# geneInfo

ensembl_gene_id: KS2013_1
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: KS2013_1005
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: KS2013_1007
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: KS2013_1008
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: KS2013_1012
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: KS2013_1017
symbol: gltX
gene_biotype: protein_coding
description:
  Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: KS2013_1024
symbol: AOE49744.1
gene_biotype: protein_coding
description:
  Putative phosphohistidine phosphatase, SixA; Pfam:pfam00300 Histidine phosphatase superfamily (branch 1).


ensembl_gene_id: KS2013_1026
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: KS2013_1027
symbol: AOE49747.1
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit clpA; Pfam:pfam07724 AAA domain (Cdc48 subfamily); Belongs to the ClpA/ClpB family.


ensembl_gene_id: KS2013_1028
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: KS2013_1029
symbol: bpt
gene_biotype: protein_coding
description:
  Putative arginyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: KS2013_103
symbol: AOE48833.1
gene_biotype: protein_coding
description:
  Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: KS2013_1030
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: KS2013_1039
symbol: AOE49759.1
gene_biotype: protein_coding
description:
  Agmatine deiminase; Pfam:pfam04371 Porphyromonas-type peptidyl-arginine deiminase; Belongs to the agmatine deiminase family.


ensembl_gene_id: KS2013_104
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: KS2013_1041
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: KS2013_1042
symbol: speH
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: KS2013_1045
symbol: AOE49765.1
gene_biotype: protein_coding
description:
  Pfam:pfam00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: KS2013_105
symbol: AOE48835.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LytTR family; Pfam:pfam00072 Response regulator receiver domain.


ensembl_gene_id: KS2013_1050
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: KS2013_1065
symbol: cysZ
gene_biotype: protein_coding
description:
  Sulfate transporter; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: KS2013_1066
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: KS2013_1067
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: KS2013_1068
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: KS2013_1072
symbol: rne
gene_biotype: protein_coding
description:
  Rne/Rng family ribonuclease; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: KS2013_1073
symbol: AOE49793.1
gene_biotype: protein_coding
description:
  23S rRNA pseudouridylate synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: KS2013_1074
symbol: AOE49794.1
gene_biotype: protein_coding
description:
  HAD-superfamily hydrolase, subfamily IA, variant 3; Pfam:pfam13419 Haloacid dehalogenase-like hydrolase.


ensembl_gene_id: KS2013_1075
symbol: AOE49795.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Pfam:pfam00578 AhpC/TSA family.


ensembl_gene_id: KS2013_1080
symbol: AOE49800.1
gene_biotype: protein_coding
description:
  Cation transporter, cation diffusion facilitator (CDF) family protein; Pfam:pfam01545 Cation efflux family; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: KS2013_1081
symbol: AOE49801.1
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: KS2013_1083
symbol: rpmF
gene_biotype: protein_coding
description:
  Pfam:pfam01783 Ribosomal L32p protein family; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: KS2013_1084
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: KS2013_1085
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: KS2013_1087
symbol: AOE49807.1
gene_biotype: protein_coding
description:
  3-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: KS2013_1089
symbol: AOE49809.1
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: KS2013_109
symbol: cyaY
gene_biotype: protein_coding
description:
  Protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: KS2013_1091
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: KS2013_1094
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: KS2013_1098
symbol: AOE49818.1
gene_biotype: protein_coding
description:
  Peptidase S8 and S53 subtilisin kexin sedolisin; Pfam:pfam00082 Subtilase family; Belongs to the peptidase S8 family.


ensembl_gene_id: KS2013_110
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: KS2013_1107
symbol: AOE49827.1
gene_biotype: protein_coding
description:
  Carboxyl-terminal protease; Pfam:pfam03572 Peptidase family S41; Belongs to the peptidase S41A family.


ensembl_gene_id: KS2013_1111
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: KS2013_1117
symbol: AOE49837.1
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Pfam:pfam04055 Radical SAM superfamily.


ensembl_gene_id: KS2013_112
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: KS2013_113
symbol: AOE48843.1
gene_biotype: protein_coding
description:
  HAD-superfamily hydrolase, subfamily IA, variant 1; Pfam:pfam00702 haloacid dehalogenase-like hydrolase.


ensembl_gene_id: KS2013_1130
symbol: AOE49850.1
gene_biotype: protein_coding
description:
  Pfam:pfam12700 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: KS2013_1131
symbol: AOE49851.1
gene_biotype: protein_coding
description:
  Putative silver efflux pump; Pfam:pfam00873 AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: KS2013_1137
symbol: AOE49857.1
gene_biotype: protein_coding
description:
  Heat shock protein Hsp20; Pfam:pfam00011 Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: KS2013_1140
symbol: AOE49860.1
gene_biotype: protein_coding
description:
  Putative thymidine phosphorylase; Pfam:pfam07831 Pyrimidine nucleoside phosphorylase C-terminal domain.


ensembl_gene_id: KS2013_1141
symbol: AOE49861.1
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Pfam:pfam13793 N-terminal domain of ribose phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.


ensembl_gene_id: KS2013_1151
symbol: AOE49871.1
gene_biotype: protein_coding
description:
  Protein tyrosine phosphatase; Pfam:pfam01451 Low molecular weight phosphotyrosine protein phosphatase.


ensembl_gene_id: KS2013_1152
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: KS2013_1154
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: KS2013_1155
symbol: msbA
gene_biotype: protein_coding
description:
  ATP-binding protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: KS2013_1160
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: KS2013_1161
symbol: AOE49881.1
gene_biotype: protein_coding
description:
  Lipoprotein releasing system, transmembrane protein, LolC/E family; Pfam:pfam12704 MacB-like periplasmic core domain.


ensembl_gene_id: KS2013_1164
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: KS2013_1170
symbol: AOE49890.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam03692 Putative zinc- or iron-chelating domain; Belongs to the UPF0260 family.


ensembl_gene_id: KS2013_1172
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: KS2013_1183
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: KS2013_1192
symbol: AOE49912.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: KS2013_1193
symbol: AOE49913.1
gene_biotype: protein_coding
description:
  PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: KS2013_1194
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: KS2013_12
symbol: KS2013_12
gene_biotype: protein_coding
description:
  Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: KS2013_1205
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator-like protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: KS2013_1207
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: KS2013_1209
symbol: recA
gene_biotype: protein_coding
description:
  Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: KS2013_1217
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: KS2013_1218
symbol: AOE49937.1
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin iron-sulfur binding domain protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: KS2013_1220
symbol: AOE49939.1
gene_biotype: protein_coding
description:
  Pfam:pfam02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: KS2013_1230
symbol: AOE49948.1
gene_biotype: protein_coding
description:
  Peptidase S9 prolyl oligopeptidase active site domain protein; Pfam:pfam00326 Prolyl oligopeptidase family.


