gene_biotype: protein_coding
description:
  Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A2J6R798
symbol: A0A2J6R798
gene_biotype: protein_coding
description:
  FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]


ensembl_gene_id: A0A2J6R7D9
symbol: A0A2J6R7D9
gene_biotype: protein_coding
description:
  Dynamin family protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6R7E3
symbol: A0A2J6R7E3
gene_biotype: protein_coding
description:
  DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.


ensembl_gene_id: A0A2J6R7U3
symbol: YTM1
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.


ensembl_gene_id: A0A2J6R7V1
symbol: A0A2J6R7V1
gene_biotype: protein_coding
description:
  Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family.


ensembl_gene_id: A0A2J6R7X4
symbol: A0A2J6R7X4
gene_biotype: protein_coding
description:
  AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.


ensembl_gene_id: A0A2J6R7Z5
symbol: A0A2J6R7Z5
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A2J6R808
symbol: A0A2J6R808
gene_biotype: protein_coding
description:
  Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.


ensembl_gene_id: A0A2J6R858
symbol: LSM5
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.


ensembl_gene_id: A0A2J6R867
symbol: A0A2J6R867
gene_biotype: protein_coding
description:
  CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.


ensembl_gene_id: A0A2J6R869
symbol: A0A2J6R869
gene_biotype: protein_coding
description:
  Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.


ensembl_gene_id: A0A2J6R873
symbol: A0A2J6R873
gene_biotype: protein_coding
description:
  CDP-diacylglycerol-inositol 3-phosphatidyltransferas-like protein PIS; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A2J6R8B7
symbol: A0A2J6R8B7
gene_biotype: protein_coding
description:
  MFS quinate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R8C4
symbol: A0A2J6R8C4
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family.


ensembl_gene_id: A0A2J6R8E1
symbol: BNA5
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.


ensembl_gene_id: A0A2J6R8G2
symbol: A0A2J6R8G2
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores; Belongs to the V-ATPase V0D/AC39 subunit family.


ensembl_gene_id: A0A2J6R8G5
symbol: RPS0
gene_biotype: protein_coding
description:
  40S ribosomal protein S0; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.


ensembl_gene_id: A0A2J6R8J5
symbol: A0A2J6R8J5
gene_biotype: protein_coding
description:
  MFS maltose permease; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R8M6
symbol: A0A2J6R8M6
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.


ensembl_gene_id: A0A2J6R8Q1
symbol: A0A2J6R8Q1
gene_biotype: protein_coding
description:
  Putative sugar transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R8S0
symbol: A0A2J6R8S0
gene_biotype: protein_coding
description:
  AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.


ensembl_gene_id: A0A2J6R8T3
symbol: A0A2J6R8T3
gene_biotype: protein_coding
description:
  Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.


ensembl_gene_id: A0A2J6R8W8
symbol: A0A2J6R8W8
gene_biotype: protein_coding
description:
  Hexose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6R8Y5
symbol: A0A2J6R8Y5
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.


ensembl_gene_id: A0A2J6R8Z1
symbol: A0A2J6R8Z1
gene_biotype: protein_coding
description:
  37S ribosomal protein mrp10, mitochondrial; Involved in mitochondrial genome encoded proteins translation.


ensembl_gene_id: A0A2J6R901
symbol: A0A2J6R901
gene_biotype: protein_coding
description:
  7-alpha-hydroxysteroid dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6R941
symbol: PAC1
gene_biotype: protein_coding
description:
  Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.


ensembl_gene_id: A0A2J6R948
symbol: A0A2J6R948
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: A0A2J6R9F9
symbol: A0A2J6R9F9
gene_biotype: protein_coding
description:
  NADP-dependent dehydrogenase-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6R9J5
symbol: A0A2J6R9J5
gene_biotype: protein_coding
description:
  Nucleic acid-binding protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.


ensembl_gene_id: A0A2J6R9L2
symbol: A0A2J6R9L2
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.


ensembl_gene_id: A0A2J6R9L3
symbol: A0A2J6R9L3
gene_biotype: protein_coding
description:
  Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.


ensembl_gene_id: A0A2J6R9M6
symbol: A0A2J6R9M6
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily.


ensembl_gene_id: A0A2J6R9N8
symbol: A0A2J6R9N8
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: A0A2J6R9P2
symbol: A0A2J6R9P2
gene_biotype: protein_coding
description:
  Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.


ensembl_gene_id: A0A2J6R9P3
symbol: A0A2J6R9P3
gene_biotype: protein_coding
description:
  Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]


ensembl_gene_id: A0A2J6R9Q4
symbol: A0A2J6R9Q4
gene_biotype: protein_coding
description:
  S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.


ensembl_gene_id: A0A2J6R9S7
symbol: COQ5
gene_biotype: protein_coding
description:
  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: A0A2J6R9T5
symbol: A0A2J6R9T5
gene_biotype: protein_coding
description:
  Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.


ensembl_gene_id: A0A2J6R9U2
symbol: A0A2J6R9U2
gene_biotype: protein_coding
description:
  Nicotinamide-nucleotide adenylyltransferase; Belongs to the eukaryotic NMN adenylyltransferase family.


ensembl_gene_id: A0A2J6R9V9
symbol: A0A2J6R9V9
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase 30.4 kDa subunit mitochondrial; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: A0A2J6RA20
symbol: A0A2J6RA20
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6RA23
symbol: A0A2J6RA23
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.


ensembl_gene_id: A0A2J6RA37
symbol: A0A2J6RA37
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.


ensembl_gene_id: A0A2J6RA74
symbol: A0A2J6RA74
gene_biotype: protein_coding
description:
  Bifunctional acetylglutamate kinase/N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family.


ensembl_gene_id: A0A2J6RA80
symbol: A0A2J6RA80
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family.


ensembl_gene_id: A0A2J6RA93
symbol: A0A2J6RA93
gene_biotype: protein_coding
description:
  ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]


ensembl_gene_id: A0A2J6RAB9
symbol: A0A2J6RAB9
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: A0A2J6RAC7
symbol: A0A2J6RAC7
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A2J6RAD3
symbol: A0A2J6RAD3
gene_biotype: protein_coding
description:
  Calcium dependent mitochondrial carrier protein-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RAD6
symbol: A0A2J6RAD6
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A2J6RAE4
symbol: A0A2J6RAE4
gene_biotype: protein_coding
description:
  S-adenosylmethionine mitochondrial carrier protein-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RAF0
symbol: A0A2J6RAF0
gene_biotype: protein_coding
description:
  Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.


ensembl_gene_id: A0A2J6RAF1
symbol: A0A2J6RAF1
gene_biotype: protein_coding
description:
  Putative ribosomal protein arginine N-methytransferase rmt3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A2J6RAF9
symbol: A0A2J6RAF9
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family.  In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family.


ensembl_gene_id: A0A2J6RAH7
symbol: A0A2J6RAH7
gene_biotype: protein_coding
description:
  Magnesium-translocating P-type ATPase family protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A2J6RAI1
symbol: A0A2J6RAI1
gene_biotype: protein_coding
description:
  Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.


ensembl_gene_id: A0A2J6RAI5
symbol: A0A2J6RAI5
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


ensembl_gene_id: A0A2J6RAK3
symbol: A0A2J6RAK3
gene_biotype: protein_coding
description:
  tRNA wybutosine-synthesizing protein 2; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to the C-7 position of 4-demethylwyosine (imG-14) to produce wybutosine-86.


ensembl_gene_id: A0A2J6RAK8
symbol: A0A2J6RAK8
gene_biotype: protein_coding
description:
  Putative chromosome-associated kinesin KIF4B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A2J6RAQ7
symbol: A0A2J6RAQ7
gene_biotype: protein_coding
description:
  Thiolase-like protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.


ensembl_gene_id: A0A2J6RAR1
symbol: A0A2J6RAR1
gene_biotype: protein_coding
description:
  Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.


