# geneInfo

ensembl_gene_id: MEALZ_0001
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: MEALZ_0002
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: MEALZ_0003
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: MEALZ_0004
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: MEALZ_0008
symbol: CCE21712.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MEALZ_0015
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein tatA/E homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: MEALZ_0016
symbol: tatB
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: MEALZ_0017
symbol: CCE21721.1
gene_biotype: protein_coding
description:
  Putative oxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0018
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: MEALZ_0019
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: MEALZ_0024
symbol: CCE21728.1
gene_biotype: protein_coding
description:
  Putative OsmC-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype.


ensembl_gene_id: MEALZ_0025
symbol: speD
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.


ensembl_gene_id: MEALZ_0026
symbol: CCE21730.1
gene_biotype: protein_coding
description:
  Putative cysteine peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0027
symbol: CCE21731.1
gene_biotype: protein_coding
description:
  Putative Outer membrane autotransporter barrel domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0041
symbol: CCE21745.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MEALZ_0045
symbol: CCE21749.1
gene_biotype: protein_coding
description:
  CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_0047
symbol: CCE21751.1
gene_biotype: protein_coding
description:
  Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0048
symbol: CCE21752.1
gene_biotype: protein_coding
description:
  Putative serine/threonine-protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0050
symbol: CCE21754.1
gene_biotype: protein_coding
description:
  Putative signal transduction histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0055
symbol: CCE21759.1
gene_biotype: protein_coding
description:
  Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_0057
symbol: CCE21761.1
gene_biotype: protein_coding
description:
  Putative sulfotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0059
symbol: CCE21763.1
gene_biotype: protein_coding
description:
  Putative S-adenosyl-L-methionine-dependent methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0063
symbol: CCE21767.1
gene_biotype: protein_coding
description:
  Putative exopolysaccharide biosynthesis glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0064
symbol: galE
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase) CapN-like; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0067
symbol: CCE21771.1
gene_biotype: protein_coding
description:
  Putative Polysaccharide biosynthesis protein CapD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0072
symbol: typA
gene_biotype: protein_coding
description:
  GTP-binding protein TypA/BipA (Tyrosine phosphorylated protein A); Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MEALZ_0073
symbol: hisB
gene_biotype: protein_coding
description:
  Imidazoleglycerol-phosphate dehydratase (IGPD); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0074
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: MEALZ_0075
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0076
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: MEALZ_0077
symbol: hisI
gene_biotype: protein_coding
description:
  Phosphoribosyl-AMP cyclohydrolase (PRA-CH); Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: MEALZ_0078
symbol: hisE
gene_biotype: protein_coding
description:
  Phosphoribosyl-ATP pyrophosphatase (PRA-PH); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0080
symbol: tatB-2
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatB subunit (fragment); Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: MEALZ_0081
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: MEALZ_0086
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: MEALZ_0087
symbol: plsY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: MEALZ_0088
symbol: tsaD
gene_biotype: protein_coding
description:
  Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: MEALZ_0089
symbol: rpsU
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S21; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: MEALZ_0091
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: MEALZ_0092
symbol: rpoD
gene_biotype: protein_coding
description:
  Sigma D (sigma 70) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: MEALZ_0093
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase (Methionine adenosyltransferase) (AdoMet synthetase) (MAT); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: MEALZ_0094
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase); May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: MEALZ_0095
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Function of strongly homologous gene; enzyme; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: MEALZ_0096
symbol: rsmE
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: MEALZ_0098
symbol: CCE21802.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0234 family.


ensembl_gene_id: MEALZ_0099
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase (CCA-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: MEALZ_0101
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: MEALZ_0102
symbol: guaA
gene_biotype: protein_coding
description:
  GMP synthase [glutamine-hydrolyzing] (Glutamine amidotransferase) (GMP synthetase); Catalyzes the synthesis of GMP from XMP.


ensembl_gene_id: MEALZ_0103
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: MEALZ_0104
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.


ensembl_gene_id: MEALZ_0110
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: MEALZ_0114
symbol: CCE21815.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative ABC transporter; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_0115
symbol: CCE21816.1
gene_biotype: protein_coding
description:
  Putative ABC-type transport system, ATPase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_0117
symbol: CCE21818.1
gene_biotype: protein_coding
description:
  Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0119
symbol: CCE21820.1
gene_biotype: protein_coding
description:
  Putative SCO1/SenC family protein/methylamine utilization protein MauG; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0124
symbol: CCE21825.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: MEALZ_0125
symbol: pilT
gene_biotype: protein_coding
description:
  Pilus retraction protein PilT; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MEALZ_0127
symbol: djlA
gene_biotype: protein_coding
description:
  DnaJ-like protein djlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: MEALZ_0128
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SAICAR synthetase family.


ensembl_gene_id: MEALZ_0129
symbol: radC
gene_biotype: protein_coding
description:
  DNA repair protein RadC homolog; Function of strongly homologous gene; cell process; Belongs to the UPF0758 family.


ensembl_gene_id: MEALZ_0130
symbol: coaB
gene_biotype: protein_coding
description:
  Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: MEALZ_0131
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (dUTP pyrophosphatase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: MEALZ_0133
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase (NAG kinase) (AGK) (N-acetyl-L-glutamate 5-phosphotransferase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: MEALZ_0136
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: MEALZ_0139
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: MEALZ_0141
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: MEALZ_0149
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: MEALZ_0150
symbol: trpG
gene_biotype: protein_coding
description:
  Anthranilate synthase component II (Glutamine amido-transferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0151
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: MEALZ_0154
symbol: qseB
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein QseB; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_0155
symbol: yggW
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen-III oxidase-like protein yggW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: MEALZ_0156
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase (OPRT) (OPRTase); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: MEALZ_0158
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: MEALZ_0159
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: MEALZ_0160
symbol: aroG
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: MEALZ_0175
symbol: mepA
gene_biotype: protein_coding
description:
  Penicillin-insensitive murein endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.


ensembl_gene_id: MEALZ_0176
symbol: tpm
gene_biotype: protein_coding
description:
  Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: MEALZ_0181
symbol: aqpZ
gene_biotype: protein_coding
description:
  Fragment of water channel (aquaporin Z) (MIP family) (part 2); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_0194
symbol: CCE21895.1
gene_biotype: protein_coding
description:
  Putative plasmid addiction system, toxin protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0201
symbol: CCE21901.1
gene_biotype: protein_coding
description:
  Putative transposase, IS21 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: MEALZ_0202
symbol: CCE21902.1
gene_biotype: protein_coding
description:
  Putative helper of transposition protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: MEALZ_0214
symbol: hppA
gene_biotype: protein_coding
description:
  Putative K(+)-stimulated pyrophosphate-energized sodium pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.


ensembl_gene_id: MEALZ_0215
symbol: fdsD
gene_biotype: protein_coding
description:
  NAD-linked formate dehydrogenase, molybdenum containing, delta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0216
symbol: fdsC
gene_biotype: protein_coding
description:
  NAD-linked formate dehydrogenase, molybdenum containing, accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: MEALZ_0217
symbol: fdsA
gene_biotype: protein_coding
description:
  NAD-linked formate dehydrogenase, molybdenum containing, alpha subunit (fragment); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: MEALZ_0222
symbol: CCE21922.1
gene_biotype: protein_coding
description:
  Putative NAD(P)-binding domain enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0226
symbol: CCE21926.1
gene_biotype: protein_coding
description:
  Putative toxin secretion ABC transporter ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0227
symbol: CCE21927.1
gene_biotype: protein_coding
description:
  Putative Bacterial type II secretion system protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_0231
symbol: CCE21931.1
gene_biotype: protein_coding
description:
  Putative SNARE associated Golgi protein-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0243
symbol: CCE21943.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: MEALZ_0251
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate/thiosulfate import ATP-binding protein CysA (Sulfate-transporting ATPase); Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.


ensembl_gene_id: MEALZ_0252
symbol: cysW
gene_biotype: protein_coding
description:
  Sulfate transport system permease protein CysW; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_0253
symbol: cysT
gene_biotype: protein_coding
description:
  Sulfate transport system permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: MEALZ_0254
symbol: sbp
gene_biotype: protein_coding
description:
  Sulfate-binding protein precursor (Sulfate starvation-induced protein 2) (SSI2); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_0258
symbol: CCE21958.1
gene_biotype: protein_coding
description:
  Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0262
symbol: CCE21962.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: MEALZ_0264
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-(Acyl carrier protein) reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0266
symbol: CCE21966.1
gene_biotype: protein_coding
description:
  Putative 1-phosphofructokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: MEALZ_0268
symbol: CCE21968.1
gene_biotype: protein_coding
description:
  Putative sensory transduction system regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0274
symbol: cydA
gene_biotype: protein_coding
description:
  Cytochrome bd ubiquinol oxidase subunit I; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: MEALZ_0275
symbol: cydB
gene_biotype: protein_coding
description:
  Cytochrome bd ubiquinol oxidase subunit II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0278
symbol: CCE21978.1
gene_biotype: protein_coding
description:
  Putative ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0280
symbol: CCE21980.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function, DUF336; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_0281
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase class II (fumarase C); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: MEALZ_0287
symbol: korB
gene_biotype: protein_coding
description:
  Putative 2-oxoglutarate ferredoxin oxidoreductase, beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0288
symbol: korA
gene_biotype: protein_coding
description:
  Putative 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0298
symbol: CCE21998.1
gene_biotype: protein_coding
description:
  Putative Toxin-antitoxin system, antitoxin component, Xre family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0302
symbol: CCE22002.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent (modular protein); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: MEALZ_0306
symbol: comM
gene_biotype: protein_coding
description:
  Competence protein ComM; Function of homologous gene experimentally demonstrated in an other organism; cell process.


ensembl_gene_id: MEALZ_0310
symbol: acnA
gene_biotype: protein_coding
description:
  Aconitate hydratase (Citrate hydro-lyase) (Aconitase); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.


ensembl_gene_id: MEALZ_0311
symbol: copB
gene_biotype: protein_coding
description:
  Putative copper-exporting P-type ATPase B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0312
symbol: CCE22012.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: MEALZ_0317
symbol: CCE22017.1
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0320
symbol: CCE22020.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative transglutaminase; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_0322
symbol: CCE22022.1
gene_biotype: protein_coding
description:
  Putative AAA ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0324
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: MEALZ_0325
symbol: gidB
gene_biotype: protein_coding
description:
  Methyltransferase gidB (Glucose-inhibited division protein B); Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: MEALZ_0326
symbol: parA
gene_biotype: protein_coding
description:
  Chromosome partitioning protein; Function of homologous gene experimentally demonstrated in an other organism; cell process.


ensembl_gene_id: MEALZ_0327
symbol: parB
gene_biotype: protein_coding
description:
  Chromosome partitioning protein ParB; Function of strongly homologous gene; cell process; Belongs to the ParB family.


ensembl_gene_id: MEALZ_0329
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: MEALZ_0330
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: MEALZ_0331
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: MEALZ_0332
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: MEALZ_0333
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha (ATPase subunit alpha) (ATP synthase F1 sector subunit alpha); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: MEALZ_0334
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase gamma chain (ATP synthase F1 sector gamma subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: MEALZ_0335
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase subunit beta (ATPase subunit beta) (ATP synthase F1 sector subunit beta); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: MEALZ_0336
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain (ATP synthase F1 sector epsilon subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: MEALZ_0337
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: MEALZ_0338
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: MEALZ_0344
symbol: CCE22044.1
gene_biotype: protein_coding
description:
  Putative HsdS polypeptide, part of CfrA family (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0361
symbol: pcm
gene_biotype: protein_coding
description:
  Protein-L-isoaspartate O-methyltransferase 2; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: MEALZ_0363
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase pncB2; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: MEALZ_0370
symbol: rhlE
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: MEALZ_0373
symbol: CCE22073.1
gene_biotype: protein_coding
description:
  Putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0374
symbol: yedZ
gene_biotype: protein_coding
description:
  Sulfoxide reductase heme-binding subunit yedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...]


ensembl_gene_id: MEALZ_0375
symbol: CCE22075.1
gene_biotype: protein_coding
description:
  Putative NADH dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0376
symbol: phr
gene_biotype: protein_coding
description:
  Deoxyribodipyrimidine photo-lyase; Function of strongly homologous gene; putative enzyme; Belongs to the DNA photolyase family.


ensembl_gene_id: MEALZ_0377
symbol: CCE22077.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein blc; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: MEALZ_0385
symbol: relA
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: MEALZ_0386
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I (POL I); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: MEALZ_0387
symbol: CCE22087.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0389
symbol: engB
gene_biotype: protein_coding
description:
  Putative GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: MEALZ_0394
symbol: CCE22094.1
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: MEALZ_0395
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: MEALZ_0396
symbol: ycgR
gene_biotype: protein_coding
description:
  YcgR family protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: MEALZ_0403
symbol: CCE22103.1
gene_biotype: protein_coding
description:
  Putative TrkA-N domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0404
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: MEALZ_0405
symbol: rraA
gene_biotype: protein_coding
description:
  Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: MEALZ_0410
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: MEALZ_0411
symbol: CCE22111.1
gene_biotype: protein_coding
description:
  Putative nuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0419
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III (DNA-(apurinic or apyrimidinic site) lyase); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: MEALZ_0420
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: MEALZ_0421
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: MEALZ_0422
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: MEALZ_0423
symbol: rnfC-2
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfC (fragment); Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: MEALZ_0424
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: MEALZ_0425
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: MEALZ_0428
symbol: rfbD
gene_biotype: protein_coding
description:
  Putative GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: MEALZ_0429
symbol: fcl
gene_biotype: protein_coding
description:
  Bifunctional GDP-fucose synthetase (GDP-4-dehydro-6-deoxy-D-mannose epimerase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: MEALZ_0430
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: MEALZ_0431
symbol: ggp
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: MEALZ_0432
symbol: trmL
gene_biotype: protein_coding
description:
  Putative RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: MEALZ_0434
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: MEALZ_0435
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: MEALZ_0439
symbol: CCE22138.1
gene_biotype: protein_coding
description:
  Peptidase S41A, C-terminal protease; Function of strongly homologous gene; enzyme; Belongs to the peptidase S41A family.


ensembl_gene_id: MEALZ_0444
symbol: CCE22143.1
gene_biotype: protein_coding
description:
  Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0446
symbol: CCE22145.1
gene_biotype: protein_coding
description:
  Putative Glyceraldehyde-3-phosphate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: MEALZ_0454
symbol: fadA
gene_biotype: protein_coding
description:
  Acetyl-CoA acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: MEALZ_0460
symbol: CCE22159.1
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MEALZ_0461
symbol: argJ
gene_biotype: protein_coding
description:
  Arginine biosynthesis bifunctional protein ArgJ alpha chain; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: MEALZ_0465
symbol: CCE22164.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulators (CopG/Arc/MetJ DNA-binding domain); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0467
symbol: CCE22166.1
gene_biotype: protein_coding
description:
  Putative plasmid maintenance system antidote protein, XRE family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0476
symbol: CCE22174.1
gene_biotype: protein_coding
description:
  Putative Bacterial type II secretion system protein F domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0478
symbol: CCE22176.1
gene_biotype: protein_coding
description:
  Exported protein of unknown function; No homology to any previously reported sequences; Belongs to the bacterial secretin family.


