# geneInfo

ensembl_gene_id: C266_00015
symbol: C266_00015
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: C266_00020
symbol: C266_00020
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: C266_00025
symbol: C266_00025
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: C266_00030
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: C266_00035
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: C266_00040
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: C266_00045
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: C266_00050
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: C266_00070
symbol: C266_00070
gene_biotype: protein_coding
description:
  Major facilitator superfamily efflux pump outer membrane lipoprotein; COG1538 Outer membrane protein.


ensembl_gene_id: C266_00095
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: C266_00100
symbol: C266_00100
gene_biotype: protein_coding
description:
  Sulfate ABC transporter substrate-binding protein; COG1613 ABC-type sulfate transport system, periplasmic component.


ensembl_gene_id: C266_00105
symbol: C266_00105
gene_biotype: protein_coding
description:
  Sulfate ABC transporter permease; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: C266_00110
symbol: C266_00110
gene_biotype: protein_coding
description:
  Sulfate ABC transporter inner membrane subunit CysW; COG4208 ABC-type sulfate transport system, permease component.


ensembl_gene_id: C266_00115
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter ATPase; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: C266_00125
symbol: C266_00125
gene_biotype: protein_coding
description:
  Type II L-asparaginase; COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; Belongs to the asparaginase 1 family.


ensembl_gene_id: C266_00130
symbol: C266_00130
gene_biotype: protein_coding
description:
  Tartronate semialdehyde reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: C266_00155
symbol: priB
gene_biotype: protein_coding
description:
  Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: C266_00160
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: C266_00170
symbol: C266_00170
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: C266_00200
symbol: C266_00200
gene_biotype: protein_coding
description:
  PhoH family protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: C266_00215
symbol: C266_00215
gene_biotype: protein_coding
description:
  NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: C266_00225
symbol: C266_00225
gene_biotype: protein_coding
description:
  Polymixin resistance glycosyltransferase transmembrane protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: C266_00230
symbol: C266_00230
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: C266_00265
symbol: C266_00265
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain-containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: C266_00285
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: C266_00340
symbol: C266_00340
gene_biotype: protein_coding
description:
  Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: C266_00350
symbol: C266_00350
gene_biotype: protein_coding
description:
  Peptidase M22 glycoprotease; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: C266_00380
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: C266_00385
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: C266_00395
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: C266_00400
symbol: prmB
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: C266_00405
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: C266_00415
symbol: dapD
gene_biotype: protein_coding
description:
  COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: C266_00430
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: C266_00435
symbol: C266_00435
gene_biotype: protein_coding
description:
  ZipA FtsZ-binding region; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.


ensembl_gene_id: C266_00440
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: C266_00445
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: C266_00450
symbol: C266_00450
gene_biotype: protein_coding
description:
  COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: C266_00455
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: C266_00460
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: C266_00470
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: C266_00480
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: C266_00485
symbol: C266_00485
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: C266_00495
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: C266_00505
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: C266_00515
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: C266_00520
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: C266_00525
symbol: lpxA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: C266_00530
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: C266_00545
symbol: C266_00545
gene_biotype: protein_coding
description:
  PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: C266_00550
symbol: C266_00550
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: C266_00570
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: C266_00590
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: C266_00620
symbol: C266_00620
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_00660
symbol: C266_00660
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: C266_00670
symbol: C266_00670
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: C266_00680
symbol: C266_00680
gene_biotype: protein_coding
description:
  Short chain dehydrogenase/reductase family oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_00710
symbol: dkgB
gene_biotype: protein_coding
description:
  2,5-diketo-D-gluconate reductase B; COG0656 Aldo/keto reductases, related to diketogulonate reductase.


ensembl_gene_id: C266_00715
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: C266_00745
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: C266_00750
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: C266_00760
symbol: C266_00760
gene_biotype: protein_coding
description:
  NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: C266_00765
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: C266_00770
symbol: zapD
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: C266_00775
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: C266_00780
symbol: C266_00780
gene_biotype: protein_coding
description:
  COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Belongs to the peptidase A24 family.


ensembl_gene_id: C266_00805
symbol: C266_00805
gene_biotype: protein_coding
description:
  Trans-hexaprenyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: C266_00810
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: C266_00820
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: C266_00825
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: C266_00835
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: C266_00840
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyla [...]


ensembl_gene_id: C266_00855
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: C266_00860
symbol: C266_00860
gene_biotype: protein_coding
description:
  Cytochrome c assembly protein; COG4137 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: C266_00870
symbol: C266_00870
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: C266_00875
symbol: C266_00875
gene_biotype: protein_coding
description:
  N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression.


ensembl_gene_id: C266_00880
symbol: C266_00880
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: C266_00890
symbol: C266_00890
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: C266_00910
symbol: tpx
gene_biotype: protein_coding
description:
  Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: C266_00920
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: C266_00925
symbol: C266_00925
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: C266_00930
symbol: C266_00930
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: C266_00935
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: C266_00950
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:l-alanyl-gamma-d-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: C266_00970
symbol: C266_00970
gene_biotype: protein_coding
description:
  Beta-hydroxylase, aspartyl/asparaginyl family protein; COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases.


ensembl_gene_id: C266_00975
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: C266_00980
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: C266_00990
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: C266_00995
symbol: pyrF
gene_biotype: protein_coding
description:
  COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: C266_01000
symbol: C266_01000
gene_biotype: protein_coding
description:
  CinA-like competence-damaged protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: C266_01005
symbol: C266_01005
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: C266_01010
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: C266_01035
symbol: C266_01035
gene_biotype: protein_coding
description:
  COG0583 Transcriptional regulator; overlaps another CDS with the same product name; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_01045
symbol: C266_01045
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_01055
symbol: C266_01055
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: C266_01060
symbol: C266_01060
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: C266_01065
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.


ensembl_gene_id: C266_01075
symbol: C266_01075
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase, type I; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: C266_01085
symbol: bamE
gene_biotype: protein_coding
description:
  Lipoprotein, SmpA/OmlA family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: C266_01090
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: C266_01100
symbol: lptE
gene_biotype: protein_coding
description:
  Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.


ensembl_gene_id: C266_01110
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: C266_01120
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: C266_01125
symbol: C266_01125
gene_biotype: protein_coding
description:
  DNA-binding protein Fis; COG2901 Factor for inversion stimulation Fis, transcriptional activator; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: C266_01130
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: C266_01135
symbol: C266_01135
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_01145
symbol: C266_01145
gene_biotype: protein_coding
description:
  Sugar-phosphate nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: C266_01155
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: C266_01160
symbol: surA
gene_biotype: protein_coding
description:
  SurA domain-containing protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: C266_01165
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: C266_01170
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: C266_01175
symbol: C266_01175
gene_biotype: protein_coding
description:
  Putative membrane lipoprotein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: C266_01185
symbol: cpdA
gene_biotype: protein_coding
description:
  Phosphoesterase-like protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: C266_01190
symbol: C266_01190
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: C266_01195
symbol: C266_01195
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: C266_01205
symbol: C266_01205
gene_biotype: protein_coding
description:
  Sn-glycerol-3-phosphate import ATP-binding protein UgpC; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_01250
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: C266_01260
symbol: C266_01260
gene_biotype: protein_coding
description:
  ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: C266_01265
symbol: ybeY
gene_biotype: protein_coding
description:
  Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: C266_01275
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: C266_01280
symbol: C266_01280
gene_biotype: protein_coding
description:
  ZnuA; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: C266_01320
symbol: C266_01320
gene_biotype: protein_coding
description:
  Glycine betaine/choline/proline ABC transporter inner membrane protein; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: C266_01325
symbol: C266_01325
gene_biotype: protein_coding
description:
  COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: C266_01330
symbol: C266_01330
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: C266_01345
symbol: C266_01345
gene_biotype: protein_coding
description:
  NADH-flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: C266_01370
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: C266_01385
symbol: C266_01385
gene_biotype: protein_coding
description:
  Nitrate ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: C266_01435
symbol: C266_01435
gene_biotype: protein_coding
description:
  Two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_01440
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: C266_01455
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: C266_01460
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: C266_01470
symbol: C266_01470
gene_biotype: protein_coding
description:
  Type IV fimbrial pilin protein; COG4969 Tfp pilus assembly protein, major pilin PilA; Belongs to the N-Me-Phe pilin family.


ensembl_gene_id: C266_01495
symbol: C266_01495
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: C266_01500
symbol: C266_01500
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: C266_01505
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: C266_01520
symbol: apaH
gene_biotype: protein_coding
description:
  Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: C266_01525
symbol: C266_01525
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: C266_01545
symbol: C266_01545
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: C266_01565
symbol: C266_01565
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: C266_01580
symbol: C266_01580
gene_biotype: protein_coding
description:
  protein-L-isoaspartate(D-aspartate) O-methyltransferase; COG2518 Protein-L-isoaspartate carboxylmethyltransferase.


ensembl_gene_id: C266_01605
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: C266_01610
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: C266_01674
symbol: cyaY
gene_biotype: protein_coding
description:
  Frataxin-like protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: C266_01679
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: C266_01684
symbol: msrQ
gene_biotype: protein_coding
description:
  Sulfite oxidase subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, u [...]


ensembl_gene_id: C266_01689
symbol: msrP
gene_biotype: protein_coding
description:
  TMAO/DMSO reductase; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) [...]


ensembl_gene_id: C266_01709
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: C266_01719
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein (Protein-disulfide reductase); Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: C266_01734
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: C266_01739
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: C266_01744
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: C266_01749
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: C266_01759
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: C266_01764
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: C266_01769
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: C266_01779
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: C266_01784
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: C266_01789
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: C266_01794
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: C266_01799
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: C266_01804
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: C266_01809
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: C266_01814
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: C266_01819
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: C266_01829
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: C266_01834
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: C266_01839
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: C266_01844
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: C266_01849
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: C266_01854
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: C266_01864
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: C266_01869
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: C266_01874
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: C266_01879
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: C266_01884
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: C266_01889
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: C266_01894
symbol: C266_01894
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: C266_01944
symbol: C266_01944
gene_biotype: protein_coding
description:
  Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_01974
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: C266_01984
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: C266_01989
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: C266_01994
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: C266_01999
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: C266_02004
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: C266_02009
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: C266_02041
symbol: C266_02041
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_02046
symbol: C266_02046
gene_biotype: protein_coding
description:
  Glycine betaine ABC transporter substrate-binding protein; COG4521 ABC-type taurine transport system, periplasmic component.


ensembl_gene_id: C266_02051
symbol: C266_02051
gene_biotype: protein_coding
description:
  LysR family regulatory protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_02066
symbol: C266_02066
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: C266_02081
symbol: C266_02081
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: C266_02116
symbol: C266_02116
gene_biotype: protein_coding
description:
  Chain amino acid ABC transporter substrate binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_02131
symbol: C266_02131
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: C266_02136
symbol: C266_02136
gene_biotype: protein_coding
description:
  Aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_02161
symbol: C266_02161
gene_biotype: protein_coding
description:
  RNA-metabolising metallo-beta-lactamase; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: C266_02176
symbol: C266_02176
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: C266_02181
symbol: C266_02181
gene_biotype: protein_coding
description:
  Crp/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: C266_02201
symbol: C266_02201
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: C266_02206
symbol: C266_02206
gene_biotype: protein_coding
description:
  COG0462 Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family.


ensembl_gene_id: C266_02226
symbol: C266_02226
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: C266_02251
symbol: C266_02251
gene_biotype: protein_coding
description:
  Natural resistance-associated macrophage protein; COG1914 Mn2+ and Fe2+ transporters of the NRAMP family.


ensembl_gene_id: C266_02286
symbol: C266_02286
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: C266_02441
symbol: C266_02441
gene_biotype: protein_coding
description:
  NMT1/THI5-like domain-containing protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_02451
symbol: C266_02451
gene_biotype: protein_coding
description:
  NitT/TauT family transport system ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: C266_02466
symbol: C266_02466
gene_biotype: protein_coding
description:
  2OG-Fe(II) oxygenase; COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: C266_02471
symbol: C266_02471
gene_biotype: protein_coding
description:
  2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: C266_02491
symbol: C266_02491
gene_biotype: protein_coding
description:
  Autotransporter; COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain.


ensembl_gene_id: C266_02626
symbol: C266_02626
gene_biotype: protein_coding
description:
  Putative ABC transporter, glutamate receptor; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_02651
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: C266_02656
symbol: C266_02656
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: C266_02661
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: C266_02676
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: C266_02681
symbol: C266_02681
gene_biotype: protein_coding
description:
  dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: C266_02686
symbol: C266_02686
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: C266_02706
symbol: C266_02706
gene_biotype: protein_coding
description:
  L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: C266_02726
symbol: C266_02726
gene_biotype: protein_coding
description:
  Putative two-component response regulator transcriptional regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_02741
symbol: C266_02741
gene_biotype: protein_coding
description:
  Type I phosphodiesterase/nucleotide pyrophosphatase; COG1524 Uncharacterized proteins of the AP superfamily.


ensembl_gene_id: C266_02818
symbol: C266_02818
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: C266_02878
symbol: hldD
gene_biotype: protein_coding
description:
  ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: C266_02883
symbol: C266_02883
gene_biotype: protein_coding
description:
  D-beta-D-heptose 7-phosphate kinase; COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase.


