# geneInfo

ensembl_gene_id: PMM47T1_00070
symbol: gabD
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase I; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PMM47T1_00075
symbol: EIK98389.1
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PMM47T1_00095
symbol: EIK98393.1
gene_biotype: protein_coding
description:
  PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: PMM47T1_00105
symbol: EIK98395.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1613 ABC-type sulfate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_00110
symbol: EIK98396.1
gene_biotype: protein_coding
description:
  Sulfate ABC transporter permease; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PMM47T1_00120
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PMM47T1_00130
symbol: EIK98400.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: PMM47T1_00135
symbol: EIK98401.1
gene_biotype: protein_coding
description:
  COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: PMM47T1_00145
symbol: EIK98403.1
gene_biotype: protein_coding
description:
  DNA-binding heavy metal response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_00150
symbol: EIK98404.1
gene_biotype: protein_coding
description:
  Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.


ensembl_gene_id: PMM47T1_00170
symbol: EIK98408.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PMM47T1_00175
symbol: EIK98409.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: PMM47T1_00180
symbol: EIK98410.1
gene_biotype: protein_coding
description:
  Sulfate ester ABC transporter periplasmic sulfate ester-binding protein AtsR; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_00200
symbol: EIK98414.1
gene_biotype: protein_coding
description:
  Sulfate ester transport system substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_00210
symbol: EIK98416.1
gene_biotype: protein_coding
description:
  TonB-dependent outermembrane receptor SftP; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: PMM47T1_00240
symbol: EIK98422.1
gene_biotype: protein_coding
description:
  Sigma-54 factor, interaction region; COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain.


ensembl_gene_id: PMM47T1_00245
symbol: EIK98423.1
gene_biotype: protein_coding
description:
  NLPA lipoprotein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.


ensembl_gene_id: PMM47T1_00260
symbol: EIK98426.1
gene_biotype: protein_coding
description:
  Glutamate ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: PMM47T1_00265
symbol: EIK98427.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_00270
symbol: EIK98428.1
gene_biotype: protein_coding
description:
  RND family efflux transporter MFP subunit; COG0845 Membrane-fusion protein; overlaps another CDS with the same product name; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_00280
symbol: EIK98430.1
gene_biotype: protein_coding
description:
  RND hydrophobe/amphiphile efflux-1 (HAE1) family transporter permease; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_00290
symbol: EIK98432.1
gene_biotype: protein_coding
description:
  D-methionine ABC transporter permease MetI; COG2011 ABC-type metal ion transport system, permease component.


ensembl_gene_id: PMM47T1_00295
symbol: metN-2
gene_biotype: protein_coding
description:
  D-methionine ABC transporter ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PMM47T1_00300
symbol: EIK98434.1
gene_biotype: protein_coding
description:
  Methionine ABC transporter substrate-binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.


ensembl_gene_id: PMM47T1_00305
symbol: EIK98435.1
gene_biotype: protein_coding
description:
  Putative monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_00325
symbol: EIK98439.1
gene_biotype: protein_coding
description:
  Putative amino-acid ABC transporter ATP-binding protein YecC; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: PMM47T1_00335
symbol: EIK98441.1
gene_biotype: protein_coding
description:
  Cystine transporter subunit; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PMM47T1_00350
symbol: EIK98444.1
gene_biotype: protein_coding
description:
  BCCT transporter; COG1292 Choline-glycine betaine transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: PMM47T1_00365
symbol: EIK98447.1
gene_biotype: protein_coding
description:
  Xenobiotic compound monooxygenase A subunit; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_00375
symbol: EIK98449.1
gene_biotype: protein_coding
description:
  Alkanesulfonate transporter substrate-binding subunit; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_00395
symbol: tauB
gene_biotype: protein_coding
description:
  Taurine transporter ATP-binding subunit; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: PMM47T1_00410
symbol: EIK98456.1
gene_biotype: protein_coding
description:
  Putative phosphorous compounds metabolism-like protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_00430
symbol: EIK98460.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, aliphatic sulfonates; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_00435
symbol: ssuD
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: PMM47T1_00445
symbol: ssuB
gene_biotype: protein_coding
description:
  Aliphatic sulfonates transport ATP-binding subunit; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PMM47T1_00460
symbol: EIK98466.1
gene_biotype: protein_coding
description:
  PspA family protein; COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription.


ensembl_gene_id: PMM47T1_00465
symbol: EIK98467.1
gene_biotype: protein_coding
description:
  Putative transmembrane rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).


ensembl_gene_id: PMM47T1_00510
symbol: EIK98476.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PMM47T1_00520
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PMM47T1_00525
symbol: EIK98479.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: PMM47T1_00570
symbol: EIK98488.1
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PMM47T1_00580
symbol: EIK98490.1
gene_biotype: protein_coding
description:
  Hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_00590
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: PMM47T1_00595
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: PMM47T1_00610
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: PMM47T1_00615
symbol: EIK98497.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: PMM47T1_00625
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: PMM47T1_00630
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: PMM47T1_00650
symbol: EIK98504.1
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_00660
symbol: EIK98506.1
gene_biotype: protein_coding
description:
  Putative cation ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: PMM47T1_00685
symbol: EIK98511.1
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: PMM47T1_00690
symbol: EIK98512.1
gene_biotype: protein_coding
description:
  Putative symporter membrane protein; COG1823 Predicted Na+/dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PMM47T1_00730
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: PMM47T1_00750
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: PMM47T1_00790
symbol: EIK98530.1
gene_biotype: protein_coding
description:
  Methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: PMM47T1_00805
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: PMM47T1_00810
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: PMM47T1_00815
symbol: EIK98535.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: PMM47T1_00820
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: PMM47T1_00825
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: PMM47T1_00840
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: PMM47T1_00845
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: PMM47T1_00855
symbol: EIK98543.1
gene_biotype: protein_coding
description:
  HemN family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: PMM47T1_00860
symbol: EIK98544.1
gene_biotype: protein_coding
description:
  dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: PMM47T1_00875
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: PMM47T1_00885
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: PMM47T1_00890
symbol: EIK98550.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: PMM47T1_00920
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: PMM47T1_00930
symbol: EIK98558.1
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: PMM47T1_00935
symbol: EIK98559.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: PMM47T1_00945
symbol: gshB
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: PMM47T1_00970
symbol: EIK98566.1
gene_biotype: protein_coding
description:
  CheA Signal transduction histidine kinase (STHK); COG0643 Chemotaxis protein histidine kinase and related kinases.


ensembl_gene_id: PMM47T1_00985
symbol: mdcB
gene_biotype: protein_coding
description:
  triphosphoribosyl-dephospho-CoA synthase; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.


ensembl_gene_id: PMM47T1_00990
symbol: mdcC
gene_biotype: protein_coding
description:
  Malonate decarboxylase subunit delta; Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.


ensembl_gene_id: PMM47T1_01030
symbol: EIK98578.1
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: PMM47T1_01035
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: PMM47T1_01050
symbol: rhlE
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase-like protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: PMM47T1_01055
symbol: EIK98583.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_01060
symbol: EIK98584.1
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: PMM47T1_01065
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: PMM47T1_01095
symbol: ligB
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigB; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: PMM47T1_01105
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: PMM47T1_01115
symbol: EIK98595.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: PMM47T1_01120
symbol: EIK98596.1
gene_biotype: protein_coding
description:
  D-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: PMM47T1_01140
symbol: EIK98600.1
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: PMM47T1_01155
symbol: EIK98603.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.


ensembl_gene_id: PMM47T1_01195
symbol: EIK98611.1
gene_biotype: protein_coding
description:
  EmrB/QacA family drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_01200
symbol: betA
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: PMM47T1_01205
symbol: betB
gene_biotype: protein_coding
description:
  Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: PMM47T1_01215
symbol: EIK98615.1
gene_biotype: protein_coding
description:
  Betaine/carnitine/choline family transporter; COG1292 Choline-glycine betaine transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: PMM47T1_01220
symbol: EIK98616.1
gene_biotype: protein_coding
description:
  glycine/betaine/L-proline ABC transporter ATP-binding protein; COG4175 ABC-type proline/glycine betaine transport system, ATPase component.


ensembl_gene_id: PMM47T1_01225
symbol: EIK98617.1
gene_biotype: protein_coding
description:
  Choline ABC transporter permease; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: PMM47T1_01230
symbol: EIK98618.1
gene_biotype: protein_coding
description:
  Glycine/betaine ABC transporter substrate-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_01240
symbol: EIK98620.1
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: PMM47T1_01275
symbol: lcdH
gene_biotype: protein_coding
description:
  3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.


ensembl_gene_id: PMM47T1_01285
symbol: EIK98629.1
gene_biotype: protein_coding
description:
  QAT family ABC transporter substrate-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_01340
symbol: EIK98640.1
gene_biotype: protein_coding
description:
  Putative iron/sulfur-binding protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_01370
symbol: EIK98646.1
gene_biotype: protein_coding
description:
  Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: PMM47T1_01375
symbol: glyA-2
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: PMM47T1_01390
symbol: EIK98650.1
gene_biotype: protein_coding
description:
  Sarcosine oxidase subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.


ensembl_gene_id: PMM47T1_01400
symbol: purU-2
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: PMM47T1_01415
symbol: EIK98655.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PMM47T1_01470
symbol: EIK98666.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein (cNMP-bd) protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains.


ensembl_gene_id: PMM47T1_01480
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: PMM47T1_01495
symbol: srkA
gene_biotype: protein_coding
description:
  Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: PMM47T1_01510
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: PMM47T1_01515
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: PMM47T1_01520
symbol: EIK98676.1
gene_biotype: protein_coding
description:
  Putative biotin biosynthesis-like protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_01525
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: PMM47T1_01530
symbol: bioD
gene_biotype: protein_coding
description:
  Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: PMM47T1_01565
symbol: pqqE
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: PMM47T1_01570
symbol: pqqD
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqD; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.


ensembl_gene_id: PMM47T1_01575
symbol: pqqC
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: PMM47T1_01580
symbol: pqqB
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqB; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: PMM47T1_01585
symbol: pqqA
gene_biotype: protein_coding
description:
  Coenzyme PQQ biosynthesis protein A; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide; Belongs to the PqqA family.


ensembl_gene_id: PMM47T1_01600
symbol: EIK98692.1
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthesis protein; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.


ensembl_gene_id: PMM47T1_01640
symbol: EIK98700.1
gene_biotype: protein_coding
description:
  Protein-tyrosine kinase; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.


ensembl_gene_id: PMM47T1_01645
symbol: EIK98701.1
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine protein phosphatase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: PMM47T1_01655
symbol: EIK98703.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: PMM47T1_01660
symbol: EIK98704.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PMM47T1_01700
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: PMM47T1_01705
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: PMM47T1_01715
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: PMM47T1_01720
symbol: plsY
gene_biotype: protein_coding
description:
  Putative glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: PMM47T1_01725
symbol: EIK98717.1
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: PMM47T1_01730
symbol: EIK98718.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: PMM47T1_01735
symbol: cca
gene_biotype: protein_coding
description:
  CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.


ensembl_gene_id: PMM47T1_01755
symbol: glpE
gene_biotype: protein_coding
description:
  Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: PMM47T1_01760
symbol: apaH
gene_biotype: protein_coding
description:
  Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: PMM47T1_01770
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: PMM47T1_01775
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: PMM47T1_01780
symbol: surA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: PMM47T1_01785
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: PMM47T1_01795
symbol: EIK98731.1
gene_biotype: protein_coding
description:
  Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: PMM47T1_01805
symbol: EIK98733.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_01810
symbol: EIK98734.1
gene_biotype: protein_coding
description:
  Putative two-component sensor, near polyamine transporter; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_01820
symbol: potA-2
gene_biotype: protein_coding
description:
  PotA protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PMM47T1_01835
symbol: EIK98739.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: PMM47T1_01850
symbol: EIK98742.1
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: PMM47T1_01855
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: PMM47T1_01865
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: PMM47T1_01880
symbol: EIK98748.1
gene_biotype: protein_coding
description:
  DNA-binding transcriptional dual regulator Crp; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: PMM47T1_01890
symbol: coq7
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein COQ7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: PMM47T1_01895
symbol: EIK98751.1
gene_biotype: protein_coding
description:
  Histidine triad (HIT) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: PMM47T1_01900
symbol: EIK98752.1
gene_biotype: protein_coding
description:
  COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_01920
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: PMM47T1_01925
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: PMM47T1_01930
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: PMM47T1_01940
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: PMM47T1_01959
symbol: EIK97991.1
gene_biotype: protein_coding
description:
  PTS system subunit IIA; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: PMM47T1_01969
symbol: EIK97993.1
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: PMM47T1_01974
symbol: EIK97994.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component.


ensembl_gene_id: PMM47T1_01979
symbol: lptA
gene_biotype: protein_coding
description:
  OstA family protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: PMM47T1_01984
symbol: lptC
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.


ensembl_gene_id: PMM47T1_01989
symbol: EIK97997.1
gene_biotype: protein_coding
description:
  Phosphatase, YrbI family protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: PMM47T1_01994
symbol: EIK97998.1
gene_biotype: protein_coding
description:
  Arabinose 5-phosphate isomerase; COG0794 Predicted sugar phosphate isomerase involved in capsule formation.


ensembl_gene_id: PMM47T1_01999
symbol: EIK97999.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.


ensembl_gene_id: PMM47T1_02004
symbol: EIK98000.1
gene_biotype: protein_coding
description:
  Protein YrbE; COG0767 ABC-type transport system involved in resistance to organic solvents, permease component.


ensembl_gene_id: PMM47T1_02009
symbol: EIK98001.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: PMM47T1_02014
symbol: EIK98002.1
gene_biotype: protein_coding
description:
  Toluene tolerance protein; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.


ensembl_gene_id: PMM47T1_02024
symbol: EIK98004.1
gene_biotype: protein_coding
description:
  Protein YrbA; COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family.


ensembl_gene_id: PMM47T1_02029
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: PMM47T1_02034
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: PMM47T1_02039
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: PMM47T1_02044
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: PMM47T1_02049
symbol: EIK98009.1
gene_biotype: protein_coding
description:
  Peptidase S1 and S6, chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: PMM47T1_02059
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: PMM47T1_02069
symbol: cysC
gene_biotype: protein_coding
description:
  Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: PMM47T1_02089
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PMM47T1_02114
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: PMM47T1_02124
symbol: EIK98024.1
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: PMM47T1_02129
symbol: EIK98025.1
gene_biotype: protein_coding
description:
  Ubiquinol--cytochrome C reductase, cytochrome B subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: PMM47T1_02154
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: PMM47T1_02159
symbol: EIK98031.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: PMM47T1_02169
symbol: rsmI
gene_biotype: protein_coding
description:
  rRNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: PMM47T1_02174
symbol: mraZ
gene_biotype: protein_coding
description:
  Cell division protein MraZ; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: PMM47T1_02179
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: PMM47T1_02184
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: PMM47T1_02189
symbol: ftsI
gene_biotype: protein_coding
description:
  Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: PMM47T1_02194
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: PMM47T1_02199
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: PMM47T1_02204
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: PMM47T1_02209
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: PMM47T1_02214
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: PMM47T1_02219
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: PMM47T1_02229
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: PMM47T1_02234
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: PMM47T1_02239
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: PMM47T1_02244
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: PMM47T1_02249
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: PMM47T1_02259
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: PMM47T1_02264
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: PMM47T1_02284
symbol: EIK98056.1
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: PMM47T1_02294
symbol: EIK98058.1
gene_biotype: protein_coding
description:
  Putative nucleotide-binding protein; COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family.


