# geneInfo

ensembl_gene_id: B446_00095
symbol: AGS66863.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen.


ensembl_gene_id: B446_00135
symbol: AGS66869.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: B446_00215
symbol: AGS66885.1
gene_biotype: protein_coding
description:
  Putative AraC family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: B446_00220
symbol: AGS66886.1
gene_biotype: protein_coding
description:
  Putative aldo/keto reductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: B446_00225
symbol: AGS66887.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_00350
symbol: AGS66910.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: B446_00435
symbol: AGS66927.1
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: B446_00450
symbol: AGS66930.1
gene_biotype: protein_coding
description:
  Orn/DAP/Arg decarboxylase 2; COG0019 Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.


ensembl_gene_id: B446_00480
symbol: AGS66936.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: B446_00490
symbol: AGS66938.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: B446_00495
symbol: AGS66939.1
gene_biotype: protein_coding
description:
  Cyclophilin type peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: B446_00505
symbol: AGS66941.1
gene_biotype: protein_coding
description:
  Sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: B446_00550
symbol: AGS66950.1
gene_biotype: protein_coding
description:
  Putative regulatory protein; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).


ensembl_gene_id: B446_00590
symbol: AGS66958.1
gene_biotype: protein_coding
description:
  Endoglycoceramidase; COG2730 Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: B446_00625
symbol: mca
gene_biotype: protein_coding
description:
  Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.


ensembl_gene_id: B446_00645
symbol: AGS66969.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: B446_00690
symbol: AGS66978.1
gene_biotype: protein_coding
description:
  TrkA-N domain-containing protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: B446_00725
symbol: AGS66983.1
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: B446_00735
symbol: AGS66985.1
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: B446_00780
symbol: stcT
gene_biotype: protein_coding
description:
  Daunorubicin resistance ABC transporter ATPase subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: B446_00785
symbol: stcL
gene_biotype: protein_coding
description:
  Type IV lanthipeptide synthetase; Involved in the biosynthesis of the lanthipeptide streptocollin; COG0515 Serine/threonine protein kinase.


ensembl_gene_id: B446_00855
symbol: AGS67009.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: B446_00860
symbol: AGS67010.1
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; COG3409 Putative peptidoglycan-binding domain-containing protein.


ensembl_gene_id: B446_00920
symbol: AGS67022.1
gene_biotype: protein_coding
description:
  COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: B446_00925
symbol: AGS67023.1
gene_biotype: protein_coding
description:
  Condensation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: B446_01010
symbol: AGS67040.1
gene_biotype: protein_coding
description:
  Sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: B446_01015
symbol: AGS67041.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: B446_01020
symbol: AGS67042.1
gene_biotype: protein_coding
description:
  ECF sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: B446_01060
symbol: AGS67050.1
gene_biotype: protein_coding
description:
  Allophanate hydrolase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases.


ensembl_gene_id: B446_01155
symbol: AGS67069.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_01175
symbol: AGS67071.1
gene_biotype: protein_coding
description:
  Putative LysR family transcriptional regulator; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: B446_01180
symbol: AGS67072.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: B446_01215
symbol: AGS67079.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: B446_01250
symbol: AGS67086.1
gene_biotype: protein_coding
description:
  UDP-glucuronosyl/UDP-glucosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: B446_01285
symbol: AGS67093.1
gene_biotype: protein_coding
description:
  Mannossyltransferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: B446_01305
symbol: AGS67097.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain-containing protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.


ensembl_gene_id: B446_01335
symbol: AGS67103.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: B446_01350
symbol: AGS67106.1
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_01385
symbol: AGS67113.1
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: B446_01400
symbol: AGS67116.1
gene_biotype: protein_coding
description:
  Glutathione-dependent formaldehyde dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: B446_01410
symbol: AGS67118.1
gene_biotype: protein_coding
description:
  Glutathione-independent formaldehyde dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: B446_01445
symbol: AGS67123.1
gene_biotype: protein_coding
description:
  Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipinsynthase-like protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: B446_01480
symbol: AGS67130.1
gene_biotype: protein_coding
description:
  Amino acid adenylation protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: B446_01525
symbol: AGS67139.1
gene_biotype: protein_coding
description:
  Amino acid adenylation protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: B446_01555
symbol: AGS67145.1
gene_biotype: protein_coding
description:
  GHMP kinase; COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase.


ensembl_gene_id: B446_01585
symbol: kirHVI
gene_biotype: protein_coding
description:
  Putative dioxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: B446_01590
symbol: kirN
gene_biotype: protein_coding
description:
  Crotonyl CoA carboxylase/reductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: B446_01630
symbol: kirHII
gene_biotype: protein_coding
description:
  Protein of unknown function putatively involved in kirromycin biosynthesis or resistance; COG3860 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: B446_01635
symbol: kirCII
gene_biotype: protein_coding
description:
  Acyltransferase; COG3321 Polyketide synthase modules and related proteins; KirCII has specificity for ethylmalonyl-CoA, which is selectively transferred to ACP5 of KirAII.


ensembl_gene_id: B446_01645
symbol: kirD
gene_biotype: protein_coding
description:
  L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: B446_01685
symbol: kirAIII
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthetase-polyketide synthase hybrid; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: B446_01700
symbol: kirP
gene_biotype: protein_coding
description:
  COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: B446_01725
symbol: AGS67177.1
gene_biotype: protein_coding
description:
  N-acetylglucosaminyltransferase; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.


ensembl_gene_id: B446_01730
symbol: AGS67178.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein CapD; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: B446_01830
symbol: AGS67198.1
gene_biotype: protein_coding
description:
  Two-component system regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_01845
symbol: AGS67201.1
gene_biotype: protein_coding
description:
  COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: B446_01875
symbol: AGS67207.1
gene_biotype: protein_coding
description:
  Carboxylesterase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_01900
symbol: AGS67212.1
gene_biotype: protein_coding
description:
  Putative large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell; Belongs to the MscL family.


ensembl_gene_id: B446_01985
symbol: AGS67229.1
gene_biotype: protein_coding
description:
  Class V aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: B446_01995
symbol: AGS67231.1
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: B446_02015
symbol: AGS67235.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: B446_02030
symbol: AGS67238.1
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: B446_02045
symbol: AGS67241.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: B446_02075
symbol: gvpA
gene_biotype: protein_coding
description:
  Gas vesicle synthesis-like protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.


ensembl_gene_id: B446_02125
symbol: AGS67257.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase/oxidase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: B446_02150
symbol: AGS67262.1
gene_biotype: protein_coding
description:
  Glycosyl transferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: B446_02205
symbol: AGS67273.1
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: B446_02310
symbol: AGS67294.1
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: B446_02375
symbol: AGS67307.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: B446_02495
symbol: AGS67331.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: B446_02515
symbol: rpsN-2
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: B446_02540
symbol: rpsR-2
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: B446_02680
symbol: AGS67368.1
gene_biotype: protein_coding
description:
  Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: B446_02720
symbol: AGS67376.1
gene_biotype: protein_coding
description:
  Iron-sulfur protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: B446_02735
symbol: AGS67379.1
gene_biotype: protein_coding
description:
  Polyprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: B446_02860
symbol: AGS67404.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_02915
symbol: AGS67415.1
gene_biotype: protein_coding
description:
  Magnesium or manganese-dependent protein phosphatase; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: B446_02955
symbol: msrA
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: B446_02985
symbol: AGS67429.1
gene_biotype: protein_coding
description:
  Hydrolase; COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: B446_03000
symbol: AGS67432.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter ATP-binding protein; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: B446_03005
symbol: AGS67433.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: B446_03020
symbol: AGS67436.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase family protein; COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: B446_03025
symbol: AGS67437.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_03030
symbol: AGS67438.1
gene_biotype: protein_coding
description:
  Integral membrane binding-protein-dependent transport protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: B446_03040
symbol: AGS67440.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: B446_03070
symbol: AGS67446.1
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: B446_03085
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: B446_03090
symbol: AGS67450.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: B446_03100
symbol: AGS67452.1
gene_biotype: protein_coding
description:
  Polyamine ABC-transporter integral membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: B446_03115
symbol: AGS67455.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.


ensembl_gene_id: B446_03140
symbol: AGS67460.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: B446_03190
symbol: AGS67470.1
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: B446_03200
symbol: AGS67472.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporters inner membrane component; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: B446_03205
symbol: AGS67473.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporters inner membrane component; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: B446_03210
symbol: potA-2
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: B446_03235
symbol: AGS67479.1
gene_biotype: protein_coding
description:
  Magnesium or manganese-dependent protein phosphatase; COG2208 Serine phosphatase RsbU, regulator of sigma subunit.


ensembl_gene_id: B446_03240
symbol: AGS67480.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: B446_03280
symbol: AGS67488.1
gene_biotype: protein_coding
description:
  Putative channel transporter; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: B446_03310
symbol: AGS67494.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: B446_03320
symbol: AGS67496.1
gene_biotype: protein_coding
description:
  Carbonyl reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_03325
symbol: AGS67497.1
gene_biotype: protein_coding
description:
  Cytosine/purines uracil thiamine allantoin permease; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: B446_03340
symbol: nadK
gene_biotype: protein_coding
description:
  ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: B446_03370
symbol: AGS67506.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_03395
symbol: AGS67511.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: B446_03440
symbol: AGS67520.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: B446_03510
symbol: AGS67534.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_03520
symbol: AGS67536.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: B446_03525
symbol: AGS67537.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: B446_03565
symbol: AGS67545.1
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: B446_03645
symbol: hypA
gene_biotype: protein_coding
description:
  [NiFe] hydrogenase expression/formation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: B446_03670
symbol: AGS67566.1
gene_biotype: protein_coding
description:
  [NiFe] hydrogenase expression/formation protein; COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase.


ensembl_gene_id: B446_03745
symbol: AGS67581.1
gene_biotype: protein_coding
description:
  Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.


ensembl_gene_id: B446_03770
symbol: AGS67586.1
gene_biotype: protein_coding
description:
  CsbD family protein; COG3237 Uncharacterized protein conserved in bacteria; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: B446_03810
symbol: AGS67594.1
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase Fe4S4 region; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: B446_03815
symbol: AGS67595.1
gene_biotype: protein_coding
description:
  Formate dehydrogenase subunit alpha; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: B446_03830
symbol: selA
gene_biotype: protein_coding
description:
  Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: B446_03860
symbol: AGS67604.1
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: B446_03885
symbol: AGS67609.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.


