# pathwayInfo

id: SM00228
description: Domain present in PSD-95, Dlg, and ZO-1/2.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00228
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00228_Domain_present_in_PSD-95,_Dlg,_and_ZO-1/2.


id: SM00271
description: DnaJ molecular chaperone homology domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00271
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00271_DnaJ_molecular_chaperone_homology_domain


id: SM00278
description: Helix-hairpin-helix DNA-binding motif class 1
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00278
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00278_Helix-hairpin-helix_DNA-binding_motif_class_1


id: SM00279
description: Helix-hairpin-helix class 2 (Pol1 family) motifs
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00279
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00279_Helix-hairpin-helix_class_2_(Pol1_family)_motifs


id: SM00316
description: Ribosomal protein S1-like RNA-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00316
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00316_Ribosomal_protein_S1-like_RNA-binding_domain


id: SM00327
description: Von Willebrand factor (vWF) type A domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00327
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00327_Von_Willebrand_factor_(vWF)_type_A_domain


id: SM00345
description: Helix_turn_helix gluconate operon transcriptional repressor
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00345
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00345_Helix_turn_helix_gluconate_operon_transcriptional_repressor


id: SM00359
description: Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00359
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00359_Putative_RNA-binding_Domain_in_PseudoUridine_synthase_and_Archaeosine_transglycosylase


id: SM00382
description: ATPases associated with a variety of cellular activities
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00382
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00382_ATPases_associated_with_a_variety_of_cellular_activities


id: SM00418
description: Helix_turn_helix, Arsenical Resistance Operon Repressor
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00418
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00418_Helix_turn_helix,_Arsenical_Resistance_Operon_Repressor


id: SM00419
description: Helix_turn_helix, cAMP Regulatory protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00419
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00419_Helix_turn_helix,_cAMP_Regulatory_protein


id: SM00436
description: Bacterial DNA topoisomeraes I ATP-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00436
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00436_Bacterial_DNA_topoisomeraes_I_ATP-binding_domain


id: SM00437
description: Bacterial DNA topoisomerase I DNA-binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00437
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00437_Bacterial_DNA_topoisomerase_I_DNA-binding_domain


id: SM00460
description: Transglutaminase/protease-like homologues
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00460
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00460_Transglutaminase/protease-like_homologues


id: SM00464
description: Found in ATP-dependent protease La (LON)
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00464
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00464_Found_in_ATP-dependent_protease_La_(LON)


id: SM00471
description: Metal dependent phosphohydrolases with conserved HD motif.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00471
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00471_Metal_dependent_phosphohydrolases_with_conserved_HD_motif.


id: SM00479
description: Exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other exonucleases
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00479
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00479_Exonuclease_domain_in_DNA-polymerase_alpha_and_epsilon_chain,_ribonuclease_T_and_other_exonucleases


id: SM00493
description: Topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00493
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00493_Topoisomerases,_DnaG-type_primases,_OLD_family_nucleases_and_RecR_proteins


id: SM00533
description: DNA-binding domain of DNA mismatch repair MUTS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00533
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00533_DNA-binding_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00534
description: ATPase domain of DNA mismatch repair MUTS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00534
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00534_ATPase_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00562
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00562
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00562_These_are_enzymes_that_catalyze_nonsubstrate_specific_conversions_of_nucleoside_diphosphates_to_nucleoside_triphosphates._These_enzymes_play_important_roles_in_bacterial_growth,_signal_transduction_and_pathogenicity.

description:
  These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.


id: SM00670
description: Large family of predicted nucleotide-binding domains
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00670
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00670_Large_family_of_predicted_nucleotide-binding_domains


id: SM00702
description: Prolyl 4-hydroxylase alpha subunit homologues.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00702
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00702_Prolyl_4-hydroxylase_alpha_subunit_homologues.


id: SM00729
description: Elongator protein 3, MiaB family, Radical SAM
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00729
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00729_Elongator_protein_3,_MiaB_family,_Radical_SAM


id: SM00756
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00756
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00756_Family_of_likely_enzymes_that_includes_the_catalytic_subunit_of_vitamin_K_epoxide_reductase._Bacterial_homologues_are_fused_to_members_of_the_thioredoxin_family_of_oxidoreductases.

