# geneInfo

ensembl_gene_id: HMPREF9952_0003
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: HMPREF9952_0004
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: HMPREF9952_0005
symbol: sun
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: HMPREF9952_0007
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: HMPREF9952_0008
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: HMPREF9952_0009
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: HMPREF9952_0010
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: HMPREF9952_0011
symbol: EGV06251.1
gene_biotype: protein_coding
description:
  Peptidase, M16 family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the peptidase M16 family.


ensembl_gene_id: HMPREF9952_0012
symbol: PqqL
gene_biotype: protein_coding
description:
  Peptidase M16 inactive domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0013
symbol: EGV06248.1
gene_biotype: protein_coding
description:
  HAD phosphatase, family IIIB domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0017
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: HMPREF9952_0018
symbol: rpsB
gene_biotype: protein_coding
description:
  30S ribosomal protein S2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: HMPREF9952_0019
symbol: EGV06254.1
gene_biotype: protein_coding
description:
  Ribosomal protein S2 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0024
symbol: rnr
gene_biotype: protein_coding
description:
  An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the RNR ribonuclease family.


ensembl_gene_id: HMPREF9952_0025
symbol: EGV06283.1
gene_biotype: protein_coding
description:
  S1 RNA binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0026
symbol: rlmB
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: HMPREF9952_0027
symbol: brnQ_1
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: HMPREF9952_0028
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: HMPREF9952_0029
symbol: emrA
gene_biotype: protein_coding
description:
  Multidrug resistance protein A; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0031
symbol: EGV06262.1
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0032
symbol: EGV06234.1
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter DcuB domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0033
symbol: DcuB
gene_biotype: protein_coding
description:
  Putative anaerobic C4-dicarboxylate transporter DcuB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0034
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: HMPREF9952_0036
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: HMPREF9952_0037
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: HMPREF9952_0040
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: HMPREF9952_0042
symbol: Mip
gene_biotype: protein_coding
description:
  Peroxidase-like protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: HMPREF9952_0045
symbol: YbhI
gene_biotype: protein_coding
description:
  2-oxoglutarate/malate translocator; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0046
symbol: EGV06239.1
gene_biotype: protein_coding
description:
  Sodium:sulfate symporter transmembrane region domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0047
symbol: htpX
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0048
symbol: EGV06307.1
gene_biotype: protein_coding
description:
  Heat shock protein HtpX domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0050
symbol: EGV06268.1
gene_biotype: protein_coding
description:
  Oxidoreductase, FAD/FMN dependent; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0054
symbol: potD_1
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein PotD; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: HMPREF9952_0055
symbol: proS
gene_biotype: protein_coding
description:
  proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]


ensembl_gene_id: HMPREF9952_0057
symbol: WaaQ
gene_biotype: protein_coding
description:
  Heptosyltransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0058
symbol: EGV06261.1
gene_biotype: protein_coding
description:
  Heptosyltransferase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0060
symbol: RfaL
gene_biotype: protein_coding
description:
  O-antigen ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0062
symbol: fbaA
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: HMPREF9952_0069
symbol: LpxH
gene_biotype: protein_coding
description:
  Putative UDP-2,3-diacylglucosamine hydrolase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0070
symbol: EGV06257.1
gene_biotype: protein_coding
description:
  Ser/Thr phosphatase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0071
symbol: EGV06286.1
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0072
symbol: plsC
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0073
symbol: ftsP
gene_biotype: protein_coding
description:
  Multicopper oxidase; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.


ensembl_gene_id: HMPREF9952_0076
symbol: EGV06222.1
gene_biotype: protein_coding
description:
  Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0077
symbol: PgmB
gene_biotype: protein_coding
description:
  Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the phosphohexose mutase family.


ensembl_gene_id: HMPREF9952_0079
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: HMPREF9952_0080
symbol: EGV06276.1
gene_biotype: protein_coding
description:
  Putative O-succinylbenzoate synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0081
symbol: MenC
gene_biotype: protein_coding
description:
  O-succinylbenzoate synthase-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: HMPREF9952_0082
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: HMPREF9952_0083
symbol: accB
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: HMPREF9952_0084
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: HMPREF9952_0091
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: HMPREF9952_0092
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: HMPREF9952_0093
symbol: fis
gene_biotype: protein_coding
description:
  DNA-binding protein Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: HMPREF9952_0100
symbol: smpA
gene_biotype: protein_coding
description:
  Small protein A; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: HMPREF9952_0103
symbol: cpxA
gene_biotype: protein_coding
description:
  Sensor protein CpxA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0104
symbol: EGV06306.1
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_0109
symbol: SpkB
gene_biotype: protein_coding
description:
  Pentapeptide repeat protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0110
symbol: cueR
gene_biotype: protein_coding
description:
  Cu(I)-responsive transcriptional regulator; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0112
symbol: EGV06477.1
gene_biotype: protein_coding
description:
  Heavy metal-associated domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0113
symbol: CopA
gene_biotype: protein_coding
description:
  Copper-exporting ATPase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0114
symbol: metJ
gene_biotype: protein_coding
description:
  Met Apo-repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.


ensembl_gene_id: HMPREF9952_0115
symbol: aqpZ
gene_biotype: protein_coding
description:
  Aquaporin Z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: HMPREF9952_0117
symbol: EGV06588.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase SrmB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0119
symbol: SrmB
gene_biotype: protein_coding
description:
  Type III restriction enzyme, res subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0120
symbol: YfiC
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase-like protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: HMPREF9952_0121
symbol: EGV06554.1
gene_biotype: protein_coding
description:
  TonB-dependent receptor; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0122
symbol: EGV06551.1
gene_biotype: protein_coding
description:
  Outer membrane receptor-mediated transport energizer protein TonB family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0126
symbol: EGV06473.1
gene_biotype: protein_coding
description:
  RQC domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0127
symbol: RecQ
gene_biotype: protein_coding
description:
  Putative ATP-dependent DNA helicase RecQ; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0128
symbol: EGV06479.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0129
symbol: cyaY
gene_biotype: protein_coding
description:
  Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: HMPREF9952_0131
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: HMPREF9952_0134
symbol: napB
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, diheme cytochrome c subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: HMPREF9952_0137
symbol: napG
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapG; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0138
symbol: napA
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: HMPREF9952_0139
symbol: napD
gene_biotype: protein_coding
description:
  NapD protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: HMPREF9952_0140
symbol: napF
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: HMPREF9952_0142
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: HMPREF9952_0143
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: HMPREF9952_0146
symbol: EGV06515.1
gene_biotype: protein_coding
description:
  Sporulation and cell division repeat domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0148
symbol: MexA
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: HMPREF9952_0149
symbol: EGV06526.1
gene_biotype: protein_coding
description:
  RND transporter, HAE1/HME family, permease protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: HMPREF9952_0151
symbol: SdcS_2
gene_biotype: protein_coding
description:
  TrkA C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0152
symbol: EGV06601.1
gene_biotype: protein_coding
description:
  Citrate transporter domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0154
symbol: EGV06480.1
gene_biotype: protein_coding
description:
  Ribonuclease HII-like protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: HMPREF9952_0155
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: HMPREF9952_0156
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: HMPREF9952_0157
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: HMPREF9952_0158
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: HMPREF9952_0160
symbol: yaeT
gene_biotype: protein_coding
description:
  Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: HMPREF9952_0161
symbol: EGV06490.1
gene_biotype: protein_coding
description:
  Peptidase, M50 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0162
symbol: RseP
gene_biotype: protein_coding
description:
  Putative RIP metalloprotease RseP; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0164
symbol: uppS
gene_biotype: protein_coding
description:
  Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: HMPREF9952_0165
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: HMPREF9952_0166
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: HMPREF9952_0169
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: HMPREF9952_0170
symbol: EGV06475.1
gene_biotype: protein_coding
description:
  DHHA1 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0171
symbol: alaS
gene_biotype: protein_coding
description:
  alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: HMPREF9952_0172
symbol: UspA
gene_biotype: protein_coding
description:
  Universal stress family protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.


ensembl_gene_id: HMPREF9952_0173
symbol: PepP_1
gene_biotype: protein_coding
description:
  Metallopeptidase family M24; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the peptidase M24B family.


ensembl_gene_id: HMPREF9952_0174
symbol: EGV06567.1
gene_biotype: protein_coding
description:
  Aminopeptidase P, N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0176
symbol: mreD
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: HMPREF9952_0178
symbol: ftsA_1
gene_biotype: protein_coding
description:
  Cell division protein FtsA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0179
symbol: YddA_2
gene_biotype: protein_coding
description:
  ABC transporter transmembrane region 2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0182
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: HMPREF9952_0183
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: HMPREF9952_0184
symbol: EGV06514.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein dimerization domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0185
symbol: EGV06618.1
gene_biotype: protein_coding
description:
  Putative penicillin-binding protein 2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0186
symbol: PbpA
gene_biotype: protein_coding
description:
  Penicillin-binding protein, transpeptidase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0187
symbol: MrdB
gene_biotype: protein_coding
description:
  Putative rod shape-determining protein RodA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the SEDS family.


ensembl_gene_id: HMPREF9952_0188
symbol: EGV06562.1
gene_biotype: protein_coding
description:
  Cell cycle protein, FtsW/RodA/SpoVE domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the SEDS family.


ensembl_gene_id: HMPREF9952_0189
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: HMPREF9952_0192
symbol: LipB
gene_biotype: protein_coding
description:
  Putative lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.


ensembl_gene_id: HMPREF9952_0193
symbol: EGV06516.1
gene_biotype: protein_coding
description:
  Octanoyltransferase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0194
symbol: lipA
gene_biotype: protein_coding
description:
  Putative lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: HMPREF9952_0195
symbol: EGV06533.1
gene_biotype: protein_coding
description:
  Putative lipoyl synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0197
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: HMPREF9952_0198
symbol: yfiO
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfiO; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: HMPREF9952_0199
symbol: YqgF
gene_biotype: protein_coding
description:
  RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: HMPREF9952_0201
symbol: rsmE
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase RsmE; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0202
symbol: EGV06489.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmE domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0203
symbol: fadR
gene_biotype: protein_coding
description:
  Fatty acid metabolism transcriptional regulator FadR; Multifunctional regulator of fatty acid metabolism.


