# geneInfo

ensembl_gene_id: OI25_1006
symbol: OI25_1006
gene_biotype: protein_coding
description:
  THUMP domain protein; [L] COG0116 Predicted N6-adenine-specific DNA methylase; Belongs to the methyltransferase superfamily.


ensembl_gene_id: OI25_1009
symbol: OI25_1009
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: OI25_1011
symbol: OI25_1011
gene_biotype: protein_coding
description:
  Hypothetical protein; Alanine dehydrogenase/PNT, C-terminal domain protein; [C] COG3288 NAD/NADP transhydrogenase alpha subunit.


ensembl_gene_id: OI25_1012
symbol: nudJ
gene_biotype: protein_coding
description:
  NUDIX domain protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: OI25_1013
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: OI25_1014
symbol: OI25_1014
gene_biotype: protein_coding
description:
  Hypothetical protein; Conserved region in glutamate synthase family protein; [E] COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.


ensembl_gene_id: OI25_1015
symbol: OI25_1015
gene_biotype: protein_coding
description:
  fkbM_fam: methyltransferase, FkbM family domain protein; [QR] COG0500 SAM-dependent methyltransferases.


ensembl_gene_id: OI25_1018
symbol: OI25_1018
gene_biotype: protein_coding
description:
  HAD-SF-IIIA: HAD hydrolase, family IIIA domain protein; [E] COG0241 Histidinol phosphatase and related phosphatases.


ensembl_gene_id: OI25_102
symbol: sufS
gene_biotype: protein_coding
description:
  sufS: cysteine desulfurase, SufS family protein; [E] COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: OI25_1023
symbol: OI25_1023
gene_biotype: protein_coding
description:
  AMP-binding enzyme family protein; [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: OI25_1026
symbol: OI25_1026
gene_biotype: protein_coding
description:
  Bacterial regulatory helix-turn-helix, lysR family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: OI25_1029
symbol: OI25_1029
gene_biotype: protein_coding
description:
  eamA-like transporter family protein; [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: OI25_1030
symbol: rsmA
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: OI25_1031
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: OI25_1032
symbol: surA
gene_biotype: protein_coding
description:
  PPIC-type PPIASE domain protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: OI25_1033
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance family protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: OI25_1035
symbol: OI25_1035
gene_biotype: protein_coding
description:
  Nucleotidyl transferase family protein; [MJ] COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: OI25_1036
symbol: OI25_1036
gene_biotype: protein_coding
description:
  ABC transporter family protein; [O] COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components.


ensembl_gene_id: OI25_1042
symbol: OI25_1042
gene_biotype: protein_coding
description:
  Beta-lactamase family protein; [V] COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: OI25_1046
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: OI25_1048
symbol: OI25_1048
gene_biotype: protein_coding
description:
  acCoA-C-Actrans: acetyl-CoA C-acyltransferase family protein; [I] COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: OI25_1050
symbol: OI25_1050
gene_biotype: protein_coding
description:
  Hypothetical protein; acyl-CoA dehydrogenase, N-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases.


ensembl_gene_id: OI25_1053
symbol: clsB
gene_biotype: protein_coding
description:
  PLD-like domain protein; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: OI25_1054
symbol: OI25_1054
gene_biotype: protein_coding
description:
  NUDIX domain protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: OI25_1055
symbol: aspS
gene_biotype: protein_coding
description:
  aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: OI25_1057
symbol: OI25_1057
gene_biotype: protein_coding
description:
  cxxC_CxxC_SSSS: regulatory, FmdB family domain protein; [S] COG2331 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_1059
symbol: ubiB
gene_biotype: protein_coding
description:
  2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: OI25_1062
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase family protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: OI25_1064
symbol: OI25_1064
gene_biotype: protein_coding
description:
  Histidine triad (HIT) protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: OI25_1066
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: OI25_1068
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: OI25_1069
symbol: OI25_1069
gene_biotype: protein_coding
description:
  Endoribonuclease L-PSP family protein; [J] COG0251 Putative translation initiation inhibitor, yjgF family.


ensembl_gene_id: OI25_1070
symbol: OI25_1070
gene_biotype: protein_coding
description:
  Hypothetical protein; D-aminoacylase, C-terminal region family protein; [Q] COG3653 N-acyl-D-aspartate/D-glutamate deacylase.


ensembl_gene_id: OI25_1072
symbol: OI25_1072
gene_biotype: protein_coding
description:
  Putative D-serine deaminase (D-serine dehydratase) protein; [E] COG3616 Predicted amino acid aldolase or racemase.


ensembl_gene_id: OI25_1074
symbol: OI25_1074
gene_biotype: protein_coding
description:
  Sugar (and other) transporter family protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_108
symbol: OI25_108
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase fold family protein; [I] COG2272 Carboxylesterase type B; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: OI25_1081
symbol: aqpZ2
gene_biotype: protein_coding
description:
  Aquaporin Z 2; [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: OI25_1082
symbol: OI25_1082
gene_biotype: protein_coding
description:
  Bacterial regulatory s, luxR family protein; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: OI25_1092
symbol: ssb
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding family protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: OI25_1094
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: OI25_1096
symbol: OI25_1096
gene_biotype: protein_coding
description:
  tonB-siderophor: TonB-dependent siderophore receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: OI25_1097
symbol: OI25_1097
gene_biotype: protein_coding
description:
  pepSY-associated TM helix family protein; [S] COG3182 Uncharacterized iron-regulated membrane protein.


ensembl_gene_id: OI25_1098
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: OI25_11
symbol: OI25_11
gene_biotype: protein_coding
description:
  outer_NodT: efflux transporter, outer membrane factor (OMF) lipo, NodT family protein; [MU] COG1538 Outer membrane protein.


ensembl_gene_id: OI25_1101
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: OI25_1102
symbol: OI25_1102
gene_biotype: protein_coding
description:
  trkA-N domain protein; [P] COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: OI25_1103
symbol: OI25_1103
gene_biotype: protein_coding
description:
  kpsF: sugar isomerase, KpsF/GutQ family protein; [M] COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: OI25_1104
symbol: OI25_1104
gene_biotype: protein_coding
description:
  yrbI-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family protein; [R] COG1778 Low specificity phosphatase (HAD superfamily).


ensembl_gene_id: OI25_1105
symbol: lptC
gene_biotype: protein_coding
description:
  lptC_YrbK: LPS export ABC transporter periplasmic protein LptC; [S] COG3117 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_1106
symbol: lptA
gene_biotype: protein_coding
description:
  Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.


ensembl_gene_id: OI25_1107
symbol: lptB
gene_biotype: protein_coding
description:
  LPS_export_lptB: LPS export ABC transporter ATP-binding protein; [R] COG1137 ABC-type (unclassified) transport system, ATPase component.


ensembl_gene_id: OI25_1108
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: OI25_1110
symbol: OI25_1110
gene_biotype: protein_coding
description:
  Band 3 cytoplasmic domain protein; [GT] COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: OI25_1111
symbol: hprK
gene_biotype: protein_coding
description:
  HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).


ensembl_gene_id: OI25_1115
symbol: mutM
gene_biotype: protein_coding
description:
  DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: OI25_1117
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: OI25_1118
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: OI25_1120
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate diphosphokinase family protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: OI25_1121
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal protein L25, Ctc-form; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: OI25_1122
symbol: pth
gene_biotype: protein_coding
description:
  aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: OI25_1123
symbol: hisC
gene_biotype: protein_coding
description:
  hisC: histidinol-phosphate transaminase; [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: OI25_1125
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: OI25_1127
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: OI25_1129
symbol: OI25_1129
gene_biotype: protein_coding
description:
  Fumarylacetoacetate (FAA) hydrolase family protein; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: OI25_113
symbol: OI25_113
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: OI25_1130
symbol: OI25_1130
gene_biotype: protein_coding
description:
  Glycosyl transferase family, helical bundle domain protein; [E] COG0547 Anthranilate phosphoribosyltransferase.


ensembl_gene_id: OI25_1131
symbol: OI25_1131
gene_biotype: protein_coding
description:
  HMGL-like family protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).


ensembl_gene_id: OI25_1133
symbol: OI25_1133
gene_biotype: protein_coding
description:
  Outer membrane beta-barrel domain protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.


ensembl_gene_id: OI25_1134
symbol: rpoH
gene_biotype: protein_coding
description:
  Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: OI25_1136
symbol: OI25_1136
gene_biotype: protein_coding
description:
  Bacterial Cytochrome Ubiquinol Oxidase family protein; [C] COG1271 Cytochrome bd-type quinol oxidase, subunit 1.


ensembl_gene_id: OI25_1137
symbol: cydB
gene_biotype: protein_coding
description:
  cydB: cytochrome d ubiquinol oxidase, subunit II; [C] COG1294 Cytochrome bd-type quinol oxidase, subunit 2.


ensembl_gene_id: OI25_1139
symbol: nagE
gene_biotype: protein_coding
description:
  PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component; [G] COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.


ensembl_gene_id: OI25_114
symbol: OI25_114
gene_biotype: protein_coding
description:
  hpcH/HpaI aldolase/citrate lyase family protein; [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: OI25_1140
symbol: ptsP
gene_biotype: protein_coding
description:
  PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; [G] COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria).


ensembl_gene_id: OI25_1142
symbol: nagA
gene_biotype: protein_coding
description:
  nagA: N-acetylglucosamine-6-phosphate deacetylase; [G] COG1820 N-acetylglucosamine-6-phosphate deacetylase.


ensembl_gene_id: OI25_1144
symbol: OI25_1144
gene_biotype: protein_coding
description:
  Acetyltransferase domain protein; [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: OI25_1145
symbol: OI25_1145
gene_biotype: protein_coding
description:
  Lipo, YaeC family protein; [P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: OI25_1148
symbol: OI25_1148
gene_biotype: protein_coding
description:
  Redoxin family protein; [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: OI25_1149
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: OI25_1157
symbol: ctaD
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: OI25_1158
symbol: coxB
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: OI25_116
symbol: fusA-3
gene_biotype: protein_coding
description:
  Elongation factor G, domain IV family protein; [J] COG0480 Translation elongation factors (GTPases).


ensembl_gene_id: OI25_1160
symbol: bioC
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: OI25_1162
symbol: OI25_1162
gene_biotype: protein_coding
description:
  Macro domain protein; [R] COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: OI25_1163
symbol: trmL
gene_biotype: protein_coding
description:
  tRNA (cytidine(34)-2'-O)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: OI25_1164
symbol: gpsA
gene_biotype: protein_coding
description:
  NAD-dependent glycerol-3-phosphate dehydrogenase family protein; [C] COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: OI25_1165
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: OI25_1166
symbol: grxC
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: OI25_1168
symbol: gpmA
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: OI25_1169
symbol: OI25_1169
gene_biotype: protein_coding
description:
  Hypothetical protein; Prc: C-terminal processing peptidase family protein; [M] COG0793 Periplasmic protease; Belongs to the peptidase S41A family.


ensembl_gene_id: OI25_117
symbol: trpS
gene_biotype: protein_coding
description:
  trpS: tryptophan--tRNA ligase; [J] COG0180 Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: OI25_1170
symbol: OI25_1170
gene_biotype: protein_coding
description:
  thiF family protein; [H] COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: OI25_1171
symbol: ptsP-2
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: OI25_1172
symbol: OI25_1172
gene_biotype: protein_coding
description:
  PTS_HPr_: phosphocarrier, HPr family protein; [G] COG1925 Phosphotransferase system, HPr-related proteins.


ensembl_gene_id: OI25_1174
symbol: gshB
gene_biotype: protein_coding
description:
  Glut_syn: glutathione synthase; [HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: OI25_1178
symbol: OI25_1178
gene_biotype: protein_coding
description:
  Membrane fusogenic activity family protein; [S] COG2960 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_118
symbol: OI25_118
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [S] COG4461 Uncharacterized protein conserved in bacteria, putative lipoprotein.


ensembl_gene_id: OI25_1180
symbol: OI25_1180
gene_biotype: protein_coding
description:
  Autotrans_barl: outer membrane autotransporter barrel domain protein; [MU] COG3468 Type V secretory pathway, adhesin AidA.


ensembl_gene_id: OI25_1183
symbol: OI25_1183
gene_biotype: protein_coding
description:
  AAA domain family protein; [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: OI25_1185
symbol: dctA-2
gene_biotype: protein_coding
description:
  Dicarboxylate symporter family protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: OI25_1186
symbol: potA
gene_biotype: protein_coding
description:
  Polyamine ABC transporter, ATP-binding family protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: OI25_1187
symbol: OI25_1187
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: OI25_1188
symbol: OI25_1188
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [R] COG4132 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: OI25_1189
symbol: OI25_1189
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding family protein; [P] COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: OI25_1192
symbol: OI25_1192
gene_biotype: protein_coding
description:
  deoR-like helix-turn-helix domain protein; [KG] COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: OI25_1193
symbol: pNaS
gene_biotype: protein_coding
description:
  2a58: sodium-dependent inorganic phosphate (Pi) transporter family protein; [P] COG1283 Na+/phosphate symporter.


ensembl_gene_id: OI25_1194
symbol: OI25_1194
gene_biotype: protein_coding
description:
  HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, IB family protein; [E] COG0560 Phosphoserine phosphatase.


ensembl_gene_id: OI25_1195
symbol: OI25_1195
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [P] COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: OI25_1196
symbol: tauB
gene_biotype: protein_coding
description:
  ABC transporter family protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: OI25_1197
symbol: tauA
gene_biotype: protein_coding
description:
  taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein; [P] COG4521 ABC-type taurine transport system, periplasmic component.


ensembl_gene_id: OI25_1198
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: OI25_1199
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: OI25_1203
symbol: OI25_1203
gene_biotype: protein_coding
description:
  Aminotransferase class IV family protein; [EH] COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: OI25_1209
symbol: OI25_1209
gene_biotype: protein_coding
description:
  Mce related family protein; [Q] COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: OI25_1210
symbol: OI25_1210
gene_biotype: protein_coding
description:
  ABC transporter family protein; [Q] COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.


ensembl_gene_id: OI25_1211
symbol: OI25_1211
gene_biotype: protein_coding
description:
  [Q] COG0767 ABC-type transport system involved in resistance to organic solvents, permease component.


ensembl_gene_id: OI25_1212
symbol: OI25_1212
gene_biotype: protein_coding
description:
  birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase; [H] COG0340 Biotin-(acetyl-CoA carboxylase) ligase.


ensembl_gene_id: OI25_1213
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase, type III family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: OI25_1215
symbol: rfaE2
gene_biotype: protein_coding
description:
  Bifunctional protein RfaE, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.


ensembl_gene_id: OI25_1218
symbol: OI25_1218
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase/isomerase family protein; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: OI25_1219
symbol: OI25_1219
gene_biotype: protein_coding
description:
  Periplasmic binding domain protein; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: OI25_122
symbol: OI25_122
gene_biotype: protein_coding
description:
  Rieske [2Fe-2S] domain protein; [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: OI25_1225
symbol: OI25_1225
gene_biotype: protein_coding
description:
  Homocysteine S-methyltransferase family protein; [E] COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.


ensembl_gene_id: OI25_1226
symbol: metH
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: OI25_1232
symbol: OI25_1232
gene_biotype: protein_coding
description:
  Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: OI25_1233
symbol: OI25_1233
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding s, 5 Middle family protein; [E] COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: OI25_1234
symbol: OI25_1234
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase superfamily protein; [R] COG0491 Zn-dependent hydrolases, including glyoxylases.


ensembl_gene_id: OI25_1236
symbol: aceK
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase kinase/phosphatase family protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: OI25_1239
symbol: OI25_1239
gene_biotype: protein_coding
description:
  Short chain dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: OI25_1243
symbol: bioA
gene_biotype: protein_coding
description:
  bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase; [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: OI25_1244
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: OI25_1245
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: OI25_1246
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: OI25_1247
symbol: OI25_1247
gene_biotype: protein_coding
description:
  3a0106s03: sulfate ABC transporter, sulfate-binding family protein; [P] COG1613 ABC-type sulfate transport system, periplasmic component.


ensembl_gene_id: OI25_1249
symbol: OI25_1249
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein; [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: OI25_1258
symbol: OI25_1258
gene_biotype: protein_coding
description:
  Nitronate monooxygenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase.


ensembl_gene_id: OI25_1274
symbol: OI25_1274
gene_biotype: protein_coding
description:
  Hypothetical protein; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; [C] COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits.


ensembl_gene_id: OI25_1277
symbol: OI25_1277
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: OI25_1281
symbol: OI25_1281
gene_biotype: protein_coding
description:
  GGDEF: diguanylate cyclase domain protein; [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.


ensembl_gene_id: OI25_1282
symbol: OI25_1282
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: OI25_1284
symbol: OI25_1284
gene_biotype: protein_coding
description:
  rmlD substrate binding domain protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: OI25_1287
symbol: OI25_1287
gene_biotype: protein_coding
description:
  TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence domain protein; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: OI25_1288
symbol: OI25_1288
gene_biotype: protein_coding
description:
  [2Fe-2S] binding domain protein; [C] COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: OI25_1293
symbol: gmhA
gene_biotype: protein_coding
description:
  SIS domain protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: OI25_1294
symbol: OI25_1294
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: OI25_1295
symbol: rsmI
gene_biotype: protein_coding
description:
  16S rRNA (cytidine(1402)-2'-O)-methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: OI25_1296
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoA family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: OI25_13
symbol: emrB
gene_biotype: protein_coding
description:
  efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 family protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_1300
symbol: OI25_1300
gene_biotype: protein_coding
description:
  CDF: cation diffusion facilitator transporter family protein; [P] COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: OI25_1302
symbol: OI25_1302
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase family protein; [P] COG0748 Putative heme iron utilization protein.


ensembl_gene_id: OI25_1306
symbol: OI25_1306
gene_biotype: protein_coding
description:
  Receptor ligand binding region family protein; [E] COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: OI25_1308
symbol: OI25_1308
gene_biotype: protein_coding
description:
  Amidase family protein; [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: OI25_1309
symbol: OI25_1309
gene_biotype: protein_coding
description:
  High potential iron-sulfur family protein; Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria; Belongs to the high-potential iron-sulfur protein (HiPIP) family.


ensembl_gene_id: OI25_131
symbol: OI25_131
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase / NADH oxidase family protein; [C] COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: OI25_1316
symbol: OI25_1316
gene_biotype: protein_coding
description:
  Periplasmic binding domain protein; [G] COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: OI25_1317
symbol: ccmA
gene_biotype: protein_coding
description:
  ccmA: heme ABC exporter, ATP-binding protein CcmA; [G] COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: OI25_1321
symbol: OI25_1321
gene_biotype: protein_coding
description:
  Oxidoreductase NAD-binding domain protein; [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: OI25_1327
symbol: OI25_1327
gene_biotype: protein_coding
description:
  Molybdopterin-binding domain of aldehyde dehydrogenase family protein; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: OI25_1328
symbol: OI25_1328
gene_biotype: protein_coding
description:
  FAD binding domain in molybdopterin dehydrogenase family protein; [C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: OI25_1331
symbol: OI25_1331
gene_biotype: protein_coding
description:
  Carbon monoxide dehydrogenase subunit G family protein; [S] COG3427 Uncharacterized conserved protein.


ensembl_gene_id: OI25_1332
symbol: OI25_1332
gene_biotype: protein_coding
description:
  xdhC Rossmann domain protein; [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family.


ensembl_gene_id: OI25_1334
symbol: OI25_1334
gene_biotype: protein_coding
description:
  pepSY-associated TM helix family protein; [S] COG3295 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_1335
symbol: OI25_1335
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: OI25_1336
symbol: srkA
gene_biotype: protein_coding
description:
  Phosphotransferase enzyme family protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: OI25_1340
symbol: OI25_1340
gene_biotype: protein_coding
description:
  Aldo/keto reductase family protein; [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: OI25_1342
symbol: OI25_1342
gene_biotype: protein_coding
description:
  phytanoyl-CoA dioxygenase family protein; [Q] COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: OI25_1344
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: OI25_1345
symbol: OI25_1345
gene_biotype: protein_coding
description:
  Bacterial lipid A biosynthesis acyltransferase family protein; [M] COG1560 Lauroyl/myristoyl acyltransferase.


ensembl_gene_id: OI25_1346
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: OI25_1348
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: OI25_1349
symbol: OI25_1349
gene_biotype: protein_coding
description:
  Ribosomal L11 methyltransferase family protein; [R] COG1092 Predicted SAM-dependent methyltransferases.


ensembl_gene_id: OI25_135
symbol: OI25_135
gene_biotype: protein_coding
description:
  Hsp20/alpha crystallin family protein; [O] COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: OI25_1351
symbol: dksA
gene_biotype: protein_coding
description:
  RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: OI25_1352
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: OI25_1353
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: OI25_1354
symbol: OI25_1354
gene_biotype: protein_coding
description:
  Bacterial regulatory, Fis family protein; [TK] COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain.


ensembl_gene_id: OI25_1357
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: OI25_1358
symbol: OI25_1358
gene_biotype: protein_coding
description:
  HAD-SF-IA-v3: HAD hydrolase, IA, variant 3 family protein; [R] COG1011 Predicted hydrolase (HAD superfamily).