ensembl_gene_id: C266_02893
symbol: lapB
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: C266_02903
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: C266_02908
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: C266_02918
symbol: mntH
gene_biotype: protein_coding
description:
  Mn2+/Fe2+ transporter; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: C266_02923
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: C266_02938
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: C266_02948
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: C266_02953
symbol: C266_02953
gene_biotype: protein_coding
description:
  OmpA-OmpF porin, OOP family protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: C266_02988
symbol: C266_02988
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter, DctM subunit; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: C266_02998
symbol: C266_02998
gene_biotype: protein_coding
description:
  C4-dicarboxylate-binding periplasmic protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: C266_03008
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: C266_03043
symbol: pepA
gene_biotype: protein_coding
description:
  Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: C266_03048
symbol: C266_03048
gene_biotype: protein_coding
description:
  YjgP/YjgQ family permease; COG0795 Predicted permeases; overlaps another CDS with the same product name.


ensembl_gene_id: C266_03063
symbol: C266_03063
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: C266_03068
symbol: C266_03068
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: C266_03073
symbol: C266_03073
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: C266_03103
symbol: C266_03103
gene_biotype: protein_coding
description:
  Tartronic semialdehyde reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: C266_03123
symbol: C266_03123
gene_biotype: protein_coding
description:
  Transcriptional regulator lambda-like DNA-binding repressor; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: C266_03128
symbol: C266_03128
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: C266_03143
symbol: vapC
gene_biotype: protein_coding
description:
  PilT domain-containing protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: C266_03168
symbol: C266_03168
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: C266_03178
symbol: C266_03178
gene_biotype: protein_coding
description:
  Monooxygenase, FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_03233
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: C266_03248
symbol: glk
gene_biotype: protein_coding
description:
  Bifunctional glucokinase/RpiR family transcriptional regulator; COG0837 Glucokinase; Belongs to the bacterial glucokinase family.


ensembl_gene_id: C266_03258
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: C266_03263
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: C266_03273
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: C266_03288
symbol: C266_03288
gene_biotype: protein_coding
description:
  3'-hydroxymethylcephem-O-carbamoyltransferase; COG2192 Predicted carbamoyl transferase, NodU family.


ensembl_gene_id: C266_03333
symbol: C266_03333
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: C266_03358
symbol: C266_03358
gene_biotype: protein_coding
description:
  Leucine ABC transporter subunit substrate-binding protein LivK; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: C266_03363
symbol: C266_03363
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_03368
symbol: livM
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter permease subunit; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_03373
symbol: livG
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter ATP-binding subunit; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_03378
symbol: C266_03378
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_03393
symbol: ribB
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: C266_03398
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: C266_03403
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: C266_03413
symbol: C266_03413
gene_biotype: protein_coding
description:
  Slt family transglycosylase; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: C266_03418
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: C266_03423
symbol: C266_03423
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase I, NADP-dependent; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: C266_03438
symbol: C266_03438
gene_biotype: protein_coding
description:
  YaeC family lipoprotein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: C266_03443
symbol: C266_03443
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG2011 ABC-type metal ion transport system, permease component.


ensembl_gene_id: C266_03448
symbol: metN
gene_biotype: protein_coding
description:
  DL-methionine transporter ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: C266_03473
symbol: C266_03473
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; COG5278 Predicted periplasmic ligand-binding sensor domain.


ensembl_gene_id: C266_03493
symbol: C266_03493
gene_biotype: protein_coding
description:
  LysR family transcription regulator protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_03523
symbol: C266_03523
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_03543
symbol: C266_03543
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: C266_03593
symbol: C266_03593
gene_biotype: protein_coding
description:
  Lateral flagellin LafA; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: C266_03618
symbol: flgI-2
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring biosynthesis protein FlgA; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: C266_03623
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: C266_03643
symbol: C266_03643
gene_biotype: protein_coding
description:
  Putative basal-body rod modification protein LfgD; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: C266_03678
symbol: C266_03678
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor for flagellar operon; COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: C266_03698
symbol: C266_03698
gene_biotype: protein_coding
description:
  Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: C266_03723
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: C266_03733
symbol: C266_03733
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: C266_03773
symbol: C266_03773
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_03783
symbol: C266_03783
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactonase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: C266_03788
symbol: C266_03788
gene_biotype: protein_coding
description:
  4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


ensembl_gene_id: C266_03833
symbol: C266_03833
gene_biotype: protein_coding
description:
  P-hydroxycinnamoyl CoA hydratase/lyase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: C266_03883
symbol: C266_03883
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_03888
symbol: C266_03888
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_03893
symbol: C266_03893
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: C266_03898
symbol: C266_03898
gene_biotype: protein_coding
description:
  COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_03903
symbol: C266_03903
gene_biotype: protein_coding
description:
  COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_03923
symbol: C266_03923
gene_biotype: protein_coding
description:
  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: C266_03963
symbol: C266_03963
gene_biotype: protein_coding
description:
  DL-methionine transporter subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.


ensembl_gene_id: C266_03968
symbol: C266_03968
gene_biotype: protein_coding
description:
  COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: C266_04249
symbol: C266_04249
gene_biotype: protein_coding
description:
  Two-component system NtrC family nitrogen regulation sensor histidine kinase GlnL; COG3852 Signal transduction histidine kinase, nitrogen specific.


ensembl_gene_id: C266_04254
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen metabolism transcriptional regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: C266_04259
symbol: C266_04259
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: C266_04324
symbol: C266_04324
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_04329
symbol: C266_04329
gene_biotype: protein_coding
description:
  2,4-diketo-3-deoxy-L-fuconate hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_04334
symbol: C266_04334
gene_biotype: protein_coding
description:
  3-ketoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_04349
symbol: C266_04349
gene_biotype: protein_coding
description:
  Ribosomal small subunit pseudouridine synthase A; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: C266_04354
symbol: C266_04354
gene_biotype: protein_coding
description:
  Nitrate/sulfonate/bicarbonate ABC transporter inner membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_04374
symbol: C266_04374
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase AhpD core; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: C266_04389
symbol: C266_04389
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_04394
symbol: C266_04394
gene_biotype: protein_coding
description:
  NodD transcription activator-like protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_04399
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: C266_04404
symbol: rlmB
gene_biotype: protein_coding
description:
  tRNA guanosine-2'-o-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: C266_04409
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: C266_04414
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: C266_04424
symbol: C266_04424
gene_biotype: protein_coding
description:
  Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: C266_04429
symbol: argA
gene_biotype: protein_coding
description:
  N-acetylglutamate synthase; COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: C266_04454
symbol: C266_04454
gene_biotype: protein_coding
description:
  Putative competence-damage protein; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA.


ensembl_gene_id: C266_04459
symbol: C266_04459
gene_biotype: protein_coding
description:
  Molecular chaperone GroES; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: C266_04472
symbol: C266_04472
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin family outer membrane protein associated with VreARI signaling system; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: C266_04482
symbol: C266_04482
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: C266_04517
symbol: C266_04517
gene_biotype: protein_coding
description:
  Outer membrane autotransporter barrel domain-containing protein 8; COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain.


ensembl_gene_id: C266_04724
symbol: C266_04724
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: C266_04764
symbol: C266_04764
gene_biotype: protein_coding
description:
  rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.


ensembl_gene_id: C266_04779
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: C266_04789
symbol: C266_04789
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0767 ABC-type transport system involved in resistance to organic solvents, permease component.


ensembl_gene_id: C266_04799
symbol: C266_04799
gene_biotype: protein_coding
description:
  Mce-like protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: C266_04834
symbol: C266_04834
gene_biotype: protein_coding
description:
  D-amino-acid transaminase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: C266_04844
symbol: C266_04844
gene_biotype: protein_coding
description:
  DNA-binding transcriptional activator GcvA; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_04859
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: C266_04864
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: C266_04884
symbol: C266_04884
gene_biotype: protein_coding
description:
  ABC transporter inner membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_04889
symbol: C266_04889
gene_biotype: protein_coding
description:
  Sulfonate/nitrate/taurine transport system ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: C266_04894
symbol: dctA
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: C266_04899
symbol: C266_04899
gene_biotype: protein_coding
description:
  Histidine kinase; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.


ensembl_gene_id: C266_04954
symbol: C266_04954
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: C266_04959
symbol: gshB
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: C266_04974
symbol: C266_04974
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: C266_04979
symbol: C266_04979
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: C266_04989
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: C266_04999
symbol: C266_04999
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: C266_05004
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: C266_05009
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: C266_05014
symbol: C266_05014
gene_biotype: protein_coding
description:
  Appr-1-p processing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: C266_05019
symbol: trmL
gene_biotype: protein_coding
description:
  RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: C266_05029
symbol: bioC
gene_biotype: protein_coding
description:
  Type 11 methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: C266_05044
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: C266_05054
symbol: C266_05054
gene_biotype: protein_coding
description:
  Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; COG0078 Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: C266_05069
symbol: C266_05069
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: C266_05084
symbol: C266_05084
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: C266_05089
symbol: C266_05089
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: C266_05124
symbol: C266_05124
gene_biotype: protein_coding
description:
  Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly.


ensembl_gene_id: C266_05129
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: C266_05134
symbol: C266_05134
gene_biotype: protein_coding
description:
  COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: C266_05159
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: C266_05184
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: C266_05204
symbol: nodI
gene_biotype: protein_coding
description:
  Nodulation ABC transporter NodI; Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4- linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system.


ensembl_gene_id: C266_05214
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: C266_05224
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: C266_05229
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: C266_05234
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: C266_05239
symbol: ipk
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: C266_05244
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: C266_05254
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: C266_05274
symbol: hprK
gene_biotype: protein_coding
description:
  HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).


ensembl_gene_id: C266_05279
symbol: C266_05279
gene_biotype: protein_coding
description:
  PTS IIA-like nitrogen-regulatory protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: C266_05284
symbol: C266_05284
gene_biotype: protein_coding
description:
  Sigma 54 modulation protein/ribosomal protein S30EA; COG1544 Ribosome-associated protein Y (PSrp-1).


ensembl_gene_id: C266_05289
symbol: C266_05289
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: C266_05294
symbol: C266_05294
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component.


ensembl_gene_id: C266_05299
symbol: lptA
gene_biotype: protein_coding
description:
  Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.


ensembl_gene_id: C266_05314
symbol: C266_05314
gene_biotype: protein_coding
description:
  KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: C266_05319
symbol: C266_05319
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: C266_05324
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: C266_05339
symbol: phnC
gene_biotype: protein_coding
description:
  Phosphonate/organophosphate ester transporter subunit; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: C266_05359
symbol: C266_05359
gene_biotype: protein_coding
description:
  Phosphonate C-P lyase system protein PhnL; COG4778 ABC-type phosphonate transport system, ATPase component.


ensembl_gene_id: C266_05364
symbol: phnK
gene_biotype: protein_coding
description:
  Phosphonate C-P lyase system protein PhnK; COG4107 ABC-type phosphonate transport system, ATPase component.


ensembl_gene_id: C266_05369
symbol: C266_05369
gene_biotype: protein_coding
description:
  Carbon-phosphorus lyase complex subunit PhnJ; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.


ensembl_gene_id: C266_05374
symbol: C266_05374
gene_biotype: protein_coding
description:
  Carbon-phosphorus lyase complex subunit PhnI; COG3626 Uncharacterized enzyme of phosphonate metabolism.


ensembl_gene_id: C266_05384
symbol: C266_05384
gene_biotype: protein_coding
description:
  Phosphonate C-P lyase system protein PhnG; COG3624 Uncharacterized enzyme of phosphonate metabolism.


ensembl_gene_id: C266_05399
symbol: phnN
gene_biotype: protein_coding
description:
  Phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).


ensembl_gene_id: C266_05409
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: C266_05414
symbol: C266_05414
gene_biotype: protein_coding
description:
  EmrB/QacA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_05429
symbol: phnW
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.


ensembl_gene_id: C266_05444
symbol: C266_05444
gene_biotype: protein_coding
description:
  DeoR family transcriptional regulator; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: C266_05484
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: C266_05494
symbol: C266_05494
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: C266_05504
symbol: C266_05504
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: C266_05509
symbol: C266_05509
gene_biotype: protein_coding
description:
  RND family efflux transporter MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_05519
symbol: C266_05519
gene_biotype: protein_coding
description:
  Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.


ensembl_gene_id: C266_05524
symbol: C266_05524
gene_biotype: protein_coding
description:
  Winged helix family two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_05544
symbol: C266_05544
gene_biotype: protein_coding
description:
  2-hydroxymuconic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: C266_05549
symbol: C266_05549
gene_biotype: protein_coding
description:
  Aspartate aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: C266_05599
symbol: C266_05599
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein 8; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: C266_05604
symbol: C266_05604
gene_biotype: protein_coding
description:
  Class II aldolase and adducin N-terminal domain-containing protein 3; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: C266_05634
symbol: ku
gene_biotype: protein_coding
description:
  Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: C266_05644
symbol: C266_05644
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: C266_05654
symbol: C266_05654
gene_biotype: protein_coding
description:
  Salicylate hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_05664
symbol: C266_05664
gene_biotype: protein_coding
description:
  Fumarylpyruvate hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_05679
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: C266_05704
symbol: C266_05704
gene_biotype: protein_coding
description:
  ABC transporter; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_05709
symbol: C266_05709
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_05719
symbol: C266_05719
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component family protein 33; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_05724
symbol: C266_05724
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component family protein 34; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_05729
symbol: C266_05729
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein, family 5 middle family protein 16; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: C266_05734
symbol: C266_05734
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein 9; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: C266_05739
symbol: C266_05739
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase family protein 4; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: C266_05759
symbol: C266_05759
gene_biotype: protein_coding
description:
  Glutamate/aspartate ABC transporter periplasmic binding subunit; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_05764
symbol: C266_05764
gene_biotype: protein_coding
description:
  Amino-acid ABC transporter protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: C266_05769
symbol: C266_05769
gene_biotype: protein_coding
description:
  Glutamate/aspartate ABC transporter membrane component; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: C266_05774
symbol: C266_05774
gene_biotype: protein_coding
description:
  COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: C266_05819
symbol: C266_05819
gene_biotype: protein_coding
description:
  Substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_05889
symbol: mhpB
gene_biotype: protein_coding
description:
  3-(2,3-dihydroxyphenyl)propionate dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.