ensembl_gene_id: HMPREF9952_0204
symbol: nhaB
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: HMPREF9952_0205
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: HMPREF9952_0209
symbol: EGV06572.1
gene_biotype: protein_coding
description:
  Glycosyltransferase, group 2 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0210
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: HMPREF9952_0211
symbol: EGV06553.1
gene_biotype: protein_coding
description:
  Acyltransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0212
symbol: EGV06476.1
gene_biotype: protein_coding
description:
  Conserved domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0213
symbol: BexB
gene_biotype: protein_coding
description:
  ABC-2 type transporter; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0218
symbol: EGV06611.1
gene_biotype: protein_coding
description:
  WavE lipopolysaccharide synthesis domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0223
symbol: EGV06485.1
gene_biotype: protein_coding
description:
  Putative UDP-galactopyranose mutase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0228
symbol: rfbB
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: HMPREF9952_0230
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside pyrophosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: HMPREF9952_0232
symbol: pgaC
gene_biotype: protein_coding
description:
  Poly-beta-1,6 N-acetyl-D-glucosamine synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0237
symbol: EGV06582.1
gene_biotype: protein_coding
description:
  ZIP zinc transporter family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0238
symbol: ZupT
gene_biotype: protein_coding
description:
  Metal cation transporter, ZIP domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0240
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase 1; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: HMPREF9952_0241
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: HMPREF9952_0245
symbol: secA
gene_biotype: protein_coding
description:
  Protein translocase subunit secA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0246
symbol: SecA
gene_biotype: protein_coding
description:
  Putative preprotein translocase, SecA subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0251
symbol: lptE
gene_biotype: protein_coding
description:
  Putative LPS-assembly lipoprotein RlpB; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: HMPREF9952_0252
symbol: LeuS
gene_biotype: protein_coding
description:
  Putative leucine--tRNA ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0256
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: HMPREF9952_0257
symbol: EGV05450.1
gene_biotype: protein_coding
description:
  Putative lipoprotein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0261
symbol: EGV05507.1
gene_biotype: protein_coding
description:
  Glycosyltransferase family 28 C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_0262
symbol: EGV05438.1
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_0263
symbol: nqrA
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: HMPREF9952_0264
symbol: nqrB
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, B subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: HMPREF9952_0265
symbol: nqrC
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: HMPREF9952_0266
symbol: nqrD
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, D subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: HMPREF9952_0267
symbol: NqrE
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, E subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: HMPREF9952_0268
symbol: EGV05556.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, E subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0269
symbol: nqrF
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, F subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: HMPREF9952_0270
symbol: ApbE
gene_biotype: protein_coding
description:
  ApbE domain protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: HMPREF9952_0271
symbol: EGV05570.1
gene_biotype: protein_coding
description:
  ApbE domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0273
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: HMPREF9952_0274
symbol: EGV05575.1
gene_biotype: protein_coding
description:
  BCCT family transporter domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: HMPREF9952_0276
symbol: BetP_2
gene_biotype: protein_coding
description:
  Transporter, betaine/carnitine/choline family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: HMPREF9952_0278
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: HMPREF9952_0279
symbol: tatB
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: HMPREF9952_0280
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: HMPREF9952_0281
symbol: hemB
gene_biotype: protein_coding
description:
  Porphobilinogen synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the ALAD family.


ensembl_gene_id: HMPREF9952_0282
symbol: GdhA
gene_biotype: protein_coding
description:
  Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: HMPREF9952_0284
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: HMPREF9952_0285
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: HMPREF9952_0286
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: HMPREF9952_0287
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: HMPREF9952_0291
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: HMPREF9952_0292
symbol: grcA
gene_biotype: protein_coding
description:
  Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.


ensembl_gene_id: HMPREF9952_0295
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: HMPREF9952_0297
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: HMPREF9952_0298
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: HMPREF9952_0301
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: HMPREF9952_0302
symbol: gloA
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: HMPREF9952_0304
symbol: EGV05462.1
gene_biotype: protein_coding
description:
  Conserved domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_0306
symbol: EGV05589.1
gene_biotype: protein_coding
description:
  Putative membrane protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0307
symbol: cmoA
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: HMPREF9952_0308
symbol: aspS
gene_biotype: protein_coding
description:
  aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: HMPREF9952_0310
symbol: nudB
gene_biotype: protein_coding
description:
  Dihydroneopterin triphosphate pyrophosphatase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0313
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: HMPREF9952_0314
symbol: EGV05521.1
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0315
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Belongs to the RuvA family.


ensembl_gene_id: HMPREF9952_0316
symbol: EGV05463.1
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase RuvB domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0317
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: HMPREF9952_0320
symbol: CydB
gene_biotype: protein_coding
description:
  Cytochrome d ubiquinol oxidase, subunit II-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0324
symbol: tolQ
gene_biotype: protein_coding
description:
  Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: HMPREF9952_0325
symbol: tolR
gene_biotype: protein_coding
description:
  Transport energizing protein, ExbD/TolR family; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: HMPREF9952_0327
symbol: tolB
gene_biotype: protein_coding
description:
  Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: HMPREF9952_0328
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: HMPREF9952_0333
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: HMPREF9952_0334
symbol: iscR
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly transcription factor IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: HMPREF9952_0335
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: HMPREF9952_0336
symbol: iscU
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: HMPREF9952_0337
symbol: iscA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: HMPREF9952_0338
symbol: hscB
gene_biotype: protein_coding
description:
  Fe-S protein assembly co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: HMPREF9952_0341
symbol: hscA
gene_biotype: protein_coding
description:
  Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: HMPREF9952_0342
symbol: fdx
gene_biotype: protein_coding
description:
  Ferredoxin, 2Fe-2S type, ISC system; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0344
symbol: galT
gene_biotype: protein_coding
description:
  UTP--hexose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.


ensembl_gene_id: HMPREF9952_0350
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: HMPREF9952_0353
symbol: EGV05526.1
gene_biotype: protein_coding
description:
  Phospholipase, patatin domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0358
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.


ensembl_gene_id: HMPREF9952_0359
symbol: EGV05418.1
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0365
symbol: EGV05405.1
gene_biotype: protein_coding
description:
  BolA-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the BolA/IbaG family.


ensembl_gene_id: HMPREF9952_0366
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: HMPREF9952_0368
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: HMPREF9952_0369
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0370
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: HMPREF9952_0375
symbol: hisC_1
gene_biotype: protein_coding
description:
  Histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: HMPREF9952_0377
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: HMPREF9952_0378
symbol: EGV05567.1
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0379
symbol: HisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.


ensembl_gene_id: HMPREF9952_0384
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 thiotransferase enzyme MiaB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0385
symbol: EGV05423.1
gene_biotype: protein_coding
description:
  (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0386
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: HMPREF9952_0387
symbol: EGV05535.1
gene_biotype: protein_coding
description:
  Cytochrome c assembly protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0390
symbol: sodA
gene_biotype: protein_coding
description:
  Superoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: HMPREF9952_0391
symbol: ccmA
gene_biotype: protein_coding
description:
  Heme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: HMPREF9952_0392
symbol: ccmB
gene_biotype: protein_coding
description:
  Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: HMPREF9952_0393
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein C; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: HMPREF9952_0394
symbol: ccmD
gene_biotype: protein_coding
description:
  Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: HMPREF9952_0395
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome C-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: HMPREF9952_0396
symbol: CcmF_2
gene_biotype: protein_coding
description:
  Putative cytochrome c-type biogenesis protein CcmF; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0401
symbol: CcmH2
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmI-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0405
symbol: rlmM
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase J-like protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: HMPREF9952_0406
symbol: gcvA
gene_biotype: protein_coding
description:
  Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF9952_0413
symbol: EGV05596.1
gene_biotype: protein_coding
description:
  Cystathionine gamma-synthase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0414
symbol: EGV05380.1
gene_biotype: protein_coding
description:
  Putative cystathionine gamma-synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0415
symbol: metB
gene_biotype: protein_coding
description:
  Cystathionine gamma-synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0419
symbol: EGV05543.1
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0420
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the UPRTase family.


ensembl_gene_id: HMPREF9952_0423
symbol: YhhQ
gene_biotype: protein_coding
description:
  Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: HMPREF9952_0427
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: HMPREF9952_0429
symbol: pth
gene_biotype: protein_coding
description:
  aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: HMPREF9952_0430
symbol: Dat
gene_biotype: protein_coding
description:
  Putative diaminobutyrate--2-oxoglutarate transaminase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: HMPREF9952_0431
symbol: EGV05447.1
gene_biotype: protein_coding
description:
  Putative diaminobutyrate--2-oxoglutarate transaminase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0436
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: HMPREF9952_0439
symbol: cpdA
gene_biotype: protein_coding
description:
  3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: HMPREF9952_0441
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: HMPREF9952_0443
symbol: ArtI_1
gene_biotype: protein_coding
description:
  Putative ABC transporter arginine-binding protein 2; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HMPREF9952_0444
symbol: ArtI_2
gene_biotype: protein_coding
description:
  Lysine-arginine-ornithine-binding periplasmic protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HMPREF9952_0447
symbol: EGV05519.1
gene_biotype: protein_coding
description:
  NAD-dependent deacetylase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0448
symbol: EGV05524.1
gene_biotype: protein_coding
description:
  Putative NAD-dependent deacetylase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0449
symbol: npdA
gene_biotype: protein_coding
description:
  NAD-dependent deacetylase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0451
symbol: CstA
gene_biotype: protein_coding
description:
  Carbon starvation protein CstA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0453
symbol: EGV05529.1
gene_biotype: protein_coding
description:
  MraZ domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0454
symbol: mraZ
gene_biotype: protein_coding
description:
  Putative protein MraZ; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the MraZ family.


ensembl_gene_id: HMPREF9952_0455
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: HMPREF9952_0456
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: HMPREF9952_0459
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: HMPREF9952_0460
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: HMPREF9952_0461
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: HMPREF9952_0462
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: HMPREF9952_0463
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: HMPREF9952_0464
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: HMPREF9952_0466
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: HMPREF9952_0467
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: HMPREF9952_0468
symbol: ftsA_2
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: HMPREF9952_0469
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: HMPREF9952_0470
symbol: LpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase-like protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family.


ensembl_gene_id: HMPREF9952_0471
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family.


ensembl_gene_id: HMPREF9952_0473
symbol: ushA
gene_biotype: protein_coding
description:
  Bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: HMPREF9952_0475
symbol: cmoB
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: HMPREF9952_0484
symbol: cysS
gene_biotype: protein_coding
description:
  cysteine--tRNA ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0485
symbol: EGV05541.1
gene_biotype: protein_coding
description:
  Putative cysteine--tRNA ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0486
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: HMPREF9952_0488
symbol: nrdG
gene_biotype: protein_coding
description:
  Class III anaerobic ribonucleotide reductase small component; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0491
symbol: EGV05549.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0492
symbol: EGV05630.1
gene_biotype: protein_coding
description:
  Cysteine/glutathione ABC transporter membrane/ATP-binding component; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0493
symbol: CydD
gene_biotype: protein_coding
description:
  Putative cysteine/glutathione ABC transporter membrane/ATP-binding component; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0494
symbol: EGV05474.1
gene_biotype: protein_coding
description:
  Thioredoxin-disulfide reductase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0495
symbol: TrxB
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0502
symbol: EGV05602.1
gene_biotype: protein_coding
description:
  Selenide, water dikinase-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_0503
symbol: SelD
gene_biotype: protein_coding
description:
  Selenide, water dikinase-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0505
symbol: FldA_2
gene_biotype: protein_coding
description:
  Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: HMPREF9952_0507
symbol: seqA
gene_biotype: protein_coding
description:
  SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: HMPREF9952_0510
symbol: EGV05517.1
gene_biotype: protein_coding
description:
  Transporter, small conductance mechanosensitive ion channel MscS family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0511
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: HMPREF9952_0512
symbol: mepA
gene_biotype: protein_coding
description:
  Peptidoglycan amidase MepA; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.