ensembl_gene_id: OI25_136
symbol: OI25_136
gene_biotype: protein_coding
description:
  Sigma-54 interaction domain protein; [O] COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: OI25_1360
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: OI25_1366
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: OI25_1367
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: OI25_1368
symbol: gatC
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: OI25_1369
symbol: OI25_1369
gene_biotype: protein_coding
description:
  mreB: cell shape determining, MreB/Mrl family protein; [D] COG1077 Actin-like ATPase involved in cell morphogenesis.


ensembl_gene_id: OI25_1372
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: OI25_1373
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: OI25_1377
symbol: queD
gene_biotype: protein_coding
description:
  queuosine_QueD: queuosine biosynthesis protein QueD; [H] COG0720 6-pyruvoyl-tetrahydropterin synthase.


ensembl_gene_id: OI25_1378
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM superfamily protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: OI25_1379
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: OI25_1381
symbol: OI25_1381
gene_biotype: protein_coding
description:
  Bacterial regulatory, Fis family protein; [T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: OI25_1382
symbol: OI25_1382
gene_biotype: protein_coding
description:
  HAMP domain protein; [T] COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.


ensembl_gene_id: OI25_1384
symbol: rsmB
gene_biotype: protein_coding
description:
  16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: OI25_1385
symbol: htpX
gene_biotype: protein_coding
description:
  Peptidase M48 family protein; [O] COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: OI25_1387
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: OI25_1388
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: OI25_1389
symbol: dprA
gene_biotype: protein_coding
description:
  dprA: DNA protecting protein DprA; [LU] COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: OI25_1393
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase family protein; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: OI25_1394
symbol: OI25_1394
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein; [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: OI25_1396
symbol: OI25_1396
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: OI25_1398
symbol: OI25_1398
gene_biotype: protein_coding
description:
  ygfB_yecA: yecA family protein; [R] COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA.


ensembl_gene_id: OI25_14
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine(55) synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: OI25_1402
symbol: OI25_1402
gene_biotype: protein_coding
description:
  FAD binding domain protein; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: OI25_1403
symbol: OI25_1403
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding s, 3 family protein; [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: OI25_1405
symbol: OI25_1405
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase family protein; [LKJ] COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: OI25_1407
symbol: cadR
gene_biotype: protein_coding
description:
  cadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator; [K] COG0789 Predicted transcriptional regulators.


ensembl_gene_id: OI25_1412
symbol: OI25_1412
gene_biotype: protein_coding
description:
  Ethanolamine ammonia-lyase light chain family protein; [E] COG4302 Ethanolamine ammonia-lyase, small subunit; Belongs to the EutC family.


ensembl_gene_id: OI25_1418
symbol: OI25_1418
gene_biotype: protein_coding
description:
  Resolvase, N terminal domain protein; [L] COG1961 Site-specific recombinases, DNA invertase Pin homologs.


ensembl_gene_id: OI25_1419
symbol: OI25_1419
gene_biotype: protein_coding
description:
  parB_part: ParB/RepB/Spo0J family partition domain protein; [K] COG1475 Predicted transcriptional regulators.


ensembl_gene_id: OI25_144
symbol: OI25_144
gene_biotype: protein_coding
description:
  RND_mfp: efflux transporter, RND family, MFP subunit; [M] COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: OI25_145
symbol: OI25_145
gene_biotype: protein_coding
description:
  acrB/AcrD/AcrF family protein; [V] COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: OI25_1455
symbol: OI25_1455
gene_biotype: protein_coding
description:
  PLD-like domain protein; [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: OI25_1456
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: OI25_1457
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: OI25_1458
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: OI25_1459
symbol: rpmH
gene_biotype: protein_coding
description:
  rpmH_bact: ribosomal protein L34; [J] COG0230 Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: OI25_1460
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: OI25_1461
symbol: yidC
gene_biotype: protein_coding
description:
  Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: OI25_1463
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: OI25_1469
symbol: OI25_1469
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat family protein; [NT] COG1352 Methylase of chemotaxis methyl-accepting proteins.


ensembl_gene_id: OI25_1472
symbol: cheB
gene_biotype: protein_coding
description:
  cheB methylesterase family protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: OI25_1474
symbol: OI25_1474
gene_biotype: protein_coding
description:
  HIT domain protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: OI25_1476
symbol: OI25_1476
gene_biotype: protein_coding
description:
  Acetyltransferase domain protein; [J] COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: OI25_1478
symbol: OI25_1478
gene_biotype: protein_coding
description:
  Dehydratase family protein; [EG] COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family.


ensembl_gene_id: OI25_1480
symbol: araG
gene_biotype: protein_coding
description:
  Arabinose import ATP-binding protein AraG; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.


ensembl_gene_id: OI25_1486
symbol: OI25_1486
gene_biotype: protein_coding
description:
  Ogt: methylated-DNA--[]-cysteine S-methyltransferase family protein; [L] COG0350 Methylated DNA-protein cysteine methyltransferase.


ensembl_gene_id: OI25_1487
symbol: OI25_1487
gene_biotype: protein_coding
description:
  hhH-GPD superbase excision DNA repair family protein; [L] COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.


ensembl_gene_id: OI25_1488
symbol: gshA-2
gene_biotype: protein_coding
description:
  Glu_cys_ligase: glutamate--cysteine ligase; [H] COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: OI25_1495
symbol: OI25_1495
gene_biotype: protein_coding
description:
  Type II secretion system (T2SS), M family protein; [U] COG3149 Type II secretory pathway, component PulM.


ensembl_gene_id: OI25_1496
symbol: gspL
gene_biotype: protein_coding
description:
  typeII_sec_gspL: type II secretion system protein L; [U] COG3297 Type II secretory pathway, component PulL.


ensembl_gene_id: OI25_1497
symbol: OI25_1497
gene_biotype: protein_coding
description:
  Type II secretion system (T2SS), K family protein; [U] COG3156 Type II secretory pathway, component PulK.


ensembl_gene_id: OI25_1498
symbol: OI25_1498
gene_biotype: protein_coding
description:
  Hypothetical protein; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein; [U] COG4795 Type II secretory pathway, component PulJ.


ensembl_gene_id: OI25_15
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: OI25_150
symbol: OI25_150
gene_biotype: protein_coding
description:
  HDOD domain protein; [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains.


ensembl_gene_id: OI25_1500
symbol: gspH
gene_biotype: protein_coding
description:
  typeII_sec_gspH: type II secretion system protein H; [NU] COG2165 Type II secretory pathway, pseudopilin PulG.


ensembl_gene_id: OI25_1501
symbol: gspG
gene_biotype: protein_coding
description:
  typeII_sec_gspG: type II secretion system protein G; [NU] COG2165 Type II secretory pathway, pseudopilin PulG.


ensembl_gene_id: OI25_1504
symbol: gspE
gene_biotype: protein_coding
description:
  Type II secretion system protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: OI25_1505
symbol: gspD
gene_biotype: protein_coding
description:
  type_II_gspD: type II secretion system protein D; [NU] COG1450 Type II secretory pathway, component PulD.


ensembl_gene_id: OI25_1506
symbol: OI25_1506
gene_biotype: protein_coding
description:
  Transglycosylase SLT domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: OI25_1508
symbol: OI25_1508
gene_biotype: protein_coding
description:
  Bacterial DNA-binding family protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: OI25_1509
symbol: mnmC
gene_biotype: protein_coding
description:
  tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: OI25_151
symbol: OI25_151
gene_biotype: protein_coding
description:
  GGDEF: diguanylate cyclase domain protein; [T] COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: OI25_1511
symbol: OI25_1511
gene_biotype: protein_coding
description:
  Carboxylate-amine ligase, YbdK family protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: OI25_1517
symbol: OI25_1517
gene_biotype: protein_coding
description:
  Hypothetical protein; Transcriptional regulatory, C terminal family protein; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: OI25_1524
symbol: mmsA
gene_biotype: protein_coding
description:
  MMSDH: methylmalonate-semialdehyde dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases.


ensembl_gene_id: OI25_1526
symbol: OI25_1526
gene_biotype: protein_coding
description:
  ABC transporter family protein; [E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: OI25_1527
symbol: OI25_1527
gene_biotype: protein_coding
description:
  ABC transporter family protein; [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: OI25_1529
symbol: OI25_1529
gene_biotype: protein_coding
description:
  [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_1530
symbol: OI25_1530
gene_biotype: protein_coding
description:
  [E] COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_1536
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: OI25_1537
symbol: rsmG
gene_biotype: protein_coding
description:
  16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: OI25_1538
symbol: OI25_1538
gene_biotype: protein_coding
description:
  4Fe-4S iron sulfur cluster binding s, NifH/frxC family protein; [D] COG1192 ATPases involved in chromosome partitioning.


ensembl_gene_id: OI25_1539
symbol: OI25_1539
gene_biotype: protein_coding
description:
  parB_part: ParB/RepB/Spo0J family partition domain protein; [K] COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: OI25_154
symbol: adc
gene_biotype: protein_coding
description:
  Putative acetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family.


ensembl_gene_id: OI25_1541
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: OI25_1542
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: OI25_1543
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: OI25_1544
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: OI25_1545
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: OI25_1546
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: OI25_1547
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: OI25_1548
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: OI25_155
symbol: OI25_155
gene_biotype: protein_coding
description:
  3A0103s03R: lysine-arginine-ornithine-binding periplasmic family protein; [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: OI25_1551
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: OI25_1552
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: OI25_1556
symbol: putA
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: OI25_1558
symbol: OI25_1558
gene_biotype: protein_coding
description:
  Iron-containing redox enzyme family protein; [H] COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C.


ensembl_gene_id: OI25_1560
symbol: OI25_1560
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate enzyme, central domain protein; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: OI25_1561
symbol: OI25_1561
gene_biotype: protein_coding
description:
  Sda_mono: L-serine ammonia-lyase; [E] COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: OI25_1563
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: OI25_1564
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: OI25_1565
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: OI25_1567
symbol: OI25_1567
gene_biotype: protein_coding
description:
  Hypothetical protein; Oxidoreductase family, C-terminal alpha/beta domain protein; [R] COG0673 Predicted dehydrogenases and related proteins.


ensembl_gene_id: OI25_1568
symbol: rep
gene_biotype: protein_coding
description:
  Hypothetical protein; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: OI25_158
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: OI25_1582
symbol: OI25_1582
gene_biotype: protein_coding
description:
  Ring hydroxylating alpha subunit family protein; [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: OI25_1583
symbol: OI25_1583
gene_biotype: protein_coding
description:
  neuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family protein; [R] COG0110 Acetyltransferase (isoleucine patch superfamily).


ensembl_gene_id: OI25_1588
symbol: OI25_1588
gene_biotype: protein_coding
description:
  Beta-eliminating lyase family protein; [M] COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: OI25_1589
symbol: OI25_1589
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat family protein; [O] COG3914 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family.


ensembl_gene_id: OI25_159
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: OI25_1591
symbol: OI25_1591
gene_biotype: protein_coding
description:
  Flagellar hook-associated family protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: OI25_1592
symbol: OI25_1592
gene_biotype: protein_coding
description:
  Hypothetical protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: OI25_1594
symbol: rpsU
gene_biotype: protein_coding
description:
  S21p: ribosomal protein S21; [J] COG0828 Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: OI25_1598
symbol: OI25_1598
gene_biotype: protein_coding
description:
  HAD-SF-IIB: HAD hydrolase, IIB family protein; [R] COG0561 Predicted hydrolases of the HAD superfamily.


ensembl_gene_id: OI25_16
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: OI25_160
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamate-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: OI25_1601
symbol: aqpZ
gene_biotype: protein_coding
description:
  MIP channel s family protein; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: OI25_1604
symbol: flhD
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator family protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: OI25_1605
symbol: flhC
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator family protein; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: OI25_1607
symbol: OI25_1607
gene_biotype: protein_coding
description:
  Membrane MotB of proton-channel complex MotA/MotB family protein; [N] COG1360 Flagellar motor protein.


ensembl_gene_id: OI25_1609
symbol: OI25_1609
gene_biotype: protein_coding
description:
  Signal transducing histidine kinase, homodimeric domain protein; [NT] COG0643 Chemotaxis protein histidine kinase and related kinases.


ensembl_gene_id: OI25_161
symbol: astA
gene_biotype: protein_coding
description:
  arg_catab_AstA: arginine N-succinyltransferase; [E] COG3138 Arginine/ornithine N-succinyltransferase beta subunit.


ensembl_gene_id: OI25_1612
symbol: OI25_1612
gene_biotype: protein_coding
description:
  cheR methyltransferase, SAM binding domain protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: OI25_1613
symbol: cheD
gene_biotype: protein_coding
description:
  cheD chemotactic sensory transduction family protein; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: OI25_1616
symbol: OI25_1616
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase, CheZ family protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: OI25_1619
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: OI25_162
symbol: aruF
gene_biotype: protein_coding
description:
  arg_AOST_alph: arginine/ornithine succinyltransferase, alpha subunit; [E] COG3138 Arginine/ornithine N-succinyltransferase beta subunit.


ensembl_gene_id: OI25_1620
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: OI25_1623
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor, FliA/WhiG family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: OI25_1627
symbol: flgM
gene_biotype: protein_coding
description:
  flgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM; [KNU] COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor).


ensembl_gene_id: OI25_1628
symbol: flgA
gene_biotype: protein_coding
description:
  flgA_cterm: flagella basal body P-ring formation protein FlgA; [NO] COG1261 Flagellar basal body P-ring biosynthesis protein.


ensembl_gene_id: OI25_1629
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: OI25_163
symbol: astC
gene_biotype: protein_coding
description:
  arg_catab_astC: succinylornithine transaminase family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: OI25_1630
symbol: flgC
gene_biotype: protein_coding
description:
  flgC: flagellar basal-body rod protein FlgC; [N] COG1558 Flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: OI25_1633
symbol: flgF
gene_biotype: protein_coding
description:
  flgF: flagellar basal-body rod protein FlgF; [N] COG4787 Flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: OI25_1634
symbol: flgF-2
gene_biotype: protein_coding
description:
  flgF: flagellar basal-body rod protein FlgF; [N] COG4786 Flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: OI25_1635
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring family protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: OI25_1636
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring family protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: OI25_1637
symbol: flgJ
gene_biotype: protein_coding
description:
  flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ; [NU] COG1705 Muramidase (flagellum-specific).


ensembl_gene_id: OI25_1638
symbol: ycgR
gene_biotype: protein_coding
description:
  pilZ domain protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: OI25_164
symbol: argR
gene_biotype: protein_coding
description:
  [K] COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: OI25_1640
symbol: flgL
gene_biotype: protein_coding
description:
  flagell_flgL: flagellar hook-associated protein 3; [N] COG1344 Flagellin and related hook-associated proteins.


ensembl_gene_id: OI25_1641
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: OI25_1642
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: OI25_1643
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: OI25_1645
symbol: fliN
gene_biotype: protein_coding
description:
  fliN: flagellar motor switch protein FliN; [NU] COG1886 Flagellar motor switch/type III secretory pathway protein.


ensembl_gene_id: OI25_1647
symbol: OI25_1647
gene_biotype: protein_coding
description:
  Flagellar basal body-associated FliL family protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: OI25_1650
symbol: fliI
gene_biotype: protein_coding
description:
  fliI_clade1: flagellar protein export ATPase FliI; [NU] COG1157 Flagellar biosynthesis/type III secretory pathway ATPase.


ensembl_gene_id: OI25_1651
symbol: OI25_1651
gene_biotype: protein_coding
description:
  Flagellar assembly FliH family protein; [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein.


ensembl_gene_id: OI25_1653
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: OI25_1654
symbol: fliE
gene_biotype: protein_coding
description:
  fliE: flagellar hook-basal body complex protein FliE; [NU] COG1677 Flagellar hook-basal body protein.


ensembl_gene_id: OI25_1658
symbol: OI25_1658
gene_biotype: protein_coding
description:
  flhB HrpN YscU SpaS family protein; [S] COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.


ensembl_gene_id: OI25_166
symbol: OI25_166
gene_biotype: protein_coding
description:
  HEQRo_perm_3TM: amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein; [E] COG4160 ABC-type arginine/histidine transport system, permease component.


ensembl_gene_id: OI25_1660
symbol: OI25_1660
gene_biotype: protein_coding
description:
  Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein; [I] COG1960 Acyl-CoA dehydrogenases.


ensembl_gene_id: OI25_1661
symbol: OI25_1661
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase family protein; [E] COG2303 Choline dehydrogenase and related flavoproteins.


ensembl_gene_id: OI25_1662
symbol: OI25_1662
gene_biotype: protein_coding
description:
  ompA family protein; [M] COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: OI25_1664
symbol: OI25_1664
gene_biotype: protein_coding
description:
  Glycosyltransferase like 2 family protein; [M] COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: OI25_1665
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: OI25_1667
symbol: metF
gene_biotype: protein_coding
description:
  Fadh2: methylenetetrahydrofolate reductase [NAD(P)H]; [E] COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: OI25_167
symbol: OI25_167
gene_biotype: protein_coding
description:
  HEQRo_perm_3TM: amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein; [E] COG4215 ABC-type arginine transport system, permease component.


ensembl_gene_id: OI25_1670
symbol: OI25_1670
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [EP] COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: OI25_1671
symbol: OI25_1671
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [EP] COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: OI25_1672
symbol: dppD
gene_biotype: protein_coding
description:
  Hypothetical protein; oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein; [EP] COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_1673
symbol: OI25_1673
gene_biotype: protein_coding
description:
  Hypothetical protein; oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein; [E] COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_1678
symbol: pxpA
gene_biotype: protein_coding
description:
  lamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: OI25_168
symbol: OI25_168
gene_biotype: protein_coding
description:
  Patatin-like phospholipase family protein; [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily.


ensembl_gene_id: OI25_1681
symbol: OI25_1681
gene_biotype: protein_coding
description:
  Winged helix DNA-binding domain protein; [K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family).


ensembl_gene_id: OI25_1682
symbol: OI25_1682
gene_biotype: protein_coding
description:
  MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase; [H] COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: OI25_1683
symbol: OI25_1683
gene_biotype: protein_coding
description:
  [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: OI25_1684
symbol: OI25_1684
gene_biotype: protein_coding
description:
  3-beta hydroxysteroid dehydrogenase/isomerase family protein; [MG] COG0702 Predicted nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: OI25_1685
symbol: OI25_1685
gene_biotype: protein_coding
description:
  Hypothetical protein; Glutathione S-transferase, N-terminal domain protein; [O] COG0625 Glutathione S-transferase.


ensembl_gene_id: OI25_1686
symbol: cca
gene_biotype: protein_coding
description:
  Poly A polymerase head domain protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: OI25_1692
symbol: OI25_1692
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine-dependent methyltransferase family protein; [S] COG1565 Uncharacterized conserved protein.


ensembl_gene_id: OI25_1695
symbol: ttcA
gene_biotype: protein_coding
description:
  PP-loop family protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: OI25_1696
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: OI25_1697
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: OI25_17
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor; Participates in both transcription termination and antitermination.


ensembl_gene_id: OI25_1701
symbol: OI25_1701
gene_biotype: protein_coding
description:
  Hypothetical protein; Glutathione S-transferase, N-terminal domain protein; [O] COG0625 Glutathione S-transferase; Belongs to the GST superfamily.


ensembl_gene_id: OI25_171
symbol: OI25_171
gene_biotype: protein_coding
description:
  ssuA_fam: ABC transporter, substrate-binding, aliphatic sulfonates family protein; [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: OI25_1712
symbol: OI25_1712
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: OI25_1717
symbol: OI25_1717
gene_biotype: protein_coding
description:
  NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase family protein; [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: OI25_1722
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: OI25_1726
symbol: pyrE
gene_biotype: protein_coding
description:
  Phosphoribosyl transferase domain protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: OI25_1728
symbol: OI25_1728
gene_biotype: protein_coding
description:
  Malic enzyme, NAD binding domain protein; [C] COG0281 Malic enzyme; Belongs to the malic enzymes family.


ensembl_gene_id: OI25_1731
symbol: hppD
gene_biotype: protein_coding
description:
  4HPPD: 4-hydroxyphenylpyruvate dioxygenase; [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.


ensembl_gene_id: OI25_1733
symbol: OI25_1733
gene_biotype: protein_coding
description:
  Acetyltransferase family protein; [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: OI25_1736
symbol: paaK
gene_biotype: protein_coding
description:
  2Fe-2S iron-sulfur cluster binding domain protein; [C] COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: OI25_1737
symbol: paaJ
gene_biotype: protein_coding
description:
  PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit; [R] COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.


ensembl_gene_id: OI25_174
symbol: OI25_174
gene_biotype: protein_coding
description:
  Cysteine dioxygenase type I family protein; [R] COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily.


ensembl_gene_id: OI25_1741
symbol: OI25_1741
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase family protein; [R] COG2509 Uncharacterized FAD-dependent dehydrogenases.


ensembl_gene_id: OI25_1742
symbol: OI25_1742
gene_biotype: protein_coding
description:
  GDSL-like Lipase/Acylhydrolase family protein; [E] COG2755 Lysophospholipase L1 and related esterases.