ensembl_gene_id: B446_03910
symbol: AGS67612.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: B446_03930
symbol: AGS67616.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_04020
symbol: AGS67632.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_04040
symbol: AGS67636.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: B446_04070
symbol: AGS67642.1
gene_biotype: protein_coding
description:
  Regulatory protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: B446_04085
symbol: hemC-2
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: B446_04110
symbol: AGS67650.1
gene_biotype: protein_coding
description:
  COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: B446_04125
symbol: AGS67653.1
gene_biotype: protein_coding
description:
  Glycogen debranching protein; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: B446_04140
symbol: glgE
gene_biotype: protein_coding
description:
  Alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: B446_04155
symbol: glgB
gene_biotype: protein_coding
description:
  Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: B446_04160
symbol: AGS67660.1
gene_biotype: protein_coding
description:
  Carboxylate-amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: B446_04210
symbol: AGS67670.1
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: B446_04225
symbol: AGS67673.1
gene_biotype: protein_coding
description:
  Chromosome replication initiation inhibitor protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: B446_04250
symbol: whiB
gene_biotype: protein_coding
description:
  Regulatory protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: B446_04360
symbol: AGS67700.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_04395
symbol: AGS67707.1
gene_biotype: protein_coding
description:
  Hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: B446_04510
symbol: add
gene_biotype: protein_coding
description:
  COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: B446_04515
symbol: AGS67731.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance family protein; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: B446_04535
symbol: AGS67735.1
gene_biotype: protein_coding
description:
  COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: B446_04595
symbol: AGS67747.1
gene_biotype: protein_coding
description:
  Beta-mannosidase; COG3250 Beta-galactosidase/beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family.


ensembl_gene_id: B446_04620
symbol: AGS67752.1
gene_biotype: protein_coding
description:
  Protease (secreted protein); COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_04635
symbol: AGS67755.1
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactone hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_04640
symbol: AGS67756.1
gene_biotype: protein_coding
description:
  Esterase/lipase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_04645
symbol: AGS67757.1
gene_biotype: protein_coding
description:
  Modular polyketide synthase; COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes.


ensembl_gene_id: B446_04665
symbol: iolG
gene_biotype: protein_coding
description:
  Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).


ensembl_gene_id: B446_04730
symbol: AGS67774.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.


ensembl_gene_id: B446_04740
symbol: AGS67776.1
gene_biotype: protein_coding
description:
  phenylacetate:CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: B446_04810
symbol: AGS67790.1
gene_biotype: protein_coding
description:
  Thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: B446_04860
symbol: AGS67800.1
gene_biotype: protein_coding
description:
  Bifunctional synthase/transferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: B446_05055
symbol: AGS67839.1
gene_biotype: protein_coding
description:
  Myo-inositol 1-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: B446_05105
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: B446_05150
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: B446_05155
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: B446_05190
symbol: pqqB
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqB; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: B446_05260
symbol: AGS67878.1
gene_biotype: protein_coding
description:
  Bifunctional: xanthine dehydrogenase/ 4-hydroxybenzoyl-CoA reductase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: B446_05265
symbol: AGS67879.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: B446_05300
symbol: AGS67886.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_05315
symbol: AGS67889.1
gene_biotype: protein_coding
description:
  Transmembrane transport protein; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: B446_05340
symbol: AGS67894.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_05345
symbol: AGS67895.1
gene_biotype: protein_coding
description:
  MutT/NUDIX-family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: B446_05350
symbol: lnt
gene_biotype: protein_coding
description:
  Transferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: B446_05370
symbol: AGS67900.1
gene_biotype: protein_coding
description:
  Tellurium resistance protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: B446_05440
symbol: rlmG
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: B446_05485
symbol: AGS67923.1
gene_biotype: protein_coding
description:
  Two component system response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: B446_05520
symbol: AGS67930.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: B446_05570
symbol: AGS67940.1
gene_biotype: protein_coding
description:
  Flavin-dependent reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: B446_05650
symbol: AGS67956.1
gene_biotype: protein_coding
description:
  NADPH-ferredoxin reductase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: B446_05680
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: B446_05810
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: B446_05815
symbol: AGS67989.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: B446_05835
symbol: AGS67993.1
gene_biotype: protein_coding
description:
  ABC transporter transmembrane subunit; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: B446_05915
symbol: AGS68009.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_05970
symbol: AGS68018.1
gene_biotype: protein_coding
description:
  Xylose repressor, ROK-family transcriptional regulator; COG1940 Transcriptional regulator/sugar kinase.


ensembl_gene_id: B446_06125
symbol: AGS68049.1
gene_biotype: protein_coding
description:
  NRPS protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: B446_06145
symbol: pqqE
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: B446_06155
symbol: pqqC
gene_biotype: protein_coding
description:
  Pyrroloquinoline quinone biosynthesis protein PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: B446_06240
symbol: AGS68072.1
gene_biotype: protein_coding
description:
  Putative peptidase M38 family protein; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.


ensembl_gene_id: B446_06250
symbol: AGS68074.1
gene_biotype: protein_coding
description:
  Putative transporter; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: B446_06255
symbol: AGS68075.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: B446_06265
symbol: AGS68077.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.


ensembl_gene_id: B446_06290
symbol: ligB
gene_biotype: protein_coding
description:
  ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.


ensembl_gene_id: B446_06335
symbol: def-2
gene_biotype: protein_coding
description:
  Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: B446_06350
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: B446_06375
symbol: AGS68099.1
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_06410
symbol: AGS68106.1
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: B446_06420
symbol: AGS68108.1
gene_biotype: protein_coding
description:
  1-acylglycerol-3-phosphate O-acyltransferase; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.


ensembl_gene_id: B446_06425
symbol: AGS68109.1
gene_biotype: protein_coding
description:
  Reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_06430
symbol: AGS68110.1
gene_biotype: protein_coding
description:
  Secreted tripeptidylaminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_06435
symbol: ureH
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: B446_06440
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: B446_06455
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: B446_06460
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: B446_06475
symbol: clpP-2
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: B446_06485
symbol: AGS68121.1
gene_biotype: protein_coding
description:
  NLP/P60 family protein (secreted protein); COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: B446_06510
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: B446_06515
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: B446_06520
symbol: bioD
gene_biotype: protein_coding
description:
  Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: B446_06545
symbol: AGS68133.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: B446_06715
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: B446_06750
symbol: AGS68174.1
gene_biotype: protein_coding
description:
  Cation efflux system protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: B446_06775
symbol: AGS68179.1
gene_biotype: protein_coding
description:
  Siderophore binding protein; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.


ensembl_gene_id: B446_06795
symbol: AGS68183.1
gene_biotype: protein_coding
description:
  MGT family glycosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: B446_06810
symbol: AGS68186.1
gene_biotype: protein_coding
description:
  COG3321 Polyketide synthase modules and related proteins; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: B446_06850
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: B446_06875
symbol: AGS68199.1
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: B446_06905
symbol: lnt-2
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: B446_06930
symbol: AGS68210.1
gene_biotype: protein_coding
description:
  Solute binding transport lipoprotein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: B446_06935
symbol: AGS68211.1
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_06940
symbol: AGS68212.1
gene_biotype: protein_coding
description:
  3-oxoacyl-acyl-carrier protein reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_06955
symbol: AGS68215.1
gene_biotype: protein_coding
description:
  Iron sulfur protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: B446_07045
symbol: AGS68233.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_07070
symbol: AGS68238.1
gene_biotype: protein_coding
description:
  FeS- and molybdenum cofactor-binding subunit of putative xanthine dehydrogenase/xanthine oxidase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: B446_07085
symbol: AGS68241.1
gene_biotype: protein_coding
description:
  ABC transporter membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: B446_07090
symbol: AGS68242.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_07100
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: B446_07110
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: B446_07150
symbol: AGS68254.1
gene_biotype: protein_coding
description:
  Mannose-1-phosphate guanyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: B446_07155
symbol: AGS68255.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: B446_07165
symbol: AGS68257.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: B446_07180
symbol: AGS68260.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: B446_07200
symbol: AGS68264.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: B446_07205
symbol: AGS68265.1
gene_biotype: protein_coding
description:
  COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: B446_07210
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: B446_07275
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: B446_07345
symbol: rbpA
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: B446_07375
symbol: AGS68299.1
gene_biotype: protein_coding
description:
  Aminoglycoside phosphotransferase-like protein; COG3173 Predicted aminoglycoside phosphotransferase.


ensembl_gene_id: B446_07450
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: B446_07460
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: B446_07465
symbol: ribBA
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: B446_07510
symbol: AGS68326.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_07605
symbol: AGS68345.1
gene_biotype: protein_coding
description:
  RNA-binding Sun protein; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: B446_07610
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: B446_07620
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: B446_07625
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: B446_07630
symbol: AGS68350.1
gene_biotype: protein_coding
description:
  Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: B446_07635
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: B446_07650
symbol: pyrF
gene_biotype: protein_coding
description:
  COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: B446_07655
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: B446_07675
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: B446_07680
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: B446_07685
symbol: pyrR
gene_biotype: protein_coding
description:
  Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: B446_07695
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: B446_07700
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: B446_07715
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: B446_07720
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: B446_07725
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: B446_07735
symbol: mltG-2
gene_biotype: protein_coding
description:
  Integral membrane protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: B446_07740
symbol: AGS68372.1
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: B446_07745
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: B446_07765
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: B446_07770
symbol: AGS68378.1
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: B446_07800
symbol: AGS68384.1
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: B446_07810
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: B446_07815
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: B446_07820
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: B446_07830
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: B446_07835
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: B446_07840
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: B446_07850
symbol: pdxT
gene_biotype: protein_coding
description:
  Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: B446_07855
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: B446_07875
symbol: AGS68399.1
gene_biotype: protein_coding
description:
  COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: B446_07890
symbol: AGS68402.1
gene_biotype: protein_coding
description:
  HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: B446_07895
symbol: AGS68403.1
gene_biotype: protein_coding
description:
  Ion transport 2 domain protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: B446_07960
symbol: AGS68416.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: B446_07995
symbol: AGS68423.1
gene_biotype: protein_coding
description:
  uroporphyrin-III methyltransferase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: B446_08000
symbol: cobT-2
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: B446_08015
symbol: AGS68427.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: B446_08025
symbol: metN
gene_biotype: protein_coding
description:
  Methionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: B446_08140
symbol: AGS68452.1
gene_biotype: protein_coding
description:
  Thiamine biosynthesis lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: B446_08145
symbol: AGS68453.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: B446_08170
symbol: argD
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: B446_08175
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: B446_08180
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: B446_08185
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: B446_08265
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: B446_08270
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: B446_08280
symbol: AGS68480.1
gene_biotype: protein_coding
description:
  COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: B446_08285
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: B446_08425
symbol: tatC
gene_biotype: protein_coding
description:
  Integral membrane protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: B446_08430
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: B446_08465
symbol: pafA
gene_biotype: protein_coding
description:
  Proteasome component; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.