ensembl_gene_id: KS2013_1232
symbol: cmoA
gene_biotype: protein_coding
description:
  tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: KS2013_1233
symbol: cmoB
gene_biotype: protein_coding
description:
  tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: KS2013_1236
symbol: AOE49954.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam13437 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: KS2013_1237
symbol: AOE49955.1
gene_biotype: protein_coding
description:
  Multidrug resistance protein; Pfam:pfam00873 AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: KS2013_124
symbol: AOE48854.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate ABC transporter; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: KS2013_1241
symbol: serS
gene_biotype: protein_coding
description:
  Serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: KS2013_1242
symbol: crcB
gene_biotype: protein_coding
description:
  Putative fluoride ion transporter CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: KS2013_1244
symbol: lolA
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: KS2013_1258
symbol: mnmA
gene_biotype: protein_coding
description:
  Thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: KS2013_1259
symbol: hflD
gene_biotype: protein_coding
description:
  High frequency lysogenization protein HflD-like protein; Pfam:pfam04356 Protein of unknown function (DUF489).


ensembl_gene_id: KS2013_1262
symbol: AOE49979.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam04542 Sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: KS2013_1266
symbol: AOE49981.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase; Pfam:pfam01066 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: KS2013_1270
symbol: clpB
gene_biotype: protein_coding
description:
  Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: KS2013_1272
symbol: AOE49987.1
gene_biotype: protein_coding
description:
  Polyphenol oxidase; Pfam:pfam02578 Multi-copper polyphenol oxidoreductase laccase; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: KS2013_1273
symbol: AOE49988.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: KS2013_1274
symbol: bamD
gene_biotype: protein_coding
description:
  Membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: KS2013_1276
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: KS2013_1278
symbol: AOE49993.1
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; Pfam:pfam00158 Sigma-54 interaction domain.


ensembl_gene_id: KS2013_1283
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: KS2013_1284
symbol: secD
gene_biotype: protein_coding
description:
  Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: KS2013_1285
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: KS2013_1286
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: KS2013_1287
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine tRNA ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: KS2013_1289
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: KS2013_129
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: KS2013_1292
symbol: AOE50006.1
gene_biotype: protein_coding
description:
  Acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: KS2013_1296
symbol: AOE50010.1
gene_biotype: protein_coding
description:
  3-methylcrotonyl-CoA carboxylase subunit alpha; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain.


ensembl_gene_id: KS2013_13
symbol: KS2013_13
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: KS2013_1304
symbol: AOE50018.1
gene_biotype: protein_coding
description:
  Pfam:pfam08328 Adenylosuccinate lyase C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: KS2013_1307
symbol: queH
gene_biotype: protein_coding
description:
  Putative BCR protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: KS2013_131
symbol: engB
gene_biotype: protein_coding
description:
  Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: KS2013_1311
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: KS2013_1312
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: KS2013_1318
symbol: recR
gene_biotype: protein_coding
description:
  Recombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: KS2013_1319
symbol: AOE50033.1
gene_biotype: protein_coding
description:
  Nucleoid-associated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: KS2013_1320
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: KS2013_1323
symbol: rimK
gene_biotype: protein_coding
description:
  Putative alpha-L-glutamate ligase; Pfam:pfam08443 RimK-like ATP-grasp domain; Belongs to the RimK family.


ensembl_gene_id: KS2013_1331
symbol: AOE50045.1
gene_biotype: protein_coding
description:
  Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: KS2013_1332
symbol: AOE50046.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; Pfam:pfam03466 LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: KS2013_1333
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: KS2013_1334
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: KS2013_1335
symbol: AOE50049.1
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: KS2013_1337
symbol: AOE50051.1
gene_biotype: protein_coding
description:
  Pfam:pfam02219 Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: KS2013_1341
symbol: AOE50054.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.


ensembl_gene_id: KS2013_1345
symbol: AOE50058.1
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: KS2013_1349
symbol: AOE50062.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; Pfam:pfam00486 Transcriptional regulatory protein, C terminal.


ensembl_gene_id: KS2013_1353
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: KS2013_1357
symbol: AOE50070.1
gene_biotype: protein_coding
description:
  Peptidase M48 Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: KS2013_136
symbol: AOE48866.1
gene_biotype: protein_coding
description:
  Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: KS2013_1362
symbol: AOE50074.1
gene_biotype: protein_coding
description:
  NAD(P)H-quinone oxidoreductase; Pfam:pfam03358 NADPH-dependent FMN reductase; Belongs to the WrbA family.


ensembl_gene_id: KS2013_1364
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: KS2013_1365
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: KS2013_1367
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: KS2013_1368
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: KS2013_1369
symbol: trpF
gene_biotype: protein_coding
description:
  Indole-3-glycerol-phosphate synthase; Phosphoribosylanthranilate isomerase; Pfam:pfam00218 Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.


ensembl_gene_id: KS2013_1370
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: KS2013_1371
symbol: AOE50083.1
gene_biotype: protein_coding
description:
  Glutamine amidotransferase of anthranilate synthase; Pfam:pfam00117 Glutamine amidotransferase class-I.


ensembl_gene_id: KS2013_138
symbol: AOE48868.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: KS2013_1385
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: KS2013_1387
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: KS2013_1388
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: KS2013_1391
symbol: murJ
gene_biotype: protein_coding
description:
  Putative lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: KS2013_1396
symbol: obg
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: KS2013_1398
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: KS2013_1400
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase ATP; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: KS2013_1403
symbol: AOE50115.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: KS2013_1409
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole synthetase; Pfam:pfam02769 AIR synthase related protein, C-terminal domain.


ensembl_gene_id: KS2013_141
symbol: AOE48871.1
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: KS2013_1410
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: KS2013_1414
symbol: AOE50126.1
gene_biotype: protein_coding
description:
  ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: KS2013_1415
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: KS2013_1422
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex RsxE subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: KS2013_1423
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transporter RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: KS2013_1424
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex subunit C; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: KS2013_1425
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transporter RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: KS2013_1426
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transporter RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: KS2013_1427
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex subunit E; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: KS2013_1428
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: KS2013_1431
symbol: AOE50143.1
gene_biotype: protein_coding
description:
  Putative colanic biosynthesis UDP-glucose lipid carrier transferase; Pfam:pfam02397 Bacterial sugar transferase.


ensembl_gene_id: KS2013_1442
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: KS2013_1443
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; Pfam:pfam01507 Phosphoadenosine phosphosulfate reductase family.


ensembl_gene_id: KS2013_1446
symbol: AOE50158.1
gene_biotype: protein_coding
description:
  Pfam:pfam03808 Glycosyl transferase WecB/TagA/CpsF family; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: KS2013_1454
symbol: AOE50166.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; Pfam:pfam03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: KS2013_1455
symbol: AOE50167.1
gene_biotype: protein_coding
description:
  Pfam:pfam02350 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: KS2013_1456
symbol: wecA
gene_biotype: protein_coding
description:
  Glycosyl transferase family 4; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). Belongs to the glycosyltransferase 4 family. WecA subfamily.


ensembl_gene_id: KS2013_1460
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: KS2013_1461
symbol: rfaH
gene_biotype: protein_coding
description:
  Transcription antitermination protein RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family.


ensembl_gene_id: KS2013_1466
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: KS2013_147
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: KS2013_1474
symbol: AOE50186.1
gene_biotype: protein_coding
description:
  Competence protein ComEA helix-hairpin-helix repeat protein; Pfam:pfam12836 Helix-hairpin-helix motif.