ensembl_gene_id: OI25_1751
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: OI25_1753
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: OI25_1754
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antiterminator; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: OI25_1755
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: OI25_1756
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: OI25_1757
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal L10 family protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: OI25_1758
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: OI25_1759
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: OI25_176
symbol: OI25_176
gene_biotype: protein_coding
description:
  Hypothetical protein; Class II Aldolase and Adducin N-terminal domain protein; [G] COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: OI25_1760
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: OI25_1762
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: OI25_1763
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: OI25_1764
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: OI25_1766
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: OI25_1767
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: OI25_1769
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal L23 family protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: OI25_177
symbol: OI25_177
gene_biotype: protein_coding
description:
  Luciferase-like monooxygenase family protein; [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: OI25_1770
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: OI25_1771
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: OI25_1772
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: OI25_1773
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: OI25_1774
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: OI25_1775
symbol: rpmC
gene_biotype: protein_coding
description:
  L29: ribosomal protein L29; [J] COG0255 Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: OI25_1776
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: OI25_1777
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: OI25_1778
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: OI25_1779
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal L5 family protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: OI25_1780
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal S14p/S29e family protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: OI25_1781
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal S8 family protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: OI25_1782
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: OI25_1783
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: OI25_1784
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: OI25_1786
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: OI25_1787
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: OI25_1788
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: OI25_1789
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: OI25_179
symbol: OI25_179
gene_biotype: protein_coding
description:
  Oxido_grp_1: luciferase oxidoreductase, group 1 family protein; [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: OI25_1790
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: OI25_1791
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: OI25_1792
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: OI25_1795
symbol: dsbD
gene_biotype: protein_coding
description:
  Cytochrome C biogenesis transmembrane region family protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: OI25_1797
symbol: ysxC
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: OI25_18
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: OI25_1800
symbol: ccsB
gene_biotype: protein_coding
description:
  cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB; [O] COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component.


ensembl_gene_id: OI25_1801
symbol: msrP
gene_biotype: protein_coding
description:
  Oxidoreductase molybdopterin binding domain protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being a [...]


ensembl_gene_id: OI25_1802
symbol: msrQ
gene_biotype: protein_coding
description:
  Ferric reductase like transmembrane component family protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the red [...]


ensembl_gene_id: OI25_1803
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: OI25_1804
symbol: cyaY
gene_biotype: protein_coding
description:
  Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: OI25_1805
symbol: OI25_1805
gene_biotype: protein_coding
description:
  PBP_1a_fam: penicillin-binding, 1A family protein; [M] COG5009 Membrane carboxypeptidase/penicillin-binding protein.


ensembl_gene_id: OI25_1809
symbol: pilQ
gene_biotype: protein_coding
description:
  IV_pilus_PilQ: type IV pilus secretin PilQ family protein; [U] COG4796 Type II secretory pathway, component HofQ.


ensembl_gene_id: OI25_181
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: OI25_1810
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase family protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: OI25_1811
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: OI25_1812
symbol: dgt
gene_biotype: protein_coding
description:
  dGTP_triPase: dGTPase family protein; [F] COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: OI25_1817
symbol: gltD
gene_biotype: protein_coding
description:
  Glutamate synthase, NADH/NADPH, small subunit domain protein; [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: OI25_1818
symbol: OI25_1818
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).


ensembl_gene_id: OI25_1822
symbol: ompR
gene_biotype: protein_coding
description:
  [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: OI25_183
symbol: pdxY
gene_biotype: protein_coding
description:
  Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: OI25_1832
symbol: OI25_1832
gene_biotype: protein_coding
description:
  ABC transporter family protein; [R] COG4178 ABC-type uncharacterized transport system, permease and ATPase components.


ensembl_gene_id: OI25_1833
symbol: OI25_1833
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase family protein; [E] COG0665 Glycine/D-amino acid oxidases (deaminating).


ensembl_gene_id: OI25_1834
symbol: thiS
gene_biotype: protein_coding
description:
  thiS: thiamine biosynthesis protein ThiS; [H] COG2104 Sulfur transfer protein involved in thiamine biosynthesis.


ensembl_gene_id: OI25_1835
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis ThiG family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: OI25_1836
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine monophosphate synthase/TENI family protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: OI25_1839
symbol: mlaD
gene_biotype: protein_coding
description:
  OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD; [Q] COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: OI25_1841
symbol: OI25_1841
gene_biotype: protein_coding
description:
  Toluene tolerance, Ttg2 family protein; [Q] COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.


ensembl_gene_id: OI25_1844
symbol: OI25_1844
gene_biotype: protein_coding
description:
  ABC-2 type transporter family protein; [V] COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: OI25_1845
symbol: OI25_1845
gene_biotype: protein_coding
description:
  bolA-like family protein; [K] COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family.


ensembl_gene_id: OI25_1846
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: OI25_1847
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: OI25_1848
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: OI25_1852
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: OI25_1854
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: OI25_1855
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase family protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: OI25_1856
symbol: hisE
gene_biotype: protein_coding
description:
  histidine_hisI: phosphoribosyl-ATP diphosphatase; [E] COG0140 Phosphoribosyl-ATP pyrophosphohydrolase.


ensembl_gene_id: OI25_1858
symbol: OI25_1858
gene_biotype: protein_coding
description:
  Hypothetical protein; Scavenger mRNA decapping enzyme C-term binding family protein; [FGR] COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: OI25_1859
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine-targeting translocase, TatA/E family protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: OI25_1860
symbol: tatB
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: OI25_1861
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: OI25_1862
symbol: OI25_1862
gene_biotype: protein_coding
description:
  degP_htrA_DO: peptidase Do family protein; [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: OI25_1864
symbol: petA
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: OI25_1865
symbol: OI25_1865
gene_biotype: protein_coding
description:
  Hypothetical protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: OI25_1870
symbol: OI25_1870
gene_biotype: protein_coding
description:
  Methyltransferase small domain protein; [J] COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily.


ensembl_gene_id: OI25_1883
symbol: OI25_1883
gene_biotype: protein_coding
description:
  Catalytic LigB subunit of aromatic ring-opening dioxygenase family protein; [S] COG3384 Uncharacterized conserved protein.


ensembl_gene_id: OI25_1884
symbol: ubiX
gene_biotype: protein_coding
description:
  Polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylase family protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: OI25_1885
symbol: grxD
gene_biotype: protein_coding
description:
  Monothiol glutaredoxin, Grx4 family; [O] COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: OI25_1886
symbol: prmC
gene_biotype: protein_coding
description:
  protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: OI25_1887
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: OI25_1888
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: OI25_1891
symbol: OI25_1891
gene_biotype: protein_coding
description:
  Hypothetical protein; creatinase/Prolidase N-terminal domain protein; [E] COG0006 Xaa-Pro aminopeptidase.


ensembl_gene_id: OI25_1894
symbol: ccmA-2
gene_biotype: protein_coding
description:
  ccmA: heme ABC exporter, ATP-binding protein CcmA; [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: OI25_1895
symbol: ugpC
gene_biotype: protein_coding
description:
  ABC transporter family protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: OI25_1896
symbol: ugpE
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: OI25_1897
symbol: OI25_1897
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [G] COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: OI25_1898
symbol: OI25_1898
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding family protein; [G] COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: OI25_1899
symbol: ychF
gene_biotype: protein_coding
description:
  50S ribosome-binding GTPase family protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: OI25_19
symbol: OI25_19
gene_biotype: protein_coding
description:
  Pseudouridine synthase family protein; [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: OI25_1905
symbol: OI25_1905
gene_biotype: protein_coding
description:
  50S ribosome-binding GTPase family protein; [J] COG0012 Predicted GTPase, probable translation factor.


ensembl_gene_id: OI25_1906
symbol: OI25_1906
gene_biotype: protein_coding
description:
  ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: OI25_1907
symbol: OI25_1907
gene_biotype: protein_coding
description:
  DSBA-like thioredoxin domain protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: OI25_1909
symbol: azoR
gene_biotype: protein_coding
description:
  NADPH-dependent FMN reductase family protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: OI25_1910
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: OI25_1913
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: OI25_1914
symbol: OI25_1914
gene_biotype: protein_coding
description:
  trpG_papA: glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein; [EH] COG0512 Anthranilate/para-aminobenzoate synthases component II.


ensembl_gene_id: OI25_1915
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: OI25_1916
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: OI25_192
symbol: hutF
gene_biotype: protein_coding
description:
  hutF: formiminoglutamate deiminase; [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: OI25_1921
symbol: paaF
gene_biotype: protein_coding
description:
  phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: OI25_1922
symbol: paaD
gene_biotype: protein_coding
description:
  paaD: phenylacetic acid degradation protein PaaD; [Q] COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: OI25_1923
symbol: paaB
gene_biotype: protein_coding
description:
  paaB1: phenylacetate degradation putative enoyl-CoA hydratase PaaB; [I] COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: OI25_1924
symbol: pcaF
gene_biotype: protein_coding
description:
  pcaF: 3-oxoadipyl-CoA thiolase; [I] COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: OI25_1925
symbol: paaN
gene_biotype: protein_coding
description:
  paaN_2: phenylacetic acid degradation protein paaN; [C] COG1012 NAD-dependent aldehyde dehydrogenases.


ensembl_gene_id: OI25_1932
symbol: OI25_1932
gene_biotype: protein_coding
description:
  Amidohydrolases: amidohydrolase family protein; [R] COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase.


ensembl_gene_id: OI25_1933
symbol: OI25_1933
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase Fe4S4 domain protein; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: OI25_1936
symbol: coq7
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis COQ7 family protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: OI25_1937
symbol: mraZ
gene_biotype: protein_coding
description:
  mraZ family protein; [S] COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: OI25_1938
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: OI25_1939
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: OI25_1940
symbol: ftsI
gene_biotype: protein_coding
description:
  Penicillin binding transpeptidase domain protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.


ensembl_gene_id: OI25_1941
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl-tripeptide synthetase family protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: OI25_1942
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase family protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: OI25_1943
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: OI25_1944
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: OI25_1945
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: OI25_1946
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: OI25_1948
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase family protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: OI25_1949
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division FtsQ family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: OI25_1950
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: OI25_1951
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: OI25_1952
symbol: OI25_1952
gene_biotype: protein_coding
description:
  ahpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: OI25_1953
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: OI25_1955
symbol: ltrA
gene_biotype: protein_coding
description:
  group_II_RT_mat: group II intron reverse transcriptase/maturase; [L] COG3344 Retron-type reverse transcriptase.


ensembl_gene_id: OI25_1956
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: OI25_1957
symbol: argJ
gene_biotype: protein_coding
description:
  Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: OI25_1959
symbol: OI25_1959
gene_biotype: protein_coding
description:
  NUDIX domain protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: OI25_1960
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: OI25_1961
symbol: zapD
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: OI25_1962
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: OI25_1963
symbol: OI25_1963
gene_biotype: protein_coding
description:
  Type IV leader peptidase family protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: OI25_1964
symbol: OI25_1964
gene_biotype: protein_coding
description:
  Type II secretion system (T2SS), F family protein; [NU] COG1459 Type II secretory pathway, component PulF.


ensembl_gene_id: OI25_1965
symbol: OI25_1965
gene_biotype: protein_coding
description:
  Type II/IV secretion system family protein; [NU] COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: OI25_1968
symbol: OI25_1968
gene_biotype: protein_coding
description:
  Polyprenyl synthetase family protein; [H] COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: OI25_1969
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: OI25_1970
symbol: rpmA
gene_biotype: protein_coding
description:
  L27: ribosomal protein L27; [J] COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: OI25_1971
symbol: cgtA
gene_biotype: protein_coding
description:
  Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: OI25_1972
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: OI25_1974
symbol: rppH
gene_biotype: protein_coding
description:
  NUDIX domain protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: OI25_1975
symbol: proS
gene_biotype: protein_coding
description:
  proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]


ensembl_gene_id: OI25_1978
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: OI25_1979
symbol: OI25_1979
gene_biotype: protein_coding
description:
  Cytochrome C assembly family protein; [R] COG4137 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: OI25_198
symbol: OI25_198
gene_biotype: protein_coding
description:
  3-beta hydroxysteroid dehydrogenase/isomerase family protein; [MG] COG0451 Nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: OI25_1981
symbol: OI25_1981
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase family protein; [V] COG3023 Negative regulator of beta-lactamase expression.


ensembl_gene_id: OI25_1982
symbol: OI25_1982
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: OI25_1983
symbol: OI25_1983
gene_biotype: protein_coding
description:
  Ribonucleotide reductase, small chain family protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: OI25_1988
symbol: tpx
gene_biotype: protein_coding
description:
  ahpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: OI25_1990
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: OI25_1991
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: OI25_1992
symbol: accB
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: OI25_1993
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: OI25_1996
symbol: mpl
gene_biotype: protein_coding
description:
  L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: OI25_1999
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: OI25_20
symbol: scpB
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: OI25_2000
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: OI25_2003
symbol: OI25_2003
gene_biotype: protein_coding
description:
  Thiamine monophosphate synthase/TENI family protein; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: OI25_2006
symbol: araG-2
gene_biotype: protein_coding
description:
  ABC transporter family protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.


ensembl_gene_id: OI25_2011
symbol: pyrF
gene_biotype: protein_coding
description:
  pyrF_sub2: orotidine 5'-phosphate decarboxylase; [F] COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: OI25_2013
symbol: OI25_2013
gene_biotype: protein_coding
description:
  pncC_: amidohydrolase, PncC family domain protein; [R] COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: OI25_2014
symbol: OI25_2014
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A family protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: OI25_2015
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: OI25_2019
symbol: OI25_2019
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmE family protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: OI25_202
symbol: OI25_202
gene_biotype: protein_coding
description:
  Bacterial regulatory s, luxR family protein; [K] COG2771 DNA-binding HTH domain-containing proteins.


ensembl_gene_id: OI25_2021
symbol: speE
gene_biotype: protein_coding
description:
  Spermine/spermidine synthase family protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.


ensembl_gene_id: OI25_2022
symbol: tkt
gene_biotype: protein_coding
description:
  Transketolase; Tktlase_bact: transketolase; [G] COG0021 Transketolase; Belongs to the transketolase family.


ensembl_gene_id: OI25_2023
symbol: gap
gene_biotype: protein_coding
description:
  GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I; [G] COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: OI25_2025
symbol: OI25_2025
gene_biotype: protein_coding
description:
  Sodium:dicarboxylate symporter family protein; [C] COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: OI25_2027
symbol: allA
gene_biotype: protein_coding
description:
  Ureidoglycolate hydrolase family protein; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.


ensembl_gene_id: OI25_2028
symbol: fur
gene_biotype: protein_coding
description:
  Ferric uptake regulator family protein; [P] COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: OI25_2029
symbol: bamE
gene_biotype: protein_coding
description:
  smpA / OmlA family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: OI25_2030
symbol: dapB
gene_biotype: protein_coding
description:
  4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: OI25_2033
symbol: leuS
gene_biotype: protein_coding
description:
  leuS_bact: leucine--tRNA ligase; [J] COG0495 Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: OI25_2034
symbol: lptE
gene_biotype: protein_coding
description:
  Lipopolysaccharide-assembly family protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.


ensembl_gene_id: OI25_2036
symbol: proA
gene_biotype: protein_coding
description:
  Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: OI25_2038
symbol: OI25_2038
gene_biotype: protein_coding
description:
  Coiled stalk of trimeric autotransporter adhesin family protein; [UW] COG5295 Autotransporter adhesin.


ensembl_gene_id: OI25_2040
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: OI25_2041
symbol: eda
gene_biotype: protein_coding
description:
  Eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein; [G] COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: OI25_2042
symbol: OI25_2042
gene_biotype: protein_coding
description:
  gntP: transporter, gluconate:H+ symporter family protein; [GE] COG2610 H+/gluconate symporter and related permeases.


ensembl_gene_id: OI25_2043
symbol: OI25_2043
gene_biotype: protein_coding
description:
  Therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family protein; [G] COG3265 Gluconate kinase.


ensembl_gene_id: OI25_2045
symbol: purB
gene_biotype: protein_coding
description:
  purB: adenylosuccinate lyase; [F] COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: OI25_2047
symbol: OI25_2047
gene_biotype: protein_coding
description:
  glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: OI25_2048
symbol: OI25_2048
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding s, 3 family protein; [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: OI25_2049
symbol: OI25_2049
gene_biotype: protein_coding
description:
  HEQRo_perm_3TM: amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein; [E] COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: OI25_2051
symbol: artP
gene_biotype: protein_coding
description:
  ABC transporter family protein; [E] COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: OI25_2052
symbol: OI25_2052
gene_biotype: protein_coding
description:
  Glutamine amidotransferases class-II family protein; [R] COG0121 Predicted glutamine amidotransferase.


ensembl_gene_id: OI25_2055
symbol: OI25_2055
gene_biotype: protein_coding
description:
  osmC-like family protein; [O] COG1765 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: OI25_2060
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: OI25_2063
symbol: anmK
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: OI25_2064
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: OI25_2065
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: OI25_2067
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: OI25_2068
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: OI25_2070
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: OI25_2072
symbol: purH
gene_biotype: protein_coding
description:
  purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; [F] COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: OI25_2073
symbol: OI25_2073
gene_biotype: protein_coding
description:
  Bacterial regulatory, Fis family protein; [KL] COG2901 Factor for inversion stimulation Fis, transcriptional activator; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: OI25_2074
symbol: dusB
gene_biotype: protein_coding
description:
  TIM-barrel, nifR3 family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: OI25_2076
symbol: OI25_2076
gene_biotype: protein_coding
description:
  Hypothetical protein; Aminopeptidase P, N-terminal domain protein; [E] COG0006 Xaa-Pro aminopeptidase; Belongs to the peptidase M24B family.


ensembl_gene_id: OI25_2078
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: OI25_2080
symbol: OI25_2080
gene_biotype: protein_coding
description:
  chaC-like family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: OI25_2081
symbol: ybeY
gene_biotype: protein_coding
description:
  Putative rRNA maturation factor YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: OI25_2082
symbol: OI25_2082
gene_biotype: protein_coding
description:
  phoH-like family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase.


ensembl_gene_id: OI25_2083
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: OI25_2088
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: OI25_2089
symbol: OI25_2089
gene_biotype: protein_coding
description:
  HAD-SF-IA-v3: HAD hydrolase, IA, variant 3 family protein; [R] COG0637 Predicted phosphatase/phosphohexomutase.


ensembl_gene_id: OI25_2090
symbol: OI25_2090
gene_biotype: protein_coding
description:
  MIP: MIP channel s family protein; [G] COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: OI25_2091
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: OI25_2092
symbol: OI25_2092
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase family protein; [C] COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: OI25_21
symbol: OI25_21
gene_biotype: protein_coding
description:
  cys/Met metabolism PLP-dependent enzyme family protein; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.


ensembl_gene_id: OI25_2101
symbol: rhlE
gene_biotype: protein_coding
description:
  Hypothetical protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: OI25_2102
symbol: OI25_2102
gene_biotype: protein_coding
description:
  hlyIII: channel, hemolysin III family protein; [R] COG1272 Predicted membrane protein, hemolysin III homolog.


ensembl_gene_id: OI25_2110
symbol: OI25_2110
gene_biotype: protein_coding
description:
  Hypothetical protein; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain protein; [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: OI25_2114
symbol: OI25_2114
gene_biotype: protein_coding
description:
  phn_lysR: aminoethylphosphonate catabolism associated LysR transcriptional regulator family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: OI25_2123
symbol: recA
gene_biotype: protein_coding
description:
  Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: OI25_2126
symbol: sucC
gene_biotype: protein_coding
description:
  succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: OI25_2127
symbol: sucD
gene_biotype: protein_coding
description:
  succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: OI25_2128
symbol: OI25_2128
gene_biotype: protein_coding
description:
  R_switched_YjbE: integral membrane, YjbE family protein; [P] COG0861 Membrane protein TerC, possibly involved in tellurium resistance.


ensembl_gene_id: OI25_2129
symbol: OI25_2129
gene_biotype: protein_coding
description:
  Hypothetical protein; IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain protein; [NU] COG4969 Tfp pilus assembly protein, major pilin PilA.


ensembl_gene_id: OI25_2131
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: OI25_2136
symbol: waaF
gene_biotype: protein_coding
description:
  heptsyl_trn_II: lipopolysaccharide heptosyltransferase II; [M] COG0859 ADP-heptose:LPS heptosyltransferase.


ensembl_gene_id: OI25_2138
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: OI25_2139
symbol: OI25_2139
gene_biotype: protein_coding
description:
  azlC family protein; [E] COG1296 Predicted branched-chain amino acid permease (azaleucine resistance).


ensembl_gene_id: OI25_2143
symbol: fba
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: OI25_2144
symbol: purC
gene_biotype: protein_coding
description:
  purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase; [F] COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: OI25_2145
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: OI25_2146
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: OI25_2147
symbol: OI25_2147
gene_biotype: protein_coding
description:
  tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: OI25_2150
symbol: dacB
gene_biotype: protein_coding
description:
  PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; [M] COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4).


ensembl_gene_id: OI25_2157
symbol: OI25_2157
gene_biotype: protein_coding
description:
  Helix-turn-helix domain protein; [K] COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: OI25_2161
symbol: OI25_2161
gene_biotype: protein_coding
description:
  2A0602: RND transporter, hydrophobe/amphiphile efflux-1 family protein; [V] COG0841 Cation/multidrug efflux pump.


