# pathwayInfo

id: PF16927
description: N-terminal 7TM region of histidine kinase
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16927
name:
  Protein Domains (Pfam).STRING_v12.0_1483599_STRINGid_PF16927_N-terminal_7TM_region_of_histidine_kinase


id: PF17144
description: Ribosomal large subunit proteins 60S L5, and 50S L18
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17144
name:
  Protein Domains (Pfam).STRING_v12.0_1483599_STRINGid_PF17144_Ribosomal_large_subunit_proteins_60S_L5,_and_50S_L18


id: PF17147
description: Pyruvate:ferredoxin oxidoreductase core domain II
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17147
name:
  Protein Domains (Pfam).STRING_v12.0_1483599_STRINGid_PF17147_Pyruvate:ferredoxin_oxidoreductase_core_domain_II


id: PF17432
description: Domain of unknown function (DUF3458_C) ARM repeats
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17432
name:
  Protein Domains (Pfam).STRING_v12.0_1483599_STRINGid_PF17432_Domain_of_unknown_function_(DUF3458_C)_ARM_repeats


id: SM00062
description: Bacterial periplasmic substrate-binding proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00062
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00062_Bacterial_periplasmic_substrate-binding_proteins


id: SM00065
description: Domain present in phytochromes and cGMP-specific phosphodiesterases.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00065
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00065_Domain_present_in_phytochromes_and_cGMP-specific_phosphodiesterases.


id: SM00086
description: Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00086
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00086_Motif_C-terminal_to_PAS_motifs_(likely_to_contribute_to_PAS_structural_domain)


id: SM00089
description: Repeats in polycystic kidney disease 1 (PKD1) and other proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00089
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00089_Repeats_in_polycystic_kidney_disease_1_(PKD1)_and_other_proteins


id: SM00116
description: Domain in cystathionine beta-synthase and other proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00116
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00116_Domain_in_cystathionine_beta-synthase_and_other_proteins.


id: SM00135
description: Low-density lipoprotein-receptor YWTD domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00135
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00135_Low-density_lipoprotein-receptor_YWTD_domain


id: SM00138
description: Methyltransferase, chemotaxis proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00138
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00138_Methyltransferase,_chemotaxis_proteins


id: SM00156
description: Protein phosphatase 2A homologues, catalytic domain.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00156
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00156_Protein_phosphatase_2A_homologues,_catalytic_domain.


id: SM00228
description: Domain present in PSD-95, Dlg, and ZO-1/2.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00228
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00228_Domain_present_in_PSD-95,_Dlg,_and_ZO-1/2.


id: SM00260
description: Two component signalling adaptor domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00260
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00260_Two_component_signalling_adaptor_domain


id: SM00271
description: DnaJ molecular chaperone homology domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00271
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00271_DnaJ_molecular_chaperone_homology_domain


id: SM00278
description: Helix-hairpin-helix DNA-binding motif class 1
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00278
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00278_Helix-hairpin-helix_DNA-binding_motif_class_1


id: SM00279
description: Helix-hairpin-helix class 2 (Pol1 family) motifs
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00279
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00279_Helix-hairpin-helix_class_2_(Pol1_family)_motifs


id: SM00283
description: Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00283
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00283_Methyl-accepting_chemotaxis-like_domains_(chemotaxis_sensory_transducer).


id: SM00304
description: HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00304
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00304_HAMP_(Histidine_kinases,_Adenylyl_cyclases,_Methyl_binding_proteins,_Phosphatases)_domain


id: SM00316
description: Ribosomal protein S1-like RNA-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00316
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00316_Ribosomal_protein_S1-like_RNA-binding_domain


id: SM00317
description: SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00317
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00317_SET_(Su(var)3-9,_Enhancer-of-zeste,_Trithorax)_domain


id: SM00327
description: Von Willebrand factor (vWF) type A domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00327
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00327_Von_Willebrand_factor_(vWF)_type_A_domain


id: SM00332
description: Serine/threonine phosphatases, family 2C, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00332
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00332_Serine/threonine_phosphatases,_family_2C,_catalytic_domain


id: SM00347
description: Helix_turn_helix multiple antibiotic resistance protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00347
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00347_Helix_turn_helix_multiple_antibiotic_resistance_protein


id: SM00359
description: Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00359
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00359_Putative_RNA-binding_Domain_in_PseudoUridine_synthase_and_Archaeosine_transglycosylase


id: SM00382
description: ATPases associated with a variety of cellular activities
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00382
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00382_ATPases_associated_with_a_variety_of_cellular_activities


