# geneInfo

ensembl_gene_id: H340_00045
symbol: EMF02538.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: H340_00050
symbol: EMF02539.1
gene_biotype: protein_coding
description:
  ABC transporter system integral membrane protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H340_00055
symbol: EMF02540.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H340_00060
symbol: EMF02541.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_00085
symbol: EMF02546.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis-like protein MoeZ; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: H340_00095
symbol: EMF02548.1
gene_biotype: protein_coding
description:
  UbiC transcription regulator-associated domain-containing protein; COG2188 Transcriptional regulators.


ensembl_gene_id: H340_00115
symbol: EMF02552.1
gene_biotype: protein_coding
description:
  COG4149 ABC-type molybdate transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H340_00120
symbol: EMF02553.1
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter periplasmic molybdate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: H340_00145
symbol: EMF02558.1
gene_biotype: protein_coding
description:
  methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding protein; COG3695 Predicted methylated DNA-protein cysteine methyltransferase.


ensembl_gene_id: H340_00160
symbol: EMF02561.1
gene_biotype: protein_coding
description:
  Peptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: H340_00165
symbol: EMF02562.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.


ensembl_gene_id: H340_00185
symbol: whiB
gene_biotype: protein_coding
description:
  Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: H340_00230
symbol: EMF02575.1
gene_biotype: protein_coding
description:
  Putative molybdopterin biosynthesis protein E; COG0314 Molybdopterin converting factor, large subunit.


ensembl_gene_id: H340_00260
symbol: EMF02581.1
gene_biotype: protein_coding
description:
  Fur family ferric uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: H340_00275
symbol: EMF02584.1
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: H340_00285
symbol: EMF02586.1
gene_biotype: protein_coding
description:
  SMR-type multi-drug efflux transporter; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: H340_00290
symbol: rsgA
gene_biotype: protein_coding
description:
  Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: H340_00295
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: H340_00315
symbol: EMF02592.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H340_00340
symbol: def
gene_biotype: protein_coding
description:
  Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: H340_00350
symbol: EMF02599.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: H340_00355
symbol: EMF02600.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: H340_00390
symbol: EMF02607.1
gene_biotype: protein_coding
description:
  Sugar transporter sugar binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: H340_00395
symbol: EMF02608.1
gene_biotype: protein_coding
description:
  Sugar transporter integral membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: H340_00410
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.


ensembl_gene_id: H340_00415
symbol: EMF02612.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_00430
symbol: whiB-2
gene_biotype: protein_coding
description:
  WhiB transcription regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: H340_00435
symbol: EMF02616.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: H340_00445
symbol: EMF02618.1
gene_biotype: protein_coding
description:
  COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: H340_00465
symbol: EMF02622.1
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: H340_00490
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: H340_00495
symbol: EMF02628.1
gene_biotype: protein_coding
description:
  Putative streptomycin-6-phosphate phosphatase; COG1785 Alkaline phosphatase; Belongs to the alkaline phosphatase family.


ensembl_gene_id: H340_00500
symbol: tatA-2
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: H340_00575
symbol: EMF02644.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: H340_00585
symbol: EMF02646.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H340_00685
symbol: kgd
gene_biotype: protein_coding
description:
  Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.


ensembl_gene_id: H340_00695
symbol: EMF02668.1
gene_biotype: protein_coding
description:
  Winged helix family two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_00715
symbol: EMF02672.1
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: H340_00720
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: H340_00750
symbol: EMF02679.1
gene_biotype: protein_coding
description:
  Aldo-keto reductase yakc; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: H340_00904
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: H340_00939
symbol: EMF02370.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: H340_00969
symbol: EMF02376.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: H340_00979
symbol: EMF02378.1
gene_biotype: protein_coding
description:
  COG2217 Cation transport ATPase; Lead, cadmium, zinc and mercury transporting ATPase; Copper-translocating P-type ATPase.


ensembl_gene_id: H340_00999
symbol: EMF02382.1
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein afsQ1; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_01009
symbol: EMF02384.1
gene_biotype: protein_coding
description:
  COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: H340_01029
symbol: egtA
gene_biotype: protein_coding
description:
  Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.


ensembl_gene_id: H340_01034
symbol: egtB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.


ensembl_gene_id: H340_01039
symbol: egtC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.


ensembl_gene_id: H340_01044
symbol: egtD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.


ensembl_gene_id: H340_01079
symbol: EMF02398.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: H340_01109
symbol: EMF02402.1
gene_biotype: protein_coding
description:
  protein-L-isoaspartate(D-aspartate) O-methyltransferase; COG2518 Protein-L-isoaspartate carboxylmethyltransferase.


ensembl_gene_id: H340_01169
symbol: thyX
gene_biotype: protein_coding
description:
  FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: H340_01494
symbol: EMF02479.1
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: H340_01574
symbol: EMF02495.1
gene_biotype: protein_coding
description:
  High-affinity nickel-transport protein; COG3376 High-affinity nickel permease; Belongs to the NiCoT transporter (TC 2.A.52) family.