ensembl_gene_id: A0A2J6RAS7
symbol: A0A2J6RAS7
gene_biotype: protein_coding
description:
  F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.


ensembl_gene_id: A0A2J6RAT9
symbol: A0A2J6RAT9
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate.


ensembl_gene_id: A0A2J6RAU8
symbol: A0A2J6RAU8
gene_biotype: protein_coding
description:
  Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.


ensembl_gene_id: A0A2J6RAW3
symbol: A0A2J6RAW3
gene_biotype: protein_coding
description:
  GED domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6RAX9
symbol: A0A2J6RAX9
gene_biotype: protein_coding
description:
  Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.


ensembl_gene_id: A0A2J6RB22
symbol: A0A2J6RB22
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: A0A2J6RB30
symbol: A0A2J6RB30
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A2J6RBA2
symbol: A0A2J6RBA2
gene_biotype: protein_coding
description:
  Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.


ensembl_gene_id: A0A2J6RBD9
symbol: A0A2J6RBD9
gene_biotype: protein_coding
description:
  Sensitive to high expression protein 9, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology.


ensembl_gene_id: A0A2J6RBE5
symbol: A0A2J6RBE5
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: A0A2J6RBG6
symbol: A0A2J6RBG6
gene_biotype: protein_coding
description:
  Protein BCP1; Involved in nuclear export, actin cytoskeleton organization and vesicular transport; Belongs to the BCP1 family.


ensembl_gene_id: A0A2J6RBH0
symbol: A0A2J6RBH0
gene_biotype: protein_coding
description:
  Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.


ensembl_gene_id: A0A2J6RBH4
symbol: A0A2J6RBH4
gene_biotype: protein_coding
description:
  Family 2 glycosyltransferase; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A2J6RBI1
symbol: A0A2J6RBI1
gene_biotype: protein_coding
description:
  Translation initiation factor-like protein eif-2b subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: A0A2J6RBK2
symbol: A0A2J6RBK2
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6RBK7
symbol: A0A2J6RBK7
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.


ensembl_gene_id: A0A2J6RBQ6
symbol: A0A2J6RBQ6
gene_biotype: protein_coding
description:
  60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.


ensembl_gene_id: A0A2J6RBV3
symbol: CLP1
gene_biotype: protein_coding
description:
  mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.


ensembl_gene_id: A0A2J6RBX1
symbol: LIA1
gene_biotype: protein_coding
description:
  Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.


ensembl_gene_id: A0A2J6RBZ3
symbol: A0A2J6RBZ3
gene_biotype: protein_coding
description:
  Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.


ensembl_gene_id: A0A2J6RBZ7
symbol: A0A2J6RBZ7
gene_biotype: protein_coding
description:
  Protein transport protein BOS1; SNARE required for protein transport between the ER and the Golgi complex.


ensembl_gene_id: A0A2J6RC17
symbol: A0A2J6RC17
gene_biotype: protein_coding
description:
  AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.


ensembl_gene_id: A0A2J6RC39
symbol: A0A2J6RC39
gene_biotype: protein_coding
description:
  Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.


ensembl_gene_id: A0A2J6RC46
symbol: A0A2J6RC46
gene_biotype: protein_coding
description:
  GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.


ensembl_gene_id: A0A2J6RC57
symbol: A0A2J6RC57
gene_biotype: protein_coding
description:
  Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.


ensembl_gene_id: A0A2J6RC91
symbol: A0A2J6RC91
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...]


ensembl_gene_id: A0A2J6RCD1
symbol: A0A2J6RCD1
gene_biotype: protein_coding
description:
  Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-.


ensembl_gene_id: A0A2J6RCD7
symbol: A0A2J6RCD7
gene_biotype: protein_coding
description:
  26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.


ensembl_gene_id: A0A2J6RCE2
symbol: cprA
gene_biotype: protein_coding
description:
  NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: A0A2J6RCI1
symbol: A0A2J6RCI1
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.


ensembl_gene_id: A0A2J6RCS6
symbol: A0A2J6RCS6
gene_biotype: protein_coding
description:
  Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: A0A2J6RCV9
symbol: A0A2J6RCV9
gene_biotype: protein_coding
description:
  Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.


ensembl_gene_id: A0A2J6RD21
symbol: A0A2J6RD21
gene_biotype: protein_coding
description:
  Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.


ensembl_gene_id: A0A2J6RD43
symbol: A0A2J6RD43
gene_biotype: protein_coding
description:
  Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.


ensembl_gene_id: A0A2J6RD93
symbol: A0A2J6RD93
gene_biotype: protein_coding
description:
  DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.


ensembl_gene_id: A0A2J6RD97
symbol: A0A2J6RD97
gene_biotype: protein_coding
description:
  Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.


ensembl_gene_id: A0A2J6RDC4
symbol: A0A2J6RDC4
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A2J6RDN1
symbol: PSD1
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.


ensembl_gene_id: A0A2J6RDN8
symbol: EFM4
gene_biotype: protein_coding
description:
  Protein-lysine N-methyltransferase EFM4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.


ensembl_gene_id: A0A2J6RDP1
symbol: A0A2J6RDP1
gene_biotype: protein_coding
description:
  Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A2J6RDW9
symbol: A0A2J6RDW9
gene_biotype: protein_coding
description:
  Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.


ensembl_gene_id: A0A2J6RDX5
symbol: A0A2J6RDX5
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferas-like protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A2J6RDX6
symbol: A0A2J6RDX6
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.


ensembl_gene_id: A0A2J6RE25
symbol: A0A2J6RE25
gene_biotype: protein_coding
description:
  Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.


ensembl_gene_id: A0A2J6RED4
symbol: aguA
gene_biotype: protein_coding
description:
  Alpha-glucuronidase; Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases 4-O-methylglucuronic acid from xylan. Belongs to the glycosyl hydrolase 67 family.


ensembl_gene_id: A0A2J6REG8
symbol: TIF6
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family.


ensembl_gene_id: A0A2J6REH8
symbol: A0A2J6REH8
gene_biotype: protein_coding
description:
  Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.


ensembl_gene_id: A0A2J6REH9
symbol: A0A2J6REH9
gene_biotype: protein_coding
description:
  Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: A0A2J6REK5
symbol: A0A2J6REK5
gene_biotype: protein_coding
description:
  Protein PBN1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.


ensembl_gene_id: A0A2J6REK7
symbol: A0A2J6REK7
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: A0A2J6RER6
symbol: A0A2J6RER6
gene_biotype: protein_coding
description:
  5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A2J6RF38
symbol: SLX1
gene_biotype: protein_coding
description:
  Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.


ensembl_gene_id: A0A2J6RF94
symbol: A0A2J6RF94
gene_biotype: protein_coding
description:
  Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.


ensembl_gene_id: A0A2J6RFF1
symbol: A0A2J6RFF1
gene_biotype: protein_coding
description:
  NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: A0A2J6RFI0
symbol: A0A2J6RFI0
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.


ensembl_gene_id: A0A2J6RFI4
symbol: A0A2J6RFI4
gene_biotype: protein_coding
description:
  D-isomer-specific 2-hydroxyacid dehydrogenase-like protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A2J6RFK3
symbol: A0A2J6RFK3
gene_biotype: protein_coding
description:
  Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.


ensembl_gene_id: A0A2J6RFV2
symbol: A0A2J6RFV2
gene_biotype: protein_coding
description:
  20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family.


ensembl_gene_id: A0A2J6RG57
symbol: A0A2J6RG57
gene_biotype: protein_coding
description:
  NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450.


ensembl_gene_id: A0A2J6RG70
symbol: A0A2J6RG70
gene_biotype: protein_coding
description:
  Myo-inositol transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RG74
symbol: A0A2J6RG74
gene_biotype: protein_coding
description:
  FAD binding domain-containing protein; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.


ensembl_gene_id: A0A2J6RG89
symbol: A0A2J6RG89
gene_biotype: protein_coding
description:
  Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: A0A2J6RGB7
symbol: CFD1
gene_biotype: protein_coding
description:
  Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.