ensembl_gene_id: PMM47T1_02309
symbol: EIK98061.1
gene_biotype: protein_coding
description:
  methylated-DNA-(protein)-cysteine S-methyltransferase; COG3695 Predicted methylated DNA-protein cysteine methyltransferase.


ensembl_gene_id: PMM47T1_02329
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: PMM47T1_02334
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: PMM47T1_02339
symbol: EIK98067.1
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_02359
symbol: EIK98071.1
gene_biotype: protein_coding
description:
  COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_02379
symbol: EIK98075.1
gene_biotype: protein_coding
description:
  Putative thiol oxidoreductase with 2 cytochrome c heme-binding sites; COG3488 Predicted thiol oxidoreductase.


ensembl_gene_id: PMM47T1_02394
symbol: EIK98078.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: PMM47T1_02404
symbol: argP
gene_biotype: protein_coding
description:
  Chromosome replication initiation inhibitor protein; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PMM47T1_02459
symbol: EIK98091.1
gene_biotype: protein_coding
description:
  Phospholipase family protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: PMM47T1_02469
symbol: EIK98093.1
gene_biotype: protein_coding
description:
  COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis.


ensembl_gene_id: PMM47T1_02474
symbol: EIK98094.1
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: PMM47T1_02484
symbol: EIK98096.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: PMM47T1_02509
symbol: EIK98101.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: PMM47T1_02604
symbol: EIK98120.1
gene_biotype: protein_coding
description:
  Beta-ketoadipyl CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: PMM47T1_02609
symbol: EIK98121.1
gene_biotype: protein_coding
description:
  metabolite:H+ symporter (MHS) family MFS transporter protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_02619
symbol: EIK98123.1
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactonase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_02624
symbol: EIK98124.1
gene_biotype: protein_coding
description:
  4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


ensembl_gene_id: PMM47T1_02644
symbol: EIK98128.1
gene_biotype: protein_coding
description:
  RND family efflux transporter MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_02669
symbol: EIK98133.1
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_02694
symbol: EIK98138.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: PMM47T1_02719
symbol: EIK98143.1
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: PMM47T1_02729
symbol: EIK98145.1
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: PMM47T1_02739
symbol: EIK98147.1
gene_biotype: protein_coding
description:
  beta-D-glucoside glucohydrolase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: PMM47T1_02744
symbol: EIK98148.1
gene_biotype: protein_coding
description:
  Regulatory protein LuxR; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PMM47T1_02809
symbol: EIK98159.1
gene_biotype: protein_coding
description:
  (R)-3-hydroxydecanoyl-ACP:CoA transacylase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_02814
symbol: EIK98160.1
gene_biotype: protein_coding
description:
  Ribosomal small subunit pseudouridine synthase A; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PMM47T1_02839
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: PMM47T1_02859
symbol: EIK98169.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_02909
symbol: EIK98179.1
gene_biotype: protein_coding
description:
  Protease Do; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: PMM47T1_02914
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: PMM47T1_02929
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: PMM47T1_02934
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: PMM47T1_02944
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: PMM47T1_02964
symbol: glyA-3
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: PMM47T1_02969
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: PMM47T1_02974
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: PMM47T1_02994
symbol: EIK98196.1
gene_biotype: protein_coding
description:
  COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PMM47T1_03004
symbol: cmoB
gene_biotype: protein_coding
description:
  tRNA mo(5)U34 methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: PMM47T1_03009
symbol: cmoA
gene_biotype: protein_coding
description:
  tRNA (cmo5U34)-methyltransferase CmoA; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: PMM47T1_03019
symbol: lon
gene_biotype: protein_coding
description:
  Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: PMM47T1_03079
symbol: EIK98213.1
gene_biotype: protein_coding
description:
  Peptidase M48, Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: PMM47T1_03084
symbol: EIK98214.1
gene_biotype: protein_coding
description:
  SirA family protein; COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: PMM47T1_03104
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: PMM47T1_03119
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: PMM47T1_03174
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: PMM47T1_03309
symbol: aceK
gene_biotype: protein_coding
description:
  Bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: PMM47T1_03354
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: PMM47T1_03379
symbol: EIK98273.1
gene_biotype: protein_coding
description:
  Cys/Met metabolism pyridoxal-phosphate-dependent protein; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.


ensembl_gene_id: PMM47T1_03404
symbol: EIK98278.1
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: PMM47T1_03459
symbol: EIK98289.1
gene_biotype: protein_coding
description:
  COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; Belongs to the UPF0149 family.


ensembl_gene_id: PMM47T1_03539
symbol: EIK98305.1
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: PMM47T1_03549
symbol: EIK98307.1
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: PMM47T1_03559
symbol: EIK98309.1
gene_biotype: protein_coding
description:
  COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: PMM47T1_03569
symbol: EIK98311.1
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_03579
symbol: dctA
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PMM47T1_03594
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: PMM47T1_03624
symbol: EIK98322.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins.


ensembl_gene_id: PMM47T1_03639
symbol: EIK98325.1
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PMM47T1_03674
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA m(5)U1939 methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: PMM47T1_03679
symbol: EIK98333.1
gene_biotype: protein_coding
description:
  RelA protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: PMM47T1_03699
symbol: EIK98337.1
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: PMM47T1_03709
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: PMM47T1_03719
symbol: EIK98341.1
gene_biotype: protein_coding
description:
  OmpA/MotB domain-containing protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: PMM47T1_03724
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: PMM47T1_03734
symbol: EIK98344.1
gene_biotype: protein_coding
description:
  Putative LuxR family regulatory protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PMM47T1_03744
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: PMM47T1_03749
symbol: EIK98347.1
gene_biotype: protein_coding
description:
  Protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: PMM47T1_03754
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: PMM47T1_03759
symbol: EIK98349.1
gene_biotype: protein_coding
description:
  ATP-binding Mrp/Nbp35 family protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: PMM47T1_03789
symbol: EIK98355.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter ATP-binding protein; COG4598 ABC-type histidine transport system, ATPase component.


ensembl_gene_id: PMM47T1_03799
symbol: EIK98357.1
gene_biotype: protein_coding
description:
  Histidine/lysine/arginine/ornithine ABC transporter permease HisM; COG4160 ABC-type arginine/histidine transport system, permease component.


ensembl_gene_id: PMM47T1_03809
symbol: EIK98359.1
gene_biotype: protein_coding
description:
  COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PMM47T1_03819
symbol: EIK98361.1
gene_biotype: protein_coding
description:
  mRNA 3''''-end processing factor; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: PMM47T1_03864
symbol: EIK98370.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter/malic acid transport protein; COG1275 Tellurite resistance protein and related permeases.


ensembl_gene_id: PMM47T1_03869
symbol: EIK98371.1
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_03924
symbol: EIK97627.1
gene_biotype: protein_coding
description:
  Glucose ABC transporter, periplasmic glucose-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: PMM47T1_03939
symbol: EIK97630.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter ATP-binding protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_03949
symbol: EIK97632.1
gene_biotype: protein_coding
description:
  Aldose 1-epimerase; COG0676 Uncharacterized enzymes related to aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family.


ensembl_gene_id: PMM47T1_03959
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: PMM47T1_04009
symbol: EIK97644.1
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_04014
symbol: EIK97645.1
gene_biotype: protein_coding
description:
  Putative Co/Zn/Cd efflux system membrane fusion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_04029
symbol: EIK97648.1
gene_biotype: protein_coding
description:
  GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: PMM47T1_04039
symbol: EIK97650.1
gene_biotype: protein_coding
description:
  Anaerobic nitric oxide reductase transcription regulator; COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains.


ensembl_gene_id: PMM47T1_04044
symbol: EIK97651.1
gene_biotype: protein_coding
description:
  Bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; COG1017 Hemoglobin-like flavoprotein; Belongs to the globin family.


ensembl_gene_id: PMM47T1_04049
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: PMM47T1_04059
symbol: EIK97654.1
gene_biotype: protein_coding
description:
  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: PMM47T1_04074
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: PMM47T1_04109
symbol: EIK97664.1
gene_biotype: protein_coding
description:
  MCP methyltransferase/methylesterase; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.


ensembl_gene_id: PMM47T1_04134
symbol: EIK97669.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PMM47T1_04199
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: PMM47T1_04204
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: PMM47T1_04209
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: PMM47T1_04214
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: PMM47T1_04219
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: PMM47T1_04229
symbol: EIK97688.1
gene_biotype: protein_coding
description:
  Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: PMM47T1_04234
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: PMM47T1_04244
symbol: EIK97691.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly transcription factor IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: PMM47T1_04249
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: PMM47T1_04254
symbol: EIK97693.1
gene_biotype: protein_coding
description:
  Scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: PMM47T1_04259
symbol: EIK97694.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: PMM47T1_04264
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: PMM47T1_04269
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: PMM47T1_04284
symbol: ndk
gene_biotype: protein_coding
description:
  Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: PMM47T1_04289
symbol: rlmN
gene_biotype: protein_coding
description:
  2-vinyl bacteriochlorophyllide hydratase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: PMM47T1_04304
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: PMM47T1_04319
symbol: bamB
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PMM47T1_04324
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: PMM47T1_04339
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: PMM47T1_04349
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: PMM47T1_04369
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: PMM47T1_04379
symbol: EIK97718.1
gene_biotype: protein_coding
description:
  Putative phage-related integrase protein; COG0582 Integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: PMM47T1_04409
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PMM47T1_04414
symbol: mltF
gene_biotype: protein_coding
description:
  Membrane-bound lytic transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: PMM47T1_04419
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: PMM47T1_04429
symbol: EIK97728.1
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin outer membrane protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: PMM47T1_04439
symbol: EIK97730.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate--protein phosphotransferase, IIBC subunit; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.


ensembl_gene_id: PMM47T1_04489
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: PMM47T1_04509
symbol: EIK97744.1
gene_biotype: protein_coding
description:
  Cytochrome c assembly protein; COG4137 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: PMM47T1_04514
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: PMM47T1_04524
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: PMM47T1_04529
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: PMM47T1_04534
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: PMM47T1_04544
symbol: EIK97751.1
gene_biotype: protein_coding
description:
  CPA2 family transporter; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: PMM47T1_04549
symbol: xerD
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: PMM47T1_04554
symbol: EIK97753.1
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: PMM47T1_04569
symbol: EIK97756.1
gene_biotype: protein_coding
description:
  Sensory box histidine kinase/response regulator; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_04579
symbol: EIK97758.1
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PMM47T1_04609
symbol: mdoD
gene_biotype: protein_coding
description:
  Glucan biosynthesis protein D; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs). Belongs to the OpgD/OpgG family.


ensembl_gene_id: PMM47T1_04629
symbol: EIK97768.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: PMM47T1_04639
symbol: EIK97770.1
gene_biotype: protein_coding
description:
  COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_04709
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis-specific methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: PMM47T1_04714
symbol: EIK97785.1
gene_biotype: protein_coding
description:
  Response regulator/diguanylate cyclase domain-containing protein; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.


ensembl_gene_id: PMM47T1_04724
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: PMM47T1_04764
symbol: EIK97795.1
gene_biotype: protein_coding
description:
  OmpA family lipoprotein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: PMM47T1_04779
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: PMM47T1_04784
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: PMM47T1_04789
symbol: EIK97800.1
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: PMM47T1_04824
symbol: EIK97807.1
gene_biotype: protein_coding
description:
  Putative lipoprotein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_04829
symbol: EIK97808.1
gene_biotype: protein_coding
description:
  Putative transporter-like membrane protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_04864
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: PMM47T1_04904
symbol: EIK97823.1
gene_biotype: protein_coding
description:
  ThiF family protein; COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1.


ensembl_gene_id: PMM47T1_04919
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: PMM47T1_04924
symbol: EIK97827.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: PMM47T1_04929
symbol: EIK97828.1
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: PMM47T1_04944
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: PMM47T1_04949
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: PMM47T1_04959
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: PMM47T1_04969
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: PMM47T1_04974
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: PMM47T1_04984
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: PMM47T1_04994
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PMM47T1_05004
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: PMM47T1_05009
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: PMM47T1_05014
symbol: lpxA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PMM47T1_05019
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PMM47T1_05034
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: PMM47T1_05039
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: PMM47T1_05044
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: PMM47T1_05049
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.


ensembl_gene_id: PMM47T1_05054
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: PMM47T1_05059
symbol: ftsB
gene_biotype: protein_coding
description:
  Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: PMM47T1_05064
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: PMM47T1_05069
symbol: EIK97856.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family, in formaldehyde detoxification operon; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PMM47T1_05074
symbol: EIK97857.1
gene_biotype: protein_coding
description:
  COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: PMM47T1_05084
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: PMM47T1_05089
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: PMM47T1_05094
symbol: surE
gene_biotype: protein_coding
description:
  5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: PMM47T1_05099
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: PMM47T1_05109
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: PMM47T1_05114
symbol: EIK97865.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: PMM47T1_05119
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: PMM47T1_05144
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: PMM47T1_05179
symbol: EIK97878.1
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PMM47T1_05184
symbol: EIK97879.1
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: PMM47T1_05194
symbol: EIK97881.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD/NAD(P)-binding subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: PMM47T1_05214
symbol: EIK97885.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases.


ensembl_gene_id: PMM47T1_05224
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: PMM47T1_05229
symbol: kup
gene_biotype: protein_coding
description:
  Low affinity potassium transporter protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: PMM47T1_05244
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: PMM47T1_05254
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyla [...]


ensembl_gene_id: PMM47T1_05289
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: PMM47T1_05299
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: PMM47T1_05304
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: PMM47T1_05309
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: PMM47T1_05319
symbol: tolQ
gene_biotype: protein_coding
description:
  Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: PMM47T1_05324
symbol: tolR
gene_biotype: protein_coding
description:
  TolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: PMM47T1_05334
symbol: tolB
gene_biotype: protein_coding
description:
  Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: PMM47T1_05339
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: PMM47T1_05344
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: PMM47T1_05349
symbol: queE
gene_biotype: protein_coding
description:
  Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: PMM47T1_05354
symbol: queC
gene_biotype: protein_coding
description:
  ExsB family transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: PMM47T1_05389
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: PMM47T1_05399
symbol: EIK97922.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_05409
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: PMM47T1_05424
symbol: EIK97927.1
gene_biotype: protein_coding
description:
  Putative sodium/solute symporter; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PMM47T1_05429
symbol: EIK97928.1
gene_biotype: protein_coding
description:
  Putative transmembrane transport protein; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: PMM47T1_05439
symbol: EIK97930.1
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: PMM47T1_05449
symbol: EIK97932.1
gene_biotype: protein_coding
description:
  PAS/PAC sensor-containing methyl-accepting chemotaxis sensory transducer; COG2202 FOG: PAS/PAC domain.


