# pathwayInfo

id: SM00865
description: Tubulin/FtsZ family, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00865
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00865_Tubulin/FtsZ_family,_C-terminal_domain


id: SM00866
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00866
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00866_The_UbiC_transcription_regulator-associated_(UTRA)_domain_is_a_conserved_ligand-binding_domain_that_has_a_similar_fold_to_PUBMED:12757941._It_is_believed_to_modulate_activity_of_bacterial_transcription_factors_in_response_to_binding_small_molecules.

description:
  The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.


id: SM00870
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00870
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00870_Asparaginase,_which_is_found_in_various_plant,_animal_and_bacterial_cells,_catalyses_the_deamination_of_asparagine_to_yield_aspartic_acid_and_an_ammonium_ion,_resulting_in_a_depletion_of_free_circulatory_asparagine_in_plasma_PUBMED:3026924._The_...

description:
  Asparaginase, which is found in various plant, animal and bacterial cells, catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma PUBMED:3026924. The ...


id: SM00871
description: Bacterial transcription activator, effector binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00871
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00871_Bacterial_transcription_activator,_effector_binding_domain


id: SM00880
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00880
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00880_The_CHAD_domain_is_an_alpha-helical_domain_functionally_associated_with_some_members_of_the_adenylate_cyclase_family_._It_has_conserved_histidines_that_may_chelate_metals.

description:
  The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family . It has conserved histidines that may chelate metals.


id: SM00895
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00895
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00895_This_entry_represents_the_C-terminal_ligand_binding_domain_of_many_members_of_the_GntR_family._This_domain_probably_binds_to_a_range_of_effector_molecules_that_regulate_the_transcription_of_genes_through_the_action_of_the_N-terminal_DNA-binding_...

description:
  This entry represents the C-terminal ligand binding domain of many members of the GntR family. This domain probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N-terminal DNA-binding ...


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00898
description: Formamidopyrimidine-DNA glycosylase N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00898
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00898_Formamidopyrimidine-DNA_glycosylase_N-terminal_domain


id: SM00899
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00899
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00899_This_entry_represents_the_core_domain_of_the_ferrous_iron_(Fe2+)_transport_protein_FeoA_found_in_bacteria._This_domain_also_occurs_at_the_C-terminus_in_related_proteins._The_transporter_Feo_is_composed_of_three_proteins:_FeoA_a_small,_soluble_...

description:
  This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble ...


id: SM00914
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00914
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00914_This_is_a_short_protein_of_unknown_function_it_is_found_at_the_C-terminus_of_proteins_in_the_UPF0302_family._It_is_named_after_the_sequence_of_the_most_conserved_region_in_some_members.

description:
  This is a short protein of unknown function it is found at the C-terminus of proteins in the UPF0302 family. It is named after the sequence of the most conserved region in some members.


id: SM00922
description: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00922
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00922_Mandelate_racemase_/_muconate_lactonizing_enzyme,_C-terminal_domain


id: SM00926
description: Molybdopterin oxidoreductase Fe4S4 domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00926
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00926_Molybdopterin_oxidoreductase_Fe4S4_domain


id: SM00929
description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00929
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00929_NADH-ubiquinone_oxidoreductase-G_iron-sulfur_binding_region


id: SM00930
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00930
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00930_This_domain_is_found_at_the_C-terminus_of_ABC_transporter_proteins_involved_in_D-methionine_transport_as_well_as_a_number_of_ferredoxin-like_proteins._This_domain_is_likely_to_act_as_a_substrate_binding_domain._The_domain_has_been_named_after_a_...

description:
  This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins. This domain is likely to act as a substrate binding domain. The domain has been named after a ...


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00939
description: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00939
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00939_X-Pro_dipeptidyl-peptidase_C-terminal_non-catalytic_domain


id: SM00941
description: Pyrimidine nucleoside phosphorylase C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00941
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00941_Pyrimidine_nucleoside_phosphorylase_C-terminal_domain


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00956
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00956
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00956_This_DNA-binding_domain_is_found_in_the_RecQ_helicase_among_others_and_has_a_helix-turn-helix_structure._The_RQC_domain,_found_only_in_RecQ_family_enzymes,_is_a_high_affinity_G4_DNA_binding_domain_PUBMED:16530788.

description:
  This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain PUBMED:16530788.


