# pathwayInfo

id: SM01183
description: Elongation factor 1 gamma, conserved domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01183
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01183_Elongation_factor_1_gamma,_conserved_domain


id: SM01191
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01191
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01191_This_presumed_domain_is_named_after_Emsy_N_Terminus_(ENT)._Emsy_is_a_protein_that_is_amplified_in_breast_cancer_and_interacts_with_BRCA2._The_N_terminus_of_this_protein_is_found_to_be_similar_to_other_vertebrate_and_plant_proteins_of_unknown_...

description:
  This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown ...


id: SM01194
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01194
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01194_The_release_factor_eRF1_terminates_protein_biosynthesis_by_recognising_stop_codons_at_the_A_site_of_the_ribosome_and_stimulating_peptidyl-tRNA_bond_hydrolysis_at_the_peptidyl_transferase_centre._The_crystal_structure_of_human_eRF1_is_known_...

description:
  The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known ...


id: SM01199
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01199
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01199_The_FDF_domain,_so_called_because_of_the_conserved_FDF_at_its_N_termini,_is_an_entirely_alpha-helical_domain_with_multiple_exposed_hydrophilic_loops._It_is_found_at_the_C_terminus_of_Scd6p-like_SM_domains._It_is_also_found_with_other_divergent_Sm_...

description:
  The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C terminus of Scd6p-like SM domains. It is also found with other divergent Sm ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01214
description: RNA pol II promoter Fmp27 protein domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01214
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01214_RNA_pol_II_promoter_Fmp27_protein_domain


id: SM01218
description: C-terminal duplication domain of Friend of PRMT1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01218
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01218_C-terminal_duplication_domain_of_Friend_of_PRMT1


id: SM01225
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01225
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01225_This_domain_is_found_in_disease_proteins_PKHD1_and_KIAA1199_and_is_named_G8_after_its_8_conserved_glycines._It_is_predicted_to_contain_10_beta_strands_and_an_alpha_helix.

description:
  This domain is found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix.


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01234
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01234
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01234_This_domain_has_haemolytic_activity_(PMID:19306042)._It_is_found_in_short_(73-103_amino_acid)_proteins_and_contains_three_conserved_cysteine_residues.

description:
  This domain has haemolytic activity (PMID:19306042). It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.


id: SM01238
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01238
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01238_This_domain_is_found_in_fungal_proteins_and_contains_a_conserved_IGR_motif._Its_function_is_unknown.

description:
  This domain is found in fungal proteins and contains a conserved IGR motif. Its function is unknown.


id: SM01252
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01252
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01252_Conserved_DNA-binding_domain_that_is_found_in_a_wide_range_of_proteins_of_large_bacterial_and_eukaryotic_DNA_viruses.

description:
  Conserved DNA-binding domain that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses.


id: SM01253
description: Domain of Kin17 curved DNA-binding protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01253
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01253_Domain_of_Kin17_curved_DNA-binding_protein


id: SM01272
description: This domain is found associated with Lsm domain PMID:16115810.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01272
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01272_This_domain_is_found_associated_with_Lsm_domain_PMID:16115810.


id: SM01281
description: Transcription mediator complex subunit Med12
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01281
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01281_Transcription_mediator_complex_subunit_Med12


id: SM01283
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01283
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01283_This_domain_is_found_both_alone_and_at_the_C-terminus_of_actin-binding_Rho-activating_protein_(ABRA)._It_binds_to_actin,_and_in_muscle_regulates_the_actin_cytoskeleton_and_cell_motility_PMID:11983702,_20940261._It_has_a_winged_helix-like_fold_...

description:
  This domain is found both alone and at the C-terminus of actin-binding Rho-activating protein (ABRA). It binds to actin, and in muscle regulates the actin cytoskeleton and cell motility PMID:11983702, 20940261. It has a winged helix-like fold ...


id: SM01285
description: FACT complex subunit SPT16 N-terminal lobe domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01285
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01285_FACT_complex_subunit_SPT16_N-terminal_lobe_domain


id: SM01296
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01296
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01296_This_family_features_sequences_that_are_similar_to_a_region_of_hypothetical_yeast_gene_product_N2227._This_is_thought_to_be_expressed_during_meiosis_and_may_be_involved_in_the_defence_response_to_stressful_conditions_PMID:8771715.

description:
  This family features sequences that are similar to a region of hypothetical yeast gene product N2227. This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions PMID:8771715.


id: SM01313
description: Exocyst complex component SEC3 N-terminal PIP2 binding PH
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01313
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01313_Exocyst_complex_component_SEC3_N-terminal_PIP2_binding_PH


id: SM01314
description: Snf2-ATP coupling, chromatin remodelling complex
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01314
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01314_Snf2-ATP_coupling,_chromatin_remodelling_complex


id: SM01326
description: C2 domain of PTEN tumour-suppressor protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01326
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01326_C2_domain_of_PTEN_tumour-suppressor_protein