ensembl_gene_id: PMM47T1_05464
symbol: EIK97935.1
gene_biotype: protein_coding
description:
  Polyamine ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_05469
symbol: EIK97936.1
gene_biotype: protein_coding
description:
  Putative ABC transporter membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: PMM47T1_05484
symbol: EIK97939.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: PMM47T1_05514
symbol: EIK97945.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PMM47T1_05519
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: PMM47T1_05529
symbol: minC
gene_biotype: protein_coding
description:
  Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: PMM47T1_05534
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: PMM47T1_05569
symbol: EIK97956.1
gene_biotype: protein_coding
description:
  Putative glycine betaine-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_05579
symbol: actP
gene_biotype: protein_coding
description:
  Acetate permease; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PMM47T1_05659
symbol: EIK97974.1
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_05669
symbol: EIK97976.1
gene_biotype: protein_coding
description:
  Type I secretion system ATPase; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: PMM47T1_05801
symbol: dsbB-2
gene_biotype: protein_coding
description:
  Disulfide bond formation protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: PMM47T1_05816
symbol: EIK97276.1
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: PMM47T1_05821
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: PMM47T1_05826
symbol: EIK97278.1
gene_biotype: protein_coding
description:
  Response regulator receiver:LytTr DNA-binding region; COG3279 Response regulator of the LytR/AlgR family.


ensembl_gene_id: PMM47T1_05831
symbol: EIK97279.1
gene_biotype: protein_coding
description:
  Alginate biosynthesis protein AlgZ/FimS; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.


ensembl_gene_id: PMM47T1_05861
symbol: cyaY
gene_biotype: protein_coding
description:
  Frataxin-like protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: PMM47T1_05871
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: PMM47T1_05876
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: PMM47T1_05886
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: PMM47T1_05981
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: PMM47T1_05986
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: PMM47T1_06006
symbol: dadX
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: PMM47T1_06036
symbol: EIK97320.1
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: PMM47T1_06041
symbol: EIK97321.1
gene_biotype: protein_coding
description:
  Phospholipase D/transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: PMM47T1_06071
symbol: EIK97327.1
gene_biotype: protein_coding
description:
  Family 5 extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: PMM47T1_06096
symbol: EIK97332.1
gene_biotype: protein_coding
description:
  Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: PMM47T1_06101
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: PMM47T1_06111
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: PMM47T1_06121
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: PMM47T1_06131
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: PMM47T1_06146
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: PMM47T1_06151
symbol: EIK97343.1
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: PMM47T1_06186
symbol: EIK97350.1
gene_biotype: protein_coding
description:
  Oxidative stress regulatory protein OxyR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PMM47T1_06191
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PMM47T1_06201
symbol: EIK97353.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.


ensembl_gene_id: PMM47T1_06226
symbol: EIK97358.1
gene_biotype: protein_coding
description:
  Amino acid adenylation:thioester reductase; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: PMM47T1_06246
symbol: EIK97362.1
gene_biotype: protein_coding
description:
  TonB-dependent outermembrane ferrioxamine receptor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: PMM47T1_06276
symbol: EIK97368.1
gene_biotype: protein_coding
description:
  Secretion protein HlyD; COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_06296
symbol: iolG
gene_biotype: protein_coding
description:
  Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).


ensembl_gene_id: PMM47T1_06306
symbol: EIK97374.1
gene_biotype: protein_coding
description:
  DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: PMM47T1_06311
symbol: EIK97375.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the FAD-dependent oxidoreductase family.


ensembl_gene_id: PMM47T1_06321
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: PMM47T1_06326
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: PMM47T1_06346
symbol: EIK97382.1
gene_biotype: protein_coding
description:
  Putative transporter-like membrane protein; COG1253 Hemolysins and related proteins containing CBS domains.


ensembl_gene_id: PMM47T1_06366
symbol: pstB-2
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: PMM47T1_06376
symbol: EIK97388.1
gene_biotype: protein_coding
description:
  Putative phosphate ABC transporter membrane protein; COG4590 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: PMM47T1_06411
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: PMM47T1_06416
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: PMM47T1_06436
symbol: EIK97400.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PMM47T1_06441
symbol: EIK97401.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_06446
symbol: EIK97402.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: PMM47T1_06451
symbol: EIK97403.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_06481
symbol: nadX
gene_biotype: protein_coding
description:
  L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.


ensembl_gene_id: PMM47T1_06491
symbol: EIK97411.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: PMM47T1_06506
symbol: EIK97414.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_06536
symbol: EIK97420.1
gene_biotype: protein_coding
description:
  Aspartate racemase-like protein; COG1794 Aspartate racemase; Belongs to the aspartate/glutamate racemases family.


ensembl_gene_id: PMM47T1_06586
symbol: EIK97430.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PMM47T1_06656
symbol: pdxY
gene_biotype: protein_coding
description:
  Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: PMM47T1_06691
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: PMM47T1_06721
symbol: EIK97457.1
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: PMM47T1_06791
symbol: EIK97471.1
gene_biotype: protein_coding
description:
  Aldehyde oxidase and xanthine dehydrogenase family protein; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: PMM47T1_06796
symbol: EIK97472.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: PMM47T1_06801
symbol: EIK97473.1
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: PMM47T1_06836
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: PMM47T1_06851
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: PMM47T1_06856
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: PMM47T1_06861
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: PMM47T1_06866
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: PMM47T1_06871
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: PMM47T1_06876
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: PMM47T1_06881
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: PMM47T1_06886
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: PMM47T1_06891
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: PMM47T1_06901
symbol: EIK97493.1
gene_biotype: protein_coding
description:
  Chromosomal partitioning protein ParB; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: PMM47T1_06911
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: PMM47T1_06916
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: PMM47T1_06921
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: PMM47T1_06931
symbol: EIK97499.1
gene_biotype: protein_coding
description:
  Oxidoreductase molybdopterin binding domain-containing protein 1; COG2041 Sulfite oxidase and related enzymes.


ensembl_gene_id: PMM47T1_06941
symbol: EIK97501.1
gene_biotype: protein_coding
description:
  Transcriptional regulator ResD; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_06951
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: PMM47T1_06956
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: PMM47T1_06961
symbol: EIK97505.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: PMM47T1_06966
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: PMM47T1_06976
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: PMM47T1_06981
symbol: EIK97509.1
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: PMM47T1_06986
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: PMM47T1_06991
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PMM47T1_07061
symbol: trkA
gene_biotype: protein_coding
description:
  Potassium transporter peripheral membrane component; COG0569 K+ transport systems, NAD-binding component.


ensembl_gene_id: PMM47T1_07066
symbol: EIK97526.1
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: PMM47T1_07071
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: PMM47T1_07091
symbol: tsaC
gene_biotype: protein_coding
description:
  SUA5/yciO/yrdC; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: PMM47T1_07101
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: PMM47T1_07106
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: PMM47T1_07146
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: PMM47T1_07151
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: PMM47T1_07176
symbol: EIK97548.1
gene_biotype: protein_coding
description:
  Luciferase-like protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_07226
symbol: EIK97558.1
gene_biotype: protein_coding
description:
  Dual specificity phosphatase, catalytic domain-containing protein; COG2365 Protein tyrosine/serine phosphatase.


ensembl_gene_id: PMM47T1_07251
symbol: EIK97563.1
gene_biotype: protein_coding
description:
  Protein CynT; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: PMM47T1_07256
symbol: EIK97564.1
gene_biotype: protein_coding
description:
  Putative transporter-like membrane protein; COG0659 Sulfate permease and related transporters (MFS superfamily).


ensembl_gene_id: PMM47T1_07261
symbol: EIK97565.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: PMM47T1_07266
symbol: EIK97566.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: PMM47T1_07296
symbol: EIK97572.1
gene_biotype: protein_coding
description:
  Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly.


ensembl_gene_id: PMM47T1_07306
symbol: EIK97574.1
gene_biotype: protein_coding
description:
  COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: PMM47T1_07311
symbol: EIK97575.1
gene_biotype: protein_coding
description:
  Putative TonB-dependent receptor; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.


ensembl_gene_id: PMM47T1_07316
symbol: EIK97576.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG2011 ABC-type metal ion transport system, permease component.


ensembl_gene_id: PMM47T1_07321
symbol: metN
gene_biotype: protein_coding
description:
  DL-methionine transporter ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PMM47T1_07341
symbol: znuC
gene_biotype: protein_coding
description:
  Zinc ABC transporter ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: PMM47T1_07346
symbol: fur
gene_biotype: protein_coding
description:
  Transcriptional regulator np20; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: PMM47T1_07351
symbol: EIK97583.1
gene_biotype: protein_coding
description:
  High-affinity zinc ABC transporter periplasmic zinc-binding protein ZnuA; COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin.


ensembl_gene_id: PMM47T1_07356
symbol: thrB
gene_biotype: protein_coding
description:
  COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: PMM47T1_07366
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: PMM47T1_07371
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: PMM47T1_07401
symbol: EIK97593.1
gene_biotype: protein_coding
description:
  EAL domain-containing protein; COG4943 Predicted signal transduction protein containing sensor and EAL domains.


ensembl_gene_id: PMM47T1_07411
symbol: EIK97595.1
gene_biotype: protein_coding
description:
  Alginate biosynthesis transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: PMM47T1_07436
symbol: gltP
gene_biotype: protein_coding
description:
  Glutamate/aspartate:proton symporter; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.


ensembl_gene_id: PMM47T1_07526
symbol: EIK97616.1
gene_biotype: protein_coding
description:
  NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: PMM47T1_07531
symbol: EIK97617.1
gene_biotype: protein_coding
description:
  Pyridine proton-translocating NAD(P) transhydrogenase subunit; COG3288 NAD/NADP transhydrogenase alpha subunit.


ensembl_gene_id: PMM47T1_07551
symbol: EIK97621.1
gene_biotype: protein_coding
description:
  Family III CoA-transferase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: PMM47T1_07561
symbol: EIK96980.1
gene_biotype: protein_coding
description:
  General secretion pathway protein E; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: PMM47T1_07586
symbol: EIK96985.1
gene_biotype: protein_coding
description:
  Bcr/CflA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_07606
symbol: EIK96989.1
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_07641
symbol: EIK96996.1
gene_biotype: protein_coding
description:
  Sigma54-dependent activator protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: PMM47T1_07646
symbol: EIK96997.1
gene_biotype: protein_coding
description:
  Putative sigma-70 factor, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PMM47T1_07701
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: PMM47T1_07721
symbol: EIK97012.1
gene_biotype: protein_coding
description:
  Class V aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: PMM47T1_07726
symbol: EIK97013.1
gene_biotype: protein_coding
description:
  Aldolase II superfamily protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: PMM47T1_07741
symbol: arnT
gene_biotype: protein_coding
description:
  4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.


ensembl_gene_id: PMM47T1_07751
symbol: EIK97018.1
gene_biotype: protein_coding
description:
  Secreted pili protein involved in motility and biofilm formation; COG5430 Uncharacterized secreted protein.


ensembl_gene_id: PMM47T1_07756
symbol: EIK97019.1
gene_biotype: protein_coding
description:
  Vanillate O-demethylase oxygenase subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_07801
symbol: EIK97028.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_07836
symbol: EIK97035.1
gene_biotype: protein_coding
description:
  GDP-mannose pyrophosphatase NudK/conserved domain-containing protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: PMM47T1_07871
symbol: EIK97042.1
gene_biotype: protein_coding
description:
  Fusaric acid resistance protein; COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_07886
symbol: EIK97045.1
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase superfamily protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_07896
symbol: EIK97047.1
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter periplasmic molybdate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_07901
symbol: EIK97048.1
gene_biotype: protein_coding
description:
  Molybdate ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PMM47T1_07906
symbol: modC
gene_biotype: protein_coding
description:
  Protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: PMM47T1_07951
symbol: EIK97058.1
gene_biotype: protein_coding
description:
  Putative CoA transferase family protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: PMM47T1_07961
symbol: EIK97060.1
gene_biotype: protein_coding
description:
  Multidrug efflux RND transporter, membrane fusion protein MexE; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_08006
symbol: EIK97069.1
gene_biotype: protein_coding
description:
  Methylesterase, CheB-like protein; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.


ensembl_gene_id: PMM47T1_08041
symbol: EIK97076.1
gene_biotype: protein_coding
description:
  Putative ABC transporter mannitol-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: PMM47T1_08046
symbol: EIK97077.1
gene_biotype: protein_coding
description:
  Polyol ABC transporter permease MtlF; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: PMM47T1_08056
symbol: EIK97079.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_08081
symbol: EIK97084.1
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: PMM47T1_08091
symbol: EIK97086.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: PMM47T1_08231
symbol: thiM
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: PMM47T1_08236
symbol: EIK97115.1
gene_biotype: protein_coding
description:
  Allophanate hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: PMM47T1_08266
symbol: EIK97121.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_08281
symbol: EIK97124.1
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: PMM47T1_08291
symbol: prpB
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: PMM47T1_08311
symbol: EIK97130.1
gene_biotype: protein_coding
description:
  Response regulator receiver domain-containing protein; COG1982 Arginine/lysine/ornithine decarboxylases.


ensembl_gene_id: PMM47T1_08316
symbol: potE
gene_biotype: protein_coding
description:
  Putrescine transporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.


ensembl_gene_id: PMM47T1_08441
symbol: EIK97156.1
gene_biotype: protein_coding
description:
  EmrB/QacA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_08446
symbol: EIK97157.1
gene_biotype: protein_coding
description:
  Multidrug resistance protein (hlyD family), emrA-like secretion; COG1566 Multidrug resistance efflux pump.


ensembl_gene_id: PMM47T1_08461
symbol: EIK97160.1
gene_biotype: protein_coding
description:
  Nitrate ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PMM47T1_08486
symbol: EIK97165.1
gene_biotype: protein_coding
description:
  Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PMM47T1_08506
symbol: EIK97169.1
gene_biotype: protein_coding
description:
  Isoquinoline 1-oxidoreductase subunit beta; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: PMM47T1_08511
symbol: EIK97170.1
gene_biotype: protein_coding
description:
  Isoquinoline 1-oxidoreductase subunit alpha; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: PMM47T1_08536
symbol: EIK97175.1
gene_biotype: protein_coding
description:
  Vanillate demethylase oxygenase subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_08566
symbol: selU
gene_biotype: protein_coding
description:
  tRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: PMM47T1_08606
symbol: EIK97189.1
gene_biotype: protein_coding
description:
  Rieske 2Fe-2S family protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_08626
symbol: EIK97193.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG3565 Predicted dioxygenase of extradiol dioxygenase family.