ensembl_gene_id: KS2013_1475
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: KS2013_1476
symbol: lapB
gene_biotype: protein_coding
description:
  TPR repeat-containing protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: KS2013_1478
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: KS2013_1479
symbol: AOE50191.1
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: KS2013_1482
symbol: hisC
gene_biotype: protein_coding
description:
  Pfam:pfam00155 Aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: KS2013_1485
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: KS2013_1486
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: KS2013_1488
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: KS2013_1495
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: KS2013_1498
symbol: AOE50210.1
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: KS2013_1499
symbol: AOE50211.1
gene_biotype: protein_coding
description:
  Rifampin ADP-ribosyl transferase; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: KS2013_15
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: KS2013_150
symbol: AOE48879.1
gene_biotype: protein_coding
description:
  Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: KS2013_1500
symbol: AOE50212.1
gene_biotype: protein_coding
description:
  Pfam:pfam00579 tRNA synthetases class I (W and Y); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: KS2013_1503
symbol: AOE50215.1
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; Pfam:pfam01300 Telomere recombination; Belongs to the SUA5 family.


ensembl_gene_id: KS2013_1505
symbol: AOE50217.1
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: KS2013_1514
symbol: pcm
gene_biotype: protein_coding
description:
  Protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: KS2013_1515
symbol: surE
gene_biotype: protein_coding
description:
  5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: KS2013_1516
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: KS2013_1517
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: KS2013_1518
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: KS2013_1520
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: KS2013_1521
symbol: AOE50231.1
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; Pfam:pfam00117 Glutamine amidotransferase class-I.


ensembl_gene_id: KS2013_1524
symbol: AOE50234.1
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).


ensembl_gene_id: KS2013_1528
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: KS2013_1529
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: KS2013_1530
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: KS2013_1531
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; Pfam:pfam00793 DAHP synthetase I family; Belongs to the KdsA family.


ensembl_gene_id: KS2013_1532
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: KS2013_1533
symbol: AOE50243.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam02639 Uncharacterized BCR, YaiI/YqxD family COG1671; Belongs to the UPF0178 family.


ensembl_gene_id: KS2013_1535
symbol: AOE50245.1
gene_biotype: protein_coding
description:
  (P)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: KS2013_1536
symbol: katG
gene_biotype: protein_coding
description:
  Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: KS2013_1538
symbol: rlmD
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: KS2013_1547
symbol: AOE50257.1
gene_biotype: protein_coding
description:
  Disulfide bond isomerase, periplasmic chaperone activated by DsbD homodimeric; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: KS2013_1548
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: KS2013_1550
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: KS2013_1551
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: KS2013_1552
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: KS2013_1556
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein Srp54; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual co [...]


ensembl_gene_id: KS2013_1568
symbol: pepA
gene_biotype: protein_coding
description:
  Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: KS2013_1572
symbol: valS
gene_biotype: protein_coding
description:
  Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: KS2013_1576
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: KS2013_1578
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine 5''''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: KS2013_1579
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: KS2013_158
symbol: AOE48887.1
gene_biotype: protein_coding
description:
  ABC transporter permease; Pfam:pfam00528 Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: KS2013_1580
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: KS2013_1581
symbol: bamB
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: KS2013_1584
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: KS2013_1587
symbol: rlmN
gene_biotype: protein_coding
description:
  Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: KS2013_1588
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: KS2013_159
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: KS2013_1590
symbol: queC
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: KS2013_1591
symbol: queE
gene_biotype: protein_coding
description:
  7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: KS2013_1592
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: KS2013_1593
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: KS2013_1594
symbol: tolB
gene_biotype: protein_coding
description:
  Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: KS2013_1596
symbol: tolR
gene_biotype: protein_coding
description:
  Biopolymer transporter ExbD; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: KS2013_1597
symbol: tolQ
gene_biotype: protein_coding
description:
  Colicin uptake protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: KS2013_1599
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: KS2013_160
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: KS2013_161
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: KS2013_1616
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: KS2013_1617
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: KS2013_1619
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: KS2013_1623
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: KS2013_1626
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: KS2013_1630
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: KS2013_1631
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: KS2013_1633
symbol: AOE50343.1
gene_biotype: protein_coding
description:
  Methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: KS2013_1641
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: KS2013_1642
symbol: AOE50352.1
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: KS2013_1643
symbol: fabZ
gene_biotype: protein_coding
description:
  3-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: KS2013_1644
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: KS2013_1645
symbol: AOE50355.1
gene_biotype: protein_coding
description:
  Outer membrane chaperone Skp (OmpH); Pfam:pfam03938 Outer membrane protein (OmpH-like); Belongs to the skp family.


ensembl_gene_id: KS2013_1646
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: KS2013_1648
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: KS2013_1650
symbol: uppS
gene_biotype: protein_coding
description:
  UDP diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: KS2013_1651
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: KS2013_1653
symbol: tsf
gene_biotype: protein_coding
description:
  endo-1,4-D-glucanase; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: KS2013_1666
symbol: tpm
gene_biotype: protein_coding
description:
  Pfam:pfam05724 Thiopurine S-methyltransferase (TPMT); Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: KS2013_167
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: KS2013_1672
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: KS2013_1673
symbol: glnD
gene_biotype: protein_coding
description:
  Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: KS2013_1674
symbol: dapD
gene_biotype: protein_coding
description:
  Pfam:pfam14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: KS2013_1677
symbol: AOE50387.1
gene_biotype: protein_coding
description:
  Peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; Pfam:pfam02557 D-alanyl-D-alanine carboxypeptidase.


ensembl_gene_id: KS2013_168
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: KS2013_1683
symbol: acpS
gene_biotype: protein_coding
description:
  4''''-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: KS2013_1684
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5''''-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: KS2013_1686
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: KS2013_1687
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: KS2013_1690
symbol: lepA
gene_biotype: protein_coding
description:
  Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: KS2013_1694
symbol: AOE50404.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor AlgU; Pfam:pfam08281 Sigma-70, region 4; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: KS2013_1698
symbol: AOE50408.1
gene_biotype: protein_coding
description:
  Folate-binding protein YgfZ; Pfam:pfam01571 Aminomethyltransferase folate-binding domain; Belongs to the GcvT family.


ensembl_gene_id: KS2013_1701
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-ACP dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: KS2013_1702
symbol: AOE50412.1
gene_biotype: protein_coding
description:
  Pfam:pfam00109 Beta-ketoacyl synthase, N-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: KS2013_1704
symbol: lysS
gene_biotype: protein_coding
description:
  Lysine--tRNA ligase; Pfam:pfam00152 tRNA synthetases class II (D, K and N); Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: KS2013_1705
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: KS2013_1709
symbol: AOE50419.1
gene_biotype: protein_coding
description:
  Pfam:pfam13361 UvrD-like helicase C-terminal domain; Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: KS2013_171
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: KS2013_1714
symbol: queF
gene_biotype: protein_coding
description:
  NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: KS2013_1715
symbol: rlmM
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase M; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: KS2013_172
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: KS2013_1725
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: KS2013_1733
symbol: AOE50442.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: KS2013_1734
symbol: AOE50443.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: KS2013_1736
symbol: AOE50445.1
gene_biotype: protein_coding
description:
  N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; Pfam:pfam01510 N-acetylmuramoyl-L-alanine amidase.