ensembl_gene_id: A0A2J6RGI2
symbol: A0A2J6RGI2
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: A0A2J6RGI8
symbol: A0A2J6RGI8
gene_biotype: protein_coding
description:
  Dynamin-1-like protein-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6RGV0
symbol: A0A2J6RGV0
gene_biotype: protein_coding
description:
  Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.


ensembl_gene_id: A0A2J6RGW4
symbol: A0A2J6RGW4
gene_biotype: protein_coding
description:
  Putative Na/K ATPase alpha 1 subunit; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A2J6RGW8
symbol: A0A2J6RGW8
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.


ensembl_gene_id: A0A2J6RH67
symbol: A0A2J6RH67
gene_biotype: protein_coding
description:
  GPI-anchored wall transfer protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.


ensembl_gene_id: A0A2J6RHK9
symbol: A0A2J6RHK9
gene_biotype: protein_coding
description:
  Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: A0A2J6RHR2
symbol: A0A2J6RHR2
gene_biotype: protein_coding
description:
  Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.


ensembl_gene_id: A0A2J6RHU2
symbol: A0A2J6RHU2
gene_biotype: protein_coding
description:
  U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA.


ensembl_gene_id: A0A2J6RHU5
symbol: USB1
gene_biotype: protein_coding
description:
  U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family.


ensembl_gene_id: A0A2J6RHY7
symbol: A0A2J6RHY7
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.


ensembl_gene_id: A0A2J6RHZ2
symbol: ADK2
gene_biotype: protein_coding
description:
  GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.


ensembl_gene_id: A0A2J6RI12
symbol: A0A2J6RI12
gene_biotype: protein_coding
description:
  Glucose transporter-like protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RI63
symbol: A0A2J6RI63
gene_biotype: protein_coding
description:
  Urease; In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.


ensembl_gene_id: A0A2J6RI64
symbol: A0A2J6RI64
gene_biotype: protein_coding
description:
  Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.


ensembl_gene_id: A0A2J6RI90
symbol: A0A2J6RI90
gene_biotype: protein_coding
description:
  Urea active transporter-like protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A2J6RIA0
symbol: A0A2J6RIA0
gene_biotype: protein_coding
description:
  Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.


ensembl_gene_id: A0A2J6RIB8
symbol: A0A2J6RIB8
gene_biotype: protein_coding
description:
  Putative myosin type I heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A2J6RIC3
symbol: A0A2J6RIC3
gene_biotype: protein_coding
description:
  Oxidoreductase,short chain dehydrogenase-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6RID9
symbol: PFA4
gene_biotype: protein_coding
description:
  Palmitoyltransferase PFA4; Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function; Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.


ensembl_gene_id: A0A2J6RIG2
symbol: ALA1
gene_biotype: protein_coding
description:
  Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A2J6RIH1
symbol: A0A2J6RIH1
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.


ensembl_gene_id: A0A2J6RIH5
symbol: NAT10
gene_biotype: protein_coding
description:
  RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.


ensembl_gene_id: A0A2J6RIN2
symbol: A0A2J6RIN2
gene_biotype: protein_coding
description:
  40S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.


ensembl_gene_id: A0A2J6RIN5
symbol: SLX4
gene_biotype: protein_coding
description:
  Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.


ensembl_gene_id: A0A2J6RIP2
symbol: A0A2J6RIP2
gene_biotype: protein_coding
description:
  NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: A0A2J6RIS2
symbol: MDM12
gene_biotype: protein_coding
description:
  Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...]


ensembl_gene_id: A0A2J6RIS3
symbol: A0A2J6RIS3
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.


ensembl_gene_id: A0A2J6RIT4
symbol: A0A2J6RIT4
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.


ensembl_gene_id: A0A2J6RJ15
symbol: A0A2J6RJ15
gene_biotype: protein_coding
description:
  tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.


ensembl_gene_id: A0A2J6RJ23
symbol: A0A2J6RJ23
gene_biotype: protein_coding
description:
  Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).


ensembl_gene_id: A0A2J6RJ96
symbol: A0A2J6RJ96
gene_biotype: protein_coding
description:
  Putative ABC transporter CDR4; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.


ensembl_gene_id: A0A2J6RJJ4
symbol: A0A2J6RJJ4
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.


ensembl_gene_id: A0A2J6RJR5
symbol: A0A2J6RJR5
gene_biotype: protein_coding
description:
  ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: A0A2J6RJS0
symbol: A0A2J6RJS0
gene_biotype: protein_coding
description:
  RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.


ensembl_gene_id: A0A2J6RJW6
symbol: A0A2J6RJW6
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase 78 kDa subunit mitochondrial; Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: A0A2J6RJX5
symbol: A0A2J6RJX5
gene_biotype: protein_coding
description:
  NOL1/NOP2/sun family putative RNA met; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A2J6RK29
symbol: A0A2J6RK29
gene_biotype: protein_coding
description:
  Putative mitochondrial DNA replication protein YHM2; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RK49
symbol: A0A2J6RK49
gene_biotype: protein_coding
description:
  Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: A0A2J6RKF6
symbol: A0A2J6RKF6
gene_biotype: protein_coding
description:
  RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A2J6RKH0
symbol: A0A2J6RKH0
gene_biotype: protein_coding
description:
  Dynamin protein-like protein dnm1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6RKH7
symbol: ADK1
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.


ensembl_gene_id: A0A2J6RKH8
symbol: A0A2J6RKH8
gene_biotype: protein_coding
description:
  Putative peroxisomal membrane protein PMP47A; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RKH9
symbol: A0A2J6RKH9
gene_biotype: protein_coding
description:
  Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.


ensembl_gene_id: A0A2J6RKI7
symbol: A0A2J6RKI7
gene_biotype: protein_coding
description:
  Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A2J6RKL5
symbol: SEY1
gene_biotype: protein_coding
description:
  Protein SEY1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily.


ensembl_gene_id: A0A2J6RKL7
symbol: TRM5
gene_biotype: protein_coding
description:
  tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.


ensembl_gene_id: A0A2J6RKQ0
symbol: A0A2J6RKQ0
gene_biotype: protein_coding
description:
  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase-like protein; Belongs to the metallo-dependent hydrolases superfamily.


ensembl_gene_id: A0A2J6RKV6
symbol: A0A2J6RKV6
gene_biotype: protein_coding
description:
  Mitochondrial oxaloacetate transport protein-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RKY0
symbol: SPB1
gene_biotype: protein_coding
description:
  AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.


ensembl_gene_id: A0A2J6RKY9
symbol: NCS2
gene_biotype: protein_coding
description:
  Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.


ensembl_gene_id: A0A2J6RKZ2
symbol: A0A2J6RKZ2
gene_biotype: protein_coding
description:
  Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.


ensembl_gene_id: A0A2J6RL19
symbol: cnxH
gene_biotype: protein_coding
description:
  Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.


ensembl_gene_id: A0A2J6RL30
symbol: A0A2J6RL30
gene_biotype: protein_coding
description:
  Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.


ensembl_gene_id: A0A2J6RL41
symbol: COQ4
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.


ensembl_gene_id: A0A2J6RL47
symbol: A0A2J6RL47
gene_biotype: protein_coding
description:
  MFS general substrate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RL81
symbol: A0A2J6RL81
gene_biotype: protein_coding
description:
  Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: A0A2J6RLF2
symbol: A0A2J6RLF2
gene_biotype: protein_coding
description:
  Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.


ensembl_gene_id: A0A2J6RLI5
symbol: A0A2J6RLI5
gene_biotype: protein_coding
description:
  Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.


ensembl_gene_id: A0A2J6RLM4
symbol: A0A2J6RLM4
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


ensembl_gene_id: A0A2J6RLS5
symbol: PRT1
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.