ensembl_gene_id: B446_08490
symbol: prcA
gene_biotype: protein_coding
description:
  20S proteasome subunits A and B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.


ensembl_gene_id: B446_08495
symbol: prcB
gene_biotype: protein_coding
description:
  20S proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.


ensembl_gene_id: B446_08500
symbol: pup
gene_biotype: protein_coding
description:
  Ubiquitin-like protein pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family.


ensembl_gene_id: B446_08510
symbol: arc
gene_biotype: protein_coding
description:
  AAA ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.


ensembl_gene_id: B446_08525
symbol: AGS68529.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.


ensembl_gene_id: B446_08545
symbol: AGS68533.1
gene_biotype: protein_coding
description:
  Lipoprotein oligopeptide binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: B446_08555
symbol: AGS68535.1
gene_biotype: protein_coding
description:
  5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: B446_08590
symbol: mshC
gene_biotype: protein_coding
description:
  cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.


ensembl_gene_id: B446_08610
symbol: corA
gene_biotype: protein_coding
description:
  Ion transport protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: B446_08620
symbol: AGS68548.1
gene_biotype: protein_coding
description:
  ATP/GTP-binding protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_08630
symbol: AGS68550.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: B446_08730
symbol: AGS68570.1
gene_biotype: protein_coding
description:
  COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_08735
symbol: AGS68571.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: B446_08800
symbol: AGS68584.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB.


ensembl_gene_id: B446_08865
symbol: AGS68597.1
gene_biotype: protein_coding
description:
  ABC sugar transporter, ATP-binding subunit; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_08880
symbol: AGS68600.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: B446_08895
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: B446_08910
symbol: AGS68606.1
gene_biotype: protein_coding
description:
  COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: B446_09050
symbol: AGS68634.1
gene_biotype: protein_coding
description:
  COG0587 DNA polymerase III, alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.


ensembl_gene_id: B446_09065
symbol: sepF
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: B446_09115
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: B446_09150
symbol: AGS68654.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: B446_09155
symbol: AGS68655.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: B446_09160
symbol: AGS68656.1
gene_biotype: protein_coding
description:
  ScpA-like chromosome partitioning protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: B446_09185
symbol: AGS68661.1
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: B446_09190
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: B446_09225
symbol: ppnK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: B446_09245
symbol: AGS68673.1
gene_biotype: protein_coding
description:
  Iron-siderophore uptake system ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: B446_09250
symbol: AGS68674.1
gene_biotype: protein_coding
description:
  Iron-siderophore uptake system permease protein; COG4779 ABC-type enterobactin transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: B446_09255
symbol: AGS68675.1
gene_biotype: protein_coding
description:
  COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: B446_09310
symbol: AGS68685.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA.


ensembl_gene_id: B446_09340
symbol: AGS68691.1
gene_biotype: protein_coding
description:
  S-adenosylmethionine: tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: B446_09400
symbol: AGS68703.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_09425
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: B446_09445
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: B446_09465
symbol: AGS68716.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: B446_09490
symbol: AGS68721.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_09600
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: B446_09605
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: B446_09610
symbol: cobN
gene_biotype: protein_coding
description:
  Cobaltochelatase subunit CobN; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: B446_09620
symbol: AGS68747.1
gene_biotype: protein_coding
description:
  cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; COG2109 ATP:corrinoid adenosyltransferase.


ensembl_gene_id: B446_09625
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: B446_09665
symbol: AGS68756.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: B446_09680
symbol: AGS68759.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: B446_09690
symbol: AGS68761.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: B446_09700
symbol: ectA
gene_biotype: protein_coding
description:
  L-2,4-diaminobutyrate acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.


ensembl_gene_id: B446_09705
symbol: AGS68764.1
gene_biotype: protein_coding
description:
  Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_09710
symbol: ectC
gene_biotype: protein_coding
description:
  L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.


ensembl_gene_id: B446_09810
symbol: AGS68785.1
gene_biotype: protein_coding
description:
  5-dehydro-4-deoxyglucarate dehydratase; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: B446_09825
symbol: AGS68788.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_09835
symbol: AGS68790.1
gene_biotype: protein_coding
description:
  Integral membrane sugar transport protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: B446_09845
symbol: AGS68792.1
gene_biotype: protein_coding
description:
  Transport associated protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: B446_09905
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: B446_09945
symbol: dapD
gene_biotype: protein_coding
description:
  Transferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: B446_09975
symbol: AGS68818.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_09980
symbol: AGS68819.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.


ensembl_gene_id: B446_09990
symbol: AGS68821.1
gene_biotype: protein_coding
description:
  Iron-regulated ABC-type transporter; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: B446_10040
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: B446_10045
symbol: AGS68832.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: B446_10050
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.


ensembl_gene_id: B446_10055
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: B446_10080
symbol: AGS68839.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_10115
symbol: rbpA-2
gene_biotype: protein_coding
description:
  Electron transport protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: B446_10120
symbol: AGS68847.1
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: B446_10125
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: B446_10145
symbol: whiA
gene_biotype: protein_coding
description:
  Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.


ensembl_gene_id: B446_10150
symbol: AGS68853.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: B446_10160
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: B446_10185
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: B446_10215
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: B446_10235
symbol: AGS68870.1
gene_biotype: protein_coding
description:
  Export associated protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: B446_10245
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: B446_10260
symbol: AGS68875.1
gene_biotype: protein_coding
description:
  methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: B446_10270
symbol: psuG
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: B446_10285
symbol: corA-2
gene_biotype: protein_coding
description:
  Metal-transport protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: B446_10365
symbol: AGS68896.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).


ensembl_gene_id: B446_10385
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: B446_10445
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: B446_10450
symbol: AGS68912.1
gene_biotype: protein_coding
description:
  COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: B446_10470
symbol: AGS68916.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: B446_10475
symbol: AGS68917.1
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: B446_10480
symbol: AGS68918.1
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: B446_10510
symbol: AGS68924.1
gene_biotype: protein_coding
description:
  2',3'-cyclic-nucleotide 2'-phosphodiesterase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: B446_10650
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: B446_10665
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: B446_10675
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: B446_10710
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: B446_10715
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: B446_10740
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: B446_10750
symbol: priA-2
gene_biotype: protein_coding
description:
  Phosphoribosyl isomerase A; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.


ensembl_gene_id: B446_10755
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: B446_10770
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: B446_10775
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: B446_10805
symbol: AGS68983.1
gene_biotype: protein_coding
description:
  ABC transporter integral membrane transport protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: B446_10860
symbol: AGS68994.1
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: B446_10870
symbol: AGS68996.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: B446_10875
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: B446_10890
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.


ensembl_gene_id: B446_10905
symbol: sepF-2
gene_biotype: protein_coding
description:
  Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: B446_10910
symbol: AGS69004.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: B446_10920
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: B446_10925
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: B446_10930
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: B446_10940
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: B446_10945
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: B446_10950
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate- D-alanyl-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: B446_10955
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: B446_10970
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: B446_10985
symbol: AGS69019.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: B446_11040
symbol: AGS69030.1
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: B446_11045
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: B446_11075
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: B446_11085
symbol: nfo
gene_biotype: protein_coding
description:
  Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: B446_11095
symbol: AGS69041.1
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: B446_11105
symbol: AGS69043.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: B446_11115
symbol: pfp
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: B446_11240
symbol: trpD1
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: B446_11275
symbol: AGS69077.1
gene_biotype: protein_coding
description:
  Integral membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.


ensembl_gene_id: B446_11290
symbol: AGS69080.1
gene_biotype: protein_coding
description:
  Pyridoxalphosphate dependent protein; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: B446_11315
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: B446_11325
symbol: AGS69087.1
gene_biotype: protein_coding
description:
  Integral membrane efflux protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: B446_11375
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: B446_11395
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: B446_11420
symbol: pepA
gene_biotype: protein_coding
description:
  Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: B446_11425
symbol: AGS69107.1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: B446_11430
symbol: AGS69108.1
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: B446_11440
symbol: AGS69110.1
gene_biotype: protein_coding
description:
  2-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: B446_11475
symbol: AGS69117.1
gene_biotype: protein_coding
description:
  NAD dependent epimerase/dehydratase family protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase.