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00981
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00982
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00982
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00982_This_domain_is_found_in_proteins_necessary_for_strand-specific_repair_in_DNA_such_as_TRCF_in_Escherichia_coli._A_lesion_in_the_template_strand_blocks_the_RNA_polymerase_complex_(RNAP)._The_RNAP-DNA-RNA_complex_is_specifically_recognised_by_the_...

description:
  This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the ...


id: SM00983
description: Thiamin pyrophosphokinase, vitamin B1 binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00983
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00983_Thiamin_pyrophosphokinase,_vitamin_B1_binding_domain


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01016
description: Arginyl tRNA synthetase N terminal dom
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01016
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01016_Arginyl_tRNA_synthetase_N_terminal_dom


id: SM01022
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01022
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01022_The_ASCH_domain_adopts_a_beta-barrel_fold_similar_to_that_of_the_PUA_domain._It_is_thought_to_function_as_an_RNA-binding_domain_during_coactivation,_RNA-processing_and_possibly_during_prokaryotic_translation_regulation_PUBMED:16322048.

description:
  The ASCH domain adopts a beta-barrel fold similar to that of the PUA domain. It is thought to function as an RNA-binding domain during coactivation, RNA-processing and possibly during prokaryotic translation regulation PUBMED:16322048.


id: SM01060
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01103
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01103
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01103_Escherichia_coli_YhbY_is_associated_with_pre-50S_ribosomal_subunits,_which_implies_a_function_in_ribosome_assembly._GFP_fused_to_a_single-domain_CRM_protein_from_maize_localises_to_the_nucleolus,_suggesting_that_an_analogous_activity_may_have_been_...

description:
  Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly. GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been ...


id: SM01120
description: This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01120
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01120_This_domain_is_the_predicted_phosphatase_domain_of_the_dihydroxyacetone_kinase_family.


id: SM01121
description: This is the kinase domain of the dihydroxyacetone kinase family.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01121
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01121_This_is_the_kinase_domain_of_the_dihydroxyacetone_kinase_family.


id: SM01131
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01131
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01131_This_domain_is_often_found_adjacent_to_the_DHH_domain_PF01368_and_is_called_DHHA2_for_DHH_associated_domain._This_domain_is_diagnostic_of_DHH_subfamily_2_members_(PUBMED:9478130)._The_domain_is_about_120_residues_long_and_contains_a_conserved_DXK_...

description:
  This domain is often found adjacent to the DHH domain PF01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members (PUBMED:9478130). The domain is about 120 residues long and contains a conserved DXK ...


id: SM01149
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01149
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01149_This_family_contains_a_number_of_hypothetical_proteins_of_about_450_residues_in_length._Their_function_is_unknown,_and_most_are_bacterial._However,_structurally_this_family_is_part_of_the_6_hairpin_glycosidase_superfamily,_suggesting_a_glycosyl_...

description:
  This family contains a number of hypothetical proteins of about 450 residues in length. Their function is unknown, and most are bacterial. However, structurally this family is part of the 6 hairpin glycosidase superfamily, suggesting a glycosyl ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01230
description: Glutamine synthetase, catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01230
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01230_Glutamine_synthetase,_catalytic_domain


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01234
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01234
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01234_This_domain_has_haemolytic_activity_(PMID:19306042)._It_is_found_in_short_(73-103_amino_acid)_proteins_and_contains_three_conserved_cysteine_residues.

description:
  This domain has haemolytic activity (PMID:19306042). It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.


id: SM01245
description: This domain is found at the N-terminus of jag proteins.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01245
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01245_This_domain_is_found_at_the_N-terminus_of_jag_proteins.


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01434
description: PD-(D/E)XK nuclease transposase sub-family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01434
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01434_PD-(D/E)XK_nuclease_transposase_sub-family


id: SM01477
description: DDE transposase retroviral integrase sub-family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01477
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01477_DDE_transposase_retroviral_integrase_sub-family


id: SM01488
description: DDE transposase retroviral integrase sub-family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01488
name:
  Protein Domains (SMART).STRING_v12.0_1572701_STRINGid_SM01488_DDE_transposase_retroviral_integrase_sub-family