ensembl_gene_id: H340_01644
symbol: EMF02509.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H340_01649
symbol: cobN
gene_biotype: protein_coding
description:
  Cobaltochelatase subunit CobN; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: H340_01679
symbol: cbiD
gene_biotype: protein_coding
description:
  cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: H340_01714
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: H340_01804
symbol: EMF02195.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: H340_01829
symbol: EMF02200.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: H340_01849
symbol: EMF02204.1
gene_biotype: protein_coding
description:
  ATP/GTP-binding protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: H340_01874
symbol: EMF02209.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: H340_01884
symbol: EMF02211.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_01904
symbol: EMF02215.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.


ensembl_gene_id: H340_01924
symbol: EMF02219.1
gene_biotype: protein_coding
description:
  Flavin-dependent reductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H340_01934
symbol: EMF02221.1
gene_biotype: protein_coding
description:
  Putative 1-acylglycerol-3-phosphate O-acyltransferase; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.


ensembl_gene_id: H340_01944
symbol: EMF02223.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_01959
symbol: EMF02226.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: H340_02039
symbol: EMF02242.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_02049
symbol: EMF02244.1
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: H340_02069
symbol: EMF02248.1
gene_biotype: protein_coding
description:
  Membrane ATPase/protein kinase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: H340_02074
symbol: EMF02249.1
gene_biotype: protein_coding
description:
  COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit; overlaps another CDS with the same product name.


ensembl_gene_id: H340_02119
symbol: glnE
gene_biotype: protein_coding
description:
  Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]


ensembl_gene_id: H340_02184
symbol: EMF02271.1
gene_biotype: protein_coding
description:
  Sterol 3-beta-glucosyltransferase; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: H340_02194
symbol: EMF02273.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_02204
symbol: EMF02275.1
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase-like protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: H340_02239
symbol: nadE-2
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: H340_02289
symbol: EMF02292.1
gene_biotype: protein_coding
description:
  EmrB/QacA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: H340_02294
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: H340_02299
symbol: EMF02294.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: H340_02349
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: H340_02394
symbol: EMF02313.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_02429
symbol: EMF02320.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: H340_02454
symbol: EMF02325.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family.


ensembl_gene_id: H340_02529
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: H340_02544
symbol: EMF02343.1
gene_biotype: protein_coding
description:
  Tat-translocated protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: H340_02609
symbol: EMF02085.1
gene_biotype: protein_coding
description:
  MutT/nudix family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: H340_02704
symbol: EMF02104.1
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: H340_02729
symbol: EMF02109.1
gene_biotype: protein_coding
description:
  Molecular chaperone GroES; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H340_02834
symbol: EMF02130.1
gene_biotype: protein_coding
description:
  Peptidase S9 prolyl oligopeptidase active site domain protein; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.


ensembl_gene_id: H340_02854
symbol: EMF02134.1
gene_biotype: protein_coding
description:
  Exoenzymes regulatory protein AepA precursor; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.


ensembl_gene_id: H340_02869
symbol: EMF02137.1
gene_biotype: protein_coding
description:
  Putative LuxR-family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_02924
symbol: EMF02148.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: H340_02929
symbol: EMF02149.1
gene_biotype: protein_coding
description:
  Oxidoreductase, molybdopterin binding subunit; COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.


ensembl_gene_id: H340_02934
symbol: EMF02150.1
gene_biotype: protein_coding
description:
  Oxidoreductase, iron-sulfur binding subunit; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: H340_02969
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: H340_02974
symbol: EMF02158.1
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: H340_02979
symbol: EMF02159.1
gene_biotype: protein_coding
description:
  COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family.


ensembl_gene_id: H340_03009
symbol: EMF02165.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: H340_03014
symbol: EMF02166.1
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: H340_03029
symbol: EMF02169.1
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_03049
symbol: EMF02173.1
gene_biotype: protein_coding
description:
  FAD-binding monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_03064
symbol: EMF02176.1
gene_biotype: protein_coding
description:
  AfsR-like transcriptional regulator; COG3629 DNA-binding transcriptional activator of the SARP family.


ensembl_gene_id: H340_03069
symbol: EMF02177.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG3251 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: H340_03099
symbol: EMF02183.1
gene_biotype: protein_coding
description:
  Natural resistance-associated macrophage protein; COG1914 Mn2+ and Fe2+ transporters of the NRAMP family.


ensembl_gene_id: H340_03159
symbol: EMF01987.1
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-[acyl-carrier-protein] reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_03169
symbol: EMF01989.1
gene_biotype: protein_coding
description:
  beta-hydroxyacyl-ACP dehydratase; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases.