ensembl_gene_id: C266_05894
symbol: mhpA
gene_biotype: protein_coding
description:
  3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI).


ensembl_gene_id: C266_05929
symbol: C266_05929
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: C266_06009
symbol: C266_06009
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: C266_06029
symbol: C266_06029
gene_biotype: protein_coding
description:
  Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.


ensembl_gene_id: C266_06064
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: C266_06069
symbol: C266_06069
gene_biotype: protein_coding
description:
  Beta-ketoadipyl CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: C266_06094
symbol: C266_06094
gene_biotype: protein_coding
description:
  FAD-dependent oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_06139
symbol: opgG
gene_biotype: protein_coding
description:
  Glucan biosynthesis protein G; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: C266_06144
symbol: C266_06144
gene_biotype: protein_coding
description:
  beta-D-glucoside glucohydrolase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: C266_06159
symbol: C266_06159
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: C266_06169
symbol: C266_06169
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATPase subunit; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_06209
symbol: C266_06209
gene_biotype: protein_coding
description:
  Gyoxylate/hydroxypyruvate reductase A; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: C266_06214
symbol: C266_06214
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: C266_06244
symbol: C266_06244
gene_biotype: protein_coding
description:
  NtaA/SnaA/SoxA family monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: C266_06249
symbol: C266_06249
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, aliphatic sulfonates; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_06299
symbol: C266_06299
gene_biotype: protein_coding
description:
  Cobaltochelatase; COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase); overlaps another CDS with the same product name.


ensembl_gene_id: C266_06309
symbol: C266_06309
gene_biotype: protein_coding
description:
  Sulfoacetaldehyde acetyltransferase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: C266_06329
symbol: C266_06329
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_06334
symbol: tauB
gene_biotype: protein_coding
description:
  ABC transporter-like protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: C266_06394
symbol: C266_06394
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: C266_06409
symbol: C266_06409
gene_biotype: protein_coding
description:
  Peptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: C266_06414
symbol: C266_06414
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: C266_06454
symbol: C266_06454
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter drug:H+ antiporter 2; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_06499
symbol: queF-2
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: C266_06509
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: C266_06524
symbol: C266_06524
gene_biotype: protein_coding
description:
  Isoquinoline 1-oxidoreductase subunit beta; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: C266_06529
symbol: C266_06529
gene_biotype: protein_coding
description:
  Isoquinoline 1-oxidoreductase subunit alpha; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: C266_06539
symbol: C266_06539
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: C266_06544
symbol: C266_06544
gene_biotype: protein_coding
description:
  HIT domain-containing protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: C266_06554
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: C266_06559
symbol: C266_06559
gene_biotype: protein_coding
description:
  Import inner membrane translocase subunit Tim44; COG4395 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: C266_06569
symbol: ubiB
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: C266_06594
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: C266_06599
symbol: nudB
gene_biotype: protein_coding
description:
  Dihydroneopterin triphosphate pyrophosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: C266_06604
symbol: clsB
gene_biotype: protein_coding
description:
  Phospholipase D; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: C266_06639
symbol: C266_06639
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components.


ensembl_gene_id: C266_06649
symbol: C266_06649
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: C266_06654
symbol: C266_06654
gene_biotype: protein_coding
description:
  Glutamate/aspartate ABC transporter periplasmic glutamate/aspartate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_06664
symbol: C266_06664
gene_biotype: protein_coding
description:
  Glutamate/aspartate transmembrane ABC transporter protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: C266_06669
symbol: C266_06669
gene_biotype: protein_coding
description:
  Glutamate Aspartate transport ATP-binding protein GltL; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: C266_06694
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: C266_06704
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: C266_06724
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: C266_06734
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: C266_06739
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: C266_06749
symbol: C266_06749
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: C266_06759
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: C266_06764
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: C266_06779
symbol: C266_06779
gene_biotype: protein_coding
description:
  2-ketogluconate 6-phosphate reductase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: C266_06799
symbol: C266_06799
gene_biotype: protein_coding
description:
  High-affinity gluconate transporter (GNT-III system) transmembrane protein; COG2610 H+/gluconate symporter and related permeases.


ensembl_gene_id: C266_06809
symbol: C266_06809
gene_biotype: protein_coding
description:
  RNA methylase; COG0116 Predicted N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily.


ensembl_gene_id: C266_06819
symbol: C266_06819
gene_biotype: protein_coding
description:
  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: C266_06824
symbol: C266_06824
gene_biotype: protein_coding
description:
  NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: C266_06834
symbol: C266_06834
gene_biotype: protein_coding
description:
  Alanine dehydrogenase/PNT domain-containing protein; COG3288 NAD/NADP transhydrogenase alpha subunit.


ensembl_gene_id: C266_06856
symbol: ubiG
gene_biotype: protein_coding
description:
  Bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: C266_06866
symbol: C266_06866
gene_biotype: protein_coding
description:
  COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: C266_06996
symbol: ycgR
gene_biotype: protein_coding
description:
  YcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: C266_07096
symbol: C266_07096
gene_biotype: protein_coding
description:
  Putative positive effector of YfiN activity, OM lipoprotein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: C266_07111
symbol: C266_07111
gene_biotype: protein_coding
description:
  PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: C266_07116
symbol: C266_07116
gene_biotype: protein_coding
description:
  COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: C266_07131
symbol: C266_07131
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: C266_07141
symbol: C266_07141
gene_biotype: protein_coding
description:
  NAD(P)h dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: C266_07146
symbol: C266_07146
gene_biotype: protein_coding
description:
  Potassium efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: C266_07186
symbol: C266_07186
gene_biotype: protein_coding
description:
  COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family.


ensembl_gene_id: C266_07216
symbol: C266_07216
gene_biotype: protein_coding
description:
  N-hydroxyarylamine O-acetyltransferase; COG2162 Arylamine N-acetyltransferase; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: C266_07246
symbol: C266_07246
gene_biotype: protein_coding
description:
  Putative short-chain type dehydrogenase/reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_07276
symbol: C266_07276
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; COG0820 Predicted Fe-S-cluster redox enzyme; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: C266_07291
symbol: C266_07291
gene_biotype: protein_coding
description:
  Aldolase II superfamily protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: C266_07312
symbol: C266_07312
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: C266_07317
symbol: C266_07317
gene_biotype: protein_coding
description:
  Voltage-gated potassium channel; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: C266_07322
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: C266_07332
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: C266_07337
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: C266_07342
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: C266_07347
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: C266_07357
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: C266_07362
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: C266_07372
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: C266_07382
symbol: C266_07382
gene_biotype: protein_coding
description:
  Protease Do; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: C266_07402
symbol: C266_07402
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: C266_07412
symbol: C266_07412
gene_biotype: protein_coding
description:
  3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: C266_07422
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: C266_07427
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: C266_07442
symbol: C266_07442
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: C266_07457
symbol: C266_07457
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: C266_07467
symbol: C266_07467
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: C266_07472
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: C266_07477
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: C266_07487
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: C266_07492
symbol: C266_07492
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: C266_07502
symbol: C266_07502
gene_biotype: protein_coding
description:
  Acetyltransferase, GnaT family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: C266_07512
symbol: C266_07512
gene_biotype: protein_coding
description:
  Glyoxylate reductase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: C266_07527
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: C266_07532
symbol: C266_07532
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: C266_07560
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: C266_07565
symbol: C266_07565
gene_biotype: protein_coding
description:
  Two-component system OmpR family phosphate regulon sensor histidine kinase PhoR; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: C266_07570
symbol: C266_07570
gene_biotype: protein_coding
description:
  Phosphate regulon transcriptional regulatory protein PhoB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_07580
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: C266_07585
symbol: pstA
gene_biotype: protein_coding
description:
  Phosphate transporter permease subunit PtsA; COG0581 ABC-type phosphate transport system, permease component.


ensembl_gene_id: C266_07590
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate transporter permease subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: C266_07595
symbol: C266_07595
gene_biotype: protein_coding
description:
  Phosphate ABC transporter substrate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: C266_07600
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: C266_07610
symbol: ftsH
gene_biotype: protein_coding
description:
  Protease, ATP-dependent zinc-metallo; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: C266_07615
symbol: rrmJ
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: C266_07630
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: C266_07655
symbol: C266_07655
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter DctA; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: C266_07675
symbol: C266_07675
gene_biotype: protein_coding
description:
  Putative dicarboxylic acid hydrolase; COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: C266_07690
symbol: C266_07690
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: C266_07715
symbol: C266_07715
gene_biotype: protein_coding
description:
  4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: C266_07720
symbol: C266_07720
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: C266_07725
symbol: pagP
gene_biotype: protein_coding
description:
  Phospholipid:lipid A palmitoyltransferase; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.


ensembl_gene_id: C266_07740
symbol: C266_07740
gene_biotype: protein_coding
description:
  COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: C266_07745
symbol: C266_07745
gene_biotype: protein_coding
description:
  Family 3 extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_07775
symbol: C266_07775
gene_biotype: protein_coding
description:
  2OG-Fe(II) oxygenase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: C266_07805
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: C266_07820
symbol: C266_07820
gene_biotype: protein_coding
description:
  Toluene transport system Ttg2D protein; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.


ensembl_gene_id: C266_07825
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: C266_07895
symbol: C266_07895
gene_biotype: protein_coding
description:
  Transmembrane cytochrome O ubiquinol oxidase (subunit III) oxidoreductase; COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3.


ensembl_gene_id: C266_07930
symbol: macB
gene_biotype: protein_coding
description:
  Macrolide-specific ABC-type efflux carrier; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: C266_07935
symbol: C266_07935
gene_biotype: protein_coding
description:
  Macrolide-specific efflux protein macA; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_07955
symbol: C266_07955
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin family outer membrane protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: C266_07990
symbol: C266_07990
gene_biotype: protein_coding
description:
  Aldolase domain-containing protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: C266_07995
symbol: pdxA-2
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family.


ensembl_gene_id: C266_08005
symbol: kdgT
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family.


ensembl_gene_id: C266_08030
symbol: C266_08030
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: C266_08040
symbol: C266_08040
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, GntR family protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: C266_08050
symbol: C266_08050
gene_biotype: protein_coding
description:
  Sigma54 specific transcriptional regulator, Fis family protein; COG3284 Transcriptional activator of acetoin/glycerol metabolism.


ensembl_gene_id: C266_08095
symbol: C266_08095
gene_biotype: protein_coding
description:
  UbiD family decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: C266_08100
symbol: ubiX
gene_biotype: protein_coding
description:
  Putative aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: C266_08105
symbol: C266_08105
gene_biotype: protein_coding
description:
  ABC transporter, inner membrane subunit; COG4120 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_08115
symbol: C266_08115
gene_biotype: protein_coding
description:
  ABC transporter periplasmic ligand-binding protein; COG2984 ABC-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: C266_08125
symbol: C266_08125
gene_biotype: protein_coding
description:
  Putative acetolactate synthase large subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: C266_08135
symbol: C266_08135
gene_biotype: protein_coding
description:
  5-oxoprolinase (ATP-hydrolyzing); COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit; overlaps another CDS with the same product name.


ensembl_gene_id: C266_08140
symbol: C266_08140
gene_biotype: protein_coding
description:
  5-oxoprolinase (ATP-hydrolyzing); COG0145 N-methylhydantoinase A/acetone carboxylase, beta subunit; overlaps another CDS with the same product name.


ensembl_gene_id: C266_08145
symbol: C266_08145
gene_biotype: protein_coding
description:
  ABC transporter, periplasmic ligand binding protein; COG2984 ABC-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: C266_08165
symbol: C266_08165
gene_biotype: protein_coding
description:
  Betaine aldehyde dehydrogenase (BADH) protein; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: C266_08170
symbol: C266_08170
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_08175
symbol: C266_08175
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_08180
symbol: C266_08180
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: C266_08190
symbol: C266_08190
gene_biotype: protein_coding
description:
  Translation-inhibition endoribonuclease; COG0251 Putative translation initiation inhibitor, yjgF family.


ensembl_gene_id: C266_08275
symbol: C266_08275
gene_biotype: protein_coding
description:
  Electron transferring flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: C266_08280
symbol: C266_08280
gene_biotype: protein_coding
description:
  Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: C266_08325
symbol: C266_08325
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_08340
symbol: C266_08340
gene_biotype: protein_coding
description:
  Allophanate hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: C266_08350
symbol: C266_08350
gene_biotype: protein_coding
description:
  Sulfonate ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_08355
symbol: C266_08355
gene_biotype: protein_coding
description:
  Putative aliphatic sulfonate ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: C266_08375
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: C266_08380
symbol: C266_08380
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: C266_08385
symbol: lolA
gene_biotype: protein_coding
description:
  Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: C266_08415
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: C266_08425
symbol: C266_08425
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: C266_08435
symbol: C266_08435
gene_biotype: protein_coding
description:
  Pyridoxal phosphate enzyme, YggS family protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: C266_08450
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: C266_08470
symbol: C266_08470
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: C266_08475
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: C266_08495
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_08510
symbol: C266_08510
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.