ensembl_gene_id: A0A2J6RLV3
symbol: A0A2J6RLV3
gene_biotype: protein_coding
description:
  Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A2J6RLV8
symbol: A0A2J6RLV8
gene_biotype: protein_coding
description:
  Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.


ensembl_gene_id: A0A2J6RLY3
symbol: uba4
gene_biotype: protein_coding
description:
  Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide  [...]


ensembl_gene_id: A0A2J6RM07
symbol: MCM7
gene_biotype: protein_coding
description:
  DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]


ensembl_gene_id: A0A2J6RM14
symbol: A0A2J6RM14
gene_biotype: protein_coding
description:
  Hexose transporter-like protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RM68
symbol: A0A2J6RM68
gene_biotype: protein_coding
description:
  Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.


ensembl_gene_id: A0A2J6RMH9
symbol: cnxG
gene_biotype: protein_coding
description:
  Molybdopterin synthase sulfur carrier subunit; Acts as a sulfur carrier required for molybdopterin biosynthesis. Component of the molybdopterin synthase complex that catalyzes the conversion of precursor Z into molybdopterin by mediating the incorporation of 2 sulfur atoms into precursor Z to generate a dithiolene group. In the complex, serves as sulfur donor by being thiocarboxylated (-COSH) at its C-terminus by UBA4. After interaction with MOCS2B, the sulfur is then transferred to precursor Z to form molybdopterin.


ensembl_gene_id: A0A2J6RML9
symbol: HCR1
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6RMP8
symbol: A0A2J6RMP8
gene_biotype: protein_coding
description:
  Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.


ensembl_gene_id: A0A2J6RMQ0
symbol: MDE1
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).


ensembl_gene_id: A0A2J6RMQ7
symbol: A0A2J6RMQ7
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A2J6RMQ8
symbol: MRI1
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.


ensembl_gene_id: A0A2J6RMR4
symbol: A0A2J6RMR4
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.


ensembl_gene_id: A0A2J6RMT5
symbol: A0A2J6RMT5
gene_biotype: protein_coding
description:
  Golgi apparatus membrane protein TVP23; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP23 family.


ensembl_gene_id: A0A2J6RMT8
symbol: A0A2J6RMT8
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6RMU3
symbol: A0A2J6RMU3
gene_biotype: protein_coding
description:
  Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: A0A2J6RMU8
symbol: A0A2J6RMU8
gene_biotype: protein_coding
description:
  Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.


ensembl_gene_id: A0A2J6RMV3
symbol: A0A2J6RMV3
gene_biotype: protein_coding
description:
  Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.


ensembl_gene_id: A0A2J6RMW4
symbol: A0A2J6RMW4
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: A0A2J6RMY0
symbol: A0A2J6RMY0
gene_biotype: protein_coding
description:
  GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.


ensembl_gene_id: A0A2J6RMZ1
symbol: BNA1
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.


ensembl_gene_id: A0A2J6RN43
symbol: A0A2J6RN43
gene_biotype: protein_coding
description:
  Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.


ensembl_gene_id: A0A2J6RNA5
symbol: A0A2J6RNA5
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.


ensembl_gene_id: A0A2J6RNA6
symbol: A0A2J6RNA6
gene_biotype: protein_coding
description:
  Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.


ensembl_gene_id: A0A2J6RNE5
symbol: A0A2J6RNE5
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: A0A2J6RNI0
symbol: hxB
gene_biotype: protein_coding
description:
  Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.


ensembl_gene_id: A0A2J6RNI9
symbol: A0A2J6RNI9
gene_biotype: protein_coding
description:
  Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A2J6RNL8
symbol: A0A2J6RNL8
gene_biotype: protein_coding
description:
  DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: A0A2J6RNM4
symbol: A0A2J6RNM4
gene_biotype: protein_coding
description:
  Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.


ensembl_gene_id: A0A2J6RNP7
symbol: A0A2J6RNP7
gene_biotype: protein_coding
description:
  U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.


ensembl_gene_id: A0A2J6RNQ8
symbol: A0A2J6RNQ8
gene_biotype: protein_coding
description:
  Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: A0A2J6RNR6
symbol: A0A2J6RNR6
gene_biotype: protein_coding
description:
  Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.


ensembl_gene_id: A0A2J6RNR7
symbol: A0A2J6RNR7
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.


ensembl_gene_id: A0A2J6RNV2
symbol: A0A2J6RNV2
gene_biotype: protein_coding
description:
  mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family.


ensembl_gene_id: A0A2J6RP11
symbol: A0A2J6RP11
gene_biotype: protein_coding
description:
  Putative Brefeldin A resistance protein; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.


ensembl_gene_id: A0A2J6RPF9
symbol: A0A2J6RPF9
gene_biotype: protein_coding
description:
  Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.


ensembl_gene_id: A0A2J6RPL6
symbol: A0A2J6RPL6
gene_biotype: protein_coding
description:
  Mitochondrial inner membrane protease ATP23; Has a dual role in the assembly of mitochondrial ATPase. Belongs to the peptidase M76 family.


ensembl_gene_id: A0A2J6RPR5
symbol: A0A2J6RPR5
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: A0A2J6RPT0
symbol: A0A2J6RPT0
gene_biotype: protein_coding
description:
  Putative Arginyl-tRNA synthetase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A2J6RQ34
symbol: A0A2J6RQ34
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: A0A2J6RQ52
symbol: A0A2J6RQ52
gene_biotype: protein_coding
description:
  Putative peroxisomal adenine nucleotide transporter 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RQ88
symbol: A0A2J6RQ88
gene_biotype: protein_coding
description:
  Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The  [...]


ensembl_gene_id: A0A2J6RQE9
symbol: A0A2J6RQE9
gene_biotype: protein_coding
description:
  Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family.


ensembl_gene_id: A0A2J6RQJ8
symbol: A0A2J6RQJ8
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: A0A2J6RQK4
symbol: A0A2J6RQK4
gene_biotype: protein_coding
description:
  Putative peroxisomal 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A2J6RQL8
symbol: A0A2J6RQL8
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.


ensembl_gene_id: A0A2J6RQQ9
symbol: A0A2J6RQQ9
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.


ensembl_gene_id: A0A2J6RQS8
symbol: MDM34
gene_biotype: protein_coding
description:
  Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.


ensembl_gene_id: A0A2J6RQU0
symbol: A0A2J6RQU0
gene_biotype: protein_coding
description:
  Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).


ensembl_gene_id: A0A2J6RR52
symbol: A0A2J6RR52
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: A0A2J6RR94
symbol: A0A2J6RR94
gene_biotype: protein_coding
description:
  Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.


ensembl_gene_id: A0A2J6RRA3
symbol: A0A2J6RRA3
gene_biotype: protein_coding
description:
  60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.


ensembl_gene_id: A0A2J6RRB1
symbol: A0A2J6RRB1
gene_biotype: protein_coding
description:
  Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.


ensembl_gene_id: A0A2J6RRM2
symbol: cyn1
gene_biotype: protein_coding
description:
  Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: A0A2J6RS07
symbol: A0A2J6RS07
gene_biotype: protein_coding
description:
  P-loop containing nucleoside triphosphate hydrolase protein; Belongs to the adenylate kinase family.


ensembl_gene_id: A0A2J6RS35
symbol: A0A2J6RS35
gene_biotype: protein_coding
description:
  2,3-dihydroxybenzoic acid decarboxylase dhbD; Belongs to the metallo-dependent hydrolases superfamily.


ensembl_gene_id: A0A2J6RS65
symbol: katG
gene_biotype: protein_coding
description:
  Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Confers resistance to H(2)O(2) in hyphae. May play an antioxidative role in fungal defense against the host-produced H(2)O(2) (oxidative burst) at the early stage of plant infection.


ensembl_gene_id: A0A2J6RS85
symbol: LSM3
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A2J6RS96
symbol: A0A2J6RS96
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.


ensembl_gene_id: A0A2J6RSB3
symbol: A0A2J6RSB3
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.


ensembl_gene_id: A0A2J6RSE9
symbol: A0A2J6RSE9
gene_biotype: protein_coding
description:
  Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily.