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01332
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01332
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01332_Cyclins_are_a_family_of_proteins_that_control_the_progression_of_cells_through_the_cell_cycle_by_activating_cyclin-dependent_kinase_(Cdk)_enzymes.

description:
  Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.


id: SM01335
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01335
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01335_This_domain_is_found_in_poly(ADP-ribose)-synthetases_(PMID:15112237)._The_function_of_this_domain_is_unknown.

description:
  This domain is found in poly(ADP-ribose)-synthetases (PMID:15112237). The function of this domain is unknown.


id: SM01336
description: Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01336
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01336_Poly(ADP-ribose)_polymerase_and_DNA-Ligase_Zn-finger_region


id: SM01337
description: Anaphase-promoting complex, subunit 10 (APC10)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01337
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01337_Anaphase-promoting_complex,_subunit_10_(APC10)


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01343
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01343
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01343_The_FATC_domain_is_named_after_FRAP,_ATM,_TRRAP_C-terminal_(PMID:10782091)._The_solution_structure_of_the_FATC_domain_suggests_it_plays_a_role_in_redox-dependent_structural_and_cellular_stability_(PMID:15772072).

description:
  The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072).


id: SM01344
description: This is domain B in the catalytic subunit of DNA-dependent protein kinases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01344
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01344_This_is_domain_B_in_the_catalytic_subunit_of_DNA-dependent_protein_kinases.


id: SM01349
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01349
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01349_XMAP215/Dis1_proteins,_such_as_Alp14_and_XMAP215,_increase_microtubules_dynamic_polymerization_rates_by_recruiting_soluble_αβ-tubulin_via_their_conserved_TOG_domains_to_polymerizing_microtubule_plus_ends.

description:
  XMAP215/Dis1 proteins, such as Alp14 and XMAP215, increase microtubules dynamic polymerization rates by recruiting soluble αβ-tubulin via their conserved TOG domains to polymerizing microtubule plus ends.


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01368
description: Retinoblastoma-associated protein A domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01368
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01368_Retinoblastoma-associated_protein_A_domain


id: SM01371
description: Transcription factor IIA, alpha/beta subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01371
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01371_Transcription_factor_IIA,_alpha/beta_subunit


id: SM01372
description: E2F/DP family winged-helix DNA-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01372
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01372_E2F/DP_family_winged-helix_DNA-binding_domain


id: SM01376
description: Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01376
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01376_Eukaryotic_elongation_factor_5A_hypusine,_DNA-binding_OB_fold


id: SM01377
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01377
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01377_Bovine_L40_has_been_identified_as_a_secondary_RNA_binding_protein_(PMID:3129699)._L40_is_fused_to_a_ubiquitin_protein_(PMID:7488009).

description:
  Bovine L40 has been identified as a secondary RNA binding protein (PMID:3129699). L40 is fused to a ubiquitin protein (PMID:7488009).


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01385
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01385
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01385_This_family_contains_the_breast_cancer_tumour_suppressor_BRCA2-interacting_protein_DSS1_and_its_homologue_SEM1,_both_of_which_are_short_acidic_proteins._DSS1_has_been_shown_to_be_a_conserved_component_of_the_Rae1_mediated_mRNA_export_pathway_in_...

description:
  This family contains the breast cancer tumour suppressor BRCA2-interacting protein DSS1 and its homologue SEM1, both of which are short acidic proteins. DSS1 has been shown to be a conserved component of the Rae1 mediated mRNA export pathway in ...


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01393
description: This family includes ribosomal protein L32 from eukaryotes and archaebacteria.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01393
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01393_This_family_includes_ribosomal_protein_L32_from_eukaryotes_and_archaebacteria.


id: SM01395
description: Transcription factor TFIIH complex subunit Tfb5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01395
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01395_Transcription_factor_TFIIH_complex_subunit_Tfb5


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01406
description: Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01406
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01406_Family_of_proteins_with_a_conserved_region_found_in_PAPA-1,_a_PAP-1_binding_protein.


id: SM01408
description: Inhibitor of growth proteins N-terminal histone-binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01408
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01408_Inhibitor_of_growth_proteins_N-terminal_histone-binding


id: SM01419
description: Alpha-macro-globulin thiol-ester bond-forming region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01419
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01419_Alpha-macro-globulin_thiol-ester_bond-forming_region


id: SM01477
description: DDE transposase retroviral integrase sub-family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01477
name:
  Protein Domains (SMART).STRING_v12.0_105231_STRINGid_SM01477_DDE_transposase_retroviral_integrase_sub-family