ensembl_gene_id: MEALZ_0493
symbol: kefB
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: MEALZ_0494
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...]


ensembl_gene_id: MEALZ_0495
symbol: yajC
gene_biotype: protein_coding
description:
  Putative Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: MEALZ_0496
symbol: secD
gene_biotype: protein_coding
description:
  Putative protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: MEALZ_0497
symbol: secF
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: MEALZ_0500
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: MEALZ_0501
symbol: rlmN-2
gene_biotype: protein_coding
description:
  Putative Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: MEALZ_0503
symbol: hisS
gene_biotype: protein_coding
description:
  Histidine tRNA synthetase (Histidine--tRNA ligase) (HisRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0505
symbol: bamB
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: MEALZ_0506
symbol: engA
gene_biotype: protein_coding
description:
  GTP-binding protein EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: MEALZ_0518
symbol: CCE22216.1
gene_biotype: protein_coding
description:
  Putative thiol-Disulfide oxidoreductase DCC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0523
symbol: metH
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: MEALZ_0537
symbol: CCE22235.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein (subunit C); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_0538
symbol: CCE22236.1
gene_biotype: protein_coding
description:
  ABC transporter permease component (subunit B); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_0541
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: MEALZ_0542
symbol: rhlE-2
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DEAD box helicase family.


ensembl_gene_id: MEALZ_0543
symbol: oadB
gene_biotype: protein_coding
description:
  Putative oxaloacetate decarboxylase beta chain; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.


ensembl_gene_id: MEALZ_0546
symbol: CCE22244.1
gene_biotype: protein_coding
description:
  Putative TonB-dependent receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.


ensembl_gene_id: MEALZ_0547
symbol: CCE22245.1
gene_biotype: protein_coding
description:
  Putative monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0548
symbol: CCE22246.1
gene_biotype: protein_coding
description:
  Putative bipartite protein [includes a nickel-iron hydrogenase, accessory protein domain HupE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.


ensembl_gene_id: MEALZ_0550
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: MEALZ_0551
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-binding protein ErpA (Iron-sulfur cluster insertion protein); Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: MEALZ_0552
symbol: anmK
gene_biotype: protein_coding
description:
  Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: MEALZ_0554
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosyl-tRNA synthetase (Tyrosine--tRNA ligase) (TyrRS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: MEALZ_0562
symbol: uup
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein Uup; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_0565
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: MEALZ_0569
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase (PNP synthase); Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: MEALZ_0571
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: MEALZ_0572
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: MEALZ_0574
symbol: CCE22269.1
gene_biotype: protein_coding
description:
  Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family.


ensembl_gene_id: MEALZ_0575
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: MEALZ_0577
symbol: CCE22272.1
gene_biotype: protein_coding
description:
  Putative sigma-E factor regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0579
symbol: rpoE
gene_biotype: protein_coding
description:
  RNA polymerase sigma-E factor (Sigma-24); Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: MEALZ_0580
symbol: nadB
gene_biotype: protein_coding
description:
  L-aspartate oxidase (LASPO) (Quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.


ensembl_gene_id: MEALZ_0590
symbol: pip
gene_biotype: protein_coding
description:
  Putative proline iminopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase S33 family.


ensembl_gene_id: MEALZ_0591
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase (Polyprenyl p-hydroxybenzoate decarboxylase); Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: MEALZ_0595
symbol: pqqE
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: MEALZ_0598
symbol: pqqC
gene_biotype: protein_coding
description:
  Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: MEALZ_0599
symbol: pqqB
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: MEALZ_0600
symbol: pqqA
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein A; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide; Belongs to the PqqA family.


ensembl_gene_id: MEALZ_0603
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: MEALZ_0608
symbol: CCE22303.1
gene_biotype: protein_coding
description:
  Putative Peptidoglycan-binding domain 1 protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0611
symbol: CCE22306.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, ATP-binding family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_0614
symbol: sps
gene_biotype: protein_coding
description:
  Sucrose-phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0615
symbol: spp
gene_biotype: protein_coding
description:
  Sucrose-6F-phosphate phosphohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0617
symbol: ams
gene_biotype: protein_coding
description:
  Putative amylosucrase, alpha-amylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.


ensembl_gene_id: MEALZ_0622
symbol: CCE22317.1
gene_biotype: protein_coding
description:
  Putative potassium channel; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_0626
symbol: CCE22321.1
gene_biotype: protein_coding
description:
  Putative synthetase/amidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0630
symbol: CCE22325.1
gene_biotype: protein_coding
description:
  Putative stringent starvation protein A; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_0633
symbol: petB
gene_biotype: protein_coding
description:
  Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: MEALZ_0634
symbol: petA
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase iron-sulfur subunit (Rieske iron-sulfur protein) (RISP); Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: MEALZ_0635
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase 2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: MEALZ_0636
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase (HDH); Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: MEALZ_0637
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase (ATP-PRTase) (ATP-PRT); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: MEALZ_0638
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: MEALZ_0640
symbol: CCE22335.1
gene_biotype: protein_coding
description:
  Putative ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_0644
symbol: kdsD
gene_biotype: protein_coding
description:
  Arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0645
symbol: CCE22340.1
gene_biotype: protein_coding
description:
  Putative 3-Deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P phosphatase) kdsC-like; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: MEALZ_0647
symbol: lptA
gene_biotype: protein_coding
description:
  Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: MEALZ_0649
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: MEALZ_0650
symbol: rpoX
gene_biotype: protein_coding
description:
  Sigma(54) modulation protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MEALZ_0653
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: MEALZ_0654
symbol: minD
gene_biotype: protein_coding
description:
  Septum site-determining protein MinD (Cell division inhibitor MinD); Function of homologous gene experimentally demonstrated in an other organism; cell process.


ensembl_gene_id: MEALZ_0655
symbol: minC
gene_biotype: protein_coding
description:
  Putative septum site-determining protein minC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: MEALZ_0656
symbol: CCE22351.1
gene_biotype: protein_coding
description:
  Putative phosphate permease jhp_1384; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0657
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: MEALZ_0661
symbol: CCE22356.1
gene_biotype: protein_coding
description:
  Putative MxaK protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0662
symbol: CCE22357.1
gene_biotype: protein_coding
description:
  Putative MxaL protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0664
symbol: fliW
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.


ensembl_gene_id: MEALZ_0665
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase alpha chain; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: MEALZ_0666
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: MEALZ_0667
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase) (KPHMT); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: MEALZ_0668
symbol: folK
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_0669
symbol: pcnB
gene_biotype: protein_coding
description:
  Poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: MEALZ_0675
symbol: pepA
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase (Leucine aminopeptidase) (LAP) (Leucyl aminopeptidase); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: MEALZ_0677
symbol: valS
gene_biotype: protein_coding
description:
  Valyl-tRNA synthetase (Valine--tRNA ligase) (ValRS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: MEALZ_0678
symbol: pilB
gene_biotype: protein_coding
description:
  Type 4 fimbrial assembly protein pilB; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MEALZ_0679
symbol: pilC
gene_biotype: protein_coding
description:
  Type 4 fimbrial assembly protein; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MEALZ_0680
symbol: pilD
gene_biotype: protein_coding
description:
  Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: MEALZ_0681
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: MEALZ_0682
symbol: zapD
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: MEALZ_0683
symbol: yacG
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: MEALZ_0687
symbol: CCE22382.1
gene_biotype: protein_coding
description:
  Putative Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-de [...]


ensembl_gene_id: MEALZ_0697
symbol: CCE22392.1
gene_biotype: protein_coding
description:
  Putative sodium-dependent transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0699
symbol: CCE22394.1
gene_biotype: protein_coding
description:
  Putative Serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0708
symbol: glyQ
gene_biotype: protein_coding
description:
  Glycine tRNA synthetase, alpha subunit (Glycine--tRNA ligase alpha chain) (GlyRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0709
symbol: glyS
gene_biotype: protein_coding
description:
  Glycine tRNA synthetase, beta subunit (Glycine--tRNA ligase beta chain) (GlyRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0712
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: MEALZ_0715
symbol: CCE22410.1
gene_biotype: protein_coding
description:
  Putative H(+)/Cl(-) exchange transporter ClcA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_0717
symbol: ribA
gene_biotype: protein_coding
description:
  Riboflavin-specific deaminase/GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: MEALZ_0719
symbol: ygcM
gene_biotype: protein_coding
description:
  Putative 6-pyruvoyl tetrahydrobiopterin synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0722
symbol: CCE22417.1
gene_biotype: protein_coding
description:
  Putative helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0730
symbol: CCE22425.1
gene_biotype: protein_coding
description:
  Putative pyridoxal phosphate-dependent aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: MEALZ_0733
symbol: CCE22428.1
gene_biotype: protein_coding
description:
  Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0734
symbol: tagD
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate cytidylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0735
symbol: CCE22430.1
gene_biotype: protein_coding
description:
  Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0739
symbol: CCE22434.1
gene_biotype: protein_coding
description:
  Putative PLP-dependent transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: MEALZ_0740
symbol: CCE22435.1
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0741
symbol: CCE22436.1
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0743
symbol: CCE22438.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent carboligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0744
symbol: CCE22439.1
gene_biotype: protein_coding
description:
  Putative lipopolysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0746
symbol: lafA
gene_biotype: protein_coding
description:
  Lateral flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: MEALZ_0747
symbol: CCE22442.1
gene_biotype: protein_coding
description:
  Putative Flagellar protein FlaG protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0748
symbol: CCE22443.1
gene_biotype: protein_coding
description:
  Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: MEALZ_0755
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein (Fifty-four homolog); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into th [...]


ensembl_gene_id: MEALZ_0756
symbol: rpsP
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S16; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: MEALZ_0757
symbol: rimM
gene_biotype: protein_coding
description:
  Ribosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: MEALZ_0758
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase) (M1G-methyltransferase) (tRNA [GM37] methyltransferase); Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: MEALZ_0759
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: MEALZ_0761
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: MEALZ_0762
symbol: lpxA
gene_biotype: protein_coding
description:
  Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: MEALZ_0767
symbol: CCE22462.1
gene_biotype: protein_coding
description:
  Squalene monooxygenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0771
symbol: arcB
gene_biotype: protein_coding
description:
  Ornithine cyclodeaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0775
symbol: CCE22470.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MEALZ_0776
symbol: CCE22471.1
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: MEALZ_0780
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: MEALZ_0802
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: MEALZ_0815
symbol: CCE22509.1
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: MEALZ_0816
symbol: mltF
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: MEALZ_0820
symbol: CCE22514.1
gene_biotype: protein_coding
description:
  Exported protein of unknown function; No homology to any previously reported sequences; Belongs to the peptidase S1B family.


ensembl_gene_id: MEALZ_0821
symbol: CCE22515.1
gene_biotype: protein_coding
description:
  Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_0824
symbol: hisI-2
gene_biotype: protein_coding
description:
  Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: MEALZ_0825
symbol: CCE22519.1
gene_biotype: protein_coding
description:
  Putative cobalamin synthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0829
symbol: CCE22523.1
gene_biotype: protein_coding
description:
  Putative formylmethanofurane dehydrogenase, subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0830
symbol: CCE22524.1
gene_biotype: protein_coding
description:
  Putative Uncharacterized GTP-binding protein yjiA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0833
symbol: bpt
gene_biotype: protein_coding
description:
  Putative arginyl-tRNA--protein transferase (R-transferase) (Arginyltransferase) Ate-like; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: MEALZ_0834
symbol: aat
gene_biotype: protein_coding
description:
  Leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: MEALZ_0835
symbol: trxB
gene_biotype: protein_coding
description:
  Thioredoxin reductase, FAD/NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0837
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: MEALZ_0840
symbol: dsrE
gene_biotype: protein_coding
description:
  Putative sulfurtransferase dsrE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0848
symbol: fsa2
gene_biotype: protein_coding
description:
  Putative fructose-6-phosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.


ensembl_gene_id: MEALZ_0849
symbol: aph
gene_biotype: protein_coding
description:
  Putative phosphotransferase:kinase; Homologs of previously reported genes of unknown function; Belongs to the fructosamine kinase family.


ensembl_gene_id: MEALZ_0856
symbol: amtB
gene_biotype: protein_coding
description:
  Ammonia channel precursor (Ammonia transporter); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_0857
symbol: glnK
gene_biotype: protein_coding
description:
  Nitrogen regulatory protein P-II 2; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.


ensembl_gene_id: MEALZ_0860
symbol: glnA
gene_biotype: protein_coding
description:
  Glutamine synthetase (Glutamate--ammonia ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0861
symbol: glnL
gene_biotype: protein_coding
description:
  Nitrogen regulation protein NR(II); Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_0862
symbol: glnG
gene_biotype: protein_coding
description:
  Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: MEALZ_0863
symbol: tkt2
gene_biotype: protein_coding
description:
  Transketolase domain protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0864
symbol: CCE22558.1
gene_biotype: protein_coding
description:
  Uncharacterized transporter HI_0895; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MEALZ_0867
symbol: CCE22561.1
gene_biotype: protein_coding
description:
  Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) (fragment).


ensembl_gene_id: MEALZ_0869
symbol: CCE22563.1
gene_biotype: protein_coding
description:
  Putative Multi-sensor signal transduction histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0874
symbol: CCE22568.1
gene_biotype: protein_coding
description:
  Zinc-binding dehydrogenase superfamily (quinone oxidoreductase, NADPH dependent); Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_0875
symbol: sseA
gene_biotype: protein_coding
description:
  Putative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0876
symbol: nadE
gene_biotype: protein_coding
description:
  Glutamine-dependent NAD(+) synthetase (NAD(+) synthase [glutamine-hydrolyzing]) (NadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: MEALZ_0878
symbol: miaB
gene_biotype: protein_coding
description:
  Putative tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: MEALZ_0879
symbol: phoL
gene_biotype: protein_coding
description:
  Phosphate starvation-inducible protein; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_0880
symbol: ybeY
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: MEALZ_0888
symbol: aspC
gene_biotype: protein_coding
description:
  Aspartate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0889
symbol: uvrB
gene_biotype: protein_coding
description:
  UvrABC system protein B (Protein uvrB) (Excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...]


ensembl_gene_id: MEALZ_0892
symbol: CCE22586.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0893
symbol: CCE22587.1
gene_biotype: protein_coding
description:
  Putative heme oxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0895
symbol: thrS
gene_biotype: protein_coding
description:
  Threonyl-tRNA synthetase (Threonine--tRNA ligase) (ThrRS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: MEALZ_0896
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: MEALZ_0897
symbol: rpmI
gene_biotype: protein_coding
description:
  50S ribosomal protein L35; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: MEALZ_0898
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: MEALZ_0899
symbol: pheS
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase alpha chain (Phenylalanine--tRNA ligase alpha chain) (PheRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: MEALZ_0900
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain) (PheRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: MEALZ_0901
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: MEALZ_0907
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: MEALZ_0908
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: MEALZ_0910
symbol: fliI
gene_biotype: protein_coding
description:
  Flagellum-specific ATP synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_0917
symbol: msrP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...]