id: SM00385
description: Domain present in cyclins, TFIIB and Retinoblastoma
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00385
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00385_Domain_present_in_cyclins,_TFIIB_and_Retinoblastoma


id: SM00418
description: Helix_turn_helix, Arsenical Resistance Operon Repressor
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00418
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00418_Helix_turn_helix,_Arsenical_Resistance_Operon_Repressor


id: SM00436
description: Bacterial DNA topoisomeraes I ATP-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00436
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00436_Bacterial_DNA_topoisomeraes_I_ATP-binding_domain


id: SM00437
description: Bacterial DNA topoisomerase I DNA-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00437
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00437_Bacterial_DNA_topoisomerase_I_DNA-binding_domain


id: SM00471
description: Metal dependent phosphohydrolases with conserved HD motif.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00471
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00471_Metal_dependent_phosphohydrolases_with_conserved_HD_motif.


id: SM00481
description: DNA polymerase alpha chain like domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00481
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00481_DNA_polymerase_alpha_chain_like_domain


id: SM00490
description: Helicase superfamily c-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00490
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00490_Helicase_superfamily_c-terminal_domain


id: SM00493
description: Topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00493
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00493_Topoisomerases,_DnaG-type_primases,_OLD_family_nucleases_and_RecR_proteins


id: SM00525
description: Iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00525
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00525_Iron-sulpphur_binding_domain_in_DNA-(apurinic_or_apyrimidinic_site)_lyase_(subfamily_of_ENDO3)


id: SM00529
description: Helix-turn-helix diphteria tox regulatory element
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00529
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00529_Helix-turn-helix_diphteria_tox_regulatory_element


id: SM00530
description: Helix-turn-helix XRE-family like proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00530
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00530_Helix-turn-helix_XRE-family_like_proteins


id: SM00533
description: DNA-binding domain of DNA mismatch repair MUTS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00533
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00533_DNA-binding_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00534
description: ATPase domain of DNA mismatch repair MUTS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00534
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00534_ATPase_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00554
description: Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00554
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00554_Four_repeated_domains_in_the_Fasciclin_I_family_of_proteins,_present_in_many_other_contexts.


id: SM00562
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00562
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00562_These_are_enzymes_that_catalyze_nonsubstrate_specific_conversions_of_nucleoside_diphosphates_to_nucleoside_triphosphates._These_enzymes_play_important_roles_in_bacterial_growth,_signal_transduction_and_pathogenicity.

description:
  These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.


id: SM00652
description: Eukaryotic translation initiation factor 1A
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00652
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00652_Eukaryotic_translation_initiation_factor_1A


id: SM00670
description: Large family of predicted nucleotide-binding domains
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00670
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00670_Large_family_of_predicted_nucleotide-binding_domains


id: SM00704
description: CDGSH-type zinc finger. Function unknown.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00704
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00704_CDGSH-type_zinc_finger._Function_unknown.


id: SM00722
description: Domain present in carbohydrate binding proteins and sugar hydrolses
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00722
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00722_Domain_present_in_carbohydrate_binding_proteins_and_sugar_hydrolses


id: SM00729
description: Elongator protein 3, MiaB family, Radical SAM
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00729
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00729_Elongator_protein_3,_MiaB_family,_Radical_SAM


id: SM00730
description: Presenilin, signal peptide peptidase, family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00730
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00730_Presenilin,_signal_peptide_peptidase,_family


id: SM00736
description: Dystroglycan-type cadherin-like domains.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00736
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00736_Dystroglycan-type_cadherin-like_domains.


id: SM00738
description: In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00738
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00738_In_Spt5p,_this_domain_may_confer_affinity_for_Spt4p._It_possesses_a_RNP-like_fold.


id: SM00739
description: KOW (Kyprides, Ouzounis, Woese) motif.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00739
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00739_KOW_(Kyprides,_Ouzounis,_Woese)_motif.


id: SM00758
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00758
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00758_Domain_in_bacterial_beta-glucosidases_other_glycosidases,_glycosyltransferases,_proteases,_amidases,_yeast_adhesins,_and_bacterial_toxins.

description:
  Domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins.


id: SM00790
description: Aldehyde ferredoxin oxidoreductase, N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00790
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00790_Aldehyde_ferredoxin_oxidoreductase,_N-terminal_domain


id: SM00839
description: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00839
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00839_Glutamate/Leucine/Phenylalanine/Valine_dehydrogenase


id: SM00840
description: This DALR domain is found in cysteinyl-tRNA-synthetases.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00840
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00840_This_DALR_domain_is_found_in_cysteinyl-tRNA-synthetases.