ensembl_gene_id: OI25_2164
symbol: OI25_2164
gene_biotype: protein_coding
description:
  Hypothetical protein; FGGY family of carbohydrate kinase, N-terminal domain protein; [G] COG1070 Sugar (pentulose and hexulose) kinases.


ensembl_gene_id: OI25_2165
symbol: OI25_2165
gene_biotype: protein_coding
description:
  adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; [C] COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: OI25_2166
symbol: OI25_2166
gene_biotype: protein_coding
description:
  ABC 3 transport family protein; [P] COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.


ensembl_gene_id: OI25_2169
symbol: OI25_2169
gene_biotype: protein_coding
description:
  Periplasmic solute binding family protein; [P] COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: OI25_2173
symbol: OI25_2173
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [G] COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: OI25_2175
symbol: OI25_2175
gene_biotype: protein_coding
description:
  ABC transporter family protein; [G] COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_2176
symbol: OI25_2176
gene_biotype: protein_coding
description:
  Putative sugar-binding domain protein; [K] COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain.


ensembl_gene_id: OI25_2178
symbol: OI25_2178
gene_biotype: protein_coding
description:
  Mannitol dehydrogenase Rossmann domain protein; [G] COG0246 Mannitol-1-phosphate/altronate dehydrogenases.


ensembl_gene_id: OI25_218
symbol: OI25_218
gene_biotype: protein_coding
description:
  Permease for cytosine/purine, uracil, thiamine, allantoin family protein; [F] COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: OI25_2181
symbol: rbsA
gene_biotype: protein_coding
description:
  ABC transporter family protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: OI25_2183
symbol: OI25_2183
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase family protein; [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: OI25_2184
symbol: OI25_2184
gene_biotype: protein_coding
description:
  Hypothetical protein; FGGY family of carbohydrate kinase, N-terminal domain protein; [G] COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family.


ensembl_gene_id: OI25_2187
symbol: OI25_2187
gene_biotype: protein_coding
description:
  Hemolysin secretion/activation ShlB/FhaC/HecB family protein; [U] COG2831 Hemolysin activation/secretion protein.


ensembl_gene_id: OI25_2192
symbol: OI25_2192
gene_biotype: protein_coding
description:
  Hypothetical protein; adhes_NPXG: filamentous hemagglutinin family N-terminal domain protein; [U] COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: OI25_2193
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: OI25_2194
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: OI25_2195
symbol: kynB
gene_biotype: protein_coding
description:
  Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation.


ensembl_gene_id: OI25_2197
symbol: OI25_2197
gene_biotype: protein_coding
description:
  Flavin reductase like domain protein; [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: OI25_2198
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: OI25_220
symbol: OI25_220
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [C] COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: OI25_2200
symbol: OI25_2200
gene_biotype: protein_coding
description:
  Methyltransferase small domain protein; [M] COG2230 Cyclopropane fatty acid synthase and related methyltransferases.


ensembl_gene_id: OI25_2201
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: OI25_2202
symbol: OI25_2202
gene_biotype: protein_coding
description:
  thiF family protein; [H] COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1.


ensembl_gene_id: OI25_2207
symbol: OI25_2207
gene_biotype: protein_coding
description:
  T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE; [R] COG0802 Predicted ATPase or kinase.


ensembl_gene_id: OI25_2208
symbol: queG
gene_biotype: protein_coding
description:
  Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: OI25_221
symbol: OI25_221
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: OI25_2210
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: OI25_2212
symbol: OI25_2212
gene_biotype: protein_coding
description:
  aminoacyl-tRNA editing domain protein; [S] COG2606 Uncharacterized conserved protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: OI25_2213
symbol: plsY
gene_biotype: protein_coding
description:
  Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: OI25_2214
symbol: OI25_2214
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [S] COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family.


ensembl_gene_id: OI25_2216
symbol: argG
gene_biotype: protein_coding
description:
  argG: argininosuccinate synthase; [E] COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: OI25_2217
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: OI25_2218
symbol: OI25_2218
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: OI25_2220
symbol: mviN
gene_biotype: protein_coding
description:
  Murein biosynthesis integral membrane protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: OI25_2223
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: OI25_2224
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: OI25_2225
symbol: OI25_2225
gene_biotype: protein_coding
description:
  Trm112p-like family protein; [S] COG2835 Uncharacterized conserved protein; Belongs to the UPF0434 family.


ensembl_gene_id: OI25_2226
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: OI25_2227
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: OI25_2228
symbol: OI25_2228
gene_biotype: protein_coding
description:
  Iron/manganese superoxide dismutase, alpha-hairpin domain protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: OI25_2235
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: OI25_2237
symbol: OI25_2237
gene_biotype: protein_coding
description:
  sigma70-ECF: RNA polymerase sigma factor, sigma-70 family protein; [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.


ensembl_gene_id: OI25_2239
symbol: OI25_2239
gene_biotype: protein_coding
description:
  Aminotransferase class I and II family protein; [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: OI25_224
symbol: OI25_224
gene_biotype: protein_coding
description:
  AMP-binding enzyme family protein; [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: OI25_2242
symbol: OI25_2242
gene_biotype: protein_coding
description:
  coA-transferase III family protein; [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: OI25_2247
symbol: nikE
gene_biotype: protein_coding
description:
  nickel_nikE: nickel import ATP-binding protein NikE; [R] COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_2258
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor ClpS family protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: OI25_2259
symbol: clpA
gene_biotype: protein_coding
description:
  clpA: ATP-dependent Clp protease ATP-binding subunit ClpA; [O] COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: OI25_226
symbol: OI25_226
gene_biotype: protein_coding
description:
  MBOAT, membrane-bound O-acyltransferase family protein; [M] COG1696 Predicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: OI25_2260
symbol: dut
gene_biotype: protein_coding
description:
  dUTP diphosphatase family protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: OI25_2262
symbol: coaBC
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: OI25_2263
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: OI25_2264
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: OI25_2266
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: OI25_2267
symbol: OI25_2267
gene_biotype: protein_coding
description:
  ubiE/COQ5 methyltransferase family protein; [J] COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: OI25_2268
symbol: OI25_2268
gene_biotype: protein_coding
description:
  Mechanosensitive ion channel family protein; [M] COG3264 Small-conductance mechanosensitive channel.


ensembl_gene_id: OI25_2270
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: OI25_2271
symbol: nadC
gene_biotype: protein_coding
description:
  nadC: nicotinate-nucleotide diphosphorylase; [H] COG0157 Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.


ensembl_gene_id: OI25_2273
symbol: rpmG
gene_biotype: protein_coding
description:
  rpmG_bact: ribosomal protein L33; [J] COG0267 Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: OI25_2274
symbol: rpmB
gene_biotype: protein_coding
description:
  L28: ribosomal protein L28; [J] COG0227 Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: OI25_2275
symbol: OI25_2275
gene_biotype: protein_coding
description:
  Radc: DNA repair RadC family protein; [L] COG2003 DNA repair proteins; Belongs to the UPF0758 family.


ensembl_gene_id: OI25_2277
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: OI25_2284
symbol: argD
gene_biotype: protein_coding
description:
  Aminotransferase class-III family protein; [E] COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: OI25_2285
symbol: OI25_2285
gene_biotype: protein_coding
description:
  2Fe-2S iron-sulfur cluster binding domain protein; [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: OI25_2299
symbol: OI25_2299
gene_biotype: protein_coding
description:
  Serine hydrolase family protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: OI25_2302
symbol: hemN
gene_biotype: protein_coding
description:
  hemN: oxygen-independent coproporphyrinogen III oxidase; [H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: OI25_2305
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: OI25_2306
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: OI25_2311
symbol: OI25_2311
gene_biotype: protein_coding
description:
  NAD binding domain of 6-phosphogluconate dehydrogenase family protein; [S] COG5495 Uncharacterized conserved protein.


ensembl_gene_id: OI25_2316
symbol: ubiD
gene_biotype: protein_coding
description:
  Decarboxylase, UbiD family protein; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: OI25_2319
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: OI25_232
symbol: OI25_232
gene_biotype: protein_coding
description:
  Bacterial cellulose synthase subunit; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: OI25_2320
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: OI25_2321
symbol: ribB-2
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: OI25_2324
symbol: ribD
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: OI25_2325
symbol: hemL
gene_biotype: protein_coding
description:
  hemL: glutamate-1-semialdehyde-2,1-aminomutase; [H] COG0001 Glutamate-1-semialdehyde aminotransferase.


ensembl_gene_id: OI25_2328
symbol: OI25_2328
gene_biotype: protein_coding
description:
  efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_233
symbol: OI25_233
gene_biotype: protein_coding
description:
  wecB: UDP-N-acetylglucosamine 2-epimerase; [M] COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: OI25_2334
symbol: OI25_2334
gene_biotype: protein_coding
description:
  Radical SAM superfamily protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: OI25_2335
symbol: rdgB
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: OI25_2336
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: OI25_2339
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: OI25_2340
symbol: OI25_2340
gene_biotype: protein_coding
description:
  RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: OI25_2344
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: OI25_2345
symbol: OI25_2345
gene_biotype: protein_coding
description:
  Hypothetical protein; OMP85_target: outer membrane insertion C-terminal signal domain protein; [M] COG3203 Outer membrane protein (porin).


ensembl_gene_id: OI25_2348
symbol: OI25_2348
gene_biotype: protein_coding
description:
  Dnaq: exonuclease, DNA polymerase III, epsilon subunit family domain protein; [L] COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases.


ensembl_gene_id: OI25_235
symbol: OI25_235
gene_biotype: protein_coding
description:
  ABC transporter family protein; [P] COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: OI25_2355
symbol: fbp
gene_biotype: protein_coding
description:
  Fructose-1-6-bisphosphatase family protein; [G] COG0158 Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.


ensembl_gene_id: OI25_2356
symbol: higA
gene_biotype: protein_coding
description:
  antidote_HigA: addiction module antidote protein, HigA family; [R] COG3093 Plasmid maintenance system antidote protein.


ensembl_gene_id: OI25_2363
symbol: acpP-2
gene_biotype: protein_coding
description:
  Phosphopantetheine attachment site family protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: OI25_2365
symbol: OI25_2365
gene_biotype: protein_coding
description:
  AMP-binding enzyme family protein; [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.


ensembl_gene_id: OI25_2366
symbol: OI25_2366
gene_biotype: protein_coding
description:
  Bacterial lipid A biosynthesis acyltransferase family protein; [R] COG4261 Predicted acyltransferase.


ensembl_gene_id: OI25_2369
symbol: OI25_2369
gene_biotype: protein_coding
description:
  Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: OI25_237
symbol: OI25_237
gene_biotype: protein_coding
description:
  glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein; [E] COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: OI25_2371
symbol: OI25_2371
gene_biotype: protein_coding
description:
  Thiolase, N-terminal domain protein; [IQ] COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: OI25_2372
symbol: OI25_2372
gene_biotype: protein_coding
description:
  Putative beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA/FabZ; [I] COG4706 Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase.


ensembl_gene_id: OI25_2379
symbol: OI25_2379
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [C] COG0644 Dehydrogenases (flavoproteins).


ensembl_gene_id: OI25_238
symbol: OI25_238
gene_biotype: protein_coding
description:
  NMT1-like family protein; [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: OI25_2380
symbol: guaD
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: OI25_2381
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: OI25_2382
symbol: xdhC
gene_biotype: protein_coding
description:
  xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC; [O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family.


ensembl_gene_id: OI25_2383
symbol: xdhB
gene_biotype: protein_coding
description:
  xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit; [F] COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B.


ensembl_gene_id: OI25_2384
symbol: xdhA
gene_biotype: protein_coding
description:
  xanthine_xdhA: xanthine dehydrogenase, small subunit; [F] COG4630 Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A.


ensembl_gene_id: OI25_2385
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation DsbB family protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: OI25_2390
symbol: OI25_2390
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger family protein; [P] COG0475 Kef-type K+ transport systems, membrane components.


ensembl_gene_id: OI25_2396
symbol: OI25_2396
gene_biotype: protein_coding
description:
  lacY proton/sugar symporter family protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_2397
symbol: OI25_2397
gene_biotype: protein_coding
description:
  lcrH_SycD: type III secretion low calcium response chaperone LcrH/SycD; [R] COG0457 FOG: TPR repeat.


ensembl_gene_id: OI25_2399
symbol: OI25_2399
gene_biotype: protein_coding
description:
  CDF: cation diffusion facilitator transporter family protein; [P] COG1230 Co/Zn/Cd efflux system component.


ensembl_gene_id: OI25_2400
symbol: OI25_2400
gene_biotype: protein_coding
description:
  Thi4 family protein; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: OI25_2402
symbol: OI25_2402
gene_biotype: protein_coding
description:
  Fdh-alpha: formate dehydrogenase, alpha subunit; [R] COG3383 Uncharacterized anaerobic dehydrogenase.


ensembl_gene_id: OI25_2403
symbol: OI25_2403
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase-F iron-sulfur binding region family protein; [C] COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.


ensembl_gene_id: OI25_2404
symbol: OI25_2404
gene_biotype: protein_coding
description:
  Thioredoxin-like [2Fe-2S] ferredoxin family protein; [C] COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.


ensembl_gene_id: OI25_2405
symbol: OI25_2405
gene_biotype: protein_coding
description:
  Bacterial regulatory helix-turn-helix, lysR family protein; [P] COG1910 Periplasmic molybdate-binding protein/domain.


ensembl_gene_id: OI25_2408
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: OI25_241
symbol: OI25_241
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthetase family protein; [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: OI25_2410
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: OI25_2412
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: OI25_2416
symbol: aroA
gene_biotype: protein_coding
description:
  aroA: 3-phosphoshikimate 1-carboxyvinyltransferase; [E] COG0128 5-enolpyruvylshikimate-3-phosphate synthase.


ensembl_gene_id: OI25_2418
symbol: rpsA
gene_biotype: protein_coding
description:
  Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: OI25_2419
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: OI25_2422
symbol: lapB
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat family protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: OI25_2423
symbol: OI25_2423
gene_biotype: protein_coding
description:
  NDP-sugDHase: nucleotide sugar dehydrogenase family protein; [M] COG1004 Predicted UDP-glucose 6-dehydrogenase.


ensembl_gene_id: OI25_2424
symbol: rfaE1
gene_biotype: protein_coding
description:
  rfaE_dom_I: bifunctional protein RfaE, domain I; [M] COG2870 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase.


ensembl_gene_id: OI25_2425
symbol: rfaD
gene_biotype: protein_coding
description:
  ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: OI25_2426
symbol: OI25_2426
gene_biotype: protein_coding
description:
  Helix-hairpin-helix motif family protein; [L] COG1555 DNA uptake protein and related DNA-binding proteins.


ensembl_gene_id: OI25_2427
symbol: cysM
gene_biotype: protein_coding
description:
  cysM: cysteine synthase B; [E] COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: OI25_2432
symbol: metN
gene_biotype: protein_coding
description:
  ABC transporter family protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: OI25_2433
symbol: OI25_2433
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [P] COG2011 ABC-type metal ion transport system, permease component.


ensembl_gene_id: OI25_244
symbol: OI25_244
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein; [CHR] COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: OI25_2443
symbol: rpsP
gene_biotype: protein_coding
description:
  S16: ribosomal protein S16; [J] COG0228 Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: OI25_2444
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: OI25_2445
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine(37)-N(1))-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: OI25_2446
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: OI25_2448
symbol: cobD-2
gene_biotype: protein_coding
description:
  cobD/Cbib family protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: OI25_2450
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: OI25_2452
symbol: orn
gene_biotype: protein_coding
description:
  Exonuclease family protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: OI25_2453
symbol: OI25_2453
gene_biotype: protein_coding
description:
  Molyb_syn: molybdenum cofactor synthesis domain protein; [H] COG0521 Molybdopterin biosynthesis enzymes.


ensembl_gene_id: OI25_2454
symbol: OI25_2454
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [S] COG3028 Uncharacterized protein conserved in bacteria; Belongs to the UPF0307 family.


ensembl_gene_id: OI25_2455
symbol: OI25_2455
gene_biotype: protein_coding
description:
  Modulator of DNA gyrase family protein; [R] COG0312 Predicted Zn-dependent proteases and their inactivated homologs.


ensembl_gene_id: OI25_2456
symbol: OI25_2456
gene_biotype: protein_coding
description:
  Dihydrofolate reductase family protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: OI25_2466
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: OI25_2473
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: OI25_2474
symbol: OI25_2474
gene_biotype: protein_coding
description:
  Phospholipase D family protein; [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: OI25_2480
symbol: OI25_2480
gene_biotype: protein_coding
description:
  Hypothetical protein; uvrD/REP helicase N-terminal domain protein; [L] COG0210 Superfamily I DNA and RNA helicases.


ensembl_gene_id: OI25_2488
symbol: OI25_2488
gene_biotype: protein_coding
description:
  4Fe-4S binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: OI25_2489
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: OI25_2491
symbol: OI25_2491
gene_biotype: protein_coding
description:
  Citrate transporter family protein; [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases.


ensembl_gene_id: OI25_2496
symbol: OI25_2496
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: OI25_2497
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: OI25_2498
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: OI25_2499
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease, Rne/Rng family domain protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: OI25_2500
symbol: OI25_2500
gene_biotype: protein_coding
description:
  Pseudouridine synthase, RluA family protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: OI25_2504
symbol: OI25_2504
gene_biotype: protein_coding
description:
  Tetrapyrrole (Corrin/Porphyrin) Methylases family protein; [R] COG0313 Predicted methyltransferases.


ensembl_gene_id: OI25_2505
symbol: maf
gene_biotype: protein_coding
description:
  Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: OI25_2506
symbol: OI25_2506
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [R] COG1399 Predicted metal-binding, possibly nucleic acid-binding protein.


ensembl_gene_id: OI25_2507
symbol: rpmF
gene_biotype: protein_coding
description:
  rpmF_bact: ribosomal protein L32; [J] COG0333 Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: OI25_2508
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: OI25_2509
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-] synthase III family protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: OI25_251
symbol: nbaD
gene_biotype: protein_coding
description:
  2-amino-3-carboxymuconate 6-semialdehyde decarboxylase; [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: OI25_2510
symbol: fabD
gene_biotype: protein_coding
description:
  fabD: malonyl CoA-acyl carrier protein transacylase; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase.


ensembl_gene_id: OI25_2511
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: OI25_2513
symbol: fabF
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: OI25_2515
symbol: rpoE
gene_biotype: protein_coding
description:
  rpoE_Sigma70: RNA polymerase sigma factor RpoE; [K] COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: OI25_2516
symbol: OI25_2516
gene_biotype: protein_coding
description:
  Hypothetical protein; Anti sigma-E RseA, N-terminal domain protein; [T] COG3073 Negative regulator of sigma E activity.


ensembl_gene_id: OI25_252
symbol: nbaC
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.


ensembl_gene_id: OI25_2520
symbol: lepA
gene_biotype: protein_coding
description:
  Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: OI25_2521
symbol: lepB
gene_biotype: protein_coding
description:
  sigpep_I_bact: signal peptidase I; [U] COG0681 Signal peptidase I; Belongs to the peptidase S26 family.


ensembl_gene_id: OI25_2522
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: OI25_2523
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: OI25_2525
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: OI25_2526
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: OI25_2527
symbol: nagZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: OI25_2529
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: OI25_2531
symbol: OI25_2531
gene_biotype: protein_coding
description:
  Efp_adjacent_2: conserved hypothetical protein, PP_1857 family; [S] COG4394 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_2532
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: OI25_2533
symbol: pgsA
gene_biotype: protein_coding
description:
  pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; [I] COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: OI25_2543
symbol: OI25_2543
gene_biotype: protein_coding
description:
  ahpC/TSA family protein; [R] COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: OI25_2545
symbol: otsA
gene_biotype: protein_coding
description:
  Alpha,alpha-trehalose-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.


ensembl_gene_id: OI25_2546
symbol: OI25_2546
gene_biotype: protein_coding
description:
  ABC transporter family protein; [V] COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: OI25_255
symbol: dmpG
gene_biotype: protein_coding
description:
  4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: OI25_2552
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: OI25_2555
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: OI25_2556
symbol: OI25_2556
gene_biotype: protein_coding
description:
  lysM domain protein; [M] COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: OI25_2558
symbol: carA
gene_biotype: protein_coding
description:
  CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit; [EF] COG0505 Carbamoylphosphate synthase small subunit; Belongs to the CarA family.


ensembl_gene_id: OI25_2559
symbol: carB
gene_biotype: protein_coding
description:
  CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit; [EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family.


ensembl_gene_id: OI25_256
symbol: OI25_256
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: OI25_2560
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA domain protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: OI25_2562
symbol: OI25_2562
gene_biotype: protein_coding
description:
  CRS1 / YhbY domain protein; [J] COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein.