description:
  Family of likely enzymes that includes the catalytic subunit of vitamin K epoxide reductase. Bacterial homologues are fused to members of the thioredoxin family of oxidoreductases.


id: SM00760
description: Bacterial dnaA protein helix-turn-helix domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00760
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00760_Bacterial_dnaA_protein_helix-turn-helix_domain


id: SM00833
description: Cobalamin synthesis protein cobW C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00833
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00833_Cobalamin_synthesis_protein_cobW_C-terminal_domain


id: SM00840
description: This DALR domain is found in cysteinyl-tRNA-synthetases.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00840
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00840_This_DALR_domain_is_found_in_cysteinyl-tRNA-synthetases.


id: SM00846
description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00846
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00846_Glyceraldehyde_3-phosphate_dehydrogenase,_NAD_binding_domain


id: SM00859
description: Semialdehyde dehydrogenase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00859
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00859_Semialdehyde_dehydrogenase,_NAD_binding_domain


id: SM00861
description: Transketolase, pyrimidine binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00861
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00861_Transketolase,_pyrimidine_binding_domain


id: SM00862
description: Transcriptional regulatory protein, C terminal
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00862
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00862_Transcriptional_regulatory_protein,_C_terminal


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00876
description: Biotin and Thiamin Synthesis associated domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00876
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00876_Biotin_and_Thiamin_Synthesis_associated_domain


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00898
description: Formamidopyrimidine-DNA glycosylase N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00898
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00898_Formamidopyrimidine-DNA_glycosylase_N-terminal_domain


id: SM00922
description: Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00922
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00922_Mandelate_racemase_/_muconate_lactonizing_enzyme,_C-terminal_domain


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00939
description: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00939
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00939_X-Pro_dipeptidyl-peptidase_C-terminal_non-catalytic_domain


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00974
description: This entry represents the putative helicase A859L PUBMED:11897024.
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00974
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00974_This_entry_represents_the_putative_helicase_A859L_PUBMED:11897024.


id: SM00981
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00982
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00982
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00982_This_domain_is_found_in_proteins_necessary_for_strand-specific_repair_in_DNA_such_as_TRCF_in_Escherichia_coli._A_lesion_in_the_template_strand_blocks_the_RNA_polymerase_complex_(RNAP)._The_RNAP-DNA-RNA_complex_is_specifically_recognised_by_the_...

description:
  This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the ...


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00988
description: UreE urease accessory protein, N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00988
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00988_UreE_urease_accessory_protein,_N-terminal_domain


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01116
description: Cyanate lyase C-terminal domain, Cyanate hydratase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01116
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01116_Cyanate_lyase_C-terminal_domain,_Cyanate_hydratase


id: SM01118
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01118
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01118_These_sequences_are_functionally_identified_as_members_of_the_adenylate_cyclase_family,_which_catalyses_the_conversion_of_ATP_to_3,5-cyclic_AMP_and_pyrophosphate._Six_distinct_non-homologous_classes_of_AC_have_been_identified._The_structure_of_...

description:
  These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3,5-cyclic AMP and pyrophosphate. Six distinct non-homologous classes of AC have been identified. The structure of ...


id: SM01142
description: This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases [PUBMED:15112237].
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01142
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01142_This_C_terminal_domain_is_found_in_DOB1/SK12/helY-like_DEAD_box_helicases_[PUBMED:15112237].


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01234
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01234
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01234_This_domain_has_haemolytic_activity_(PMID:19306042)._It_is_found_in_short_(73-103_amino_acid)_proteins_and_contains_three_conserved_cysteine_residues.

description:
  This domain has haemolytic activity (PMID:19306042). It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.


id: SM01248
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01248
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01248_The_cyanobacterial_clock_proteins_KaiA_and_KaiB_are_proposed_as_regulators_of_the_circadian_rhythm_in_cyanobacteria._Mutations_in_both_proteins_have_been_reported_to_alter_or_abolish_circadian_rhythmicity._KaiB_adopts_an_alpha-beta_meander_motif_and_...

description:
  The cyanobacterial clock proteins KaiA and KaiB are proposed as regulators of the circadian rhythm in cyanobacteria. Mutations in both proteins have been reported to alter or abolish circadian rhythmicity. KaiB adopts an alpha-beta meander motif and ...


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: https://smart.embl.de/smart/do_annotation.pl?ACC=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_167548_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