ensembl_gene_id: PMM47T1_08691
symbol: EIK97206.1
gene_biotype: protein_coding
description:
  Arsenical pump membrane protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.


ensembl_gene_id: PMM47T1_08711
symbol: EIK97210.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_08726
symbol: EIK97213.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG3967 Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein).


ensembl_gene_id: PMM47T1_08761
symbol: EIK97220.1
gene_biotype: protein_coding
description:
  Epoxide hydrolase 1; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_08771
symbol: EIK97222.1
gene_biotype: protein_coding
description:
  mutT/nudix family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: PMM47T1_08781
symbol: EIK97224.1
gene_biotype: protein_coding
description:
  DME family transporter ydeD; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: PMM47T1_08821
symbol: EIK97232.1
gene_biotype: protein_coding
description:
  2,5-diketo-D-gluconic acid reductase; COG0656 Aldo/keto reductases, related to diketogulonate reductase.


ensembl_gene_id: PMM47T1_08876
symbol: EIK97243.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase core; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: PMM47T1_08891
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: PMM47T1_08921
symbol: EIK97252.1
gene_biotype: protein_coding
description:
  Putative ABC transport membrane protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: PMM47T1_08926
symbol: EIK97253.1
gene_biotype: protein_coding
description:
  ABC transporter ATPase; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA.


ensembl_gene_id: PMM47T1_08961
symbol: EIK97260.1
gene_biotype: protein_coding
description:
  Crp/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: PMM47T1_08966
symbol: EIK97261.1
gene_biotype: protein_coding
description:
  Hemerythrin hhe cation binding domain-containing protein; COG2846 Regulator of cell morphogenesis and NO signaling.


ensembl_gene_id: PMM47T1_09036
symbol: EIK96791.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter permease; COG4215 ABC-type arginine transport system, permease component.


ensembl_gene_id: PMM47T1_09071
symbol: EIK96798.1
gene_biotype: protein_coding
description:
  Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: PMM47T1_09096
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: PMM47T1_09106
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.


ensembl_gene_id: PMM47T1_09111
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: PMM47T1_09146
symbol: EIK96813.1
gene_biotype: protein_coding
description:
  Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: PMM47T1_09151
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: PMM47T1_09156
symbol: trmL
gene_biotype: protein_coding
description:
  RNA-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: PMM47T1_09166
symbol: ntrC
gene_biotype: protein_coding
description:
  Protein NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: PMM47T1_09196
symbol: thiI
gene_biotype: protein_coding
description:
  tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: PMM47T1_09211
symbol: EIK96826.1
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: PMM47T1_09241
symbol: EIK96832.1
gene_biotype: protein_coding
description:
  Lipoprotein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: PMM47T1_09246
symbol: EIK96833.1
gene_biotype: protein_coding
description:
  N-formimino-L-glutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: PMM47T1_09266
symbol: EIK96837.1
gene_biotype: protein_coding
description:
  Family 3 extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_09271
symbol: EIK96838.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter inner membrane protein; COG4215 ABC-type arginine transport system, permease component.


ensembl_gene_id: PMM47T1_09276
symbol: EIK96839.1
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG4160 ABC-type arginine/histidine transport system, permease component.


ensembl_gene_id: PMM47T1_09286
symbol: EIK96841.1
gene_biotype: protein_coding
description:
  Cytosine/purines uracil thiamine allantoin permease; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: PMM47T1_09291
symbol: EIK96842.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: PMM47T1_09296
symbol: EIK96843.1
gene_biotype: protein_coding
description:
  Histidine ABC transporter ATP-binding protein; COG4175 ABC-type proline/glycine betaine transport system, ATPase component.


ensembl_gene_id: PMM47T1_09316
symbol: EIK96847.1
gene_biotype: protein_coding
description:
  Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: PMM47T1_09321
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: PMM47T1_09326
symbol: mdoG
gene_biotype: protein_coding
description:
  Glucan biosynthesis protein G; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: PMM47T1_09341
symbol: EIK96852.1
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: PMM47T1_09346
symbol: EIK96853.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: PMM47T1_09381
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: PMM47T1_09386
symbol: tatB
gene_biotype: protein_coding
description:
  Twin-arginine translocation system, TatB protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: PMM47T1_09391
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: PMM47T1_09401
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: PMM47T1_09406
symbol: ubiB
gene_biotype: protein_coding
description:
  Putative ubiquinone biosynthesis-like protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.


ensembl_gene_id: PMM47T1_09416
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: PMM47T1_09451
symbol: EIK96874.1
gene_biotype: protein_coding
description:
  Poly(3-hydroxyalkanoate) depolymerase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_09466
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: PMM47T1_09471
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: PMM47T1_09486
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: PMM47T1_09531
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: PMM47T1_09536
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: PMM47T1_09541
symbol: EIK96892.1
gene_biotype: protein_coding
description:
  Sporulation and cell division repeat protein; COG3267 Type II secretory pathway, component ExeA (predicted ATPase).


ensembl_gene_id: PMM47T1_09556
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: PMM47T1_09596
symbol: EIK96903.1
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: PMM47T1_09601
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_09641
symbol: EIK96912.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: PMM47T1_09696
symbol: EIK96923.1
gene_biotype: protein_coding
description:
  CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein; COG1192 ATPases involved in chromosome partitioning.


ensembl_gene_id: PMM47T1_09706
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: PMM47T1_09716
symbol: nhaP2
gene_biotype: protein_coding
description:
  Potassium/proton antiporter; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.


ensembl_gene_id: PMM47T1_09726
symbol: putA
gene_biotype: protein_coding
description:
  Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PMM47T1_09731
symbol: EIK96930.1
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PMM47T1_09741
symbol: msrA-2
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: PMM47T1_09761
symbol: aceF
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase dihydrolipoyltransacetylase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PMM47T1_09766
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PMM47T1_09771
symbol: glnE
gene_biotype: protein_coding
description:
  Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]


ensembl_gene_id: PMM47T1_09791
symbol: EIK96942.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide core heptose(I) kinase RfaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.


ensembl_gene_id: PMM47T1_09811
symbol: EIK96946.1
gene_biotype: protein_coding
description:
  Putative TonB-dependent exported protein; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: PMM47T1_09851
symbol: EIK96954.1
gene_biotype: protein_coding
description:
  O-antigen polymerase/toluene tolerance protein; COG3307 Lipid A core - O-antigen ligase and related enzymes.


ensembl_gene_id: PMM47T1_09856
symbol: msbA
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein/permease; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: PMM47T1_09861
symbol: hldE
gene_biotype: protein_coding
description:
  Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: PMM47T1_09906
symbol: EIK96965.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: PMM47T1_09916
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: PMM47T1_09931
symbol: nudF
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase NudF; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: PMM47T1_09941
symbol: cpdA
gene_biotype: protein_coding
description:
  3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: PMM47T1_09951
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: PMM47T1_09966
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: PMM47T1_09995
symbol: EIK96596.1
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; COG0620 Methionine synthase II (cobalamin-independent).


ensembl_gene_id: PMM47T1_10055
symbol: EIK96608.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, HTH domain/cupin domain-containing protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: PMM47T1_10075
symbol: EIK96612.1
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase superfamily protein; COG1064 Zn-dependent alcohol dehydrogenases.


ensembl_gene_id: PMM47T1_10080
symbol: EIK96613.1
gene_biotype: protein_coding
description:
  Flavin reductase-like domain-containing protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: PMM47T1_10095
symbol: EIK96616.1
gene_biotype: protein_coding
description:
  COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PMM47T1_10175
symbol: rhmD
gene_biotype: protein_coding
description:
  L-rhamnonate dehydratase; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR).


ensembl_gene_id: PMM47T1_10205
symbol: EIK96638.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_10225
symbol: EIK96642.1
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: PMM47T1_10235
symbol: EIK96644.1
gene_biotype: protein_coding
description:
  Multidrug resistance protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_10310
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: PMM47T1_10360
symbol: EIK96669.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_10365
symbol: EIK96670.1
gene_biotype: protein_coding
description:
  5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_10380
symbol: EIK96673.1
gene_biotype: protein_coding
description:
  NAD-binding 6-phosphogluconate dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: PMM47T1_10400
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: PMM47T1_10405
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: PMM47T1_10430
symbol: EIK96683.1
gene_biotype: protein_coding
description:
  Phosphonoacetaldehyde phosphonohydrolase-related protein; COG0637 Predicted phosphatase/phosphohexomutase.


ensembl_gene_id: PMM47T1_10440
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: PMM47T1_10445
symbol: EIK96686.1
gene_biotype: protein_coding
description:
  LolC/E family lipoprotein releasing system, transmembrane protein; COG4591 ABC-type transport system, involved in lipoprotein release, permease component.


ensembl_gene_id: PMM47T1_10450
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein transporter ATP-binding subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: PMM47T1_10470
symbol: sthA
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: PMM47T1_10475
symbol: EIK96692.1
gene_biotype: protein_coding
description:
  ApbE domain-containing protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: PMM47T1_10490
symbol: EIK96695.1
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: PMM47T1_10495
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PMM47T1_10505
symbol: EIK96698.1
gene_biotype: protein_coding
description:
  5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.


ensembl_gene_id: PMM47T1_10510
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: PMM47T1_10520
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: PMM47T1_10525
symbol: EIK96702.1
gene_biotype: protein_coding
description:
  Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: PMM47T1_10540
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...]


ensembl_gene_id: PMM47T1_10550
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: PMM47T1_10555
symbol: fadB
gene_biotype: protein_coding
description:
  Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PMM47T1_10575
symbol: EIK96712.1
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: PMM47T1_10605
symbol: EIK96718.1
gene_biotype: protein_coding
description:
  Lipid kinase; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.


ensembl_gene_id: PMM47T1_10615
symbol: EIK96720.1
gene_biotype: protein_coding
description:
  COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: PMM47T1_10670
symbol: EIK96731.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: PMM47T1_10675
symbol: EIK96732.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: PMM47T1_10680
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: PMM47T1_10770
symbol: EIK96751.1
gene_biotype: protein_coding
description:
  Putative two-component system sensor kinase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_10795
symbol: rlmL
gene_biotype: protein_coding
description:
  23S rRNA m(2)G2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: PMM47T1_10800
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor-like protein; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: PMM47T1_10805
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: PMM47T1_10830
symbol: EIK96763.1
gene_biotype: protein_coding
description:
  Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: PMM47T1_10840
symbol: EIK96765.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: PMM47T1_10845
symbol: EIK96766.1
gene_biotype: protein_coding
description:
  PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: PMM47T1_10875
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: PMM47T1_10900
symbol: EIK96777.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: PMM47T1_10922
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: PMM47T1_10952
symbol: rsgA
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: PMM47T1_10957
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: PMM47T1_10962
symbol: queG
gene_biotype: protein_coding
description:
  Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: PMM47T1_10967
symbol: nnrE
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: PMM47T1_10982
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: PMM47T1_10987
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: PMM47T1_10992
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: PMM47T1_10997
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: PMM47T1_11012
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: PMM47T1_11017
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: PMM47T1_11027
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: PMM47T1_11042
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: PMM47T1_11057
symbol: EIK96461.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: PMM47T1_11087
symbol: EIK96467.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: PMM47T1_11107
symbol: EIK96471.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PMM47T1_11112
symbol: EIK96472.1
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PMM47T1_11122
symbol: EIK96474.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_11127
symbol: EIK96475.1
gene_biotype: protein_coding
description:
  Serine 3-dehydrogenase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_11147
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: PMM47T1_11152
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: PMM47T1_11157
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: PMM47T1_11187
symbol: EIK96487.1
gene_biotype: protein_coding
description:
  Triacylglycerol lipase; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: PMM47T1_11212
symbol: cbpA
gene_biotype: protein_coding
description:
  Chaperone DnaJ domain-containing protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.


ensembl_gene_id: PMM47T1_11227
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: PMM47T1_11242
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: PMM47T1_11247
symbol: ureD
gene_biotype: protein_coding
description:
  Putative uerase accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: PMM47T1_11252
symbol: EIK96500.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: PMM47T1_11257
symbol: EIK96501.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter ATP-binding protein; COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: PMM47T1_11272
symbol: EIK96504.1
gene_biotype: protein_coding
description:
  Putative amino acid ABC transporter substrate-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: PMM47T1_11307
symbol: cbiD
gene_biotype: protein_coding
description:
  cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: PMM47T1_11327
symbol: EIK96515.1
gene_biotype: protein_coding
description:
  Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.


ensembl_gene_id: PMM47T1_11367
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: PMM47T1_11372
symbol: fis
gene_biotype: protein_coding
description:
  Global DNA-binding transcriptional dual regulator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: PMM47T1_11377
symbol: dusB
gene_biotype: protein_coding
description:
  NifR3 family TIM-barrel protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: PMM47T1_11387
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: PMM47T1_11392
symbol: EIK96528.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PMM47T1_11397
symbol: EIK96529.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PMM47T1_11402
symbol: dipZ
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein precursor; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: PMM47T1_11417
symbol: EIK96533.1
gene_biotype: protein_coding
description:
  mutT/nudix family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: PMM47T1_11462
symbol: EIK96542.1
gene_biotype: protein_coding
description:
  Type II and III secretion system protein; COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: PMM47T1_11532
symbol: cmoM
gene_biotype: protein_coding
description:
  smtA protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: PMM47T1_11612
symbol: EIK96572.1
gene_biotype: protein_coding
description:
  Bcr/CflA family drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_11622
symbol: EIK96574.1
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase superfamily protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: PMM47T1_11642
symbol: EIK96578.1
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: PMM47T1_11647
symbol: EIK96579.1
gene_biotype: protein_coding
description:
  2OG-Fe(II) oxygenase; COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: PMM47T1_11652
symbol: EIK96580.1
gene_biotype: protein_coding
description:
  Bmp family lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: PMM47T1_11662
symbol: EIK96582.1
gene_biotype: protein_coding
description:
  Hydroxydechloroatrazine ethylaminohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: PMM47T1_11672
symbol: EIK96584.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PMM47T1_11677
symbol: EIK96585.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PMM47T1_11707
symbol: EIK96591.1
gene_biotype: protein_coding
description:
  Beta alanine--pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PMM47T1_11786
symbol: EIK96288.1
gene_biotype: protein_coding
description:
  Anti-sigma-factor antagonist (STAS); COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).


ensembl_gene_id: PMM47T1_11796
symbol: EIK96290.1
gene_biotype: protein_coding
description:
  Putative mechanosensitive ion channel family protein; COG0668 Small-conductance mechanosensitive channel.


ensembl_gene_id: PMM47T1_11861
symbol: aroE-2
gene_biotype: protein_coding
description:
  Shikimate/quinate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: PMM47T1_11876
symbol: EIK96306.1
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.


ensembl_gene_id: PMM47T1_11891
symbol: EIK96309.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_11896
symbol: EIK96310.1
gene_biotype: protein_coding
description:
  Putative oligopeptide ABC transporter membrane protein; COG4239 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: PMM47T1_11901
symbol: EIK96311.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG4174 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: PMM47T1_11906
symbol: EIK96312.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component; overlaps another CDS with the same product name.