ensembl_gene_id: A0A2J6RSF9
symbol: A0A2J6RSF9
gene_biotype: protein_coding
description:
  Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.


ensembl_gene_id: A0A2J6RSG4
symbol: MDM10
gene_biotype: protein_coding
description:
  Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...]


ensembl_gene_id: A0A2J6RSG6
symbol: A0A2J6RSG6
gene_biotype: protein_coding
description:
  Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.


ensembl_gene_id: A0A2J6RSJ6
symbol: A0A2J6RSJ6
gene_biotype: protein_coding
description:
  Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.


ensembl_gene_id: A0A2J6RSJ8
symbol: COQ3
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: A0A2J6RSK2
symbol: A0A2J6RSK2
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.


ensembl_gene_id: A0A2J6RSL7
symbol: A0A2J6RSL7
gene_biotype: protein_coding
description:
  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors  [...]


ensembl_gene_id: A0A2J6RSN5
symbol: A0A2J6RSN5
gene_biotype: protein_coding
description:
  Sortilin; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.


ensembl_gene_id: A0A2J6RSP2
symbol: A0A2J6RSP2
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: A0A2J6RSP6
symbol: A0A2J6RSP6
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: A0A2J6RSQ1
symbol: A0A2J6RSQ1
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: A0A2J6RST1
symbol: A0A2J6RST1
gene_biotype: protein_coding
description:
  Acetoin dehydrogenase-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6RST8
symbol: A0A2J6RST8
gene_biotype: protein_coding
description:
  ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family.


ensembl_gene_id: A0A2J6RSU4
symbol: A0A2J6RSU4
gene_biotype: protein_coding
description:
  Mitochondrial thiamine pyrophosphate carrier 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RSY4
symbol: A0A2J6RSY4
gene_biotype: protein_coding
description:
  Putative short-chain type dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6RT04
symbol: A0A2J6RT04
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs.


ensembl_gene_id: A0A2J6RT14
symbol: A0A2J6RT14
gene_biotype: protein_coding
description:
  ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER). Belongs to the EMC3 family.


ensembl_gene_id: A0A2J6RT68
symbol: A0A2J6RT68
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A2J6RTE6
symbol: A0A2J6RTE6
gene_biotype: protein_coding
description:
  rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family.


ensembl_gene_id: A0A2J6RTJ5
symbol: A0A2J6RTJ5
gene_biotype: protein_coding
description:
  High-affinity glucose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RTL3
symbol: A0A2J6RTL3
gene_biotype: protein_coding
description:
  2OG-Fe(II) oxygenase superfamily protein; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: A0A2J6RTW5
symbol: A0A2J6RTW5
gene_biotype: protein_coding
description:
  Carbohydrate-binding module family 1 protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: A0A2J6RU02
symbol: A0A2J6RU02
gene_biotype: protein_coding
description:
  rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.


ensembl_gene_id: A0A2J6RU14
symbol: A0A2J6RU14
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: A0A2J6RU56
symbol: A0A2J6RU56
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenases/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6RU67
symbol: A0A2J6RU67
gene_biotype: protein_coding
description:
  T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.


ensembl_gene_id: A0A2J6RU80
symbol: A0A2J6RU80
gene_biotype: protein_coding
description:
  Cytochrome c oxidase assembly protein COX20, mitochondrial; Involved in the assembly of the cytochrome c oxidase complex. Belongs to the COX20 family.


ensembl_gene_id: A0A2J6RUA2
symbol: A0A2J6RUA2
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6RUB7
symbol: TSR3
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein TSR3; Ribosome biogenesis protein required for processing 35S pre- rRNA at site D; Belongs to the TSR3 family.


ensembl_gene_id: A0A2J6RUH6
symbol: A0A2J6RUH6
gene_biotype: protein_coding
description:
  Putative MFS sugar transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RUS9
symbol: A0A2J6RUS9
gene_biotype: protein_coding
description:
  Uncharacterized protein; Involved in DNA replication and cell separation. Belongs to the SDS23 family.


ensembl_gene_id: A0A2J6RUZ7
symbol: A0A2J6RUZ7
gene_biotype: protein_coding
description:
  Major facilitator superfamily transporter sugar; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RV00
symbol: A0A2J6RV00
gene_biotype: protein_coding
description:
  Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).


ensembl_gene_id: A0A2J6RV21
symbol: A0A2J6RV21
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.


ensembl_gene_id: A0A2J6RV65
symbol: EFM5
gene_biotype: protein_coding
description:
  Protein-lysine N-methyltransferase EFM5; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that trimethylates elongation factor 1-alpha at 'Lys- 79'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.


ensembl_gene_id: A0A2J6RV96
symbol: INT6
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6RVG7
symbol: A0A2J6RVG7
gene_biotype: protein_coding
description:
  DNA mismatch repair protein msh-2; Component of the post-replicative DNA mismatch repair system (MMR).


ensembl_gene_id: A0A2J6RVI7
symbol: A0A2J6RVI7
gene_biotype: protein_coding
description:
  Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.


ensembl_gene_id: A0A2J6RVJ3
symbol: MED9
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6RVK2
symbol: A0A2J6RVK2
gene_biotype: protein_coding
description:
  Mitochondrial tricarboxylate transporter-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RVM3
symbol: A0A2J6RVM3
gene_biotype: protein_coding
description:
  Jacalin-type lectin domain-containing protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A2J6RVM8
symbol: A0A2J6RVM8
gene_biotype: protein_coding
description:
  Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy.


ensembl_gene_id: A0A2J6RVN0
symbol: A0A2J6RVN0
gene_biotype: protein_coding
description:
  H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine (psi) residues may serve to stabilize the conformation of rRNAs.


ensembl_gene_id: A0A2J6RVN9
symbol: A0A2J6RVN9
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: A0A2J6RVP3
symbol: A0A2J6RVP3
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein; Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.


ensembl_gene_id: A0A2J6RVQ2
symbol: A0A2J6RVQ2
gene_biotype: protein_coding
description:
  DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.


ensembl_gene_id: A0A2J6RVQ7
symbol: A0A2J6RVQ7
gene_biotype: protein_coding
description:
  RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.


ensembl_gene_id: A0A2J6RVQ9
symbol: A0A2J6RVQ9
gene_biotype: protein_coding
description:
  Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.


ensembl_gene_id: A0A2J6RVR5
symbol: A0A2J6RVR5
gene_biotype: protein_coding
description:
  Mitochondrial RNA splicing protein-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6RVS5
symbol: A0A2J6RVS5
gene_biotype: protein_coding
description:
  Conserved oligomeric Golgi complex subunit 6; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.


ensembl_gene_id: A0A2J6RVS8
symbol: A0A2J6RVS8
gene_biotype: protein_coding
description:
  Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.


ensembl_gene_id: A0A2J6RVT7
symbol: A0A2J6RVT7
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6RVU7
symbol: A0A2J6RVU7
gene_biotype: protein_coding
description:
  Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.


ensembl_gene_id: A0A2J6RVW3
symbol: A0A2J6RVW3
gene_biotype: protein_coding
description:
  Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.


ensembl_gene_id: A0A2J6RW46
symbol: FEN1
gene_biotype: protein_coding
description:
  Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as  [...]


ensembl_gene_id: A0A2J6RWB9
symbol: A0A2J6RWB9
gene_biotype: protein_coding
description:
  Putative MFS alpha-glucoside transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RWI5
symbol: A0A2J6RWI5
gene_biotype: protein_coding
description:
  Putative glucose transporter rco-3; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RWM6
symbol: A0A2J6RWM6
gene_biotype: protein_coding
description:
  Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.


ensembl_gene_id: A0A2J6RWT1
symbol: A0A2J6RWT1
gene_biotype: protein_coding
description:
  Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.