ensembl_gene_id: MEALZ_0922
symbol: CCE22616.1
gene_biotype: protein_coding
description:
  Putative ATP-binding region, ATPase-like:Histidine kinase A, N-terminal; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0923
symbol: CCE22617.1
gene_biotype: protein_coding
description:
  Type II secretion system protein E:Response regulator receiver:General secretory system II, protein E, N-terminal.


ensembl_gene_id: MEALZ_0928
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: MEALZ_0930
symbol: CCE22624.1
gene_biotype: protein_coding
description:
  Putative Fe-S oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0931
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation factor rimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: MEALZ_0932
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation protein nusA (N utilization substance protein A) (L factor); Participates in both transcription termination and antitermination.


ensembl_gene_id: MEALZ_0933
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: MEALZ_0934
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: MEALZ_0935
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: MEALZ_0936
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: MEALZ_0937
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase (Polynucleotide phosphorylase) (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: MEALZ_0945
symbol: CCE22639.1
gene_biotype: protein_coding
description:
  Cobalbumin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: MEALZ_0946
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: MEALZ_0948
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: MEALZ_0950
symbol: CCE22644.1
gene_biotype: protein_coding
description:
  Putative antioxidant peroxiredoxin-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0953
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: MEALZ_0954
symbol: bluB
gene_biotype: protein_coding
description:
  5,6-dimethylbenzimidazole synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0955
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: MEALZ_0956
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: MEALZ_0957
symbol: CCE22651.1
gene_biotype: protein_coding
description:
  Putative threonine-phosphate decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0958
symbol: CCE22652.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0961
symbol: CCE22655.1
gene_biotype: protein_coding
description:
  Maltose alpha-D-glucosyltransferase (TreS-related); Function of homologous gene experimentally demonstrated in an other organism; putative enzyme.


ensembl_gene_id: MEALZ_0962
symbol: CCE22656.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative oxidoreductase; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_0966
symbol: CCE22660.1
gene_biotype: protein_coding
description:
  Putative Type I secretion outer membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_0981
symbol: CCE22675.1
gene_biotype: protein_coding
description:
  Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_0987
symbol: CCE22681.1
gene_biotype: protein_coding
description:
  Flagella basal body P-ring formation protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: MEALZ_0989
symbol: cheR
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: MEALZ_0990
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein flgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: MEALZ_0991
symbol: flgC
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgC (Putative proximal rod protein); Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: MEALZ_0992
symbol: CCE22686.1
gene_biotype: protein_coding
description:
  Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: MEALZ_0994
symbol: flgF
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgF (Putative proximal rod protein); Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: MEALZ_0995
symbol: flgG
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgG (Distal rod protein); Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: MEALZ_0996
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: MEALZ_0997
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein precursor (Basal body P-ring protein); Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: MEALZ_1000
symbol: CCE22694.1
gene_biotype: protein_coding
description:
  Putative Flagellin, N-terminus; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1004
symbol: rlmL
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: MEALZ_1006
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: MEALZ_1010
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase (decarboxylase), glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: MEALZ_1011
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage complex protein T, aminomethyltransferase, tetrahydrofolate-dependent; Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_1013
symbol: CCE22707.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1018
symbol: rsgA
gene_biotype: protein_coding
description:
  Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: MEALZ_1019
symbol: CCE22713.1
gene_biotype: protein_coding
description:
  Putative peptidase M48; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1020
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: MEALZ_1021
symbol: crcB
gene_biotype: protein_coding
description:
  Protein CrcB homolog; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: MEALZ_1023
symbol: serS
gene_biotype: protein_coding
description:
  Serine tRNA synthetase (Serine--tRNA ligase) (SerRS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: MEALZ_1024
symbol: CCE22718.1
gene_biotype: protein_coding
description:
  Putative ABC-type tungstate transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1025
symbol: CCE22719.1
gene_biotype: protein_coding
description:
  Putative methyltransferase CheR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1027
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: MEALZ_1031
symbol: serA
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: MEALZ_1034
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: MEALZ_1035
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: MEALZ_1036
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: MEALZ_1037
symbol: CCE22731.1
gene_biotype: protein_coding
description:
  Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1038
symbol: tolQ
gene_biotype: protein_coding
description:
  Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: MEALZ_1039
symbol: tolR
gene_biotype: protein_coding
description:
  Biopolymer transport protein ExbD/TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: MEALZ_1041
symbol: tolB
gene_biotype: protein_coding
description:
  Protein TolB precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: MEALZ_1042
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: MEALZ_1043
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: MEALZ_1044
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: MEALZ_1045
symbol: queC
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: MEALZ_1048
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.


ensembl_gene_id: MEALZ_1056
symbol: CCE22750.1
gene_biotype: protein_coding
description:
  Putative Fimbrial protein pilin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1063
symbol: CCE22757.1
gene_biotype: protein_coding
description:
  RelE-like toxin, toxin-antitoxin system; Function of strongly homologous gene; extrachromosomal origin.


ensembl_gene_id: MEALZ_1071
symbol: umuC
gene_biotype: protein_coding
description:
  Component of DNA polymerase V, subunit C; Function of strongly homologous gene; enzyme; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: MEALZ_1072
symbol: umuD
gene_biotype: protein_coding
description:
  Component of DNA polymerase V, subunit D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S24 family.


ensembl_gene_id: MEALZ_1078
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: MEALZ_1082
symbol: CCE22774.1
gene_biotype: protein_coding
description:
  Putative resolvase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1115
symbol: CCE22807.1
gene_biotype: protein_coding
description:
  Putative GTP-binding protein HSR1-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1118
symbol: CCE22809.1
gene_biotype: protein_coding
description:
  Putative Ggdef family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1124
symbol: ksgA
gene_biotype: protein_coding
description:
  S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: MEALZ_1125
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase (4-(phosphohydroxy)-L-threonine dehydrogenase); Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: MEALZ_1129
symbol: CCE22820.1
gene_biotype: protein_coding
description:
  Putative chaperone heat-shock protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1130
symbol: CCE22821.1
gene_biotype: protein_coding
description:
  Putative virion core protein (Lumpy skin disease virus)-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1132
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: MEALZ_1133
symbol: CCE22824.1
gene_biotype: protein_coding
description:
  Putative Competence-damaged protein CinA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process; Belongs to the CinA family.


ensembl_gene_id: MEALZ_1140
symbol: gltX
gene_biotype: protein_coding
description:
  Glutamyl-tRNA synthetase (Glutamate--tRNA ligase) (GluRS); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: MEALZ_1141
symbol: bfr
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: MEALZ_1143
symbol: CCE22834.1
gene_biotype: protein_coding
description:
  Putative lysine decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the LOG family.


ensembl_gene_id: MEALZ_1145
symbol: CCE22836.1
gene_biotype: protein_coding
description:
  Putative permease of the major facilitator superfamily (MFS); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1147
symbol: CCE22838.1
gene_biotype: protein_coding
description:
  Putative Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: MEALZ_1154
symbol: CCE22845.1
gene_biotype: protein_coding
description:
  Putative anion transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1156
symbol: CCE22846.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1163
symbol: CCE22853.1
gene_biotype: protein_coding
description:
  Putative suppressor for copper-sensitivity D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1171
symbol: qoxA
gene_biotype: protein_coding
description:
  Heme-copper quinol oxidase, subunit I; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: MEALZ_1173
symbol: CCE22863.1
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase assembly factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_1177
symbol: CCE22867.1
gene_biotype: protein_coding
description:
  Putative thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1181
symbol: CCE22871.1
gene_biotype: protein_coding
description:
  Putative SAM-dependent methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1182
symbol: CCE22872.1
gene_biotype: protein_coding
description:
  Putative DNA/RNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S24 family.


ensembl_gene_id: MEALZ_1212
symbol: CCE22902.1
gene_biotype: protein_coding
description:
  Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1216
symbol: sdaB
gene_biotype: protein_coding
description:
  L-serine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: MEALZ_1217
symbol: comL
gene_biotype: protein_coding
description:
  Competence lipoprotein ComL precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: MEALZ_1218
symbol: rluD
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: MEALZ_1219
symbol: CCE22909.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: MEALZ_1221
symbol: pgm
gene_biotype: protein_coding
description:
  Phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1225
symbol: rdgC
gene_biotype: protein_coding
description:
  Recombination-associated protein rdgC; May be involved in recombination; Belongs to the RdgC family.


ensembl_gene_id: MEALZ_1229
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: MEALZ_1232
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: MEALZ_1234
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: MEALZ_1235
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: MEALZ_1237
symbol: CCE22927.1
gene_biotype: protein_coding
description:
  Putative TRAP dicarboxylate transporter, DctM subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1238
symbol: CCE22928.1
gene_biotype: protein_coding
description:
  Putative TRAP C4-dicarboxylate transport system, DctQ subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1247
symbol: CCE22937.1
gene_biotype: protein_coding
description:
  Putative Fimbrial protein pilin similar to FimU; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1255
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase (SDAP); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: MEALZ_1256
symbol: CCE22946.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative ArsC family; Homologs of previously reported genes of unknown function; Belongs to the ArsC family.


ensembl_gene_id: MEALZ_1259
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: MEALZ_1260
symbol: dapC
gene_biotype: protein_coding
description:
  N-succinyl-L,L-diaminopimelate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1263
symbol: fhcA
gene_biotype: protein_coding
description:
  Formyltransferase/hydrolase complex Fhc subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1269
symbol: ffsA
gene_biotype: protein_coding
description:
  Formylmethanofuran--tetrahydromethanopterin formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.


ensembl_gene_id: MEALZ_1275
symbol: nirB
gene_biotype: protein_coding
description:
  Nitrite reductase [NAD(P)H] large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: MEALZ_1278
symbol: cynS
gene_biotype: protein_coding
description:
  Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: MEALZ_1279
symbol: CCE22968.1
gene_biotype: protein_coding
description:
  Putative dual serine/threonine-protein kinase/phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1280
symbol: CCE22969.1
gene_biotype: protein_coding
description:
  Putative formate/nitrate transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1285
symbol: CCE22974.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1292
symbol: CCE22981.1
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase, CbaD subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1293
symbol: CCE22982.1
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase, subunit II (cbaB); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1294
symbol: CCE22983.1
gene_biotype: protein_coding
description:
  Putative Cytochrome c oxidase, subunit I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1296
symbol: thiF
gene_biotype: protein_coding
description:
  Adenylyltransferase thiF; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1297
symbol: groS
gene_biotype: protein_coding
description:
  10 kDa chaperonin (Protein Cpn10) (groES protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: MEALZ_1298
symbol: groL
gene_biotype: protein_coding
description:
  60 kDa chaperonin (Protein Cpn60) (groEL protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: MEALZ_1304
symbol: hoxH
gene_biotype: protein_coding
description:
  NAD-reducing hydrogenase hoxS subunit beta; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: MEALZ_1312
symbol: erg
gene_biotype: protein_coding
description:
  Delta(14)-sterol reductase; Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta- 8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Complements the deletion of the Delta(14)-sterol reductase gene ERG24 in yeast; Belongs to the ERG4/ERG24 family.


ensembl_gene_id: MEALZ_1315
symbol: CCE23004.1
gene_biotype: protein_coding
description:
  Putative methylthiotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1317
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdopterin molybdenumtransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: MEALZ_1320
symbol: CCE23009.1
gene_biotype: protein_coding
description:
  Putative sulfur oxidation protein SoxY; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1323
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: MEALZ_1329
symbol: CCE23018.1
gene_biotype: protein_coding
description:
  Putative sulfate transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1330
symbol: CCE23019.1
gene_biotype: protein_coding
description:
  Putative universal stress protein UspA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_1333
symbol: CCE23022.1
gene_biotype: protein_coding
description:
  Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: MEALZ_1334
symbol: CCE23023.1
gene_biotype: protein_coding
description:
  Putative NAD-dependent epimerase/dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1337
symbol: CCE23026.1
gene_biotype: protein_coding
description:
  Putative phosphohistidine phosphatase, SixA (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1338
symbol: pstS1a
gene_biotype: protein_coding
description:
  ABC-type phosphate transport system, periplasmic component; Function of strongly homologous gene; transporter.


ensembl_gene_id: MEALZ_1339
symbol: CCE23028.1
gene_biotype: protein_coding
description:
  Putative ABC-type phosphate transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1340
symbol: CCE23029.1
gene_biotype: protein_coding
description:
  Putative ABC-type phosphate transport system, auxiliary and permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1341
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate import ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: MEALZ_1343
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: MEALZ_1344
symbol: tag
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1350
symbol: CCE23039.1
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.


ensembl_gene_id: MEALZ_1351
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: MEALZ_1352
symbol: cas2
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: MEALZ_1356
symbol: purN
gene_biotype: protein_coding
description:
  Putative phosphoribosylglycinamide formyltransferase/formyltetrahydrofolate deformylase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: MEALZ_1357
symbol: pdhD
gene_biotype: protein_coding
description:
  Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1358
symbol: pdhB
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: MEALZ_1359
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: MEALZ_1360
symbol: gltA
gene_biotype: protein_coding
description:
  Citrate synthase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.


ensembl_gene_id: MEALZ_1362
symbol: eda
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxy-phosphogluconate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1363
symbol: edd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: MEALZ_1364
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit (AIR carboxylase) (AIRC); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: MEALZ_1365
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: MEALZ_1371
symbol: mtdB
gene_biotype: protein_coding
description:
  NAD(P)-dependent methylene tetrahydromethanopterin dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1374
symbol: CCE23063.1
gene_biotype: protein_coding
description:
  Orn/DAP/Arg decarboxylase 2; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.


ensembl_gene_id: MEALZ_1378
symbol: mrcB
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B [Includes: Penicillin-insensitive transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: MEALZ_1396
symbol: CCE23084.1
gene_biotype: protein_coding
description:
  Putative di-haem enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1399
symbol: CCE23087.1
gene_biotype: protein_coding
description:
  Protein of unknown function; No homology to any previously reported sequences; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: MEALZ_1409
symbol: rnr
gene_biotype: protein_coding
description:
  RNase R, 3'-5' exoribonuclease; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: MEALZ_1410
symbol: rlmB
gene_biotype: protein_coding
description:
  23S rRNA (guanosine-2'-O-)-methyltransferase RlmB (23S rRNA Gm2251 2'-O-methyltransferase); Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: MEALZ_1416
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase 4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: MEALZ_1417
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: MEALZ_1425
symbol: CCE23113.1
gene_biotype: protein_coding
description:
  Putative Polysaccharide chain length determinant protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1433
symbol: xdhC
gene_biotype: protein_coding
description:
  Putative xanthine dehydrogenase accessory factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_1437
symbol: xdhA
gene_biotype: protein_coding
description:
  Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit; Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_1438
symbol: ade
gene_biotype: protein_coding
description:
  Adenine deaminase; Function of strongly homologous gene; enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: MEALZ_1440
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: MEALZ_1442
symbol: CCE23130.1
gene_biotype: protein_coding
description:
  Putative 2Fe-2S ferredoxin-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: MEALZ_1444
symbol: CCE23132.1
gene_biotype: protein_coding
description:
  Putative methyltransferase with corrinoid-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the uroporphyrinogen decarboxylase family.