ensembl_gene_id: H340_03184
symbol: EMF01992.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: H340_03224
symbol: EMF02000.1
gene_biotype: protein_coding
description:
  Valine-pyruvate aminotransferase; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: H340_03289
symbol: EMF02013.1
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_03299
symbol: EMF02015.1
gene_biotype: protein_coding
description:
  Putative two component system response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_03309
symbol: EMF02017.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: H340_03389
symbol: EMF02033.1
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactonase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_03429
symbol: EMF02041.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H340_03434
symbol: EMF02042.1
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: H340_03474
symbol: EMF02050.1
gene_biotype: protein_coding
description:
  Class III aminotransferase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_03484
symbol: EMF02052.1
gene_biotype: protein_coding
description:
  COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_03494
symbol: EMF02054.1
gene_biotype: protein_coding
description:
  CRISPR-associated protein, Cas2 family; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.


ensembl_gene_id: H340_03499
symbol: EMF02055.1
gene_biotype: protein_coding
description:
  CRISPR-associated Cas1 family protein; COG1518 Uncharacterized protein predicted to be involved in DNA repair.


ensembl_gene_id: H340_03544
symbol: EMF02064.1
gene_biotype: protein_coding
description:
  Putative inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: H340_03574
symbol: EMF02070.1
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: H340_03599
symbol: EMF02075.1
gene_biotype: protein_coding
description:
  Putative MerR family transcriptional regulator/peroxidase; COG0789 Predicted transcriptional regulators.


ensembl_gene_id: H340_03674
symbol: EMF01885.1
gene_biotype: protein_coding
description:
  Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: H340_03704
symbol: EMF01891.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: H340_03709
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: H340_03949
symbol: EMF01940.1
gene_biotype: protein_coding
description:
  Glycosyl transferase family protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).


ensembl_gene_id: H340_03954
symbol: whiB-3
gene_biotype: protein_coding
description:
  WhiB-family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: H340_03994
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: H340_04024
symbol: nhaA
gene_biotype: protein_coding
description:
  pH-dependent sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: H340_04029
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: H340_04094
symbol: EMF01969.1
gene_biotype: protein_coding
description:
  Helicase/secretion neighborhood DEAH-box helicase; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: H340_04099
symbol: EMF01970.1
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: H340_04109
symbol: hppA
gene_biotype: protein_coding
description:
  Membrane-bound proton-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: H340_04119
symbol: EMF01974.1
gene_biotype: protein_coding
description:
  rRNA or tRNA methyltransferase; COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily.


ensembl_gene_id: H340_04133
symbol: EMF01765.1
gene_biotype: protein_coding
description:
  parB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: H340_04143
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: H340_04158
symbol: EMF01770.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: H340_04163
symbol: rnpA
gene_biotype: protein_coding
description:
  RNase P component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: H340_04173
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: H340_04178
symbol: EMF01774.1
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: H340_04188
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: H340_04193
symbol: EMF01777.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives; Belongs to the UPF0232 family.


ensembl_gene_id: H340_04198
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: H340_04203
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: H340_04248
symbol: EMF01788.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: H340_04313
symbol: EMF01801.1
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: H340_04353
symbol: EMF01809.1
gene_biotype: protein_coding
description:
  Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: H340_04443
symbol: EMF01827.1
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation NADH oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: H340_04448
symbol: EMF01828.1
gene_biotype: protein_coding
description:
  Putative phenylacetic acid degradation protein; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; overlaps another CDS with the same product name.


ensembl_gene_id: H340_04453
symbol: EMF01829.1
gene_biotype: protein_coding
description:
  Putative phenylacetic acid degradation protein; COG3396 Uncharacterized conserved protein; overlaps another CDS with the same product name.


ensembl_gene_id: H340_04503
symbol: EMF01839.1
gene_biotype: protein_coding
description:
  E1-alpha branched-chain alpha keto acid dehydrogenase; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: H340_04508
symbol: EMF01840.1
gene_biotype: protein_coding
description:
  Transketolase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: H340_04513
symbol: EMF01841.1
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: H340_04518
symbol: EMF01842.1
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: H340_04543
symbol: EMF01847.1
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase, PIG3 family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H340_04583
symbol: EMF01855.1
gene_biotype: protein_coding
description:
  COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: H340_04588
symbol: EMF01856.1
gene_biotype: protein_coding
description:
  Transketolase central subunit; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: H340_04714
symbol: EMF01675.1
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: H340_04719
symbol: EMF01676.1
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H340_04764
symbol: sbcD
gene_biotype: protein_coding
description:
  Putative exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: H340_04819
symbol: EMF01696.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: H340_04829
symbol: EMF01698.1
gene_biotype: protein_coding
description:
  Siderophore binding protein; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.