ensembl_gene_id: OI25_2563
symbol: rlmE
gene_biotype: protein_coding
description:
  ftsJ-like methyltransferase family protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: OI25_2564
symbol: hflB
gene_biotype: protein_coding
description:
  ATP-dependent metallopeptidase HflB family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: OI25_2566
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: OI25_2567
symbol: pstS
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, phosphate-binding protein PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: OI25_2568
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: OI25_2569
symbol: pstA
gene_biotype: protein_coding
description:
  3a0107s02c: phosphate ABC transporter, permease protein PstA; [P] COG0581 ABC-type phosphate transport system, permease component.


ensembl_gene_id: OI25_2570
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: OI25_2571
symbol: phoU
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: OI25_2572
symbol: phoB
gene_biotype: protein_coding
description:
  phoB: phosphate regulon transcriptional regulatory protein PhoB; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: OI25_2573
symbol: phoR
gene_biotype: protein_coding
description:
  phoR_proteo: phosphate regulon sensor kinase PhoR; [T] COG0642 Signal transduction histidine kinase.


ensembl_gene_id: OI25_2574
symbol: ppk1
gene_biotype: protein_coding
description:
  Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: OI25_258
symbol: OI25_258
gene_biotype: protein_coding
description:
  OH_muco_semi_DH: 2-hydroxymuconic semialdehyde dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: OI25_2586
symbol: uppP-2
gene_biotype: protein_coding
description:
  Bacitracin resistance BacA family protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: OI25_2599
symbol: alaS
gene_biotype: protein_coding
description:
  alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: OI25_2602
symbol: OI25_2602
gene_biotype: protein_coding
description:
  Beta-eliminating lyase family protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: OI25_2610
symbol: iolB
gene_biotype: protein_coding
description:
  myo_inos_iolB: 5-deoxy-glucuronate isomerase; [G] COG3718 Uncharacterized enzyme involved in inositol metabolism.


ensembl_gene_id: OI25_2612
symbol: iolD
gene_biotype: protein_coding
description:
  myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase; [E] COG3962 Acetolactate synthase; Belongs to the TPP enzyme family.


ensembl_gene_id: OI25_2620
symbol: OI25_2620
gene_biotype: protein_coding
description:
  Sulfurtransferase TusA family protein; [O] COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: OI25_2622
symbol: valS
gene_biotype: protein_coding
description:
  valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: OI25_2624
symbol: mtnN
gene_biotype: protein_coding
description:
  MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: OI25_2625
symbol: prpE
gene_biotype: protein_coding
description:
  propion_prpE: propionate--CoA ligase; [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.


ensembl_gene_id: OI25_2628
symbol: OI25_2628
gene_biotype: protein_coding
description:
  RND_mfp: efflux transporter, RND family, MFP subunit; [V] COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: OI25_2636
symbol: OI25_2636
gene_biotype: protein_coding
description:
  FAD binding domain in molybdopterin dehydrogenase family protein; [C] COG0277 FAD/FMN-containing dehydrogenases.


ensembl_gene_id: OI25_2638
symbol: wrbA
gene_biotype: protein_coding
description:
  NAD(P)H:quinone oxidoreductase, type IV; flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV; [R] COG0655 Multimeric flavodoxin WrbA; Belongs to the WrbA family.


ensembl_gene_id: OI25_2641
symbol: OI25_2641
gene_biotype: protein_coding
description:
  Chlorophyllase enzyme family protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: OI25_2642
symbol: OI25_2642
gene_biotype: protein_coding
description:
  OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase family protein; [E] COG2873 O-acetylhomoserine sulfhydrylase.


ensembl_gene_id: OI25_2645
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: OI25_2647
symbol: OI25_2647
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: OI25_265
symbol: rfbC
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: OI25_2651
symbol: OI25_2651
gene_biotype: protein_coding
description:
  pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit; [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.


ensembl_gene_id: OI25_2652
symbol: OI25_2652
gene_biotype: protein_coding
description:
  pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit; [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit.


ensembl_gene_id: OI25_2657
symbol: thrS
gene_biotype: protein_coding
description:
  threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: OI25_2658
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: OI25_2659
symbol: rpmI
gene_biotype: protein_coding
description:
  rpmI_bact: ribosomal protein L35; [J] COG0291 Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: OI25_2660
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: OI25_2661
symbol: pheS
gene_biotype: protein_coding
description:
  pheS: phenylalanine--tRNA ligase, alpha subunit; [J] COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: OI25_2662
symbol: pheT
gene_biotype: protein_coding
description:
  pheT_bact: phenylalanine--tRNA ligase, beta subunit; [J] COG0072 Phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: OI25_2663
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: OI25_2679
symbol: OI25_2679
gene_biotype: protein_coding
description:
  impE family protein; [R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion.


ensembl_gene_id: OI25_2683
symbol: clpV
gene_biotype: protein_coding
description:
  VI_ClpV1: type VI secretion ATPase, ClpV1 family; [O] COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: OI25_2689
symbol: OI25_2689
gene_biotype: protein_coding
description:
  type_VI_ompA: type VI secretion system peptidoglycan-associated domain; [S] COG3455 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_2690
symbol: icmF
gene_biotype: protein_coding
description:
  Intracellular multiplication and macrophage-killing family protein; [S] COG3523 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_2693
symbol: OI25_2693
gene_biotype: protein_coding
description:
  yidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain protein; [R] COG2985 Predicted permease.


ensembl_gene_id: OI25_2696
symbol: OI25_2696
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase/isomerase family protein; [I] COG1250 3-hydroxyacyl-CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: OI25_2705
symbol: OI25_2705
gene_biotype: protein_coding
description:
  yjgF/chorismate mutase-like, endoribonuclease family protein; [J] COG0251 Putative translation initiation inhibitor, yjgF family.


ensembl_gene_id: OI25_2707
symbol: OI25_2707
gene_biotype: protein_coding
description:
  Beta-eliminating lyase family protein; [E] COG1921 Selenocysteine synthase [seryl-tRNASer selenium transferase].


ensembl_gene_id: OI25_2712
symbol: paaN-2
gene_biotype: protein_coding
description:
  paaN-DH: phenylacetic acid degradation protein paaN; [C] COG1012 NAD-dependent aldehyde dehydrogenases.


ensembl_gene_id: OI25_2714
symbol: aroK-2
gene_biotype: protein_coding
description:
  Helix-turn-helix family protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: OI25_2717
symbol: boxA
gene_biotype: protein_coding
description:
  benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein; [P] COG0369 Sulfite reductase, alpha subunit (flavoprotein).


ensembl_gene_id: OI25_2719
symbol: OI25_2719
gene_biotype: protein_coding
description:
  Hydantase: amidase, hydantoinase/carbamoylase family protein; [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: OI25_2720
symbol: OI25_2720
gene_biotype: protein_coding
description:
  UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain protein; [ER] COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: OI25_2721
symbol: OI25_2721
gene_biotype: protein_coding
description:
  pyrD_sub1_fam: dihydroorotate dehydrogenase family domain protein; [F] COG0167 Dihydroorotate dehydrogenase.


ensembl_gene_id: OI25_2722
symbol: ncs1
gene_biotype: protein_coding
description:
  Ncs1: NCS1 nucleoside transporter family protein; [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases.


ensembl_gene_id: OI25_2727
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: OI25_2737
symbol: OI25_2737
gene_biotype: protein_coding
description:
  Transporter, lactate permease family protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: OI25_2740
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: OI25_2741
symbol: OI25_2741
gene_biotype: protein_coding
description:
  Hypothetical protein; Transcription elongation factor, GreA/GreB, C-term family protein; [K] COG0782 Transcription elongation factor.


ensembl_gene_id: OI25_2743
symbol: OI25_2743
gene_biotype: protein_coding
description:
  Prokaryotic cytochrome b561 family protein; [C] COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein).


ensembl_gene_id: OI25_2744
symbol: OI25_2744
gene_biotype: protein_coding
description:
  Oxidoreductase molybdopterin binding domain protein; [R] COG2041 Sulfite oxidase and related enzymes.


ensembl_gene_id: OI25_2759
symbol: cpdA
gene_biotype: protein_coding
description:
  Calcineurin-like phosphoesterase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: OI25_2760
symbol: OI25_2760
gene_biotype: protein_coding
description:
  ABC transporter family protein; [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_2762
symbol: OI25_2762
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [O] COG0555 ABC-type sulfate transport system, permease component.


ensembl_gene_id: OI25_2775
symbol: OI25_2775
gene_biotype: protein_coding
description:
  pqiA_fam: integral membrane, PqiA family protein; [S] COG2995 Uncharacterized paraquat-inducible protein A.


ensembl_gene_id: OI25_2782
symbol: OI25_2782
gene_biotype: protein_coding
description:
  Hypothetical protein; C-terminal domain of 1-Cys peroxiredoxin family protein; [O] COG0450 Peroxiredoxin.


ensembl_gene_id: OI25_2795
symbol: OI25_2795
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase family protein; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: OI25_2798
symbol: OI25_2798
gene_biotype: protein_coding
description:
  Basic membrane family protein; [R] COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: OI25_2799
symbol: OI25_2799
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region family protein; [FJ] COG0590 Cytosine/adenosine deaminases.


ensembl_gene_id: OI25_2806
symbol: OI25_2806
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: OI25_2813
symbol: OI25_2813
gene_biotype: protein_coding
description:
  Bacterial Fe(2+) trafficking family protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: OI25_2814
symbol: argA
gene_biotype: protein_coding
description:
  N-Ac-Glu-synth: amino-acid N-acetyltransferase; [E] COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: OI25_2820
symbol: OI25_2820
gene_biotype: protein_coding
description:
  Putative molybdopterin binding domain protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA.


ensembl_gene_id: OI25_2824
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen regulation protein NR; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: OI25_2825
symbol: OI25_2825
gene_biotype: protein_coding
description:
  Hypothetical protein; Prolyl oligopeptidase, N-terminal beta-propeller domain protein; [E] COG1505 Serine proteases of the peptidase family S9A.


ensembl_gene_id: OI25_2830
symbol: OI25_2830
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; [FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: OI25_2832
symbol: folD
gene_biotype: protein_coding
description:
  Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: OI25_2837
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: OI25_2838
symbol: aceF
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: OI25_2839
symbol: lpdA
gene_biotype: protein_coding
description:
  lipoamide_DH: dihydrolipoyl dehydrogenase; [C] COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: OI25_2846
symbol: OI25_2846
gene_biotype: protein_coding
description:
  4Fe-4S dicluster domain protein; [C] COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain.


ensembl_gene_id: OI25_285
symbol: nikE-3
gene_biotype: protein_coding
description:
  nickel_nikE: nickel import ATP-binding protein NikE; [R] COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_2850
symbol: OI25_2850
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine phosphatase family protein; [T] COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: OI25_2851
symbol: iscR
gene_biotype: protein_coding
description:
  iscR: iron-sulfur cluster assembly transcription factor IscR; [K] COG1959 Predicted transcriptional regulator.


ensembl_gene_id: OI25_2852
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: OI25_2853
symbol: iscU
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: OI25_2854
symbol: iscA
gene_biotype: protein_coding
description:
  iscA: iron-sulfur cluster assembly protein IscA; [S] COG0316 Uncharacterized conserved protein; Belongs to the HesB/IscA family.


ensembl_gene_id: OI25_2855
symbol: hscB
gene_biotype: protein_coding
description:
  Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: OI25_2856
symbol: hscA
gene_biotype: protein_coding
description:
  Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: OI25_286
symbol: OI25_286
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [R] COG4239 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: OI25_2860
symbol: lysS
gene_biotype: protein_coding
description:
  lysS_bact: lysine--tRNA ligase; [J] COG1190 Lysyl-tRNA synthetase (class II); Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: OI25_2861
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: OI25_2862
symbol: recJ
gene_biotype: protein_coding
description:
  recJ: single-stranded-DNA-specific exonuclease RecJ; [L] COG0608 Single-stranded DNA-specific exonuclease.


ensembl_gene_id: OI25_2865
symbol: OI25_2865
gene_biotype: protein_coding
description:
  lolCE: liporeleasing system, transmembrane, LolC/E family protein; [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component.


ensembl_gene_id: OI25_2866
symbol: lolD
gene_biotype: protein_coding
description:
  Liporeleasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: OI25_2868
symbol: OI25_2868
gene_biotype: protein_coding
description:
  comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2; [R] COG0658 Predicted membrane metal-binding protein.


ensembl_gene_id: OI25_2869
symbol: OI25_2869
gene_biotype: protein_coding
description:
  PGAP1-like family protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: OI25_287
symbol: OI25_287
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [R] COG4174 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: OI25_2870
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: OI25_2871
symbol: kdsA
gene_biotype: protein_coding
description:
  KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase; [M] COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.


ensembl_gene_id: OI25_2872
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: OI25_2873
symbol: ftsB
gene_biotype: protein_coding
description:
  Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: OI25_2875
symbol: OI25_2875
gene_biotype: protein_coding
description:
  Hsp33 family protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: OI25_2876
symbol: OI25_2876
gene_biotype: protein_coding
description:
  Bacterial transferase hexapeptide family protein; [R] COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.


ensembl_gene_id: OI25_288
symbol: OI25_288
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding s, 5 Middle family protein; [E] COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: OI25_2880
symbol: OI25_2880
gene_biotype: protein_coding
description:
  tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family; [J] COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.


ensembl_gene_id: OI25_2882
symbol: trpS-2
gene_biotype: protein_coding
description:
  tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: OI25_2884
symbol: dapA
gene_biotype: protein_coding
description:
  4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: OI25_2887
symbol: OI25_2887
gene_biotype: protein_coding
description:
  Inhibitor of apoptosis-promoting Bax1 family protein; [R] COG0670 Integral membrane protein, interacts with FtsH; Belongs to the BI1 family.


ensembl_gene_id: OI25_2888
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase family protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: OI25_2889
symbol: rlmN
gene_biotype: protein_coding
description:
  23S rRNA (adenine(2503)-C(2))-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: OI25_289
symbol: OI25_289
gene_biotype: protein_coding
description:
  tonB dependent receptor family protein; [P] COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: OI25_2891
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: OI25_2894
symbol: yfgL
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: OI25_2895
symbol: engA
gene_biotype: protein_coding
description:
  Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: OI25_2896
symbol: hfq
gene_biotype: protein_coding
description:
  RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: OI25_2897
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: OI25_29
symbol: OI25_29
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase family protein; [S] COG1359 Uncharacterized conserved protein.


ensembl_gene_id: OI25_2901
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase, regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: OI25_2902
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: OI25_2904
symbol: kup
gene_biotype: protein_coding
description:
  Potassium uptake protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: OI25_2913
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: OI25_2945
symbol: OI25_2945
gene_biotype: protein_coding
description:
  Viral (Super1) RNA helicase family protein; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: OI25_295
symbol: OI25_295
gene_biotype: protein_coding
description:
  Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: OI25_2966
symbol: OI25_2966
gene_biotype: protein_coding
description:
  Inositol monophosphatase family protein; [G] COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: OI25_2967
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH, group 1 family protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: OI25_2969
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine diphosphatase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: OI25_297
symbol: OI25_297
gene_biotype: protein_coding
description:
  Asp_race: aspartate racemase family protein; [M] COG1794 Aspartate racemase; Belongs to the aspartate/glutamate racemases family.


ensembl_gene_id: OI25_2970
symbol: OI25_2970
gene_biotype: protein_coding
description:
  Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD family protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: OI25_2973
symbol: cysS
gene_biotype: protein_coding
description:
  cysS: cysteine--tRNA ligase; [J] COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: OI25_2975
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: OI25_2976
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: OI25_2977
symbol: OI25_2977
gene_biotype: protein_coding
description:
  Asp_kin_monofn: aspartate kinase, monofunctional class; [E] COG0527 Aspartokinases; Belongs to the aspartokinase family.


ensembl_gene_id: OI25_2987
symbol: OI25_2987
gene_biotype: protein_coding
description:
  mobA/MobL family protein; [L] COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: OI25_2988
symbol: OI25_2988
gene_biotype: protein_coding
description:
  N-6 DNA Methylase family protein; [V] COG0286 Type I restriction-modification system methyltransferase subunit.


ensembl_gene_id: OI25_2997
symbol: OI25_2997
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol.


ensembl_gene_id: OI25_3009
symbol: OI25_3009
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [R] COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon.


ensembl_gene_id: OI25_3013
symbol: OI25_3013
gene_biotype: protein_coding
description:
  coA-transferase III family protein; [C] COG1804 Predicted acyl-CoA transferases/carnitine dehydratase.


ensembl_gene_id: OI25_3020
symbol: OI25_3020
gene_biotype: protein_coding
description:
  Tn3 transposase DDE domain protein; [L] COG4644 Transposase and inactivated derivatives, TnpA family.


ensembl_gene_id: OI25_3028
symbol: narAa
gene_biotype: protein_coding
description:
  Naphthalene dioxygenase large subunit; [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: OI25_3035
symbol: OI25_3035
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthetase family protein; [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase.


ensembl_gene_id: OI25_3039
symbol: dapA-2
gene_biotype: protein_coding
description:
  dapA: 4-hydroxy-tetrahydrodipicolinate synthase; [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase.


ensembl_gene_id: OI25_3041
symbol: OI25_3041
gene_biotype: protein_coding
description:
  Ornithine cyclodeaminase/mu-crystallin family protein; [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.


ensembl_gene_id: OI25_3043
symbol: ndoR
gene_biotype: protein_coding
description:
  Naphthalene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component; [HC] COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: OI25_3048
symbol: ndoA
gene_biotype: protein_coding
description:
  Naphthalene 1,2-dioxygenase system ferredoxin subunit; [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: OI25_3050
symbol: OI25_3050
gene_biotype: protein_coding
description:
  AAA domain family protein; [KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain.


ensembl_gene_id: OI25_3053
symbol: phdJ
gene_biotype: protein_coding
description:
  Trans-2'-carboxybenzalpyruvate hydratase-aldolase; [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase.


ensembl_gene_id: OI25_3057
symbol: ndoB
gene_biotype: protein_coding
description:
  Naphthalene 1,2-dioxygenase subunit alpha; [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: OI25_3059
symbol: bphB
gene_biotype: protein_coding
description:
  [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: OI25_3061
symbol: OI25_3061
gene_biotype: protein_coding
description:
  araC-like ligand binding domain protein; [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: OI25_3062
symbol: OI25_3062
gene_biotype: protein_coding
description:
  hpcH/HpaI aldolase/citrate lyase family protein; [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase.


ensembl_gene_id: OI25_3064
symbol: OI25_3064
gene_biotype: protein_coding
description:
  NADPH-dependent FMN reductase family protein; [R] COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: OI25_3074
symbol: OI25_3074
gene_biotype: protein_coding
description:
  Phage_rel_nuc: putative phage-type endonuclease domain protein; [L] COG5377 Phage-related protein, predicted endonuclease.


ensembl_gene_id: OI25_3075
symbol: OI25_3075
gene_biotype: protein_coding
description:
  Phage/plasmid-like TIGR03299 family protein; LGT_TIGR03299: phage/plasmid-like TIGR03299 family protein.


ensembl_gene_id: OI25_3084
symbol: OI25_3084
gene_biotype: protein_coding
description:
  Ribofla_fusion: conserved hypothetical domain protein; [S] COG3236 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_3089
symbol: OI25_3089
gene_biotype: protein_coding
description:
  [G] COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: OI25_3097
symbol: OI25_3097
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: OI25_3099
symbol: gltX
gene_biotype: protein_coding
description:
  glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: OI25_3107
symbol: OI25_3107
gene_biotype: protein_coding
description:
  RraA family protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: OI25_3109
symbol: aceB
gene_biotype: protein_coding
description:
  malate_syn_A: malate synthase A; [C] COG2225 Malate synthase; Belongs to the malate synthase family.


ensembl_gene_id: OI25_3116
symbol: yeaZ
gene_biotype: protein_coding
description:
  T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ; [O] COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: OI25_3120
symbol: thiD
gene_biotype: protein_coding
description:
  HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; [H] COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.


ensembl_gene_id: OI25_3122
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: OI25_3123
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: OI25_3128
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: OI25_3129
symbol: prmB
gene_biotype: protein_coding
description:
  (glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: OI25_3130
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: OI25_3131
symbol: OI25_3131
gene_biotype: protein_coding
description:
  arsC_related: transcriptional regulator, Spx/MgsR family protein; [P] COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: OI25_3132
symbol: dapD
gene_biotype: protein_coding
description:
  dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; [E] COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: OI25_3133
symbol: dapC
gene_biotype: protein_coding
description:
  dapC_gpp: succinyldiaminopimelate transaminase; [E] COG0436 Aspartate/tyrosine/aromatic aminotransferase.


ensembl_gene_id: OI25_3136
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: OI25_3137
symbol: OI25_3137
gene_biotype: protein_coding
description:
  Hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.


ensembl_gene_id: OI25_3138
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: OI25_314
symbol: OI25_314
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase family protein; [R] COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: OI25_3142
symbol: glnD
gene_biotype: protein_coding
description:
  protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: OI25_3143
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: OI25_3144
symbol: rpsB
gene_biotype: protein_coding
description:
  rpsB_bact: ribosomal protein S2; [J] COG0052 Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: OI25_3145
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: OI25_3147
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: OI25_3148
symbol: uppS
gene_biotype: protein_coding
description:
  Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: OI25_3149
symbol: OI25_3149
gene_biotype: protein_coding
description:
  Cytidylyltransferase family protein; [I] COG0575 CDP-diglyceride synthetase; Belongs to the CDS family.