ensembl_gene_id: PMM47T1_11926
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: PMM47T1_11941
symbol: EIK96319.1
gene_biotype: protein_coding
description:
  Aminotransferase class i and ii; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.


ensembl_gene_id: PMM47T1_11946
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: PMM47T1_11976
symbol: phnX
gene_biotype: protein_coding
description:
  Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.


ensembl_gene_id: PMM47T1_11981
symbol: phnW
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.


ensembl_gene_id: PMM47T1_12036
symbol: EIK96338.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma-70 factor, ECF subfamily, PrtI; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PMM47T1_12076
symbol: EIK96346.1
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PMM47T1_12196
symbol: EIK96370.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter substrate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: PMM47T1_12201
symbol: EIK96371.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PMM47T1_12246
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: PMM47T1_12256
symbol: EIK96382.1
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: PMM47T1_12261
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: PMM47T1_12266
symbol: EIK96384.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PMM47T1_12271
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PMM47T1_12276
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: PMM47T1_12281
symbol: EIK96387.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: PMM47T1_12286
symbol: EIK96388.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: PMM47T1_12296
symbol: nuoC
gene_biotype: protein_coding
description:
  Bifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: PMM47T1_12301
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PMM47T1_12306
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: PMM47T1_12316
symbol: EIK96394.1
gene_biotype: protein_coding
description:
  Type II/III secretion system short domain-containing protein; COG1450 Type II secretory pathway, component PulD.


ensembl_gene_id: PMM47T1_12341
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: PMM47T1_12346
symbol: nudJ
gene_biotype: protein_coding
description:
  NUDIX family hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: PMM47T1_12366
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: PMM47T1_12371
symbol: EIK96405.1
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PMM47T1_12376
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: PMM47T1_12381
symbol: bpt
gene_biotype: protein_coding
description:
  arginyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: PMM47T1_12386
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: PMM47T1_12396
symbol: lolA
gene_biotype: protein_coding
description:
  Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: PMM47T1_12401
symbol: EIK96411.1
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: PMM47T1_12406
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: PMM47T1_12411
symbol: cysG
gene_biotype: protein_coding
description:
  Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: PMM47T1_12436
symbol: EIK96418.1
gene_biotype: protein_coding
description:
  Sulfur relay protein TusB/DsrH; COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur.


ensembl_gene_id: PMM47T1_12441
symbol: EIK96419.1
gene_biotype: protein_coding
description:
  Sulfur relay protein TusC; COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur; Belongs to the DsrF/TusC family.


ensembl_gene_id: PMM47T1_12446
symbol: EIK96420.1
gene_biotype: protein_coding
description:
  Sulfur transfer complex subunit TusD; COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction.


ensembl_gene_id: PMM47T1_12486
symbol: EIK96426.1
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_12523
symbol: EIK96115.1
gene_biotype: protein_coding
description:
  Protein secretion ABC efflux system, permease and ATP-binding protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: PMM47T1_12533
symbol: EIK96117.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: PMM47T1_12543
symbol: EIK96119.1
gene_biotype: protein_coding
description:
  Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.


ensembl_gene_id: PMM47T1_12598
symbol: EIK96130.1
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthsis glycosyltransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: PMM47T1_12658
symbol: EIK96142.1
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosidase II; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.


ensembl_gene_id: PMM47T1_12678
symbol: EIK96146.1
gene_biotype: protein_coding
description:
  Mandelate racemase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: PMM47T1_12703
symbol: EIK96151.1
gene_biotype: protein_coding
description:
  Putative glucose dehydrogenase subunit alpha; COG2303 Choline dehydrogenase and related flavoproteins.


ensembl_gene_id: PMM47T1_12713
symbol: EIK96153.1
gene_biotype: protein_coding
description:
  COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: PMM47T1_12758
symbol: EIK96162.1
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: PMM47T1_12858
symbol: EIK96182.1
gene_biotype: protein_coding
description:
  Permease, cytosine/purine, uracil, thiamine, allantoin family protein; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: PMM47T1_12868
symbol: EIK96184.1
gene_biotype: protein_coding
description:
  Sulfonate/nitrate transport system substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_12883
symbol: EIK96187.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: PMM47T1_12943
symbol: EIK96199.1
gene_biotype: protein_coding
description:
  Inositol transport system sugar-binding protein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: PMM47T1_12963
symbol: EIK96203.1
gene_biotype: protein_coding
description:
  Sugar transporter family protein; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: PMM47T1_12983
symbol: EIK96207.1
gene_biotype: protein_coding
description:
  Histidine kinase, HAMP region: chemotaxis sensory transducer; COG0840 Methyl-accepting chemotaxis protein.


ensembl_gene_id: PMM47T1_13003
symbol: EIK96211.1
gene_biotype: protein_coding
description:
  Spermidine/putrescine transport system substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: PMM47T1_13008
symbol: aguA
gene_biotype: protein_coding
description:
  Peptidyl-arginine deiminase; Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.


ensembl_gene_id: PMM47T1_13023
symbol: EIK96215.1
gene_biotype: protein_coding
description:
  FAD-binding monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_13048
symbol: EIK96220.1
gene_biotype: protein_coding
description:
  Cyn operon transcriptional activator; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PMM47T1_13078
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: PMM47T1_13083
symbol: EIK96227.1
gene_biotype: protein_coding
description:
  NtaA/SnaA/SoxA family monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_13088
symbol: EIK96228.1
gene_biotype: protein_coding
description:
  Aliphatic sulfonate ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_13138
symbol: EIK96238.1
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_13143
symbol: EIK96239.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_13163
symbol: EIK96243.1
gene_biotype: protein_coding
description:
  Glutathione-independent formaldehyde dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: PMM47T1_13168
symbol: EIK96244.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: PMM47T1_13183
symbol: folD
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: PMM47T1_13188
symbol: EIK96248.1
gene_biotype: protein_coding
description:
  Nitrilotriacetate monooxygenase component A; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_13218
symbol: EIK96254.1
gene_biotype: protein_coding
description:
  ABC transporter sulfate ester binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_13223
symbol: EIK96255.1
gene_biotype: protein_coding
description:
  exo-poly-alpha-D-galacturonosidase; COG5434 Endopolygalacturonase; Belongs to the glycosyl hydrolase 28 family.


ensembl_gene_id: PMM47T1_13283
symbol: EIK96267.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3376 High-affinity nickel permease; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: PMM47T1_13355
symbol: EIK95949.1
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_13370
symbol: EIK95952.1
gene_biotype: protein_coding
description:
  Putative 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PMM47T1_13405
symbol: EIK95959.1
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: PMM47T1_13460
symbol: EIK95970.1
gene_biotype: protein_coding
description:
  Ferric siderophore ABC transporter substrate-binding protein; COG0810 Periplasmic protein TonB, links inner and outer membranes.


ensembl_gene_id: PMM47T1_13480
symbol: EIK95974.1
gene_biotype: protein_coding
description:
  Solute-binding family 5 protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: PMM47T1_13495
symbol: EIK95977.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_13510
symbol: EIK95980.1
gene_biotype: protein_coding
description:
  2-pyrone-4,6-dicarboxylate lactonase; COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: PMM47T1_13540
symbol: EIK95986.1
gene_biotype: protein_coding
description:
  P-hydroxycinnamoyl CoA hydratase/lyase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PMM47T1_13545
symbol: EIK95987.1
gene_biotype: protein_coding
description:
  Putative 3-hydroxyphenylpropionic transporter MhpT; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_13560
symbol: EIK95990.1
gene_biotype: protein_coding
description:
  LuxR family DNA-binding response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PMM47T1_13605
symbol: EIK95999.1
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: PMM47T1_13645
symbol: EIK96007.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PMM47T1_13650
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: PMM47T1_13690
symbol: EIK96016.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: PMM47T1_13700
symbol: EIK96018.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG4239 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: PMM47T1_14165
symbol: azoR
gene_biotype: protein_coding
description:
  Azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: PMM47T1_14186
symbol: EIK95813.1
gene_biotype: protein_coding
description:
  Pseudaminic acid biosynthesis N-acetyl transferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: PMM47T1_14301
symbol: EIK95836.1
gene_biotype: protein_coding
description:
  Rhamnosyltransferase chain A; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_14306
symbol: EIK95837.1
gene_biotype: protein_coding
description:
  Rhamnosyltransferase chain B; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: PMM47T1_14321
symbol: EIK95840.1
gene_biotype: protein_coding
description:
  Monooxygenase flavin-binding family protein; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: PMM47T1_14326
symbol: EIK95841.1
gene_biotype: protein_coding
description:
  Glycosyltransferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: PMM47T1_14356
symbol: EIK95847.1
gene_biotype: protein_coding
description:
  Putative multidrug resistance protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_14386
symbol: EIK95853.1
gene_biotype: protein_coding
description:
  Dolichyl-phosphate-mannose-protein mannosyltransferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: PMM47T1_14406
symbol: arnF
gene_biotype: protein_coding
description:
  4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: PMM47T1_14411
symbol: arnE
gene_biotype: protein_coding
description:
  Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.


ensembl_gene_id: PMM47T1_14421
symbol: arnD
gene_biotype: protein_coding
description:
  4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase ArnD; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: PMM47T1_14426
symbol: arnA
gene_biotype: protein_coding
description:
  Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily.


ensembl_gene_id: PMM47T1_14431
symbol: arnC
gene_biotype: protein_coding
description:
  UDP-phosphate 4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: PMM47T1_14436
symbol: arnB
gene_biotype: protein_coding
description:
  UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: PMM47T1_14461
symbol: tpx
gene_biotype: protein_coding
description:
  Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: PMM47T1_14466
symbol: EIK95869.1
gene_biotype: protein_coding
description:
  Multidrug ABC transporter permease; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_14471
symbol: EIK95870.1
gene_biotype: protein_coding
description:
  Multidrug RND efflux transporter permease MdtB; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_14486
symbol: EIK95873.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG3300 MHYT domain (predicted integral membrane sensor domain).


ensembl_gene_id: PMM47T1_14491
symbol: EIK95874.1
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_14501
symbol: EIK95876.1
gene_biotype: protein_coding
description:
  GAF sensor-containing diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: PMM47T1_14536
symbol: glgE
gene_biotype: protein_coding
description:
  Alpha amylase, catalytic region; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: PMM47T1_14546
symbol: glgB
gene_biotype: protein_coding
description:
  Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: PMM47T1_14576
symbol: EIK95891.1
gene_biotype: protein_coding
description:
  Glycogen debranching protein GlgX; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: PMM47T1_14606
symbol: EIK95897.1
gene_biotype: protein_coding
description:
  Calcium/calmodulin dependent protein kinase II association-domain-containing protein; COG4875 Uncharacterized protein conserved in bacteria with a cystatin-like fold.


ensembl_gene_id: PMM47T1_14641
symbol: nudC
gene_biotype: protein_coding
description:
  NADH pyrophosphatase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. NudC subfamily.


ensembl_gene_id: PMM47T1_14671
symbol: EIK95910.1
gene_biotype: protein_coding
description:
  Heme-containing peroxidase/deferrochelatase EfeB; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: PMM47T1_14731
symbol: metH
gene_biotype: protein_coding
description:
  B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: PMM47T1_14746
symbol: nfuA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: PMM47T1_14771
symbol: cobN
gene_biotype: protein_coding
description:
  Cobaltochelatase subunit CobN; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: PMM47T1_14831
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: PMM47T1_14846
symbol: EIK95673.1
gene_biotype: protein_coding
description:
  Short-chain alcohol dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_14861
symbol: EIK95676.1
gene_biotype: protein_coding
description:
  BNR repeat-containing protein; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: PMM47T1_14876
symbol: EIK95679.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_14881
symbol: EIK95680.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_14886
symbol: EIK95681.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster-binding protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: PMM47T1_14916
symbol: EIK95687.1
gene_biotype: protein_coding
description:
  Putative alkanesulfonate monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_14921
symbol: EIK95688.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily.


ensembl_gene_id: PMM47T1_14936
symbol: selA
gene_biotype: protein_coding
description:
  Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: PMM47T1_14981
symbol: map-2
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: PMM47T1_15026
symbol: EIK95709.1
gene_biotype: protein_coding
description:
  Permidine/putrescine ABC transporter inner membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: PMM47T1_15046
symbol: EIK95713.1
gene_biotype: protein_coding
description:
  Putative lipoprotein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: PMM47T1_15131
symbol: EIK95730.1
gene_biotype: protein_coding
description:
  LuxR family DNA-binding response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_15141
symbol: benD
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_15146
symbol: EIK95733.1
gene_biotype: protein_coding
description:
  Toluate 1,2-dioxygenase electron transfer component; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: PMM47T1_15156
symbol: EIK95735.1
gene_biotype: protein_coding
description:
  Toluate 1,2-dioxygenase subunit alpha; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_15176
symbol: EIK95739.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_15221
symbol: bamA-2
gene_biotype: protein_coding
description:
  Surface antigen protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PMM47T1_15231
symbol: EIK95750.1
gene_biotype: protein_coding
description:
  2-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PMM47T1_15276
symbol: EIK95759.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: PMM47T1_15281
symbol: EIK95760.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: PMM47T1_15291
symbol: EIK95762.1
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase family oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_15331
symbol: EIK95766.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_15336
symbol: EIK95767.1
gene_biotype: protein_coding
description:
  Putative fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_15386
symbol: EIK95774.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: PMM47T1_15416
symbol: EIK95780.1
gene_biotype: protein_coding
description:
  Putative AMP-dependent synthetase and ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: PMM47T1_15436
symbol: EIK95784.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_15486
symbol: EIK95794.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: PMM47T1_15501
symbol: EIK95797.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_15633
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: PMM47T1_15643
symbol: htpX
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: PMM47T1_15648
symbol: tpm
gene_biotype: protein_coding
description:
  Thiopurine S-methyltransferase; COG0500 SAM-dependent methyltransferases; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: PMM47T1_15658
symbol: deaD
gene_biotype: protein_coding
description:
  Cold-shock DEAD box protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: PMM47T1_15673
symbol: EIK95539.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.


ensembl_gene_id: PMM47T1_15698
symbol: EIK95544.1
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: PMM47T1_15703
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: PMM47T1_15803
symbol: EIK95565.1
gene_biotype: protein_coding
description:
  COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: PMM47T1_15853
symbol: EIK95575.1
gene_biotype: protein_coding
description:
  Putative sulfatase; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.


ensembl_gene_id: PMM47T1_15878
symbol: mtnC
gene_biotype: protein_coding
description:
  HAD-superfamily hydrolase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: PMM47T1_15883
symbol: mtnD
gene_biotype: protein_coding
description:
  Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: PMM47T1_15888
symbol: mtnB
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: PMM47T1_15893
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: PMM47T1_15908
symbol: prmB
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: PMM47T1_15978
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: PMM47T1_16018
symbol: EIK95608.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: PMM47T1_16038
symbol: EIK95612.1
gene_biotype: protein_coding
description:
  COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: PMM47T1_16048
symbol: EIK95614.1
gene_biotype: protein_coding
description:
  Helix-hairpin-helix repeat-containing competence protein ComEA; COG1555 DNA uptake protein and related DNA-binding proteins.