ensembl_gene_id: C266_08520
symbol: C266_08520
gene_biotype: protein_coding
description:
  Bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; COG2959 Uncharacterized enzyme of heme biosynthesis; overlaps another CDS with the same product name.


ensembl_gene_id: C266_08525
symbol: C266_08525
gene_biotype: protein_coding
description:
  Bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: C266_08530
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: C266_08535
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: C266_08550
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symport carrier protein GltS; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: C266_08565
symbol: C266_08565
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: C266_08575
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: C266_08610
symbol: C266_08610
gene_biotype: protein_coding
description:
  Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: C266_08615
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: C266_08620
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: C266_08630
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: C266_08635
symbol: C266_08635
gene_biotype: protein_coding
description:
  Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: C266_08640
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: C266_08645
symbol: C266_08645
gene_biotype: protein_coding
description:
  Threonine-phosphate decarboxylase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: C266_08665
symbol: C266_08665
gene_biotype: protein_coding
description:
  Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: C266_08675
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: C266_08680
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: C266_08685
symbol: C266_08685
gene_biotype: protein_coding
description:
  cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: C266_08690
symbol: C266_08690
gene_biotype: protein_coding
description:
  ABC Fe3+-hydroxamate/cobalamin transporter, ATPase subunit; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: C266_08695
symbol: C266_08695
gene_biotype: protein_coding
description:
  Vitamin B12 ABC transporter membrane protein BtuC; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: C266_08710
symbol: C266_08710
gene_biotype: protein_coding
description:
  Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: C266_08737
symbol: C266_08737
gene_biotype: protein_coding
description:
  Class V aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: C266_08747
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: C266_08812
symbol: C266_08812
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: C266_08822
symbol: C266_08822
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2514 Predicted ring-cleavage extradiol dioxygenase.


ensembl_gene_id: C266_08837
symbol: C266_08837
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: C266_08847
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: C266_08852
symbol: glmU
gene_biotype: protein_coding
description:
  Bifunctional UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: C266_08857
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: C266_08892
symbol: cca
gene_biotype: protein_coding
description:
  2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: C266_08907
symbol: C266_08907
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: C266_08912
symbol: C266_08912
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: C266_08927
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: C266_08932
symbol: C266_08932
gene_biotype: protein_coding
description:
  Omega amino acid--pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: C266_08962
symbol: C266_08962
gene_biotype: protein_coding
description:
  Urea ABC transporter permease; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_08967
symbol: C266_08967
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_08972
symbol: C266_08972
gene_biotype: protein_coding
description:
  Urea ABC transporter ATP-binding protein UrtD; COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: C266_08977
symbol: C266_08977
gene_biotype: protein_coding
description:
  Urea ABC transporter ATP-binding protein UrtE; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_08982
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: C266_08997
symbol: C266_08997
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: C266_09012
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: C266_09022
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: C266_09032
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: C266_09037
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: C266_09042
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: C266_09052
symbol: dppF
gene_biotype: protein_coding
description:
  Dipeptide transporter ATP-binding subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_09067
symbol: C266_09067
gene_biotype: protein_coding
description:
  Alkaline phosphatase; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_09077
symbol: C266_09077
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: C266_09092
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: C266_09132
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: C266_09182
symbol: C266_09182
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_09187
symbol: C266_09187
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_09192
symbol: C266_09192
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_09197
symbol: C266_09197
gene_biotype: protein_coding
description:
  Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: C266_09222
symbol: C266_09222
gene_biotype: protein_coding
description:
  Vanillate O-demethylase oxygenase; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: C266_09242
symbol: C266_09242
gene_biotype: protein_coding
description:
  Benzoylformate decarboxylase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: C266_09257
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: C266_09277
symbol: C266_09277
gene_biotype: protein_coding
description:
  Fis family two component transcriptional regulator; COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain.


ensembl_gene_id: C266_09282
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: C266_09287
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: C266_09302
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: C266_09312
symbol: C266_09312
gene_biotype: protein_coding
description:
  Transcription regulator protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: C266_09327
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: C266_09337
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: C266_09347
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: C266_09367
symbol: C266_09367
gene_biotype: protein_coding
description:
  Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: C266_09407
symbol: C266_09407
gene_biotype: protein_coding
description:
  Multidrug transporter rnd family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: C266_09412
symbol: C266_09412
gene_biotype: protein_coding
description:
  Secretion protein HlyD; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_09422
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: C266_09432
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: C266_09437
symbol: gatC
gene_biotype: protein_coding
description:
  asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: C266_09457
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: C266_09462
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: C266_09487
symbol: queE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: C266_09492
symbol: queC
gene_biotype: protein_coding
description:
  exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: C266_09497
symbol: C266_09497
gene_biotype: protein_coding
description:
  Fis family two component transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: C266_09502
symbol: C266_09502
gene_biotype: protein_coding
description:
  Nitrogen regulation protein ntrY; COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.


ensembl_gene_id: C266_09512
symbol: C266_09512
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: C266_09517
symbol: htpX
gene_biotype: protein_coding
description:
  M48 family peptidase; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: C266_09522
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: C266_09527
symbol: C266_09527
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: C266_09572
symbol: C266_09572
gene_biotype: protein_coding
description:
  Transmembrane sensor histidine kinase transcription regulator protein; COG4564 Signal transduction histidine kinase.


ensembl_gene_id: C266_09582
symbol: C266_09582
gene_biotype: protein_coding
description:
  PilT domain-containing protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.


ensembl_gene_id: C266_09592
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: C266_09597
symbol: C266_09597
gene_biotype: protein_coding
description:
  Glyoxylate reductase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: C266_09607
symbol: C266_09607
gene_biotype: protein_coding
description:
  Thioesterase family protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: C266_09629
symbol: C266_09629
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase (Alpha subunit part 1) oxidoreductase protein; COG3288 NAD/NADP transhydrogenase alpha subunit.


ensembl_gene_id: C266_09634
symbol: nudJ
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: C266_09639
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: C266_09714
symbol: C266_09714
gene_biotype: protein_coding
description:
  Two component system sensor kinase SsrB; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: C266_09769
symbol: C266_09769
gene_biotype: protein_coding
description:
  Peptidoglycan N-acetylmuramoylhydrolase; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: C266_09834
symbol: C266_09834
gene_biotype: protein_coding
description:
  Type II and III secretion system protein; COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: C266_09879
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: C266_09884
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: C266_09889
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: C266_09894
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to fo [...]


ensembl_gene_id: C266_09899
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: C266_09904
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: C266_09909
symbol: C266_09909
gene_biotype: protein_coding
description:
  LysR family hydrogen peroxide-inducible genes activator; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_09929
symbol: C266_09929
gene_biotype: protein_coding
description:
  GlcG protein; COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol.


ensembl_gene_id: C266_09984
symbol: C266_09984
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: C266_09999
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: C266_10084
symbol: C266_10084
gene_biotype: protein_coding
description:
  GntR family regulatory protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: C266_10089
symbol: C266_10089
gene_biotype: protein_coding
description:
  hydroxymethylglutaryl-CoA reductase, degradative; COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.


ensembl_gene_id: C266_10114
symbol: C266_10114
gene_biotype: protein_coding
description:
  Lysophospholipase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: C266_10134
symbol: C266_10134
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: C266_10159
symbol: C266_10159
gene_biotype: protein_coding
description:
  5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_10199
symbol: C266_10199
gene_biotype: protein_coding
description:
  Putative aliphatic sulfonates transport systempermease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_10204
symbol: C266_10204
gene_biotype: protein_coding
description:
  Putative periplasmic-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_10289
symbol: C266_10289
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur-binding domain-containing protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: C266_10374
symbol: C266_10374
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.


ensembl_gene_id: C266_10466
symbol: C266_10466
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_10471
symbol: C266_10471
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_10496
symbol: C266_10496
gene_biotype: protein_coding
description:
  Aminocarboxymuconate-semialdehyde decarboxylase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: C266_10501
symbol: nbaC
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.


ensembl_gene_id: C266_10526
symbol: C266_10526
gene_biotype: protein_coding
description:
  ABC transporter periplasmic substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: C266_10531
symbol: C266_10531
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0555 ABC-type sulfate transport system, permease component.


ensembl_gene_id: C266_10536
symbol: C266_10536
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: C266_10541
symbol: C266_10541
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_10546
symbol: cpdA-2
gene_biotype: protein_coding
description:
  cAMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: C266_10551
symbol: C266_10551
gene_biotype: protein_coding
description:
  Globin:oxidoreductase FAD/NAD(P)-binding:oxidoreductase FAD-binding region; COG1017 Hemoglobin-like flavoprotein; Belongs to the globin family.


ensembl_gene_id: C266_10601
symbol: C266_10601
gene_biotype: protein_coding
description:
  Putative pilin glycosylation protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: C266_10611
symbol: C266_10611
gene_biotype: protein_coding
description:
  TDP-4-oxo-6-deoxy-D-glucose transaminase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: C266_10616
symbol: cysC
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1 / adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: C266_10636
symbol: C266_10636
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: C266_10671
symbol: C266_10671
gene_biotype: protein_coding
description:
  Transcriptional activator MetR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_10676
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: C266_10696
symbol: C266_10696
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: C266_10706
symbol: C266_10706
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: C266_10731
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: C266_10736
symbol: C266_10736
gene_biotype: protein_coding
description:
  Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: C266_10751
symbol: C266_10751
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: C266_10756
symbol: ribB-2
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: C266_10811
symbol: mntH-2
gene_biotype: protein_coding
description:
  Manganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: C266_10826
symbol: dnaE2
gene_biotype: protein_coding
description:
  DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: C266_10841
symbol: C266_10841
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: C266_10851
symbol: C266_10851
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_10881
symbol: C266_10881
gene_biotype: protein_coding
description:
  Aliphatic sulfonate ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_10956
symbol: C266_10956
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein, C-terminal; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_10976
symbol: C266_10976
gene_biotype: protein_coding
description:
  ApbE-like lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: C266_10981
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: C266_10996
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: C266_11001
symbol: C266_11001
gene_biotype: protein_coding
description:
  Lytic transglycosylase, catalytic; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: C266_11026
symbol: C266_11026
gene_biotype: protein_coding
description:
  EmrB/QacA family drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_11036
symbol: C266_11036
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: C266_11051
symbol: C266_11051
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin family N-terminal domain protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: C266_11066
symbol: C266_11066
gene_biotype: protein_coding
description:
  HlyB-like activation/secretion signal peptide protein; COG2831 Hemolysin activation/secretion protein.


ensembl_gene_id: C266_11076
symbol: C266_11076
gene_biotype: protein_coding
description:
  salicylyl-CoA 5-hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_11081
symbol: C266_11081
gene_biotype: protein_coding
description:
  Short-chain dehydrogenases/reductases (sdr) family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_11111
symbol: allA
gene_biotype: protein_coding
description:
  Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.


ensembl_gene_id: C266_11140
symbol: C266_11140
gene_biotype: protein_coding
description:
  Resolvase domain-containing protein; COG1961 Site-specific recombinases, DNA invertase Pin homologs.


ensembl_gene_id: C266_11240
symbol: C266_11240
gene_biotype: protein_coding
description:
  Prophage repressor; COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Belongs to the peptidase S24 family.


ensembl_gene_id: C266_11335
symbol: C266_11335
gene_biotype: protein_coding
description:
  COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: C266_11410
symbol: C266_11410
gene_biotype: protein_coding
description:
  BFD/(2Fe-2S)-binding domain-containing protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: C266_11420
symbol: C266_11420
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: C266_11440
symbol: C266_11440
gene_biotype: protein_coding
description:
  Putative stress-induced protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: C266_11515
symbol: C266_11515
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: C266_11525
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: C266_11530
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: C266_11535
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: C266_11540
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: C266_11550
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: C266_11555
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: C266_11560
symbol: C266_11560
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase I SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: C266_11575
symbol: C266_11575
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: C266_11600
symbol: C266_11600
gene_biotype: protein_coding
description:
  Tripartite ATP-independent periplasmic transporter dctp component; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: C266_11610
symbol: C266_11610
gene_biotype: protein_coding
description:
  Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: C266_11620
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: C266_11625
symbol: C266_11625
gene_biotype: protein_coding
description:
  1-acylglycerol-3-phosphate O-acyltransferase; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_11705
symbol: gudD
gene_biotype: protein_coding
description:
  Glucarate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: C266_11710
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: C266_11715
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: C266_11730
symbol: leuA-2
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: C266_11740
symbol: C266_11740
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: C266_11745
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: C266_11750
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: C266_11760
symbol: C266_11760
gene_biotype: protein_coding
description:
  Acetolactate synthase 3 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: C266_11785
symbol: C266_11785
gene_biotype: protein_coding
description:
  PGAP1 family protein; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: C266_11815
symbol: C266_11815
gene_biotype: protein_coding
description:
  6-aminohexanoate-cyclic-dimer hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: C266_11910
symbol: C266_11910
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase oxidoreductase; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: C266_11955
symbol: C266_11955
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding component (tauB-like) protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: C266_11965
symbol: C266_11965
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding component; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_12000
symbol: C266_12000
gene_biotype: protein_coding
description:
  ABC transporter amino acid-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_12075
symbol: C266_12075
gene_biotype: protein_coding
description:
  Oxidoreductase FAD/NAD(P)-binding subunit; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: C266_12125
symbol: C266_12125
gene_biotype: protein_coding
description:
  Ring-opening amidohydrolase; Cyclic amide hydrolase of unknown substrate specificity. Catalyzes the hydrolytic ring-opening of a cyclic amide. Does not act on cyanuric acid nor barbituric acid.