ensembl_gene_id: MEALZ_1446
symbol: CCE23134.1
gene_biotype: protein_coding
description:
  Putative two-component sensor protein histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1447
symbol: CCE23135.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1448
symbol: bioA
gene_biotype: protein_coding
description:
  7,8-diaminopelargonic acid synthase, PLP-dependent; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: MEALZ_1450
symbol: degP
gene_biotype: protein_coding
description:
  Putative serine protease do-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase S1C family.


ensembl_gene_id: MEALZ_1452
symbol: CCE23140.1
gene_biotype: protein_coding
description:
  Conserved membrane protein precursor of unknown function, DUF395, YeeE/YedE; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_1453
symbol: CCE23141.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative sulfite oxidase; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_1459
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: MEALZ_1460
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: MEALZ_1461
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family.


ensembl_gene_id: MEALZ_1462
symbol: eno
gene_biotype: protein_coding
description:
  Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: MEALZ_1463
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein ftsB homolog; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: MEALZ_1464
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: MEALZ_1465
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS) (MECDP-synthase); Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: MEALZ_1466
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: MEALZ_1467
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase 2; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: MEALZ_1469
symbol: surE
gene_biotype: protein_coding
description:
  5'-nucleotidase SurE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: MEALZ_1470
symbol: pcm-2
gene_biotype: protein_coding
description:
  Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: MEALZ_1472
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: MEALZ_1474
symbol: CCE23162.1
gene_biotype: protein_coding
description:
  Putative ferredoxin 2fe-2s protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1480
symbol: uvrA
gene_biotype: protein_coding
description:
  UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: MEALZ_1482
symbol: trpF
gene_biotype: protein_coding
description:
  N-(5'-phosphoribosyl)anthranilate isomerase (PRAI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family.


ensembl_gene_id: MEALZ_1483
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: MEALZ_1484
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: MEALZ_1485
symbol: accD
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: MEALZ_1486
symbol: folC
gene_biotype: protein_coding
description:
  FolC bifunctional protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: MEALZ_1487
symbol: CCE23175.1
gene_biotype: protein_coding
description:
  Putative Sporulation domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1489
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: MEALZ_1490
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: MEALZ_1491
symbol: CCE23179.1
gene_biotype: protein_coding
description:
  Conserved MxaD-like protein precursor of unknown function; Homologs of previously reported genes of unknown function; putative factor.


ensembl_gene_id: MEALZ_1496
symbol: ubiG
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: MEALZ_1497
symbol: mtaD
gene_biotype: protein_coding
description:
  5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.


ensembl_gene_id: MEALZ_1498
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: MEALZ_1502
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: MEALZ_1510
symbol: cysG
gene_biotype: protein_coding
description:
  Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: MEALZ_1517
symbol: cbiD
gene_biotype: protein_coding
description:
  Putative cobalt-precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: MEALZ_1520
symbol: cobM
gene_biotype: protein_coding
description:
  Precorrin-4 C(11)-methyltransferase (Precorrin-3 methylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: MEALZ_1521
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: MEALZ_1525
symbol: CCE23213.1
gene_biotype: protein_coding
description:
  Putative non-ribosomal peptide synthetase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1526
symbol: CCE23214.1
gene_biotype: protein_coding
description:
  Putative non-ribosomal peptide synthetase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: MEALZ_1531
symbol: CCE23219.1
gene_biotype: protein_coding
description:
  Putative 4'-phosphopantetheinyl transferase HetI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: MEALZ_1536
symbol: CCE23224.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: MEALZ_1543
symbol: CCE23231.1
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MEALZ_1545
symbol: CCE23233.1
gene_biotype: protein_coding
description:
  Putative TonB-dependent membrane protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: MEALZ_1546
symbol: CCE23234.1
gene_biotype: protein_coding
description:
  Putative biopolymer transport ExbB protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1551
symbol: prmB
gene_biotype: protein_coding
description:
  Putative Site-specific DNA-methyltransferase (adenine-specific); Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: MEALZ_1552
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: MEALZ_1554
symbol: CCE23242.1
gene_biotype: protein_coding
description:
  Putative biopolymer transport protein ExbB-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1556
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4' kinase (lipid A 4'kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: MEALZ_1557
symbol: CCE23245.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0434 family.


ensembl_gene_id: MEALZ_1558
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: MEALZ_1560
symbol: CCE23247.1
gene_biotype: protein_coding
description:
  Putative PLP-dependent aminotransferase (transaminase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1561
symbol: hom
gene_biotype: protein_coding
description:
  Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1562
symbol: thrC
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: MEALZ_1563
symbol: recJ
gene_biotype: protein_coding
description:
  Single-stranded-DNA-specific exonuclease RecJ; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1564
symbol: CCE23251.1
gene_biotype: protein_coding
description:
  Putative metal dependent phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1565
symbol: nnrD
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the r [...]


ensembl_gene_id: MEALZ_1566
symbol: CCE23253.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative ATPase; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_1567
symbol: amiC
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1568
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: MEALZ_1569
symbol: miaA
gene_biotype: protein_coding
description:
  Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: MEALZ_1571
symbol: rbgA
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: MEALZ_1576
symbol: gabD
gene_biotype: protein_coding
description:
  Putative succinate-semialdehyde dehydrogenase [NADP+]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1579
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: MEALZ_1580
symbol: sucA
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1589
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor rpoS (Sigma-38); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: MEALZ_1590
symbol: CCE23277.1
gene_biotype: protein_coding
description:
  Putative nitrilase (nthA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1591
symbol: CCE23278.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative N-acetyltransferase; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_1605
symbol: CCE23292.1
gene_biotype: protein_coding
description:
  Putative polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1610
symbol: CCE23297.1
gene_biotype: protein_coding
description:
  Putative transposase-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1612
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: MEALZ_1616
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: MEALZ_1618
symbol: queF
gene_biotype: protein_coding
description:
  NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: MEALZ_1619
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: MEALZ_1620
symbol: CCE23307.1
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.


ensembl_gene_id: MEALZ_1622
symbol: CCE23309.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the SOS response-associated peptidase family.


ensembl_gene_id: MEALZ_1625
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase (Polyphosphoric acid kinase) (ATP-polyphosphate phosphotransferase); Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: MEALZ_1627
symbol: sul
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: MEALZ_1629
symbol: CCE23316.1
gene_biotype: protein_coding
description:
  Conserved protein (Orf20) involved in biosynthesis of tetrahydromethanopterin; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1630
symbol: CCE23317.1
gene_biotype: protein_coding
description:
  Conserved protein (Orf19) involved in biosynthesis of tetrahydromethanopterin; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1631
symbol: CCE23318.1
gene_biotype: protein_coding
description:
  Conserved protein (Orf22) involved in biosynthesis of tetrahydromethanopterin; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1632
symbol: CCE23319.1
gene_biotype: protein_coding
description:
  Sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: MEALZ_1633
symbol: pgm3
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-independent phosphoglycerate mutase (iPGM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family.


ensembl_gene_id: MEALZ_1634
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: MEALZ_1657
symbol: atpA-2
gene_biotype: protein_coding
description:
  V-type ATP synthase alpha chain 1; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: MEALZ_1659
symbol: CCE23346.1
gene_biotype: protein_coding
description:
  Putative Protein-tyrosine-phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: MEALZ_1662
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: MEALZ_1668
symbol: CCE23355.1
gene_biotype: protein_coding
description:
  Putative multicopper oxidase CumA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1672
symbol: CCE23359.1
gene_biotype: protein_coding
description:
  Putative CoA-ligase homologue involved in photoreceptor activation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1673
symbol: CCE23360.1
gene_biotype: protein_coding
description:
  Putative signalling protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.


ensembl_gene_id: MEALZ_1676
symbol: glcF-2
gene_biotype: protein_coding
description:
  Glycolate oxidase, iron-sulfur subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: MEALZ_1677
symbol: glcE
gene_biotype: protein_coding
description:
  Glycolate oxidase, FAD binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1678
symbol: CCE23365.1
gene_biotype: protein_coding
description:
  Glycolate oxidase (GlcD-like), FAD-linked subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1681
symbol: CCE23368.1
gene_biotype: protein_coding
description:
  Putative outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.


ensembl_gene_id: MEALZ_1682
symbol: CCE23369.1
gene_biotype: protein_coding
description:
  Putative RND transporter translocase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1691
symbol: amy
gene_biotype: protein_coding
description:
  D-Glucan glucanohydrolase (alpha amylase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1692
symbol: gntK
gene_biotype: protein_coding
description:
  Gluconokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1693
symbol: gnl
gene_biotype: protein_coding
description:
  Gluconolactonase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1696
symbol: CCE23383.1
gene_biotype: protein_coding
description:
  Putative RecA-superfamily ATPase implicated in signal transduction; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1697
symbol: CCE23384.1
gene_biotype: protein_coding
description:
  Putative thiol disulfide isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1699
symbol: gdhI
gene_biotype: protein_coding
description:
  Glucose 1-dehydrogenase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1701
symbol: mprA
gene_biotype: protein_coding
description:
  Two-component signal transduction system response regulator; Function of strongly homologous gene; regulator.


ensembl_gene_id: MEALZ_1702
symbol: CCE23389.1
gene_biotype: protein_coding
description:
  Two-component signal transduction system response, histidine kinase sensor; Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_1706
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: MEALZ_1710
symbol: yjeS
gene_biotype: protein_coding
description:
  Putative electron transport protein yjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: MEALZ_1715
symbol: CCE23402.1
gene_biotype: protein_coding
description:
  Putative Flagellar hook-length control protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1722
symbol: grxC
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: MEALZ_1723
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-5-phosphate 4-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1724
symbol: bfr-2
gene_biotype: protein_coding
description:
  Bacterioferritin (BFR) (Cytochrome b-557.5); Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: MEALZ_1725
symbol: CCE23412.1
gene_biotype: protein_coding
description:
  Putative bacterioferritin-associated ferredoxin Bfd; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: MEALZ_1726
symbol: CCE23413.1
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: MEALZ_1736
symbol: CCE23422.1
gene_biotype: protein_coding
description:
  Putative integral membrane sensor hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.


ensembl_gene_id: MEALZ_1744
symbol: fmdE
gene_biotype: protein_coding
description:
  ABC transporter permease component; Function of strongly homologous gene; transporter; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MEALZ_1749
symbol: CCE23435.1
gene_biotype: protein_coding
description:
  Putative formamidase regulatory protein FmdB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_1760
symbol: CCE23446.1
gene_biotype: protein_coding
description:
  Urea transport system substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1764
symbol: CCE23450.1
gene_biotype: protein_coding
description:
  Urea transport system permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MEALZ_1765
symbol: CCE23451.1
gene_biotype: protein_coding
description:
  Putative Amino acid or sugar ABC transport system, permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MEALZ_1766
symbol: CCE23452.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1767
symbol: CCE23453.1
gene_biotype: protein_coding
description:
  Urea transport system ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1769
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: MEALZ_1772
symbol: ureC
gene_biotype: protein_coding
description:
  Urease alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1773
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein ureE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: MEALZ_1774
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: MEALZ_1775
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: MEALZ_1776
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: MEALZ_1778
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: MEALZ_1784
symbol: CCE23470.1
gene_biotype: protein_coding
description:
  Putative Mitogen-activated protein kinase kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1792
symbol: rppH
gene_biotype: protein_coding
description:
  Putative (di)nucleoside polyphosphate hydrolase NudH-like; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: MEALZ_1793
symbol: icc
gene_biotype: protein_coding
description:
  Protein icc homolog; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: MEALZ_1795
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase (DAD) (2,3-dihydroxy acid hydrolyase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family.


ensembl_gene_id: MEALZ_1797
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase (OTCase); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: MEALZ_1798
symbol: argD
gene_biotype: protein_coding
description:
  Succinylornithine transaminase, also has acetylornitine transaminase activity, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: MEALZ_1800
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: MEALZ_1804
symbol: carA
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase small chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family.


ensembl_gene_id: MEALZ_1805
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl phosphate synthase, large subunit (Carbamoyl-phosphate synthetase ammonia chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.


ensembl_gene_id: MEALZ_1806
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor greA (Transcript cleavage factor greA); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: MEALZ_1808
symbol: ftsJ
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: MEALZ_1809
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: MEALZ_1810
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: MEALZ_1811
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase (TIM) (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: MEALZ_1812
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: MEALZ_1819
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase 2; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: MEALZ_1821
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: MEALZ_1823
symbol: CCE23509.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase, oxoglutarate-Fe(II)-dependent oxygenase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1825
symbol: rlmG
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase G; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: MEALZ_1827
symbol: fumA
gene_biotype: protein_coding
description:
  Putative fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: MEALZ_1834
symbol: CCE23520.1
gene_biotype: protein_coding
description:
  Putative transcriptional coactivator/pterin dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1836
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase (Pyruvate, water dikinase) (PEP synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: MEALZ_1837
symbol: selO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: MEALZ_1839
symbol: CCE23525.1
gene_biotype: protein_coding
description:
  Putative stress-induced morphogen BolA protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype; Belongs to the BolA/IbaG family.


ensembl_gene_id: MEALZ_1841
symbol: ispZ
gene_biotype: protein_coding
description:
  Intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: MEALZ_1845
symbol: proA-2
gene_biotype: protein_coding
description:
  Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: MEALZ_1846
symbol: nadD
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: MEALZ_1847
symbol: rsfS
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: MEALZ_1850
symbol: vapC
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: MEALZ_1853
symbol: arsC
gene_biotype: protein_coding
description:
  Arsenate reductase / phosphotyrosine protein phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: MEALZ_1860
symbol: pykA
gene_biotype: protein_coding
description:
  Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1862
symbol: pstC
gene_biotype: protein_coding
description:
  ABC phosphate transport system, permease component; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: MEALZ_1863
symbol: pstA
gene_biotype: protein_coding
description:
  ABC phosphate transport system, permease component; Function of strongly homologous gene; transporter.


ensembl_gene_id: MEALZ_1864
symbol: pstB-2
gene_biotype: protein_coding
description:
  Phosphate import ABC transporter, ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: MEALZ_1868
symbol: CCE23554.1
gene_biotype: protein_coding
description:
  Putative cytoplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1875
symbol: recN
gene_biotype: protein_coding
description:
  DNA repair protein RecN (Recombination protein N); May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: MEALZ_1876
symbol: nadK
gene_biotype: protein_coding
description:
  NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: MEALZ_1877
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: MEALZ_1878
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: MEALZ_1880
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent inte [...]


ensembl_gene_id: MEALZ_1881
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: MEALZ_1882
symbol: fdh1A
gene_biotype: protein_coding
description:
  Tungsten-containing NAD-dependent formate dehydrogenase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: MEALZ_1883
symbol: fdh1B
gene_biotype: protein_coding
description:
  Tungsten-containing NAD-dependent formate dehydrogenase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1885
symbol: CCE23571.1
gene_biotype: protein_coding
description:
  Putative metallo-hydrolase/oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1890
symbol: mobA
gene_biotype: protein_coding
description:
  Putative molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: MEALZ_1891
symbol: fdhD
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: MEALZ_1894
symbol: CCE23580.1
gene_biotype: protein_coding
description:
  Putative L-sorbosone dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1897
symbol: vipA
gene_biotype: protein_coding
description:
  Vi polysaccharide biosynthesis protein vipA/tviB; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: MEALZ_1906
symbol: CCE23592.1
gene_biotype: protein_coding
description:
  Putative Type IV pilus assembly PilZ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1908
symbol: CCE23594.1
gene_biotype: protein_coding
description:
  Putative Sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1911
symbol: proS
gene_biotype: protein_coding
description:
  Prolyl-tRNA synthetase (Proline--tRNA ligase) (ProRS) (Global RNA synthesis factor); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other a [...]