ensembl_gene_id: PMM47T1_16053
symbol: EIK95615.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein CapD; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: PMM47T1_16058
symbol: EIK95616.1
gene_biotype: protein_coding
description:
  Glycosyl transferase family protein; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: PMM47T1_16083
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: PMM47T1_16108
symbol: EIK95626.1
gene_biotype: protein_coding
description:
  CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3- dehydrase reductase; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: PMM47T1_16113
symbol: EIK95627.1
gene_biotype: protein_coding
description:
  Glucose-1-phosphate cytidylyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: PMM47T1_16123
symbol: EIK95629.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein RfbH; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PMM47T1_16128
symbol: EIK95630.1
gene_biotype: protein_coding
description:
  Acetolactate synthase II, large subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: PMM47T1_16173
symbol: EIK95639.1
gene_biotype: protein_coding
description:
  Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: PMM47T1_16183
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: PMM47T1_16198
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: PMM47T1_16208
symbol: aroA-2
gene_biotype: protein_coding
description:
  Bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: PMM47T1_16223
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: PMM47T1_16228
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PMM47T1_16233
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: PMM47T1_16243
symbol: ubiG
gene_biotype: protein_coding
description:
  Bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: PMM47T1_16253
symbol: EIK95655.1
gene_biotype: protein_coding
description:
  Putative oxoacyl-(acyl carrier protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_16268
symbol: EIK95658.1
gene_biotype: protein_coding
description:
  ABC transporter permease/ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: PMM47T1_16278
symbol: EIK95660.1
gene_biotype: protein_coding
description:
  Putative rhodanese-related sulfurtransferase; COG1054 Predicted sulfurtransferase; Belongs to the UPF0176 family.


ensembl_gene_id: PMM47T1_16283
symbol: EIK95661.1
gene_biotype: protein_coding
description:
  BolA-like protein; COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.


ensembl_gene_id: PMM47T1_16293
symbol: fumC-2
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: PMM47T1_16318
symbol: mnmC
gene_biotype: protein_coding
description:
  Bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: PMM47T1_16323
symbol: EIK95669.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: PMM47T1_16355
symbol: EIK95378.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_16385
symbol: EIK95384.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: PMM47T1_16445
symbol: dnaE2
gene_biotype: protein_coding
description:
  Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: PMM47T1_16450
symbol: EIK95397.1
gene_biotype: protein_coding
description:
  Iron(III) dicitrate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_16475
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: PMM47T1_16480
symbol: EIK95403.1
gene_biotype: protein_coding
description:
  Oxidoreductase alpha (molybdopterin) subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PMM47T1_16525
symbol: EIK95412.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PMM47T1_16545
symbol: EIK95416.1
gene_biotype: protein_coding
description:
  Type VI secretion system, Vgr family protein; COG3501 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PMM47T1_16550
symbol: EIK95417.1
gene_biotype: protein_coding
description:
  Chaperone; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PMM47T1_16615
symbol: ddl-2
gene_biotype: protein_coding
description:
  D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: PMM47T1_16660
symbol: EIK95439.1
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal protein; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: PMM47T1_16665
symbol: EIK95440.1
gene_biotype: protein_coding
description:
  Formate dehydrogenase subunit alpha; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PMM47T1_16670
symbol: EIK95441.1
gene_biotype: protein_coding
description:
  Nitrate-inducible formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: PMM47T1_16680
symbol: fdhE
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: PMM47T1_16685
symbol: EIK95444.1
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: PMM47T1_16695
symbol: EIK95446.1
gene_biotype: protein_coding
description:
  Monooxygenase, NtaA/SnaA/SoxA family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_16700
symbol: EIK95447.1
gene_biotype: protein_coding
description:
  Putative alkanesulfonate ABC transporter periplasmic binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_16715
symbol: EIK95450.1
gene_biotype: protein_coding
description:
  Putative monooxygenase protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_16735
symbol: EIK95454.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_16755
symbol: EIK95458.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: PMM47T1_16765
symbol: EIK95460.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: PMM47T1_16780
symbol: EIK95463.1
gene_biotype: protein_coding
description:
  Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: PMM47T1_16790
symbol: EIK95465.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: PMM47T1_16800
symbol: dkgB
gene_biotype: protein_coding
description:
  2,5-diketo-D-gluconate reductase B; COG0656 Aldo/keto reductases, related to diketogulonate reductase.


ensembl_gene_id: PMM47T1_16830
symbol: mntH
gene_biotype: protein_coding
description:
  Mn2+/Fe2+ transporter; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: PMM47T1_16860
symbol: EIK95479.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate transport protein; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PMM47T1_16870
symbol: leuD-2
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: PMM47T1_16875
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: PMM47T1_16895
symbol: EIK95486.1
gene_biotype: protein_coding
description:
  Putative fumarylpyruvate hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_16950
symbol: EIK95497.1
gene_biotype: protein_coding
description:
  PilT domain-containing protein; COG1569 Predicted nucleic acid-binding protein, contains PIN domain.


ensembl_gene_id: PMM47T1_16975
symbol: EIK95499.1
gene_biotype: protein_coding
description:
  COG3588 Fructose-1,6-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.


ensembl_gene_id: PMM47T1_17005
symbol: EIK95505.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG1064 Zn-dependent alcohol dehydrogenases.


ensembl_gene_id: PMM47T1_17025
symbol: EIK95509.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 3; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_17095
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: PMM47T1_17160
symbol: rsmC
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: PMM47T1_17200
symbol: EIK95253.1
gene_biotype: protein_coding
description:
  ompA family protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: PMM47T1_17210
symbol: EIK95255.1
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: PMM47T1_17245
symbol: cysZ
gene_biotype: protein_coding
description:
  Putative sulfate transport protein CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: PMM47T1_17280
symbol: EIK95269.1
gene_biotype: protein_coding
description:
  Dihydromonapterin reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_17305
symbol: EIK95274.1
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_17335
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: PMM47T1_17340
symbol: EIK95281.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_17360
symbol: pdhA
gene_biotype: protein_coding
description:
  TPP-dependent dehydrogenase, E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: PMM47T1_17365
symbol: EIK95286.1
gene_biotype: protein_coding
description:
  Transketolase, central region; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: PMM47T1_17370
symbol: EIK95287.1
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: PMM47T1_17465
symbol: EIK95306.1
gene_biotype: protein_coding
description:
  Secretion protein HlyD family protein; COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_17485
symbol: EIK95310.1
gene_biotype: protein_coding
description:
  Alginate biosynthesis protein AlgA; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: PMM47T1_17500
symbol: EIK95313.1
gene_biotype: protein_coding
description:
  Membrane bound O-acyl transferase, MBOAT; COG1696 Predicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: PMM47T1_17505
symbol: algL
gene_biotype: protein_coding
description:
  poly(beta-D-mannuronate) lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism; Belongs to the polysaccharide lyase 5 family.


ensembl_gene_id: PMM47T1_17540
symbol: EIK95321.1
gene_biotype: protein_coding
description:
  COG1004 Predicted UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: PMM47T1_17555
symbol: EIK95324.1
gene_biotype: protein_coding
description:
  PhoH family protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: PMM47T1_17560
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: PMM47T1_17575
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: PMM47T1_17585
symbol: EIK95330.1
gene_biotype: protein_coding
description:
  General L-amino acid ABC transporter periplasmic L-amino acid-binding protein AapJ; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_17595
symbol: EIK95332.1
gene_biotype: protein_coding
description:
  General L-amino acid ABC transporter permease AapM; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: PMM47T1_17650
symbol: EIK95343.1
gene_biotype: protein_coding
description:
  COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: PMM47T1_17655
symbol: rlmF
gene_biotype: protein_coding
description:
  23S rRNA mA1618 methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA.


ensembl_gene_id: PMM47T1_17660
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: PMM47T1_17675
symbol: pepA
gene_biotype: protein_coding
description:
  Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: PMM47T1_17710
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: PMM47T1_17715
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: PMM47T1_17735
symbol: EIK95360.1
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: PMM47T1_17755
symbol: EIK95364.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: PMM47T1_17775
symbol: EIK95368.1
gene_biotype: protein_coding
description:
  TonB-dependent hemoglobin/transferrin/lactoferrin receptor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: PMM47T1_17785
symbol: EIK95370.1
gene_biotype: protein_coding
description:
  Sigma-24 (FecI); COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PMM47T1_17795
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: PMM47T1_17875
symbol: EIK95100.1
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: PMM47T1_17880
symbol: EIK95101.1
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: PMM47T1_17895
symbol: gatC
gene_biotype: protein_coding
description:
  asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: PMM47T1_17900
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: PMM47T1_17905
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: PMM47T1_17910
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: PMM47T1_17935
symbol: EIK95112.1
gene_biotype: protein_coding
description:
  Hcp1 family type VI secretion system effector; COG3157 Hemolysin-coregulated protein (uncharacterized).


ensembl_gene_id: PMM47T1_17955
symbol: EIK95116.1
gene_biotype: protein_coding
description:
  Putative sugar ABC transporter membrane protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_17960
symbol: EIK95117.1
gene_biotype: protein_coding
description:
  5-dehydro-4-deoxyglucarate dehydratase; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: PMM47T1_17970
symbol: EIK95119.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG4178 ABC-type uncharacterized transport system, permease and ATPase components.


ensembl_gene_id: PMM47T1_17975
symbol: EIK95120.1
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator; COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain.


ensembl_gene_id: PMM47T1_17990
symbol: EIK95123.1
gene_biotype: protein_coding
description:
  Peptide ABC transporter substrate-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: PMM47T1_18000
symbol: EIK95125.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: PMM47T1_18025
symbol: EIK95130.1
gene_biotype: protein_coding
description:
  Protein DppD; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_18030
symbol: dppF
gene_biotype: protein_coding
description:
  Dipeptide transporter ATP-binding subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_18045
symbol: EIK95134.1
gene_biotype: protein_coding
description:
  Polyamine ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: PMM47T1_18050
symbol: EIK95135.1
gene_biotype: protein_coding
description:
  Cat operon regulatory protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PMM47T1_18055
symbol: EIK95136.1
gene_biotype: protein_coding
description:
  Muconate cycloisomerase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: PMM47T1_18070
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: PMM47T1_18085
symbol: EIK95142.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: PMM47T1_18090
symbol: EIK95143.1
gene_biotype: protein_coding
description:
  COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: PMM47T1_18140
symbol: EIK95153.1
gene_biotype: protein_coding
description:
  PTS system fructose-specific transporter subunits IIBC; COG1445 Phosphotransferase system fructose-specific component IIB.


ensembl_gene_id: PMM47T1_18145
symbol: EIK95154.1
gene_biotype: protein_coding
description:
  1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: PMM47T1_18150
symbol: EIK95155.1
gene_biotype: protein_coding
description:
  COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: PMM47T1_18170
symbol: EIK95159.1
gene_biotype: protein_coding
description:
  N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression.


ensembl_gene_id: PMM47T1_18205
symbol: EIK95166.1
gene_biotype: protein_coding
description:
  Fimbrial protein; COG4969 Tfp pilus assembly protein, major pilin PilA; Belongs to the N-Me-Phe pilin family.


ensembl_gene_id: PMM47T1_18210
symbol: EIK95167.1
gene_biotype: protein_coding
description:
  Type 4 fimbrial assembly protein; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: PMM47T1_18220
symbol: EIK95169.1
gene_biotype: protein_coding
description:
  Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: PMM47T1_18225
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: PMM47T1_18230
symbol: yacG
gene_biotype: protein_coding
description:
  DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: PMM47T1_18270
symbol: clpB
gene_biotype: protein_coding
description:
  Chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PMM47T1_18275
symbol: EIK95180.1
gene_biotype: protein_coding
description:
  Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: PMM47T1_18280
symbol: EIK95181.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PMM47T1_18285
symbol: bamD
gene_biotype: protein_coding
description:
  Competence lipoprotein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PMM47T1_18345
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: PMM47T1_18355
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: PMM47T1_18360
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: PMM47T1_18365
symbol: EIK95198.1
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.


ensembl_gene_id: PMM47T1_18370
symbol: murJ
gene_biotype: protein_coding
description:
  Protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: PMM47T1_18390
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: PMM47T1_18395
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: PMM47T1_18405
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: PMM47T1_18410
symbol: EIK95207.1
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PMM47T1_18415
symbol: EIK95208.1
gene_biotype: protein_coding
description:
  Alkylphosphonate utilization protein PhnA; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: PMM47T1_18470
symbol: EIK95219.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: PMM47T1_18500
symbol: EIK95225.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: PMM47T1_18540
symbol: ppnK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: PMM47T1_18615
symbol: EIK94994.1
gene_biotype: protein_coding
description:
  Periplasmic multidrug efflux lipoprotein precursor; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_18625
symbol: EIK94996.1
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: PMM47T1_18645
symbol: EIK95000.1
gene_biotype: protein_coding
description:
  2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: PMM47T1_18715
symbol: allA
gene_biotype: protein_coding
description:
  Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.


ensembl_gene_id: PMM47T1_18735
symbol: EIK95018.1
gene_biotype: protein_coding
description:
  Hydroxyisourate hydrolase; COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: PMM47T1_18760
symbol: EIK95023.1
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: PMM47T1_18785
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: PMM47T1_18790
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: PMM47T1_18795
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: PMM47T1_18810
symbol: EIK95033.1
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: PMM47T1_18895
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: PMM47T1_18900
symbol: EIK95051.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: PMM47T1_18910
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: PMM47T1_18915
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: PMM47T1_18920
symbol: EIK95055.1
gene_biotype: protein_coding
description:
  Transcriptional regulator Anr; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: PMM47T1_18930
symbol: EIK95057.1
gene_biotype: protein_coding
description:
  COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: PMM47T1_18940
symbol: EIK95059.1
gene_biotype: protein_coding
description:
  Cytochrome oxidase maturation protein cbb3-type; COG3197 Uncharacterized protein, possibly involved in nitrogen fixation.


ensembl_gene_id: PMM47T1_18960
symbol: EIK95063.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase cbb3-type subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: PMM47T1_18975
symbol: EIK95066.1
gene_biotype: protein_coding
description:
  COG3278 Cbb3-type cytochrome oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: PMM47T1_19000
symbol: rlmM
gene_biotype: protein_coding
description:
  Putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: PMM47T1_19005
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfur transfer protein SirA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: PMM47T1_19025
symbol: EIK95076.1
gene_biotype: protein_coding
description:
  Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: PMM47T1_19065
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PMM47T1_19070
symbol: EIK95085.1
gene_biotype: protein_coding
description:
  Protein PpiB; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: PMM47T1_19090
symbol: folD-2
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: PMM47T1_19166
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: PMM47T1_19181
symbol: EIK94873.1
gene_biotype: protein_coding
description:
  Von Willebrand factor A; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.