ensembl_gene_id: OI25_3150
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: OI25_3152
symbol: yaeT
gene_biotype: protein_coding
description:
  Outer membrane assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: OI25_3154
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: OI25_3155
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: OI25_3156
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: OI25_3157
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: OI25_3158
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease HII family protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: OI25_3160
symbol: OI25_3160
gene_biotype: protein_coding
description:
  Kinase/pyrophosphorylase family protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: OI25_3161
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: OI25_3163
symbol: OI25_3163
gene_biotype: protein_coding
description:
  SPFH domain / Band 7 family protein; [O] COG0330 Membrane protease subunits, stomatin/prohibitin homologs.


ensembl_gene_id: OI25_3164
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: OI25_3166
symbol: OI25_3166
gene_biotype: protein_coding
description:
  rnfH Ubiquitin family protein; [S] COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family.


ensembl_gene_id: OI25_3168
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: OI25_3172
symbol: OI25_3172
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate phosphomutase family protein; [G] COG2513 PEP phosphonomutase and related enzymes.


ensembl_gene_id: OI25_3173
symbol: OI25_3173
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: OI25_3186
symbol: OI25_3186
gene_biotype: protein_coding
description:
  Decarboxylase, UbiD family protein; [H] COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: OI25_3201
symbol: OI25_3201
gene_biotype: protein_coding
description:
  Organic Anion Transporter Polypeptide family protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_3203
symbol: OI25_3203
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [HC] COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: OI25_322
symbol: OI25_322
gene_biotype: protein_coding
description:
  [E] COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_3223
symbol: OI25_3223
gene_biotype: protein_coding
description:
  LD-carboxypeptidase family protein; [V] COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.


ensembl_gene_id: OI25_3225
symbol: OI25_3225
gene_biotype: protein_coding
description:
  Permease for cytosine/purine, uracil, thiamine, allantoin family protein; [FH] COG1953 Cytosine/uracil/thiamine/allantoin permeases.


ensembl_gene_id: OI25_3232
symbol: uraH
gene_biotype: protein_coding
description:
  Hdxy_isourate: hydroxyisourate hydrolase; [R] COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: OI25_3235
symbol: OI25_3235
gene_biotype: protein_coding
description:
  ABC transporter family protein; [R] COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: OI25_3236
symbol: OI25_3236
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system / permease component family protein; [R] COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_3237
symbol: OI25_3237
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system / permease component family protein; [R] COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_3241
symbol: OI25_3241
gene_biotype: protein_coding
description:
  Miro-like family protein; [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: OI25_3242
symbol: OI25_3242
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase family protein; [R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase.


ensembl_gene_id: OI25_3245
symbol: OI25_3245
gene_biotype: protein_coding
description:
  Phospholipase A1 family protein; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: OI25_3246
symbol: OI25_3246
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding family protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: OI25_3248
symbol: OI25_3248
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [E] COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: OI25_3255
symbol: OI25_3255
gene_biotype: protein_coding
description:
  Flavin-binding monooxygenase-like family protein; [P] COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: OI25_3258
symbol: OI25_3258
gene_biotype: protein_coding
description:
  pspA/IM30 family protein; [KT] COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription.


ensembl_gene_id: OI25_3275
symbol: OI25_3275
gene_biotype: protein_coding
description:
  Conserved hypothetical family protein; [S] COG2855 Predicted membrane protein; Belongs to the UPF0324 family.


ensembl_gene_id: OI25_3288
symbol: OI25_3288
gene_biotype: protein_coding
description:
  Ketopantoate reductase PanE/ApbA family protein; [E] COG1748 Saccharopine dehydrogenase and related proteins.


ensembl_gene_id: OI25_3292
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: OI25_3297
symbol: OI25_3297
gene_biotype: protein_coding
description:
  Hypothetical protein; prkA serine kinase C-terminal domain protein; [T] COG2766 Putative Ser protein kinase.


ensembl_gene_id: OI25_33
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: OI25_3302
symbol: OI25_3302
gene_biotype: protein_coding
description:
  2A0106: MFS transporter, metabolite:H+ symporter family protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_3308
symbol: OI25_3308
gene_biotype: protein_coding
description:
  NMT1/THI5 like family protein; [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: OI25_3309
symbol: OI25_3309
gene_biotype: protein_coding
description:
  Rieske [2Fe-2S] domain protein; [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: OI25_3315
symbol: OI25_3315
gene_biotype: protein_coding
description:
  nodJ: ABC-2 type transporter, NodJ family protein; [V] COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: OI25_3316
symbol: nodI
gene_biotype: protein_coding
description:
  Nodulation ABC transporter NodI; Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4- linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system.


ensembl_gene_id: OI25_3320
symbol: lexA
gene_biotype: protein_coding
description:
  Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: OI25_3322
symbol: cysT
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: OI25_3323
symbol: cysW
gene_biotype: protein_coding
description:
  permease_CysW: sulfate ABC transporter, permease protein CysW; [P] COG4208 ABC-type sulfate transport system, permease component.


ensembl_gene_id: OI25_3324
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATP-binding family protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: OI25_3326
symbol: OI25_3326
gene_biotype: protein_coding
description:
  asnASE_II: L-asparaginase, type II family protein; [EJ] COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; Belongs to the asparaginase 1 family.


ensembl_gene_id: OI25_3328
symbol: OI25_3328
gene_biotype: protein_coding
description:
  Tartro_sem_red: 2-hydroxy-3-oxopropionate reductase; [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: OI25_3329
symbol: hyi
gene_biotype: protein_coding
description:
  OH-pyruv-isom: hydroxypyruvate isomerase; [G] COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.


ensembl_gene_id: OI25_333
symbol: OI25_333
gene_biotype: protein_coding
description:
  Na_symport_lg: putative sodium:solute symporter, VC_2705 subfamily protein; [R] COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: OI25_3330
symbol: gcl
gene_biotype: protein_coding
description:
  Glyox_carbo_lig: glyoxylate carboligase; [R] COG3960 Glyoxylate carboligase; Belongs to the TPP enzyme family.


ensembl_gene_id: OI25_3333
symbol: OI25_3333
gene_biotype: protein_coding
description:
  Zinc-finger family protein; [K] COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor).


ensembl_gene_id: OI25_3335
symbol: priB
gene_biotype: protein_coding
description:
  Putative primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: OI25_3336
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: OI25_3338
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: OI25_3339
symbol: OI25_3339
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [P] COG1392 Phosphate transport regulator (distant homolog of PhoU).


ensembl_gene_id: OI25_334
symbol: OI25_334
gene_biotype: protein_coding
description:
  Na_symport_sm: putative solute:sodium symporter small subunit domain protein; [S] COG4327 Predicted membrane protein.


ensembl_gene_id: OI25_3342
symbol: OI25_3342
gene_biotype: protein_coding
description:
  nlpC/P60 family protein; [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: OI25_3343
symbol: OI25_3343
gene_biotype: protein_coding
description:
  phoH-like family protein; [T] COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: OI25_335
symbol: acs
gene_biotype: protein_coding
description:
  acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: OI25_3350
symbol: OI25_3350
gene_biotype: protein_coding
description:
  Small Multidrug Resistance family protein; [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: OI25_3351
symbol: OI25_3351
gene_biotype: protein_coding
description:
  Dolichyl-phosphate-mannose-mannosyltransferase family protein; [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: OI25_3357
symbol: moaD
gene_biotype: protein_coding
description:
  moaD: molybdopterin converting factor, subunit 1; [H] COG1977 Molybdopterin converting factor, small subunit.


ensembl_gene_id: OI25_3361
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: OI25_3367
symbol: OI25_3367
gene_biotype: protein_coding
description:
  Putative membrane protein; [M] COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: OI25_3369
symbol: OI25_3369
gene_biotype: protein_coding
description:
  Glucose-regulated metallo-peptidase M90 family protein; [S] COG3228 Uncharacterized protein conserved in bacteria; Belongs to the MtfA family.


ensembl_gene_id: OI25_3372
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: OI25_3373
symbol: trxA-2
gene_biotype: protein_coding
description:
  Thioredoxin: thioredoxin; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.


ensembl_gene_id: OI25_3374
symbol: dnaX
gene_biotype: protein_coding
description:
  dnaX_nterm: DNA polymerase III, subunit gamma and tau; [L] COG2812 DNA polymerase III, gamma/tau subunits.


ensembl_gene_id: OI25_3375
symbol: OI25_3375
gene_biotype: protein_coding
description:
  DNA-binding protein, YbaB/EbfC family; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: OI25_3376
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: OI25_3378
symbol: OI25_3378
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding s, 3 family protein; [P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: OI25_3381
symbol: OI25_3381
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase family protein; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: OI25_3382
symbol: surE
gene_biotype: protein_coding
description:
  5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: OI25_3383
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: OI25_3385
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: OI25_3387
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: OI25_3388
symbol: yfiO
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoYfiO family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: OI25_3389
symbol: OI25_3389
gene_biotype: protein_coding
description:
  rluA_subfam: pseudouridine synthase, RluA family protein; [J] COG0564 Pseudouridylate synthases, 23S RNA-specific; Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: OI25_3390
symbol: OI25_3390
gene_biotype: protein_coding
description:
  Multi-copper polyphenol oxidoreductase laccase family protein; [S] COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: OI25_3393
symbol: phbB-1
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: OI25_3394
symbol: phaR
gene_biotype: protein_coding
description:
  PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR; [S] COG5394 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_34
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: OI25_3403
symbol: OI25_3403
gene_biotype: protein_coding
description:
  [H] COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase).


ensembl_gene_id: OI25_3418
symbol: dusC
gene_biotype: protein_coding
description:
  Dihydrouridine synthase family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: OI25_3419
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: OI25_3423
symbol: metC
gene_biotype: protein_coding
description:
  cysta_beta_ly_B: cystathionine beta-lyase; [E] COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.


ensembl_gene_id: OI25_3428
symbol: ku
gene_biotype: protein_coding
description:
  Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: OI25_343
symbol: OI25_343
gene_biotype: protein_coding
description:
  fliQ_rel_III: type III secretion, HrpO family protein; [U] COG4794 Type III secretory pathway, component EscS.


ensembl_gene_id: OI25_3432
symbol: OI25_3432
gene_biotype: protein_coding
description:
  Adh_fam_1: zinc-binding alcohol dehydrogenase family protein; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: OI25_3434
symbol: OI25_3434
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [R] COG0390 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: OI25_3435
symbol: OI25_3435
gene_biotype: protein_coding
description:
  ABC transporter family protein; [R] COG4619 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: OI25_3438
symbol: OI25_3438
gene_biotype: protein_coding
description:
  HAMP domain protein; [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase).


ensembl_gene_id: OI25_344
symbol: epaP
gene_biotype: protein_coding
description:
  yscR: type III secretion apparatus protein, YscR/HrcR family; [U] COG4790 Type III secretory pathway, component EscR.


ensembl_gene_id: OI25_3441
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: OI25_3443
symbol: argE
gene_biotype: protein_coding
description:
  acOrn-deacetyl: acetylornithine deacetylase; [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: OI25_3444
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: OI25_3445
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: OI25_3446
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: OI25_3459
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: OI25_346
symbol: OI25_346
gene_biotype: protein_coding
description:
  Nodulation NolV family protein; [NU] COG1317 Flagellar biosynthesis/type III secretory pathway protein.


ensembl_gene_id: OI25_3461
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: OI25_3462
symbol: lon
gene_biotype: protein_coding
description:
  Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: OI25_3467
symbol: OI25_3467
gene_biotype: protein_coding
description:
  Hypothetical protein; tonB_Cterm: TonB family C-terminal domain protein; [M] COG0810 Periplasmic protein TonB, links inner and outer membranes.


ensembl_gene_id: OI25_3470
symbol: OI25_3470
gene_biotype: protein_coding
description:
  PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family protein; [G] COG4993 Glucose dehydrogenase.


ensembl_gene_id: OI25_3474
symbol: pqqC
gene_biotype: protein_coding
description:
  PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C; [H] COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C.


ensembl_gene_id: OI25_3475
symbol: pqqB
gene_biotype: protein_coding
description:
  PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B; [R] COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.


ensembl_gene_id: OI25_3476
symbol: OI25_3476
gene_biotype: protein_coding
description:
  Bacterial regulatory, Fis family protein; [QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism.


ensembl_gene_id: OI25_348
symbol: OI25_348
gene_biotype: protein_coding
description:
  III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family; [U] COG4669 Type III secretory pathway, lipoprotein EscJ.


ensembl_gene_id: OI25_3482
symbol: OI25_3482
gene_biotype: protein_coding
description:
  Adh_fam_2: zinc-binding alcohol dehydrogenase family protein; [R] COG1064 Zn-dependent alcohol dehydrogenases.


ensembl_gene_id: OI25_3483
symbol: OI25_3483
gene_biotype: protein_coding
description:
  Bacterial regulatory s, crp family protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: OI25_3489
symbol: OI25_3489
gene_biotype: protein_coding
description:
  Natural resistance-associated macrophage family protein; [P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family.


ensembl_gene_id: OI25_3495
symbol: acs-2
gene_biotype: protein_coding
description:
  ac_CoA_lig_AcsA: acetate--CoA ligase; [I] COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.


ensembl_gene_id: OI25_3496
symbol: OI25_3496
gene_biotype: protein_coding
description:
  RNA-metabolising metallo-beta-lactamase family protein; [J] COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: OI25_35
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: OI25_3500
symbol: phbB
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase domain protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: OI25_3512
symbol: OI25_3512
gene_biotype: protein_coding
description:
  ABC transporter family protein; [Q] COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: OI25_3513
symbol: pgi
gene_biotype: protein_coding
description:
  Phosphoglucose isomerase family protein; [G] COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.


ensembl_gene_id: OI25_3514
symbol: nnrE
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow  [...]


ensembl_gene_id: OI25_3516
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: OI25_3518
symbol: OI25_3518
gene_biotype: protein_coding
description:
  Hypothetical protein; couple_hipA: HipA N-terminal domain protein; [R] COG3550 Uncharacterized protein related to capsule biosynthesis enzymes.


ensembl_gene_id: OI25_3520
symbol: OI25_3520
gene_biotype: protein_coding
description:
  bolA-like family protein; [T] COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.


ensembl_gene_id: OI25_3521
symbol: ispZ
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: OI25_3522
symbol: msrB
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase; [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: OI25_3523
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: OI25_3534
symbol: OI25_3534
gene_biotype: protein_coding
description:
  Aminomethyltransferase folate-binding domain protein; [R] COG0354 Predicted aminomethyltransferase related to GcvT.


ensembl_gene_id: OI25_3535
symbol: mltG
gene_biotype: protein_coding
description:
  yceG-like family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: OI25_3536
symbol: tmk
gene_biotype: protein_coding
description:
  dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: OI25_354
symbol: OI25_354
gene_biotype: protein_coding
description:
  type_III_yscC: type III secretion outer membrane pore, YscC/HrcC family; [NU] COG1450 Type II secretory pathway, component PulD.


ensembl_gene_id: OI25_3550
symbol: OI25_3550
gene_biotype: protein_coding
description:
  GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; [M] COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: OI25_3551
symbol: OI25_3551
gene_biotype: protein_coding
description:
  wcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase; [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis.


ensembl_gene_id: OI25_3555
symbol: OI25_3555
gene_biotype: protein_coding
description:
  Eps_fam: capsular exopolysaccharide family domain protein; [M] COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.


ensembl_gene_id: OI25_3556
symbol: OI25_3556
gene_biotype: protein_coding
description:
  Glycosyl transferase 21 family protein; [M] COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: OI25_356
symbol: OI25_356
gene_biotype: protein_coding
description:
  Ribbon-helix-helix domain protein; [R] COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis.


ensembl_gene_id: OI25_3563
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: OI25_3567
symbol: OI25_3567
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis family protein; [R] COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: OI25_3576
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: OI25_3584
symbol: OI25_3584
gene_biotype: protein_coding
description:
  His Kinase A domain protein; [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase).


ensembl_gene_id: OI25_3585
symbol: nirB
gene_biotype: protein_coding
description:
  nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit; [C] COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: OI25_3586
symbol: nirD
gene_biotype: protein_coding
description:
  nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit; [PR] COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: OI25_3587
symbol: OI25_3587
gene_biotype: protein_coding
description:
  FAD binding domain protein; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: OI25_359
symbol: OI25_359
gene_biotype: protein_coding
description:
  Hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: OI25_3608
symbol: OI25_3608
gene_biotype: protein_coding
description:
  Aminotransferase class-III family protein; [H] COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: OI25_3615
symbol: fabV
gene_biotype: protein_coding
description:
  NAD(P)H binding domain of trans-2-enoyl-CoA reductase family protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: OI25_3629
symbol: OI25_3629
gene_biotype: protein_coding
description:
  Organ_hyd_perox: peroxiredoxin, Ohr subfamily protein; [O] COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: OI25_3633
symbol: OI25_3633
gene_biotype: protein_coding
description:
  [I] COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: OI25_3648
symbol: atzF
gene_biotype: protein_coding
description:
  Allophanate_hyd: allophanate hydrolase; [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: OI25_3655
symbol: OI25_3655
gene_biotype: protein_coding
description:
  Dienelactone hydrolase family protein; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: OI25_3660
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: OI25_3665
symbol: OI25_3665
gene_biotype: protein_coding
description:
  Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein; [T] COG0642 Signal transduction histidine kinase.


ensembl_gene_id: OI25_3668
symbol: OI25_3668
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [R] COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding.


ensembl_gene_id: OI25_3675
symbol: OI25_3675
gene_biotype: protein_coding
description:
  NAD binding domain of 6-phosphogluconate dehydrogenase family protein; [R] COG2085 Predicted dinucleotide-binding enzymes.


ensembl_gene_id: OI25_3682
symbol: OI25_3682
gene_biotype: protein_coding
description:
  2Fe-2S iron-sulfur cluster binding domain protein; [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: OI25_3683
symbol: OI25_3683
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: OI25_3686
symbol: OI25_3686
gene_biotype: protein_coding
description:
  2OG-Fe(II) oxygenase superfamily protein; [R] COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: OI25_3688
symbol: phnW
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.


ensembl_gene_id: OI25_3699
symbol: catA
gene_biotype: protein_coding
description:
  Catalase; Catechol 1,2-dioxygenase; catechol_proteo: catechol 1,2-dioxygenase; [Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit.


ensembl_gene_id: OI25_3700
symbol: OI25_3700
gene_biotype: protein_coding
description:
  Mucon_cyclo: muconate and chloromuconate cycloisomerases family protein; [MR] COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: OI25_3713
symbol: hpaC
gene_biotype: protein_coding
description:
  hpaC: 4-hydroxyphenylacetate 3-monooxygenase, reductase component; [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: OI25_3718
symbol: OI25_3718
gene_biotype: protein_coding
description:
  NMT1-like family protein; [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: OI25_3724
symbol: OI25_3724
gene_biotype: protein_coding
description:
  acrB/AcrD/AcrF family protein; [P] COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: OI25_3740
symbol: kdgT
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate transporter; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family.


ensembl_gene_id: OI25_3741
symbol: kduI
gene_biotype: protein_coding
description:
  kduI/IolB family protein; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.


ensembl_gene_id: OI25_3742
symbol: kduD
gene_biotype: protein_coding
description:
  kduD: 2-deoxy-D-gluconate 3-dehydrogenase; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: OI25_375
symbol: OI25_375
gene_biotype: protein_coding
description:
  Fe2+ transport family protein; [P] COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport.


ensembl_gene_id: OI25_3756
symbol: OI25_3756
gene_biotype: protein_coding
description:
  Glycosyl transferase 2 family protein; [M] COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: OI25_376
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: OI25_377
symbol: OI25_377
gene_biotype: protein_coding
description:
  Aminotransferase class I and II family protein; [E] COG1448 Aspartate/tyrosine/aromatic aminotransferase.


ensembl_gene_id: OI25_3772
symbol: OI25_3772
gene_biotype: protein_coding
description:
  Peptidase M20/M25/M40 family protein; [E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: OI25_3780
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA dihydrouridine synthase A family protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: OI25_3788
symbol: ssuB
gene_biotype: protein_coding
description:
  ABC transporter family protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: OI25_379
symbol: OI25_379
gene_biotype: protein_coding
description:
  PHB_DH: 3-hydroxybutyrate dehydrogenase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: OI25_3790
symbol: ssuD
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase, FMNH(2)-dependent; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: OI25_3798
symbol: OI25_3798
gene_biotype: protein_coding
description:
  Small Multidrug Resistance family protein; [P] COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: OI25_3801
symbol: OI25_3801
gene_biotype: protein_coding
description:
  NUDIX domain protein; [F] COG1051 ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family.


ensembl_gene_id: OI25_3802
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: OI25_3803
symbol: bpt
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: OI25_3804
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: OI25_3808
symbol: OI25_3808
gene_biotype: protein_coding
description:
  Oxidoreductase, NAD-binding Rossmann fold family protein; [R] COG0673 Predicted dehydrogenases and related proteins.


ensembl_gene_id: OI25_381
symbol: rlmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase D, RsmJ family protein; Specifically methylates the adenine in position 2030 of 23S rRNA.