ensembl_gene_id: HMPREF9952_0513
symbol: YfcA
gene_biotype: protein_coding
description:
  Sulfite exporter TauE/SafE domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0515
symbol: msbB
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: HMPREF9952_0516
symbol: arcB
gene_biotype: protein_coding
description:
  Aerobic respiration control sensor protein ArcB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0517
symbol: EGV05432.1
gene_biotype: protein_coding
description:
  Hpt domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0518
symbol: tmcA
gene_biotype: protein_coding
description:
  Putative ATPase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: HMPREF9952_0520
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: HMPREF9952_0527
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: HMPREF9952_0528
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: HMPREF9952_0529
symbol: ribD
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: HMPREF9952_0531
symbol: YfbR
gene_biotype: protein_coding
description:
  HD domain protein; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: HMPREF9952_0535
symbol: htrB
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: HMPREF9952_0536
symbol: rfaE
gene_biotype: protein_coding
description:
  Bifunctional protein RfaE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: HMPREF9952_0537
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: HMPREF9952_0538
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: HMPREF9952_0540
symbol: adh
gene_biotype: protein_coding
description:
  Aldehyde-alcohol dehydrogenase 2; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: HMPREF9952_0549
symbol: EGV04978.1
gene_biotype: protein_coding
description:
  Cation transport domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0552
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfur transfer protein SirA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: HMPREF9952_0555
symbol: SelB
gene_biotype: protein_coding
description:
  Putative selenocysteine-specific translation elongation factor; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0556
symbol: EGV04972.1
gene_biotype: protein_coding
description:
  Elongation factor Tu GTP binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0557
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: HMPREF9952_0567
symbol: EGV04991.1
gene_biotype: protein_coding
description:
  AMP-binding enzyme domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0571
symbol: EGV04993.1
gene_biotype: protein_coding
description:
  Glycosyltransferase, group 2 family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0572
symbol: EGV04974.1
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0574
symbol: EGV04992.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: HMPREF9952_0577
symbol: FabF_1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: HMPREF9952_0580
symbol: FabF_2
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: HMPREF9952_0582
symbol: rfaD
gene_biotype: protein_coding
description:
  ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: HMPREF9952_0583
symbol: cysZ
gene_biotype: protein_coding
description:
  Putative sulfate transport protein CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: HMPREF9952_0584
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: HMPREF9952_0585
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: HMPREF9952_0589
symbol: gcp
gene_biotype: protein_coding
description:
  Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: HMPREF9952_0591
symbol: DnaG
gene_biotype: protein_coding
description:
  DNA primase-like protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0592
symbol: EGV04788.1
gene_biotype: protein_coding
description:
  Putative DNA primase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0594
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: HMPREF9952_0595
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: HMPREF9952_0597
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: HMPREF9952_0598
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: HMPREF9952_0599
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: HMPREF9952_0600
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: HMPREF9952_0601
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: HMPREF9952_0602
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: HMPREF9952_0603
symbol: RplD
gene_biotype: protein_coding
description:
  Ribosomal protein, L4/L1-like family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0605
symbol: EGV04794.1
gene_biotype: protein_coding
description:
  Ribosomal protein L3-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0606
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: HMPREF9952_0607
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: HMPREF9952_0609
symbol: EGV04787.1
gene_biotype: protein_coding
description:
  Hemagglutinin/hemolysin family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0610
symbol: FhaB_1
gene_biotype: protein_coding
description:
  Hemagglutination activity domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0611
symbol: EGV05829.1
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin family N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0615
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: HMPREF9952_0619
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: HMPREF9952_0621
symbol: rarD
gene_biotype: protein_coding
description:
  Protein RarD; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: HMPREF9952_0626
symbol: tsaC
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: HMPREF9952_0627
symbol: EGV05775.1
gene_biotype: protein_coding
description:
  Putative shikimate dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0628
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0634
symbol: nanE
gene_biotype: protein_coding
description:
  ManNAc-6-P epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).


ensembl_gene_id: HMPREF9952_0637
symbol: nanA
gene_biotype: protein_coding
description:
  N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.


ensembl_gene_id: HMPREF9952_0638
symbol: NagB
gene_biotype: protein_coding
description:
  Putative glucosamine-6-phosphate deaminase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0639
symbol: EGV05689.1
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate isomerase/6-phosphogluconolactonase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0640
symbol: EGV05831.1
gene_biotype: protein_coding
description:
  Amidohydrolase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0641
symbol: nagA
gene_biotype: protein_coding
description:
  GlcNAc 6-P deacetylase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0642
symbol: HsrA
gene_biotype: protein_coding
description:
  Drug resistance MFS transporter, drug:H+ antiporter-2 family; Belongs to the major facilitator superfamily.


ensembl_gene_id: HMPREF9952_0647
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: HMPREF9952_0651
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: HMPREF9952_0652
symbol: fabR
gene_biotype: protein_coding
description:
  HTH-type transcriptional repressor FabR; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0653
symbol: oxyR
gene_biotype: protein_coding
description:
  Hydrogen peroxide-inducible protein activator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: HMPREF9952_0654
symbol: EGV05729.1
gene_biotype: protein_coding
description:
  Putative hybrid peroxiredoxin hyPrx5; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: HMPREF9952_0657
symbol: EGV05673.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0658
symbol: glpR
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate regulon repressor; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0660
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: HMPREF9952_0662
symbol: zapB
gene_biotype: protein_coding
description:
  Hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: HMPREF9952_0670
symbol: fkpB_2
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, FKBP-type; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0671
symbol: EGV05769.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, FKBP-type FkpA domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0674
symbol: ppx
gene_biotype: protein_coding
description:
  Exopolyphosphatase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the GppA/Ppx family.


ensembl_gene_id: HMPREF9952_0679
symbol: EGV05780.1
gene_biotype: protein_coding
description:
  Outer membrane protein, OMP85-like family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0680
symbol: EGV05736.1
gene_biotype: protein_coding
description:
  Outer membrane protein, OMP85 family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0682
symbol: RseA
gene_biotype: protein_coding
description:
  Putative sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cyto [...]


ensembl_gene_id: HMPREF9952_0685
symbol: FruA
gene_biotype: protein_coding
description:
  Phosphotransferase system, EIIC; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0687
symbol: LacC
gene_biotype: protein_coding
description:
  Putative 1-phosphofructokinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0689
symbol: EGV05670.1
gene_biotype: protein_coding
description:
  1-phosphofructokinase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0692
symbol: EGV05737.1
gene_biotype: protein_coding
description:
  Transporter associated domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0697
symbol: EGV05845.1
gene_biotype: protein_coding
description:
  Putative DNA polymerase III, delta' subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0698
symbol: holB
gene_biotype: protein_coding
description:
  DNA polymerase III, delta' subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0699
symbol: tmk
gene_biotype: protein_coding
description:
  dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: HMPREF9952_0700
symbol: mltG
gene_biotype: protein_coding
description:
  YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: HMPREF9952_0701
symbol: SurA
gene_biotype: protein_coding
description:
  PPIC-type PPIASE domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0702
symbol: EGV05768.1
gene_biotype: protein_coding
description:
  SurA N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0703
symbol: pyrR
gene_biotype: protein_coding
description:
  Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: HMPREF9952_0704
symbol: EGV05698.1
gene_biotype: protein_coding
description:
  Nucleic acid-binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0705
symbol: dnaE
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0706
symbol: gpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.


ensembl_gene_id: HMPREF9952_0739
symbol: EGV05656.1
gene_biotype: protein_coding
description:
  Mu-like prophage major head subunit gpT; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0740
symbol: EGV05661.1
gene_biotype: protein_coding
description:
  SAP domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0741
symbol: EGV05834.1
gene_biotype: protein_coding
description:
  Phage conserved hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0742
symbol: EGV05723.1
gene_biotype: protein_coding
description:
  Phage conserved hypothetical domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0745
symbol: EGV05681.1
gene_biotype: protein_coding
description:
  Phage tail sheath-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0746
symbol: EGV05792.1
gene_biotype: protein_coding
description:
  Putative phage tail sheath protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0749
symbol: EGV05790.1
gene_biotype: protein_coding
description:
  Tape measure domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0753
symbol: EGV05703.1
gene_biotype: protein_coding
description:
  Phage late control protein D protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_0754
symbol: EGV05841.1
gene_biotype: protein_coding
description:
  Phage late control protein D domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_0757
symbol: EGV05728.1
gene_biotype: protein_coding
description:
  Baseplate J-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0768
symbol: EGV05701.1
gene_biotype: protein_coding
description:
  Phage small terminase subunit-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0771
symbol: EGV05650.1
gene_biotype: protein_coding
description:
  Lysis protein S; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0783
symbol: EGV05724.1
gene_biotype: protein_coding
description:
  Phage-like baseplate assembly-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0795
symbol: EGV05806.1
gene_biotype: protein_coding
description:
  Phage tail protein, P2 GpE family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0814
symbol: EGV05680.1
gene_biotype: protein_coding
description:
  Bacteriophage replication protein A family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0817
symbol: EGV05710.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0826
symbol: EGV07630.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0831
symbol: EGV07651.1
gene_biotype: protein_coding
description:
  3'-5' exonuclease; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0832
symbol: rnd
gene_biotype: protein_coding
description:
  An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0833
symbol: EGV07617.1
gene_biotype: protein_coding
description:
  Methionine synthase, vitamin-B12 independent domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0834
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0835
symbol: EGV07661.1
gene_biotype: protein_coding
description:
  Putative phosphate acetyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0836
symbol: EGV07650.1
gene_biotype: protein_coding
description:
  Putative acetate kinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the acetokinase family.


ensembl_gene_id: HMPREF9952_0837
symbol: ackA
gene_biotype: protein_coding
description:
  Putative acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: HMPREF9952_0839
symbol: CvpA
gene_biotype: protein_coding
description:
  CvpA family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0840
symbol: EGV07601.1
gene_biotype: protein_coding
description:
  Putative colicin V production protein-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0841
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0843
symbol: EGV07646.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family 20, catalytic domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0845
symbol: metF
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate reductase (NAD(P)H); An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: HMPREF9952_0847
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: HMPREF9952_0853
symbol: EGV07620.1
gene_biotype: protein_coding
description:
  Putative IMP dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0854
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.