ensembl_gene_id: MEALZ_1912
symbol: hpsi2
gene_biotype: protein_coding
description:
  Hexulose-6-phosphate synthase and isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_1913
symbol: CCE23599.1
gene_biotype: protein_coding
description:
  Putative Permease of the major facilitator superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_1914
symbol: ssb
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein (SSB) (Helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: MEALZ_1918
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional protein BirA [Includes: Biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: MEALZ_1919
symbol: coaX
gene_biotype: protein_coding
description:
  Transcriptional activator, Baf family (modular protein); Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: MEALZ_1925
symbol: CCE23611.1
gene_biotype: protein_coding
description:
  Putative FHA domain containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1927
symbol: ompA
gene_biotype: protein_coding
description:
  Putative outer membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1929
symbol: CCE23615.1
gene_biotype: protein_coding
description:
  Putative phosphoprotein phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1930
symbol: CCE23616.1
gene_biotype: protein_coding
description:
  Putative Type VI secretion-associated protein, ImpA family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1931
symbol: sciH
gene_biotype: protein_coding
description:
  Putative cytoplasmic protein,SciH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1934
symbol: sciE
gene_biotype: protein_coding
description:
  Putative cytoplasmic protein,sciE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_1956
symbol: CCE23642.1
gene_biotype: protein_coding
description:
  Putative Non-specific protein-tyrosine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1960
symbol: rubA
gene_biotype: protein_coding
description:
  Rubredoxin (Rd); Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: MEALZ_1961
symbol: hypA
gene_biotype: protein_coding
description:
  Putative nickel-iron hydrogenase, nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: MEALZ_1963
symbol: hupE
gene_biotype: protein_coding
description:
  Nickel-iron hydrogenase, accessory protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MEALZ_1964
symbol: hypE
gene_biotype: protein_coding
description:
  Nickel-iron hydrogenase, metallocenter assembly protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MEALZ_1970
symbol: hypF
gene_biotype: protein_coding
description:
  Nickel-iron hydrogenase, carbamoyltransferase maturation factor; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: MEALZ_1971
symbol: hypD
gene_biotype: protein_coding
description:
  Nickel-iron hydrogenase, metal-binding maturation protein; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HypD family.


ensembl_gene_id: MEALZ_1972
symbol: hypB
gene_biotype: protein_coding
description:
  Nickel-iron hydrogenase, nickel incorporation protein; Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_1973
symbol: CCE23659.1
gene_biotype: protein_coding
description:
  Putative lactoylglutathione lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1978
symbol: ppnP
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: MEALZ_1982
symbol: CCE23668.1
gene_biotype: protein_coding
description:
  Putative rRNA methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1987
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: MEALZ_1988
symbol: CCE23674.1
gene_biotype: protein_coding
description:
  Sodium:neurotransmitter symporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: MEALZ_1989
symbol: CCE23675.1
gene_biotype: protein_coding
description:
  Putative cyclase/dehydrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_1991
symbol: bamE
gene_biotype: protein_coding
description:
  SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: MEALZ_1992
symbol: fur
gene_biotype: protein_coding
description:
  Ferric uptake regulation protein (Ferric uptake regulator); Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the Fur family.


ensembl_gene_id: MEALZ_1993
symbol: lolC
gene_biotype: protein_coding
description:
  Lipoprotein-releasing system transmembrane protein LolC; Function of strongly homologous gene; transporter.


ensembl_gene_id: MEALZ_1994
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: MEALZ_2001
symbol: sufC
gene_biotype: protein_coding
description:
  ABC transporter, ATPase; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_2004
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: MEALZ_2006
symbol: rsmJ
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: MEALZ_2008
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: MEALZ_2010
symbol: lysS
gene_biotype: protein_coding
description:
  Lysyl-tRNA synthetase (Lysine--tRNA ligase) (LysRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: MEALZ_2015
symbol: CCE23701.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2019
symbol: CCE23705.1
gene_biotype: protein_coding
description:
  Putative Mg-dependent DNase, TatD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2022
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase (dTMP kinase); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: MEALZ_2023
symbol: mltG
gene_biotype: protein_coding
description:
  Putative Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: MEALZ_2025
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: MEALZ_2027
symbol: fabG-2
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase); Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MEALZ_2028
symbol: fabD
gene_biotype: protein_coding
description:
  malonyl-CoA-[acyl-carrier-protein] transacylase (MCT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2029
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: MEALZ_2030
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: MEALZ_2031
symbol: rpmF
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: MEALZ_2033
symbol: CCE23719.1
gene_biotype: protein_coding
description:
  Putative septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: MEALZ_2039
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: MEALZ_2041
symbol: CCE23727.1
gene_biotype: protein_coding
description:
  Putative transmembrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2049
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: MEALZ_2055
symbol: CCE23741.1
gene_biotype: protein_coding
description:
  Putative sensory transducer protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_2059
symbol: CCE23745.1
gene_biotype: protein_coding
description:
  Putative two-component sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_2060
symbol: CCE23746.1
gene_biotype: protein_coding
description:
  Putative response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_2067
symbol: MEALZ_2067
gene_biotype: protein_coding
description:
  Fragment of putative resolvase (part 1); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2070
symbol: CCE23756.1
gene_biotype: protein_coding
description:
  Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: MEALZ_2094
symbol: CCE23780.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative ATPase domain; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_2098
symbol: CCE23784.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, CopG family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2106
symbol: CCE23792.1
gene_biotype: protein_coding
description:
  DNA integration/recombination/inversion protein, site-specific recombinase, phage integrase family (fragment).


ensembl_gene_id: MEALZ_2118
symbol: CCE23804.1
gene_biotype: protein_coding
description:
  Putative serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2128
symbol: CCE23814.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative lytic transglycolase; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_2136
symbol: CCE23822.1
gene_biotype: protein_coding
description:
  Site-specific DNA recombinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2140
symbol: engD
gene_biotype: protein_coding
description:
  GTP-dependent nucleic acid-binding protein EngD; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: MEALZ_2142
symbol: CCE23828.1
gene_biotype: protein_coding
description:
  Conserved protein, putative folate-binding protein; Homologs of previously reported genes of unknown function; putative factor; Belongs to the GcvT family.


ensembl_gene_id: MEALZ_2144
symbol: CCE23830.1
gene_biotype: protein_coding
description:
  Putative cytochrome oxidase assembly protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_2145
symbol: cdd
gene_biotype: protein_coding
description:
  Cytosine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2147
symbol: CCE23833.1
gene_biotype: protein_coding
description:
  RND efflux transporter, MFP subunit; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MEALZ_2148
symbol: acrB
gene_biotype: protein_coding
description:
  Acriflavine resistance protein B; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_2163
symbol: CCE23849.1
gene_biotype: protein_coding
description:
  Putative reverse transcriptase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2173
symbol: CCE23859.1
gene_biotype: protein_coding
description:
  Putative Phage baseplate outer wedge protein (Acidic lysozyme); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2179
symbol: CCE23865.1
gene_biotype: protein_coding
description:
  Putative Phage tail tube protein gp19; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2184
symbol: CCE23870.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function, UPF0229 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0229 family.


ensembl_gene_id: MEALZ_2186
symbol: CCE23872.1
gene_biotype: protein_coding
description:
  Putative pirin-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the pirin family.


ensembl_gene_id: MEALZ_2192
symbol: CCE23878.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, Crp/Fnr family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2195
symbol: CCE23881.1
gene_biotype: protein_coding
description:
  Protein of unknown function; No homology to any previously reported sequences; Belongs to the UPF0149 family.


ensembl_gene_id: MEALZ_2199
symbol: CCE23885.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase, molybdenum cofactor binding subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.


ensembl_gene_id: MEALZ_2200
symbol: CCE23886.1
gene_biotype: protein_coding
description:
  Oxidoreductase, 2Fe-2S subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2201
symbol: CCE23887.1
gene_biotype: protein_coding
description:
  Putative enzyme for molybdopterin cofactor synthesis; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2202
symbol: CCE23888.1
gene_biotype: protein_coding
description:
  Putative dehydrogenase molybdenum attachment maturation factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_2203
symbol: CCE23889.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, Zn(II)-binding (Zur-related); Function of strongly homologous gene; regulator; Belongs to the Fur family.


ensembl_gene_id: MEALZ_2204
symbol: CCE23890.1
gene_biotype: protein_coding
description:
  Putative polyphosphate:AMP phosphotransferase; Homologs of previously reported genes of unknown function; putative enzyme.


ensembl_gene_id: MEALZ_2208
symbol: CCE23894.1
gene_biotype: protein_coding
description:
  Putative sodium/solute transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: MEALZ_2211
symbol: CCE23897.1
gene_biotype: protein_coding
description:
  Putative anti-sigma regulatory factor, serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2217
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: MEALZ_2218
symbol: CCE23904.1
gene_biotype: protein_coding
description:
  Putative malto-oligosyltrehalose trehalohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2225
symbol: CCE23911.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2227
symbol: CCE23913.1
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: MEALZ_2228
symbol: nqrF
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: MEALZ_2229
symbol: nqrE
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: MEALZ_2230
symbol: nqrD
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: MEALZ_2231
symbol: nqrC
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: MEALZ_2232
symbol: nqrB
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: MEALZ_2233
symbol: nqrA
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: MEALZ_2234
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: MEALZ_2235
symbol: aspS
gene_biotype: protein_coding
description:
  Aspartyl-tRNA synthetase (Aspartate--tRNA ligase) (AspRS); Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: MEALZ_2237
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase (DHOase); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.


ensembl_gene_id: MEALZ_2243
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: MEALZ_2246
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: MEALZ_2249
symbol: cysM
gene_biotype: protein_coding
description:
  Cysteine synthase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: MEALZ_2250
symbol: CCE23935.1
gene_biotype: protein_coding
description:
  Putative two-component hybrid sensor and regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2251
symbol: CCE23936.1
gene_biotype: protein_coding
description:
  Putative two-component sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2257
symbol: CCE23942.1
gene_biotype: protein_coding
description:
  Putative adenosylhomocysteinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2265
symbol: CCE23950.1
gene_biotype: protein_coding
description:
  Putative subtilisin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S8 family.


ensembl_gene_id: MEALZ_2271
symbol: CCE23955.1
gene_biotype: protein_coding
description:
  Putative Retinol dehydrogenase 13; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2278
symbol: CCE23960.1
gene_biotype: protein_coding
description:
  Putative Copper-exporting ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2279
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: MEALZ_2287
symbol: CCE23968.1
gene_biotype: protein_coding
description:
  Putative nitrate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: MEALZ_2288
symbol: CCE23969.1
gene_biotype: protein_coding
description:
  Putative Ribonuclease T(1); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2294
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: MEALZ_2296
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase (3-dehydroquinase) (Type II DHQase); Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: MEALZ_2297
symbol: accB
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: MEALZ_2298
symbol: accC
gene_biotype: protein_coding
description:
  Biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: MEALZ_2299
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: MEALZ_2303
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: MEALZ_2305
symbol: purH
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazolecarboxamide formyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2306
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family.


ensembl_gene_id: MEALZ_2307
symbol: CCE23988.1
gene_biotype: protein_coding
description:
  Conserved membrane protein of unknown function; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: MEALZ_2308
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: MEALZ_2309
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: MEALZ_2314
symbol: ctaD
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 1 (Cytochrome c oxidase polypeptide I) (Cytochrome aa3 subunit 1); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: MEALZ_2315
symbol: ctaC
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit II (Cytochrome aa3 subunit 2); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: MEALZ_2317
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: MEALZ_2318
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: MEALZ_2319
symbol: bioH
gene_biotype: protein_coding
description:
  Carboxylesterase BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: MEALZ_2320
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: MEALZ_2321
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: MEALZ_2325
symbol: CCE24006.1
gene_biotype: protein_coding
description:
  Putative Beta-lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2326
symbol: rfbB
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6 dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: MEALZ_2327
symbol: CCE24008.1
gene_biotype: protein_coding
description:
  Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_2337
symbol: glnS
gene_biotype: protein_coding
description:
  Glutamine tRNA synthetase (Glutamine--tRNA ligase) (GlnRS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2338
symbol: CCE24019.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase/phosphodiesterase with PAS/PAC and Chase sensor(S); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2341
symbol: CCE24022.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: MEALZ_2342
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: MEALZ_2345
symbol: CCE24026.1
gene_biotype: protein_coding
description:
  Multidrug resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MEALZ_2346
symbol: CCE24027.1
gene_biotype: protein_coding
description:
  Putative Efflux transporter, RND family, MFP subunit, AcrA/E family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MEALZ_2348
symbol: CCE24029.1
gene_biotype: protein_coding
description:
  Putative toxin of toxin-antitoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2371
symbol: iscS-2
gene_biotype: protein_coding
description:
  Fragment of Cysteine desulfurase (part 1); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2373
symbol: modE
gene_biotype: protein_coding
description:
  Molybdenum transport protein ModE; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_2376
symbol: modA
gene_biotype: protein_coding
description:
  Molybdate-binding periplasmic protein precursor; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_2378
symbol: modB
gene_biotype: protein_coding
description:
  ABC transporter, permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: MEALZ_2379
symbol: modC
gene_biotype: protein_coding
description:
  Molybdenum import ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: MEALZ_2383
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase (DAGK) (Diglyceride kinase) (DGK); Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: MEALZ_2385
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: MEALZ_2387
symbol: CCE24068.1
gene_biotype: protein_coding
description:
  RND efflux transporter, HME family, translocase subunit; Function of strongly homologous gene; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MEALZ_2401
symbol: CCE24082.1
gene_biotype: protein_coding
description:
  Putative TatD-related DNase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2402
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase (O-acetylserine sulfhydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: MEALZ_2404
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: MEALZ_2405
symbol: CCE24086.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: MEALZ_2406
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunit tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: MEALZ_2410
symbol: CCE24091.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulator, LuxR family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2414
symbol: CCE24095.1
gene_biotype: protein_coding
description:
  RND transporter, HAE1/HME family, permease protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MEALZ_2418
symbol: CCE24099.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulatory protein TctD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_2420
symbol: can
gene_biotype: protein_coding
description:
  Carbonic anhydrase 2 (Carbonate dehydratase 2); Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: MEALZ_2423
symbol: mptG
gene_biotype: protein_coding
description:
  Ribofuranosylaminobenzene 5'-phosphate (RFAP) synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2425
symbol: mch
gene_biotype: protein_coding
description:
  N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase (methenyl-H4MPT cyclohydrolase); Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.


ensembl_gene_id: MEALZ_2426
symbol: CCE24107.1
gene_biotype: protein_coding
description:
  Conserved protein (Orf5) involved in biosynthesis of tetrahydromethanopterin; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the RimK family.