ensembl_gene_id: H340_04869
symbol: EMF01706.1
gene_biotype: protein_coding
description:
  Putative alkanal monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_04879
symbol: EMF01708.1
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_04909
symbol: EMF01714.1
gene_biotype: protein_coding
description:
  NADPH-ferredoxin reductase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: H340_04944
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: H340_05019
symbol: EMF01736.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H340_05034
symbol: EMF01739.1
gene_biotype: protein_coding
description:
  ABC transporter ATPase/permease; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H340_05114
symbol: EMF01755.1
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: H340_05149
symbol: EMF01762.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.


ensembl_gene_id: H340_05204
symbol: EMF01578.1
gene_biotype: protein_coding
description:
  Daunorubicin resistance ABC transporter ATPase subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: H340_05259
symbol: EMF01589.1
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: H340_05284
symbol: EMF01594.1
gene_biotype: protein_coding
description:
  eryBIII NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase; COG0500 SAM-dependent methyltransferases.


ensembl_gene_id: H340_05294
symbol: EMF01596.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes.


ensembl_gene_id: H340_05339
symbol: EMF01605.1
gene_biotype: protein_coding
description:
  TAP domain-containing protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_05379
symbol: EMF01613.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: H340_05394
symbol: EMF01616.1
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: H340_05434
symbol: EMF01624.1
gene_biotype: protein_coding
description:
  NAD-dependent glycerol-3-phosphate dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: H340_05489
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: H340_05504
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: H340_05509
symbol: EMF01639.1
gene_biotype: protein_coding
description:
  COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: H340_05514
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein ftsH-like protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: H340_05544
symbol: EMF01646.1
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: H340_05549
symbol: EMF01647.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: H340_05559
symbol: EMF01649.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


ensembl_gene_id: H340_05564
symbol: EMF01650.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: H340_05574
symbol: EMF01652.1
gene_biotype: protein_coding
description:
  Glycine/betaine ABC transporter substrate-binding protein; COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: H340_05584
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: H340_05599
symbol: EMF01657.1
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_05604
symbol: EMF01658.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H340_05609
symbol: EMF01659.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_05629
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: H340_05644
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: H340_05671
symbol: EMF01500.1
gene_biotype: protein_coding
description:
  Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: H340_05686
symbol: EMF01503.1
gene_biotype: protein_coding
description:
  CRP-like regulatory protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H340_05696
symbol: EMF01505.1
gene_biotype: protein_coding
description:
  COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: H340_05721
symbol: EMF01510.1
gene_biotype: protein_coding
description:
  Family 1 extracellular solute-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: H340_05806
symbol: EMF01527.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: H340_05811
symbol: EMF01528.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: H340_05871
symbol: EMF01540.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_05881
symbol: EMF01542.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: H340_05886
symbol: EMF01543.1
gene_biotype: protein_coding
description:
  Monooxygenase FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_05901
symbol: EMF01546.1
gene_biotype: protein_coding
description:
  Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: H340_05921
symbol: EMF01550.1
gene_biotype: protein_coding
description:
  COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: H340_05991
symbol: EMF01564.1
gene_biotype: protein_coding
description:
  COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: H340_06076
symbol: EMF01434.1
gene_biotype: protein_coding
description:
  Fatty acid-CoA racemase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: H340_06196
symbol: EMF01456.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H340_06201
symbol: EMF01457.1
gene_biotype: protein_coding
description:
  Bcr/CflA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: H340_06206
symbol: EMF01458.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4779 ABC-type enterobactin transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H340_06231
symbol: EMF01463.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding membrane translocator, AmfB; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H340_06246
symbol: EMF01466.1
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: H340_06261
symbol: EMF01469.1
gene_biotype: protein_coding
description:
  Serine phosphatase RsbU regulator of sigma subunit-like protein; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: H340_06281
symbol: EMF01473.1
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_06296
symbol: EMF01476.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: H340_06321
symbol: EMF01481.1
gene_biotype: protein_coding
description:
  Nitrilotriacetate monooxygenase component B protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H340_06366
symbol: EMF01490.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: H340_06406
symbol: EMF01357.1
gene_biotype: protein_coding
description:
  ATPase AAA; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: H340_06426
symbol: EMF01361.1
gene_biotype: protein_coding
description:
  Tellurium resistance; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: H340_06491
symbol: EMF01374.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator of N-Acetylglucosamine utilization, GntR family protein; COG2188 Transcriptional regulators.


ensembl_gene_id: H340_06506
symbol: EMF01377.1
gene_biotype: protein_coding
description:
  COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_06521
symbol: EMF01380.1
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: H340_06541
symbol: EMF01384.1
gene_biotype: protein_coding
description:
  COG0076 Glutamate decarboxylase and related PLP-dependent proteins; Belongs to the group II decarboxylase family.


ensembl_gene_id: H340_06586
symbol: EMF01393.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_06591
symbol: EMF01394.1
gene_biotype: protein_coding
description:
  COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: H340_06641
symbol: EMF01404.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_06656
symbol: EMF01407.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_06696
symbol: EMF01415.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.