ensembl_gene_id: OI25_3810
symbol: pheA2
gene_biotype: protein_coding
description:
  Phenol 2-hydroxylase component B domain protein; [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: OI25_3817
symbol: OI25_3817
gene_biotype: protein_coding
description:
  Crp-like helix-turn-helix domain protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: OI25_3820
symbol: OI25_3820
gene_biotype: protein_coding
description:
  Putative hTH-type transcriptional regulator,YgjM-like protein; [K] COG5499 Predicted transcription regulator containing HTH domain.


ensembl_gene_id: OI25_3822
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: OI25_3823
symbol: rlmB
gene_biotype: protein_coding
description:
  RNA 2'-O ribose methyltransferase substrate binding family protein; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: OI25_3824
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: OI25_3851
symbol: OI25_3851
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; [R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: OI25_3859
symbol: OI25_3859
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase family protein; [Q] COG1233 Phytoene dehydrogenase and related proteins.


ensembl_gene_id: OI25_386
symbol: mAT2B
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase 2 subunit beta; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: OI25_3860
symbol: OI25_3860
gene_biotype: protein_coding
description:
  [R] COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: OI25_3869
symbol: OI25_3869
gene_biotype: protein_coding
description:
  UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain protein; [I] COG1250 3-hydroxyacyl-CoA dehydrogenase.


ensembl_gene_id: OI25_387
symbol: dnaE
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: OI25_3874
symbol: OI25_3874
gene_biotype: protein_coding
description:
  3-beta hydroxysteroid dehydrogenase/isomerase family protein; [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: OI25_3878
symbol: OI25_3878
gene_biotype: protein_coding
description:
  UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain protein; [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: OI25_388
symbol: OI25_388
gene_biotype: protein_coding
description:
  impB/mucB/samB family protein; [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair.


ensembl_gene_id: OI25_3884
symbol: OI25_3884
gene_biotype: protein_coding
description:
  Hypothetical protein; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain protein; [R] COG4032 Predicted thiamine-pyrophosphate-binding protein.


ensembl_gene_id: OI25_3885
symbol: OI25_3885
gene_biotype: protein_coding
description:
  Hypothetical protein; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain protein; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: OI25_3914
symbol: OI25_3914
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: OI25_3922
symbol: ehuD
gene_biotype: protein_coding
description:
  ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD; [E] COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: OI25_3923
symbol: ehuC
gene_biotype: protein_coding
description:
  ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC; [E] COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: OI25_3924
symbol: ehuB
gene_biotype: protein_coding
description:
  ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB; [ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: OI25_3925
symbol: ehuA
gene_biotype: protein_coding
description:
  ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA; [E] COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: OI25_3928
symbol: OI25_3928
gene_biotype: protein_coding
description:
  Aminotransferase class-III family protein; [H] COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: OI25_3932
symbol: eutC
gene_biotype: protein_coding
description:
  ectoine_eutC: ectoine utilization protein EutC; [E] COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.


ensembl_gene_id: OI25_3942
symbol: OI25_3942
gene_biotype: protein_coding
description:
  Taurine catabolism dioxygenase TauD, TfdA family protein; [Q] COG2175 Probable taurine catabolism dioxygenase.


ensembl_gene_id: OI25_3944
symbol: OI25_3944
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.


ensembl_gene_id: OI25_3947
symbol: xylG
gene_biotype: protein_coding
description:
  D-xylose ABC transporter, ATP-binding protein; [G] COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: OI25_3960
symbol: pchF
gene_biotype: protein_coding
description:
  4-cresol dehydrogenase [hydroxylating] flavoprotein subunit; [C] COG0277 FAD/FMN-containing dehydrogenases.


ensembl_gene_id: OI25_397
symbol: OI25_397
gene_biotype: protein_coding
description:
  Sigma-70, region 4 family protein; [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: OI25_3977
symbol: OI25_3977
gene_biotype: protein_coding
description:
  Bacterial type II and III secretion system family protein; [U] COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: OI25_398
symbol: OI25_398
gene_biotype: protein_coding
description:
  Cobalt uptake substrate-specific transmembrane region family protein; [S] COG3235 Predicted membrane protein.


ensembl_gene_id: OI25_3990
symbol: OI25_3990
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase family protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: OI25_3991
symbol: OI25_3991
gene_biotype: protein_coding
description:
  Heavy-metal-binding family protein; [S] COG0393 Uncharacterized conserved protein; Belongs to the UPF0145 family.


ensembl_gene_id: OI25_3996
symbol: OI25_3996
gene_biotype: protein_coding
description:
  Cupin family protein; [S] COG4297 Uncharacterized protein containing double-stranded beta helix domain.


ensembl_gene_id: OI25_40
symbol: OI25_40
gene_biotype: protein_coding
description:
  Mechanosensitive ion channel family protein; [M] COG0668 Small-conductance mechanosensitive channel.


ensembl_gene_id: OI25_4001
symbol: choX
gene_biotype: protein_coding
description:
  ABC_choline_bnd: choline ABC transporter, periplasmic binding family protein; [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: OI25_4007
symbol: OI25_4007
gene_biotype: protein_coding
description:
  Substrate binding domain of ABC-type glycine betaine transport system family protein; [E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: OI25_401
symbol: OI25_401
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [S] COG3022 Uncharacterized protein conserved in bacteria; Belongs to the UPF0246 family.


ensembl_gene_id: OI25_4015
symbol: OI25_4015
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [E] COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog.


ensembl_gene_id: OI25_4016
symbol: glyA2
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: OI25_4018
symbol: fdhA
gene_biotype: protein_coding
description:
  fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent; [ER] COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: OI25_4020
symbol: betB
gene_biotype: protein_coding
description:
  Betaine-aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: OI25_4021
symbol: betA
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: OI25_4025
symbol: OI25_4025
gene_biotype: protein_coding
description:
  soxA: sarcosine oxidase, alpha subunit; [E] COG0404 Glycine cleavage system T protein (aminomethyltransferase); Belongs to the GcvT family.


ensembl_gene_id: OI25_4032
symbol: choW
gene_biotype: protein_coding
description:
  ABC_choXWV_perm: choline ABC transporter, permease protein; [E] COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: OI25_4033
symbol: proV
gene_biotype: protein_coding
description:
  proV: glycine betaine/L-proline transport ATP binding subunit; [E] COG4175 ABC-type proline/glycine betaine transport system, ATPase component.


ensembl_gene_id: OI25_405
symbol: OI25_405
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein; [I] COG1250 3-hydroxyacyl-CoA dehydrogenase.


ensembl_gene_id: OI25_4054
symbol: OI25_4054
gene_biotype: protein_coding
description:
  FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family protein; [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: OI25_4056
symbol: rutF
gene_biotype: protein_coding
description:
  NAD(P)H-flavin reductase RutF; [R] COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: OI25_4068
symbol: cyoD
gene_biotype: protein_coding
description:
  cyoD: cytochrome o ubiquinol oxidase subunit IV; [C] COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4.


ensembl_gene_id: OI25_4069
symbol: cyoC
gene_biotype: protein_coding
description:
  cyoC: cytochrome o ubiquinol oxidase, subunit III; [C] COG1845 Heme/copper-type cytochrome/quinol oxidase, subunit 3.


ensembl_gene_id: OI25_4070
symbol: cyoB
gene_biotype: protein_coding
description:
  cyoB: cytochrome o ubiquinol oxidase, subunit I; [C] COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: OI25_4071
symbol: cyoA
gene_biotype: protein_coding
description:
  cyoA: ubiquinol oxidase, subunit II; [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2.


ensembl_gene_id: OI25_4072
symbol: OI25_4072
gene_biotype: protein_coding
description:
  NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M family protein; [C] COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M).


ensembl_gene_id: OI25_4073
symbol: OI25_4073
gene_biotype: protein_coding
description:
  ABC transporter family protein; [V] COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: OI25_4074
symbol: OI25_4074
gene_biotype: protein_coding
description:
  ftsX-like permease family protein; [V] COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: OI25_4084
symbol: cobN
gene_biotype: protein_coding
description:
  cobalto_cobN: cobaltochelatase, CobN subunit; [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: OI25_4087
symbol: cobO
gene_biotype: protein_coding
description:
  cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: OI25_4088
symbol: cbiA
gene_biotype: protein_coding
description:
  cobB/CobQ-like glutamine amidotransferase domain protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: OI25_4095
symbol: OI25_4095
gene_biotype: protein_coding
description:
  Winged helix DNA-binding domain protein; [KG] COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: OI25_4099
symbol: OI25_4099
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase family protein; [E] COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.


ensembl_gene_id: OI25_4100
symbol: OI25_4100
gene_biotype: protein_coding
description:
  Catalase family protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.


ensembl_gene_id: OI25_4105
symbol: lifO
gene_biotype: protein_coding
description:
  Lipase chaperone; May be involved in the folding of the extracellular lipase during its passage through the periplasm; Belongs to the lipase chaperone family.


ensembl_gene_id: OI25_4110
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: OI25_4113
symbol: OI25_4113
gene_biotype: protein_coding
description:
  3mg: DNA-3-methyladenine glycosylase family protein; [L] COG2094 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family.


ensembl_gene_id: OI25_4117
symbol: OI25_4117
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding family protein; [E] COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: OI25_4135
symbol: OI25_4135
gene_biotype: protein_coding
description:
  Nudix-type nucleoside diphosphatase, YffH/AdpP family protein; [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: OI25_4142
symbol: OI25_4142
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: OI25_4162
symbol: narJ
gene_biotype: protein_coding
description:
  narJ: nitrate reductase molybdenum cofactor assembly chaperone; [C] COG2180 Nitrate reductase delta subunit.


ensembl_gene_id: OI25_4164
symbol: OI25_4164
gene_biotype: protein_coding
description:
  narG: nitrate reductase, alpha subunit; [C] COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: OI25_4179
symbol: OI25_4179
gene_biotype: protein_coding
description:
  VI_effect_Hcp1: type VI secretion system effector, Hcp1 family protein; [S] COG3157 Hemolysin-coregulated protein (uncharacterized).


ensembl_gene_id: OI25_4185
symbol: OI25_4185
gene_biotype: protein_coding
description:
  IV_VI_DotU: type IV/VI secretion system, DotU family domain protein; [S] COG3455 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_4188
symbol: urtE
gene_biotype: protein_coding
description:
  urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE; [E] COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: OI25_4189
symbol: urtD
gene_biotype: protein_coding
description:
  urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD; [R] COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: OI25_4190
symbol: urtC
gene_biotype: protein_coding
description:
  urea_trans_UrtC: urea ABC transporter, permease protein UrtC; [E] COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_4191
symbol: urtB
gene_biotype: protein_coding
description:
  urea_trans_UrtB: urea ABC transporter, permease protein UrtB; [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_4194
symbol: OI25_4194
gene_biotype: protein_coding
description:
  Bacterial regulatory s, luxR family protein; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: OI25_4195
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: OI25_420
symbol: nuoN
gene_biotype: protein_coding
description:
  Proton-translocating NADH-quinone oxidoreductase, chain N family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: OI25_4205
symbol: OI25_4205
gene_biotype: protein_coding
description:
  Oxidoreductase molybdopterin binding domain protein; [S] COG3915 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_4215
symbol: OI25_4215
gene_biotype: protein_coding
description:
  TRAP_TAXI: TRAP transporter solute receptor, TAXI family protein; [R] COG2358 TRAP-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: OI25_422
symbol: OI25_422
gene_biotype: protein_coding
description:
  NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L family protein; [CP] COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: OI25_4224
symbol: OI25_4224
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase family protein; [P] COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: OI25_423
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 4L family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: OI25_424
symbol: OI25_424
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 6 family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: OI25_4241
symbol: OI25_4241
gene_biotype: protein_coding
description:
  dctM: TRAP transporter, DctM subunit; [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: OI25_4242
symbol: OI25_4242
gene_biotype: protein_coding
description:
  Tripartite ATP-independent periplasmic transporter, DctQ component family protein; [G] COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.


ensembl_gene_id: OI25_4243
symbol: OI25_4243
gene_biotype: protein_coding
description:
  dctP: TRAP transporter solute receptor, DctP family protein; [G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: OI25_4247
symbol: kdgD
gene_biotype: protein_coding
description:
  kdgD: 5-dehydro-4-deoxyglucarate dehydratase; [EM] COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: OI25_4248
symbol: OI25_4248
gene_biotype: protein_coding
description:
  2A0114: D-galactonate transporter family protein; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_425
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, chain I family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: OI25_4251
symbol: garL
gene_biotype: protein_coding
description:
  garL: 2-dehydro-3-deoxyglucarate aldolase; [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: OI25_426
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: OI25_4268
symbol: OI25_4268
gene_biotype: protein_coding
description:
  Bacterial extracellular solute-binding family protein; [P] COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: OI25_427
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone), G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: OI25_428
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH oxidoreductase (quinone), F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: OI25_4284
symbol: OI25_4284
gene_biotype: protein_coding
description:
  N-acetyltransferase family protein; [Q] COG2162 Arylamine N-acetyltransferase; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: OI25_4289
symbol: OI25_4289
gene_biotype: protein_coding
description:
  Binding--dependent transport system inner membrane component family protein; [P] COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: OI25_429
symbol: nuoE
gene_biotype: protein_coding
description:
  nuoE_fam: NADH-quinone oxidoreductase, E subunit; [C] COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit.


ensembl_gene_id: OI25_4297
symbol: mdcB
gene_biotype: protein_coding
description:
  triphosphoribosyl-dephospho-CoA synthase MdcB; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family.


ensembl_gene_id: OI25_4299
symbol: mdcD
gene_biotype: protein_coding
description:
  Malonate_beta: biotin-independent malonate decarboxylase, beta subunit; [I] COG0777 Acetyl-CoA carboxylase beta subunit.


ensembl_gene_id: OI25_430
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone), D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: OI25_4302
symbol: mdcH
gene_biotype: protein_coding
description:
  malonate_mdcH: malonate decarboxylase, epsilon subunit; [I] COG0331 (acyl-carrier-protein) S-malonyltransferase.


ensembl_gene_id: OI25_431
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: OI25_432
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: OI25_4327
symbol: phnY
gene_biotype: protein_coding
description:
  phnAcAld_DH: putative phosphonoacetaldehyde dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: OI25_4329
symbol: OI25_4329
gene_biotype: protein_coding
description:
  phnR_burk: phosphonate utilization associated transcriptional regulator; [K] COG1802 Transcriptional regulators.


ensembl_gene_id: OI25_433
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: OI25_4330
symbol: phnV
gene_biotype: protein_coding
description:
  phnV: 2-aminoethylphosphonate ABC transport system, membrane component PhnV; [E] COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: OI25_4331
symbol: phnU
gene_biotype: protein_coding
description:
  phnU: 2-aminoethylphosphonate ABC transporter, permease protein; [O] COG0555 ABC-type sulfate transport system, permease component.


ensembl_gene_id: OI25_4332
symbol: phnT
gene_biotype: protein_coding
description:
  phnT: 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_4333
symbol: phnS
gene_biotype: protein_coding
description:
  phnS: 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein; [P] COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: OI25_4339
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: OI25_435
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: OI25_4351
symbol: OI25_4351
gene_biotype: protein_coding
description:
  osmC-like family protein; [O] COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: OI25_436
symbol: tpiA
gene_biotype: protein_coding
description:
  Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: OI25_437
symbol: OI25_437
gene_biotype: protein_coding
description:
  Quinone_pig3: NAD(P)H quinone oxidoreductase, PIG3 family protein; [CR] COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: OI25_4373
symbol: OI25_4373
gene_biotype: protein_coding
description:
  Ketopantoate reductase PanE/ApbA family protein; [I] COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: OI25_438
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: OI25_4383
symbol: xsc
gene_biotype: protein_coding
description:
  Sulphoacet_xsc: sulfoacetaldehyde acetyltransferase; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: OI25_439
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: OI25_4394
symbol: OI25_4394
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; [R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.


ensembl_gene_id: OI25_4395
symbol: OI25_4395
gene_biotype: protein_coding
description:
  Sodium:solute symporter family protein; [ER] COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: OI25_44
symbol: OI25_44
gene_biotype: protein_coding
description:
  pfpI: intracellular protease, PfpI family protein; [R] COG0693 Putative intracellular protease/amidase.


ensembl_gene_id: OI25_4406
symbol: dctA
gene_biotype: protein_coding
description:
  Aerobic C4-dicarboxylate transport protein; [C] COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: OI25_4407
symbol: OI25_4407
gene_biotype: protein_coding
description:
  Hypothetical protein; D-galactarate dehydratase / Altronate hydrolase, C terminus family protein; [G] COG2721 Altronate dehydratase.


ensembl_gene_id: OI25_4411
symbol: OI25_4411
gene_biotype: protein_coding
description:
  HAD-SF-IA-v2: HAD hydrolase, IA, variant 2 family protein; [R] COG1011 Predicted hydrolase (HAD superfamily).


ensembl_gene_id: OI25_4415
symbol: OI25_4415
gene_biotype: protein_coding
description:
  Type I phosphodiesterase / nucleotide pyrophosphatase family protein; [P] COG3119 Arylsulfatase A and related enzymes.


ensembl_gene_id: OI25_442
symbol: OI25_442
gene_biotype: protein_coding
description:
  Carbonic anhydrase family protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: OI25_4429
symbol: hpaR
gene_biotype: protein_coding
description:
  hpaR: homoprotocatechuate degradation operon regulator, HpaR; [K] COG1846 Transcriptional regulators.


ensembl_gene_id: OI25_4431
symbol: hpaG
gene_biotype: protein_coding
description:
  hpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: OI25_4432
symbol: hpaE
gene_biotype: protein_coding
description:
  hpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: OI25_4436
symbol: hpaI
gene_biotype: protein_coding
description:
  hpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; [G] COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: OI25_444
symbol: leuA-2
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: OI25_4442
symbol: yhjQ
gene_biotype: protein_coding
description:
  cellulose_yhjQ: cellulose synthase operon protein YhjQ; [D] COG1192 ATPases involved in chromosome partitioning.


ensembl_gene_id: OI25_4443
symbol: bcsA
gene_biotype: protein_coding
description:
  celA: cellulose synthase catalytic subunit; [M] COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.


ensembl_gene_id: OI25_445
symbol: pssA
gene_biotype: protein_coding
description:
  pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase; [I] COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: OI25_446
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase family protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: OI25_4465
symbol: OI25_4465
gene_biotype: protein_coding
description:
  yceI-like domain protein; [S] COG2353 Uncharacterized conserved protein; Belongs to the UPF0312 family.


ensembl_gene_id: OI25_447
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: OI25_4472
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: OI25_4473
symbol: OI25_4473
gene_biotype: protein_coding
description:
  acyl-CoA reductase family protein; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: OI25_4474
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: OI25_4478
symbol: dinB
gene_biotype: protein_coding
description:
  Hypothetical protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: OI25_448
symbol: ilvN
gene_biotype: protein_coding
description:
  Acolac_sm: acetolactate synthase, small subunit; [E] COG0440 Acetolactate synthase, small (regulatory) subunit.


ensembl_gene_id: OI25_449
symbol: ilvB
gene_biotype: protein_coding
description:
  Acolac_lg: acetolactate synthase, large subunit, biosynthetic type; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: OI25_4494
symbol: OI25_4494
gene_biotype: protein_coding
description:
  hipA-like N-terminal domain protein; [R] COG3550 Uncharacterized protein related to capsule biosynthesis enzymes.


ensembl_gene_id: OI25_4501
symbol: OI25_4501
gene_biotype: protein_coding
description:
  BGL: beta-galactosidase; [G] COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase.


ensembl_gene_id: OI25_4513
symbol: OI25_4513
gene_biotype: protein_coding
description:
  Polymer-forming cytoskeletal family protein; [M] COG1664 Integral membrane protein CcmA involved in cell shape determination.


ensembl_gene_id: OI25_4517
symbol: pyrB
gene_biotype: protein_coding
description:
  Asp_carb_tr: aspartate carbamoyltransferase; [F] COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: OI25_4520
symbol: OI25_4520
gene_biotype: protein_coding
description:
  tonB-siderophor: TonB-dependent siderophore receptor family protein; [P] COG4774 Outer membrane receptor for monomeric catechols.


ensembl_gene_id: OI25_4535
symbol: aepY
gene_biotype: protein_coding
description:
  ppyr-DeCO2ase: phosphonopyruvate decarboxylase; [EH] COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: OI25_454
symbol: OI25_454
gene_biotype: protein_coding
description:
  Calcineurin-like phosphoesterase family protein; [S] COG2908 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_4540
symbol: ftsI-2
gene_biotype: protein_coding
description:
  Penicillin binding transpeptidase domain protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: OI25_4553
symbol: OI25_4553
gene_biotype: protein_coding
description:
  wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family protein; [M] COG1922 Teichoic acid biosynthesis proteins; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: OI25_4557
symbol: OI25_4557
gene_biotype: protein_coding
description:
  Glycosyltransferase 25 family protein; [M] COG3306 Glycosyltransferase involved in LPS biosynthesis.