ensembl_gene_id: PMM47T1_19226
symbol: EIK94882.1
gene_biotype: protein_coding
description:
  Transglutaminase-like domain protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: PMM47T1_19256
symbol: EIK94888.1
gene_biotype: protein_coding
description:
  Putative transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: PMM47T1_19296
symbol: EIK94896.1
gene_biotype: protein_coding
description:
  OmpR family DNA-binding response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_19301
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: PMM47T1_19306
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: PMM47T1_19311
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: PMM47T1_19331
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: PMM47T1_19346
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: PMM47T1_19366
symbol: EIK94910.1
gene_biotype: protein_coding
description:
  Siderophore biosynthesis protein; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: PMM47T1_19371
symbol: EIK94911.1
gene_biotype: protein_coding
description:
  Extracytoplasmic-function sigma-70 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: PMM47T1_19406
symbol: EIK94918.1
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: PMM47T1_19426
symbol: EIK94922.1
gene_biotype: protein_coding
description:
  Galactonate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: PMM47T1_19456
symbol: argC-2
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: PMM47T1_19471
symbol: EIK94931.1
gene_biotype: protein_coding
description:
  Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: PMM47T1_19496
symbol: EIK94936.1
gene_biotype: protein_coding
description:
  OmpA family protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: PMM47T1_19531
symbol: EIK94943.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: PMM47T1_19536
symbol: sdhA
gene_biotype: protein_coding
description:
  COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: PMM47T1_19551
symbol: EIK94947.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: PMM47T1_19556
symbol: EIK94948.1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: PMM47T1_19561
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: PMM47T1_19566
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: PMM47T1_19576
symbol: EIK94952.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: PMM47T1_19626
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-(acyl carrier protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: PMM47T1_19636
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PMM47T1_19651
symbol: EIK94967.1
gene_biotype: protein_coding
description:
  Putative thioesterase; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: PMM47T1_19661
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: PMM47T1_19666
symbol: EIK94970.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component.


ensembl_gene_id: PMM47T1_19671
symbol: EIK94971.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: PMM47T1_19703
symbol: EIK94757.1
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation operon negative regulatory protein PaaX; COG3327 Phenylacetic acid-responsive transcriptional repressor.


ensembl_gene_id: PMM47T1_19708
symbol: EIK94758.1
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation protein PaaY; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.


ensembl_gene_id: PMM47T1_19713
symbol: EIK94759.1
gene_biotype: protein_coding
description:
  Quinohemoprotein alcohol dehydrogenase; COG4313 Protein involved in meta-pathway of phenol degradation.


ensembl_gene_id: PMM47T1_19718
symbol: EIK94760.1
gene_biotype: protein_coding
description:
  DNA-binding transcriptional activator FeaR; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: PMM47T1_19758
symbol: EIK94768.1
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation protein PaaD; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: PMM47T1_19773
symbol: EIK94769.1
gene_biotype: protein_coding
description:
  phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: PMM47T1_19783
symbol: paaB
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase subunit PaaB; COG3460 Uncharacterized enzyme of phenylacetate metabolism.


ensembl_gene_id: PMM47T1_19793
symbol: EIK94773.1
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase subunit PaaJ; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.


ensembl_gene_id: PMM47T1_19798
symbol: EIK94774.1
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase subunit PaaK; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: PMM47T1_19803
symbol: EIK94775.1
gene_biotype: protein_coding
description:
  Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases.


ensembl_gene_id: PMM47T1_19823
symbol: EIK94779.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain.


ensembl_gene_id: PMM47T1_19833
symbol: EIK94781.1
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase superfamily protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: PMM47T1_19898
symbol: EIK94794.1
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase, iron-sulfur binding subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: PMM47T1_19928
symbol: EIK94800.1
gene_biotype: protein_coding
description:
  Vanillate monooxygenase; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_19973
symbol: gudD
gene_biotype: protein_coding
description:
  Glucarate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: PMM47T1_19978
symbol: mrdA
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: PMM47T1_20008
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: PMM47T1_20038
symbol: EIK94822.1
gene_biotype: protein_coding
description:
  Cation/multidrug efflux transport protein AcrB; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_20043
symbol: EIK94823.1
gene_biotype: protein_coding
description:
  RND family Efflux transporter MFP Subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PMM47T1_20073
symbol: EIK94829.1
gene_biotype: protein_coding
description:
  OprD regulatory protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PMM47T1_20093
symbol: EIK94833.1
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-2 family protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: PMM47T1_20113
symbol: EIK94837.1
gene_biotype: protein_coding
description:
  TonB-dependent outermembrane receptor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: PMM47T1_20128
symbol: EIK94840.1
gene_biotype: protein_coding
description:
  Fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_20218
symbol: EIK94658.1
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: PMM47T1_20233
symbol: EIK94661.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_20243
symbol: EIK94663.1
gene_biotype: protein_coding
description:
  COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: PMM47T1_20248
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: PMM47T1_20253
symbol: EIK94665.1
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate regulon repressor, DeoR family protein; COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: PMM47T1_20258
symbol: glpD
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PMM47T1_20278
symbol: EIK94670.1
gene_biotype: protein_coding
description:
  Glutamate/aspartate ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: PMM47T1_20303
symbol: EIK94675.1
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthio-1-phosphopentane phosphatase; COG4359 Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling.


ensembl_gene_id: PMM47T1_20308
symbol: EIK94676.1
gene_biotype: protein_coding
description:
  Class III aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PMM47T1_20333
symbol: EIK94681.1
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: PMM47T1_20393
symbol: EIK94693.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase-like protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: PMM47T1_20438
symbol: EIK94702.1
gene_biotype: protein_coding
description:
  Carboxylate/amino acid/amine transporter; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: PMM47T1_20443
symbol: azoR-2
gene_biotype: protein_coding
description:
  FMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: PMM47T1_20463
symbol: EIK94707.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: PMM47T1_20543
symbol: rapA
gene_biotype: protein_coding
description:
  ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: PMM47T1_20558
symbol: EIK94726.1
gene_biotype: protein_coding
description:
  Signaling repeat/GGDEF domain/EAL domain-containing protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: PMM47T1_20573
symbol: EIK94729.1
gene_biotype: protein_coding
description:
  Leucine ABC transporter subunit substrate-binding protein LivK; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: PMM47T1_20578
symbol: EIK94730.1
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PMM47T1_20583
symbol: livM
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter permease subunit; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PMM47T1_20588
symbol: livG
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter ATP-binding subunit; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: PMM47T1_20593
symbol: EIK94733.1
gene_biotype: protein_coding
description:
  COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_20618
symbol: nhaA
gene_biotype: protein_coding
description:
  pH-dependent sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: PMM47T1_20628
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: PMM47T1_20803
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: PMM47T1_20813
symbol: EIK94570.1
gene_biotype: protein_coding
description:
  manganese(II)/zinc(II) ABC transporter ATP-binding protein; COG1121 ABC-type Mn/Zn transport systems, ATPase component.


ensembl_gene_id: PMM47T1_20823
symbol: EIK94572.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: PMM47T1_20903
symbol: EIK94588.1
gene_biotype: protein_coding
description:
  GAF domain/cyclic diguanylate phosphodiesterase (EAL) domain-containing protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: PMM47T1_20908
symbol: EIK94589.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: PMM47T1_20953
symbol: EIK94598.1
gene_biotype: protein_coding
description:
  Pyruvate decarboxylase:pyruvate decarboxylase; COG3962 Acetolactate synthase; Belongs to the TPP enzyme family.


ensembl_gene_id: PMM47T1_20963
symbol: EIK94600.1
gene_biotype: protein_coding
description:
  Ribose ABC transporter periplasmic protein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: PMM47T1_20968
symbol: rbsA
gene_biotype: protein_coding
description:
  Ribose ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: PMM47T1_20973
symbol: EIK94602.1
gene_biotype: protein_coding
description:
  Putative ABC transporter permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: PMM47T1_21018
symbol: EIK94611.1
gene_biotype: protein_coding
description:
  Histidine transporter, periplasmic histidine-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_21053
symbol: EIK94618.1
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal and cupin region containing protein; COG4297 Uncharacterized protein containing double-stranded beta helix domain.


ensembl_gene_id: PMM47T1_21063
symbol: EIK94620.1
gene_biotype: protein_coding
description:
  Taurine ABC transporter ATPase; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: PMM47T1_21068
symbol: EIK94621.1
gene_biotype: protein_coding
description:
  Taurine ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_21088
symbol: EIK94623.1
gene_biotype: protein_coding
description:
  Membrane-bound D-gluconate 2-dehydrogenase cytochrome c subunit; COG2010 Cytochrome c, mono- and diheme variants.


ensembl_gene_id: PMM47T1_21138
symbol: EIK94633.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_21223
symbol: EIK94650.1
gene_biotype: protein_coding
description:
  Dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein; COG1073 Hydrolases of the alpha/beta superfamily.


ensembl_gene_id: PMM47T1_21243
symbol: EIK94654.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase/reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_21283
symbol: EIK94466.1
gene_biotype: protein_coding
description:
  Isoprenoid biosynthesis protein with amidotransferase-like domain; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: PMM47T1_21298
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: PMM47T1_21313
symbol: EIK94472.1
gene_biotype: protein_coding
description:
  Putative ABC transporter membrane protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: PMM47T1_21338
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: PMM47T1_21348
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: PMM47T1_21363
symbol: EIK94482.1
gene_biotype: protein_coding
description:
  ChaC-like protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: PMM47T1_21373
symbol: EIK94484.1
gene_biotype: protein_coding
description:
  Putative sinc-binding oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_21378
symbol: EIK94485.1
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL-like protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: PMM47T1_21393
symbol: EIK94488.1
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: PMM47T1_21398
symbol: EIK94489.1
gene_biotype: protein_coding
description:
  Cell division protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: PMM47T1_21428
symbol: EIK94495.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: PMM47T1_21433
symbol: EIK94496.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: PMM47T1_21438
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: PMM47T1_21488
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: PMM47T1_21513
symbol: rimK
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the RimK family.


ensembl_gene_id: PMM47T1_21523
symbol: EIK94514.1
gene_biotype: protein_coding
description:
  COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); Belongs to the HSP15 family.


ensembl_gene_id: PMM47T1_21533
symbol: hslO
gene_biotype: protein_coding
description:
  Hsp33-like chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: PMM47T1_21538
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: PMM47T1_21563
symbol: fdhD
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: PMM47T1_21573
symbol: nudE
gene_biotype: protein_coding
description:
  Adenosine nucleotide hydrolase NudE; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: PMM47T1_21578
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: PMM47T1_21588
symbol: EIK94527.1
gene_biotype: protein_coding
description:
  Two component, sigma-54 specific, Fis family transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: PMM47T1_21598
symbol: EIK94529.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: PMM47T1_21603
symbol: EIK94530.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: PMM47T1_21608
symbol: EIK94531.1
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: PMM47T1_21613
symbol: EIK94532.1
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: PMM47T1_21623
symbol: aguA-2
gene_biotype: protein_coding
description:
  Agmatine deiminase; Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.


ensembl_gene_id: PMM47T1_21653
symbol: EIK94540.1
gene_biotype: protein_coding
description:
  Outer membrane autotransporter barrel domain-containing protein; COG3468 Type V secretory pathway, adhesin AidA.


ensembl_gene_id: PMM47T1_21778
symbol: EIK94378.1
gene_biotype: protein_coding
description:
  Oxidoreductase, aryl-alcohol dehydrogenase like protein; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_21823
symbol: EIK94387.1
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.


ensembl_gene_id: PMM47T1_21883
symbol: EIK94399.1
gene_biotype: protein_coding
description:
  Regulatory protein LysR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PMM47T1_21893
symbol: EIK94401.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: PMM47T1_21938
symbol: EIK94410.1
gene_biotype: protein_coding
description:
  ABC transporter transmembrane protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: PMM47T1_21943
symbol: EIK94411.1
gene_biotype: protein_coding
description:
  CsbD family protein; COG3237 Uncharacterized protein conserved in bacteria; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: PMM47T1_21968
symbol: EIK94416.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (cytochrome); COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: PMM47T1_22043
symbol: EIK94431.1
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase (NADP+); COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PMM47T1_22058
symbol: EIK94434.1
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: PMM47T1_22068
symbol: EIK94436.1
gene_biotype: protein_coding
description:
  Peptide ABC transporter ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_22083
symbol: EIK94439.1
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: PMM47T1_22133
symbol: EIK94449.1
gene_biotype: protein_coding
description:
  Aldehyde oxidase and xanthine dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: PMM47T1_22138
symbol: EIK94450.1
gene_biotype: protein_coding
description:
  Oxidoreductase, molybdopterin-binding subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: PMM47T1_22213
symbol: EIK94310.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: PMM47T1_22223
symbol: EIK94312.1
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: PMM47T1_22238
symbol: EIK94315.1
gene_biotype: protein_coding
description:
  Glyoxylate reductase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PMM47T1_22263
symbol: EIK94320.1
gene_biotype: protein_coding
description:
  Polyamine ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.


ensembl_gene_id: PMM47T1_22298
symbol: EIK94327.1
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthetase modules, amino acid adenylation, pyoverdine; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: PMM47T1_22328
symbol: EIK94333.1
gene_biotype: protein_coding
description:
  Iron-hydroxamate transporter permease subunit; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PMM47T1_22333
symbol: EIK94334.1
gene_biotype: protein_coding
description:
  iron(III)-siderophore-binding periplasmic protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_22338
symbol: EIK94335.1
gene_biotype: protein_coding
description:
  Cyclic peptide transporter; COG4615 ABC-type siderophore export system, fused ATPase and permease components.


ensembl_gene_id: PMM47T1_22363
symbol: EIK94340.1
gene_biotype: protein_coding
description:
  COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes.


ensembl_gene_id: PMM47T1_22368
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: PMM47T1_22373
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: PMM47T1_22378
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: PMM47T1_22383
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: PMM47T1_22388
symbol: ipk
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: PMM47T1_22393
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: PMM47T1_22403
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: PMM47T1_22408
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: PMM47T1_22413
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: PMM47T1_22418
symbol: EIK94351.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeB; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: PMM47T1_22428
symbol: EIK94353.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.


ensembl_gene_id: PMM47T1_22453
symbol: EIK94358.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_22478
symbol: EIK94363.1
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers; Belongs to the bacterial renalase family.


ensembl_gene_id: PMM47T1_22488
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: PMM47T1_22537
symbol: EIK94218.1
gene_biotype: protein_coding
description:
  Glyoxylate/hydroxypyruvate reductase B; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PMM47T1_22597
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: PMM47T1_22602
symbol: EIK94231.1
gene_biotype: protein_coding
description:
  COG1972 Nucleoside permease; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: PMM47T1_22607
symbol: EIK94232.1
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PMM47T1_22612
symbol: EIK94233.1
gene_biotype: protein_coding
description:
  Aldo-keto reductase family protein; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: PMM47T1_22632
symbol: rutA
gene_biotype: protein_coding
description:
  Luciferase; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate.