ensembl_gene_id: MEALZ_2427
symbol: CCE24108.1
gene_biotype: protein_coding
description:
  Conserved protein (Orf7) involved in tetrahydromethanopterin-dependent formaldehyde oxidation; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2428
symbol: fae-2
gene_biotype: protein_coding
description:
  Formaldehyde-activating enzyme; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2434
symbol: CCE24114.1
gene_biotype: protein_coding
description:
  Conserved protein (Orf9) involved in biosynthesis of tetrahydromethanopterin; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2436
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: MEALZ_2437
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: MEALZ_2438
symbol: trpS
gene_biotype: protein_coding
description:
  Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: MEALZ_2443
symbol: CCE24123.1
gene_biotype: protein_coding
description:
  Putative outer membrane efflux protein (OprM-family protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2444
symbol: CCE24124.1
gene_biotype: protein_coding
description:
  Putative Efflux transporter, RND family, MFP subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MEALZ_2452
symbol: CCE24132.1
gene_biotype: protein_coding
description:
  Putative chemotaxis protein, methyltransferase domain CheR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2459
symbol: cobO
gene_biotype: protein_coding
description:
  Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: MEALZ_2471
symbol: mtnB
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: MEALZ_2472
symbol: mtnD
gene_biotype: protein_coding
description:
  Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: MEALZ_2473
symbol: mtnC
gene_biotype: protein_coding
description:
  Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: MEALZ_2479
symbol: ktrB
gene_biotype: protein_coding
description:
  Putative Ktr system potassium uptake protein B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_2480
symbol: CCE24160.1
gene_biotype: protein_coding
description:
  Putative Ktr system potassium uptake protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter.


ensembl_gene_id: MEALZ_2483
symbol: trkH
gene_biotype: protein_coding
description:
  Ktr system potassium uptake protein H; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: MEALZ_2484
symbol: trkA
gene_biotype: protein_coding
description:
  Trk system potassium uptake protein A; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_2485
symbol: CCE24163.1
gene_biotype: protein_coding
description:
  Putative two-component response regulator (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2492
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta (IHF-beta); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: MEALZ_2493
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: MEALZ_2494
symbol: cmk
gene_biotype: protein_coding
description:
  Cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2495
symbol: aroA
gene_biotype: protein_coding
description:
  3-enolpyruvylshikimate-5-phosphate synthetase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: MEALZ_2497
symbol: hisC-2
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: MEALZ_2498
symbol: pheA
gene_biotype: protein_coding
description:
  Bifunctional P-protein [Includes: Chorismate mutase (CM); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2499
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase (Phosphohydroxythreonine aminotransferase) (PSAT); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: MEALZ_2500
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: MEALZ_2502
symbol: hemN
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase (Coproporphyrinogenase) (Coprogen oxidase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: MEALZ_2507
symbol: cycK
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CycK; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2508
symbol: cycJ
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: MEALZ_2509
symbol: CCE24187.1
gene_biotype: protein_coding
description:
  Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: MEALZ_2510
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein, cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: MEALZ_2511
symbol: ccmB
gene_biotype: protein_coding
description:
  Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: MEALZ_2512
symbol: ccmA
gene_biotype: protein_coding
description:
  Heme export protein, cytochrome C-type biogenesis ccmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: MEALZ_2514
symbol: CCE24192.1
gene_biotype: protein_coding
description:
  Putative phosphorylase, carbohydrate binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2517
symbol: CCE24195.1
gene_biotype: protein_coding
description:
  Putative glycoside hydrolase/deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2523
symbol: shc
gene_biotype: protein_coding
description:
  Putative squalene--hopene cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2524
symbol: CCE24202.1
gene_biotype: protein_coding
description:
  Putative Bacterial regulatory protein, Crp; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_2527
symbol: cpo
gene_biotype: protein_coding
description:
  Putative non-heme haloperoxidase, alpha/beta hydrolase fold; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2528
symbol: sndH
gene_biotype: protein_coding
description:
  L-sorbosone dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2530
symbol: CCE24208.1
gene_biotype: protein_coding
description:
  Putative stress response protein CsbD-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: MEALZ_2533
symbol: CCE24211.1
gene_biotype: protein_coding
description:
  Putative OmpA/MotB domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2557
symbol: CCE24232.1
gene_biotype: protein_coding
description:
  Putative ribonuclease BN; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2572
symbol: xfp
gene_biotype: protein_coding
description:
  D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2580
symbol: CCE24255.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative stress response protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: MEALZ_2583
symbol: CCE24258.1
gene_biotype: protein_coding
description:
  Putative Transport-associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_2591
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: MEALZ_2592
symbol: clpA
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpA; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family.


ensembl_gene_id: MEALZ_2593
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: MEALZ_2594
symbol: nudJ
gene_biotype: protein_coding
description:
  Putative hydrolase (Nudix family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: MEALZ_2595
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: MEALZ_2596
symbol: purB
gene_biotype: protein_coding
description:
  Adenylosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: MEALZ_2598
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: MEALZ_2611
symbol: cusA
gene_biotype: protein_coding
description:
  Cation efflux system protein CusA; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MEALZ_2612
symbol: CCE24287.1
gene_biotype: protein_coding
description:
  Putative dihydrodipicolinate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DapA family.


ensembl_gene_id: MEALZ_2614
symbol: CCE24289.1
gene_biotype: protein_coding
description:
  Putative pyridoxamine 5'-phosphate oxidase, putative flavin-nucleotide-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2622
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: MEALZ_2623
symbol: fabB
gene_biotype: protein_coding
description:
  3-oxoacyl synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: MEALZ_2624
symbol: fabA
gene_biotype: protein_coding
description:
  Beta-hydroxydecanoyl thioester dehydrase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: MEALZ_2640
symbol: cysG-2
gene_biotype: protein_coding
description:
  Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: MEALZ_2641
symbol: CCE24316.1
gene_biotype: protein_coding
description:
  Putative WD40 domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2644
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase (citrulline-aspartate ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: MEALZ_2648
symbol: pntA
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: MEALZ_2649
symbol: pntB
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: MEALZ_2651
symbol: estB
gene_biotype: protein_coding
description:
  Putative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2652
symbol: CCE24327.1
gene_biotype: protein_coding
description:
  Putative extracellular solute-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: MEALZ_2660
symbol: apeB
gene_biotype: protein_coding
description:
  Putative M18 family aminopeptidase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2661
symbol: msrB
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrB (Peptide-methionine (R)-S-oxide reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: MEALZ_2663
symbol: oadG
gene_biotype: protein_coding
description:
  Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.


ensembl_gene_id: MEALZ_2665
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid aminotransferase (BCAT); Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: MEALZ_2666
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: MEALZ_2676
symbol: CCE24351.1
gene_biotype: protein_coding
description:
  Putative chaperone-modulator protein CbpM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_2679
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase (ubiquinone), Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: MEALZ_2680
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: MEALZ_2690
symbol: CCE24365.1
gene_biotype: protein_coding
description:
  Putative Glycosyl transferase family 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2697
symbol: CCE24372.1
gene_biotype: protein_coding
description:
  Putative nucleotidyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2703
symbol: CCE24378.1
gene_biotype: protein_coding
description:
  Putative formyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2705
symbol: CCE24380.1
gene_biotype: protein_coding
description:
  Putative phenylacetate--CoA ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2706
symbol: CCE24381.1
gene_biotype: protein_coding
description:
  Putative AMP-dependent synthetase and ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2707
symbol: CCE24382.1
gene_biotype: protein_coding
description:
  Putative ornithine/diaminopimelate PLP-dependent decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the Orn/Lys/Arg decarboxylase class-II family.


ensembl_gene_id: MEALZ_2723
symbol: CCE24397.1
gene_biotype: protein_coding
description:
  Putative aminoglycoside N(3')-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2732
symbol: CCE24404.1
gene_biotype: protein_coding
description:
  Putative CapK protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2734
symbol: CCE24406.1
gene_biotype: protein_coding
description:
  Putative Glycosyl transferase group 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2739
symbol: rffA
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein, putative TDP-4-oxo-6-deoxy-D-glucose transaminase; Function of strongly homologous gene; enzyme; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: MEALZ_2744
symbol: CCE24416.1
gene_biotype: protein_coding
description:
  Putative Uncharacterized glycosyltransferase ykcC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2745
symbol: rfbA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase (dTDP-glucose synthase) (dTDP-glucose pyrophosphorylase); Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: MEALZ_2748
symbol: CCE24420.1
gene_biotype: protein_coding
description:
  Putative membrane-associated enzyme (IPR017850); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.


ensembl_gene_id: MEALZ_2749
symbol: CCE24421.1
gene_biotype: protein_coding
description:
  Putative exonuclease SbcC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2750
symbol: sbcD
gene_biotype: protein_coding
description:
  Putative exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: MEALZ_2754
symbol: galU
gene_biotype: protein_coding
description:
  Glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2755
symbol: manC
gene_biotype: protein_coding
description:
  Mannose-1-phosphate guanylyltransferase [GDP] (GDP-mannose pyrophosphorylase) (GMP); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: MEALZ_2758
symbol: galE-2
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase (Galactowaldenase) (UDP-galactose 4-epimerase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: MEALZ_2767
symbol: CCE24439.1
gene_biotype: protein_coding
description:
  Putative flavoprotein oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2768
symbol: iscA
gene_biotype: protein_coding
description:
  Iron-binding protein iscA (Iron-sulfur cluster assembly protein); Function of homologous gene experimentally demonstrated in an other organism; cell process; Belongs to the HesB/IscA family.


ensembl_gene_id: MEALZ_2770
symbol: iscR
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly transcription factor IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: MEALZ_2772
symbol: trmJ
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: MEALZ_2773
symbol: suhB
gene_biotype: protein_coding
description:
  Inositol-1-monophosphatase (IMPase) (Inositol-1-phosphatase) (I-1-Pase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: MEALZ_2778
symbol: CCE24448.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative membrane protease; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_2780
symbol: CCE24450.1
gene_biotype: protein_coding
description:
  CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: MEALZ_2784
symbol: recQ
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecQ; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2785
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: MEALZ_2788
symbol: hslO
gene_biotype: protein_coding
description:
  33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: MEALZ_2789
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: MEALZ_2791
symbol: CCE24461.1
gene_biotype: protein_coding
description:
  Putative two-component response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_2813
symbol: CCE24479.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function, PilT protein-like protein; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_2822
symbol: CCE24488.1
gene_biotype: protein_coding
description:
  Putative PEP motif anchor-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2830
symbol: aas
gene_biotype: protein_coding
description:
  Bifunctional protein aas [Includes: 2-acylglycerophosphoethanolamine acyltransferase; Acyl-[acyl-carrier-protein] synthetase].


ensembl_gene_id: MEALZ_2833
symbol: ppk-2
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: MEALZ_2834
symbol: CCE24500.1
gene_biotype: protein_coding
description:
  Putative type I restriction-modification system, restriction subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2837
symbol: CCE24503.1
gene_biotype: protein_coding
description:
  Putative type I restriction-modification system, subunit S; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2838
symbol: CCE24504.1
gene_biotype: protein_coding
description:
  Putative type I restriction-modification system, methyltransferase subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2842
symbol: CCE24508.1
gene_biotype: protein_coding
description:
  Putative excisionase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2843
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator homolog; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: MEALZ_2844
symbol: ask
gene_biotype: protein_coding
description:
  Aspartokinase (Aspartate kinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.


ensembl_gene_id: MEALZ_2845
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: MEALZ_2847
symbol: recA
gene_biotype: protein_coding
description:
  Protein RecA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: MEALZ_2849
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: MEALZ_2853
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: MEALZ_2857
symbol: CCE24523.1
gene_biotype: protein_coding
description:
  Putative Hydroxyacylglutathione hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2858
symbol: CCE24524.1
gene_biotype: protein_coding
description:
  Putative sucrose phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2859
symbol: fbp
gene_biotype: protein_coding
description:
  Putative fructose-1,6-bisphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2860
symbol: bcp
gene_biotype: protein_coding
description:
  Putative peroxiredoxin bcp; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2862
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: MEALZ_2864
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: MEALZ_2865
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2866
symbol: cysNC
gene_biotype: protein_coding
description:
  Bifunctional enzyme CysN/CysC [Includes: Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: MEALZ_2869
symbol: CCE24535.1
gene_biotype: protein_coding
description:
  Putative chemotaxis protein CheY; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MEALZ_2870
symbol: cheA
gene_biotype: protein_coding
description:
  Chemotaxis protein CheA; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_2871
symbol: cheW
gene_biotype: protein_coding
description:
  Chemotaxis protein CheW; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_2876
symbol: cheD
gene_biotype: protein_coding
description:
  Chemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: MEALZ_2877
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: MEALZ_2879
symbol: CCE24545.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: MEALZ_2887
symbol: CCE24553.1
gene_biotype: protein_coding
description:
  Putative Two-component hybrid sensor and regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2913
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: MEALZ_2914
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamin-monophosphate kinase (Thiamine-phosphate kinase); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: MEALZ_2915
symbol: nusB
gene_biotype: protein_coding
description:
  N utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: MEALZ_2916
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase (Lumazine synthase)(riboflavin synthase beta chain); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: MEALZ_2917
symbol: ribAB
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein ribAB [Includes: GTP cyclohydrolase-2 (GTP cyclohydrolase II); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: MEALZ_2919
symbol: ribD
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: MEALZ_2920
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: MEALZ_2932
symbol: xpsE
gene_biotype: protein_coding
description:
  General secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: MEALZ_2951
symbol: CCE24617.1
gene_biotype: protein_coding
description:
  Putative Calcium/calmodulin-dependent protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2952
symbol: CCE24618.1
gene_biotype: protein_coding
description:
  Putative Phosphonate-transporting ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2954
symbol: CCE24620.1
gene_biotype: protein_coding
description:
  Disulfide bond isomerase, DsbC/G-like protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: MEALZ_2955
symbol: CCE24621.1
gene_biotype: protein_coding
description:
  Putative Peptidase M50; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_2956
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: MEALZ_2958
symbol: uppS
gene_biotype: protein_coding
description:
  Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: MEALZ_2959
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor (Ribosome-releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: MEALZ_2960
symbol: pyrH
gene_biotype: protein_coding
description:
  Uridylate kinase (UK) (Uridine monophosphate kinase) (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP.


ensembl_gene_id: MEALZ_2961
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: MEALZ_2962
symbol: rpsB
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S2; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: MEALZ_2963
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase (MAP) (Peptidase M); Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: MEALZ_2964
symbol: glnD
gene_biotype: protein_coding
description:
  [Protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: MEALZ_2968
symbol: glt
gene_biotype: protein_coding
description:
  Glutamate synthase (NADPH); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_2970
symbol: rapA
gene_biotype: protein_coding
description:
  RNA polymerase-associated protein rapA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: MEALZ_2973
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: MEALZ_2985
symbol: CCE24651.1
gene_biotype: protein_coding
description:
  Putative TonB-dependent receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2990
symbol: CCE24656.1
gene_biotype: protein_coding
description:
  Putative Hemagglutinin-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2995
symbol: phoB
gene_biotype: protein_coding
description:
  Phosphate regulon transcriptional regulatory protein PhoB; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_2997
symbol: CCE24663.1
gene_biotype: protein_coding
description:
  Putative exported hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_2998
symbol: clpB
gene_biotype: protein_coding
description:
  Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: MEALZ_3005
symbol: CCE24671.1
gene_biotype: protein_coding
description:
  Putative nitrogen regulatory protein P-II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3010
symbol: CCE24676.1
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine-dependent methyltransferase, spermidine synthase-related; Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_3012
symbol: csp
gene_biotype: protein_coding
description:
  Cold shock protein, RNA helicase co-factor, RNA co-chaperone; Function of strongly homologous gene; factor.