ensembl_gene_id: HMPREF9952_0858
symbol: EGV07675.1
gene_biotype: protein_coding
description:
  LPS glycosyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0871
symbol: EGV07628.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0875
symbol: CirA_2
gene_biotype: protein_coding
description:
  TonB-dependent receptor plug domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_0876
symbol: EGV07637.1
gene_biotype: protein_coding
description:
  TonB-dependent receptor; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_0879
symbol: BtuC
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HMPREF9952_0881
symbol: argS
gene_biotype: protein_coding
description:
  arginine--tRNA ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF9952_0882
symbol: EGV07674.1
gene_biotype: protein_coding
description:
  arginine--tRNA ligase, N-terminal domain; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0883
symbol: YecM
gene_biotype: protein_coding
description:
  YecM protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0887
symbol: KpsF
gene_biotype: protein_coding
description:
  Sugar isomerase, KpsF/GutQ family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0888
symbol: EGV07597.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: HMPREF9952_0891
symbol: EGV07652.1
gene_biotype: protein_coding
description:
  ABC transporter transmembrane region 2 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0894
symbol: EGV07629.1
gene_biotype: protein_coding
description:
  Ribose-phosphate diphosphokinase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0896
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: HMPREF9952_0897
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: HMPREF9952_0898
symbol: cca
gene_biotype: protein_coding
description:
  2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: HMPREF9952_0900
symbol: CysP
gene_biotype: protein_coding
description:
  Phosphate transporter family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0903
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: HMPREF9952_0906
symbol: ftsK
gene_biotype: protein_coding
description:
  DNA translocase FtsK; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: HMPREF9952_0910
symbol: NorM
gene_biotype: protein_coding
description:
  Multidrug efflux protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0911
symbol: ribE
gene_biotype: protein_coding
description:
  Riboflavin synthase, alpha subunit; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_0915
symbol: EGV05089.1
gene_biotype: protein_coding
description:
  Putative CRISPR-associated endonuclease Cas1, subtype II/NMENI; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0916
symbol: EGV05071.1
gene_biotype: protein_coding
description:
  CRISPR associated protein Cas1-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0919
symbol: cas9
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas9/Csn1, subtype II/NMEMI; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0921
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal L25p family protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: HMPREF9952_0924
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: HMPREF9952_0925
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: HMPREF9952_0931
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: HMPREF9952_0933
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: HMPREF9952_0934
symbol: GlgA
gene_biotype: protein_coding
description:
  Putative starch [bacterial glycogen] synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0936
symbol: glgP
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: HMPREF9952_0941
symbol: dinB
gene_biotype: protein_coding
description:
  ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: HMPREF9952_0942
symbol: EGV05048.1
gene_biotype: protein_coding
description:
  DNA polymerase IV domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0946
symbol: queF
gene_biotype: protein_coding
description:
  Queuine synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: HMPREF9952_0952
symbol: YohJ
gene_biotype: protein_coding
description:
  LrgA family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0957
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0960
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: HMPREF9952_0961
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: HMPREF9952_0964
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: HMPREF9952_0965
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: HMPREF9952_0966
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: HMPREF9952_0967
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: HMPREF9952_0971
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: HMPREF9952_0972
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: HMPREF9952_0973
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: HMPREF9952_0975
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: HMPREF9952_0985
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: HMPREF9952_0986
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: HMPREF9952_0987
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: HMPREF9952_0988
symbol: EGV05047.1
gene_biotype: protein_coding
description:
  Elongation factor Tu domain 2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0989
symbol: EGV05016.1
gene_biotype: protein_coding
description:
  Ribosome-binding factor A-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_0990
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: HMPREF9952_0991
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: HMPREF9952_0992
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: HMPREF9952_0996
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: HMPREF9952_0997
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: HMPREF9952_0998
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: HMPREF9952_1000
symbol: EGV05360.1
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1001
symbol: PyrD
gene_biotype: protein_coding
description:
  Putative dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: HMPREF9952_1004
symbol: EGV05369.1
gene_biotype: protein_coding
description:
  Toprim domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1005
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: HMPREF9952_1007
symbol: EGV05370.1
gene_biotype: protein_coding
description:
  Nickel uptake substrate-specific transmembrane region domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1010
symbol: Fnr
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1015
symbol: EGV05350.1
gene_biotype: protein_coding
description:
  Exonuclease C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1018
symbol: EGV05354.1
gene_biotype: protein_coding
description:
  Hypothetical protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1019
symbol: mukB
gene_biotype: protein_coding
description:
  Chromosome partition protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.


ensembl_gene_id: HMPREF9952_1020
symbol: mukE
gene_biotype: protein_coding
description:
  Chromosome partition protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.


ensembl_gene_id: HMPREF9952_1021
symbol: mukF
gene_biotype: protein_coding
description:
  Chromosome partition protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.


ensembl_gene_id: HMPREF9952_1023
symbol: ttcA
gene_biotype: protein_coding
description:
  PP-loop family protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: HMPREF9952_1028
symbol: EGV04844.1
gene_biotype: protein_coding
description:
  Formylglycine-generating sulfatase enzyme; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1035
symbol: EGV04802.1
gene_biotype: protein_coding
description:
  Bacterial virulence factor domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1049
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: HMPREF9952_1050
symbol: RecB
gene_biotype: protein_coding
description:
  UvrD/REP helicase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1051
symbol: EGV04853.1
gene_biotype: protein_coding
description:
  UvrD/REP helicase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: HMPREF9952_1052
symbol: EGV04825.1
gene_biotype: protein_coding
description:
  Type I restriction-modification system, M subunit-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1054
symbol: EGV04799.1
gene_biotype: protein_coding
description:
  Type I restriction modification DNA specificity domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1058
symbol: HsdR2
gene_biotype: protein_coding
description:
  Type I restriction enzyme R protein, N-terminal domain protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: HMPREF9952_1060
symbol: EGV04869.1
gene_biotype: protein_coding
description:
  Type I restriction and modification enzyme - subunit R C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1065
symbol: YbaK_2
gene_biotype: protein_coding
description:
  YbaK/proline--tRNA ligase associated domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1067
symbol: fabA
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: HMPREF9952_1068
symbol: EGV04843.1
gene_biotype: protein_coding
description:
  Lon protease S16 C-terminal proteolytic domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1070
symbol: matP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.


ensembl_gene_id: HMPREF9952_1073
symbol: TruC
gene_biotype: protein_coding
description:
  RNA pseudouridine synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1078
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: HMPREF9952_1079
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: HMPREF9952_1080
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: HMPREF9952_1084
symbol: EGV04888.1
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfD domain protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: HMPREF9952_1085
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: HMPREF9952_1086
symbol: EGV04839.1
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfG; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1087
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: HMPREF9952_1088
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: HMPREF9952_1089
symbol: EGV04841.1
gene_biotype: protein_coding
description:
  Sodium:neurotransmitter symporter domain protein; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: HMPREF9952_1091
symbol: thrS
gene_biotype: protein_coding
description:
  threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: HMPREF9952_1092
symbol: azoR
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: HMPREF9952_1096
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: HMPREF9952_1099
symbol: EGV04830.1
gene_biotype: protein_coding
description:
  Hydrogenase-2 operon protein HybA family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1100
symbol: FdoH_2
gene_biotype: protein_coding
description:
  Putative Hydrogenase-2 operon protein HybA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1106
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: HMPREF9952_1107
symbol: purR
gene_biotype: protein_coding
description:
  HTH-type transcriptional repressor PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.


ensembl_gene_id: HMPREF9952_1108
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: HMPREF9952_1124
symbol: prmB
gene_biotype: protein_coding
description:
  (glutamine-N5) methyltransferase, ribosomal protein L3-specific; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: HMPREF9952_1125
symbol: GpmA_2
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1126
symbol: CusC
gene_biotype: protein_coding
description:
  Efflux transporter, outer membrane factor lipoprotein, NodT family; Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.


ensembl_gene_id: HMPREF9952_1127
symbol: macB
gene_biotype: protein_coding
description:
  Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: HMPREF9952_1132
symbol: EGV07771.1
gene_biotype: protein_coding
description:
  Putative isocitrate dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1133
symbol: icd
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1134
symbol: acnB
gene_biotype: protein_coding
description:
  Aconitate hydratase 2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: HMPREF9952_1140
symbol: EGV07728.1
gene_biotype: protein_coding
description:
  Fructosamine kinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the fructosamine kinase family.


ensembl_gene_id: HMPREF9952_1142
symbol: SohB
gene_biotype: protein_coding
description:
  Peptidase, S49 protease IV family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1143
symbol: EGV07766.1
gene_biotype: protein_coding
description:
  Peptidase family S49 N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1146
symbol: asnS
gene_biotype: protein_coding
description:
  asparagine--tRNA ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1147
symbol: can
gene_biotype: protein_coding
description:
  Carbonic anhydrase 2; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: HMPREF9952_1148
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: HMPREF9952_1151
symbol: sixA
gene_biotype: protein_coding
description:
  Phosphohistidine phosphatase SixA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1152
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: HMPREF9952_1153
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: HMPREF9952_1154
symbol: MinD
gene_biotype: protein_coding
description:
  ParA/MinD ATPase-like protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: HMPREF9952_1155
symbol: EGV07709.1
gene_biotype: protein_coding
description:
  methionine--tRNA ligase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF9952_1156
symbol: metG
gene_biotype: protein_coding
description:
  methionine--tRNA ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1157
symbol: EGV07769.1
gene_biotype: protein_coding
description:
  Putative methionine--tRNA ligase, beta subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1159
symbol: tehB
gene_biotype: protein_coding
description:
  Tellurite resistance protein TehB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1161
symbol: YxaB
gene_biotype: protein_coding
description:
  Polysaccharide pyruvyl transferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1163
symbol: EGV07768.1
gene_biotype: protein_coding
description:
  Nitroreductase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1164
symbol: EGV07743.1
gene_biotype: protein_coding
description:
  TIGR01619 family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1168
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: HMPREF9952_1169
symbol: sucA
gene_biotype: protein_coding
description:
  Oxoglutarate dehydrogenase (succinyl-transferring), E1 component; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1175
symbol: EGV07741.1
gene_biotype: protein_coding
description:
  L,D-transpeptidase catalytic domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1177
symbol: proQ
gene_biotype: protein_coding
description:
  ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.


ensembl_gene_id: HMPREF9952_1181
symbol: EGV07710.1
gene_biotype: protein_coding
description:
  ATP cone domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1182
symbol: NrdA
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: HMPREF9952_1187
symbol: MoeA
gene_biotype: protein_coding
description:
  MoeA N-terminal region (domain I and II); Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: HMPREF9952_1194
symbol: fdhE
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: HMPREF9952_1195
symbol: rimI
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: HMPREF9952_1196
symbol: HolD
gene_biotype: protein_coding
description:
  Putative DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.


