# pathwayInfo

id: PF16078
description: 2-oxoglutarate dehydrogenase N-terminus
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16078
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16078_2-oxoglutarate_dehydrogenase_N-terminus


id: PF16123
description: Hydroxyacylglutathione hydrolase C-terminus
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16123
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16123_Hydroxyacylglutathione_hydrolase_C-terminus


id: PF16177
description: Acetyl-coenzyme A synthetase N-terminus
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16177
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16177_Acetyl-coenzyme_A_synthetase_N-terminus


id: PF16198
description: tRNA pseudouridylate synthase B C-terminal domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16198
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16198_tRNA_pseudouridylate_synthase_B_C-terminal_domain


id: PF16320
description: Ribosomal protein L7/L12 dimerisation domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16320
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16320_Ribosomal_protein_L7/L12_dimerisation_domain


id: PF16321
description: Sigma 54 modulation/S30EA ribosomal protein C terminus
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16321
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16321_Sigma_54_modulation/S30EA_ribosomal_protein_C_terminus


id: PF16327
description: Cytochrome c-type biogenesis protein CcmF C-terminal
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16327
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16327_Cytochrome_c-type_biogenesis_protein_CcmF_C-terminal


id: PF16491
description: CAAX prenyl protease N-terminal, five membrane helices
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16491
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16491_CAAX_prenyl_protease_N-terminal,_five_membrane_helices


id: PF16576
description: Barrel-sandwich domain of CusB or HlyD membrane-fusion
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16576
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16576_Barrel-sandwich_domain_of_CusB_or_HlyD_membrane-fusion


id: PF16655
description: PhoD-like phosphatase, N-terminal domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16655
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16655_PhoD-like_phosphatase,_N-terminal_domain


id: PF16658
description: Class II release factor RF3, C-terminal domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16658
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16658_Class_II_release_factor_RF3,_C-terminal_domain


id: PF16870
description: 2-oxoglutarate dehydrogenase C-terminal
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16870
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16870_2-oxoglutarate_dehydrogenase_C-terminal


id: PF16881
description: N-terminal domain of lipoyl synthase of Radical_SAM family
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16881
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16881_N-terminal_domain_of_lipoyl_synthase_of_Radical_SAM_family


id: PF16916
description: Dimerisation domain of Zinc Transporter
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16916
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16916_Dimerisation_domain_of_Zinc_Transporter


id: PF16917
description: Biotin/lipoate A/B protein ligase family
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16917
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16917_Biotin/lipoate_A/B_protein_ligase_family


id: PF16925
description: Tetracyclin repressor-like, C-terminal domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF16925
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF16925_Tetracyclin_repressor-like,_C-terminal_domain


id: PF17092
description: Penicillin-binding protein OB-like domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17092
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF17092_Penicillin-binding_protein_OB-like_domain


id: PF17136
description: Ribosomal proteins 50S L24/mitochondrial 39S L24
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17136
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF17136_Ribosomal_proteins_50S_L24/mitochondrial_39S_L24


id: PF17297
description: Phosphoenolpyruvate carboxykinase N-terminal domain
memo: https://www.ebi.ac.uk/interpro/entry/pfam/PF17297
name:
  Protein Domains (Pfam).STRING_v12.0_1121123_STRINGid_PF17297_Phosphoenolpyruvate_carboxykinase_N-terminal_domain


id: SM00044
description: Adenylyl- / guanylyl cyclase, catalytic domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00044
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00044_Adenylyl-_/_guanylyl_cyclase,_catalytic_domain


id: SM00052
description: Putative diguanylate phosphodiesterase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00052
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00052_Putative_diguanylate_phosphodiesterase


id: SM00062
description: Bacterial periplasmic substrate-binding proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00062
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00062_Bacterial_periplasmic_substrate-binding_proteins


id: SM00065
description: Domain present in phytochromes and cGMP-specific phosphodiesterases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00065
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00065_Domain_present_in_phytochromes_and_cGMP-specific_phosphodiesterases.


id: SM00086
description: Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00086
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00086_Motif_C-terminal_to_PAS_motifs_(likely_to_contribute_to_PAS_structural_domain)


id: SM00100
description: Cyclic nucleotide-monophosphate binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00100
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00100_Cyclic_nucleotide-monophosphate_binding_domain


id: SM00116
description: Domain in cystathionine beta-synthase and other proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00116
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00116_Domain_in_cystathionine_beta-synthase_and_other_proteins.