ensembl_gene_id: B446_11490
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: B446_11495
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: B446_11525
symbol: AGS69127.1
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: B446_11555
symbol: htpX
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: B446_11585
symbol: AGS69139.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: B446_11605
symbol: AGS69143.1
gene_biotype: protein_coding
description:
  Regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_11715
symbol: glnE
gene_biotype: protein_coding
description:
  Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]


ensembl_gene_id: B446_11810
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: B446_11855
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: B446_11865
symbol: AGS69195.1
gene_biotype: protein_coding
description:
  ABC-transporter, transmembrane component; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: B446_11870
symbol: AGS69196.1
gene_biotype: protein_coding
description:
  Multi-domain regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_11915
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: B446_11935
symbol: AGS69209.1
gene_biotype: protein_coding
description:
  Iron-dependent peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: B446_12035
symbol: AGS69229.1
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: B446_12065
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_12110
symbol: AGS69244.1
gene_biotype: protein_coding
description:
  Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: B446_12135
symbol: AGS69249.1
gene_biotype: protein_coding
description:
  FMN-dependent monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_12230
symbol: AGS69268.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: B446_12365
symbol: AGS69295.1
gene_biotype: protein_coding
description:
  COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: B446_12400
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: B446_12405
symbol: AGS69303.1
gene_biotype: protein_coding
description:
  Ion transport integral membrane protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: B446_12465
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: B446_12470
symbol: acpP
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: B446_12475
symbol: AGS69317.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: B446_12540
symbol: AGS69330.1
gene_biotype: protein_coding
description:
  Dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: B446_12555
symbol: AGS69333.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter sugar-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: B446_12570
symbol: AGS69334.1
gene_biotype: protein_coding
description:
  Sugar transport permease; COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: B446_12580
symbol: AGS69336.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: B446_12630
symbol: AGS69346.1
gene_biotype: protein_coding
description:
  Short-chain oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_12710
symbol: AGS69362.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: B446_12715
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: B446_12725
symbol: AGS69365.1
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: B446_12740
symbol: AGS69368.1
gene_biotype: protein_coding
description:
  Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: B446_12770
symbol: AGS69374.1
gene_biotype: protein_coding
description:
  COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: B446_12800
symbol: AGS69380.1
gene_biotype: protein_coding
description:
  Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: B446_12830
symbol: AGS69384.1
gene_biotype: protein_coding
description:
  Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: B446_12875
symbol: glyQS
gene_biotype: protein_coding
description:
  glycyl-tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: B446_12880
symbol: AGS69394.1
gene_biotype: protein_coding
description:
  COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: B446_12900
symbol: AGS69398.1
gene_biotype: protein_coding
description:
  UDP phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: B446_12915
symbol: AGS69401.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: B446_12920
symbol: AGS69402.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: B446_12925
symbol: AGS69403.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: B446_12930
symbol: AGS69404.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_12935
symbol: AGS69405.1
gene_biotype: protein_coding
description:
  Lysine biosynthesis protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.


ensembl_gene_id: B446_13040
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: B446_13065
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: B446_13125
symbol: ybeY
gene_biotype: protein_coding
description:
  Metal-binding heat shock protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: B446_13140
symbol: AGS69446.1
gene_biotype: protein_coding
description:
  Glucarate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: B446_13155
symbol: AGS69449.1
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: B446_13160
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: B446_13165
symbol: AGS69451.1
gene_biotype: protein_coding
description:
  Hit-family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: B446_13190
symbol: AGS69456.1
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: B446_13200
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: B446_13205
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: B446_13225
symbol: AGS69463.1
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: B446_13240
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: B446_13265
symbol: AGS69471.1
gene_biotype: protein_coding
description:
  Putative 4'-phosphopantetheinyl transferase; COG2091 Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: B446_13275
symbol: AGS69473.1
gene_biotype: protein_coding
description:
  Putative type I polyketide synthase component; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: B446_13305
symbol: AGS69479.1
gene_biotype: protein_coding
description:
  SARP family pathway specific regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_13320
symbol: AGS69482.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: B446_13345
symbol: AGS69487.1
gene_biotype: protein_coding
description:
  Actinorhodin polyketide synthase bifunctional cyclase/dehydratase; COG2867 Oligoketide cyclase/lipid transport protein.


ensembl_gene_id: B446_13355
symbol: AGS69489.1
gene_biotype: protein_coding
description:
  acyl-CoA ligase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: B446_13370
symbol: AGS69492.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: B446_13375
symbol: AGS69493.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: B446_13385
symbol: AGS69495.1
gene_biotype: protein_coding
description:
  Putative secondary metabolite biosynthesis protein; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III.


ensembl_gene_id: B446_13390
symbol: AGS69496.1
gene_biotype: protein_coding
description:
  Putative cytoplasmic protein; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.


ensembl_gene_id: B446_13430
symbol: AGS69504.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, EmrB/QacA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: B446_13450
symbol: AGS69508.1
gene_biotype: protein_coding
description:
  Non-ribosomal peptide synthase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_13465
symbol: AGS69511.1
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: B446_13470
symbol: AGS69512.1
gene_biotype: protein_coding
description:
  Oxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: B446_13485
symbol: AGS69515.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein RfbH; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: B446_13510
symbol: AGS69520.1
gene_biotype: protein_coding
description:
  N-hydroxyarylamine O-acetyltransferase; COG2162 Arylamine N-acetyltransferase; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: B446_13565
symbol: AGS69531.1
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: B446_13570
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: B446_13580
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: B446_13610
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: B446_13620
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: B446_13640
symbol: ispD-2
gene_biotype: protein_coding
description:
  Bifunctional ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_13645
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: B446_13655
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: B446_13785
symbol: AGS69575.1
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family.


ensembl_gene_id: B446_13840
symbol: ndk
gene_biotype: protein_coding
description:
  Multifunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: B446_13855
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: B446_13865
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: B446_13870
symbol: clpP-3
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: B446_13880
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: B446_13910
symbol: AGS69600.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.


ensembl_gene_id: B446_13915
symbol: AGS69601.1
gene_biotype: protein_coding
description:
  Endonuclease VIII and DNA N-glycosylase with an AP lyase activity; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.


ensembl_gene_id: B446_13955
symbol: AGS69609.1
gene_biotype: protein_coding
description:
  Transport-associated lipoprotein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: B446_13965
symbol: ssuB
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: B446_13985
symbol: AGS69615.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: B446_14020
symbol: AGS69622.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: B446_14050
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: B446_14145
symbol: AGS69647.1
gene_biotype: protein_coding
description:
  Sugar hydrolase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: B446_14155
symbol: AGS69649.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase.


ensembl_gene_id: B446_14165
symbol: AGS69651.1
gene_biotype: protein_coding
description:
  Sugar-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: B446_14265
symbol: AGS69671.1
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: B446_14285
symbol: AGS69675.1
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: B446_14315
symbol: AGS69681.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_14415
symbol: AGS69701.1
gene_biotype: protein_coding
description:
  Lipoprotein; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.


ensembl_gene_id: B446_14510
symbol: recD2
gene_biotype: protein_coding
description:
  Deoxyribonuclease; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: B446_14520
symbol: rbsA
gene_biotype: protein_coding
description:
  ABC transporter protein, ATP binding component; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: B446_14525
symbol: AGS69723.1
gene_biotype: protein_coding
description:
  D-ribose ABC transporter permease protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: B446_14530
symbol: rbsK-2
gene_biotype: protein_coding
description:
  Carbohydrate kinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: B446_14570
symbol: AGS69732.1
gene_biotype: protein_coding
description:
  beta-N-acetylhexosaminidase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: B446_14600
symbol: AGS69738.1
gene_biotype: protein_coding
description:
  Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: B446_14605
symbol: AGS69739.1
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: B446_14665
symbol: AGS69751.1
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter substrate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: B446_14715
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: B446_14735
symbol: AGS69765.1
gene_biotype: protein_coding
description:
  Transcriptional activator AdpA; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: B446_14740
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: B446_14755
symbol: AGS69769.1
gene_biotype: protein_coding
description:
  Cellobiose ABC transporter permease protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: B446_14795
symbol: AGS69777.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: B446_14845
symbol: AGS69787.1
gene_biotype: protein_coding
description:
  Sensory box/GGDEF family protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: B446_14850
symbol: AGS69788.1
gene_biotype: protein_coding
description:
  LuxAB-like protein (oxygenase); COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_14870
symbol: AGS69792.1
gene_biotype: protein_coding
description:
  Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: B446_14945
symbol: AGS69807.1
gene_biotype: protein_coding
description:
  N-acetylglucosamine-6-phosphate deacetylase; COG0647 Predicted sugar phosphatases of the HAD superfamily; Belongs to the HAD-like hydrolase superfamily.


ensembl_gene_id: B446_14950
symbol: AGS69808.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.


ensembl_gene_id: B446_15005
symbol: AGS69819.1
gene_biotype: protein_coding
description:
  2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: B446_15105
symbol: AGS69839.1
gene_biotype: protein_coding
description:
  dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: B446_15150
symbol: AGS69848.1
gene_biotype: protein_coding
description:
  Integral membrane transport protein; COG3694 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: B446_15155
symbol: AGS69849.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4586 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: B446_15170
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: B446_15180
symbol: AGS69854.1
gene_biotype: protein_coding
description:
  PTS transmembrane protein; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.


ensembl_gene_id: B446_15225
symbol: AGS69863.1
gene_biotype: protein_coding
description:
  Mov34/MPN/PAD-1 family protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.


ensembl_gene_id: B446_15240
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: B446_15245
symbol: AGS69867.1
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: B446_15350
symbol: AGS69888.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: B446_15355
symbol: AGS69889.1
gene_biotype: protein_coding
description:
  Iron-suplhur oxidoreductase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: B446_15375
symbol: AGS69893.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: B446_15380
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: B446_15385
symbol: AGS69895.1
gene_biotype: protein_coding
description:
  DNA-binding protein HU 1; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: B446_15420
symbol: AGS69902.1
gene_biotype: protein_coding
description:
  Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase.


ensembl_gene_id: B446_15440
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: B446_15450
symbol: AGS69908.1
gene_biotype: protein_coding
description:
  Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: B446_15470
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: B446_15520
symbol: AGS69922.1
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: B446_15560
symbol: AGS69930.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component.


ensembl_gene_id: B446_15565
symbol: AGS69931.1
gene_biotype: protein_coding
description:
  CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC.


ensembl_gene_id: B446_15610
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: B446_15630
symbol: hpf
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: B446_15655
symbol: AGS69949.1
gene_biotype: protein_coding
description:
  COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: B446_15680
symbol: AGS69954.1
gene_biotype: protein_coding
description:
  Lipoprotein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: B446_15700
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: B446_15750
symbol: whiB-2
gene_biotype: protein_coding
description:
  Sporulation regulatory protein WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: B446_15765
symbol: fbiA
gene_biotype: protein_coding
description:
  LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.


ensembl_gene_id: B446_15770
symbol: fbiB
gene_biotype: protein_coding
description:
  F420-0--gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.