ensembl_gene_id: HMPREF9952_1199
symbol: rsmC
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: HMPREF9952_1201
symbol: EGV07755.1
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase, membrane binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1202
symbol: ldhA_2
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1204
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: HMPREF9952_1209
symbol: EGV05328.1
gene_biotype: protein_coding
description:
  TIR domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1210
symbol: metH
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: HMPREF9952_1212
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: HMPREF9952_1213
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: HMPREF9952_1214
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: HMPREF9952_1215
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1217
symbol: valS
gene_biotype: protein_coding
description:
  valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: HMPREF9952_1223
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: HMPREF9952_1226
symbol: grxA
gene_biotype: protein_coding
description:
  Glutaredoxin, GrxA family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1227
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: HMPREF9952_1230
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: HMPREF9952_1231
symbol: hflB
gene_biotype: protein_coding
description:
  Cell division protease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: HMPREF9952_1232
symbol: rrmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: HMPREF9952_1234
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: HMPREF9952_1235
symbol: DacB
gene_biotype: protein_coding
description:
  Putative D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1236
symbol: EGV05327.1
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1237
symbol: dmsD
gene_biotype: protein_coding
description:
  Nitrate reductase delta subunit; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein.


ensembl_gene_id: HMPREF9952_1241
symbol: EGV05284.1
gene_biotype: protein_coding
description:
  TonB-dependent receptor plug domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1242
symbol: FhuA
gene_biotype: protein_coding
description:
  Putative TonB-dependent outer membrane ferric coprogen receptor FitA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1244
symbol: rluB
gene_biotype: protein_coding
description:
  Pseudouridine synthase B, ribosomal large subunit; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: HMPREF9952_1245
symbol: EGV05296.1
gene_biotype: protein_coding
description:
  YrdC domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1246
symbol: YciO
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC-like family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the SUA5 family.


ensembl_gene_id: HMPREF9952_1247
symbol: EGV05338.1
gene_biotype: protein_coding
description:
  Putative succinyl-CoA synthetase, alpha subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1249
symbol: sucC
gene_biotype: protein_coding
description:
  succinate-CoA ligase, beta subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1251
symbol: clsA
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: HMPREF9952_1254
symbol: dmsA
gene_biotype: protein_coding
description:
  Anaerobic dimethyl sulfoxide reductase chain A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HMPREF9952_1255
symbol: DmsA_2
gene_biotype: protein_coding
description:
  Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HMPREF9952_1256
symbol: DmsA_3
gene_biotype: protein_coding
description:
  Tat pathway signal sequence domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_1260
symbol: sodC
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: HMPREF9952_1261
symbol: SodC
gene_biotype: protein_coding
description:
  Copper/zinc superoxide dismutase-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1263
symbol: HbpA_2
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1264
symbol: EGV05314.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 5 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1269
symbol: EGV05309.1
gene_biotype: protein_coding
description:
  Sodium Bile acid symporter family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1275
symbol: EGV05305.1
gene_biotype: protein_coding
description:
  Peptidase, S49 protease IV domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1276
symbol: sppA
gene_biotype: protein_coding
description:
  Signal peptide peptidase SppA, 67K type; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1278
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: HMPREF9952_1279
symbol: EGV05346.1
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase Fe4S4 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_1280
symbol: EGV05322.1
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase, nitrate-inducible, major subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_1281
symbol: EGV05308.1
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase, nitrate-inducible, major subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1282
symbol: fdxH
gene_biotype: protein_coding
description:
  Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: HMPREF9952_1284
symbol: Spr_2
gene_biotype: protein_coding
description:
  NlpC/P60 family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1285
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: HMPREF9952_1286
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: HMPREF9952_1287
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: HMPREF9952_1288
symbol: Gcr
gene_biotype: protein_coding
description:
  Site-specific recombinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1290
symbol: fbpC
gene_biotype: protein_coding
description:
  TOBE domain protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HMPREF9952_1291
symbol: AfuB
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1299
symbol: sotB
gene_biotype: protein_coding
description:
  Sugar efflux transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: HMPREF9952_1300
symbol: agcS_1
gene_biotype: protein_coding
description:
  Amino acid carrier protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1301
symbol: glk
gene_biotype: protein_coding
description:
  Glucokinase; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.


ensembl_gene_id: HMPREF9952_1302
symbol: EGV05908.1
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the UPF0263 family.


ensembl_gene_id: HMPREF9952_1304
symbol: AroG
gene_biotype: protein_coding
description:
  3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: HMPREF9952_1308
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein ABC transporter, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: HMPREF9952_1309
symbol: LolC
gene_biotype: protein_coding
description:
  Lipoprotein releasing system, transmembrane protein, LolC/E family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1310
symbol: pdxB
gene_biotype: protein_coding
description:
  4-phosphoerythronate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HMPREF9952_1313
symbol: prmC
gene_biotype: protein_coding
description:
  protein-(glutamine-N5) methyltransferase, release factor-specific; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1316
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: HMPREF9952_1318
symbol: pntB
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: HMPREF9952_1319
symbol: pntA
gene_biotype: protein_coding
description:
  NAD(P)(+) transhydrogenase (AB-specific), alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.


ensembl_gene_id: HMPREF9952_1321
symbol: rsmI
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: HMPREF9952_1322
symbol: lpoA
gene_biotype: protein_coding
description:
  LppC putative lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.


ensembl_gene_id: HMPREF9952_1331
symbol: mnmC
gene_biotype: protein_coding
description:
  5-methylaminomethyl-2-thiouridine methyltransferase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: HMPREF9952_1333
symbol: EGV05874.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide export system permease protein LptG domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1334
symbol: LptG
gene_biotype: protein_coding
description:
  Permease, YjgP/YjgQ family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1336
symbol: pepA
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase family, catalytic domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: HMPREF9952_1339
symbol: ric
gene_biotype: protein_coding
description:
  Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: HMPREF9952_1341
symbol: EGV05945.1
gene_biotype: protein_coding
description:
  Phosphate acetyl/butyryl transferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1342
symbol: MaeB
gene_biotype: protein_coding
description:
  Putative malate dehydrogenase (oxaloacetate-decarboxylating); An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1350
symbol: EGV05907.1
gene_biotype: protein_coding
description:
  Putative oligopeptide ABC transporter, ATP-binding protein OppD; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1351
symbol: oppD
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter, ATP-binding protein OppD; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1352
symbol: GsiA_6
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide transporter, C-terminal domain protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HMPREF9952_1366
symbol: EGV05236.1
gene_biotype: protein_coding
description:
  Putative hemagglutinin DUF638; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1369
symbol: FhaB_2
gene_biotype: protein_coding
description:
  Filamentous hemagglutinin family N-terminal domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1372
symbol: EGV05106.1
gene_biotype: protein_coding
description:
  Conserved domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_1381
symbol: EGV05151.1
gene_biotype: protein_coding
description:
  Hemolysin secretion/activation protein, ShlB/FhaC/HecB family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1382
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: HMPREF9952_1383
symbol: potA
gene_biotype: protein_coding
description:
  Putrescine/spermidine ABC transporter ATPase protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: HMPREF9952_1389
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF9952_1390
symbol: RbsK
gene_biotype: protein_coding
description:
  Putative fructokinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1391
symbol: scrK
gene_biotype: protein_coding
description:
  Fructokinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1393
symbol: ScrB
gene_biotype: protein_coding
description:
  Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: HMPREF9952_1398
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: HMPREF9952_1400
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: HMPREF9952_1403
symbol: EGV05142.1
gene_biotype: protein_coding
description:
  YcaO-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1404
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: HMPREF9952_1405
symbol: MioC_2
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) flavoprotein, alpha component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: HMPREF9952_1406
symbol: EGV05131.1
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] flavoprotein alpha-component domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1407
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: HMPREF9952_1409
symbol: cysH
gene_biotype: protein_coding
description:
  Adenylylsulfate reductase, thioredoxin dependent; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: HMPREF9952_1410
symbol: cobA
gene_biotype: protein_coding
description:
  uroporphyrinogen-III C-methyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: HMPREF9952_1411
symbol: EGV05110.1
gene_biotype: protein_coding
description:
  Siroheme synthase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1413
symbol: cysT
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: HMPREF9952_1415
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HMPREF9952_1417
symbol: modC
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: HMPREF9952_1418
symbol: modB
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: HMPREF9952_1419
symbol: modA
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, periplasmic molybdate-binding protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1421
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: HMPREF9952_1423
symbol: ParC
gene_biotype: protein_coding
description:
  Putative DNA topoisomerase IV, A subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1424
symbol: EGV05209.1
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1425
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: HMPREF9952_1427
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: HMPREF9952_1430
symbol: crr
gene_biotype: protein_coding
description:
  Glucose-specific phosphotransferase enzyme IIA component; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1431
symbol: ptsP
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: HMPREF9952_1433
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: HMPREF9952_1434
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: HMPREF9952_1438
symbol: EGV05173.1
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1439
symbol: AmiB
gene_biotype: protein_coding
description:
  LysM domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_1440
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: HMPREF9952_1441
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: HMPREF9952_1442
symbol: GlnE
gene_biotype: protein_coding
description:
  GlnD PII-uridylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein P [...]


ensembl_gene_id: HMPREF9952_1445
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: HMPREF9952_1446
symbol: hfq
gene_biotype: protein_coding
description:
  RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: HMPREF9952_1447
symbol: rluC
gene_biotype: protein_coding
description:
  rRNA pseudouridylate synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: HMPREF9952_1448
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E RNase E (first module); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: HMPREF9952_1452
symbol: FecD_3
gene_biotype: protein_coding
description:
  Iron chelate uptake ABC transporter, FeCT family, permease domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HMPREF9952_1455
symbol: EGV05223.1
gene_biotype: protein_coding
description:
  Peptidase, M23 family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1457
symbol: znuC
gene_biotype: protein_coding
description:
  High-affinity zinc transporter ATPase; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: HMPREF9952_1459
symbol: EGV05105.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1460
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: HMPREF9952_1461
symbol: PdxY
gene_biotype: protein_coding
description:
  Pyridoxal kinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the pyridoxine kinase family.


ensembl_gene_id: HMPREF9952_1462
symbol: EGV05130.1
gene_biotype: protein_coding
description:
  Pyridoxal kinase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1463
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: HMPREF9952_1467
symbol: mltA
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: HMPREF9952_1470
symbol: EGV05187.1
gene_biotype: protein_coding
description:
  HflC-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1474
symbol: ThrC
gene_biotype: protein_coding
description:
  Putative threonine synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1476
symbol: ThrB
gene_biotype: protein_coding
description:
  Putative homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: HMPREF9952_1477
symbol: EGV05119.1
gene_biotype: protein_coding
description:
  Homoserine kinase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1478
symbol: ThrA
gene_biotype: protein_coding
description:
  Homoserine dehydrogenase; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: HMPREF9952_1479
symbol: EGV05147.1
gene_biotype: protein_coding
description:
  Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: HMPREF9952_1482
symbol: EGV05178.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: HMPREF9952_1483
symbol: secF
gene_biotype: protein_coding
description:
  Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: HMPREF9952_1484
symbol: secD
gene_biotype: protein_coding
description:
  Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: HMPREF9952_1486
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: HMPREF9952_1487
symbol: EGV05138.1
gene_biotype: protein_coding
description:
  Preprotein translocase, YajC subunit-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1491
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]


ensembl_gene_id: HMPREF9952_1493
symbol: EGV05163.1
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase domain protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: HMPREF9952_1494
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: HMPREF9952_1495
symbol: EGV05104.1
gene_biotype: protein_coding
description:
  Putative S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: HMPREF9952_1497
symbol: plsB
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate O-acyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the GPAT/DAPAT family.