ensembl_gene_id: H340_06736
symbol: EMF01278.1
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_06746
symbol: EMF01280.1
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_06756
symbol: EMF01282.1
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: H340_06781
symbol: EMF01287.1
gene_biotype: protein_coding
description:
  Flavin reductase domain-containing protein FMN-binding protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H340_06966
symbol: rbsK
gene_biotype: protein_coding
description:
  PfkB domain-containing protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: H340_06981
symbol: rbsA
gene_biotype: protein_coding
description:
  ABC transporter; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: H340_07021
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: H340_07026
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: H340_07156
symbol: EMF01214.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H340_07176
symbol: EMF01218.1
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: H340_07211
symbol: EMF01225.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.


ensembl_gene_id: H340_07216
symbol: EMF01226.1
gene_biotype: protein_coding
description:
  Amino acid adenylation protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_07236
symbol: EMF01230.1
gene_biotype: protein_coding
description:
  SARP family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_07291
symbol: EMF01241.1
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: H340_07441
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: H340_07446
symbol: EMF01272.1
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: H340_07456
symbol: EMF01274.1
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; COG0770 UDP-N-acetylmuramyl pentapeptide synthase.


ensembl_gene_id: H340_07461
symbol: EMF01275.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_07466
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: H340_07471
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis.


ensembl_gene_id: H340_07488
symbol: EMF01128.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD-binding domain-containing protein; COG1017 Hemoglobin-like flavoprotein; Belongs to the globin family.


ensembl_gene_id: H340_07538
symbol: kptA
gene_biotype: protein_coding
description:
  RNA 2'-phosphotransferase-like protein; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.


ensembl_gene_id: H340_07558
symbol: rlmG
gene_biotype: protein_coding
description:
  rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: H340_07683
symbol: EMF01167.1
gene_biotype: protein_coding
description:
  Nitrite reductase (NAD(P)H) large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: H340_07693
symbol: EMF01169.1
gene_biotype: protein_coding
description:
  Assimilatory nitrate reductase catalytic subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: H340_07698
symbol: EMF01170.1
gene_biotype: protein_coding
description:
  Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase.


ensembl_gene_id: H340_07708
symbol: EMF01172.1
gene_biotype: protein_coding
description:
  Prolyl aminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: H340_07808
symbol: EMF01192.1
gene_biotype: protein_coding
description:
  COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; G6PDH family.


ensembl_gene_id: H340_07883
symbol: EMF01207.1
gene_biotype: protein_coding
description:
  Bifunctional synthase/transferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: H340_07908
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: H340_07913
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: H340_07918
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: H340_07923
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: H340_08003
symbol: EMF01072.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H340_08018
symbol: htpX
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: H340_08023
symbol: nuoN
gene_biotype: protein_coding
description:
  NAD(P)H-quinone oxidoreductase subunit 2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: H340_08033
symbol: EMF01078.1
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: H340_08038
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: H340_08043
symbol: EMF01080.1
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 6; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H340_08048
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit NuoI2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H340_08053
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: H340_08063
symbol: nuoB
gene_biotype: protein_coding
description:
  NAD(P)H-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H340_08068
symbol: nuoA
gene_biotype: protein_coding
description:
  NAD(P)H-quinone oxidoreductase subunit 3; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: H340_08083
symbol: EMF01088.1
gene_biotype: protein_coding
description:
  LuxR family two component transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_08088
symbol: EMF01089.1
gene_biotype: protein_coding
description:
  Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.


ensembl_gene_id: H340_08093
symbol: EMF01090.1
gene_biotype: protein_coding
description:
  COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.


ensembl_gene_id: H340_08113
symbol: EMF01094.1
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: H340_08143
symbol: EMF01100.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H340_08148
symbol: nuoN-2
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: H340_08163
symbol: nuoK-2
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: H340_08168
symbol: EMF01105.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H340_08173
symbol: nuoI-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H340_08178
symbol: nuoH-2
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: H340_08183
symbol: EMF01108.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: H340_08188
symbol: EMF01109.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: H340_08198
symbol: nuoD-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: H340_08203
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: H340_08208
symbol: nuoB-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H340_08213
symbol: nuoA-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: H340_08243
symbol: EMF01120.1
gene_biotype: protein_coding
description:
  Microsomal epoxide hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_08263
symbol: EMF01124.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, EmrB/QacA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: H340_08281
symbol: EMF00989.1
gene_biotype: protein_coding
description:
  Putative peptide ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_08286
symbol: EMF00990.1
gene_biotype: protein_coding
description:
  Peptide ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_08296
symbol: EMF00992.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter substrate-binding protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H340_08321
symbol: EMF00997.1
gene_biotype: protein_coding
description:
  COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_08326
symbol: EMF00998.1
gene_biotype: protein_coding
description:
  COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_08336
symbol: EMF01000.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H340_08341
symbol: EMF01001.1
gene_biotype: protein_coding
description:
  Putative peptide ABC transporter substrate-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: H340_08416
symbol: EMF01016.1
gene_biotype: protein_coding
description:
  Addiction module antitoxin; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system.