ensembl_gene_id: MEALZ_3018
symbol: CCE24684.1
gene_biotype: protein_coding
description:
  Putative TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: MEALZ_3024
symbol: gltA-2
gene_biotype: protein_coding
description:
  Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.


ensembl_gene_id: MEALZ_3026
symbol: icd
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase, NAD-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3028
symbol: gloB
gene_biotype: protein_coding
description:
  Putative hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) GloB-like; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: MEALZ_3029
symbol: yheT
gene_biotype: protein_coding
description:
  Putative esterase yheT; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3031
symbol: deaD
gene_biotype: protein_coding
description:
  Cold-shock DEAD box protein A homolog; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: MEALZ_3032
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: MEALZ_3035
symbol: CCE24701.1
gene_biotype: protein_coding
description:
  Putative GGDEF/EAL-domain containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3039
symbol: CCE24705.1
gene_biotype: protein_coding
description:
  ABC transporter, putative nickel-or polyamine-transporting ATPase; Function of strongly homologous gene; transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MEALZ_3043
symbol: fabI
gene_biotype: protein_coding
description:
  Enoyl-[acyl-carrier-protein] reductase [NADH] (NADH-dependent enoyl-ACP reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3046
symbol: hupB
gene_biotype: protein_coding
description:
  DNA-binding protein HU-beta (NS1) (HU-1); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: MEALZ_3047
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: MEALZ_3048
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: MEALZ_3049
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp); Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: MEALZ_3050
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: MEALZ_3057
symbol: emrA
gene_biotype: protein_coding
description:
  Multidrug resistance protein A; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_3058
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: MEALZ_3059
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: MEALZ_3062
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: MEALZ_3063
symbol: hfq
gene_biotype: protein_coding
description:
  Protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: MEALZ_3070
symbol: waaA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: MEALZ_3073
symbol: CCE24739.1
gene_biotype: protein_coding
description:
  Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: MEALZ_3074
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: MEALZ_3075
symbol: argH
gene_biotype: protein_coding
description:
  Argininosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3078
symbol: CCE24744.1
gene_biotype: protein_coding
description:
  Conserved exported protein of unknown function; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: MEALZ_3079
symbol: gap
gene_biotype: protein_coding
description:
  Glyceraldehyde 3-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: MEALZ_3080
symbol: pykA-2
gene_biotype: protein_coding
description:
  Pyruvate kinase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.


ensembl_gene_id: MEALZ_3088
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: MEALZ_3089
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: MEALZ_3090
symbol: ispA
gene_biotype: protein_coding
description:
  Geranyltranstransferase (Farnesyl-diphosphate synthase) (FPP synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: MEALZ_3092
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: MEALZ_3095
symbol: CCE24760.1
gene_biotype: protein_coding
description:
  Putative radical SAM protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3107
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase (PTH); The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: MEALZ_3110
symbol: CCE24775.1
gene_biotype: protein_coding
description:
  Type IV pilus assembly PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: MEALZ_3111
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA (DNA repair protein Sms); DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: MEALZ_3114
symbol: CCE24779.1
gene_biotype: protein_coding
description:
  Putative peptidase S49; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3115
symbol: CCE24780.1
gene_biotype: protein_coding
description:
  Putative phosphoglycolate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3117
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E (RNase E); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: MEALZ_3123
symbol: lpxA-2
gene_biotype: protein_coding
description:
  Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: MEALZ_3124
symbol: fabZ
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: MEALZ_3126
symbol: bamA
gene_biotype: protein_coding
description:
  Putative Bacterial surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: MEALZ_3130
symbol: CCE24795.1
gene_biotype: protein_coding
description:
  Putative thymidine phosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3133
symbol: CCE24798.1
gene_biotype: protein_coding
description:
  Putative methyl-accepting chemotaxis sensory transducer; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3136
symbol: cheD-2
gene_biotype: protein_coding
description:
  Putative chemoreceptor glutamine deamidase CheD 1; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: MEALZ_3139
symbol: rsmD
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: MEALZ_3140
symbol: CCE24805.1
gene_biotype: protein_coding
description:
  Putative peptidase M16; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3141
symbol: CCE24806.1
gene_biotype: protein_coding
description:
  Putative peptidase M16; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M16 family.


ensembl_gene_id: MEALZ_3142
symbol: cyoE
gene_biotype: protein_coding
description:
  Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: MEALZ_3151
symbol: CCE24816.1
gene_biotype: protein_coding
description:
  Putative CheW protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3153
symbol: CCE24818.1
gene_biotype: protein_coding
description:
  Putative flagellar motor protein MotD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: MEALZ_3154
symbol: motA
gene_biotype: protein_coding
description:
  Motility protein A; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MEALZ_3155
symbol: cheB-3
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase 2; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: MEALZ_3157
symbol: CCE24822.1
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: MEALZ_3158
symbol: cheY
gene_biotype: protein_coding
description:
  Chemotaxis protein CheY; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_3159
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor for flagellar operon (Sigma-F factor) (Sigma-27) (Sigma-28); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: MEALZ_3162
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: MEALZ_3163
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: MEALZ_3164
symbol: CCE24829.1
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: MEALZ_3165
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: MEALZ_3166
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP Precursor; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: MEALZ_3168
symbol: fliN
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: MEALZ_3169
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: MEALZ_3170
symbol: CCE24835.1
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: MEALZ_3172
symbol: CCE24837.1
gene_biotype: protein_coding
description:
  Putative Membrane protein-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3176
symbol: CCE24841.1
gene_biotype: protein_coding
description:
  Putative Type II secretion system protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3177
symbol: cpaF
gene_biotype: protein_coding
description:
  Putative type II secretion system protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3180
symbol: CCE24845.1
gene_biotype: protein_coding
description:
  Putative Flp pilus assembly CpaB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3182
symbol: CCE24847.1
gene_biotype: protein_coding
description:
  Putative exported protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3194
symbol: CCE24859.1
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: MEALZ_3195
symbol: CCE24860.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: MEALZ_3196
symbol: CCE24861.1
gene_biotype: protein_coding
description:
  Putative peptidase, M50 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3197
symbol: CCE24862.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative translation factor; Homologs of previously reported genes of unknown function; Belongs to the SUA5 family.


ensembl_gene_id: MEALZ_3199
symbol: CCE24864.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent helicase HI_0387; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3200
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: MEALZ_3201
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: MEALZ_3204
symbol: CCE24869.1
gene_biotype: protein_coding
description:
  Putative Glycine cleavage system transcriptional repressor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3205
symbol: CCE24870.1
gene_biotype: protein_coding
description:
  Putative peroxiredoxin Bcp (Thioredoxin reductase) (Bacterioferritin comigratory protein homolog); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3206
symbol: CCE24871.1
gene_biotype: protein_coding
description:
  Putative Phosphate starvation-inducible protein PhoH-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.


ensembl_gene_id: MEALZ_3208
symbol: perM
gene_biotype: protein_coding
description:
  Putative permease perM homolog; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3211
symbol: CCE24876.1
gene_biotype: protein_coding
description:
  Peptidase M48 Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: MEALZ_3215
symbol: mtkB
gene_biotype: protein_coding
description:
  Malate thiokinase, small subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: MEALZ_3216
symbol: mtkA
gene_biotype: protein_coding
description:
  Malate thiokinase, large subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: MEALZ_3217
symbol: mclA1
gene_biotype: protein_coding
description:
  malyl-CoA lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: MEALZ_3218
symbol: sgaA
gene_biotype: protein_coding
description:
  Serine-glyoxylate aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3219
symbol: hpr2
gene_biotype: protein_coding
description:
  2-hydroxyacid dehydrogenase NAD-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: MEALZ_3220
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: MEALZ_3221
symbol: mtdA
gene_biotype: protein_coding
description:
  Bifunctional protein mdtA [NADP-dependent methylenetetrahydromethanopterin dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3222
symbol: gck2
gene_biotype: protein_coding
description:
  Glycerate 2-kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3223
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: MEALZ_3224
symbol: ftfL
gene_biotype: protein_coding
description:
  Formate-tetrahydrofolate ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: MEALZ_3227
symbol: cpsG
gene_biotype: protein_coding
description:
  Phosphomannomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3231
symbol: tpx
gene_biotype: protein_coding
description:
  Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: MEALZ_3232
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: MEALZ_3236
symbol: aroBK
gene_biotype: protein_coding
description:
  Fragment of bifunctional protein [Includes: 3-dehydroquinate synthase; Function of strongly homologous gene; enzyme.


ensembl_gene_id: MEALZ_3240
symbol: CCE24905.1
gene_biotype: protein_coding
description:
  Putative Type IV pilus assembly protein PilM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: MEALZ_3241
symbol: mrcA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1A (PBP-1a) (PBP1a); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3244
symbol: CCE24909.1
gene_biotype: protein_coding
description:
  Putative transporter, SSS family; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: MEALZ_3246
symbol: ectD
gene_biotype: protein_coding
description:
  Putative ectoine hydroxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3247
symbol: ask-2
gene_biotype: protein_coding
description:
  Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3248
symbol: ectC
gene_biotype: protein_coding
description:
  L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.


ensembl_gene_id: MEALZ_3249
symbol: ectB
gene_biotype: protein_coding
description:
  Diaminobutyrate-2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: MEALZ_3250
symbol: ectA
gene_biotype: protein_coding
description:
  L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A; Belongs to the acetyltransferase family. EctA subfamily.


ensembl_gene_id: MEALZ_3251
symbol: ectR1
gene_biotype: protein_coding
description:
  Ectoine biosynthesis gene repressor; Function experimentally demonstrated in the studied strain; regulator.


ensembl_gene_id: MEALZ_3254
symbol: CCE24919.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: MEALZ_3255
symbol: CCE24920.1
gene_biotype: protein_coding
description:
  Putative S-adenosyl-L-methionine-dependent methyltransferase, UbiG-related; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3257
symbol: CCE24922.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MEALZ_3258
symbol: CCE24923.1
gene_biotype: protein_coding
description:
  Putative S-adenosyl-L-methionine-dependent methyltransferase, UbiE-related; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3266
symbol: CCE24931.1
gene_biotype: protein_coding
description:
  Putative ABC-2 type transporter superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3286
symbol: CCE24951.1
gene_biotype: protein_coding
description:
  Putative permease, major facilitator superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_3287
symbol: nhaD-2
gene_biotype: protein_coding
description:
  NhaD-type Na+(Li+)/H+ antiporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_3288
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite/nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3290
symbol: sucD
gene_biotype: protein_coding
description:
  Succinyl-CoA ligase [ADP-forming] subunit alpha (Succinyl-CoA synthetase subunit alpha) (SCS-alpha); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: MEALZ_3291
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: MEALZ_3293
symbol: pilR
gene_biotype: protein_coding
description:
  Type 4 fimbriae expression regulatory protein; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_3297
symbol: pepP
gene_biotype: protein_coding
description:
  Xaa-Pro aminopeptidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase M24B family.


ensembl_gene_id: MEALZ_3300
symbol: CCE24965.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: MEALZ_3302
symbol: pfp
gene_biotype: protein_coding
description:
  Pyrophosphate-fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK g [...]


ensembl_gene_id: MEALZ_3304
symbol: CCE24968.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function, nucleotide-binding motif; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_3305
symbol: CCE24969.1
gene_biotype: protein_coding
description:
  Putative SAM-binding Fe-S oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3311
symbol: CCE24975.1
gene_biotype: protein_coding
description:
  Putative phage SPO1 DNA polymerase-related protein, uracil-DNA glycosylase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3312
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: MEALZ_3313
symbol: CCE24977.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol/serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: MEALZ_3314
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: MEALZ_3315
symbol: ilvH
gene_biotype: protein_coding
description:
  Acetolactate synthase I/III small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3316
symbol: ilvI
gene_biotype: protein_coding
description:
  Acetolactate synthase large subunit (AHAS) (Acetohydroxy-acid synthase large subunit) (ALS); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3319
symbol: moaE
gene_biotype: protein_coding
description:
  Molybdopterin synthase catalytic subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3321
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: MEALZ_3322
symbol: CCE24986.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3323
symbol: sodB
gene_biotype: protein_coding
description:
  Superoxide dismutase [Fe]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: MEALZ_3327
symbol: rplQ
gene_biotype: protein_coding
description:
  50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MEALZ_3328
symbol: rpoA
gene_biotype: protein_coding
description:
  RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: MEALZ_3329
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: MEALZ_3330
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: MEALZ_3331
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: MEALZ_3332
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: MEALZ_3333
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: MEALZ_3335
symbol: rpmD
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MEALZ_3336
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: MEALZ_3337
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: MEALZ_3338
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: MEALZ_3339
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: MEALZ_3340
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: MEALZ_3341
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: MEALZ_3342
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: MEALZ_3343
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: MEALZ_3344
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: MEALZ_3346
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: MEALZ_3347
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: MEALZ_3348
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: MEALZ_3349
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: MEALZ_3350
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: MEALZ_3351
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: MEALZ_3353
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: MEALZ_3354
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: MEALZ_3355
symbol: tufB
gene_biotype: protein_coding
description:
  Elongation factor Tu-B (EF-Tu-B); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: MEALZ_3356
symbol: tufA
gene_biotype: protein_coding
description:
  Elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: MEALZ_3357
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: MEALZ_3358
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: MEALZ_3359
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: MEALZ_3361
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: MEALZ_3362
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: MEALZ_3363
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: MEALZ_3364
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: MEALZ_3365
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: MEALZ_3366
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: MEALZ_3367
symbol: tufB-2
gene_biotype: protein_coding
description:
  Elongation factor Tu-B (EF-Tu-B); Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MEALZ_3368
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: MEALZ_3369
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: MEALZ_3370
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: MEALZ_3371
symbol: CCE25034.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB (modular protein); Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: MEALZ_3373
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA reductase (GluTR); Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: MEALZ_3374
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: MEALZ_3375
symbol: prmC
gene_biotype: protein_coding
description:
  Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: MEALZ_3379
symbol: gatB
gene_biotype: protein_coding
description:
  Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: MEALZ_3381
symbol: gatA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: MEALZ_3382
symbol: gatC
gene_biotype: protein_coding
description:
  Putative Glutamyl-tRNA(Gln) amidotransferase subunit C (Glu-ADT subunit C); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: MEALZ_3383
symbol: mreB
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreB; Function of homologous gene experimentally demonstrated in an other organism; phenotype.