id: SM00846
description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00846
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00846_Glyceraldehyde_3-phosphate_dehydrogenase,_NAD_binding_domain


id: SM00859
description: Semialdehyde dehydrogenase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00859
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00859_Semialdehyde_dehydrogenase,_NAD_binding_domain


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00865
description: Tubulin/FtsZ family, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00865
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00865_Tubulin/FtsZ_family,_C-terminal_domain


id: SM00870
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00870
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00870_Asparaginase,_which_is_found_in_various_plant,_animal_and_bacterial_cells,_catalyses_the_deamination_of_asparagine_to_yield_aspartic_acid_and_an_ammonium_ion,_resulting_in_a_depletion_of_free_circulatory_asparagine_in_plasma_PUBMED:3026924._The_...

description:
  Asparaginase, which is found in various plant, animal and bacterial cells, catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma PUBMED:3026924. The ...


id: SM00871
description: Bacterial transcription activator, effector binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00871
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00871_Bacterial_transcription_activator,_effector_binding_domain


id: SM00876
description: Biotin and Thiamin Synthesis associated domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00876
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00876_Biotin_and_Thiamin_Synthesis_associated_domain


id: SM00879
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00879
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00879_The_Brix_domain_is_found_in_a_number_of_eukaryotic_proteins_including_SSF_proteins_from_yeast_and_humans,_Arabidopsis_thaliana_Peter_Pan-like_protein_and_several_hypothetical_proteins.

description:
  The Brix domain is found in a number of eukaryotic proteins including SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.


id: SM00880
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00880
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00880_The_CHAD_domain_is_an_alpha-helical_domain_functionally_associated_with_some_members_of_the_adenylate_cyclase_family_._It_has_conserved_histidines_that_may_chelate_metals.

description:
  The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family . It has conserved histidines that may chelate metals.


id: SM00888
description: EF-1 guanine nucleotide exchange domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00888
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00888_EF-1_guanine_nucleotide_exchange_domain


id: SM00899
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00899
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00899_This_entry_represents_the_core_domain_of_the_ferrous_iron_(Fe2+)_transport_protein_FeoA_found_in_bacteria._This_domain_also_occurs_at_the_C-terminus_in_related_proteins._The_transporter_Feo_is_composed_of_three_proteins:_FeoA_a_small,_soluble_...

description:
  This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble ...


id: SM00900
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00900
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00900_This_conserved_region_includes_the_FMN-binding_site_of_the_NqrC_protein_as_well_as_the_NosR_and_NirI_regulatory_proteins.

description:
  This conserved region includes the FMN-binding site of the NqrC protein as well as the NosR and NirI regulatory proteins.


id: SM00926
description: Molybdopterin oxidoreductase Fe4S4 domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00926
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00926_Molybdopterin_oxidoreductase_Fe4S4_domain


id: SM00933
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00933
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00933_This_family_includes_NurA_a_nuclease_exhibiting_both_single-stranded_endonuclease_activity_and_5-3_exonuclease_activity_on_single-stranded_and_double-stranded_DNA_from_the_hyperthermophilic_archaeon_Sulfolobus_acidocaldarius_PUBMED:12052775.

description:
  This family includes NurA a nuclease exhibiting both single-stranded endonuclease activity and 5-3 exonuclease activity on single-stranded and double-stranded DNA from the hyperthermophilic archaeon Sulfolobus acidocaldarius PUBMED:12052775.


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00941
description: Pyrimidine nucleoside phosphorylase C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00941
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00941_Pyrimidine_nucleoside_phosphorylase_C-terminal_domain


id: SM00948
description: Proteasome subunit A N-terminal signature Add an annotation
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00948
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00948_Proteasome_subunit_A_N-terminal_signature__Add_an_annotation


id: SM00953
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00953
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00953_This_presumed_protein_contains_3_highly_conserved_polar_groups_that_could_form_an_active_site._These_are_an_arginine,_glutamate_and_serine,_hence_the_RES_domain._RES_is_found_widely_distributed_in_bacteria,_it_has_about_150_residues_in_length.

description:
  This presumed protein contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. RES is found widely distributed in bacteria, it has about 150 residues in length.