ensembl_gene_id: HMPREF9952_1498
symbol: lexA
gene_biotype: protein_coding
description:
  Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: HMPREF9952_1499
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: HMPREF9952_1501
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: HMPREF9952_1505
symbol: LeuA
gene_biotype: protein_coding
description:
  Putative 2-isopropylmalate synthase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: HMPREF9952_1507
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: HMPREF9952_1509
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: HMPREF9952_1510
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: HMPREF9952_1512
symbol: ybeY
gene_biotype: protein_coding
description:
  Metalloprotein, YbeY family; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: HMPREF9952_1522
symbol: wecA
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). Belongs to the glycosyltransferase 4 family. WecA subfamily.


ensembl_gene_id: HMPREF9952_1524
symbol: EGV05954.1
gene_biotype: protein_coding
description:
  ACT domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1525
symbol: EGV06624.1
gene_biotype: protein_coding
description:
  Conserved domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1526
symbol: glnD
gene_biotype: protein_coding
description:
  HD domain protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: HMPREF9952_1527
symbol: glnD-2
gene_biotype: protein_coding
description:
  GlnD PII-uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: HMPREF9952_1528
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: HMPREF9952_1529
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: HMPREF9952_1531
symbol: MrcB
gene_biotype: protein_coding
description:
  Putative penicillin-binding protein 1B; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1532
symbol: EGV06620.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1534
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1535
symbol: EGV06656.1
gene_biotype: protein_coding
description:
  Excinuclease ABC, C subunit-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1536
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: HMPREF9952_1537
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: HMPREF9952_1538
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: HMPREF9952_1539
symbol: EGV06623.1
gene_biotype: protein_coding
description:
  DNA internalization competence protein ComEC/Rec2-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1543
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1544
symbol: pcnB
gene_biotype: protein_coding
description:
  Polynucleotide adenylyltransferase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: HMPREF9952_1546
symbol: FolK
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1547
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: HMPREF9952_1550
symbol: purA-2
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase-like protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: HMPREF9952_1551
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: HMPREF9952_1557
symbol: EGV06636.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent helicase HrpA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1560
symbol: KefC
gene_biotype: protein_coding
description:
  Transporter, CPA2 family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: HMPREF9952_1563
symbol: nadK
gene_biotype: protein_coding
description:
  NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: HMPREF9952_1564
symbol: grpE
gene_biotype: protein_coding
description:
  Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]


ensembl_gene_id: HMPREF9952_1567
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]


ensembl_gene_id: HMPREF9952_1573
symbol: EGV06202.1
gene_biotype: protein_coding
description:
  Invasion protein expression up-regulator SirB; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1574
symbol: EGV04905.1
gene_biotype: protein_coding
description:
  Translation initiation factor Sui1 domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1575
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: HMPREF9952_1578
symbol: lapA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: HMPREF9952_1579
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: HMPREF9952_1580
symbol: EGV04909.1
gene_biotype: protein_coding
description:
  Putative 30S ribosomal protein S1; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1585
symbol: mtnN
gene_biotype: protein_coding
description:
  MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: HMPREF9952_1586
symbol: DsbA_2
gene_biotype: protein_coding
description:
  DSBA-like thioredoxin domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1588
symbol: DsbC
gene_biotype: protein_coding
description:
  Disulfide bond isomerase protein N-terminal domain protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: HMPREF9952_1589
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: HMPREF9952_1590
symbol: lysS
gene_biotype: protein_coding
description:
  lysine--tRNA ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: HMPREF9952_1591
symbol: GsiA_2
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide transporter, C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the ABC transporter superfamily.


ensembl_gene_id: HMPREF9952_1597
symbol: serS
gene_biotype: protein_coding
description:
  serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: HMPREF9952_1600
symbol: EGV05242.1
gene_biotype: protein_coding
description:
  EamA-like transporter family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1603
symbol: ProA
gene_biotype: protein_coding
description:
  Putative glutamate-5-semialdehyde dehydrogenase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: HMPREF9952_1604
symbol: EGV05263.1
gene_biotype: protein_coding
description:
  Putative gamma-glutamyl phosphate reductase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1606
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: HMPREF9952_1607
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: HMPREF9952_1611
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: HMPREF9952_1618
symbol: EGV05265.1
gene_biotype: protein_coding
description:
  Methyltransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the methyltransferase superfamily.


ensembl_gene_id: HMPREF9952_1619
symbol: RlmL
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: HMPREF9952_1620
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: HMPREF9952_1621
symbol: Dat1
gene_biotype: protein_coding
description:
  methylated-DNA--[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: HMPREF9952_1623
symbol: PhnA_1
gene_biotype: protein_coding
description:
  Putative alkylphosphonate utilization operon protein PhnA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1624
symbol: YtfJ_1
gene_biotype: protein_coding
description:
  TIGR01626 family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1626
symbol: RpoE_2
gene_biotype: protein_coding
description:
  Sigma-70, region 4; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1630
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1631
symbol: OmpW
gene_biotype: protein_coding
description:
  OmpW family protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_1633
symbol: EGV07696.1
gene_biotype: protein_coding
description:
  Intracellular septation protein A-like protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: HMPREF9952_1634
symbol: YciB
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: HMPREF9952_1638
symbol: Slt
gene_biotype: protein_coding
description:
  Transglycosylase SLT domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1639
symbol: trpR
gene_biotype: protein_coding
description:
  Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.


ensembl_gene_id: HMPREF9952_1640
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: HMPREF9952_1641
symbol: EGV07689.1
gene_biotype: protein_coding
description:
  DNA gyrase, A subunit domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1642
symbol: EGV07685.1
gene_biotype: protein_coding
description:
  DNA gyrase/topoisomerase IV, A subunit domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1643
symbol: GyrA
gene_biotype: protein_coding
description:
  Putative DNA gyrase, A subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1649
symbol: SstT
gene_biotype: protein_coding
description:
  Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: HMPREF9952_1650
symbol: EGV07680.1
gene_biotype: protein_coding
description:
  Serine/threonine transporter SstT domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1654
symbol: EGV06354.1
gene_biotype: protein_coding
description:
  2-oxoacid dehydrogenase acyltransferase, catalytic domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1655
symbol: aceF
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1656
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: HMPREF9952_1659
symbol: EGV06403.1
gene_biotype: protein_coding
description:
  O-acetylhomoserine aminocarboxypropyltransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1660
symbol: EGV06387.1
gene_biotype: protein_coding
description:
  Putative O-acetylhomoserine aminocarboxypropyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1661
symbol: MetB
gene_biotype: protein_coding
description:
  O-acetylhomoserine aminocarboxypropyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1662
symbol: EGV06334.1
gene_biotype: protein_coding
description:
  Cys/Met metabolism PLP-dependent enzyme domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1663
symbol: DnaJ
gene_biotype: protein_coding
description:
  DnaJ C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1665
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: HMPREF9952_1667
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: HMPREF9952_1670
symbol: rnb
gene_biotype: protein_coding
description:
  Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: HMPREF9952_1672
symbol: EGV06379.1
gene_biotype: protein_coding
description:
  Endonuclease/exonuclease/phosphatase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1673
symbol: GlgP
gene_biotype: protein_coding
description:
  Phosphorylase, glycogen/starch/alpha-glucan family; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: HMPREF9952_1674
symbol: MalQ_1
gene_biotype: protein_coding
description:
  4-alpha-glucanotransferase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1677
symbol: TreR
gene_biotype: protein_coding
description:
  UbiC transcription regulator-associated domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1678
symbol: PutA
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: HMPREF9952_1679
symbol: putP
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: HMPREF9952_1683
symbol: ilvB_1
gene_biotype: protein_coding
description:
  Acetolactate synthase, large subunit, biosynthetic type; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1689
symbol: EGV06325.1
gene_biotype: protein_coding
description:
  Type I restriction enzyme R protein, N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1691
symbol: HsdR
gene_biotype: protein_coding
description:
  Type III restriction enzyme, res subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: HMPREF9952_1695
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: HMPREF9952_1696
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: HMPREF9952_1697
symbol: thiQ
gene_biotype: protein_coding
description:
  Thiamine ABC transporter, ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.


ensembl_gene_id: HMPREF9952_1698
symbol: thiP
gene_biotype: protein_coding
description:
  Thiamine transporter membrane protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1699
symbol: EGV06333.1
gene_biotype: protein_coding
description:
  Thiamine transporter membrane domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1707
symbol: EGV06380.1
gene_biotype: protein_coding
description:
  FAD linked oxidase, C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1709
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: HMPREF9952_1713
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: HMPREF9952_1715
symbol: engA
gene_biotype: protein_coding
description:
  Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: HMPREF9952_1716
symbol: EGV06358.1
gene_biotype: protein_coding
description:
  MreB/Mbl domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1717
symbol: DnaK_1
gene_biotype: protein_coding
description:
  Putative cell division protein FtsA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1720
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: HMPREF9952_1723
symbol: lptC
gene_biotype: protein_coding
description:
  Putative lipopolysaccharide export system protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.