id: SM00138
description: Methyltransferase, chemotaxis proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00138
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00138_Methyltransferase,_chemotaxis_proteins


id: SM00156
description: Protein phosphatase 2A homologues, catalytic domain.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00156
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00156_Protein_phosphatase_2A_homologues,_catalytic_domain.


id: SM00226
description: Low molecular weight phosphatase family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00226
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00226_Low_molecular_weight_phosphatase_family


id: SM00228
description: Domain present in PSD-95, Dlg, and ZO-1/2.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00228
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00228_Domain_present_in_PSD-95,_Dlg,_and_ZO-1/2.


id: SM00271
description: DnaJ molecular chaperone homology domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00271
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00271_DnaJ_molecular_chaperone_homology_domain


id: SM00278
description: Helix-hairpin-helix DNA-binding motif class 1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00278
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00278_Helix-hairpin-helix_DNA-binding_motif_class_1


id: SM00279
description: Helix-hairpin-helix class 2 (Pol1 family) motifs
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00279
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00279_Helix-hairpin-helix_class_2_(Pol1_family)_motifs


id: SM00304
description: HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00304
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00304_HAMP_(Histidine_kinases,_Adenylyl_cyclases,_Methyl_binding_proteins,_Phosphatases)_domain


id: SM00316
description: Ribosomal protein S1-like RNA-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00316
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00316_Ribosomal_protein_S1-like_RNA-binding_domain


id: SM00327
description: Von Willebrand factor (vWF) type A domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00327
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00327_Von_Willebrand_factor_(vWF)_type_A_domain


id: SM00342
description: Helix_turn_helix, arabinose operon control protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00342
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00342_Helix_turn_helix,_arabinose_operon_control_protein


id: SM00345
description: Helix_turn_helix gluconate operon transcriptional repressor
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00345
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00345_Helix_turn_helix_gluconate_operon_transcriptional_repressor


id: SM00347
description: Helix_turn_helix multiple antibiotic resistance protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00347
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00347_Helix_turn_helix_multiple_antibiotic_resistance_protein


id: SM00354
description: Helix_turn _helix lactose operon repressor
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00354
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00354_Helix_turn__helix_lactose_operon_repressor


id: SM00382
description: ATPases associated with a variety of cellular activities
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00382
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00382_ATPases_associated_with_a_variety_of_cellular_activities


id: SM00411
description: Bacterial (prokaryotic) histone like domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00411
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00411_Bacterial_(prokaryotic)_histone_like_domain


id: SM00418
description: Helix_turn_helix, Arsenical Resistance Operon Repressor
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00418
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00418_Helix_turn_helix,_Arsenical_Resistance_Operon_Repressor


id: SM00436
description: Bacterial DNA topoisomeraes I ATP-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00436
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00436_Bacterial_DNA_topoisomeraes_I_ATP-binding_domain


id: SM00437
description: Bacterial DNA topoisomerase I DNA-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00437
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00437_Bacterial_DNA_topoisomerase_I_DNA-binding_domain


id: SM00464
description: Found in ATP-dependent protease La (LON)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00464
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00464_Found_in_ATP-dependent_protease_La_(LON)


id: SM00471
description: Metal dependent phosphohydrolases with conserved HD motif.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00471
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00471_Metal_dependent_phosphohydrolases_with_conserved_HD_motif.


id: SM00479
description: Exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other exonucleases
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00479
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00479_Exonuclease_domain_in_DNA-polymerase_alpha_and_epsilon_chain,_ribonuclease_T_and_other_exonucleases


id: SM00481
description: DNA polymerase alpha chain like domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00481
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00481_DNA_polymerase_alpha_chain_like_domain


id: SM00490
description: Helicase superfamily c-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00490
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00490_Helicase_superfamily_c-terminal_domain


id: SM00493
description: Topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00493
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00493_Topoisomerases,_DnaG-type_primases,_OLD_family_nucleases_and_RecR_proteins


id: SM00525
description: Iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00525
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00525_Iron-sulpphur_binding_domain_in_DNA-(apurinic_or_apyrimidinic_site)_lyase_(subfamily_of_ENDO3)


id: SM00530
description: Helix-turn-helix XRE-family like proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00530
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00530_Helix-turn-helix_XRE-family_like_proteins


id: SM00533
description: DNA-binding domain of DNA mismatch repair MUTS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00533
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00533_DNA-binding_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00534
description: ATPase domain of DNA mismatch repair MUTS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00534
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00534_ATPase_domain_of_DNA_mismatch_repair_MUTS_family


id: SM00558
description: A domain family that is part of the cupin metalloenzyme superfamily.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00558
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00558_A_domain_family_that_is_part_of_the_cupin_metalloenzyme_superfamily.