ensembl_gene_id: H340_08431
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: H340_08446
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: H340_08456
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: H340_08461
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: H340_08491
symbol: EMF01031.1
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: H340_08501
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: H340_08571
symbol: ahpD
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.


ensembl_gene_id: H340_08586
symbol: EMF01050.1
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: H340_08591
symbol: EMF01051.1
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: H340_08596
symbol: EMF01052.1
gene_biotype: protein_coding
description:
  Putative ion-channel protein; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: H340_08641
symbol: EMF00931.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: H340_08706
symbol: EMF00944.1
gene_biotype: protein_coding
description:
  Histidine triad (HIT) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: H340_08791
symbol: EMF00961.1
gene_biotype: protein_coding
description:
  COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: H340_08891
symbol: ftsH-2
gene_biotype: protein_coding
description:
  Microtubule-severing ATPase; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: H340_08916
symbol: metN
gene_biotype: protein_coding
description:
  ABC transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H340_08921
symbol: EMF00987.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: H340_08976
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: H340_08991
symbol: EMF00867.1
gene_biotype: protein_coding
description:
  Putative dehydrogenase (modular protein); COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H340_09106
symbol: EMF00890.1
gene_biotype: protein_coding
description:
  Puromycin N-acetyltransferase, putative; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: H340_09116
symbol: EMF00892.1
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: H340_09151
symbol: EMF00899.1
gene_biotype: protein_coding
description:
  Sugar (and other) transporter family protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: H340_09241
symbol: EMF00917.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: H340_09285
symbol: metN-2
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H340_09310
symbol: cobT-2
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: H340_09315
symbol: EMF00797.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: H340_09350
symbol: EMF00804.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: H340_09405
symbol: EMF00815.1
gene_biotype: protein_coding
description:
  HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: H340_09430
symbol: EMF00820.1
gene_biotype: protein_coding
description:
  Membrane transferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H340_09455
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: H340_09460
symbol: pdxT
gene_biotype: protein_coding
description:
  Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: H340_09470
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: H340_09475
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: H340_09480
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: H340_09490
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: H340_09495
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: H340_09500
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: H340_09505
symbol: EMF00835.1
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase I SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: H340_09535
symbol: EMF00841.1
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: H340_09545
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: H340_09560
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: H340_09565
symbol: EMF00847.1
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: H340_09575
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: H340_09585
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: H340_09590
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: H340_09595
symbol: aroB
gene_biotype: protein_coding
description:
  Shikimate kinase and 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: H340_09600
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: H340_09715
symbol: EMF00748.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H340_09745
symbol: EMF00754.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_09770
symbol: EMF00759.1
gene_biotype: protein_coding
description:
  Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.


ensembl_gene_id: H340_09775
symbol: EMF00760.1
gene_biotype: protein_coding
description:
  Hydroxydechloroatrazine ethylaminohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: H340_09810
symbol: EMF00767.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_09875
symbol: EMF00780.1
gene_biotype: protein_coding
description:
  ABC transporter sugar binding lipoprotein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: H340_09880
symbol: EMF00781.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: H340_09905
symbol: EMF00786.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]


ensembl_gene_id: H340_09935
symbol: EMF00668.1
gene_biotype: protein_coding
description:
  NLP/P60 family protein (secreted protein); COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: H340_09955
symbol: EMF00672.1
gene_biotype: protein_coding
description:
  Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: H340_10015
symbol: EMF00684.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family with aminotransferase domain-containing protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: H340_10070
symbol: EMF00695.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: H340_10160
symbol: EMF00713.1
gene_biotype: protein_coding
description:
  phenylacetate:CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: H340_10235
symbol: EMF00634.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; overlaps another CDS with the same product name.


ensembl_gene_id: H340_10280
symbol: EMF00643.1
gene_biotype: protein_coding
description:
  Phosphonoacetate hydrolase; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: H340_10375
symbol: EMF00662.1
gene_biotype: protein_coding
description:
  Putative ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: H340_10405
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: H340_10410
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: H340_10430
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: H340_10465
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: H340_10480
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: H340_10485
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: H340_10495
symbol: fbiD
gene_biotype: protein_coding
description:
  Hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.


ensembl_gene_id: H340_10505
symbol: EMF00589.1
gene_biotype: protein_coding
description:
  Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: H340_10515
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: H340_10520
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: H340_10545
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: H340_10550
symbol: EMF00598.1
gene_biotype: protein_coding
description:
  Ureidoglycolate lyase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H340_10565
symbol: EMF00601.1
gene_biotype: protein_coding
description:
  Roadblock/LC7 family protein; COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid.