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00956
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00956
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00956_This_DNA-binding_domain_is_found_in_the_RecQ_helicase_among_others_and_has_a_helix-turn-helix_structure._The_RQC_domain,_found_only_in_RecQ_family_enzymes,_is_a_high_affinity_G4_DNA_binding_domain_PUBMED:16530788.

description:
  This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain PUBMED:16530788.


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00981
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00989
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00989
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00989_The_V4R_(vinyl_4_reductase)_domain_is_a_predicted_small_molecular_binding_domain,_that_may_bind_to_hydrocarbons.

description:
  The V4R (vinyl 4 reductase) domain is a predicted small molecular binding domain, that may bind to hydrocarbons.


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01016
description: Arginyl tRNA synthetase N terminal dom
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01016
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01016_Arginyl_tRNA_synthetase_N_terminal_dom


id: SM01060
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01072
description: Cell division protein 48 (CDC48) domain 2
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01072
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01072_Cell_division_protein_48_(CDC48)_domain_2


id: SM01073
description: Cell division protein 48 (CDC48) N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01073
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01073_Cell_division_protein_48_(CDC48)_N-terminal_domain


id: SM01078
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01078
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01078_This_putative_domain_contains_a_quite_highly_conserved_sequence_of_CGGC_in_its_central_region._The_domain_has_many_conserved_cysteines_and_histidines_suggestive_of_a_zinc_binding_function.

description:
  This putative domain contains a quite highly conserved sequence of CGGC in its central region. The domain has many conserved cysteines and histidines suggestive of a zinc binding function.


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01103
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01103
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01103_Escherichia_coli_YhbY_is_associated_with_pre-50S_ribosomal_subunits,_which_implies_a_function_in_ribosome_assembly._GFP_fused_to_a_single-domain_CRM_protein_from_maize_localises_to_the_nucleolus,_suggesting_that_an_analogous_activity_may_have_been_...

description:
  Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly. GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been ...


id: SM01117
description: Cytochrome b5-like Heme/Steroid binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01117
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01117_Cytochrome_b5-like_Heme/Steroid_binding_domain


id: SM01118
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01118
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01118_These_sequences_are_functionally_identified_as_members_of_the_adenylate_cyclase_family,_which_catalyses_the_conversion_of_ATP_to_3,5-cyclic_AMP_and_pyrophosphate._Six_distinct_non-homologous_classes_of_AC_have_been_identified._The_structure_of_...

description:
  These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3,5-cyclic AMP and pyrophosphate. Six distinct non-homologous classes of AC have been identified. The structure of ...


id: SM01154
description: This family contains many hypothetical proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01154
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01154_This_family_contains_many_hypothetical_proteins.


id: SM01194
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01194
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01194_The_release_factor_eRF1_terminates_protein_biosynthesis_by_recognising_stop_codons_at_the_A_site_of_the_ribosome_and_stimulating_peptidyl-tRNA_bond_hydrolysis_at_the_peptidyl_transferase_centre._The_crystal_structure_of_human_eRF1_is_known_...

description:
  The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01230
description: Glutamine synthetase, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01230
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01230_Glutamine_synthetase,_catalytic_domain


id: SM01231
description: Signal transducing histidine kinase, homodimeric domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01231
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01231_Signal_transducing_histidine_kinase,_homodimeric_domain


id: SM01252
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01252
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01252_Conserved_DNA-binding_domain_that_is_found_in_a_wide_range_of_proteins_of_large_bacterial_and_eukaryotic_DNA_viruses.

description:
  Conserved DNA-binding domain that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses.


id: SM01325
description: This family of proteins has no known function.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01325
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01325_This_family_of_proteins_has_no_known_function.


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01376
description: Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01376
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01376_Eukaryotic_elongation_factor_5A_hypusine,_DNA-binding_OB_fold


id: SM01377
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01377
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01377_Bovine_L40_has_been_identified_as_a_secondary_RNA_binding_protein_(PMID:3129699)._L40_is_fused_to_a_ubiquitin_protein_(PMID:7488009).

description:
  Bovine L40 has been identified as a secondary RNA binding protein (PMID:3129699). L40 is fused to a ubiquitin protein (PMID:7488009).


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01393
description: This family includes ribosomal protein L32 from eukaryotes and archaebacteria.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01393
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01393_This_family_includes_ribosomal_protein_L32_from_eukaryotes_and_archaebacteria.


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01477
description: DDE transposase retroviral integrase sub-family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01477
name:
  Protein Domains (SMART).STRING_v12.0_1483599_STRINGid_SM01477_DDE_transposase_retroviral_integrase_sub-family