ensembl_gene_id: B446_15780
symbol: AGS69974.1
gene_biotype: protein_coding
description:
  Nucleotide phosphorylase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: B446_15870
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: B446_15875
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: B446_15930
symbol: AGS70004.1
gene_biotype: protein_coding
description:
  COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Belongs to the sigma-70 factor family.


ensembl_gene_id: B446_15945
symbol: AGS70007.1
gene_biotype: protein_coding
description:
  N-formimino-L-glutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: B446_15950
symbol: AGS70008.1
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: B446_16070
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: B446_16115
symbol: AGS70041.1
gene_biotype: protein_coding
description:
  Type II restriction-modification system DNA adenine-specific methylase; COG0286 Type I restriction-modification system methyltransferase subunit.


ensembl_gene_id: B446_16135
symbol: mfd
gene_biotype: protein_coding
description:
  Transcriptional-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: B446_16200
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: B446_16205
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: B446_16210
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: B446_16225
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: B446_16245
symbol: tam
gene_biotype: protein_coding
description:
  Trans-aconitate 2-methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.


ensembl_gene_id: B446_16270
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: B446_16320
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: B446_16325
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: B446_16345
symbol: rsmI
gene_biotype: protein_coding
description:
  Tetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: B446_16370
symbol: AGS70092.1
gene_biotype: protein_coding
description:
  Integral membrane transport protein; COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters.


ensembl_gene_id: B446_16375
symbol: AGS70093.1
gene_biotype: protein_coding
description:
  ABC transport protein ATP-binding subunit; COG1122 ABC-type cobalt transport system, ATPase component.


ensembl_gene_id: B446_16400
symbol: AGS70098.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: B446_16425
symbol: AGS70103.1
gene_biotype: protein_coding
description:
  Protease; COG4946 Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system.


ensembl_gene_id: B446_16435
symbol: AGS70105.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_16480
symbol: AGS70112.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: B446_16490
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: B446_16495
symbol: AGS70115.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: B446_16505
symbol: AGS70117.1
gene_biotype: protein_coding
description:
  Ligase; COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: B446_16540
symbol: mscL
gene_biotype: protein_coding
description:
  Mechanosensitive ion channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: B446_16575
symbol: AGS70131.1
gene_biotype: protein_coding
description:
  Fructose-specific permease; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: B446_16580
symbol: AGS70132.1
gene_biotype: protein_coding
description:
  1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: B446_16605
symbol: AGS70137.1
gene_biotype: protein_coding
description:
  RNA polymerase principal sigma factor hrdD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: B446_16685
symbol: AGS70153.1
gene_biotype: protein_coding
description:
  MutT-like protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: B446_16830
symbol: AGS70182.1
gene_biotype: protein_coding
description:
  Sodium-coupled permease; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: B446_17105
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: B446_17155
symbol: AGS70247.1
gene_biotype: protein_coding
description:
  COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; Belongs to the UPF0309 family.


ensembl_gene_id: B446_17170
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: B446_17180
symbol: AGS70252.1
gene_biotype: protein_coding
description:
  Iron/ascorbate-dependent oxidoreductase; COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: B446_17235
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: B446_17255
symbol: AGS70267.1
gene_biotype: protein_coding
description:
  NDP-4-keto-6-deoxy-L-hexose 2,3-reductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: B446_17260
symbol: AGS70268.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: B446_17345
symbol: mqnB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: B446_17350
symbol: mqnD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.


ensembl_gene_id: B446_17435
symbol: murQ
gene_biotype: protein_coding
description:
  N-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.


ensembl_gene_id: B446_17480
symbol: groEL2
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: B446_17500
symbol: AGS70316.1
gene_biotype: protein_coding
description:
  Glucosyl-3-phosphoglycerate synthase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: B446_17535
symbol: AGS70323.1
gene_biotype: protein_coding
description:
  Sugar kinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: B446_17550
symbol: AGS70326.1
gene_biotype: protein_coding
description:
  Reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: B446_17560
symbol: AGS70328.1
gene_biotype: protein_coding
description:
  Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: B446_17635
symbol: AGS70343.1
gene_biotype: protein_coding
description:
  PKSA beta-ketoacylsynthase subunit beta; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: B446_17640
symbol: AGS70344.1
gene_biotype: protein_coding
description:
  Ketosynthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: B446_17650
symbol: AGS70346.1
gene_biotype: protein_coding
description:
  Polyketide-based spore pigment synthesis protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: B446_17655
symbol: AGS70347.1
gene_biotype: protein_coding
description:
  Polyketide hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: B446_17670
symbol: AGS70350.1
gene_biotype: protein_coding
description:
  Guanyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: B446_17695
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: B446_17700
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: B446_17750
symbol: AGS70366.1
gene_biotype: protein_coding
description:
  Integral membrane protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: B446_17800
symbol: AGS70376.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes.


ensembl_gene_id: B446_17845
symbol: mshA
gene_biotype: protein_coding
description:
  Glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.


ensembl_gene_id: B446_17855
symbol: AGS70387.1
gene_biotype: protein_coding
description:
  NLP/P60-family secreted protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: B446_17945
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: B446_17950
symbol: AGS70406.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family.


ensembl_gene_id: B446_18020
symbol: AGS70420.1
gene_biotype: protein_coding
description:
  Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: B446_18040
symbol: AGS70424.1
gene_biotype: protein_coding
description:
  COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: B446_18045
symbol: mshD
gene_biotype: protein_coding
description:
  Acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.


ensembl_gene_id: B446_18070
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: B446_18110
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: B446_18120
symbol: AGS70440.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: B446_18125
symbol: AGS70441.1
gene_biotype: protein_coding
description:
  Phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: B446_18140
symbol: AGS70444.1
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: B446_18215
symbol: AGS70459.1
gene_biotype: protein_coding
description:
  Regulator; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: B446_18240
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: B446_18265
symbol: AGS70469.1
gene_biotype: protein_coding
description:
  Bifunctional deaminase/reductase-like protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis.


ensembl_gene_id: B446_18275
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: B446_18335
symbol: AGS70483.1
gene_biotype: protein_coding
description:
  Valine dehydrogenase (NADP+); COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: B446_18350
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: B446_18370
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: B446_18375
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: B446_18380
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought  [...]


ensembl_gene_id: B446_18410
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: B446_18430
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: B446_18465
symbol: AGS70509.1
gene_biotype: protein_coding
description:
  Transport integral membrane protein; COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC.


ensembl_gene_id: B446_18510
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: B446_18525
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine/deoxycytidine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: B446_18540
symbol: AGS70524.1
gene_biotype: protein_coding
description:
  SigF-like sigma factor; COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: B446_18715
symbol: AGS70557.1
gene_biotype: protein_coding
description:
  Protease (secreted protein); COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: B446_18780
symbol: AGS70570.1
gene_biotype: protein_coding
description:
  COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: B446_18795
symbol: AGS70573.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: B446_18805
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: B446_18820
symbol: AGS70578.1
gene_biotype: protein_coding
description:
  Integral membrane protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: B446_18845
symbol: AGS70583.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_18855
symbol: kptA
gene_biotype: protein_coding
description:
  Phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.


ensembl_gene_id: B446_18870
symbol: AGS70588.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.


ensembl_gene_id: B446_18890
symbol: pat
gene_biotype: protein_coding
description:
  Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_18910
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: B446_18950
symbol: AGS70604.1
gene_biotype: protein_coding
description:
  Low molecular weight protein-tyrosine-phosphatase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: B446_18970
symbol: AGS70608.1
gene_biotype: protein_coding
description:
  Flavohemoprotein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Belongs to the globin family.


ensembl_gene_id: B446_19010
symbol: AGS70616.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: B446_19080
symbol: AGS70630.1
gene_biotype: protein_coding
description:
  COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: B446_19135
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: B446_19150
symbol: AGS70644.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: B446_19155
symbol: rnpA
gene_biotype: protein_coding
description:
  RNase P component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: B446_19165
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: B446_19170
symbol: AGS70648.1
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: B446_19180
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: B446_19185
symbol: AGS70651.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives; Belongs to the UPF0232 family.


ensembl_gene_id: B446_19190
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: B446_19195
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: B446_19270
symbol: AGS70668.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: B446_19405
symbol: AGS70695.1
gene_biotype: protein_coding
description:
  COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: B446_19410
symbol: AGS70696.1
gene_biotype: protein_coding
description:
  COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: B446_19415
symbol: AGS70697.1
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: B446_19420
symbol: AGS70698.1
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: B446_19425
symbol: AGS70699.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: B446_19430
symbol: AGS70700.1
gene_biotype: protein_coding
description:
  Ion channel membrane protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: B446_19565
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: B446_19585
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: B446_19695
symbol: AGS70751.1
gene_biotype: protein_coding
description:
  Transport integral membrane protein; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: B446_19800
symbol: AGS70772.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG3321 Polyketide synthase modules and related proteins.


ensembl_gene_id: B446_19850
symbol: lysY
gene_biotype: protein_coding
description:
  Putative LysW-gamma-L-alpha-aminoadipyl-6-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: B446_19855
symbol: AGS70783.1
gene_biotype: protein_coding
description:
  COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: B446_19860
symbol: AGS70784.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis.


ensembl_gene_id: B446_19865
symbol: AGS70785.1
gene_biotype: protein_coding
description:
  Lysine biosynthesis protein LysX; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the RimK family.


ensembl_gene_id: B446_19875
symbol: AGS70787.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, SARP family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_19885
symbol: dcd
gene_biotype: protein_coding
description:
  Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.


ensembl_gene_id: B446_19900
symbol: AGS70792.1
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: B446_19910
symbol: AGS70794.1
gene_biotype: protein_coding
description:
  Glycosyl transferase family protein; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: B446_19920
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: B446_19935
symbol: AGS70799.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: B446_19945
symbol: AGS70801.1
gene_biotype: protein_coding
description:
  Regulatory protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: B446_19970
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: B446_19990
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: B446_20010
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: B446_20015
symbol: AGS70815.1
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: B446_20040
symbol: AGS70820.1
gene_biotype: protein_coding
description:
  Putative nacht domain-containing signal transduction protein; COG4249 Uncharacterized protein containing caspase domain.