ensembl_gene_id: HMPREF9952_1724
symbol: lptA
gene_biotype: protein_coding
description:
  Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: HMPREF9952_1725
symbol: LptB
gene_biotype: protein_coding
description:
  Putative lipopolysaccharide ABC transporter, ATP-binding protein LptB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1726
symbol: EGV06404.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1729
symbol: EGV06342.1
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1730
symbol: EGV06317.1
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1732
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: HMPREF9952_1737
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: HMPREF9952_1741
symbol: ggt
gene_biotype: protein_coding
description:
  Gamma-glutamyltranspeptidase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1742
symbol: EGV06398.1
gene_biotype: protein_coding
description:
  Putative gamma-glutamyltranspeptidase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1747
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: HMPREF9952_1748
symbol: menH
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: HMPREF9952_1749
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: HMPREF9952_1751
symbol: EGV06382.1
gene_biotype: protein_coding
description:
  Putative aminotransferase AlaT; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1752
symbol: EGV06364.1
gene_biotype: protein_coding
description:
  Aminotransferase AlaT; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1760
symbol: EGV06031.1
gene_biotype: protein_coding
description:
  ABC transporter, solute-binding protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1766
symbol: PotA_1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1767
symbol: EGV06121.1
gene_biotype: protein_coding
description:
  Putative putrescine/spermidine ABC transporter ATPase protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1768
symbol: Sxy
gene_biotype: protein_coding
description:
  TfoX C-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1769
symbol: EGV05976.1
gene_biotype: protein_coding
description:
  TfoX N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1774
symbol: EGV05956.1
gene_biotype: protein_coding
description:
  ABC-2 type transporter domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1776
symbol: FabF_3
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase, C-terminal domain protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: HMPREF9952_1777
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: HMPREF9952_1779
symbol: EGV05979.1
gene_biotype: protein_coding
description:
  Transposase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_1783
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: HMPREF9952_1784
symbol: EGV05999.1
gene_biotype: protein_coding
description:
  Putative ATP synthase F0, I subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1785
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: HMPREF9952_1786
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HMPREF9952_1787
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: HMPREF9952_1788
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: HMPREF9952_1789
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: HMPREF9952_1790
symbol: EGV06130.1
gene_biotype: protein_coding
description:
  ATP synthase F1, gamma subunit-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1791
symbol: atpG
gene_biotype: protein_coding
description:
  F-ATPase gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: HMPREF9952_1792
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: HMPREF9952_1793
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: HMPREF9952_1795
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: HMPREF9952_1796
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: HMPREF9952_1797
symbol: EGV06041.1
gene_biotype: protein_coding
description:
  Rhodanese domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1798
symbol: YibN
gene_biotype: protein_coding
description:
  Rhodanese-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1801
symbol: EGV06107.1
gene_biotype: protein_coding
description:
  ABC transporter transmembrane region domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1803
symbol: HgpA_1
gene_biotype: protein_coding
description:
  Putative hemoglobin and hemoglobin-haptoglobin-binding protein A; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1804
symbol: udp
gene_biotype: protein_coding
description:
  Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: HMPREF9952_1809
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: HMPREF9952_1815
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: HMPREF9952_1817
symbol: crcB
gene_biotype: protein_coding
description:
  Protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: HMPREF9952_1818
symbol: EGV06174.1
gene_biotype: protein_coding
description:
  Putative regulatory protein RecX; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1820
symbol: recA
gene_biotype: protein_coding
description:
  RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: HMPREF9952_1822
symbol: EGV06139.1
gene_biotype: protein_coding
description:
  Phospholipase, patatin family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1826
symbol: EGV06124.1
gene_biotype: protein_coding
description:
  Putative C-terminal regulatory domain of Threonine dehydratase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1827
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine ammonia-lyase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: HMPREF9952_1832
symbol: EGV06069.1
gene_biotype: protein_coding
description:
  Sodium:neurotransmitter symporter family protein; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: HMPREF9952_1837
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: HMPREF9952_1838
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: HMPREF9952_1840
symbol: asd_2
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: HMPREF9952_1842
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: HMPREF9952_1844
symbol: EGV06133.1
gene_biotype: protein_coding
description:
  IgA-specific serine endopeptidase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1845
symbol: RecF_2
gene_biotype: protein_coding
description:
  Pertactin; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1846
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, B subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1847
symbol: EGV06180.1
gene_biotype: protein_coding
description:
  ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1848
symbol: YqaB
gene_biotype: protein_coding
description:
  Haloacid dehalogenase-like hydrolase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1849
symbol: EGV06002.1
gene_biotype: protein_coding
description:
  HAD hydrolase, family IA, variant 3 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1851
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: HMPREF9952_1852
symbol: EGV06019.1
gene_biotype: protein_coding
description:
  Putative phosphoribosylglycinamide formyltransferase 2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1853
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1854
symbol: PdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase-like protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: HMPREF9952_1855
symbol: EGV06145.1
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1857
symbol: dcuA
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter DcuA; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: HMPREF9952_1859
symbol: CpdB
gene_biotype: protein_coding
description:
  2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: HMPREF9952_1860
symbol: EGV05995.1
gene_biotype: protein_coding
description:
  An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: HMPREF9952_1861
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: HMPREF9952_1863
symbol: EGV06013.1
gene_biotype: protein_coding
description:
  TonB-dependent receptor domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1867
symbol: hslO
gene_biotype: protein_coding
description:
  Chaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: HMPREF9952_1869
symbol: OmpH_1
gene_biotype: protein_coding
description:
  Gram-negative porin; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1874
symbol: MrcA
gene_biotype: protein_coding
description:
  Putative penicillin-binding protein 1A; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1875
symbol: EGV06016.1
gene_biotype: protein_coding
description:
  Transglycosylase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1880
symbol: EGV06068.1
gene_biotype: protein_coding
description:
  Bacterial type II/III secretion system short domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1881
symbol: PilQ
gene_biotype: protein_coding
description:
  Bacterial type II and III secretion system protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the bacterial secretin family.


ensembl_gene_id: HMPREF9952_1883
symbol: yhgI
gene_biotype: protein_coding
description:
  IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: HMPREF9952_1884
symbol: hypF
gene_biotype: protein_coding
description:
  Carbamoyltransferase HypF; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1885
symbol: EGV05985.1
gene_biotype: protein_coding
description:
  Putative acylphosphatase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1887
symbol: EGV06062.1
gene_biotype: protein_coding
description:
  Hydrogenase 4 subunit B domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_1888
symbol: HyfB_1
gene_biotype: protein_coding
description:
  Hydrogenase 4 subunit B; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_1900
symbol: FdhF
gene_biotype: protein_coding
description:
  Formate dehydrogenase, alpha subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: HMPREF9952_1903
symbol: ysxC
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: HMPREF9952_1905
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, large subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the CarB family.


ensembl_gene_id: HMPREF9952_1906
symbol: EGV06024.1
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase L chain, N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1908
symbol: EGV06027.1
gene_biotype: protein_coding
description:
  Carbamoyl phosphate synthase small subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1909
symbol: CarA
gene_biotype: protein_coding
description:
  Putative carbamoyl phosphate synthase small subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1912
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: HMPREF9952_1913
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: HMPREF9952_1914
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF9952_1915
symbol: EGV06017.1
gene_biotype: protein_coding
description:
  RNA polymerase Rpb1, domain 1; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1916
symbol: rpoC
gene_biotype: protein_coding
description:
  Transcriptase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF9952_1917
symbol: EGV05991.1
gene_biotype: protein_coding
description:
  RNA polymerase Rpb1, domain 5 protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1918
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: HMPREF9952_1921
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: HMPREF9952_1922
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24-like protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: HMPREF9952_1923
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: HMPREF9952_1924
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: HMPREF9952_1925
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: HMPREF9952_1926
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: HMPREF9952_1927
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: HMPREF9952_1928
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: HMPREF9952_1930
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: HMPREF9952_1931
symbol: EGV06074.1
gene_biotype: protein_coding
description:
  Putative preprotein translocase, SecY subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the SecY/SEC61-alpha family.


ensembl_gene_id: HMPREF9952_1932
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: HMPREF9952_1935
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: HMPREF9952_1936
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: HMPREF9952_1937
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: HMPREF9952_1938
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: HMPREF9952_1940
symbol: Gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1943
symbol: AphA_2
gene_biotype: protein_coding
description:
  HAD phosphatase, family IIIB-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1944
symbol: EGV06118.1
gene_biotype: protein_coding
description:
  Putative class B acid phosphatase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1946
symbol: HgpA_2
gene_biotype: protein_coding
description:
  TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1948
symbol: gnd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: HMPREF9952_1957
symbol: EGV06032.1
gene_biotype: protein_coding
description:
  Transporter, major facilitator domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1960
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: HMPREF9952_1961
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: HMPREF9952_1964
symbol: HslR
gene_biotype: protein_coding
description:
  S4 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1966
symbol: EGV05990.1
gene_biotype: protein_coding
description:
  TIGR00645 family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_1967
symbol: RmuC
gene_biotype: protein_coding
description:
  RmuC domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1970
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease HslVU, peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: HMPREF9952_1972
symbol: HslU
gene_biotype: protein_coding
description:
  ATP-dependent protease HslVU, ATPase subunit-like protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.


ensembl_gene_id: HMPREF9952_1973
symbol: EGV05962.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent hsl protease ATP-binding subunit HslU; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1975
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: HMPREF9952_1976
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: HMPREF9952_1983
symbol: hcr
gene_biotype: protein_coding
description:
  NADH oxidoreductase hcr; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1984
symbol: EGV06029.1
gene_biotype: protein_coding
description:
  Oxidoreductase, FAD-dependent; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1986
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: HMPREF9952_1987
symbol: ArcC1
gene_biotype: protein_coding
description:
  Putative carbamate kinase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1991
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: HMPREF9952_1993
symbol: ArtJ
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 3; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: HMPREF9952_1996
symbol: EGV06135.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter, permease protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1997
symbol: GlnP
gene_biotype: protein_coding
description:
  ABC transporter, permease domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_1998
symbol: EGV06185.1
gene_biotype: protein_coding
description:
  Amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2000
symbol: trmL
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: HMPREF9952_2001
symbol: RsmD
gene_biotype: protein_coding
description:
  RNA methyltransferase, RsmD family; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: HMPREF9952_2002
symbol: FtsY
gene_biotype: protein_coding
description:
  Putative cell division protein FtsY; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2003
symbol: EGV06038.1
gene_biotype: protein_coding
description:
  SRP54-type protein, helical bundle domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2004
symbol: EGV05969.1
gene_biotype: protein_coding
description:
  SRP54-type protein, GTPase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2005
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: HMPREF9952_2006
symbol: FtsX
gene_biotype: protein_coding
description:
  Putative protein insertion permease FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: HMPREF9952_2009
symbol: metN
gene_biotype: protein_coding
description:
  D-methionine ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: HMPREF9952_2017
symbol: yihI
gene_biotype: protein_coding
description:
  Hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: HMPREF9952_2023
symbol: PsuT
gene_biotype: protein_coding
description:
  Na+ dependent nucleoside transporter; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2028
symbol: EGV04939.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 3; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2029
symbol: EGV04970.1
gene_biotype: protein_coding
description:
  ABC transporter, substrate-binding protein, family 3 domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2031
symbol: CdaR
gene_biotype: protein_coding
description:
  Putative sugar diacid recognition; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2035
symbol: YbjQ
gene_biotype: protein_coding
description:
  Hypothetical protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the UPF0145 family.