ensembl_gene_id: A0A2J6RWV5
symbol: MED6
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6RX37
symbol: A0A2J6RX37
gene_biotype: protein_coding
description:
  Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: A0A2J6RXK1
symbol: A0A2J6RXK1
gene_biotype: protein_coding
description:
  Protein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family.


ensembl_gene_id: A0A2J6RXM3
symbol: URM1
gene_biotype: protein_coding
description:
  Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]


ensembl_gene_id: A0A2J6RXQ4
symbol: A0A2J6RXQ4
gene_biotype: protein_coding
description:
  Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family.


ensembl_gene_id: A0A2J6RXS1
symbol: A0A2J6RXS1
gene_biotype: protein_coding
description:
  Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.


ensembl_gene_id: A0A2J6RXT8
symbol: A0A2J6RXT8
gene_biotype: protein_coding
description:
  Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.


ensembl_gene_id: A0A2J6RXU0
symbol: NIP1
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6RXW1
symbol: A0A2J6RXW1
gene_biotype: protein_coding
description:
  Cardiolipin synthase-like protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A2J6RXX7
symbol: UTR4
gene_biotype: protein_coding
description:
  Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).


ensembl_gene_id: A0A2J6RXY2
symbol: A0A2J6RXY2
gene_biotype: protein_coding
description:
  25S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family.


ensembl_gene_id: A0A2J6RXZ0
symbol: A0A2J6RXZ0
gene_biotype: protein_coding
description:
  Ribosomal lysine N-methyltransferase 4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that monomethylates 60S ribosomal protein L42. Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.


ensembl_gene_id: A0A2J6RXZ1
symbol: KAE1
gene_biotype: protein_coding
description:
  tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...]


ensembl_gene_id: A0A2J6RY01
symbol: A0A2J6RY01
gene_biotype: protein_coding
description:
  Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: A0A2J6RY02
symbol: A0A2J6RY02
gene_biotype: protein_coding
description:
  DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.


ensembl_gene_id: A0A2J6RY07
symbol: A0A2J6RY07
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: A0A2J6RY10
symbol: A0A2J6RY10
gene_biotype: protein_coding
description:
  Class V myosin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A2J6RY20
symbol: A0A2J6RY20
gene_biotype: protein_coding
description:
  Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.


ensembl_gene_id: A0A2J6RY34
symbol: A0A2J6RY34
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.


ensembl_gene_id: A0A2J6RY77
symbol: A0A2J6RY77
gene_biotype: protein_coding
description:
  Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.


ensembl_gene_id: A0A2J6RYK2
symbol: A0A2J6RYK2
gene_biotype: protein_coding
description:
  Protein RER1; Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.


ensembl_gene_id: A0A2J6RYM4
symbol: A0A2J6RYM4
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6RYS6
symbol: A0A2J6RYS6
gene_biotype: protein_coding
description:
  Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family.


ensembl_gene_id: A0A2J6RYT9
symbol: A0A2J6RYT9
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.


ensembl_gene_id: A0A2J6RYU3
symbol: A0A2J6RYU3
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.


ensembl_gene_id: A0A2J6RYV0
symbol: A0A2J6RYV0
gene_biotype: protein_coding
description:
  Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.


ensembl_gene_id: A0A2J6RYZ2
symbol: A0A2J6RYZ2
gene_biotype: protein_coding
description:
  Putative MFS lactose permease; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6RZ04
symbol: ADI1
gene_biotype: protein_coding
description:
  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).


ensembl_gene_id: A0A2J6RZ19
symbol: MMM1
gene_biotype: protein_coding
description:
  Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...]


ensembl_gene_id: A0A2J6RZ53
symbol: A0A2J6RZ53
gene_biotype: protein_coding
description:
  Exocyst complex component SEC15; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.


ensembl_gene_id: A0A2J6RZ62
symbol: A0A2J6RZ62
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: A0A2J6RZK5
symbol: A0A2J6RZK5
gene_biotype: protein_coding
description:
  Tethering factor for nuclear proteasome sts1; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.


ensembl_gene_id: A0A2J6RZM2
symbol: A0A2J6RZM2
gene_biotype: protein_coding
description:
  Sphingolipid delta(4)-desaturase; Delta(4)-fatty-acid desaturase which introduces a double bond at the 4-position in the long-chain base (LCB) of ceramides.


ensembl_gene_id: A0A2J6RZQ0
symbol: A0A2J6RZQ0
gene_biotype: protein_coding
description:
  Mitochondrial ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: A0A2J6RZQ1
symbol: GET1
gene_biotype: protein_coding
description:
  Protein GET1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.


ensembl_gene_id: A0A2J6RZQ6
symbol: MED18
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6RZT1
symbol: ALG14
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine transferase subunit ALG14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.


ensembl_gene_id: A0A2J6RZY5
symbol: A0A2J6RZY5
gene_biotype: protein_coding
description:
  Cell division control protein 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A2J6RZZ9
symbol: A0A2J6RZZ9
gene_biotype: protein_coding
description:
  Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.


ensembl_gene_id: A0A2J6S026
symbol: A0A2J6S026
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family.


ensembl_gene_id: A0A2J6S048
symbol: GUF1
gene_biotype: protein_coding
description:
  Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.


ensembl_gene_id: A0A2J6S079
symbol: A0A2J6S079
gene_biotype: protein_coding
description:
  Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.


ensembl_gene_id: A0A2J6S095
symbol: TIF34
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6S098
symbol: A0A2J6S098
gene_biotype: protein_coding
description:
  Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.


ensembl_gene_id: A0A2J6S0B6
symbol: A0A2J6S0B6
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6S0C0
symbol: A0A2J6S0C0
gene_biotype: protein_coding
description:
  U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.


ensembl_gene_id: A0A2J6S0C9
symbol: A0A2J6S0C9
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A2J6S0D0
symbol: A0A2J6S0D0
gene_biotype: protein_coding
description:
  Mitochondrial NADH-ubiquinone oxidoreductase 20 kd subunit; Belongs to the complex I 20 kDa subunit family.


ensembl_gene_id: A0A2J6S0D5
symbol: EFM6
gene_biotype: protein_coding
description:
  Protein-lysine N-methyltransferase EFM6; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.


ensembl_gene_id: A0A2J6S0E3
symbol: A0A2J6S0E3
gene_biotype: protein_coding
description:
  U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family.


ensembl_gene_id: A0A2J6S0H9
symbol: A0A2J6S0H9
gene_biotype: protein_coding
description:
  Oligosaccharide translocation protein RFT1; May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane; Belongs to the RFT1 family.


ensembl_gene_id: A0A2J6S0I7
symbol: A0A2J6S0I7
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.


ensembl_gene_id: A0A2J6S0J6
symbol: DRE2
gene_biotype: protein_coding
description:
  Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by  [...]


ensembl_gene_id: A0A2J6S0K0
symbol: A0A2J6S0K0
gene_biotype: protein_coding
description:
  mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.


ensembl_gene_id: A0A2J6S0S4
symbol: COQ7
gene_biotype: protein_coding
description:
  5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.


ensembl_gene_id: A0A2J6S0U9
symbol: A0A2J6S0U9
gene_biotype: protein_coding
description:
  Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.


ensembl_gene_id: A0A2J6S0Z6
symbol: A0A2J6S0Z6
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: A0A2J6S103
symbol: A0A2J6S103
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: A0A2J6S1D3
symbol: A0A2J6S1D3
gene_biotype: protein_coding
description:
  Dynamin family protein-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6S1K9
symbol: A0A2J6S1K9
gene_biotype: protein_coding
description:
  Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]


ensembl_gene_id: A0A2J6S1L0
symbol: aguA-2
gene_biotype: protein_coding
description:
  Alpha-glucuronidase; Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases 4-O-methylglucuronic acid from xylan.


ensembl_gene_id: A0A2J6S1L4
symbol: A0A2J6S1L4
gene_biotype: protein_coding
description:
  Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.


ensembl_gene_id: A0A2J6S1L5
symbol: A0A2J6S1L5
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.