ensembl_gene_id: C266_12130
symbol: C266_12130
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_12135
symbol: C266_12135
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_12140
symbol: C266_12140
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: C266_12180
symbol: C266_12180
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: C266_12220
symbol: C266_12220
gene_biotype: protein_coding
description:
  Type VI secretion system protein VasG; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: C266_12270
symbol: C266_12270
gene_biotype: protein_coding
description:
  Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: C266_12290
symbol: C266_12290
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine ABC transporter ATP-binding protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_12320
symbol: C266_12320
gene_biotype: protein_coding
description:
  Crp family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: C266_12335
symbol: C266_12335
gene_biotype: protein_coding
description:
  BFD (2Fe-2S)-binding domain-containing protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: C266_12360
symbol: C266_12360
gene_biotype: protein_coding
description:
  COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_12365
symbol: C266_12365
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding component; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: C266_12405
symbol: C266_12405
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: C266_12485
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: C266_12490
symbol: glpD
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: C266_12530
symbol: prpB
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: C266_12535
symbol: C266_12535
gene_biotype: protein_coding
description:
  Fis family proprionate catabolism activator; COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: C266_12545
symbol: C266_12545
gene_biotype: protein_coding
description:
  Drug resistance transporter Bcr/CflA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_12550
symbol: C266_12550
gene_biotype: protein_coding
description:
  Amino acid ABC transporter periplasmic ligand binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: C266_12580
symbol: C266_12580
gene_biotype: protein_coding
description:
  NAD binding domain of 6-phosphogluconate dehydrogenase family protein 4; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: C266_12625
symbol: C266_12625
gene_biotype: protein_coding
description:
  EAL domain-containing protein; COG4943 Predicted signal transduction protein containing sensor and EAL domains.


ensembl_gene_id: C266_12655
symbol: C266_12655
gene_biotype: protein_coding
description:
  Cache sensor-containing methyl-accepting chemotaxis sensory transducer; COG0840 Methyl-accepting chemotaxis protein.


ensembl_gene_id: C266_12695
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: C266_12705
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: C266_12720
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: C266_12735
symbol: C266_12735
gene_biotype: protein_coding
description:
  Geranyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: C266_12740
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: C266_12745
symbol: C266_12745
gene_biotype: protein_coding
description:
  Rieske family iron-sulfur cluster-binding protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: C266_12775
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: C266_12780
symbol: C266_12780
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: C266_12795
symbol: thrB
gene_biotype: protein_coding
description:
  COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: C266_12810
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: C266_12820
symbol: C266_12820
gene_biotype: protein_coding
description:
  SirA family protein; COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: C266_12835
symbol: C266_12835
gene_biotype: protein_coding
description:
  Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: C266_12855
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: C266_12910
symbol: C266_12910
gene_biotype: protein_coding
description:
  ABC superfamily ATP binding cassette transporter, membrane protein; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_12915
symbol: C266_12915
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components.


ensembl_gene_id: C266_12920
symbol: C266_12920
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: C266_12955
symbol: C266_12955
gene_biotype: protein_coding
description:
  6-aminohexanoate-cyclic-dimer hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: C266_13084
symbol: C266_13084
gene_biotype: protein_coding
description:
  Peptide transport system ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_13089
symbol: C266_13089
gene_biotype: protein_coding
description:
  Family 5 extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: C266_13094
symbol: C266_13094
gene_biotype: protein_coding
description:
  Glutathione ABC transporter permease GsiC; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_13099
symbol: C266_13099
gene_biotype: protein_coding
description:
  Glutathione ABC transporter permease GsiD; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_13134
symbol: C266_13134
gene_biotype: protein_coding
description:
  Sugar ABC transporter, ATP-binding protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_13139
symbol: C266_13139
gene_biotype: protein_coding
description:
  Extracellular solute-binding family protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: C266_13149
symbol: C266_13149
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component family protein 2; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: C266_13169
symbol: C266_13169
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: C266_13249
symbol: C266_13249
gene_biotype: protein_coding
description:
  Tungsten-containing formate dehydrogenase subunit beta; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_13254
symbol: C266_13254
gene_biotype: protein_coding
description:
  oxalyl-CoA decarboxylase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: C266_13259
symbol: frc
gene_biotype: protein_coding
description:
  Formyl-coenzyme A transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.


ensembl_gene_id: C266_13274
symbol: C266_13274
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_13334
symbol: C266_13334
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: C266_13364
symbol: C266_13364
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: C266_13379
symbol: C266_13379
gene_biotype: protein_coding
description:
  COG2995 Uncharacterized paraquat-inducible protein A; overlaps another CDS with the same product name.


ensembl_gene_id: C266_13394
symbol: C266_13394
gene_biotype: protein_coding
description:
  Formate dehydrogenase, major subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: C266_13409
symbol: fdhE
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: C266_13414
symbol: selA
gene_biotype: protein_coding
description:
  Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: C266_13459
symbol: C266_13459
gene_biotype: protein_coding
description:
  Proton glutamate symport protein; COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: C266_13469
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: C266_13494
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: C266_13499
symbol: C266_13499
gene_biotype: protein_coding
description:
  Nitrilotriacetate monooxygenase component b; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: C266_13514
symbol: C266_13514
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: C266_13534
symbol: C266_13534
gene_biotype: protein_coding
description:
  ABC branched-chain amino acid family transporter, inner membrane subunit; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_13569
symbol: C266_13569
gene_biotype: protein_coding
description:
  Cro/CI family transcriptional regulator -like protein; COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: C266_13589
symbol: C266_13589
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase.


ensembl_gene_id: C266_13604
symbol: C266_13604
gene_biotype: protein_coding
description:
  DSBA oxidoreductase; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: C266_13719
symbol: C266_13719
gene_biotype: protein_coding
description:
  DNA-binding protein; COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase).


ensembl_gene_id: C266_13739
symbol: C266_13739
gene_biotype: protein_coding
description:
  SPP1 family phage head morphogenesis protein; COG2369 Uncharacterized protein, homolog of phage Mu protein gp30.


ensembl_gene_id: C266_14202
symbol: C266_14202
gene_biotype: protein_coding
description:
  Glutamate/aspartate ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_14207
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: C266_14212
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: C266_14217
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: C266_14227
symbol: C266_14227
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_14242
symbol: C266_14242
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component.


ensembl_gene_id: C266_14262
symbol: C266_14262
gene_biotype: protein_coding
description:
  Threonyl/alanyl tRNA synthetase SAD; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.


ensembl_gene_id: C266_14287
symbol: C266_14287
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: C266_14322
symbol: C266_14322
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde-2,1-aminomutase; COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: C266_14327
symbol: C266_14327
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: C266_14422
symbol: C266_14422
gene_biotype: protein_coding
description:
  Methyltransferase type 11; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: C266_14442
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: C266_14472
symbol: C266_14472
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA ligase II; COG0180 Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: C266_14487
symbol: C266_14487
gene_biotype: protein_coding
description:
  TonB-dependent hemoglobin/transferrin/lactoferrin receptor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: C266_14497
symbol: C266_14497
gene_biotype: protein_coding
description:
  Iron ABC transporter substrate-binding protein; COG4558 ABC-type hemin transport system, periplasmic component.


ensembl_gene_id: C266_14502
symbol: C266_14502
gene_biotype: protein_coding
description:
  Hemin ABC transporter, permease protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: C266_14507
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin importer ATP-binding subunit; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: C266_14567
symbol: C266_14567
gene_biotype: protein_coding
description:
  Gamma-glutamyl:cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: C266_14577
symbol: mnmC
gene_biotype: protein_coding
description:
  Bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: C266_14612
symbol: C266_14612
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: C266_14632
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: C266_14637
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: C266_14642
symbol: C266_14642
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: C266_14647
symbol: C266_14647
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: C266_14657
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: C266_14662
symbol: C266_14662
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: C266_14667
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: C266_14807
symbol: C266_14807
gene_biotype: protein_coding
description:
  Putative aliphatic sulfonate family ABC transporter, periplasmic ligand-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_14837
symbol: C266_14837
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components; overlaps another CDS with the same product name.


ensembl_gene_id: C266_14842
symbol: C266_14842
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4177 ABC-type branched-chain amino acid transport system, permease component; overlaps another CDS with the same product name.


ensembl_gene_id: C266_14847
symbol: C266_14847
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport ATP-binding protein BRAF 6; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_14852
symbol: C266_14852
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_14857
symbol: C266_14857
gene_biotype: protein_coding
description:
  Amidase, hydantoinase/carbamoylase family protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: C266_14862
symbol: C266_14862
gene_biotype: protein_coding
description:
  Microcystin LR degradation protein MlrC-like protein; Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC); Belongs to the peptidase M81 family.


ensembl_gene_id: C266_14892
symbol: C266_14892
gene_biotype: protein_coding
description:
  Urea ABC transporter permease UrtC; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_14897
symbol: C266_14897
gene_biotype: protein_coding
description:
  Urea ABC transporter permease UrtB; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_14912
symbol: C266_14912
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_14952
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis-specific methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: C266_15087
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: C266_15137
symbol: uppP-2
gene_biotype: protein_coding
description:
  Putative undecaprenol kinase 2 (bacitracin resistance protein 2); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: C266_15177
symbol: C266_15177
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: C266_15187
symbol: ampC
gene_biotype: protein_coding
description:
  beta-lactamase/D-alanine carboxypeptidase; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: C266_15202
symbol: C266_15202
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily.


ensembl_gene_id: C266_15207
symbol: C266_15207
gene_biotype: protein_coding
description:
  Putative glutamine transport system ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: C266_15222
symbol: C266_15222
gene_biotype: protein_coding
description:
  Solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_15237
symbol: C266_15237
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2215 ABC-type uncharacterized transport system, permease component; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: C266_15267
symbol: C266_15267
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: C266_15292
symbol: C266_15292
gene_biotype: protein_coding
description:
  Inner-membrane translocator ABC transporter; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_15317
symbol: C266_15317
gene_biotype: protein_coding
description:
  Flavin reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: C266_15417
symbol: C266_15417
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: C266_15437
symbol: C266_15437
gene_biotype: protein_coding
description:
  ferredoxin--NAD(+) reductase FAD/NAD(P)-binding protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: C266_15462
symbol: C266_15462
gene_biotype: protein_coding
description:
  Flavin reductase-like, FMN-binding protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: C266_15467
symbol: C266_15467
gene_biotype: protein_coding
description:
  Putative monooxygenase subunit; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_15477
symbol: C266_15477
gene_biotype: protein_coding
description:
  Carbonate dehydratase; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_15482
symbol: C266_15482
gene_biotype: protein_coding
description:
  COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis.


ensembl_gene_id: C266_15497
symbol: C266_15497
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: C266_15562
symbol: C266_15562
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: C266_15594
symbol: C266_15594
gene_biotype: protein_coding
description:
  Peptidase dimerization domain-containing protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: C266_15599
symbol: C266_15599
gene_biotype: protein_coding
description:
  Amidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: C266_15609
symbol: C266_15609
gene_biotype: protein_coding
description:
  Oxidoreductase FAD-binding subunit; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: C266_15709
symbol: C266_15709
gene_biotype: protein_coding
description:
  Phospholipase D/Transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: C266_15729
symbol: def-3
gene_biotype: protein_coding
description:
  Aminotransferase, class IV; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: C266_15734
symbol: C266_15734
gene_biotype: protein_coding
description:
  Aminotransferase, class IV; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; overlaps another CDS with the same product name.


ensembl_gene_id: C266_15739
symbol: C266_15739
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes.


ensembl_gene_id: C266_15759
symbol: paaB
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase subunit PaaB; COG3460 Uncharacterized enzyme of phenylacetate metabolism.


ensembl_gene_id: C266_15769
symbol: C266_15769
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation protein PaaD; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.


ensembl_gene_id: C266_15774
symbol: C266_15774
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase/reductase subunit PaaK; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: C266_15794
symbol: C266_15794
gene_biotype: protein_coding
description:
  Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein; COG1522 Transcriptional regulators.


ensembl_gene_id: C266_15819
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: C266_15824
symbol: crcB
gene_biotype: protein_coding
description:
  CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: C266_15856
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: C266_15861
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: C266_15866
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: C266_15871
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: C266_15876
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: C266_15886
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: C266_15891
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: C266_15896
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: C266_15901
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: C266_15906
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: C266_15911
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: C266_15916
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.


ensembl_gene_id: C266_15921
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: C266_15926
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: C266_15931
symbol: mraZ
gene_biotype: protein_coding
description:
  Cell division protein MraZ; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: C266_15936
symbol: coq7
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein COQ7-like protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: C266_15956
symbol: C266_15956
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: C266_15975
symbol: srkA
gene_biotype: protein_coding
description:
  Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: C266_16025
symbol: C266_16025
gene_biotype: protein_coding
description:
  Alkylphosphonate utilization protein PhnA; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: C266_16030
symbol: C266_16030
gene_biotype: protein_coding
description:
  Nitrate ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_16035
symbol: C266_16035
gene_biotype: protein_coding
description:
  Response regulator receiver/ANTAR domain-containing protein; COG3707 Response regulator with putative antiterminator output domain.