ensembl_gene_id: B446_20055
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: B446_20060
symbol: kynU
gene_biotype: protein_coding
description:
  Hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: B446_20085
symbol: AGS70829.1
gene_biotype: protein_coding
description:
  Two-component system regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: B446_20110
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: B446_20155
symbol: AGS70843.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_20170
symbol: AGS70846.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: B446_20175
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: B446_20390
symbol: AGS70890.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: B446_20395
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: B446_20420
symbol: nhaA
gene_biotype: protein_coding
description:
  pH-dependent sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: B446_20425
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: B446_20430
symbol: AGS70898.1
gene_biotype: protein_coding
description:
  Integral membrane transport protein; COG0659 Sulfate permease and related transporters (MFS superfamily).


ensembl_gene_id: B446_20490
symbol: AGS70910.1
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: B446_20505
symbol: hppA
gene_biotype: protein_coding
description:
  Membrane-bound proton-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: B446_20515
symbol: AGS70915.1
gene_biotype: protein_coding
description:
  rRNA or tRNA methyltransferase; COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily.


ensembl_gene_id: B446_20525
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: B446_20530
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: B446_20555
symbol: AGS70923.1
gene_biotype: protein_coding
description:
  High-affinity nickel-transport protein; COG3376 High-affinity nickel permease; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: B446_20640
symbol: AGS70940.1
gene_biotype: protein_coding
description:
  COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family.


ensembl_gene_id: B446_20670
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: B446_20685
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: B446_20690
symbol: AGS70950.1
gene_biotype: protein_coding
description:
  COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: B446_20695
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein ftsH-like protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: B446_20710
symbol: AGS70954.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: B446_20715
symbol: AGS70955.1
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: B446_20725
symbol: AGS70957.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: B446_20755
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoD2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: B446_20790
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: B446_20805
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: B446_20840
symbol: AGS70980.1
gene_biotype: protein_coding
description:
  Clp family ATP-binding protease; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: B446_20895
symbol: disA
gene_biotype: protein_coding
description:
  DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.


ensembl_gene_id: B446_20900
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: B446_20965
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: B446_20970
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: B446_20990
symbol: AGS71010.1
gene_biotype: protein_coding
description:
  Acetoin utilization protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: B446_21020
symbol: AGS71016.1
gene_biotype: protein_coding
description:
  AdsA-like sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: B446_21035
symbol: rex
gene_biotype: protein_coding
description:
  Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: B446_21040
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: B446_21050
symbol: AGS71022.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase.


ensembl_gene_id: B446_21065
symbol: AGS71025.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: B446_21155
symbol: AGS71043.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_21210
symbol: AGS71054.1
gene_biotype: protein_coding
description:
  Glucose 1-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_21340
symbol: AGS71080.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: B446_21350
symbol: AGS71082.1
gene_biotype: protein_coding
description:
  Decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: B446_21355
symbol: ubiA
gene_biotype: protein_coding
description:
  Prenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: B446_21370
symbol: mqnE
gene_biotype: protein_coding
description:
  Radical SAM protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.


ensembl_gene_id: B446_21435
symbol: mqnA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: B446_21450
symbol: mqnC
gene_biotype: protein_coding
description:
  Hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: B446_21460
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: B446_21480
symbol: def-3
gene_biotype: protein_coding
description:
  Polypetide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: B446_21490
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: B446_21495
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: B446_21500
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: B446_21505
symbol: nuoD-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: B446_21515
symbol: AGS71115.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: B446_21520
symbol: AGS71116.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: B446_21525
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: B446_21530
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: B446_21535
symbol: AGS71119.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: B446_21540
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: B446_21545
symbol: AGS71121.1
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: B446_21555
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: B446_21570
symbol: AGS71126.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: B446_21595
symbol: AGS71131.1
gene_biotype: protein_coding
description:
  Isoprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: B446_21645
symbol: AGS71141.1
gene_biotype: protein_coding
description:
  COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.


ensembl_gene_id: B446_21650
symbol: AGS71142.1
gene_biotype: protein_coding
description:
  COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.


ensembl_gene_id: B446_21670
symbol: AGS71146.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.


ensembl_gene_id: B446_21675
symbol: nuoB-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: B446_21685
symbol: nuoH-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: B446_21690
symbol: nuoI-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: B446_21695
symbol: AGS71151.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: B446_21700
symbol: nuoK-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoK2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: B446_21715
symbol: nuoN-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: B446_21950
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: B446_21955
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: B446_21960
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: B446_21965
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: B446_21975
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: B446_21980
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: B446_21985
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: B446_21995
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: B446_22000
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: B446_22005
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: B446_22050
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: B446_22055
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: B446_22065
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: B446_22070
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: B446_22075
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: B446_22080
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: B446_22085
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: B446_22090
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: B446_22100
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: B446_22105
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: B446_22110
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: B446_22115
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: B446_22120
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: B446_22125
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: B446_22130
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: B446_22135
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: B446_22140
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: B446_22150
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: B446_22155
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: B446_22160
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: B446_22170
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: B446_22180
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: B446_22185
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: B446_22190
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: B446_22200
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: B446_22210
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: B446_22220
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: B446_22235
symbol: AGS71259.1
gene_biotype: protein_coding
description:
  COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family.


ensembl_gene_id: B446_22240
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: B446_22245
symbol: nnrD
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: B446_22250
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: B446_22270
symbol: AGS71266.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: B446_22280
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: B446_22335
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: B446_22350
symbol: AGS71282.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_22365
symbol: whiB-3
gene_biotype: protein_coding
description:
  WhiB-family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: B446_22385
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: B446_22395
symbol: AGS71291.1
gene_biotype: protein_coding
description:
  COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: B446_22400
symbol: AGS71292.1
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: B446_22440
symbol: gabD2
gene_biotype: protein_coding
description:
  Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: B446_22465
symbol: AGS71305.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: B446_22575
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: B446_22580
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: B446_22600
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: B446_22605
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: B446_22615
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: B446_22630
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: B446_22665
symbol: AGS71345.1
gene_biotype: protein_coding
description:
  Glycine betaine ABC transporter integral membrane protein; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: B446_22670
symbol: AGS71346.1
gene_biotype: protein_coding
description:
  Glycine betaine-binding lipoprotein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: B446_22710
symbol: glyA-2
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: B446_22775
symbol: sdhB
gene_biotype: protein_coding
description:
  COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: B446_22830
symbol: AGS71378.1
gene_biotype: protein_coding
description:
  ECF sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: B446_22920
symbol: AGS71396.1
gene_biotype: protein_coding
description:
  Lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: B446_22925
symbol: AGS71397.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter ATP-binding protein; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: B446_22930
symbol: AGS71398.1
gene_biotype: protein_coding
description:
  COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: B446_22935
symbol: AGS71399.1
gene_biotype: protein_coding
description:
  COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: B446_23050
symbol: AGS71422.1
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: B446_23065
symbol: AGS71425.1
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: B446_23075
symbol: AGS71427.1
gene_biotype: protein_coding
description:
  Flavoprotein disulfide reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: B446_23095
symbol: AGS71431.1
gene_biotype: protein_coding
description:
  Septum formation protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: B446_23245
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: B446_23295
symbol: AGS71471.1
gene_biotype: protein_coding
description:
  Dolichol-phosphate mannosyltransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: B446_23320
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: B446_23440
symbol: AGS71500.1
gene_biotype: protein_coding
description:
  Septum site-determining protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: B446_23520
symbol: AGS71516.1
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: B446_23525
symbol: AGS71517.1
gene_biotype: protein_coding
description:
  ATP-binding protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: B446_23540
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.


ensembl_gene_id: B446_23550
symbol: AGS71522.1
gene_biotype: protein_coding
description:
  Hydrogen peroxide sensing regulator; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: B446_23595
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: B446_23610
symbol: AGS71534.1
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: B446_23620
symbol: whiB-4
gene_biotype: protein_coding
description:
  Hypothetical protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: B446_23640
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: B446_23645
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: B446_23655
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: B446_23670
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: B446_23675
symbol: AGS71547.1
gene_biotype: protein_coding
description:
  Addiction module antitoxin; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system.


ensembl_gene_id: B446_23690
symbol: AGS71550.1
gene_biotype: protein_coding
description:
  Putative AfsR-like transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_23705
symbol: AGS71553.1
gene_biotype: protein_coding
description:
  Glutamine amidotransferase of anthranilate synthase; COG0512 Anthranilate/para-aminobenzoate synthases component II.


ensembl_gene_id: B446_23725
symbol: AGS71557.1
gene_biotype: protein_coding
description:
  Flavin reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: B446_23750
symbol: AGS71562.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase I; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: B446_23760
symbol: AGS71564.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_23775
symbol: AGS71567.1
gene_biotype: protein_coding
description:
  Salicylate hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: B446_23915
symbol: AGS71594.1
gene_biotype: protein_coding
description:
  mutT-like protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: B446_23975
symbol: AGS71606.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: B446_23990
symbol: AGS71609.1
gene_biotype: protein_coding
description:
  ABC transporter intracellular ATPase subunit BldKD; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_23995
symbol: AGS71610.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein BldKE; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_24010
symbol: AGS71613.1
gene_biotype: protein_coding
description:
  Gcn5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: B446_24025
symbol: AGS71616.1
gene_biotype: protein_coding
description:
  SARP family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_24035
symbol: AGS71618.1
gene_biotype: protein_coding
description:
  ABC transporter ATPase; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_24050
symbol: AGS71621.1
gene_biotype: protein_coding
description:
  ABC transporter integral membrane protein BldKA; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: B446_24055
symbol: AGS71622.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter substrate-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: B446_24060
symbol: AGS71623.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter substrate-binding protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: B446_24065
symbol: AGS71624.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter integral membrane protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: B446_24070
symbol: AGS71625.1
gene_biotype: protein_coding
description:
  Peptide ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_24075
symbol: AGS71626.1
gene_biotype: protein_coding
description:
  Peptide ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_24090
symbol: mshB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.