ensembl_gene_id: A0A2J6S1R1
symbol: A0A2J6S1R1
gene_biotype: protein_coding
description:
  General alpha-glucoside permease; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6S212
symbol: GET3
gene_biotype: protein_coding
description:
  ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]


ensembl_gene_id: A0A2J6S234
symbol: A0A2J6S234
gene_biotype: protein_coding
description:
  5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: A0A2J6S2I8
symbol: LSM1
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm1; Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.


ensembl_gene_id: A0A2J6S2K2
symbol: A0A2J6S2K2
gene_biotype: protein_coding
description:
  Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family.


ensembl_gene_id: A0A2J6S2M6
symbol: A0A2J6S2M6
gene_biotype: protein_coding
description:
  Mitochondrial cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.


ensembl_gene_id: A0A2J6S2S6
symbol: A0A2J6S2S6
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.


ensembl_gene_id: A0A2J6S2T2
symbol: A0A2J6S2T2
gene_biotype: protein_coding
description:
  Mitochondrial putative homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: A0A2J6S2T5
symbol: A0A2J6S2T5
gene_biotype: protein_coding
description:
  N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.


ensembl_gene_id: A0A2J6S2V9
symbol: A0A2J6S2V9
gene_biotype: protein_coding
description:
  Putative FAD binding oxidoreductase; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.


ensembl_gene_id: A0A2J6S2Y9
symbol: A0A2J6S2Y9
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A2J6S308
symbol: A0A2J6S308
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


ensembl_gene_id: A0A2J6S350
symbol: A0A2J6S350
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 7A; This small integral protein plays a role in holoenzyme assembly or stability.


ensembl_gene_id: A0A2J6S367
symbol: A0A2J6S367
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6S381
symbol: A0A2J6S381
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.


ensembl_gene_id: A0A2J6S396
symbol: A0A2J6S396
gene_biotype: protein_coding
description:
  U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.


ensembl_gene_id: A0A2J6S3A6
symbol: A0A2J6S3A6
gene_biotype: protein_coding
description:
  Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.


ensembl_gene_id: A0A2J6S3C2
symbol: A0A2J6S3C2
gene_biotype: protein_coding
description:
  Plasma membrane fusion protein PRM1; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event; Belongs to the PRM1 family.


ensembl_gene_id: A0A2J6S3C7
symbol: A0A2J6S3C7
gene_biotype: protein_coding
description:
  Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.


ensembl_gene_id: A0A2J6S3F1
symbol: NTH1
gene_biotype: protein_coding
description:
  Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.


ensembl_gene_id: A0A2J6S3G0
symbol: A0A2J6S3G0
gene_biotype: protein_coding
description:
  Repressor of RNA polymerase III transcription MAF1; Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA. Belongs to the MAF1 family.


ensembl_gene_id: A0A2J6S3G9
symbol: A0A2J6S3G9
gene_biotype: protein_coding
description:
  Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.


ensembl_gene_id: A0A2J6S3J6
symbol: A0A2J6S3J6
gene_biotype: protein_coding
description:
  S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: A0A2J6S3M4
symbol: A0A2J6S3M4
gene_biotype: protein_coding
description:
  GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.


ensembl_gene_id: A0A2J6S442
symbol: A0A2J6S442
gene_biotype: protein_coding
description:
  2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.


ensembl_gene_id: A0A2J6S482
symbol: A0A2J6S482
gene_biotype: protein_coding
description:
  Putative lipid-transfer protein, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A2J6S4G0
symbol: A0A2J6S4G0
gene_biotype: protein_coding
description:
  Acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A2J6S4Q4
symbol: A0A2J6S4Q4
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6S5F4
symbol: A0A2J6S5F4
gene_biotype: protein_coding
description:
  Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: A0A2J6S5Q7
symbol: AAH1
gene_biotype: protein_coding
description:
  Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.


ensembl_gene_id: A0A2J6S5R8
symbol: A0A2J6S5R8
gene_biotype: protein_coding
description:
  Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.


ensembl_gene_id: A0A2J6S5T8
symbol: A0A2J6S5T8
gene_biotype: protein_coding
description:
  Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A2J6S5U5
symbol: A0A2J6S5U5
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.


ensembl_gene_id: A0A2J6S5Y0
symbol: A0A2J6S5Y0
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: A0A2J6S5Z5
symbol: A0A2J6S5Z5
gene_biotype: protein_coding
description:
  DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.


ensembl_gene_id: A0A2J6S624
symbol: A0A2J6S624
gene_biotype: protein_coding
description:
  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A2J6S667
symbol: A0A2J6S667
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.


ensembl_gene_id: A0A2J6S672
symbol: NCS6
gene_biotype: protein_coding
description:
  Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.


ensembl_gene_id: A0A2J6S690
symbol: A0A2J6S690
gene_biotype: protein_coding
description:
  Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.


ensembl_gene_id: A0A2J6S6C2
symbol: A0A2J6S6C2
gene_biotype: protein_coding
description:
  Putative 1-aminocyclopropane-1-carboxylate oxidase; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: A0A2J6S6C9
symbol: A0A2J6S6C9
gene_biotype: protein_coding
description:
  Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.


ensembl_gene_id: A0A2J6S6E2
symbol: A0A2J6S6E2
gene_biotype: protein_coding
description:
  Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.


ensembl_gene_id: A0A2J6S6G0
symbol: A0A2J6S6G0
gene_biotype: protein_coding
description:
  Putative high-affinity glucose transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6S6M3
symbol: A0A2J6S6M3
gene_biotype: protein_coding
description:
  SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.


ensembl_gene_id: A0A2J6S6P1
symbol: A0A2J6S6P1
gene_biotype: protein_coding
description:
  Mitochondrial cytochrome c oxidase subunit VIa; Belongs to the cytochrome c oxidase subunit 6A family.


ensembl_gene_id: A0A2J6S6P4
symbol: A0A2J6S6P4
gene_biotype: protein_coding
description:
  Short chain dehydrogenase/reductase-like protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6S6R2
symbol: A0A2J6S6R2
gene_biotype: protein_coding
description:
  Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. Belongs to the acid sphingomyelinase family.


ensembl_gene_id: A0A2J6S6R3
symbol: MET3
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.


ensembl_gene_id: A0A2J6S6U9
symbol: A0A2J6S6U9
gene_biotype: protein_coding
description:
  Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.


ensembl_gene_id: A0A2J6S6V3
symbol: A0A2J6S6V3
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: A0A2J6S6V5
symbol: A0A2J6S6V5
gene_biotype: protein_coding
description:
  Mitochondrial carrier protein-like protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A2J6S6Y7
symbol: A0A2J6S6Y7
gene_biotype: protein_coding
description:
  Fatty acid synthase-like protein; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.


ensembl_gene_id: A0A2J6S6Y8
symbol: A0A2J6S6Y8
gene_biotype: protein_coding
description:
  Fatty acid synthase-like protein subunit beta; Belongs to the fungal fatty acid synthetase subunit beta family.


ensembl_gene_id: A0A2J6S764
symbol: MEF2
gene_biotype: protein_coding
description:
  Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: A0A2J6S772
symbol: A0A2J6S772
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Belongs to the VPS17 family.


ensembl_gene_id: A0A2J6S7B7
symbol: A0A2J6S7B7
gene_biotype: protein_coding
description:
  Putative retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A2J6S7C1
symbol: TAH18
gene_biotype: protein_coding
description:
  NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: A0A2J6S7H2
symbol: A0A2J6S7H2
gene_biotype: protein_coding
description:
  N2,N2-dimethylguanosine tRNA methyltransferas-like protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.


ensembl_gene_id: A0A2J6S7K0
symbol: A0A2J6S7K0
gene_biotype: protein_coding
description:
  Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates  [...]


ensembl_gene_id: A0A2J6S819
symbol: A0A2J6S819
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.


ensembl_gene_id: A0A2J6S8B1
symbol: A0A2J6S8B1
gene_biotype: protein_coding
description:
  Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.