ensembl_gene_id: HMPREF9952_2036
symbol: rdgB
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: HMPREF9952_2037
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: HMPREF9952_2038
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: HMPREF9952_2040
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: HMPREF9952_2042
symbol: mviN
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: HMPREF9952_2043
symbol: rpsT
gene_biotype: protein_coding
description:
  30S ribosomal protein S20; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2044
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerC; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2045
symbol: EGV04943.1
gene_biotype: protein_coding
description:
  Phage integrase, N-terminal SAM domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2047
symbol: tpiA
gene_biotype: protein_coding
description:
  Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: HMPREF9952_2049
symbol: WaaA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: HMPREF9952_2050
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2052
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: HMPREF9952_2057
symbol: NadR
gene_biotype: protein_coding
description:
  Nicotinamide-nucleotide adenylyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2058
symbol: EGV04963.1
gene_biotype: protein_coding
description:
  DNA-binding helix-turn-helix protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2060
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: HMPREF9952_2061
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: HMPREF9952_2062
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: HMPREF9952_2063
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: HMPREF9952_2064
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]


ensembl_gene_id: HMPREF9952_2065
symbol: EGV04949.1
gene_biotype: protein_coding
description:
  P-43 domain protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_2066
symbol: EGV05859.1
gene_biotype: protein_coding
description:
  Putative translation elongation factor Tu; This gene contains a nucleotide ambiguity which may be the result of a sequencing error.


ensembl_gene_id: HMPREF9952_2067
symbol: lon
gene_biotype: protein_coding
description:
  Endopeptidase La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: HMPREF9952_2068
symbol: HemN_1
gene_biotype: protein_coding
description:
  Putative coproporphyrinogen dehydrogenase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: HMPREF9952_2069
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase A; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2070
symbol: serA
gene_biotype: protein_coding
description:
  Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: HMPREF9952_2076
symbol: rapA
gene_biotype: protein_coding
description:
  ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: HMPREF9952_2080
symbol: pflA
gene_biotype: protein_coding
description:
  Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: HMPREF9952_2083
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: HMPREF9952_2085
symbol: EGV07439.1
gene_biotype: protein_coding
description:
  Putative opacity-associated protein OapA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2086
symbol: EGV07454.1
gene_biotype: protein_coding
description:
  Opacity-associated protein A; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2089
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: HMPREF9952_2090
symbol: RelA
gene_biotype: protein_coding
description:
  RelA/SpoT domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2092
symbol: EGV07375.1
gene_biotype: protein_coding
description:
  ACT domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2093
symbol: DgkA
gene_biotype: protein_coding
description:
  Prokaryotic diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: HMPREF9952_2097
symbol: surE
gene_biotype: protein_coding
description:
  5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: HMPREF9952_2098
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: HMPREF9952_2100
symbol: rraB
gene_biotype: protein_coding
description:
  Hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: HMPREF9952_2107
symbol: gltX
gene_biotype: protein_coding
description:
  glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: HMPREF9952_2110
symbol: EGV07228.1
gene_biotype: protein_coding
description:
  ABC transporter transmembrane region; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2114
symbol: EGV07412.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid kinase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2115
symbol: kdkA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: HMPREF9952_2119
symbol: mltC
gene_biotype: protein_coding
description:
  Putative lipoprotein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: HMPREF9952_2120
symbol: EGV07201.1
gene_biotype: protein_coding
description:
  Putative Fe(2+)-trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: HMPREF9952_2122
symbol: EGV07377.1
gene_biotype: protein_coding
description:
  Base excision DNA repair protein, HhH-GPD family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2128
symbol: rpsR
gene_biotype: protein_coding
description:
  Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: HMPREF9952_2132
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: HMPREF9952_2133
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: HMPREF9952_2135
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: HMPREF9952_2139
symbol: folD
gene_biotype: protein_coding
description:
  Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: HMPREF9952_2142
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: HMPREF9952_2143
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: HMPREF9952_2147
symbol: fecD
gene_biotype: protein_coding
description:
  Iron-dicitrate transporter subunit FecD; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HMPREF9952_2148
symbol: fecC
gene_biotype: protein_coding
description:
  Fe(3+) dicitrate transport system permease protein FecC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: HMPREF9952_2155
symbol: EGV07106.1
gene_biotype: protein_coding
description:
  Cobalt transport domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2162
symbol: mltF
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: HMPREF9952_2163
symbol: deaD
gene_biotype: protein_coding
description:
  Cold-shock DEAD-box protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: HMPREF9952_2164
symbol: nlpI
gene_biotype: protein_coding
description:
  Lipoprotein NlpI; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2165
symbol: NlpI
gene_biotype: protein_coding
description:
  Lipoprotein NlpI domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2166
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: HMPREF9952_2167
symbol: EGV07199.1
gene_biotype: protein_coding
description:
  YhcH/YjgK/YiaL family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2170
symbol: polA
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: HMPREF9952_2171
symbol: EGV07181.1
gene_biotype: protein_coding
description:
  5'-3' exonuclease, N-terminal resolvase-like domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2172
symbol: ZapA
gene_biotype: protein_coding
description:
  Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: HMPREF9952_2174
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: HMPREF9952_2177
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: HMPREF9952_2179
symbol: rpoH
gene_biotype: protein_coding
description:
  Alternative sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: HMPREF9952_2182
symbol: plsY
gene_biotype: protein_coding
description:
  Acyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: HMPREF9952_2183
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: HMPREF9952_2188
symbol: EGV07113.1
gene_biotype: protein_coding
description:
  Hydrolase of X-linked nucleoside pyrophosphate N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2189
symbol: eno
gene_biotype: protein_coding
description:
  Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: HMPREF9952_2190
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: HMPREF9952_2192
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: HMPREF9952_2193
symbol: djlA
gene_biotype: protein_coding
description:
  Tellurite resistance protein TerB; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: HMPREF9952_2194
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: HMPREF9952_2195
symbol: rph
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: HMPREF9952_2196
symbol: YchM
gene_biotype: protein_coding
description:
  STAS domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2197
symbol: EGV07179.1
gene_biotype: protein_coding
description:
  Inorganic anion transporter, SulP domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2202
symbol: EGV07167.1
gene_biotype: protein_coding
description:
  Transketolase, thiamine pyrophosphate-binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2203
symbol: TktA
gene_biotype: protein_coding
description:
  Transketolase, pyridine binding domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the transketolase family.


ensembl_gene_id: HMPREF9952_2211
symbol: typA
gene_biotype: protein_coding
description:
  GTP-binding protein TypA; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2213
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: HMPREF9952_2216
symbol: slmA
gene_biotype: protein_coding
description:
  HTH-type protein SlmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: HMPREF9952_2217
symbol: dut
gene_biotype: protein_coding
description:
  dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: HMPREF9952_2218
symbol: EGV07476.1
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2219
symbol: coaBC
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2223
symbol: mutM
gene_biotype: protein_coding
description:
  DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: HMPREF9952_2224
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the universal ribosomal protein uL1 family.


ensembl_gene_id: HMPREF9952_2225
symbol: EGV07352.1
gene_biotype: protein_coding
description:
  Ribosomal protein L1p/L10e-like family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2226
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: HMPREF9952_2227
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: HMPREF9952_2228
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: HMPREF9952_2229
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: HMPREF9952_2230
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: HMPREF9952_2231
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: HMPREF9952_2234
symbol: frdD
gene_biotype: protein_coding
description:
  Fumarate reductase 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: HMPREF9952_2235
symbol: frdC
gene_biotype: protein_coding
description:
  Fumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane; Belongs to the FrdC family.


ensembl_gene_id: HMPREF9952_2236
symbol: frdB
gene_biotype: protein_coding
description:
  Fumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: HMPREF9952_2241
symbol: YjeA
gene_biotype: protein_coding
description:
  EF-P lysine aminoacylase GenX; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2242
symbol: EGV07170.1
gene_biotype: protein_coding
description:
  Tryptophan/tyrosine permease domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2243
symbol: sdaC
gene_biotype: protein_coding
description:
  Serine transporter; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2245
symbol: asnC
gene_biotype: protein_coding
description:
  Regulatory protein AsnC; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2249
symbol: glpB
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.


ensembl_gene_id: HMPREF9952_2250
symbol: glpA
gene_biotype: protein_coding
description:
  Anaerobic glycerol-3-phosphate dehydrogenase subunit A; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2251
symbol: EGV07299.1
gene_biotype: protein_coding
description:
  Anaerobic glycerol-3-phosphate dehydrogenase subunit A domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: HMPREF9952_2255
symbol: EGV07480.1
gene_biotype: protein_coding
description:
  RNA-directed DNA polymerase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2259
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: HMPREF9952_2260
symbol: queH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: HMPREF9952_2263
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: HMPREF9952_2269
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: HMPREF9952_2274
symbol: denV
gene_biotype: protein_coding
description:
  Deoxyribonuclease V; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2275
symbol: EGV07391.1
gene_biotype: protein_coding
description:
  Deoxyribonuclease V domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2277
symbol: RhaS_2
gene_biotype: protein_coding
description:
  AraC-type transcriptional regulator N-terminal domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a premature stop.


ensembl_gene_id: HMPREF9952_2281
symbol: YckI
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain one or more premature stops and/or frameshifts.


ensembl_gene_id: HMPREF9952_2289
symbol: EGV07324.1
gene_biotype: protein_coding
description:
  OsmC-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2301
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: HMPREF9952_2303
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: HMPREF9952_2304
symbol: GroEL
gene_biotype: protein_coding
description:
  Putative 60 kDa chaperonin; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2305
symbol: EGV07205.1
gene_biotype: protein_coding
description:
  Putative 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.


ensembl_gene_id: HMPREF9952_2306
symbol: EGV07333.1
gene_biotype: protein_coding
description:
  60 kDa chaperonin domain protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2307
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: HMPREF9952_2309
symbol: HcaT
gene_biotype: protein_coding
description:
  Transporter, major facilitator family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2310
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: HMPREF9952_2311
symbol: EGV07229.1
gene_biotype: protein_coding
description:
  Putative recombination associated protein; May be involved in recombination. Belongs to the RdgC family.


ensembl_gene_id: HMPREF9952_2317
symbol: murQ
gene_biotype: protein_coding
description:
  N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.


ensembl_gene_id: HMPREF9952_2318
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: HMPREF9952_2320
symbol: LutB
gene_biotype: protein_coding
description:
  Iron-sulfur cluster-binding protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2323
symbol: LldP
gene_biotype: protein_coding
description:
  Transporter, lactate permease family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: HMPREF9952_2326
symbol: TyrP_1
gene_biotype: protein_coding
description:
  Tryptophan/tyrosine permease family protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.


ensembl_gene_id: HMPREF9952_2331
symbol: EGV07135.1
gene_biotype: protein_coding
description:
  Putative uroporphyrinogen decarboxylase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the uroporphyrinogen decarboxylase family.


ensembl_gene_id: HMPREF9952_2332
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the uroporphyrinogen decarboxylase family.


ensembl_gene_id: HMPREF9952_2336
symbol: EGV07443.1
gene_biotype: protein_coding
description:
  5-formyltetrahydrofolate cyclo-ligase-like protein; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: HMPREF9952_2337
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: HMPREF9952_2338
symbol: cgtA
gene_biotype: protein_coding
description:
  Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: HMPREF9952_2340
symbol: yacG
gene_biotype: protein_coding
description:
  Hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: HMPREF9952_2341
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: HMPREF9952_2347
symbol: rppH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: HMPREF9952_2349
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: HMPREF9952_2350
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: HMPREF9952_2351
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