ensembl_gene_id: KS2013_1737
symbol: AOE50446.1
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide pyrophosphorylase; Pfam:pfam01729 Quinolinate phosphoribosyl transferase, C-terminal domain; Belongs to the NadC/ModD family.


ensembl_gene_id: KS2013_1738
symbol: zapD
gene_biotype: protein_coding
description:
  Cell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: KS2013_1739
symbol: coaE
gene_biotype: protein_coding
description:
  Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: KS2013_1740
symbol: AOE50449.1
gene_biotype: protein_coding
description:
  Methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: KS2013_1745
symbol: yacG
gene_biotype: protein_coding
description:
  DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: KS2013_1747
symbol: secA
gene_biotype: protein_coding
description:
  Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: KS2013_1750
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: KS2013_1751
symbol: ftsZ
gene_biotype: protein_coding
description:
  Peptidase M23; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: KS2013_1752
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: KS2013_1753
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: KS2013_1754
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: KS2013_1756
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: KS2013_1757
symbol: ftsW
gene_biotype: protein_coding
description:
  Putative lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: KS2013_1758
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: KS2013_1759
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: KS2013_1760
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: KS2013_1761
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: KS2013_1762
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.


ensembl_gene_id: KS2013_1763
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: KS2013_1764
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: KS2013_1770
symbol: rsmI
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: KS2013_1773
symbol: gmhA
gene_biotype: protein_coding
description:
  DnaA initiator-associating protein DiaA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: KS2013_1776
symbol: AOE50485.1
gene_biotype: protein_coding
description:
  Stringent starvation protein A; Pfam:pfam13417 Glutathione S-transferase, N-terminal domain; Belongs to the GST superfamily.


ensembl_gene_id: KS2013_1778
symbol: AOE50487.1
gene_biotype: protein_coding
description:
  Cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: KS2013_1779
symbol: AOE50488.1
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome C reductase; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: KS2013_1781
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: KS2013_1788
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: KS2013_1792
symbol: AOE50501.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: KS2013_1797
symbol: AOE50506.1
gene_biotype: protein_coding
description:
  Putative PTS IIA-like nitrogen-regulatory protein PtsN; Pfam:pfam00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.


ensembl_gene_id: KS2013_1803
symbol: AOE50512.1
gene_biotype: protein_coding
description:
  Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; Pfam:pfam00795 Carbon-nitrogen hydrolase.


ensembl_gene_id: KS2013_1806
symbol: AOE50515.1
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: KS2013_1807
symbol: AOE50516.1
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: KS2013_1810
symbol: prmC
gene_biotype: protein_coding
description:
  Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: KS2013_1811
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: KS2013_1812
symbol: hemA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: KS2013_1814
symbol: lolB
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: KS2013_1815
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: KS2013_1816
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: KS2013_1817
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: KS2013_1818
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: KS2013_1819
symbol: ychF
gene_biotype: protein_coding
description:
  Ribosome-binding ATPase YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: KS2013_182
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: KS2013_1826
symbol: AOE50535.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam02586 Uncharacterized ACR, COG2135; Belongs to the SOS response-associated peptidase family.


ensembl_gene_id: KS2013_183
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: KS2013_1834
symbol: fabV
gene_biotype: protein_coding
description:
  Putative reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: KS2013_1839
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: KS2013_1840
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: KS2013_1841
symbol: pfp
gene_biotype: protein_coding
description:
  Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: KS2013_1842
symbol: AOE50551.1
gene_biotype: protein_coding
description:
  TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: KS2013_1845
symbol: hppA
gene_biotype: protein_coding
description:
  Potassium transporter; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.


ensembl_gene_id: KS2013_1846
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: KS2013_1848
symbol: AOE50557.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 subunit; Pfam:pfam04542 Sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: KS2013_1853
symbol: AOE50562.1
gene_biotype: protein_coding
description:
  Phospholipase A(1); Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: KS2013_1858
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: KS2013_1863
symbol: AOE50572.1
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: KS2013_1864
symbol: AOE50573.1
gene_biotype: protein_coding
description:
  DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: KS2013_187
symbol: trmH
gene_biotype: protein_coding
description:
  tRNA methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: KS2013_1874
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: KS2013_1877
symbol: AOE50586.1
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: KS2013_1880
symbol: rlmB
gene_biotype: protein_coding
description:
  23S rRNA (guanosine-2''''-O-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: KS2013_1881
symbol: rnr
gene_biotype: protein_coding
description:
  Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: KS2013_1883
symbol: hldE
gene_biotype: protein_coding
description:
  Heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: KS2013_1886
symbol: AOE50595.1
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Pfam:pfam04055 Radical SAM superfamily; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: KS2013_189
symbol: AOE48917.1
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: KS2013_1891
symbol: AOE50600.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase accessory protein CcoG; Pfam:pfam11614 IG-like fold at C-terminal of FixG, putative oxidoreductase.


ensembl_gene_id: KS2013_1895
symbol: AOE50604.1
gene_biotype: protein_coding
description:
  Pfam:pfam00115 Cytochrome C and Quinol oxidase polypeptide I; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: KS2013_1897
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: KS2013_190
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: KS2013_1900
symbol: AOE50609.1
gene_biotype: protein_coding
description:
  Pfam:pfam00764 Arginosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: KS2013_1901
symbol: AOE50610.1
gene_biotype: protein_coding
description:
  Pfam:pfam02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: KS2013_1906
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: KS2013_1910
symbol: hflX
gene_biotype: protein_coding
description:
  GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: KS2013_1911
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: KS2013_1912
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: KS2013_1913
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: KS2013_1916
symbol: nnrD
gene_biotype: protein_coding
description:
  Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]


ensembl_gene_id: KS2013_1917
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: KS2013_1918
symbol: AOE50627.1
gene_biotype: protein_coding
description:
  Putative pterin-4-alpha-carbinolamine dehydratase; Pfam:pfam01329 Pterin 4 alpha carbinolamine dehydratase.


ensembl_gene_id: KS2013_1919
symbol: rsgA
gene_biotype: protein_coding
description:
  Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: KS2013_192
symbol: AOE48920.1
gene_biotype: protein_coding
description:
  Pfam:pfam10070 Uncharacterized protein conserved in bacteria (DUF2309); Belongs to the UPF0753 family.


ensembl_gene_id: KS2013_1921
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: KS2013_1925
symbol: AOE50634.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, TraR/DksA family; Pfam:pfam01258 Prokaryotic dksA/traR C4-type zinc finger.