id: SM00562
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00562
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00562_These_are_enzymes_that_catalyze_nonsubstrate_specific_conversions_of_nucleoside_diphosphates_to_nucleoside_triphosphates._These_enzymes_play_important_roles_in_bacterial_growth,_signal_transduction_and_pathogenicity.

description:
  These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.


id: SM00702
description: Prolyl 4-hydroxylase alpha subunit homologues.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00702
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00702_Prolyl_4-hydroxylase_alpha_subunit_homologues.


id: SM00704
description: CDGSH-type zinc finger. Function unknown.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00704
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00704_CDGSH-type_zinc_finger._Function_unknown.


id: SM00729
description: Elongator protein 3, MiaB family, Radical SAM
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00729
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00729_Elongator_protein_3,_MiaB_family,_Radical_SAM


id: SM00732
description: Likely ribonuclease with RNase H fold.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00732
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00732_Likely_ribonuclease_with_RNase_H_fold.


id: SM00738
description: In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00738
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00738_In_Spt5p,_this_domain_may_confer_affinity_for_Spt4p._It_possesses_a_RNP-like_fold.


id: SM00739
description: KOW (Kyprides, Ouzounis, Woese) motif.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00739
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00739_KOW_(Kyprides,_Ouzounis,_Woese)_motif.


id: SM00760
description: Bacterial dnaA protein helix-turn-helix domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00760
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00760_Bacterial_dnaA_protein_helix-turn-helix_domain


id: SM00833
description: Cobalamin synthesis protein cobW C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00833
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00833_Cobalamin_synthesis_protein_cobW_C-terminal_domain


id: SM00839
description: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00839
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00839_Glutamate/Leucine/Phenylalanine/Valine_dehydrogenase


id: SM00840
description: This DALR domain is found in cysteinyl-tRNA-synthetases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00840
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00840_This_DALR_domain_is_found_in_cysteinyl-tRNA-synthetases.


id: SM00843
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00843
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00843_This_domain_directs_oriented_DNA_translocation_and_forms_a_winged_helix_structure._Mutated_proteins_with_substitutions_in_the_FtsK_gamma_DNA-recognition_helix_are_impaired_in_DNA_binding.

description:
  This domain directs oriented DNA translocation and forms a winged helix structure. Mutated proteins with substitutions in the FtsK gamma DNA-recognition helix are impaired in DNA binding.


id: SM00846
description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00846
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00846_Glyceraldehyde_3-phosphate_dehydrogenase,_NAD_binding_domain


id: SM00847
description: Helicase associated domain (HA2) Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00847
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00847_Helicase_associated_domain_(HA2)__Add_an_annotation


id: SM00858
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00858
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00858_This_domain_family_includes_a_range_of_different_proteins._Such_as_antifreeze_proteins_and_flagellar_FlgA_proteins,_and_CpaB_pilus_proteins.

description:
  This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins.


id: SM00859
description: Semialdehyde dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00859
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00859_Semialdehyde_dehydrogenase,_NAD_binding_domain


id: SM00861
description: Transketolase, pyrimidine binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00861
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00861_Transketolase,_pyrimidine_binding_domain


id: SM00862
description: Transcriptional regulatory protein, C terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00862
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00862_Transcriptional_regulatory_protein,_C_terminal


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00865
description: Tubulin/FtsZ family, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00865
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00865_Tubulin/FtsZ_family,_C-terminal_domain


id: SM00866
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00866
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00866_The_UbiC_transcription_regulator-associated_(UTRA)_domain_is_a_conserved_ligand-binding_domain_that_has_a_similar_fold_to_PUBMED:12757941._It_is_believed_to_modulate_activity_of_bacterial_transcription_factors_in_response_to_binding_small_molecules.

description:
  The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to PUBMED:12757941. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.