ensembl_gene_id: H340_10625
symbol: EMF00613.1
gene_biotype: protein_coding
description:
  Alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: H340_10640
symbol: EMF00616.1
gene_biotype: protein_coding
description:
  Putative methylmalonyl-CoA decarboxylase subunit alpha; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).


ensembl_gene_id: H340_10655
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.


ensembl_gene_id: H340_10840
symbol: EMF00531.1
gene_biotype: protein_coding
description:
  Membrane-flanked domain-containing protein; COG3428 Predicted membrane protein; overlaps another CDS with the same product name.


ensembl_gene_id: H340_10845
symbol: EMF00532.1
gene_biotype: protein_coding
description:
  Membrane-flanked domain-containing protein; COG3402 Uncharacterized conserved protein; overlaps another CDS with the same product name.


ensembl_gene_id: H340_10890
symbol: EMF00541.1
gene_biotype: protein_coding
description:
  Lipase class 2; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: H340_10945
symbol: recD2
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: H340_11010
symbol: EMF00565.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H340_11035
symbol: EMF00462.1
gene_biotype: protein_coding
description:
  SEC-C motif domain-containing protein; COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase).


ensembl_gene_id: H340_11065
symbol: EMF00468.1
gene_biotype: protein_coding
description:
  Putative peptidase S12 family protein; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: H340_11075
symbol: EMF00470.1
gene_biotype: protein_coding
description:
  Sugar nucleotidyltransferase (glucose-1-phosphate thymidylyltransferase) 2; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: H340_11210
symbol: EMF00497.1
gene_biotype: protein_coding
description:
  Putative anti-anti-sigma-factor; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: H340_11215
symbol: tadA
gene_biotype: protein_coding
description:
  Zinc-binding CMP/dCMP deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: H340_11230
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: H340_11295
symbol: EMF00399.1
gene_biotype: protein_coding
description:
  Integral membrane protein; COG0841 Cation/multidrug efflux pump; overlaps another CDS with the same product name.


ensembl_gene_id: H340_11300
symbol: EMF00400.1
gene_biotype: protein_coding
description:
  Integral membrane protein; COG2898 Uncharacterized conserved protein; overlaps another CDS with the same product name.


ensembl_gene_id: H340_11305
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: H340_11310
symbol: EMF00402.1
gene_biotype: protein_coding
description:
  Cobalbumin biosynthesis protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.


ensembl_gene_id: H340_11365
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: H340_11370
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: H340_11380
symbol: EMF00416.1
gene_biotype: protein_coding
description:
  cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; COG2109 ATP:corrinoid adenosyltransferase.


ensembl_gene_id: H340_11385
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: H340_11395
symbol: EMF00419.1
gene_biotype: protein_coding
description:
  Molybdopterin binding aldehyde oxidase and xanthine dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: H340_11405
symbol: EMF00421.1
gene_biotype: protein_coding
description:
  (2Fe-2S)-binding domain-containing protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: H340_11410
symbol: EMF00422.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: H340_11450
symbol: EMF00430.1
gene_biotype: protein_coding
description:
  Stress protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: H340_11465
symbol: EMF00433.1
gene_biotype: protein_coding
description:
  Luciferase oxidoreductase, group 1; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_11470
symbol: EMF00434.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes.


ensembl_gene_id: H340_11570
symbol: EMF00454.1
gene_biotype: protein_coding
description:
  Male sterility domain-containing protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: H340_11615
symbol: EMF00354.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H340_11625
symbol: EMF00356.1
gene_biotype: protein_coding
description:
  Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.


ensembl_gene_id: H340_11675
symbol: EMF00366.1
gene_biotype: protein_coding
description:
  DsbA oxidoreductase; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: H340_11680
symbol: EMF00367.1
gene_biotype: protein_coding
description:
  Major facilitator superfamily (MFS) multidrug efflux pump; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: H340_11710
symbol: EMF00373.1
gene_biotype: protein_coding
description:
  AfsR-like transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_11715
symbol: EMF00374.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_11835
symbol: EMF00291.1
gene_biotype: protein_coding
description:
  Putative acetoin utilization protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: H340_11880
symbol: rex
gene_biotype: protein_coding
description:
  Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: H340_11885
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: H340_11890
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: H340_11895
symbol: EMF00303.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase; COG0007 Uroporphyrinogen-III methylase.


ensembl_gene_id: H340_11945
symbol: EMF00313.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H340_11985
symbol: EMF00321.1
gene_biotype: protein_coding
description:
  Putative cytochrome assembly protein; COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component.