ensembl_gene_id: KS2013_1929
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: KS2013_194
symbol: AOE48922.1
gene_biotype: protein_coding
description:
  Pfam:pfam00126 Bacterial regulatory helix-turn-helix protein, lysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: KS2013_1942
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: KS2013_1943
symbol: AOE50652.1
gene_biotype: protein_coding
description:
  Farnesyl-diphosphate synthase; Pfam:pfam00348 Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: KS2013_1944
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: KS2013_1945
symbol: AOE50654.1
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: KS2013_1946
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: KS2013_1947
symbol: nusB
gene_biotype: protein_coding
description:
  N utilization substance protein B-like protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: KS2013_1948
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: KS2013_1949
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: KS2013_1951
symbol: AOE50660.1
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: KS2013_1952
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: KS2013_1953
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: KS2013_196
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: KS2013_1960
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: KS2013_1961
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: KS2013_1962
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: KS2013_1963
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: KS2013_1965
symbol: secY
gene_biotype: protein_coding
description:
  Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: KS2013_1966
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: KS2013_1968
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: KS2013_1969
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: KS2013_1970
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: KS2013_1971
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: KS2013_1972
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: KS2013_1973
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: KS2013_1974
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: KS2013_1975
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: KS2013_1976
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: KS2013_1978
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: KS2013_1979
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: KS2013_198
symbol: AOE48926.1
gene_biotype: protein_coding
description:
  Malonic semialdehyde reductase; Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: KS2013_1980
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: KS2013_1981
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: KS2013_1982
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: KS2013_1983
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: KS2013_1985
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: KS2013_1986
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: KS2013_1988
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: KS2013_1989
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: KS2013_1990
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: KS2013_1991
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: KS2013_1992
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: KS2013_1993
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta'''; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: KS2013_1994
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: KS2013_1995
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: KS2013_1996
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: KS2013_1997
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: KS2013_1998
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: KS2013_1999
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: KS2013_2
symbol: KS2013_2
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: KS2013_2000
symbol: secE
gene_biotype: protein_coding
description:
  Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: KS2013_2002
symbol: coaX
gene_biotype: protein_coding
description:
  Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: KS2013_2003
symbol: birA
gene_biotype: protein_coding
description:
  Biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: KS2013_2006
symbol: deaD
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: KS2013_2010
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: KS2013_2012
symbol: anmK
gene_biotype: protein_coding
description:
  Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: KS2013_2014
symbol: erpA
gene_biotype: protein_coding
description:
  Iron--sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: KS2013_202
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: KS2013_2021
symbol: msrA-2
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: KS2013_2024
symbol: AOE50729.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; Pfam:pfam08281 Sigma-70, region 4; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: KS2013_2033
symbol: AOE50738.1
gene_biotype: protein_coding
description:
  2-hydroxymuconic semialdehyde dehydrogenase; Pfam:pfam00171 Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: KS2013_2037
symbol: nbaC
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.


ensembl_gene_id: KS2013_2040
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: KS2013_2041
symbol: kmo
gene_biotype: protein_coding
description:
  Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.


ensembl_gene_id: KS2013_2044
symbol: AOE50749.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: KS2013_2045
symbol: AOE50750.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: KS2013_2047
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: KS2013_2051
symbol: sfsA
gene_biotype: protein_coding
description:
  XRE family transcriptional regulator; Pfam:pfam03749 Sugar fermentation stimulation protein; Belongs to the SfsA family.


ensembl_gene_id: KS2013_2052
symbol: dksA
gene_biotype: protein_coding
description:
  Molecular chaperone DnaK; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: KS2013_2053
symbol: gluQ
gene_biotype: protein_coding
description:
  Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: KS2013_2054
symbol: pcnB
gene_biotype: protein_coding
description:
  Poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: KS2013_2055
symbol: AOE50760.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Pfam:pfam01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK).


ensembl_gene_id: KS2013_2057
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: KS2013_2058
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: KS2013_2059
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: KS2013_2070
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: KS2013_2071
symbol: lipB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: KS2013_2075
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: KS2013_2077
symbol: mrdB
gene_biotype: protein_coding
description:
  Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: KS2013_2078
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: KS2013_2079
symbol: rlmH
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: KS2013_2080
symbol: rsfS
gene_biotype: protein_coding
description:
  Ribosome-associated protein IOJAP; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: KS2013_2081
symbol: nadD
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: KS2013_2083
symbol: lptE
gene_biotype: protein_coding
description:
  LPS-assembly lipoprotein LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: KS2013_2084
symbol: leuS
gene_biotype: protein_coding
description:
  Pfam:pfam13603 Leucyl-tRNA synthetase, Domain 2; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: KS2013_2085
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: KS2013_2087
symbol: ybeY
gene_biotype: protein_coding
description:
  Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: KS2013_2089
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: KS2013_2094
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: KS2013_2095
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: KS2013_2097
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: KS2013_2098
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: KS2013_2099
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: KS2013_210
symbol: AOE48938.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; Pfam:pfam04542 Sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: KS2013_2101
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: KS2013_2102
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: KS2013_2103
symbol: AOE50808.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit M; Pfam:pfam00361 NADH-Ubiquinone/plastoquinone (complex I), various chains.


ensembl_gene_id: KS2013_2104
symbol: AOE50809.1
gene_biotype: protein_coding
description:
  Proton-translocating NADH-quinone oxidoreductase, chain L; Pfam:pfam00361 NADH-Ubiquinone/plastoquinone (complex I), various chains.


ensembl_gene_id: KS2013_2105
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: KS2013_2106
symbol: AOE50811.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: KS2013_2107
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: KS2013_2108
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: KS2013_2109
symbol: AOE50814.1
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: KS2013_2110
symbol: AOE50815.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: KS2013_2112
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: KS2013_2113
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: KS2013_2114
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: KS2013_2115
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: KS2013_212
symbol: bamE
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor BamE; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: KS2013_2122
symbol: AOE50827.1
gene_biotype: protein_coding
description:
  Cytochrome oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: KS2013_2123
symbol: AOE50828.1
gene_biotype: protein_coding
description:
  Cytochrome B559 subunit alpha; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: KS2013_2131
symbol: groL
gene_biotype: protein_coding
description:
  Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: KS2013_2132
symbol: groS
gene_biotype: protein_coding
description:
  10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: KS2013_2135
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: KS2013_2137
symbol: AOE50842.1
gene_biotype: protein_coding
description:
  DNA-binding heavy metal response regulator, putative; Pfam:pfam00072 Response regulator receiver domain.


ensembl_gene_id: KS2013_2138
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: KS2013_2139
symbol: AOE50844.1
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: KS2013_2140
symbol: AOE50845.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: KS2013_2142
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: KS2013_2144
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: KS2013_2145
symbol: AOE50850.1
gene_biotype: protein_coding
description:
  Pfam:pfam02954 Bacterial regulatory protein, Fis family; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: KS2013_2147
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; Pfam:pfam01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Belongs to the GARS family.


ensembl_gene_id: KS2013_2152
symbol: AOE50857.1
gene_biotype: protein_coding
description:
  AAA ATPase central domain protein; Pfam:pfam00004 ATPase family associated with various cellular activities (AAA).