ensembl_gene_id: B446_24135
symbol: AGS71638.1
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: B446_24160
symbol: AGS71643.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: B446_24235
symbol: AGS71658.1
gene_biotype: protein_coding
description:
  ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: B446_24360
symbol: AGS71683.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_24385
symbol: AGS71688.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis-like protein MoeZ; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: B446_24420
symbol: AGS71695.1
gene_biotype: protein_coding
description:
  Peptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: B446_24425
symbol: AGS71696.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.


ensembl_gene_id: B446_24440
symbol: whiB-5
gene_biotype: protein_coding
description:
  DNA-binding protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: B446_24520
symbol: AGS71715.1
gene_biotype: protein_coding
description:
  Hydrogen peroxide sensitive repressor; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: B446_24540
symbol: AGS71719.1
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: B446_24555
symbol: rsgA
gene_biotype: protein_coding
description:
  Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: B446_24560
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: B446_24625
symbol: AGS71736.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: B446_24630
symbol: AGS71737.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: B446_24650
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.


ensembl_gene_id: B446_24690
symbol: AGS71749.1
gene_biotype: protein_coding
description:
  Sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: B446_24710
symbol: AGS71753.1
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: B446_24780
symbol: AGS71767.1
gene_biotype: protein_coding
description:
  Arginine/ornithine binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: B446_24845
symbol: kgd
gene_biotype: protein_coding
description:
  Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.


ensembl_gene_id: B446_24870
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: B446_24990
symbol: ku
gene_biotype: protein_coding
description:
  Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: B446_25000
symbol: ku-2
gene_biotype: protein_coding
description:
  Ku70/Ku80 protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: B446_25090
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: B446_25100
symbol: AGS71831.1
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: B446_25105
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: B446_25125
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: B446_25130
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: B446_25150
symbol: AGS71841.1
gene_biotype: protein_coding
description:
  Transferase; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: B446_25165
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: B446_25170
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: B446_25175
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: B446_25180
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: B446_25185
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: B446_25190
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: B446_25195
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: B446_25200
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: B446_25215
symbol: AGS71854.1
gene_biotype: protein_coding
description:
  Winged helix family two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: B446_25245
symbol: AGS71860.1
gene_biotype: protein_coding
description:
  Anti-anti-sigma-factor; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: B446_25255
symbol: nucS
gene_biotype: protein_coding
description:
  Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.


ensembl_gene_id: B446_25265
symbol: AGS71864.1
gene_biotype: protein_coding
description:
  Alkanal monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_25310
symbol: AGS71873.1
gene_biotype: protein_coding
description:
  Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: B446_25315
symbol: AGS71874.1
gene_biotype: protein_coding
description:
  Lysine arginine ornithine transport system kinase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: B446_25420
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: B446_25425
symbol: AGS71895.1
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: B446_25445
symbol: AGS71899.1
gene_biotype: protein_coding
description:
  Two-component sensor kinase; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: B446_25450
symbol: AGS71900.1
gene_biotype: protein_coding
description:
  COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: B446_25640
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: B446_25645
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: B446_25670
symbol: AGS71942.1
gene_biotype: protein_coding
description:
  Family 5 extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: B446_25680
symbol: AGS71944.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_25735
symbol: AGS71955.1
gene_biotype: protein_coding
description:
  Pyridoxal-phosphate-dependent aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: B446_25745
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: B446_25775
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: B446_25780
symbol: AGS71964.1
gene_biotype: protein_coding
description:
  Phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: B446_25790
symbol: gatC
gene_biotype: protein_coding
description:
  asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: B446_25795
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: B446_25805
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: B446_25855
symbol: AGS71979.1
gene_biotype: protein_coding
description:
  Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: B446_25865
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: B446_25910
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.


ensembl_gene_id: B446_25920
symbol: AGS71992.1
gene_biotype: protein_coding
description:
  Transmembrane transport protein; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: B446_25925
symbol: ureAB
gene_biotype: protein_coding
description:
  COG0831 Urea amidohydrolase (urease) gamma subunit; In the C-terminal section; belongs to the urease beta subunit family.


ensembl_gene_id: B446_25945
symbol: AGS71997.1
gene_biotype: protein_coding
description:
  Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: B446_25960
symbol: AGS72000.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: B446_26010
symbol: AGS72010.1
gene_biotype: protein_coding
description:
  Roadblock/LC7 family protein; COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid.


ensembl_gene_id: B446_26050
symbol: AGS72018.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: B446_26055
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: B446_26070
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: B446_26075
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: B446_26085
symbol: AGS72025.1
gene_biotype: protein_coding
description:
  Histone-like DNA binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: B446_26095
symbol: fbiD
gene_biotype: protein_coding
description:
  Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.


ensembl_gene_id: B446_26105
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: B446_26110
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: B446_26125
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: B446_26155
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: B446_26165
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: B446_26185
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: B446_26190
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: B446_26230
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome associated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: B446_26235
symbol: AGS72055.1
gene_biotype: protein_coding
description:
  Sugar transporter; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: B446_26245
symbol: AGS72057.1
gene_biotype: protein_coding
description:
  Transmembrane protein; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: B446_26250
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: B446_26275
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: B446_26280
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: B446_26285
symbol: ftsH-2
gene_biotype: protein_coding
description:
  Cell division protein FtsH-like protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: B446_26310
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: B446_26315
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine37-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: B446_26320
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: B446_26355
symbol: AGS72079.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: B446_26365
symbol: AGS72081.1
gene_biotype: protein_coding
description:
  DNA processing Smf-family protein; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: B446_26370
symbol: AGS72082.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: B446_26390
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: B446_26400
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: B446_26460
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: B446_26465
symbol: AGS72101.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG4143 ABC-type thiamine transport system, periplasmic component.


ensembl_gene_id: B446_26475
symbol: fbpC
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: B446_26510
symbol: AGS72110.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_26570
symbol: AGS72122.1
gene_biotype: protein_coding
description:
  ABC transporter polyamine-binding lipoprotein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: B446_26575
symbol: potA-3
gene_biotype: protein_coding
description:
  Polyamine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: B446_26580
symbol: AGS72124.1
gene_biotype: protein_coding
description:
  Polyamine ABC-transporter integral membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: B446_26585
symbol: AGS72125.1
gene_biotype: protein_coding
description:
  Polyamine transporter; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: B446_26610
symbol: AGS72130.1
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_26640
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: B446_26650
symbol: ispG1
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: B446_26665
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyla [...]


ensembl_gene_id: B446_26685
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: B446_26690
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: B446_26695
symbol: AGS72147.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.


ensembl_gene_id: B446_26700
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: B446_26710
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: B446_26715
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: B446_26720
symbol: AGS72152.1
gene_biotype: protein_coding
description:
  Large Pro/Ala/Gly-rich protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: B446_26725
symbol: AGS72153.1
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.


ensembl_gene_id: B446_26825
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: B446_26830
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: B446_26840
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: B446_26860
symbol: thyX
gene_biotype: protein_coding
description:
  FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: B446_26870
symbol: rnj
gene_biotype: protein_coding
description:
  Hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: B446_26895
symbol: AGS72187.1
gene_biotype: protein_coding
description:
  COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: B446_26905
symbol: rimO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: B446_26925
symbol: AGS72193.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family.


ensembl_gene_id: B446_26985
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: B446_27025
symbol: AGS72213.1
gene_biotype: protein_coding
description:
  Glutamate binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: B446_27030
symbol: AGS72214.1
gene_biotype: protein_coding
description:
  Glutamate uptake system ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: B446_27070
symbol: AGS72222.1
gene_biotype: protein_coding
description:
  Putative MerR family transcriptional regulator/peroxidase; COG0789 Predicted transcriptional regulators.


ensembl_gene_id: B446_27080
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: B446_27100
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: B446_27110
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: B446_27125
symbol: hflX
gene_biotype: protein_coding
description:
  ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: B446_27135
symbol: AGS72235.1
gene_biotype: protein_coding
description:
  Class III aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_27155
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: B446_27160
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: B446_27165
symbol: AGS72241.1
gene_biotype: protein_coding
description:
  Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: B446_27180
symbol: AGS72244.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: B446_27240
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: B446_27255
symbol: AGS72259.1
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.


ensembl_gene_id: B446_27290
symbol: AGS72266.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: B446_27295
symbol: AGS72267.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: B446_27300
symbol: AGS72268.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: B446_27310
symbol: AGS72270.1
gene_biotype: protein_coding
description:
  Two-component sensor; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: B446_27415
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: B446_27460
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: B446_27505
symbol: AGS72309.1
gene_biotype: protein_coding
description:
  COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: B446_27555
symbol: AGS72319.1
gene_biotype: protein_coding
description:
  NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: B446_27575
symbol: tmk-2
gene_biotype: protein_coding
description:
  dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: B446_27665
symbol: AGS72341.1
gene_biotype: protein_coding
description:
  Membrane ATPase/protein kinase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: B446_27700
symbol: AGS72348.1
gene_biotype: protein_coding
description:
  bldA-regulated nucleotide binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: B446_27745
symbol: AGS72357.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: B446_27760
symbol: AGS72360.1
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: B446_27820
symbol: AGS72372.1
gene_biotype: protein_coding
description:
  salicylyl-CoA 5-hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: B446_27915
symbol: AGS72391.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase II; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: B446_27925
symbol: fabH-2
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: B446_27935
symbol: AGS72395.1
gene_biotype: protein_coding
description:
  NADPH-flavin oxidoreductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: B446_28050
symbol: AGS72418.1
gene_biotype: protein_coding
description:
  Sugar transporter sugar binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_28055
symbol: AGS72419.1
gene_biotype: protein_coding
description:
  Sugar transporter integral membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: B446_28060
symbol: AGS72420.1
gene_biotype: protein_coding
description:
  Sugar transporter integral membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: B446_28125
symbol: AGS72433.1
gene_biotype: protein_coding
description:
  Response regulator receiver and unknown domain protein; COG4565 Response regulator of citrate/malate metabolism.


ensembl_gene_id: B446_28140
symbol: AGS72436.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: B446_28220
symbol: AGS72452.1
gene_biotype: protein_coding
description:
  COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: B446_28225
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: B446_28280
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: B446_28300
symbol: AGS72468.1
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: B446_28375
symbol: AGS72481.1
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: B446_28405
symbol: AGS72487.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: B446_28415
symbol: AGS72489.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


ensembl_gene_id: B446_28420
symbol: AGS72490.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: B446_28450
symbol: AGS72496.1
gene_biotype: protein_coding
description:
  COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: B446_28460
symbol: tatA-2
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: B446_28585
symbol: AGS72523.1
gene_biotype: protein_coding
description:
  Oleandomycin glycosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.