ensembl_gene_id: MEALZ_3385
symbol: CCE25048.1
gene_biotype: protein_coding
description:
  Putative rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: MEALZ_3386
symbol: mrdA
gene_biotype: protein_coding
description:
  Putative Penicillin-binding protein 2 (PBP-2) (MrdA); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: MEALZ_3387
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: MEALZ_3389
symbol: CCE25052.1
gene_biotype: protein_coding
description:
  Putative penicillin-binding (D-alanyl-d-alanine carboxypeptidase) transmembrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S11 family.


ensembl_gene_id: MEALZ_3392
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyl-[acyl-carrier-protein]-protein-N- lipoyltransferase (Lipoate-protein ligase B); Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: MEALZ_3393
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: MEALZ_3394
symbol: CCE25057.1
gene_biotype: protein_coding
description:
  Putative transcription accessory protein TEX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3396
symbol: CCE25059.1
gene_biotype: protein_coding
description:
  Putative sulfur oxidation protein SoxB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: MEALZ_3401
symbol: leuS
gene_biotype: protein_coding
description:
  leucyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: MEALZ_3402
symbol: lptE
gene_biotype: protein_coding
description:
  Putative LPS-assembly lipoprotein RlpB precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: MEALZ_3407
symbol: CCE25070.1
gene_biotype: protein_coding
description:
  Putative antitoxin of gyrase inhibiting toxin-antitoxin system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_3408
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.


ensembl_gene_id: MEALZ_3409
symbol: speA
gene_biotype: protein_coding
description:
  Arginine decarboxylase, PLP-binding, biosynthetic; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.


ensembl_gene_id: MEALZ_3413
symbol: metAS
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: MEALZ_3417
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3422
symbol: CCE25085.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative alkylphosphonate uptake protein PhnA; Homologs of previously reported genes of unknown function.


ensembl_gene_id: MEALZ_3423
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: MEALZ_3424
symbol: smg
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the Smg family.


ensembl_gene_id: MEALZ_3425
symbol: CCE25088.1
gene_biotype: protein_coding
description:
  Putative DNA protecting protein DprA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.


ensembl_gene_id: MEALZ_3427
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase (PDF); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: MEALZ_3428
symbol: fmt
gene_biotype: protein_coding
description:
  Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: MEALZ_3429
symbol: rsmB
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: MEALZ_3432
symbol: glnG-2
gene_biotype: protein_coding
description:
  Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator.


ensembl_gene_id: MEALZ_3433
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: MEALZ_3434
symbol: rpsI
gene_biotype: protein_coding
description:
  30S ribosomal protein S9; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: MEALZ_3435
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase biosynthetic (Threonine deaminase); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: MEALZ_3436
symbol: rpiA-2
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase A (Phosphoriboisomerase A) (PRI); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: MEALZ_3440
symbol: mxaC
gene_biotype: protein_coding
description:
  MxaC protein involved in methanol oxidation; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MEALZ_3441
symbol: CCE25104.1
gene_biotype: protein_coding
description:
  Putative MxaA protein involved in methanol oxidation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3442
symbol: CCE25105.1
gene_biotype: protein_coding
description:
  Putative MxaS protein involved in methanol oxidation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3445
symbol: mxaI
gene_biotype: protein_coding
description:
  Methanol dehydrogenase, small subunit; Catalyzes the oxidation of primary alcohols including methanol.


ensembl_gene_id: MEALZ_3446
symbol: mxaG
gene_biotype: protein_coding
description:
  Cytochrome c-L; Function of homologous gene experimentally demonstrated in an other organism; membrane component.


ensembl_gene_id: MEALZ_3447
symbol: mxaJ
gene_biotype: protein_coding
description:
  Protein MxaJ involved in regulation of methanol oxidation; Function of homologous gene experimentally demonstrated in an other organism; membrane component.


ensembl_gene_id: MEALZ_3448
symbol: mxaF
gene_biotype: protein_coding
description:
  Methanol dehydrogenase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3449
symbol: CCE25112.1
gene_biotype: protein_coding
description:
  DNA binding response regulator MxaB, LuxR family, involved in regulation of methanol oxidation; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MEALZ_3453
symbol: mxaD
gene_biotype: protein_coding
description:
  MxaD-like protein, involved in methanol oxidation; Homologs of previously reported genes of unknown function; factor.


ensembl_gene_id: MEALZ_3455
symbol: CCE25118.1
gene_biotype: protein_coding
description:
  Putative ribonuclease of the metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3456
symbol: corA-2
gene_biotype: protein_coding
description:
  Magnesium transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: MEALZ_3461
symbol: rimO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: MEALZ_3462
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: MEALZ_3463
symbol: CCE25126.1
gene_biotype: protein_coding
description:
  ATPase, AAA family protein; Function of homologous gene experimentally demonstrated in an other organism; cell process.


ensembl_gene_id: MEALZ_3464
symbol: lolA
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: MEALZ_3465
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: MEALZ_3467
symbol: hemB
gene_biotype: protein_coding
description:
  Delta-aminolevulinic acid dehydratase (Porphobilinogen synthase) (ALAD) (ALADH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family.


ensembl_gene_id: MEALZ_3469
symbol: cmoA
gene_biotype: protein_coding
description:
  tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: MEALZ_3470
symbol: cmoB
gene_biotype: protein_coding
description:
  tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: MEALZ_3472
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: MEALZ_3473
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: MEALZ_3476
symbol: pmbA
gene_biotype: protein_coding
description:
  Protein pmbA (Protein tldE); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3477
symbol: tldD
gene_biotype: protein_coding
description:
  Protein tldD homolog; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3479
symbol: CCE25142.1
gene_biotype: protein_coding
description:
  Putative nitrilase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3481
symbol: cafA
gene_biotype: protein_coding
description:
  RNase G (ribonuclease G); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3482
symbol: CCE25145.1
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: MEALZ_3483
symbol: rlmH
gene_biotype: protein_coding
description:
  Putative methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: MEALZ_3487
symbol: CCE25150.1
gene_biotype: protein_coding
description:
  Putative mxaA protein, involved in Ca2+ insertion in methanol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3491
symbol: fchA
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3492
symbol: cysS
gene_biotype: protein_coding
description:
  Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: MEALZ_3494
symbol: ppiA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase B (PPIase B) (rotamase B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: MEALZ_3495
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: MEALZ_3497
symbol: xoxF
gene_biotype: protein_coding
description:
  Putative dehydrogenase xoxF; Function of homologous gene experimentally demonstrated in an other organism.


ensembl_gene_id: MEALZ_3499
symbol: glgB2
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: MEALZ_3500
symbol: amyA
gene_biotype: protein_coding
description:
  Alpha amylase family protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3502
symbol: amyC
gene_biotype: protein_coding
description:
  Alpha-amylase/Glycoside hydrolase, family 57; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glycosyl hydrolase 57 family.


ensembl_gene_id: MEALZ_3504
symbol: malQ
gene_biotype: protein_coding
description:
  4-alpha-glucanotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3505
symbol: manB
gene_biotype: protein_coding
description:
  Alpha-mannosidosis/Glycoside hydrolase, family 57; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3506
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: MEALZ_3510
symbol: surA
gene_biotype: protein_coding
description:
  Putative chaperone surA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: MEALZ_3511
symbol: lptD
gene_biotype: protein_coding
description:
  Putative LPS-assembly protein lptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: MEALZ_3512
symbol: aphA1
gene_biotype: protein_coding
description:
  Putative aminoglycoside phosphotransferase involved in cell wall biosynthesis; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3513
symbol: RfbA
gene_biotype: protein_coding
description:
  Putative dTDP-glucose pyrophosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3518
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: MEALZ_3520
symbol: mtnP
gene_biotype: protein_coding
description:
  Putative S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.


ensembl_gene_id: MEALZ_3522
symbol: adh
gene_biotype: protein_coding
description:
  Membrane-associated quinoprotein formaldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3526
symbol: asdB
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: MEALZ_3528
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: MEALZ_3529
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: MEALZ_3530
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase (ATP-AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: MEALZ_3534
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase, aerobic (Coproporphyrinogenase) (Coprogen oxidase); Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: MEALZ_3537
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor greB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: MEALZ_3538
symbol: rffD
gene_biotype: protein_coding
description:
  UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: MEALZ_3543
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: MEALZ_3544
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent Hsl protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: MEALZ_3546
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: MEALZ_3548
symbol: ubiB
gene_biotype: protein_coding
description:
  2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.


ensembl_gene_id: MEALZ_3549
symbol: pgk
gene_biotype: protein_coding
description:
  Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: MEALZ_3550
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: MEALZ_3551
symbol: spoT
gene_biotype: protein_coding
description:
  GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: MEALZ_3553
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: MEALZ_3554
symbol: ubiC
gene_biotype: protein_coding
description:
  Putative chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: MEALZ_3556
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde 2,1-aminomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3558
symbol: CCE25216.1
gene_biotype: protein_coding
description:
  Putative phosphatidylethanolamine N-methyltransferase (pmtA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3559
symbol: hspQ
gene_biotype: protein_coding
description:
  Putative heat shock protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MEALZ_3560
symbol: ribA-2
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: MEALZ_3561
symbol: CCE25219.1
gene_biotype: protein_coding
description:
  Putative hippurate hydrolase protein HipO (Benzoylglycine amidohydrolase) (Hippuricase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3562
symbol: lexA-2
gene_biotype: protein_coding
description:
  Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: MEALZ_3566
symbol: CCE25224.1
gene_biotype: protein_coding
description:
  Putative BarA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3580
symbol: nadC
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide pyrophosphorylase (carboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.


ensembl_gene_id: MEALZ_3582
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: MEALZ_3583
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucine tRNA synthetase (Isoleucine--tRNA ligase) (IleRS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: MEALZ_3584
symbol: ribF
gene_biotype: protein_coding
description:
  Bifunctional riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase (Flavokinase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribF family.


ensembl_gene_id: MEALZ_3586
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase (Gamma-glutamyl kinase) (GK); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: MEALZ_3587
symbol: obg
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: MEALZ_3588
symbol: rpmA
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: MEALZ_3589
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: MEALZ_3590
symbol: ispB
gene_biotype: protein_coding
description:
  Octaprenyl-diphosphate synthase (Octaprenyl pyrophosphate synthetase) (OPP synthetase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: MEALZ_3594
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (UDP-3-O-acyl-GlcNAc deacetylase); Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: MEALZ_3595
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: MEALZ_3596
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: MEALZ_3597
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: MEALZ_3598
symbol: ddlB
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase B (D-alanylalanine synthetase B) (D-Ala-D-Ala ligase B); Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: MEALZ_3600
symbol: murC
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate--L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase); Cell wall formation; Belongs to the MurCDEF family.


ensembl_gene_id: MEALZ_3601
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: MEALZ_3602
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: MEALZ_3603
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: MEALZ_3604
symbol: mraY
gene_biotype: protein_coding
description:
  Phospho-N-acetylmuramoyl-pentapeptide- transferase (UDP-MurNAc-pentapeptide phosphotransferase); First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: MEALZ_3605
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: MEALZ_3606
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: MEALZ_3607
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.


ensembl_gene_id: MEALZ_3608
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: MEALZ_3609
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-dependent methyl transferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: MEALZ_3612
symbol: rsmI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein, putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: MEALZ_3614
symbol: CCE25272.1
gene_biotype: protein_coding
description:
  Putative endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF0102 family.


ensembl_gene_id: MEALZ_3615
symbol: diaA
gene_biotype: protein_coding
description:
  DnaA initiator-associating protein DiaA; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MEALZ_3618
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]


ensembl_gene_id: MEALZ_3620
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: MEALZ_3623
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: MEALZ_3633
symbol: acpP-2
gene_biotype: protein_coding
description:
  Acyl carrier protein 2; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: MEALZ_3638
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH (RNase PH) (tRNA nucleotidyltransferase); Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: MEALZ_3639
symbol: CCE25297.1
gene_biotype: protein_coding
description:
  HAM1 protein homolog; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: MEALZ_3642
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: MEALZ_3657
symbol: CCE25315.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0178 family.


ensembl_gene_id: MEALZ_3658
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: MEALZ_3664
symbol: CCE25322.1
gene_biotype: protein_coding
description:
  Putative Intracellular septation protein A; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3667
symbol: CCE25325.1
gene_biotype: protein_coding
description:
  Exported protein of unknown function; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: MEALZ_3668
symbol: CCE25326.1
gene_biotype: protein_coding
description:
  Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3671
symbol: CCE25329.1
gene_biotype: protein_coding
description:
  Putative type I site-specific restriction-modification system, S subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3681
symbol: CCE25337.1
gene_biotype: protein_coding
description:
  Putative halogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3685
symbol: CCE25341.1
gene_biotype: protein_coding
description:
  Putative Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3706
symbol: cas1-3
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: MEALZ_3729
symbol: tesA
gene_biotype: protein_coding
description:
  Acyl-CoA thioesterase I precursor (Protease I) (Lysophospholipase L1) (Lecithinase B); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3730
symbol: CCE25386.1
gene_biotype: protein_coding
description:
  Putative ATP-binding ABC transporter protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_3734
symbol: CCE25390.1
gene_biotype: protein_coding
description:
  Putative methyl-accepting chemotaxis protein IV; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3735
symbol: atpD-2
gene_biotype: protein_coding
description:
  ATP synthase subunit beta 2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: MEALZ_3736
symbol: atpC-2
gene_biotype: protein_coding
description:
  H+-transporting two-sector ATPase, delta/epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: MEALZ_3739
symbol: atpB-3
gene_biotype: protein_coding
description:
  ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: MEALZ_3740
symbol: atpE-2
gene_biotype: protein_coding
description:
  ATP synthase subunit c 2; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: MEALZ_3741
symbol: atpF-2
gene_biotype: protein_coding
description:
  ATP synthase subunit b 2 (fragment); Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: MEALZ_3742
symbol: atpA-3
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha 2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: MEALZ_3749
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (Murein peptide ligase); Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: MEALZ_3750
symbol: nemA
gene_biotype: protein_coding
description:
  N-ethylmaleimide reductase, FMN-linked; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MEALZ_3755
symbol: CCE25411.1
gene_biotype: protein_coding
description:
  Putative Transcriptional Regulator, Fis family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3761
symbol: mrp
gene_biotype: protein_coding
description:
  Protein Mrp homolog; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: MEALZ_3764
symbol: hmuV
gene_biotype: protein_coding
description:
  ABC-type hemin transport system, ATPase component; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: MEALZ_3765
symbol: hmuU
gene_biotype: protein_coding
description:
  ABC-type hemin transport system, permease component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: MEALZ_3766
symbol: hmuT
gene_biotype: protein_coding
description:
  ABC-type hemin transport system, periplasmic component; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MEALZ_3767
symbol: hugZ
gene_biotype: protein_coding
description:
  Putative heme iron utilization protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MEALZ_3769
symbol: CCE25425.1
gene_biotype: protein_coding
description:
  Putative hemin transport protein hmuS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MEALZ_3773
symbol: CCE25429.1
gene_biotype: protein_coding
description:
  Putative Outer membrane hemin receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3790
symbol: CCE25446.1
gene_biotype: protein_coding
description:
  Putative hydroxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MEALZ_3793
symbol: cbbA
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: MEALZ_3794
symbol: yoeB-2
gene_biotype: protein_coding
description:
  Toxin, YoeB-YefM toxin-antitoxin system; Function of homologous gene experimentally demonstrated in an other organism; factor.