ensembl_gene_id: PMM47T1_22637
symbol: rutB
gene_biotype: protein_coding
description:
  Isochorismatase family protein; In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2; Belongs to the isochorismatase family. RutB subfamily.


ensembl_gene_id: PMM47T1_22642
symbol: rutC
gene_biotype: protein_coding
description:
  Endoribonuclease L-PSP; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation.


ensembl_gene_id: PMM47T1_22647
symbol: rutD
gene_biotype: protein_coding
description:
  Alpha/beta fold family hydrolase; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family.


ensembl_gene_id: PMM47T1_22657
symbol: EIK94242.1
gene_biotype: protein_coding
description:
  Dipeptidyl aminopeptidase/acylaminoacyl-peptidase related protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_22677
symbol: vapC
gene_biotype: protein_coding
description:
  Hypothetical protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: PMM47T1_22732
symbol: cobB
gene_biotype: protein_coding
description:
  Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.


ensembl_gene_id: PMM47T1_22752
symbol: EIK94257.1
gene_biotype: protein_coding
description:
  Tannase and feruloyl esterase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: PMM47T1_22787
symbol: EIK94264.1
gene_biotype: protein_coding
description:
  COG2995 Uncharacterized paraquat-inducible protein A; overlaps another CDS with the same product name.


ensembl_gene_id: PMM47T1_22862
symbol: EIK94279.1
gene_biotype: protein_coding
description:
  Putative inner membrane component of binding-protein-dependent transport system; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: PMM47T1_22867
symbol: EIK94280.1
gene_biotype: protein_coding
description:
  Putative lipoprotein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: PMM47T1_22877
symbol: EIK94282.1
gene_biotype: protein_coding
description:
  PilT domain-containing protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.


ensembl_gene_id: PMM47T1_22937
symbol: EIK94292.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase sdr precursor; COG4221 Short-chain alcohol dehydrogenase of unknown specificity.


ensembl_gene_id: PMM47T1_22947
symbol: EIK94294.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate TPP binding domain-containing protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: PMM47T1_22972
symbol: xylG
gene_biotype: protein_coding
description:
  Xylose transporter ATP-binding subunit; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.


ensembl_gene_id: PMM47T1_22977
symbol: EIK94300.1
gene_biotype: protein_coding
description:
  COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PMM47T1_22997
symbol: lldD
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.


ensembl_gene_id: PMM47T1_23007
symbol: EIK94135.1
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: PMM47T1_23022
symbol: EIK94138.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_23057
symbol: EIK94143.1
gene_biotype: protein_coding
description:
  Oxidoreductase subunit alpha; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: PMM47T1_23062
symbol: EIK94144.1
gene_biotype: protein_coding
description:
  Putative vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: PMM47T1_23107
symbol: EIK94153.1
gene_biotype: protein_coding
description:
  AlgI-like alginate biosynthesis protein; COG1696 Predicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: PMM47T1_23137
symbol: EIK94159.1
gene_biotype: protein_coding
description:
  Flavin reductase-like protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: PMM47T1_23157
symbol: ribB
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: PMM47T1_23172
symbol: EIK94166.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: PMM47T1_23177
symbol: EIK94167.1
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATP-binding subunit; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PMM47T1_23182
symbol: EIK94168.1
gene_biotype: protein_coding
description:
  Cytosine/purines, uracil, thiamine, allantoin permease; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: PMM47T1_23212
symbol: EIK94174.1
gene_biotype: protein_coding
description:
  Putative glutamate synthase large subunit; COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.


ensembl_gene_id: PMM47T1_23232
symbol: EIK94178.1
gene_biotype: protein_coding
description:
  Helix-hairpin-helix DNA-binding motif-containing protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: PMM47T1_23292
symbol: EIK94190.1
gene_biotype: protein_coding
description:
  NAD(P)H-dependent quinone oxidoreductase; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: PMM47T1_23322
symbol: EIK94196.1
gene_biotype: protein_coding
description:
  COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family.


ensembl_gene_id: PMM47T1_23382
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: PMM47T1_23387
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...]


ensembl_gene_id: PMM47T1_23392
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: PMM47T1_23402
symbol: EIK94057.1
gene_biotype: protein_coding
description:
  RND transporter, heavy metal efflux (HME) family permease; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: PMM47T1_23447
symbol: EIK94066.1
gene_biotype: protein_coding
description:
  Phosphonate ABC transporter substrate-binding protein; COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_23452
symbol: phnC
gene_biotype: protein_coding
description:
  Phosphate/phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: PMM47T1_23462
symbol: EIK94069.1
gene_biotype: protein_coding
description:
  Phosphonate ABC transporter, inner membrane subunit; COG3639 ABC-type phosphate/phosphonate transport system, permease component.


ensembl_gene_id: PMM47T1_23467
symbol: EIK94070.1
gene_biotype: protein_coding
description:
  Phosphonate metabolism-associated iron-containing alcohol dehydrogenase; COG1454 Alcohol dehydrogenase, class IV.


ensembl_gene_id: PMM47T1_23537
symbol: EIK94084.1
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase domain-containing protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: PMM47T1_23692
symbol: argD-2
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: PMM47T1_23722
symbol: EIK94121.1
gene_biotype: protein_coding
description:
  ABC transporter, periplasmic substrate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_23737
symbol: EIK94124.1
gene_biotype: protein_coding
description:
  Methyltransferase; COG1092 Predicted SAM-dependent methyltransferases; Belongs to the methyltransferase superfamily.


ensembl_gene_id: PMM47T1_23742
symbol: EIK94125.1
gene_biotype: protein_coding
description:
  Iron complex transport system substrate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: PMM47T1_23747
symbol: EIK94126.1
gene_biotype: protein_coding
description:
  Iron ABC transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PMM47T1_23752
symbol: EIK94127.1
gene_biotype: protein_coding
description:
  Fe(3+) dicitrate transport ATP-binding protein fecE; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: PMM47T1_23767
symbol: EIK94130.1
gene_biotype: protein_coding
description:
  DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: PMM47T1_23772
symbol: lon-2
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: PMM47T1_23777
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: PMM47T1_23782
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: PMM47T1_23787
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: PMM47T1_23794
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: PMM47T1_23799
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: PMM47T1_23829
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: PMM47T1_23834
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: PMM47T1_23839
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: PMM47T1_23844
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: PMM47T1_23849
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: PMM47T1_23854
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: PMM47T1_23859
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: PMM47T1_23864
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: PMM47T1_23869
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: PMM47T1_23874
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: PMM47T1_23879
symbol: EIK93988.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: PMM47T1_23884
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: PMM47T1_23889
symbol: rrmJ
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: PMM47T1_23904
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: PMM47T1_23919
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: PMM47T1_23924
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: PMM47T1_23934
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: PMM47T1_23949
symbol: bamE
gene_biotype: protein_coding
description:
  SmpA/OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PMM47T1_23964
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: PMM47T1_23969
symbol: EIK94006.1
gene_biotype: protein_coding
description:
  Lactate-responsive regulator LldR in Enterobacteria, GntR family protein; COG2186 Transcriptional regulators.


ensembl_gene_id: PMM47T1_23974
symbol: EIK94007.1
gene_biotype: protein_coding
description:
  Glycolate permease GlcA; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: PMM47T1_23984
symbol: EIK94009.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster binding protein; COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain.


ensembl_gene_id: PMM47T1_24223
symbol: EIK93897.1
gene_biotype: protein_coding
description:
  ImpA family type VI secretion-associated protein; COG3501 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PMM47T1_24238
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: PMM47T1_24258
symbol: EIK93904.1
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: PMM47T1_24308
symbol: EIK93914.1
gene_biotype: protein_coding
description:
  Periplasmic solute binding protein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: PMM47T1_24318
symbol: EIK93916.1
gene_biotype: protein_coding
description:
  Cation ABC transporter ATP-binding protein; COG1121 ABC-type Mn/Zn transport systems, ATPase component.


ensembl_gene_id: PMM47T1_24333
symbol: EIK93919.1
gene_biotype: protein_coding
description:
  Arogenate dehydratase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_24348
symbol: EIK93922.1
gene_biotype: protein_coding
description:
  Prolipoprotein signal peptidase (Signal peptidase II.); This protein specifically catalyzes the removal of signal peptides from prolipoproteins.


ensembl_gene_id: PMM47T1_24353
symbol: EIK93923.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES-like protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: PMM47T1_24363
symbol: EIK93925.1
gene_biotype: protein_coding
description:
  Acyloate catabolism-like protein; COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog.


ensembl_gene_id: PMM47T1_24373
symbol: sotB
gene_biotype: protein_coding
description:
  Putative arabinose transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: PMM47T1_24393
symbol: EIK93931.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: PMM47T1_24398
symbol: EIK93932.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: PMM47T1_24403
symbol: fabV
gene_biotype: protein_coding
description:
  trans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: PMM47T1_24413
symbol: clsB
gene_biotype: protein_coding
description:
  Cardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: PMM47T1_24428
symbol: EIK93938.1
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_24513
symbol: araH
gene_biotype: protein_coding
description:
  L-arabinose transporter permease protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: PMM47T1_24518
symbol: araG
gene_biotype: protein_coding
description:
  L-arabinose transporter ATP-binding protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.


ensembl_gene_id: PMM47T1_24523
symbol: EIK93957.1
gene_biotype: protein_coding
description:
  Arabinose ABC transporter L-arabinose-binding periplasmic protein AraF; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: PMM47T1_24538
symbol: mrdA-2
gene_biotype: protein_coding
description:
  Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: PMM47T1_24563
symbol: EIK93965.1
gene_biotype: protein_coding
description:
  Two component winged helix family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: PMM47T1_24630
symbol: EIK93820.1
gene_biotype: protein_coding
description:
  Radical SAM family protein; COG4277 Predicted DNA-binding protein with the Helix-hairpin-helix motif.


ensembl_gene_id: PMM47T1_24635
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: PMM47T1_24640
symbol: EIK93822.1
gene_biotype: protein_coding
description:
  Geranyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PMM47T1_24645
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: PMM47T1_24655
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: PMM47T1_24665
symbol: EIK93827.1
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: PMM47T1_24670
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: PMM47T1_24675
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: PMM47T1_24680
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: PMM47T1_24695
symbol: EIK93833.1
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: PMM47T1_24700
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: PMM47T1_24730
symbol: EIK93840.1
gene_biotype: protein_coding
description:
  Methionine ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: PMM47T1_24775
symbol: EIK93849.1
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: PMM47T1_24805
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PMM47T1_24810
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: PMM47T1_24815
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: PMM47T1_24820
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: PMM47T1_24830
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: PMM47T1_24835
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: PMM47T1_24845
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: PMM47T1_24850
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: PMM47T1_24855
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: PMM47T1_24860
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: PMM47T1_24865
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: PMM47T1_24870
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: PMM47T1_24875
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: PMM47T1_24880
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: PMM47T1_24885
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: PMM47T1_24895
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: PMM47T1_24900
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: PMM47T1_24905
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: PMM47T1_24910
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: PMM47T1_24915
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: PMM47T1_24920
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: PMM47T1_24930
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: PMM47T1_24935
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: PMM47T1_24940
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: PMM47T1_24945
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: PMM47T1_24950
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: PMM47T1_24955
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: PMM47T1_24960
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PMM47T1_24970
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: PMM47T1_24975
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: PMM47T1_24980
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: PMM47T1_24985
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: PMM47T1_24990
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: PMM47T1_24995
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: PMM47T1_25005
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: PMM47T1_25010
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: PMM47T1_25043
symbol: EIK93742.1
gene_biotype: protein_coding
description:
  Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: PMM47T1_25088
symbol: EIK93749.1
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PMM47T1_25213
symbol: EIK93774.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: PMM47T1_25293
symbol: EIK93786.1
gene_biotype: protein_coding
description:
  Arsenical pump membrane protein; COG1055 Na+/H+ antiporter NhaD and related arsenite permeases; overlaps another CDS with the same product name.


ensembl_gene_id: PMM47T1_25433
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: PMM47T1_25478
symbol: EIK93675.1
gene_biotype: protein_coding
description:
  cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: PMM47T1_25483
symbol: cobB-2
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: PMM47T1_25493
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: PMM47T1_25498
symbol: EIK93679.1
gene_biotype: protein_coding
description:
  Threonine-phosphate decarboxylase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: PMM47T1_25503
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: PMM47T1_25508
symbol: cobU
gene_biotype: protein_coding
description:
  Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: PMM47T1_25513
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: PMM47T1_25523
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: PMM47T1_25553
symbol: EIK93690.1
gene_biotype: protein_coding
description:
  K+ transporter Trk; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: PMM47T1_25588
symbol: EIK93697.1
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: PMM47T1_25603
symbol: EIK93700.1
gene_biotype: protein_coding
description:
  Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: PMM47T1_25608
symbol: EIK93701.1
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: PMM47T1_25618
symbol: EIK93703.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PMM47T1_25623
symbol: EIK93704.1
gene_biotype: protein_coding
description:
  Aromatic amino acid transport protein AroP; COG1113 Gamma-aminobutyrate permease and related permeases.


ensembl_gene_id: PMM47T1_25668
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: PMM47T1_25673
symbol: EIK93714.1
gene_biotype: protein_coding
description:
  Arginine/ornithine ABC transporter periplasmic arginine/ornithine-binding protein AotJ; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: PMM47T1_25678
symbol: EIK93715.1
gene_biotype: protein_coding
description:
  Arginine/ornithine ABC transporter permease AotQ; COG4215 ABC-type arginine transport system, permease component.


ensembl_gene_id: PMM47T1_25703
symbol: argD
gene_biotype: protein_coding
description:
  Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: PMM47T1_25718
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: PMM47T1_25723
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: PMM47T1_25733
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: PMM47T1_25738
symbol: ribH-2
gene_biotype: protein_coding
description:
  Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: PMM47T1_25743
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: PMM47T1_25773
symbol: phnN
gene_biotype: protein_coding
description:
  Phosphonate metabolism protein/1,5-bisphosphokinase PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).


ensembl_gene_id: PMM47T1_25813
symbol: cobB-3
gene_biotype: protein_coding
description:
  COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: PMM47T1_25833
symbol: EIK93615.1
gene_biotype: protein_coding
description:
  Putative periplasmic ligand-binding sensor protein; COG3416 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: PMM47T1_25848
symbol: EIK93618.1
gene_biotype: protein_coding
description:
  Putative DMT superfamily transporter inner membrane protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: PMM47T1_25863
symbol: EIK93621.1
gene_biotype: protein_coding
description:
  Putative histone deacetylase family protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: PMM47T1_25908
symbol: EIK93630.1
gene_biotype: protein_coding
description:
  Putative FAD-binding dehydrogenase; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.