ensembl_gene_id: B446_28615
symbol: AGS72529.1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase-like domain-containing protein; COG0515 Serine/threonine protein kinase.


ensembl_gene_id: B446_28625
symbol: AGS72531.1
gene_biotype: protein_coding
description:
  Von Willebrand factor type A; COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain.


ensembl_gene_id: B446_28690
symbol: AGS72544.1
gene_biotype: protein_coding
description:
  ABC-type sulfate transporter periplasmic binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: B446_28700
symbol: AGS72546.1
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: B446_28705
symbol: AGS72547.1
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: B446_28715
symbol: AGS72549.1
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: B446_28725
symbol: AGS72551.1
gene_biotype: protein_coding
description:
  COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: B446_28830
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.


ensembl_gene_id: B446_28885
symbol: rsgA-2
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: B446_28925
symbol: AGS72591.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: B446_28965
symbol: AGS72599.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: B446_28970
symbol: AGS72600.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: B446_28975
symbol: AGS72601.1
gene_biotype: protein_coding
description:
  Xanthine dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: B446_29085
symbol: AGS72623.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: B446_29145
symbol: AGS72635.1
gene_biotype: protein_coding
description:
  2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: B446_29170
symbol: AGS72640.1
gene_biotype: protein_coding
description:
  Hydroxyisourate hydrolase; COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: B446_29175
symbol: AGS72641.1
gene_biotype: protein_coding
description:
  Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.


ensembl_gene_id: B446_29180
symbol: AGS72642.1
gene_biotype: protein_coding
description:
  Hydroxydechloroatrazine ethylaminohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: B446_29340
symbol: AGS72674.1
gene_biotype: protein_coding
description:
  ABC transporter sugar binding lipoprotein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_29385
symbol: rnj-2
gene_biotype: protein_coding
description:
  Beta-lactamase domain-containing protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: B446_29405
symbol: AGS72687.1
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_29530
symbol: AGS72712.1
gene_biotype: protein_coding
description:
  Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: B446_29540
symbol: AGS72714.1
gene_biotype: protein_coding
description:
  RNase III inhibitor; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: B446_29640
symbol: AGS72734.1
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: B446_29675
symbol: AGS72741.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_29740
symbol: AGS72754.1
gene_biotype: protein_coding
description:
  COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: B446_29745
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: B446_29845
symbol: AGS72773.1
gene_biotype: protein_coding
description:
  Peptidase U61 LD-carboxypeptidase A; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.


ensembl_gene_id: B446_29860
symbol: AGS72776.1
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase subunit PaaB; COG3460 Uncharacterized enzyme of phenylacetate metabolism.


ensembl_gene_id: B446_29870
symbol: AGS72778.1
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation protein PaaD; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.


ensembl_gene_id: B446_29875
symbol: AGS72779.1
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation NADH oxidoreductase PaaE; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: B446_29945
symbol: AGS72793.1
gene_biotype: protein_coding
description:
  Gas vesicle synthesis protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.


ensembl_gene_id: B446_30005
symbol: AGS72805.1
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: B446_30065
symbol: AGS72817.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component.


ensembl_gene_id: B446_30105
symbol: AGS72825.1
gene_biotype: protein_coding
description:
  COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: B446_30115
symbol: AGS72827.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: B446_30160
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: B446_30385
symbol: AGS72881.1
gene_biotype: protein_coding
description:
  NADP oxidoreductase, coenzyme F420-dependent:6-phosphogluconate dehydrogenase, NAD-binding protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: B446_30455
symbol: AGS72895.1
gene_biotype: protein_coding
description:
  6-phospho-beta-glucosidase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: B446_30505
symbol: AGS72905.1
gene_biotype: protein_coding
description:
  Sugar uptake ABC transporter sugar-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_30515
symbol: AGS72907.1
gene_biotype: protein_coding
description:
  Sugar transporter intracellular portion; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: B446_30560
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: B446_30615
symbol: AGS72927.1
gene_biotype: protein_coding
description:
  Glutathione-dependent aldehyde dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: B446_30670
symbol: AGS72938.1
gene_biotype: protein_coding
description:
  Oxidoreductase (secreted protein); COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: B446_30685
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: B446_30700
symbol: AGS72944.1
gene_biotype: protein_coding
description:
  Fatty acid-CoA racemase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: B446_30725
symbol: AGS72949.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: B446_30765
symbol: AGS72957.1
gene_biotype: protein_coding
description:
  4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme; COG0693 Putative intracellular protease/amidase.


ensembl_gene_id: B446_30780
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: B446_30795
symbol: AGS72963.1
gene_biotype: protein_coding
description:
  Integral membrane transferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: B446_30875
symbol: AGS72979.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: B446_30915
symbol: AGS72987.1
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: B446_30955
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: B446_30960
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: B446_31045
symbol: AGS73013.1
gene_biotype: protein_coding
description:
  beta-ketoadipyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: B446_31105
symbol: AGS73025.1
gene_biotype: protein_coding
description:
  COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain.


ensembl_gene_id: B446_31130
symbol: AGS73030.1
gene_biotype: protein_coding
description:
  ABC transporter integral membrane permease; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: B446_31145
symbol: AGS73033.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter substrate-binding protein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_31150
symbol: AGS73034.1
gene_biotype: protein_coding
description:
  ABC transporter membrane protein; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: B446_31320
symbol: AGS73068.1
gene_biotype: protein_coding
description:
  Oxidoreductase, molybdopterin binding subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: B446_31325
symbol: AGS73069.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: B446_31475
symbol: AGS73099.1
gene_biotype: protein_coding
description:
  PAS/PAC sensor protein; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: B446_31530
symbol: AGS73110.1
gene_biotype: protein_coding
description:
  Oligopeptide transport ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: B446_31535
symbol: AGS73111.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 5 protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: B446_31615
symbol: AGS73127.1
gene_biotype: protein_coding
description:
  Luciferase family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_31640
symbol: hscB
gene_biotype: protein_coding
description:
  Heat shock protein HscB; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: B446_31655
symbol: clpB-2
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: B446_31670
symbol: AGS73138.1
gene_biotype: protein_coding
description:
  Thioredoxin reductase; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: B446_31685
symbol: ssuB-2
gene_biotype: protein_coding
description:
  ABC transporter-like protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: B446_31690
symbol: AGS73142.1
gene_biotype: protein_coding
description:
  Aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: B446_31695
symbol: AGS73143.1
gene_biotype: protein_coding
description:
  FMNH2-dependent monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_31720
symbol: AGS73148.1
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_31725
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: B446_31735
symbol: AGS73151.1
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: B446_31760
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: B446_31770
symbol: AGS73158.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2199 FOG: GGDEF domain; Belongs to the long-chain O-acyltransferase family.


ensembl_gene_id: B446_31780
symbol: AGS73160.1
gene_biotype: protein_coding
description:
  3-ketoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: B446_31810
symbol: AGS73166.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: B446_31975
symbol: AGS73199.1
gene_biotype: protein_coding
description:
  DNA binding ATP-dependent peptidase; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: B446_31980
symbol: AGS73200.1
gene_biotype: protein_coding
description:
  Oxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: B446_32005
symbol: egtD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.


ensembl_gene_id: B446_32010
symbol: egtC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.


ensembl_gene_id: B446_32015
symbol: egtB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.


ensembl_gene_id: B446_32020
symbol: egtA
gene_biotype: protein_coding
description:
  Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.


ensembl_gene_id: B446_32050
symbol: AGS73214.1
gene_biotype: protein_coding
description:
  Oxidoreductase subunit beta; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: B446_32055
symbol: AGS73215.1
gene_biotype: protein_coding
description:
  Oxidoreductase subunit; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: B446_32095
symbol: AGS73223.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: B446_32100
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: B446_32230
symbol: AGS73250.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter amino acid-binding protein; COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: B446_32270
symbol: rbsA-2
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: B446_32275
symbol: AGS73259.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: B446_32285
symbol: AGS73261.1
gene_biotype: protein_coding
description:
  Secreted solute-binding lipoprotein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: B446_32295
symbol: AGS73263.1
gene_biotype: protein_coding
description:
  Prolyl aminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: B446_32420
symbol: AGS73288.1
gene_biotype: protein_coding
description:
  NADH-dehydrogenase; COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit.


ensembl_gene_id: B446_32430
symbol: AGS73290.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, PucR family protein; COG2508 Regulator of polyketide synthase expression.


ensembl_gene_id: B446_32570
symbol: AGS73318.1
gene_biotype: protein_coding
description:
  Sigma-70 region 2 domain-containing protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: B446_32585
symbol: AGS73321.1
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: B446_32640
symbol: AGS73332.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: B446_32645
symbol: AGS73333.1
gene_biotype: protein_coding
description:
  COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: B446_32675
symbol: AGS73339.1
gene_biotype: protein_coding
description:
  Oleoyl-(acyl-carrier-protein) hydrolase; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: B446_32730
symbol: AGS73350.1
gene_biotype: protein_coding
description:
  Cytochrome C oxidase polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: B446_32750
symbol: AGS73354.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: B446_32815
symbol: whiB-8
gene_biotype: protein_coding
description:
  Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: B446_32875
symbol: AGS73379.1
gene_biotype: protein_coding
description:
  FAD-binding molybdopterin dehydrogenase protein; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: B446_32880
symbol: AGS73380.1
gene_biotype: protein_coding
description:
  Molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: B446_32920
symbol: AGS73388.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: B446_33170
symbol: AGS73438.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase/oxidase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: B446_33590
symbol: kirP-2
gene_biotype: protein_coding
description:
  Putative Sfp type phosphopantetheinyl transferase; COG2977 Phosphopantetheinyl transferase component of siderophore synthetase.


ensembl_gene_id: B446_33705
symbol: kirHVI-2
gene_biotype: protein_coding
description:
  Putative phytanoyl-CoA dioxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: B446_34115
symbol: AGS73623.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