ensembl_gene_id: A0A2J6S8B6
symbol: A0A2J6S8B6
gene_biotype: protein_coding
description:
  Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.


ensembl_gene_id: A0A2J6S8F7
symbol: A0A2J6S8F7
gene_biotype: protein_coding
description:
  Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family.


ensembl_gene_id: A0A2J6S8I5
symbol: A0A2J6S8I5
gene_biotype: protein_coding
description:
  Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A2J6S8L1
symbol: A0A2J6S8L1
gene_biotype: protein_coding
description:
  Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.


ensembl_gene_id: A0A2J6S941
symbol: A0A2J6S941
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.


ensembl_gene_id: A0A2J6S942
symbol: A0A2J6S942
gene_biotype: protein_coding
description:
  Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.


ensembl_gene_id: A0A2J6S943
symbol: A0A2J6S943
gene_biotype: protein_coding
description:
  Protein ROT1; Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies; Belongs to the ROT1 family.


ensembl_gene_id: A0A2J6S964
symbol: A0A2J6S964
gene_biotype: protein_coding
description:
  Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.


ensembl_gene_id: A0A2J6S967
symbol: A0A2J6S967
gene_biotype: protein_coding
description:
  Ribosomal RNA-processing protein 8; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2. Belongs to the methyltransferase superfamily. RRP8 family.


ensembl_gene_id: A0A2J6S977
symbol: A0A2J6S977
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A2J6S979
symbol: A0A2J6S979
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: A0A2J6S9A8
symbol: TIF35
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.


ensembl_gene_id: A0A2J6S9C5
symbol: A0A2J6S9C5
gene_biotype: protein_coding
description:
  Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.


ensembl_gene_id: A0A2J6S9D0
symbol: A0A2J6S9D0
gene_biotype: protein_coding
description:
  Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.


ensembl_gene_id: A0A2J6S9F1
symbol: PIM1
gene_biotype: protein_coding
description:
  Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-.


ensembl_gene_id: A0A2J6S9K1
symbol: A0A2J6S9K1
gene_biotype: protein_coding
description:
  Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family.


ensembl_gene_id: A0A2J6S9L6
symbol: LSM4
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A2J6S9M1
symbol: A0A2J6S9M1
gene_biotype: protein_coding
description:
  Septin-domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A2J6S9W6
symbol: A0A2J6S9W6
gene_biotype: protein_coding
description:
  Exocyst complex protein EXO70; Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst. Belongs to the EXO70 family.


ensembl_gene_id: A0A2J6S9Z0
symbol: A0A2J6S9Z0
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6S9Z8
symbol: A0A2J6S9Z8
gene_biotype: protein_coding
description:
  Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: A0A2J6SA16
symbol: A0A2J6SA16
gene_biotype: protein_coding
description:
  KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.


ensembl_gene_id: A0A2J6SAB3
symbol: A0A2J6SAB3
gene_biotype: protein_coding
description:
  P-type cation exchange, alpha subunit of ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A2J6SAL5
symbol: A0A2J6SAL5
gene_biotype: protein_coding
description:
  GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.


ensembl_gene_id: A0A2J6SAL7
symbol: A0A2J6SAL7
gene_biotype: protein_coding
description:
  Sugar transporter STL1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A2J6SAM9
symbol: MED4
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6SAN7
symbol: A0A2J6SAN7
gene_biotype: protein_coding
description:
  DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.


ensembl_gene_id: A0A2J6SAR6
symbol: A0A2J6SAR6
gene_biotype: protein_coding
description:
  Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.


ensembl_gene_id: A0A2J6SBX0
symbol: A0A2J6SBX0
gene_biotype: protein_coding
description:
  Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.


ensembl_gene_id: A0A2J6SBX1
symbol: A0A2J6SBX1
gene_biotype: protein_coding
description:
  Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A2J6SBY6
symbol: L207DRAFT_3808
gene_biotype: protein_coding
description:
  Citrinin biosynthesis oxygenase CtnA; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: A0A2J6SC02
symbol: A0A2J6SC02
gene_biotype: protein_coding
description:
  RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.


ensembl_gene_id: A0A2J6SC08
symbol: A0A2J6SC08
gene_biotype: protein_coding
description:
  Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.


ensembl_gene_id: A0A2J6SC16
symbol: A0A2J6SC16
gene_biotype: protein_coding
description:
  Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).


ensembl_gene_id: A0A2J6SC31
symbol: A0A2J6SC31
gene_biotype: protein_coding
description:
  Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.


ensembl_gene_id: A0A2J6SC39
symbol: TRM8
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: A0A2J6SC46
symbol: A0A2J6SC46
gene_biotype: protein_coding
description:
  3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.


ensembl_gene_id: A0A2J6SC49
symbol: A0A2J6SC49
gene_biotype: protein_coding
description:
  Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.


ensembl_gene_id: A0A2J6SCC2
symbol: A0A2J6SCC2
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: A0A2J6SCH8
symbol: EFM7
gene_biotype: protein_coding
description:
  Protein N-terminal and lysine N-methyltransferase EFM7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono-and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.


ensembl_gene_id: A0A2J6SCJ6
symbol: A0A2J6SCJ6
gene_biotype: protein_coding
description:
  Endopolyphosphatase; Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.


ensembl_gene_id: A0A2J6SCJ7
symbol: A0A2J6SCJ7
gene_biotype: protein_coding
description:
  Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.


ensembl_gene_id: A0A2J6SCL7
symbol: ERB1
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.


ensembl_gene_id: A0A2J6SCP1
symbol: A0A2J6SCP1
gene_biotype: protein_coding
description:
  Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.


ensembl_gene_id: A0A2J6SCP6
symbol: A0A2J6SCP6
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.


ensembl_gene_id: A0A2J6SCS5
symbol: A0A2J6SCS5
gene_biotype: protein_coding
description:
  Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.


ensembl_gene_id: A0A2J6SCS9
symbol: A0A2J6SCS9
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.


ensembl_gene_id: A0A2J6SCU0
symbol: MED16
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A2J6SCU6
symbol: A0A2J6SCU6
gene_biotype: protein_coding
description:
  DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.


ensembl_gene_id: A0A2J6SCV7
symbol: A0A2J6SCV7
gene_biotype: protein_coding
description:
  GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.


ensembl_gene_id: A0A2J6SCZ4
symbol: LSM8
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A2J6SD12
symbol: A0A2J6SD12
gene_biotype: protein_coding
description:
  Protein transport protein SFT2; Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex. Belongs to the SFT2 family.


ensembl_gene_id: A0A2J6SD36
symbol: A0A2J6SD36
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A2J6SD52
symbol: A0A2J6SD52
gene_biotype: protein_coding
description:
  GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.


ensembl_gene_id: A0A2J6SD72
symbol: A0A2J6SD72
gene_biotype: protein_coding
description:
  Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.


ensembl_gene_id: A0A2J6SD83
symbol: A0A2J6SD83
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A2J6SDD5
symbol: A0A2J6SDD5
gene_biotype: protein_coding
description:
  Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.


ensembl_gene_id: A0A2J6SDG1
symbol: A0A2J6SDG1
gene_biotype: protein_coding
description:
  Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.


ensembl_gene_id: A0A2J6SDT4
symbol: A0A2J6SDT4
gene_biotype: protein_coding
description:
  Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.


ensembl_gene_id: A0A2J6SDT9
symbol: A0A2J6SDT9
gene_biotype: protein_coding
description:
  Stress response protein NST1; May act as a negative regulator of salt tolerance. Belongs to the NST1 family.


ensembl_gene_id: A0A2J6SDZ0
symbol: A0A2J6SDZ0
gene_biotype: protein_coding
description:
  Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.


ensembl_gene_id: A0A2J6SE47
symbol: A0A2J6SE47
gene_biotype: protein_coding
description:
  Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family.


ensembl_gene_id: A0A2J6SE64
symbol: A0A2J6SE64
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