ensembl_gene_id: KS2013_2153
symbol: coq7
gene_biotype: protein_coding
description:
  2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: KS2013_2156
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: KS2013_2157
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: KS2013_2159
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: KS2013_2160
symbol: AOE50865.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: KS2013_2169
symbol: gshB
gene_biotype: protein_coding
description:
  Pfam:pfam02955 Prokaryotic glutathione synthetase, ATP-grasp domain; Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: KS2013_2171
symbol: AOE50876.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam02622 Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: KS2013_2172
symbol: AOE50877.1
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: KS2013_2175
symbol: AOE50880.1
gene_biotype: protein_coding
description:
  Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: KS2013_2176
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: KS2013_2179
symbol: AOE50884.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: KS2013_218
symbol: nadK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: KS2013_2180
symbol: AOE50885.1
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: KS2013_2182
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: KS2013_2185
symbol: AOE50890.1
gene_biotype: protein_coding
description:
  Iron transporter; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: KS2013_2189
symbol: AOE50894.1
gene_biotype: protein_coding
description:
  LysR family transcriptional regulator; Pfam:pfam03466 LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: KS2013_219
symbol: hrcA
gene_biotype: protein_coding
description:
  HrcA family transcriptional regulator; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: KS2013_220
symbol: grpE
gene_biotype: protein_coding
description:
  Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: KS2013_2229
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfurtransferase; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: KS2013_224
symbol: dnaJ
gene_biotype: protein_coding
description:
  Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]


ensembl_gene_id: KS2013_225
symbol: purK
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: KS2013_2257
symbol: rsmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase J; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: KS2013_226
symbol: purE
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: KS2013_2260
symbol: AOE50964.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase D; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: KS2013_2261
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: KS2013_2263
symbol: AOE50967.1
gene_biotype: protein_coding
description:
  Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: KS2013_2265
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: KS2013_2270
symbol: acpP-2
gene_biotype: protein_coding
description:
  Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: KS2013_2277
symbol: AOE50981.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: KS2013_228
symbol: dapB
gene_biotype: protein_coding
description:
  4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: KS2013_2281
symbol: AOE50985.1
gene_biotype: protein_coding
description:
  Pfam:pfam02801 Beta-ketoacyl synthase, C-terminal domain; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: KS2013_2286
symbol: ubiD
gene_biotype: protein_coding
description:
  3-polyprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: KS2013_2289
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: KS2013_2291
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: KS2013_2298
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: KS2013_2299
symbol: tsaC
gene_biotype: protein_coding
description:
  Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: KS2013_230
symbol: carB
gene_biotype: protein_coding
description:
  Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain; Belongs to the CarB family.


ensembl_gene_id: KS2013_2301
symbol: AOE51005.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: KS2013_2306
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: KS2013_2307
symbol: fmt
gene_biotype: protein_coding
description:
  Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: KS2013_2308
symbol: AOE51012.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: KS2013_231
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: KS2013_2314
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: KS2013_2315
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: KS2013_2317
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: KS2013_2318
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: KS2013_2319
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: KS2013_2320
symbol: atpA
gene_biotype: protein_coding
description:
  ATP F0F1 synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: KS2013_2321
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: KS2013_2322
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: KS2013_2323
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: KS2013_2324
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: KS2013_2326
symbol: AOE51030.1
gene_biotype: protein_coding
description:
  Chromosome partitioning protein ParB; Pfam:pfam02195 ParB-like nuclease domain; Belongs to the ParB family.


ensembl_gene_id: KS2013_2328
symbol: rsmG
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: KS2013_2329
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: KS2013_2333
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: KS2013_2334
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: KS2013_2335
symbol: AOE51039.1
gene_biotype: protein_coding
description:
  Putative membrane protein insertion efficiency factor; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: KS2013_2336
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: KS2013_245
symbol: AOE48973.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; Pfam:pfam00072 Response regulator receiver domain.


ensembl_gene_id: KS2013_247
symbol: rlmE
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: KS2013_248
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: KS2013_249
symbol: AOE48977.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: KS2013_250
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: KS2013_254
symbol: AOE48982.1
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: KS2013_255
symbol: nqrF
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: KS2013_256
symbol: nqrE
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: KS2013_257
symbol: nqrD
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: KS2013_258
symbol: nqrC
gene_biotype: protein_coding
description:
  Hypothetical protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: KS2013_259
symbol: nqrB
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: KS2013_260
symbol: nqrA
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: KS2013_261
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: KS2013_262
symbol: AOE48990.1
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: KS2013_266
symbol: kdkA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: KS2013_272
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: KS2013_285
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: KS2013_289
symbol: AOE49016.1
gene_biotype: protein_coding
description:
  33 kDa chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: KS2013_290
symbol: AOE49017.1
gene_biotype: protein_coding
description:
  Ribosome-associated heat shock protein Hsp15; Pfam:pfam01479 S4 domain; Belongs to the HSP15 family.


ensembl_gene_id: KS2013_293
symbol: AOE49020.1
gene_biotype: protein_coding
description:
  General secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: KS2013_3
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: KS2013_300
symbol: AOE49026.1
gene_biotype: protein_coding
description:
  Type II secretion system protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: KS2013_301
symbol: AOE49027.1
gene_biotype: protein_coding
description:
  Type II secretion system protein M; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: KS2013_313
symbol: AOE49039.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase, F subunit; Pfam:pfam07992 Pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: KS2013_314
symbol: AOE49040.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: KS2013_317
symbol: AOE49043.1
gene_biotype: protein_coding
description:
  Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: KS2013_318
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: KS2013_319
symbol: gpsA
gene_biotype: protein_coding
description:
  Pfam:pfam07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: KS2013_320
symbol: trmL
gene_biotype: protein_coding
description:
  rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: KS2013_321
symbol: AOE49047.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, Fis family; Pfam:pfam00072 Response regulator receiver domain.


ensembl_gene_id: KS2013_322
symbol: AOE49048.1
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, nitrogen specific, NtrB; Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.


ensembl_gene_id: KS2013_327
symbol: AOE49053.1
gene_biotype: protein_coding
description:
  SirA family protein; Pfam:pfam01206 Sulfurtransferase TusA; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: KS2013_332
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: KS2013_337
symbol: AOE49062.1
gene_biotype: protein_coding
description:
  RND efflux system, outer membrane lipoprotein, NodT family; Pfam:pfam02321 Outer membrane efflux protein.


ensembl_gene_id: KS2013_339
symbol: AOE49064.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Pfam:pfam00529 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: KS2013_343
symbol: tatC
gene_biotype: protein_coding
description:
  Twin-arginine protein translocation system subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: KS2013_344
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: KS2013_345
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: KS2013_347
symbol: ubiB
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: KS2013_349
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: KS2013_350
symbol: AOE49075.1
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Pfam:pfam06155 Protein of unknown function (DUF971).


ensembl_gene_id: KS2013_352
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: KS2013_353
symbol: hslV
gene_biotype: protein_coding
description:
  Peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: KS2013_356
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: KS2013_369
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: KS2013_370
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: KS2013_372
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: KS2013_375
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: KS2013_381
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: KS2013_385
symbol: AOE49110.1
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: KS2013_386
symbol: AOE49111.1
gene_biotype: protein_coding
description:
  Phosphomannomutase; Pfam:pfam02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I.