id: SM00876
description: Biotin and Thiamin Synthesis associated domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00876
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00876_Biotin_and_Thiamin_Synthesis_associated_domain


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00898
description: Formamidopyrimidine-DNA glycosylase N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00898
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00898_Formamidopyrimidine-DNA_glycosylase_N-terminal_domain


id: SM00926
description: Molybdopterin oxidoreductase Fe4S4 domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00926
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00926_Molybdopterin_oxidoreductase_Fe4S4_domain


id: SM00928
description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00928
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00928_NADH-ubiquinone_oxidoreductase-F_iron-sulfur_binding_region


id: SM00929
description: NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00929
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00929_NADH-ubiquinone_oxidoreductase-G_iron-sulfur_binding_region


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00953
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00953
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00953_This_presumed_protein_contains_3_highly_conserved_polar_groups_that_could_form_an_active_site._These_are_an_arginine,_glutamate_and_serine,_hence_the_RES_domain._RES_is_found_widely_distributed_in_bacteria,_it_has_about_150_residues_in_length.

description:
  This presumed protein contains 3 highly conserved polar groups that could form an active site. These are an arginine, glutamate and serine, hence the RES domain. RES is found widely distributed in bacteria, it has about 150 residues in length.


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00956
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00956
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00956_This_DNA-binding_domain_is_found_in_the_RecQ_helicase_among_others_and_has_a_helix-turn-helix_structure._The_RQC_domain,_found_only_in_RecQ_family_enzymes,_is_a_high_affinity_G4_DNA_binding_domain_PUBMED:16530788.

description:
  This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain PUBMED:16530788.


id: SM00959
description: Rho termination factor, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00959
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00959_Rho_termination_factor,_N-terminal_domain


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00974
description: This entry represents the putative helicase A859L PUBMED:11897024.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00974
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00974_This_entry_represents_the_putative_helicase_A859L_PUBMED:11897024.


id: SM00978
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00978
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00978_Tim44_is_an_essential_component_of_the_machinery_that_mediates_the_translocation_of_nuclear-encoded_proteins_across_the_mitochondrial_inner_membrane_PUBMED:10430866._Tim44_is_thought_to_bind_phospholipids_of_the_mitochondrial_inner_membrane_both_by_...

description:
  Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane PUBMED:10430866. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by ...


id: SM00982
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00982
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00982_This_domain_is_found_in_proteins_necessary_for_strand-specific_repair_in_DNA_such_as_TRCF_in_Escherichia_coli._A_lesion_in_the_template_strand_blocks_the_RNA_polymerase_complex_(RNAP)._The_RNAP-DNA-RNA_complex_is_specifically_recognised_by_the_...

description:
  This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli. A lesion in the template strand blocks the RNA polymerase complex (RNAP). The RNAP-DNA-RNA complex is specifically recognised by the ...


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00992
description: Hemimethylated DNA-binding protein YccV like
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00992
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00992_Hemimethylated_DNA-binding_protein_YccV_like


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01016
description: Arginyl tRNA synthetase N terminal dom
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01016
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01016_Arginyl_tRNA_synthetase_N_terminal_dom


id: SM01080
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01080
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01080_CHASE2_is_an_extracellular_sensory_domain,_which_is_present_in_various_classes_of_transmembrane_receptors_that_are_parts_of_signal_transduction_pathways_in_bacteria._Specifically,_CHASE2_domains_are_found_in_histidine_kinases,_adenylate_cyclases,_...

description:
  CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, ...


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01230
description: Glutamine synthetase, catalytic domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01230
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01230_Glutamine_synthetase,_catalytic_domain


id: SM01232
description: Formamidopyrimidine-DNA glycosylase H2TH domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01232
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01232_Formamidopyrimidine-DNA_glycosylase_H2TH_domain


id: SM01234
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01234
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01234_This_domain_has_haemolytic_activity_(PMID:19306042)._It_is_found_in_short_(73-103_amino_acid)_proteins_and_contains_three_conserved_cysteine_residues.

description:
  This domain has haemolytic activity (PMID:19306042). It is found in short (73-103 amino acid) proteins and contains three conserved cysteine residues.


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01477
description: DDE transposase retroviral integrase sub-family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01477
name:
  Protein Domains (SMART).STRING_v12.0_1121123_STRINGid_SM01477_DDE_transposase_retroviral_integrase_sub-family