ensembl_gene_id: C266_16045
symbol: C266_16045
gene_biotype: protein_coding
description:
  Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: C266_16055
symbol: C266_16055
gene_biotype: protein_coding
description:
  Nitrite reductase (NAD(P)H), large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: C266_16075
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.


ensembl_gene_id: C266_16080
symbol: C266_16080
gene_biotype: protein_coding
description:
  NAD-dependent epimerase/dehydratase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: C266_16105
symbol: C266_16105
gene_biotype: protein_coding
description:
  Secretion protein HlyD family; COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_16145
symbol: C266_16145
gene_biotype: protein_coding
description:
  Periplasmic multidrug efflux lipoprotein precursor; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_16160
symbol: C266_16160
gene_biotype: protein_coding
description:
  HAF family extracellular repeat-containing protein; COG5563 Predicted integral membrane proteins containing uncharacterized repeats.


ensembl_gene_id: C266_16190
symbol: C266_16190
gene_biotype: protein_coding
description:
  Glutamine ABC transporter substrate binding protein GlnH; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: C266_16195
symbol: C266_16195
gene_biotype: protein_coding
description:
  Glutamate/aspartate ABC transporter permease GltJ; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: C266_16215
symbol: C266_16215
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing enzyme family protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: C266_16225
symbol: C266_16225
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: C266_16285
symbol: C266_16285
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_16320
symbol: C266_16320
gene_biotype: protein_coding
description:
  Sigma54-dependent transcription regulator protein; COG3284 Transcriptional activator of acetoin/glycerol metabolism.


ensembl_gene_id: C266_16340
symbol: C266_16340
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: C266_16350
symbol: C266_16350
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_16355
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: C266_16385
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: C266_16390
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: C266_16395
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: C266_16400
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: C266_16405
symbol: C266_16405
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate transporter periplasmic binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: C266_16410
symbol: C266_16410
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: C266_16415
symbol: ugpE
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate transporter membrane protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: C266_16420
symbol: ugpC
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate transporter ATP-binding subunit; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: C266_16425
symbol: ugpQ
gene_biotype: protein_coding
description:
  Cytoplasmic glycerophosphodiester phosphodiesterase; COG0584 Glycerophosphoryl diester phosphodiesterase.


ensembl_gene_id: C266_16430
symbol: C266_16430
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: C266_16445
symbol: C266_16445
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: C266_16450
symbol: C266_16450
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: C266_16455
symbol: C266_16455
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: C266_16460
symbol: C266_16460
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: C266_16465
symbol: msbA
gene_biotype: protein_coding
description:
  Phospholipid-lipopolysaccharide ABC transporter; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: C266_16495
symbol: gluQ
gene_biotype: protein_coding
description:
  glutamyl-Q tRNA(Asp) ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: C266_16575
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: C266_16590
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: C266_16595
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...]


ensembl_gene_id: C266_16600
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: C266_16610
symbol: C266_16610
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: C266_16625
symbol: C266_16625
gene_biotype: protein_coding
description:
  Membrane bound O-acyl transferase; COG1696 Predicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: C266_16640
symbol: C266_16640
gene_biotype: protein_coding
description:
  Multidrug efflux system, subunit B; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: C266_16645
symbol: C266_16645
gene_biotype: protein_coding
description:
  Putative resistance transmembrane protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_16650
symbol: C266_16650
gene_biotype: protein_coding
description:
  Two component response regulator transcription regulator protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_16655
symbol: C266_16655
gene_biotype: protein_coding
description:
  Sensor histidine kinase in two-component regulatory system up with Au; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: C266_16665
symbol: C266_16665
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: C266_16670
symbol: C266_16670
gene_biotype: protein_coding
description:
  Major facilitator superfamily (MFS) multidrug efflux pump; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_16710
symbol: C266_16710
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: C266_16720
symbol: C266_16720
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter, inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: C266_16770
symbol: C266_16770
gene_biotype: protein_coding
description:
  RND family efflux transporter mfp subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_16775
symbol: macB-2
gene_biotype: protein_coding
description:
  ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: C266_16795
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: C266_16870
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: C266_16885
symbol: C266_16885
gene_biotype: protein_coding
description:
  Fmu (Sun) /eukaryotic nucleolar NOL1/Nop2p, tRNA and rRNA cytosine-C5-methylase; COG0144 tRNA and rRNA cytosine-C5-methylases.


ensembl_gene_id: C266_16890
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: C266_16895
symbol: C266_16895
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.


ensembl_gene_id: C266_16900
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: C266_16905
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: C266_16910
symbol: C266_16910
gene_biotype: protein_coding
description:
  Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: C266_16920
symbol: C266_16920
gene_biotype: protein_coding
description:
  Luciferase family oxidoreductase, group 1; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: C266_16925
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: C266_16930
symbol: C266_16930
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding protein ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: C266_16935
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: C266_16945
symbol: C266_16945
gene_biotype: protein_coding
description:
  Naphthalene 1,2-dioxygenase system ferredoxin subunit; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: C266_16955
symbol: C266_16955
gene_biotype: protein_coding
description:
  Salicylate 5-hydroxylase large oxygenase component NagG; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: C266_16960
symbol: C266_16960
gene_biotype: protein_coding
description:
  Oxidoreductase faD-binding domain-containing protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: C266_17010
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: C266_17025
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: C266_17035
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: C266_17040
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: C266_17060
symbol: murJ
gene_biotype: protein_coding
description:
  Virulence factor mviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: C266_17075
symbol: C266_17075
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: C266_17080
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: C266_17100
symbol: plsY
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: C266_17115
symbol: xerD
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: C266_17120
symbol: queG
gene_biotype: protein_coding
description:
  Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: C266_17140
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: C266_17145
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: C266_17150
symbol: C266_17150
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter system inner membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: C266_17165
symbol: C266_17165
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter system inner membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: C266_17200
symbol: C266_17200
gene_biotype: protein_coding
description:
  DnaA regulatory inactivator Hda; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family.


ensembl_gene_id: C266_17210
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: C266_17215
symbol: C266_17215
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: C266_17225
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: C266_17230
symbol: C266_17230
gene_biotype: protein_coding
description:
  Sensor histidine kinase transcription regulator protein; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: C266_17270
symbol: C266_17270
gene_biotype: protein_coding
description:
  Adenine nucleotide alpha hydrolases-like protein; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control.


ensembl_gene_id: C266_17341
symbol: fusA-2
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: C266_17346
symbol: pdxY
gene_biotype: protein_coding
description:
  Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: C266_17396
symbol: C266_17396
gene_biotype: protein_coding
description:
  N-acetyltransferase, (GNAT) family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: C266_17406
symbol: C266_17406
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_17411
symbol: C266_17411
gene_biotype: protein_coding
description:
  MarR family transcriptional regulator with acetyltransferase activity; COG1846 Transcriptional regulators.


ensembl_gene_id: C266_17416
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: C266_17426
symbol: C266_17426
gene_biotype: protein_coding
description:
  Short chain dehydrogenase/reductase family oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: C266_17431
symbol: C266_17431
gene_biotype: protein_coding
description:
  Monooxygenase flavin-binding family protein; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: C266_17436
symbol: C266_17436
gene_biotype: protein_coding
description:
  Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: C266_17466
symbol: C266_17466
gene_biotype: protein_coding
description:
  Putative addiction module antidote protein, CopG/Arc/MetJ family; COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain.


ensembl_gene_id: C266_17541
symbol: dusA
gene_biotype: protein_coding
description:
  YjbN family TIM-barrel protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: C266_17591
symbol: C266_17591
gene_biotype: protein_coding
description:
  Arsenite-activated ATPase subunit ArsA; Anion-transporting ATPase; Belongs to the arsA ATPase family.


ensembl_gene_id: C266_17616
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: C266_17621
symbol: bpt
gene_biotype: protein_coding
description:
  arginyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: C266_17626
symbol: pyrD-2
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: C266_17631
symbol: C266_17631
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: C266_17641
symbol: C266_17641
gene_biotype: protein_coding
description:
  Iron-sulfur cluster binding protein; COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain.


ensembl_gene_id: C266_17686
symbol: C266_17686
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: C266_17696
symbol: C266_17696
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: C266_17701
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: C266_17716
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: C266_17741
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: C266_17756
symbol: C266_17756
gene_biotype: protein_coding
description:
  Protein hflK, cofactor of ATP-dependent protease FtsH; HflC and HflK could encode or regulate a protease.


ensembl_gene_id: C266_17761
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: C266_17766
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: C266_17771
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: C266_17776
symbol: bamB
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: C266_17791
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: C266_17801
symbol: rlmN
gene_biotype: protein_coding
description:
  Radical SAM enzyme, Cfr family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: C266_17806
symbol: ndk
gene_biotype: protein_coding
description:
  Multifunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: C266_17816
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA m(5)U1939 methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: C266_17821
symbol: C266_17821
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.


ensembl_gene_id: C266_17826
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: C266_17836
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: C266_17841
symbol: surE
gene_biotype: protein_coding
description:
  5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: C266_17856
symbol: C266_17856
gene_biotype: protein_coding
description:
  NMT1/THI5 like domain-containing protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_17861
symbol: C266_17861
gene_biotype: protein_coding
description:
  CAIB/BAIF family protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: C266_17866
symbol: C266_17866
gene_biotype: protein_coding
description:
  Transcriptional regulator protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: C266_17911
symbol: C266_17911
gene_biotype: protein_coding
description:
  Sigma-54 dependent transcription regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: C266_17916
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: C266_17921
symbol: C266_17921
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: C266_17926
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: C266_17936
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: C266_17946
symbol: C266_17946
gene_biotype: protein_coding
description:
  Iron binding protein component of ABC iron transporter; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: C266_17961
symbol: C266_17961
gene_biotype: protein_coding
description:
  COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_17966
symbol: C266_17966
gene_biotype: protein_coding
description:
  ABC peptide transporter, inner membrane subunit; COG4239 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: C266_17971
symbol: C266_17971
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG4174 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: C266_17976
symbol: C266_17976
gene_biotype: protein_coding
description:
  Family 5 extracellular solute-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: C266_18001
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: C266_18006
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: C266_18026
symbol: C266_18026
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase a (rotamase a); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: C266_18031
symbol: C266_18031
gene_biotype: protein_coding
description:
  Cyclophilin type peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: C266_18036
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: C266_18046
symbol: trmJ
gene_biotype: protein_coding
description:
  tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: C266_18051
symbol: C266_18051
gene_biotype: protein_coding
description:
  Inositol-1(or 4)-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: C266_18056
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: C266_18066
symbol: ssuB
gene_biotype: protein_coding
description:
  ABC transporter-like protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: C266_18076
symbol: ssuD
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: C266_18111
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: C266_18116
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: C266_18121
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: C266_18141
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: C266_18146
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: C266_18151
symbol: C266_18151
gene_biotype: protein_coding
description:
  DNA methylase N-4/N-6 domain-containing protein; COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: C266_18156
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: C266_18166
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: C266_18176
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: C266_18181
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: C266_18186
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: C266_18196
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: C266_18211
symbol: sdhB
gene_biotype: protein_coding
description:
  COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: C266_18216
symbol: sdhA
gene_biotype: protein_coding
description:
  COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: C266_18236
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: C266_18251
symbol: C266_18251
gene_biotype: protein_coding
description:
  Transcriptional regulator Ada; COG2169 Adenosine deaminase; DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine--protein-cysteine S-methyltransferase.


ensembl_gene_id: C266_18256
symbol: C266_18256
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: C266_18356
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: C266_18366
symbol: C266_18366
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: C266_18371
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: C266_18376
symbol: C266_18376
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: C266_18381
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: C266_18386
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: C266_18391
symbol: C266_18391
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: C266_18396
symbol: C266_18396
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: C266_18406
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: C266_18411
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: C266_18416
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: C266_18426
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: C266_18431
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: C266_18436
symbol: C266_18436
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: C266_18451
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: C266_18471
symbol: C266_18471
gene_biotype: protein_coding
description:
  Beta-lactamase domain-containing protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.


ensembl_gene_id: C266_18491
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: C266_18501
symbol: C266_18501
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.


ensembl_gene_id: C266_18521
symbol: C266_18521
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase/acetyltransferase; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.


ensembl_gene_id: C266_18526
symbol: C266_18526
gene_biotype: protein_coding
description:
  Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: C266_18536
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: C266_18541
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: C266_18546
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.


ensembl_gene_id: C266_18551
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: C266_18571
symbol: lolD
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: C266_18576
symbol: C266_18576
gene_biotype: protein_coding
description:
  LPT family ABC transporter permease; COG4591 ABC-type transport system, involved in lipoprotein release, permease component.


ensembl_gene_id: C266_18601
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: C266_18641
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: C266_18646
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: C266_18661
symbol: C266_18661
gene_biotype: protein_coding
description:
  Scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: C266_18666
symbol: iscS-2
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: C266_18681
symbol: C266_18681
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: C266_18686
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: C266_18706
symbol: C266_18706
gene_biotype: protein_coding
description:
  Ferredoxin; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: C266_18711
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: C266_18731
symbol: C266_18731
gene_biotype: protein_coding
description:
  Putative periplasmic cytochrome type-C oxidoreductase signal peptide protein; COG2863 Cytochrome c553.