ensembl_gene_id: KS2013_387
symbol: slmA
gene_biotype: protein_coding
description:
  TetR family transcriptional regulator; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: KS2013_389
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: KS2013_392
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: KS2013_393
symbol: surA
gene_biotype: protein_coding
description:
  Chaperone SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: KS2013_394
symbol: lptD
gene_biotype: protein_coding
description:
  LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: KS2013_397
symbol: djlA
gene_biotype: protein_coding
description:
  Heat shock protein DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: KS2013_4
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: KS2013_400
symbol: cobB
gene_biotype: protein_coding
description:
  NAD-dependent protein deacylase; Pfam:pfam02146 Sir2 family; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: KS2013_409
symbol: AOE49133.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Pfam:pfam13437 HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: KS2013_410
symbol: AOE49134.1
gene_biotype: protein_coding
description:
  Acriflavine resistance protein B; Pfam:pfam00873 AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: KS2013_417
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: KS2013_418
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: KS2013_422
symbol: tsaD
gene_biotype: protein_coding
description:
  tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: KS2013_424
symbol: plsY
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: KS2013_425
symbol: AOE49149.1
gene_biotype: protein_coding
description:
  Dihydroneopterin triphosphate 2''''-epimerase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: KS2013_430
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: KS2013_431
symbol: cca
gene_biotype: protein_coding
description:
  Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: KS2013_435
symbol: AOE49159.1
gene_biotype: protein_coding
description:
  RNA methylase, NOL1/NOP2/sun family; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.


ensembl_gene_id: KS2013_436
symbol: AOE49160.1
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: KS2013_443
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: KS2013_446
symbol: nfuA
gene_biotype: protein_coding
description:
  Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: KS2013_454
symbol: ung
gene_biotype: protein_coding
description:
  Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: KS2013_457
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: KS2013_458
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: KS2013_459
symbol: bioH
gene_biotype: protein_coding
description:
  Pimeloyl-[acyl-carrier protein] methyl ester esterase; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: KS2013_460
symbol: bioC
gene_biotype: protein_coding
description:
  Malonyl-[acyl-carrier protein] O-methyltransferase; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: KS2013_462
symbol: bioD
gene_biotype: protein_coding
description:
  ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: KS2013_469
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: KS2013_477
symbol: uvrA
gene_biotype: protein_coding
description:
  UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: KS2013_479
symbol: AOE49203.1
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: KS2013_480
symbol: AOE49204.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Pfam:pfam01027 Inhibitor of apoptosis-promoting Bax1; Belongs to the BI1 family.


ensembl_gene_id: KS2013_484
symbol: AOE49208.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease; Pfam:pfam00528 Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: KS2013_485
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: KS2013_488
symbol: AOE49212.1
gene_biotype: protein_coding
description:
  PAS/PAC sensor signal transduction histidine kinase; Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.


ensembl_gene_id: KS2013_490
symbol: AOE49214.1
gene_biotype: protein_coding
description:
  Anti-sigma factor antagonist; Pfam:pfam01740 STAS domain; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: KS2013_493
symbol: AOE49217.1
gene_biotype: protein_coding
description:
  Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.


ensembl_gene_id: KS2013_498
symbol: AOE49222.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; Pfam:pfam03466 LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: KS2013_500
symbol: AOE49224.1
gene_biotype: protein_coding
description:
  Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: KS2013_516
symbol: AOE49240.1
gene_biotype: protein_coding
description:
  Pfam:pfam00474 Sodium:solute symporter family; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: KS2013_527
symbol: AOE49251.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: KS2013_531
symbol: AOE49255.1
gene_biotype: protein_coding
description:
  Nitrite reductase, copper-containing; Pfam:pfam00034 Cytochrome c; Belongs to the multicopper oxidase family.


ensembl_gene_id: KS2013_541
symbol: AOE49265.1
gene_biotype: protein_coding
description:
  Integrase; Pfam:pfam13356 Domain of unknown function (DUF4102); Belongs to the 'phage' integrase family.


ensembl_gene_id: KS2013_546
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: KS2013_549
symbol: AOE49273.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: KS2013_554
symbol: cpdA
gene_biotype: protein_coding
description:
  3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: KS2013_555
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: KS2013_556
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: KS2013_562
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: KS2013_582
symbol: fabH-2
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: KS2013_589
symbol: AOE49313.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; Pfam:pfam00106 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: KS2013_597
symbol: AOE49321.1
gene_biotype: protein_coding
description:
  Fatty-acid oxidation protein subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: KS2013_609
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: KS2013_61
symbol: KS2013_61
gene_biotype: protein_coding
description:
  Putative nucleoside-diphosphate-sugar epimerase; Pfam:pfam08547 Complex I intermediate-associated protein 30 (CIA30).


ensembl_gene_id: KS2013_610
symbol: AOE49334.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: KS2013_611
symbol: cysS
gene_biotype: protein_coding
description:
  Pfam:pfam01406 tRNA synthetases class I (C) catalytic domain; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: KS2013_615
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: KS2013_616
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: KS2013_617
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: KS2013_620
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: KS2013_621
symbol: lon
gene_biotype: protein_coding
description:
  Peptidase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: KS2013_622
symbol: AOE49346.1
gene_biotype: protein_coding
description:
  Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: KS2013_625
symbol: AOE49349.1
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; Pfam:pfam00005 ABC transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: KS2013_626
symbol: AOE49350.1
gene_biotype: protein_coding
description:
  Peptide ABC transporter; Pfam:pfam00528 Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: KS2013_627
symbol: AOE49351.1
gene_biotype: protein_coding
description:
  Peptide ABC transporter permease; Pfam:pfam00528 Binding-protein-dependent transport system inner membrane component.


ensembl_gene_id: KS2013_630
symbol: AOE49354.1
gene_biotype: protein_coding
description:
  TonB system biopolymer transport component, putative; Pfam:pfam11932 Protein of unknown function (DUF3450).


ensembl_gene_id: KS2013_642
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: KS2013_645
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: KS2013_652
symbol: AOE49376.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase (Quinone); Pfam:pfam00361 NADH-Ubiquinone/plastoquinone (complex I), various chains.


ensembl_gene_id: KS2013_664
symbol: AOE49388.1
gene_biotype: protein_coding
description:
  Proton/glutamate symport protein; Pfam:pfam00375 Sodium:dicarboxylate symporter family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: KS2013_667
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: KS2013_668
symbol: astD
gene_biotype: protein_coding
description:
  N-succinylglutamate 5-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: KS2013_670
symbol: argD
gene_biotype: protein_coding
description:
  Pfam:pfam00202 Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: KS2013_675
symbol: topA
gene_biotype: protein_coding
description:
  Topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoi [...]


ensembl_gene_id: KS2013_676
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: KS2013_677
symbol: rlmL
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase K/L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: KS2013_682
symbol: AOE49406.1
gene_biotype: protein_coding
description:
  Pyruvate carboxyltransferase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).


ensembl_gene_id: KS2013_684
symbol: AOE49408.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: KS2013_686
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: KS2013_69
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: KS2013_690
symbol: mltF
gene_biotype: protein_coding
description:
  Transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: KS2013_691
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: KS2013_693
symbol: AOE49417.1
gene_biotype: protein_coding
description:
  FG-GAP repeat-containing protein; Pfam:pfam13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella.


ensembl_gene_id: KS2013_697
symbol: gshA
gene_biotype: protein_coding
description:
  Pfam:pfam04262 Glutamate-cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: KS2013_698
symbol: AOE49422.1
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: KS2013_715
symbol: AOE49439.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam00675 Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.