ensembl_gene_id: OI25_4559
symbol: OI25_4559
gene_biotype: protein_coding
description:
  NDP-sugDHase: nucleotide sugar dehydrogenase family protein; [M] COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: OI25_456
symbol: OI25_456
gene_biotype: protein_coding
description:
  Prokaryotic diacylglycerol kinase family protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: OI25_4561
symbol: OI25_4561
gene_biotype: protein_coding
description:
  Eps_transp_fam: exopolysaccharide transport family protein; [M] COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.


ensembl_gene_id: OI25_4568
symbol: oxlT
gene_biotype: protein_coding
description:
  oxa_formateAnti: oxalate/formate antiporter; [GEPR] COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: OI25_4573
symbol: frc
gene_biotype: protein_coding
description:
  formyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.


ensembl_gene_id: OI25_458
symbol: OI25_458
gene_biotype: protein_coding
description:
  Putative lysine decarboxylase family protein; [R] COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: OI25_4607
symbol: OI25_4607
gene_biotype: protein_coding
description:
  Putative glutaconate CoA-transferase subunit B; [I] COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit.


ensembl_gene_id: OI25_4608
symbol: OI25_4608
gene_biotype: protein_coding
description:
  Coenzyme A transferase family protein; [I] COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit.


ensembl_gene_id: OI25_4613
symbol: OI25_4613
gene_biotype: protein_coding
description:
  FAD binding domain protein; [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.


ensembl_gene_id: OI25_4615
symbol: OI25_4615
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase family protein; [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.


ensembl_gene_id: OI25_463
symbol: OI25_463
gene_biotype: protein_coding
description:
  ftsX-like permease family protein; [Q] COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component.


ensembl_gene_id: OI25_4633
symbol: OI25_4633
gene_biotype: protein_coding
description:
  ATPase associated with various cellular activities family protein; [O] COG0465 ATP-dependent Zn proteases; Belongs to the AAA ATPase family.


ensembl_gene_id: OI25_4640
symbol: kdpE
gene_biotype: protein_coding
description:
  KDP operon transcriptional regulatory protein kdpE; [TK] COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: OI25_4641
symbol: kdpC
gene_biotype: protein_coding
description:
  K+-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: OI25_4642
symbol: kdpB
gene_biotype: protein_coding
description:
  K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: OI25_4643
symbol: kdpA
gene_biotype: protein_coding
description:
  K+-transporting ATPase, A subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: OI25_4656
symbol: OI25_4656
gene_biotype: protein_coding
description:
  Hypothetical protein; Bacterial signalling N terminal repeat family protein; [T] COG3300 MHYT domain (predicted integral membrane sensor domain).


ensembl_gene_id: OI25_4658
symbol: OI25_4658
gene_biotype: protein_coding
description:
  Tetratricopeptide repeat family protein; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.


ensembl_gene_id: OI25_4659
symbol: OI25_4659
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [R] COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.


ensembl_gene_id: OI25_4661
symbol: OI25_4661
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; [R] COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: OI25_4666
symbol: OI25_4666
gene_biotype: protein_coding
description:
  Spermine/spermidine synthase family protein; [R] COG4262 Predicted spermidine synthase with an N-terminal membrane domain.


ensembl_gene_id: OI25_4667
symbol: OI25_4667
gene_biotype: protein_coding
description:
  Putative membrane protein; [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: OI25_4672
symbol: OI25_4672
gene_biotype: protein_coding
description:
  Outer membrane efflux family protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.


ensembl_gene_id: OI25_4676
symbol: OI25_4676
gene_biotype: protein_coding
description:
  Sugar-specific transcriptional regulator TrmB family protein; [KG] COG1940 Transcriptional regulator/sugar kinase.


ensembl_gene_id: OI25_4695
symbol: OI25_4695
gene_biotype: protein_coding
description:
  DSBA-like thioredoxin domain protein; [Q] COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: OI25_4696
symbol: OI25_4696
gene_biotype: protein_coding
description:
  Cupin domain protein; [S] COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: OI25_4700
symbol: OI25_4700
gene_biotype: protein_coding
description:
  Methyltransferase, family protein; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.


ensembl_gene_id: OI25_4708
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: OI25_4731
symbol: OI25_4731
gene_biotype: protein_coding
description:
  Bacterial regulatory s, tetR family protein; [K] COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: OI25_4741
symbol: OI25_4741
gene_biotype: protein_coding
description:
  Cupin domain protein; [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: OI25_4744
symbol: prpF
gene_biotype: protein_coding
description:
  prpF: putative AcnD-accessory protein PrpF; [S] COG2828 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_4746
symbol: OI25_4746
gene_biotype: protein_coding
description:
  cit_synth_II: 2-methylcitrate synthase/citrate synthase II family protein; [C] COG0372 Citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: OI25_4748
symbol: prpR
gene_biotype: protein_coding
description:
  propionate_PrpR: propionate catabolism operon regulatory protein PrpR; [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: OI25_4751
symbol: OI25_4751
gene_biotype: protein_coding
description:
  2Fe-2S iron-sulfur cluster binding domain protein; [R] COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: OI25_476
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: OI25_4766
symbol: OI25_4766
gene_biotype: protein_coding
description:
  Surface antigen variable number repeat family protein; [M] COG4775 Outer membrane protein/protective antigen OMA87.


ensembl_gene_id: OI25_4779
symbol: gabD-2
gene_biotype: protein_coding
description:
  SSADH: succinate-semialdehyde dehydrogenase family protein; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: OI25_478
symbol: purD
gene_biotype: protein_coding
description:
  purD: phosphoribosylamine--glycine ligase; [F] COG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family.


ensembl_gene_id: OI25_4787
symbol: OI25_4787
gene_biotype: protein_coding
description:
  Threonyl and Alanyl tRNA synthetase second additional domain protein; [R] COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.


ensembl_gene_id: OI25_479
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase family protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: OI25_4794
symbol: OI25_4794
gene_biotype: protein_coding
description:
  Transcriptional regulator PadR-like family protein; [K] COG1695 Predicted transcriptional regulators.


ensembl_gene_id: OI25_48
symbol: crcB
gene_biotype: protein_coding
description:
  crcB-like family protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: OI25_480
symbol: nadD
gene_biotype: protein_coding
description:
  Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: OI25_4801
symbol: OI25_4801
gene_biotype: protein_coding
description:
  hpcH/HpaI aldolase/citrate lyase family protein; [G] COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: OI25_4804
symbol: OI25_4804
gene_biotype: protein_coding
description:
  Bacterial regulatory, arsR family protein; [KG] COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: OI25_4807
symbol: pdxA-2
gene_biotype: protein_coding
description:
  pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA; [H] COG1995 Pyridoxal phosphate biosynthesis protein; Belongs to the PdxA family.


ensembl_gene_id: OI25_481
symbol: rsfS
gene_biotype: protein_coding
description:
  Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: OI25_482
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: OI25_483
symbol: maf-2
gene_biotype: protein_coding
description:
  Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: OI25_4856
symbol: OI25_4856
gene_biotype: protein_coding
description:
  Amidase family protein; [J] COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: OI25_4859
symbol: OI25_4859
gene_biotype: protein_coding
description:
  phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein; [P] COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: OI25_4860
symbol: phnW-3
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate--pyruvate transaminase; [E] COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase.


ensembl_gene_id: OI25_4862
symbol: OI25_4862
gene_biotype: protein_coding
description:
  phnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein; [P] COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: OI25_4863
symbol: OI25_4863
gene_biotype: protein_coding
description:
  phnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; [E] COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: OI25_487
symbol: OI25_487
gene_biotype: protein_coding
description:
  Esterase_phb: esterase, PHB depolymerase family protein; [Q] COG3509 Poly(3-hydroxybutyrate) depolymerase.


ensembl_gene_id: OI25_4871
symbol: coxB-2
gene_biotype: protein_coding
description:
  coxB: cytochrome c oxidase, subunit II; [C] COG1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2.


ensembl_gene_id: OI25_49
symbol: OI25_49
gene_biotype: protein_coding
description:
  Hypothetical protein; Domain of unknown function family protein; [S] COG5649 Uncharacterized conserved protein.


ensembl_gene_id: OI25_4905
symbol: OI25_4905
gene_biotype: protein_coding
description:
  Fasciclin domain protein; [M] COG2335 Secreted and surface protein containing fasciclin-like repeats.


ensembl_gene_id: OI25_4906
symbol: OI25_4906
gene_biotype: protein_coding
description:
  Lipocalin-like domain protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: OI25_4908
symbol: OI25_4908
gene_biotype: protein_coding
description:
  istB-like ATP binding family protein; [T] COG0467 RecA-superfamily ATPases implicated in signal transduction.


ensembl_gene_id: OI25_491
symbol: OI25_491
gene_biotype: protein_coding
description:
  Mop: molybdenum-pterin binding domain protein; [R] COG2005 N-terminal domain of molybdenum-binding protein.


ensembl_gene_id: OI25_4914
symbol: OI25_4914
gene_biotype: protein_coding
description:
  GAF domain protein; [T] COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase).


ensembl_gene_id: OI25_492
symbol: OI25_492
gene_biotype: protein_coding
description:
  SH3 domain of SH3b2 type family protein; [M] COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: OI25_4920
symbol: OI25_4920
gene_biotype: protein_coding
description:
  Nitrilase, sll0784 family; nitrile_sll0784: nitrilase, sll0784 family; [R] COG0388 Predicted amidohydrolase.


ensembl_gene_id: OI25_4923
symbol: OI25_4923
gene_biotype: protein_coding
description:
  Hypothetical protein; AIR synthase related, N-terminal domain protein; [R] COG2144 Selenophosphate synthetase-related proteins.


ensembl_gene_id: OI25_4927
symbol: OI25_4927
gene_biotype: protein_coding
description:
  Hypothetical protein; acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain protein; [I] COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit.


ensembl_gene_id: OI25_495
symbol: OI25_495
gene_biotype: protein_coding
description:
  Transglutaminase-like superfamily protein; [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: OI25_496
symbol: OI25_496
gene_biotype: protein_coding
description:
  Hypothetical protein; Bacterial transglutaminase-like N-terminal region family protein; [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: OI25_4983
symbol: urtC-2
gene_biotype: protein_coding
description:
  urea_trans_UrtC: urea ABC transporter, permease protein UrtC; [E] COG4177 ABC-type branched-chain amino acid transport system, permease component.


ensembl_gene_id: OI25_4984
symbol: urtB-2
gene_biotype: protein_coding
description:
  urea_trans_UrtB: urea ABC transporter, permease protein UrtB; [E] COG0559 Branched-chain amino acid ABC-type transport system, permease components.


ensembl_gene_id: OI25_4989
symbol: OI25_4989
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal domain protein; [C] COG2421 Predicted acetamidase/formamidase.


ensembl_gene_id: OI25_4991
symbol: OI25_4991
gene_biotype: protein_coding
description:
  HEQRo_perm_3TM: amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein; [E] COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: OI25_4998
symbol: yhdN
gene_biotype: protein_coding
description:
  General stress protein 69; [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: OI25_4999
symbol: OI25_4999
gene_biotype: protein_coding
description:
  Transcriptional regulator PadR-like family protein; [K] COG1733 Predicted transcriptional regulators.


ensembl_gene_id: OI25_5050
symbol: OI25_5050
gene_biotype: protein_coding
description:
  Luciferase-type oxidoreductase, BA3436 family protein; lucif_BA3436: luciferase-type oxidoreductase, BA3436 family protein; [C] COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: OI25_506
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: OI25_5066
symbol: OI25_5066
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase family protein; [C] COG1062 Zn-dependent alcohol dehydrogenases, class III.


ensembl_gene_id: OI25_5072
symbol: nadX
gene_biotype: protein_coding
description:
  Homoserine dehydrogenase, NAD binding domain protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.


ensembl_gene_id: OI25_509
symbol: OI25_509
gene_biotype: protein_coding
description:
  Rhodanese-like domain protein; [R] COG1054 Predicted sulfurtransferase; Belongs to the UPF0176 family.


ensembl_gene_id: OI25_510
symbol: gluQ
gene_biotype: protein_coding
description:
  Glutamyl-queuosine tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: OI25_5114
symbol: selB
gene_biotype: protein_coding
description:
  selB: selenocysteine-specific translation elongation factor; [J] COG3276 Selenocysteine-specific translation elongation factor.


ensembl_gene_id: OI25_5115
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: OI25_5116
symbol: fdhE
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: OI25_5117
symbol: OI25_5117
gene_biotype: protein_coding
description:
  formate-DH-gamm: formate dehydrogenase, gamma subunit; [C] COG2864 Cytochrome b subunit of formate dehydrogenase.


ensembl_gene_id: OI25_5118
symbol: fdxH
gene_biotype: protein_coding
description:
  FDH-beta: formate dehydrogenase, beta subunit; [C] COG0437 Fe-S-cluster-containing hydrogenase components 1.


ensembl_gene_id: OI25_5119
symbol: fdnG
gene_biotype: protein_coding
description:
  formate-DH-alph: formate dehydrogenase-N alpha subunit; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: OI25_5120
symbol: OI25_5120
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase Fe4S4 domain protein; [C] COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: OI25_5123
symbol: selU
gene_biotype: protein_coding
description:
  tRNA_sel_U_synt: tRNA 2-selenouridine synthase; [R] COG2603 Predicted ATPase; Belongs to the SelU family.


ensembl_gene_id: OI25_5128
symbol: OI25_5128
gene_biotype: protein_coding
description:
  2-pyrone-4,6-dicarboxylic acid hydrolase, putative; [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: OI25_5139
symbol: OI25_5139
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC); Belongs to the peptidase M81 family.


ensembl_gene_id: OI25_514
symbol: OI25_514
gene_biotype: protein_coding
description:
  Membrane-bound lysozyme-inhibitor of c-type lysozyme family protein; [R] COG3895 Predicted periplasmic protein.


ensembl_gene_id: OI25_5148
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: OI25_5158
symbol: OI25_5158
gene_biotype: protein_coding
description:
  Hypothetical protein; N-terminal half of MaoC dehydratase family protein; [S] COG3777 Uncharacterized conserved protein.


ensembl_gene_id: OI25_5159
symbol: OI25_5159
gene_biotype: protein_coding
description:
  Oxygenase, catalysing oxidative methylation of damaged DNA family protein; [S] COG3826 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_516
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: OI25_518
symbol: OI25_518
gene_biotype: protein_coding
description:
  ftsK/SpoIIIE family protein; [D] COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: OI25_5184
symbol: OI25_5184
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system / permease component family protein; [G] COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: OI25_5185
symbol: xylG-2
gene_biotype: protein_coding
description:
  D-xylose ABC transporter, ATP-binding protein; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.


ensembl_gene_id: OI25_5186
symbol: xylF
gene_biotype: protein_coding
description:
  xylF: D-xylose ABC transporter, D-xylose-binding protein; [G] COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: OI25_5187
symbol: xylA
gene_biotype: protein_coding
description:
  xylose_isom_A: xylose isomerase; [G] COG2115 Xylose isomerase; Belongs to the xylose isomerase family.


ensembl_gene_id: OI25_5210
symbol: mntH
gene_biotype: protein_coding
description:
  Metal ion transporter, metal ion family protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: OI25_5212
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: OI25_5215
symbol: OI25_5215
gene_biotype: protein_coding
description:
  Hypothetical protein; FAD linked oxidase, C-terminal domain protein; [C] COG0277 FAD/FMN-containing dehydrogenases.


ensembl_gene_id: OI25_5218
symbol: OI25_5218
gene_biotype: protein_coding
description:
  Glyoxalase-like domain protein; [ER] COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.


ensembl_gene_id: OI25_5220
symbol: pcaH
gene_biotype: protein_coding
description:
  Protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit; [Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit.


ensembl_gene_id: OI25_5221
symbol: pcaG
gene_biotype: protein_coding
description:
  Protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit; [Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit.


ensembl_gene_id: OI25_5227
symbol: OI25_5227
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding domain protein; [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: OI25_523
symbol: phaZ
gene_biotype: protein_coding
description:
  PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular family protein; [I] COG4553 Poly-beta-hydroxyalkanoate depolymerase.


ensembl_gene_id: OI25_5232
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: OI25_5236
symbol: tsaD
gene_biotype: protein_coding
description:
  tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: OI25_5238
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: OI25_5240
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: OI25_5245
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: OI25_525
symbol: OI25_525
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: OI25_5250
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: OI25_5252
symbol: thrB
gene_biotype: protein_coding
description:
  thrB_alt: homoserine kinase; [R] COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: OI25_5254
symbol: OI25_5254
gene_biotype: protein_coding
description:
  Hypothetical protein; Iron dependent repressor, N-terminal DNA binding domain protein; [K] COG1846 Transcriptional regulators.


ensembl_gene_id: OI25_5256
symbol: OI25_5256
gene_biotype: protein_coding
description:
  FAD binding domain of DNA photolyase family protein; [L] COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.


ensembl_gene_id: OI25_526
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: OI25_5260
symbol: modA
gene_biotype: protein_coding
description:
  modA: molybdate ABC transporter, periplasmic molybdate-binding protein; [P] COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: OI25_5261
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: OI25_5262
symbol: OI25_5262
gene_biotype: protein_coding
description:
  ABC transporter family protein; [P] COG1118 ABC-type sulfate/molybdate transport systems, ATPase component.


ensembl_gene_id: OI25_5268
symbol: argP
gene_biotype: protein_coding
description:
  argP: transcriptional regulator, ArgP family protein; [K] COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: OI25_5272
symbol: OI25_5272
gene_biotype: protein_coding
description:
  Calcineurin-like phosphoesterase family protein; [T] COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: OI25_5277
symbol: glgE
gene_biotype: protein_coding
description:
  Alpha amylase, catalytic domain protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: OI25_5279
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: OI25_5280
symbol: glgX
gene_biotype: protein_coding
description:
  glgX_debranch: glycogen debranching enzyme GlgX; [G] COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: OI25_5281
symbol: treZ
gene_biotype: protein_coding
description:
  trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase; [G] COG0296 1,4-alpha-glucan branching enzyme.


ensembl_gene_id: OI25_5290
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: OI25_5291
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: OI25_5294
symbol: folC
gene_biotype: protein_coding
description:
  folC: bifunctional FolC family protein; [H] COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: OI25_5295
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: OI25_5296
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: OI25_5298
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: OI25_5299
symbol: trpF
gene_biotype: protein_coding
description:
  N-(5'phosphoribosyl)anthranilate (PRA) isomerase family protein; [E] COG0135 Phosphoribosylanthranilate isomerase; Belongs to the TrpF family.


ensembl_gene_id: OI25_5300
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: OI25_5302
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: OI25_5303
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: OI25_5304
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: OI25_5306
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: OI25_5307
symbol: gltA
gene_biotype: protein_coding
description:
  cit_synth_I: citrate (Si)-synthase; [C] COG0372 Citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: OI25_5308
symbol: OI25_5308
gene_biotype: protein_coding
description:
  Flavinator of succinate dehydrogenase family protein; [S] COG2938 Uncharacterized conserved protein.


ensembl_gene_id: OI25_5309
symbol: sdhB
gene_biotype: protein_coding
description:
  dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur family protein; [C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.


ensembl_gene_id: OI25_531
symbol: OI25_531
gene_biotype: protein_coding
description:
  VWA domain containing CoxE-like family protein; [S] COG3825 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_5310
symbol: sdhA
gene_biotype: protein_coding
description:
  sdhA_forward: succinate dehydrogenase, flavoprotein subunit; [C] COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: OI25_5311
symbol: sdhD
gene_biotype: protein_coding
description:
  Succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein; [C] COG2142 Succinate dehydrogenase, hydrophobic anchor subunit.


ensembl_gene_id: OI25_5312
symbol: sdhC
gene_biotype: protein_coding
description:
  succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit; [C] COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.


ensembl_gene_id: OI25_5314
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: OI25_5318
symbol: prpD
gene_biotype: protein_coding
description:
  prpD: 2-methylcitrate dehydratase; [R] COG2079 Uncharacterized protein involved in propionate catabolism.


ensembl_gene_id: OI25_532
symbol: OI25_532
gene_biotype: protein_coding
description:
  benE: benzoate transporter family protein; [Q] COG3135 Uncharacterized protein involved in benzoate metabolism.


ensembl_gene_id: OI25_533
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: OI25_534
symbol: OI25_534
gene_biotype: protein_coding
description:
  glyoxalase/Bleomycin resistance /Dioxygenase superfamily protein; [S] COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: OI25_5365
symbol: OI25_5365
gene_biotype: protein_coding
description:
  Ureidoglycolate lyase; [Q] COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: OI25_5368
symbol: pld1
gene_biotype: protein_coding
description:
  Pyridoxal 4-dehydrogenase; [C] COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: OI25_5379
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: OI25_5382
symbol: OI25_5382
gene_biotype: protein_coding
description:
  Hypothetical protein; Pili and flagellar-assembly chaperone, PapD N-terminal domain protein; [NU] COG3121 P pilus assembly protein, chaperone PapD.


ensembl_gene_id: OI25_5391
symbol: OI25_5391
gene_biotype: protein_coding
description:
  AAA domain family protein; [KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: OI25_540
symbol: ubiC
gene_biotype: protein_coding
description:
  UTRA domain protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: OI25_5405
symbol: proV-2
gene_biotype: protein_coding
description:
  proV: glycine betaine/L-proline transport ATP binding subunit; [E] COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