ensembl_gene_id: C266_18771
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: C266_18811
symbol: C266_18811
gene_biotype: protein_coding
description:
  Putative transporter (MFS superfamily) protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_18816
symbol: C266_18816
gene_biotype: protein_coding
description:
  Putative transcriptional regulatory protein,LysR family; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: C266_18826
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: C266_18841
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: C266_18846
symbol: C266_18846
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: C266_18896
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: C266_18941
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: C266_18946
symbol: C266_18946
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: C266_18971
symbol: C266_18971
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_18976
symbol: C266_18976
gene_biotype: protein_coding
description:
  Receptor family ligand binding region family protein 7; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: C266_18981
symbol: C266_18981
gene_biotype: protein_coding
description:
  Peptidase U62 modulator of DNA gyrase; COG0312 Predicted Zn-dependent proteases and their inactivated homologs.


ensembl_gene_id: C266_18996
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: C266_19006
symbol: rsgA
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: C266_19011
symbol: cobD-2
gene_biotype: protein_coding
description:
  CobD/CbiB family protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: C266_19016
symbol: C266_19016
gene_biotype: protein_coding
description:
  MutT/NUDIX NTP pyrophosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: C266_19021
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: C266_19026
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: C266_19031
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: C266_19041
symbol: C266_19041
gene_biotype: protein_coding
description:
  Putative soluble quinoprotein glucose/sorbosone dehydrogenase; COG2133 Glucose/sorbosone dehydrogenases.


ensembl_gene_id: C266_19086
symbol: C266_19086
gene_biotype: protein_coding
description:
  Non-heme haloperoxidase ThcF; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: C266_19168
symbol: C266_19168
gene_biotype: protein_coding
description:
  Utative DNA-binding transcriptional regulator; COG4197 Uncharacterized protein conserved in bacteria, prophage-related.


ensembl_gene_id: C266_19300
symbol: rhlE
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: C266_19425
symbol: C266_19425
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein CapD; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: C266_19430
symbol: C266_19430
gene_biotype: protein_coding
description:
  Glycosyl transferase, family 4; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: C266_19435
symbol: C266_19435
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: C266_19465
symbol: C266_19465
gene_biotype: protein_coding
description:
  COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: C266_19470
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: C266_19475
symbol: fcl
gene_biotype: protein_coding
description:
  NAD-dependent epimerase/dehydratase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: C266_19485
symbol: C266_19485
gene_biotype: protein_coding
description:
  Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: C266_19495
symbol: C266_19495
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein RfbH; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: C266_19515
symbol: C266_19515
gene_biotype: protein_coding
description:
  Putative glycosyltransferase O-antigen related protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: C266_19520
symbol: C266_19520
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: C266_19540
symbol: C266_19540
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: C266_19615
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: C266_19620
symbol: C266_19620
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: C266_19625
symbol: rsmI
gene_biotype: protein_coding
description:
  uroporphyrin-III C/tetrapyrrole methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: C266_19630
symbol: C266_19630
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1101 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: C266_19635
symbol: C266_19635
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4120 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_19640
symbol: C266_19640
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG2984 ABC-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: C266_19645
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: C266_19690
symbol: C266_19690
gene_biotype: protein_coding
description:
  Cyclohexadienyl dehydratase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: C266_19695
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: C266_19700
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: C266_19715
symbol: putA
gene_biotype: protein_coding
description:
  Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: C266_19720
symbol: C266_19720
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: C266_19760
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: C266_19765
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: C266_19770
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: C266_19780
symbol: rep
gene_biotype: protein_coding
description:
  UvrD/REP helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: C266_19795
symbol: C266_19795
gene_biotype: protein_coding
description:
  Outer membrane autotransporter; COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain.


ensembl_gene_id: C266_19805
symbol: C266_19805
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: C266_19860
symbol: C266_19860
gene_biotype: protein_coding
description:
  LuxR family DNA-binding response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: C266_19865
symbol: C266_19865
gene_biotype: protein_coding
description:
  Flagellin/flagellar hook associated protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: C266_19870
symbol: C266_19870
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: C266_19890
symbol: C266_19890
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.


ensembl_gene_id: C266_19915
symbol: C266_19915
gene_biotype: protein_coding
description:
  Flagellum-specific ATP synthase FliI; COG1157 Flagellar biosynthesis/type III secretory pathway ATPase.


ensembl_gene_id: C266_19930
symbol: C266_19930
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: C266_19950
symbol: fliP-2
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: C266_19955
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: C266_19960
symbol: C266_19960
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: C266_19980
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: C266_20005
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: C266_20015
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: C266_20035
symbol: fliA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: C266_20050
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: C266_20055
symbol: flhB-2
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: C266_20060
symbol: C266_20060
gene_biotype: protein_coding
description:
  Chemotaxis regulator CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: C266_20070
symbol: cheB-2
gene_biotype: protein_coding
description:
  Chemotaxis-specific protein-glutamate methyltransferase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: C266_20075
symbol: cheD
gene_biotype: protein_coding
description:
  Chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: C266_20080
symbol: C266_20080
gene_biotype: protein_coding
description:
  Methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: C266_20105
symbol: C266_20105
gene_biotype: protein_coding
description:
  CheA Signal transduction histidine Kinases(STHK); COG0643 Chemotaxis protein histidine kinase and related kinases.


ensembl_gene_id: C266_20125
symbol: flhC
gene_biotype: protein_coding
description:
  Transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: C266_20130
symbol: flhD
gene_biotype: protein_coding
description:
  Transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: C266_20135
symbol: C266_20135
gene_biotype: protein_coding
description:
  Bcr/CflA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_20145
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: C266_20150
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: C266_20155
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: C266_20160
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: C266_20165
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: C266_20170
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: C266_20175
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: C266_20180
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: C266_20205
symbol: C266_20205
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: C266_20210
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: C266_20215
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: C266_20239
symbol: C266_20239
gene_biotype: protein_coding
description:
  Transglutaminase family protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: C266_20289
symbol: C266_20289
gene_biotype: protein_coding
description:
  Hydroxyisourate hydrolase; COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: C266_20299
symbol: C266_20299
gene_biotype: protein_coding
description:
  Hydroxydechloroatrazine ethylaminohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: C266_20314
symbol: C266_20314
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_20319
symbol: C266_20319
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_20324
symbol: C266_20324
gene_biotype: protein_coding
description:
  Basic membrane lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: C266_20349
symbol: C266_20349
gene_biotype: protein_coding
description:
  Outer membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: C266_20354
symbol: C266_20354
gene_biotype: protein_coding
description:
  Diguanylate cyclase; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.


ensembl_gene_id: C266_20359
symbol: C266_20359
gene_biotype: protein_coding
description:
  Diguanylate cyclase domain protein / diguanylate phosphodiesterase domain protein; COG2199 FOG: GGDEF domain.


ensembl_gene_id: C266_20384
symbol: C266_20384
gene_biotype: protein_coding
description:
  Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: C266_20389
symbol: cpdA-3
gene_biotype: protein_coding
description:
  3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: C266_20439
symbol: C266_20439
gene_biotype: protein_coding
description:
  Putative ferric siderophore receptor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: C266_20444
symbol: C266_20444
gene_biotype: protein_coding
description:
  PepSY-associated TM helix domain-containing protein; COG3182 Uncharacterized iron-regulated membrane protein.


ensembl_gene_id: C266_20469
symbol: C266_20469
gene_biotype: protein_coding
description:
  Oxidoreductase alpha (molybdopterin) subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: C266_20474
symbol: C266_20474
gene_biotype: protein_coding
description:
  Molybdate metabolism transcriptional regulator; COG2005 N-terminal domain of molybdenum-binding protein.


ensembl_gene_id: C266_20479
symbol: C266_20479
gene_biotype: protein_coding
description:
  NAD-dependent formate dehydrogenase subunit gamma; COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.


ensembl_gene_id: C266_20484
symbol: C266_20484
gene_biotype: protein_coding
description:
  NAD-dependent formate dehydrogenase subunit beta; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.


ensembl_gene_id: C266_20494
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: C266_20514
symbol: C266_20514
gene_biotype: protein_coding
description:
  Putative deoxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: C266_20519
symbol: C266_20519
gene_biotype: protein_coding
description:
  Sodium/chloride ion channel; COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: C266_20534
symbol: C266_20534
gene_biotype: protein_coding
description:
  Transporter divalent anion:Na+ symporter, DASS family protein; COG0471 Di- and tricarboxylate transporters.


ensembl_gene_id: C266_20554
symbol: C266_20554
gene_biotype: protein_coding
description:
  Spermidine/putrescine transport system substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: C266_20599
symbol: C266_20599
gene_biotype: protein_coding
description:
  Drug resistance transporter EmrB/QacA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: C266_20624
symbol: C266_20624
gene_biotype: protein_coding
description:
  COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: C266_20639
symbol: C266_20639
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_20674
symbol: C266_20674
gene_biotype: protein_coding
description:
  Multidrug resistance protein (HlyD family), EmrA-like secretion; COG1566 Multidrug resistance efflux pump.


ensembl_gene_id: C266_20689
symbol: C266_20689
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG3300 MHYT domain (predicted integral membrane sensor domain).


ensembl_gene_id: C266_20744
symbol: C266_20744
gene_biotype: protein_coding
description:
  Hipa n-terminal domain-containing protein; COG3550 Uncharacterized protein related to capsule biosynthesis enzymes.


ensembl_gene_id: C266_20789
symbol: C266_20789
gene_biotype: protein_coding
description:
  AcrB/AcrD/AcrF family cation efflux protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: C266_20854
symbol: C266_20854
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: C266_20864
symbol: C266_20864
gene_biotype: protein_coding
description:
  COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: C266_20904
symbol: C266_20904
gene_biotype: protein_coding
description:
  Transcription regulator protein, arsenical resistance operon repressor; COG0640 Predicted transcriptional regulators.


ensembl_gene_id: C266_20929
symbol: C266_20929
gene_biotype: protein_coding
description:
  Nmt1/thi5 like domain-containing protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_20999
symbol: C266_20999
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: C266_21119
symbol: C266_21119
gene_biotype: protein_coding
description:
  Putative enoyl-CoA hydratase/isomerase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: C266_21124
symbol: aroK-2
gene_biotype: protein_coding
description:
  Anaerobic benzoate catabolism transcriptional regulator; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: C266_21139
symbol: dapA-3
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: C266_21149
symbol: C266_21149
gene_biotype: protein_coding
description:
  snoaL-like polyketide cyclase family protein 2; COG4922 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: C266_21219
symbol: C266_21219
gene_biotype: protein_coding
description:
  Poly-beta-hydroxybutyrate polymerase domain-containing protein; COG3243 Poly(3-hydroxyalkanoate) synthetase.


ensembl_gene_id: C266_21229
symbol: C266_21229
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: C266_21239
symbol: C266_21239
gene_biotype: protein_coding
description:
  RND family multidrug efflux protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: C266_21279
symbol: C266_21279
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) iron-sulfur domain-containing protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: C266_21284
symbol: potA-2
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: C266_21294
symbol: C266_21294
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: C266_21304
symbol: C266_21304
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: C266_21324
symbol: C266_21324
gene_biotype: protein_coding
description:
  Cellulose synthase catalytic subunit; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.


ensembl_gene_id: C266_21339
symbol: C266_21339
gene_biotype: protein_coding
description:
  endo-1,4-D-glucanase; COG3405 Endoglucanase Y; Belongs to the glycosyl hydrolase 8 (cellulase D) family.


ensembl_gene_id: C266_21344
symbol: C266_21344
gene_biotype: protein_coding
description:
  Cellulose synthase regulator protein; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: C266_21364
symbol: C266_21364
gene_biotype: protein_coding
description:
  COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily.


ensembl_gene_id: C266_21399
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: C266_21404
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: C266_21409
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: C266_21424
symbol: C266_21424
gene_biotype: protein_coding
description:
  Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_21429
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: C266_21459
symbol: C266_21459
gene_biotype: protein_coding
description:
  CoA-transferase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: C266_21499
symbol: C266_21499
gene_biotype: protein_coding
description:
  Secreted pili protein involved in motility and biofilm formation; COG5430 Uncharacterized secreted protein.


ensembl_gene_id: C266_21509
symbol: argD-2
gene_biotype: protein_coding
description:
  Bifunctional succinylornithine transaminase/acetylornithine transaminase; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: C266_21524
symbol: C266_21524
gene_biotype: protein_coding
description:
  Glutamine ABC transporter periplasmic protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: C266_21529
symbol: C266_21529
gene_biotype: protein_coding
description:
  Acetolactate synthase large subunit biosynthetic type; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: C266_21564
symbol: C266_21564
gene_biotype: protein_coding
description:
  Flavodoxin/oxidoreductase NAD binding domain protein; COG3182 Uncharacterized iron-regulated membrane protein.


ensembl_gene_id: C266_21574
symbol: C266_21574
gene_biotype: protein_coding
description:
  Alpha, alpha-trehalose-phosphate synthase(UDP- forming); Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.


ensembl_gene_id: C266_21599
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: C266_21604
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: C266_21639
symbol: acpP-2
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: C266_21669
symbol: C266_21669
gene_biotype: protein_coding
description:
  Signal peptide protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: C266_21679
symbol: C266_21679
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: C266_21699
symbol: C266_21699
gene_biotype: protein_coding
description:
  Putative lipoprotein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_21704
symbol: C266_21704
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: C266_21759
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: C266_21764
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: C266_21774
symbol: C266_21774
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: C266_21789
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: C266_21799
symbol: nnrE
gene_biotype: protein_coding
description:
  Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]


ensembl_gene_id: C266_21809
symbol: C266_21809
gene_biotype: protein_coding
description:
  ABC transporter ATPase; COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: C266_21829
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: C266_21834
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: C266_21839
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: C266_21844
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: C266_21884
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: C266_21894
symbol: minC
gene_biotype: protein_coding
description:
  Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: C266_21924
symbol: C266_21924
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: C266_21939
symbol: C266_21939
gene_biotype: protein_coding
description:
  ABC transporter transmembrane region:ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: C266_21949
symbol: C266_21949
gene_biotype: protein_coding
description:
  Cyanophycin synthetase; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; Belongs to the MurCDEF family.