ensembl_gene_id: KS2013_717
symbol: AOE49441.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam06167 Glucose-regulated metallo-peptidase M90; Belongs to the MtfA family.


ensembl_gene_id: KS2013_72
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: KS2013_720
symbol: AOE49444.1
gene_biotype: protein_coding
description:
  Pyridoxal-5'-phosphate-dependent protein beta subunit; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.


ensembl_gene_id: KS2013_724
symbol: speE-2
gene_biotype: protein_coding
description:
  Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.


ensembl_gene_id: KS2013_726
symbol: AOE49450.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: KS2013_73
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: KS2013_730
symbol: AOE49454.1
gene_biotype: protein_coding
description:
  Extradiol ring-cleavage dioxygenase; Pfam:pfam02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase.


ensembl_gene_id: KS2013_738
symbol: AOE49462.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: KS2013_739
symbol: AOE49463.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: KS2013_740
symbol: AOE49464.1
gene_biotype: protein_coding
description:
  Iron ABC transporter ATP-binding protein; Pfam:pfam00005 ABC transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: KS2013_744
symbol: AOE49468.1
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: KS2013_763
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: KS2013_77
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: KS2013_777
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: KS2013_778
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: KS2013_78
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: KS2013_780
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: KS2013_781
symbol: pheS
gene_biotype: protein_coding
description:
  Phenylalanine--tRNA ligase alpha subunit; Pfam:pfam01409 tRNA synthetases class II core domain (F); Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: KS2013_782
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanine--tRNA ligase beta subunit; Pfam:pfam03483 B3/4 domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: KS2013_783
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: KS2013_795
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: KS2013_796
symbol: AOE49520.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Pfam:pfam01066 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: KS2013_808
symbol: AOE49531.1
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase-like protein; Pfam:pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.


ensembl_gene_id: KS2013_809
symbol: AOE49532.1
gene_biotype: protein_coding
description:
  Subtilisin-like serine protease-like protein; Pfam:pfam00082 Subtilase family; Belongs to the peptidase S8 family.


ensembl_gene_id: KS2013_81
symbol: glpE
gene_biotype: protein_coding
description:
  Rhodanese domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: KS2013_811
symbol: AOE49534.1
gene_biotype: protein_coding
description:
  B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: KS2013_813
symbol: AOE49536.1
gene_biotype: protein_coding
description:
  Pfam:pfam01923 Cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: KS2013_820
symbol: AOE49543.1
gene_biotype: protein_coding
description:
  Sugar kinase; Pfam:pfam00294 pfkB family carbohydrate kinase; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: KS2013_822
symbol: AOE49545.1
gene_biotype: protein_coding
description:
  Pfam:pfam01553 Acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: KS2013_823
symbol: prmB
gene_biotype: protein_coding
description:
  50S ribosomal protein L3 glutamine methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: KS2013_827
symbol: AOE49550.1
gene_biotype: protein_coding
description:
  Potassium transporter; Pfam:pfam00999 Sodium/hydrogen exchanger family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: KS2013_829
symbol: AOE49551.1
gene_biotype: protein_coding
description:
  tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: KS2013_83
symbol: ubiC
gene_biotype: protein_coding
description:
  Putative chorismate pyruvate-lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: KS2013_831
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: KS2013_839
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: KS2013_840
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: KS2013_842
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: KS2013_843
symbol: AOE49565.1
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis ATP-binding export protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.


ensembl_gene_id: KS2013_844
symbol: AOE49566.1
gene_biotype: protein_coding
description:
  Cytochrome C biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: KS2013_845
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: KS2013_846
symbol: AOE49568.1
gene_biotype: protein_coding
description:
  Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: KS2013_847
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome C biogenesis protein CcmC; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: KS2013_859
symbol: AOE49581.1
gene_biotype: protein_coding
description:
  Pfam:pfam03313 Serine dehydratase alpha chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: KS2013_86
symbol: KS2013_86
gene_biotype: protein_coding
description:
  Pyridoxal-dependent decarboxylase, exosortase system type 1 associated; Pfam:pfam02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain; Belongs to the Orn/Lys/Arg decarboxylase class-II family.


ensembl_gene_id: KS2013_862
symbol: AOE49584.1
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: KS2013_863
symbol: prpB
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: KS2013_865
symbol: AOE49587.1
gene_biotype: protein_coding
description:
  2-methylisocitrate dehydratase, Fe/S-dependent; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.


ensembl_gene_id: KS2013_87
symbol: KS2013_87
gene_biotype: protein_coding
description:
  Acyl-CoA ligase (AMP-forming), exosortase system type 1 associated; Pfam:pfam00501 AMP-binding enzyme.


ensembl_gene_id: KS2013_892
symbol: srkA
gene_biotype: protein_coding
description:
  Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: KS2013_899
symbol: AOE49621.1
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: KS2013_91
symbol: KS2013_91
gene_biotype: protein_coding
description:
  Pfam:pfam00834 Ribulose-phosphate 3 epimerase family; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: KS2013_921
symbol: AOE49643.1
gene_biotype: protein_coding
description:
  Aldolase; Pfam:pfam03328 HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: KS2013_923
symbol: AOE49645.1
gene_biotype: protein_coding
description:
  Citryl-CoA lyase; Pfam:pfam03328 HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: KS2013_927
symbol: AOE49649.1
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; Pfam:pfam00873 AcrB/AcrD/AcrF family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: KS2013_939
symbol: AOE49661.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pfam:pfam14402 7 transmembrane helices usually fused to an inactive transglutaminase.


ensembl_gene_id: KS2013_940
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 2 3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: KS2013_942
symbol: AOE49664.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, cytochrome b556 subunit; Pfam:pfam01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit.


ensembl_gene_id: KS2013_943
symbol: AOE49665.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: KS2013_944
symbol: AOE49666.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase flavoprotein subunit; Pfam:pfam00890 FAD binding domain; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: KS2013_945
symbol: AOE49667.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase iron-sulfur subunit; Pfam:pfam13085 2Fe-2S iron-sulfur cluster binding domain; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: KS2013_947
symbol: AOE49669.1
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: KS2013_948
symbol: sucC
gene_biotype: protein_coding
description:
  Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: KS2013_949
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: KS2013_957
symbol: AOE49678.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, histidine utilization repressor, GntR family; Pfam:pfam07702 UTRA domain.


ensembl_gene_id: KS2013_972
symbol: AOE49693.1
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: KS2013_977
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: KS2013_98
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: KS2013_980
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: KS2013_981
symbol: AOE49702.1
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: KS2013_982
symbol: AOE49703.1
gene_biotype: protein_coding
description:
  Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: KS2013_983
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone protein HscB-like protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: KS2013_984
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: KS2013_989
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: KS2013_990
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: KS2013_994
symbol: AOE49715.1
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue (2-methylpropanoyl) transferase; Pfam:pfam00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain).


ensembl_gene_id: KS2013_995
symbol: AOE49716.1
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase subunit beta; Pfam:pfam02779 Transketolase, pyrimidine binding domain.


ensembl_gene_id: KS2013_996
symbol: pdhA
gene_biotype: protein_coding
description:
  ABC transporter permease; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