ensembl_gene_id: C266_21979
symbol: C266_21979
gene_biotype: protein_coding
description:
  Enzyme-regulator fusion protein; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: C266_22019
symbol: C266_22019
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: C266_22024
symbol: map-2
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: C266_22108
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: C266_22113
symbol: C266_22113
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: C266_22173
symbol: C266_22173
gene_biotype: protein_coding
description:
  ABC transporter, fused ATPase/inner membrane protein; COG4178 ABC-type uncharacterized transport system, permease and ATPase components.


ensembl_gene_id: C266_22188
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: C266_22203
symbol: C266_22203
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.


ensembl_gene_id: C266_22213
symbol: C266_22213
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: C266_22223
symbol: C266_22223
gene_biotype: protein_coding
description:
  Toluene tolerance family protein; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.


ensembl_gene_id: C266_22248
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: C266_22253
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: C266_22258
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: C266_22283
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: C266_22288
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.


ensembl_gene_id: C266_22293
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: C266_22298
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: C266_22313
symbol: C266_22313
gene_biotype: protein_coding
description:
  HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: C266_22318
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: C266_22323
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: C266_22328
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: C266_22333
symbol: C266_22333
gene_biotype: protein_coding
description:
  2-alkenal reductase; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: C266_22343
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: C266_22348
symbol: C266_22348
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit (Rieske Fe-S protein); Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: C266_22353
symbol: C266_22353
gene_biotype: protein_coding
description:
  Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: C266_22400
symbol: argC-2
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: C266_22415
symbol: C266_22415
gene_biotype: protein_coding
description:
  MerR family transcriptional regulator; COG3315 O-Methyltransferase involved in polyketide biosynthesis; Belongs to the UPF0677 family.


ensembl_gene_id: C266_22420
symbol: C266_22420
gene_biotype: protein_coding
description:
  Putative Dipeptidyl aminopeptidase/acylaminoacyl-peptidase; COG0412 Dienelactone hydrolase and related enzymes.


ensembl_gene_id: C266_22435
symbol: C266_22435
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: C266_22440
symbol: C266_22440
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG4134 ABC-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: C266_22445
symbol: C266_22445
gene_biotype: protein_coding
description:
  COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_22480
symbol: C266_22480
gene_biotype: protein_coding
description:
  5-dehydro-4-deoxyglucarate dehydratase; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: C266_22560
symbol: C266_22560
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein.


ensembl_gene_id: C266_22635
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: C266_22640
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: C266_22645
symbol: C266_22645
gene_biotype: protein_coding
description:
  Alanine racemase; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: C266_22660
symbol: C266_22660
gene_biotype: protein_coding
description:
  Regulatory protein GntR, HTH:Aminotransferase, class I and II; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: C266_22685
symbol: C266_22685
gene_biotype: protein_coding
description:
  Cob(i)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: C266_22690
symbol: C266_22690
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: C266_22695
symbol: C266_22695
gene_biotype: protein_coding
description:
  Microcin-processing peptidase 2; COG0312 Predicted Zn-dependent proteases and their inactivated homologs.


ensembl_gene_id: C266_22710
symbol: glnE
gene_biotype: protein_coding
description:
  Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]


ensembl_gene_id: C266_22720
symbol: ppnK
gene_biotype: protein_coding
description:
  NAD(+)/NADH kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: C266_22725
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: C266_22735
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: C266_22740
symbol: C266_22740
gene_biotype: protein_coding
description:
  COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).


ensembl_gene_id: C266_22750
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: C266_22770
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: C266_22801
symbol: C266_22801
gene_biotype: protein_coding
description:
  Capsular synthesis two-component sensor kinase and response regulator transcription protein; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: C266_22861
symbol: C266_22861
gene_biotype: protein_coding
description:
  Polysaccharide deacetylase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: C266_23021
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.


ensembl_gene_id: C266_23036
symbol: C266_23036
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase-like FMN-binding protein; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: C266_23071
symbol: C266_23071
gene_biotype: protein_coding
description:
  Pentachlorophenol monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_23116
symbol: C266_23116
gene_biotype: protein_coding
description:
  DNA-O6-methylguanine--protein-cysteine S-methyltransferase/transcriptional regulator Ada; COG2169 Adenosine deaminase.


ensembl_gene_id: C266_23281
symbol: C266_23281
gene_biotype: protein_coding
description:
  Helix-hairpin-helix DNA-binding motif-containing protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: C266_23331
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: C266_23336
symbol: bioD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: C266_23341
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: C266_23351
symbol: C266_23351
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: C266_23386
symbol: C266_23386
gene_biotype: protein_coding
description:
  Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: C266_23391
symbol: aceK
gene_biotype: protein_coding
description:
  Bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: C266_23461
symbol: C266_23461
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: C266_23466
symbol: C266_23466
gene_biotype: protein_coding
description:
  Homocysteine S-methyltransferase; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.


ensembl_gene_id: C266_23496
symbol: C266_23496
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_23503
symbol: C266_23503
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: C266_23523
symbol: C266_23523
gene_biotype: protein_coding
description:
  Dipeptide ABC transport ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_23528
symbol: C266_23528
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: C266_23608
symbol: C266_23608
gene_biotype: protein_coding
description:
  Phosphinothricin acetyltransferase (antibiotic resistance) protein; COG1247 Sortase and related acyltransferases.


ensembl_gene_id: C266_23613
symbol: C266_23613
gene_biotype: protein_coding
description:
  Acylaldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: C266_23618
symbol: C266_23618
gene_biotype: protein_coding
description:
  (2Fe-2S)-binding domain-containing protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: C266_23638
symbol: msrA
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: C266_23648
symbol: C266_23648
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.


ensembl_gene_id: C266_23668
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: C266_23673
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: C266_23698
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: C266_23763
symbol: C266_23763
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: C266_23778
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: C266_23783
symbol: purE
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: C266_23788
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: C266_23793
symbol: C266_23793
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: C266_23808
symbol: C266_23808
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein qseB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: C266_23843
symbol: C266_23843
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, ModE family protein; COG2005 N-terminal domain of molybdenum-binding protein.


ensembl_gene_id: C266_23863
symbol: modC
gene_biotype: protein_coding
description:
  Molybdate ABC transporter ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: C266_23868
symbol: C266_23868
gene_biotype: protein_coding
description:
  Molybdate ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: C266_23873
symbol: C266_23873
gene_biotype: protein_coding
description:
  Putative molybdate-binding periplasmic ABC transporter; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: C266_23883
symbol: C266_23883
gene_biotype: protein_coding
description:
  Acriflavin resistance periplasmic protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: C266_23948
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: C266_23953
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: C266_23958
symbol: kynB
gene_biotype: protein_coding
description:
  N-formyl-L-kynurenine/ N-Formylanthranilate amidohydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation.


ensembl_gene_id: C266_23973
symbol: C266_23973
gene_biotype: protein_coding
description:
  Flavin reductase domain-containing protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: C266_23993
symbol: C266_23993
gene_biotype: protein_coding
description:
  long-chain-fatty-acid--CoA ligase LcfB; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: C266_24003
symbol: C266_24003
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: C266_24018
symbol: hutG
gene_biotype: protein_coding
description:
  Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: C266_24043
symbol: fabV
gene_biotype: protein_coding
description:
  trans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: C266_24058
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: C266_24068
symbol: C266_24068
gene_biotype: protein_coding
description:
  UBA/ThiF-type NAD/FAD-binding protein; COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1.


ensembl_gene_id: C266_24088
symbol: C266_24088
gene_biotype: protein_coding
description:
  Multidrug resistance protein (hlyD family), emrA-like secretion; COG1566 Multidrug resistance efflux pump.


ensembl_gene_id: C266_24128
symbol: C266_24128
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: C266_24148
symbol: C266_24148
gene_biotype: protein_coding
description:
  Putative alanyl-tRNA synthetase; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.


ensembl_gene_id: C266_24153
symbol: C266_24153
gene_biotype: protein_coding
description:
  Aliphatic sulfonates ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: C266_24158
symbol: C266_24158
gene_biotype: protein_coding
description:
  Sulfonate ABC transporter ATP-binding protein SsuB; COG2010 Cytochrome c, mono- and diheme variants.


ensembl_gene_id: C266_24168
symbol: C266_24168
gene_biotype: protein_coding
description:
  Nitrate/sulfonate/bicarbonate family ABC transporter inner membrane subunit; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: C266_24193
symbol: C266_24193
gene_biotype: protein_coding
description:
  Cysteine dioxygenase type I; COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily.


ensembl_gene_id: C266_24218
symbol: C266_24218
gene_biotype: protein_coding
description:
  ATP-binding ABC transporter; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: C266_24223
symbol: C266_24223
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: C266_24233
symbol: C266_24233
gene_biotype: protein_coding
description:
  Putative ABC transporter, periplasmic protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: C266_24428
symbol: C266_24428
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: C266_24498
symbol: ftsI-2
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: C266_24538
symbol: C266_24538
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain-containing protein 1; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: C266_24548
symbol: C266_24548
gene_biotype: protein_coding
description:
  Lactonase (box pathway); COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: C266_24583
symbol: C266_24583
gene_biotype: protein_coding
description:
  benzoyl-CoA oxygenase, component A; COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit.


ensembl_gene_id: C266_24603
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: C266_24608
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: C266_24630
symbol: C266_24630
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: C266_24640
symbol: C266_24640
gene_biotype: protein_coding
description:
  Putative phenylacetic acid degradation oxidoreductase; COG1012 NAD-dependent aldehyde dehydrogenases.


ensembl_gene_id: C266_24655
symbol: C266_24655
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation- related thioesterase (PaaI); COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: C266_24660
symbol: C266_24660
gene_biotype: protein_coding
description:
  phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: C266_24685
symbol: C266_24685
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: C266_24690
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: C266_24705
symbol: C266_24705
gene_biotype: protein_coding
description:
  Multifunctional ribosome-associated ATPase/membrane protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: C266_24710
symbol: C266_24710
gene_biotype: protein_coding
description:
  Putative ABC transporter membrane protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: C266_24730
symbol: dsbD-2
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: C266_24740
symbol: dsbG
gene_biotype: protein_coding
description:
  Disulfide isomerase/thiol-disulfide oxidase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: C266_24750
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: C266_24765
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: C266_24790
symbol: azoR
gene_biotype: protein_coding
description:
  (Acyl-carrier-protein) phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: C266_24805
symbol: C266_24805
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: C266_24810
symbol: C266_24810
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis hydroxylase family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_24820
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: C266_24835
symbol: C266_24835
gene_biotype: protein_coding
description:
  MlrC domain-containing protein; Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC); Belongs to the peptidase M81 family.


ensembl_gene_id: C266_24885
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: C266_24890
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: C266_24895
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: C266_24905
symbol: ubiX-2
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: C266_24930
symbol: cheD-2
gene_biotype: protein_coding
description:
  Protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: C266_24940
symbol: C266_24940
gene_biotype: protein_coding
description:
  Transpatatin- like phospholipase domain-containing protein; COG1752 Predicted esterase of the alpha-beta hydrolase superfamily.


ensembl_gene_id: C266_24975
symbol: C266_24975
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: C266_25005
symbol: C266_25005
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthesis glucosyltransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.


ensembl_gene_id: C266_25010
symbol: C266_25010
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthesis glucosyltransferase; COG1922 Teichoic acid biosynthesis proteins; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: C266_25015
symbol: C266_25015
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthesis oxidoreductase; COG2303 Choline dehydrogenase and related flavoproteins.


ensembl_gene_id: C266_25075
symbol: C266_25075
gene_biotype: protein_coding
description:
  Membrane bound O-acyl transferase MBOAT family protein; COG1696 Predicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: C266_25110
symbol: C266_25110
gene_biotype: protein_coding
description:
  Bacteriophage N4 adsorption protein B; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.


ensembl_gene_id: C266_25225
symbol: C266_25225
gene_biotype: protein_coding
description:
  5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: C266_25235
symbol: C266_25235
gene_biotype: protein_coding
description:
  Monooxygenase FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: C266_25260
symbol: C266_25260
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin outer membrane protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: C266_25310
symbol: C266_25310
gene_biotype: protein_coding
description:
  Proline permease; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: C266_25315
symbol: C266_25315
gene_biotype: protein_coding
description:
  Extracellular serine protease; COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain.


ensembl_gene_id: C266_25330
symbol: C266_25330
gene_biotype: protein_coding
description:
  Integrase; COG2826 Transposase and inactivated derivatives, IS30 family; overlaps another CDS with the same product name.


ensembl_gene_id: C266_25435
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: C266_25475
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: C266_25480
symbol: C266_25480
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) flavoprotein subunit alpha; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: C266_25490
symbol: C266_25490
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: C266_25575
symbol: C266_25575
gene_biotype: protein_coding
description:
  Type II/IV secretion system secretin, associated with Flp pilus assembly; COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: C266_25615
symbol: C266_25615
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: C266_25625
symbol: kup
gene_biotype: protein_coding
description:
  Kup system potassium uptake protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