ensembl_gene_id: H340_12010
symbol: EMF00326.1
gene_biotype: protein_coding
description:
  Menaquinone biosynthesis decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: H340_12015
symbol: ubiA
gene_biotype: protein_coding
description:
  Prenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: H340_12040
symbol: mqnE
gene_biotype: protein_coding
description:
  Menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.


ensembl_gene_id: H340_12045
symbol: EMF00333.1
gene_biotype: protein_coding
description:
  GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: H340_12055
symbol: EMF00335.1
gene_biotype: protein_coding
description:
  COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: H340_12105
symbol: mqnA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: H340_12150
symbol: EMF00242.1
gene_biotype: protein_coding
description:
  NAD-binding protein 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase.


ensembl_gene_id: H340_12195
symbol: EMF00251.1
gene_biotype: protein_coding
description:
  Lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: H340_12200
symbol: EMF00252.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: H340_12205
symbol: EMF00253.1
gene_biotype: protein_coding
description:
  COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H340_12210
symbol: EMF00254.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter integral membrane protein; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H340_12215
symbol: EMF00255.1
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: H340_12245
symbol: add
gene_biotype: protein_coding
description:
  COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: H340_12280
symbol: EMF00268.1
gene_biotype: protein_coding
description:
  Sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H340_12305
symbol: EMF00273.1
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: H340_12370
symbol: EMF00286.1
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: H340_12380
symbol: EMF00288.1
gene_biotype: protein_coding
description:
  Flavoprotein disulfide reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: H340_12425
symbol: EMF00194.1
gene_biotype: protein_coding
description:
  Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: H340_12445
symbol: EMF00198.1
gene_biotype: protein_coding
description:
  COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: H340_12450
symbol: mshD
gene_biotype: protein_coding
description:
  Acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.


ensembl_gene_id: H340_12470
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: H340_12495
symbol: mshA
gene_biotype: protein_coding
description:
  D-inositol-3-phosphate glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.


ensembl_gene_id: H340_12525
symbol: EMF00214.1
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_12540
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: H340_12545
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: H340_12570
symbol: EMF00223.1
gene_biotype: protein_coding
description:
  TrmH family RNA methyltransferase; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: H340_12580
symbol: EMF00225.1
gene_biotype: protein_coding
description:
  Guanyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: H340_12590
symbol: EMF00227.1
gene_biotype: protein_coding
description:
  Putative maltose/cellubiose ABC transporter ATP-binding subunit; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_12635
symbol: EMF00236.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: H340_12692
symbol: EMF00142.1
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: H340_12807
symbol: EMF00165.1
gene_biotype: protein_coding
description:
  RNA-binding S4 domain-containing protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).


ensembl_gene_id: H340_12842
symbol: EMF00172.1
gene_biotype: protein_coding
description:
  Phosphotriesterase-family protein; COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold.


ensembl_gene_id: H340_12887
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: H340_12892
symbol: EMF00182.1
gene_biotype: protein_coding
description:
  Transferase; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.


ensembl_gene_id: H340_12902
symbol: EMF00184.1
gene_biotype: protein_coding
description:
  COG3321 Polyketide synthase modules and related proteins; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: H340_12937
symbol: pafA
gene_biotype: protein_coding
description:
  Proteasome accessory factor PafA; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.


ensembl_gene_id: H340_12972
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: H340_12977
symbol: tatC
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: H340_13012
symbol: EMF00095.1
gene_biotype: protein_coding
description:
  FAD-binding 9 siderophore-interacting domain-containing protein; COG2375 Siderophore-interacting protein.


ensembl_gene_id: H340_13037
symbol: EMF00100.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter/malic acid transport protein; COG1275 Tellurite resistance protein and related permeases.


ensembl_gene_id: H340_13097
symbol: EMF00112.1
gene_biotype: protein_coding
description:
  Aquaporin Z; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: H340_13107
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: H340_13117
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: H340_13122
symbol: EMF00117.1
gene_biotype: protein_coding
description:
  COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: H340_13132
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: H340_13137
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: H340_13142
symbol: EMF00121.1
gene_biotype: protein_coding
description:
  Magnesium or manganese-dependent protein phosphatase; COG2208 Serine phosphatase RsbU, regulator of sigma subunit.


ensembl_gene_id: H340_13152
symbol: EMF00123.1
gene_biotype: protein_coding
description:
  Nudix hydrolase family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: H340_13217
symbol: ybeY
gene_biotype: protein_coding
description:
  Metal-binding heat shock protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: H340_13232
symbol: EMF00039.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: H340_13242
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: H340_13247
symbol: EMF00042.1
gene_biotype: protein_coding
description:
  Putative Hit-family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: H340_13252
symbol: EMF00043.1
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: H340_13262
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: H340_13267
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: H340_13287
symbol: EMF00050.1
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: H340_13297
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: H340_13362
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: H340_13372
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: H340_13402
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: H340_13412
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: H340_13521
symbol: sdhB
gene_biotype: protein_coding
description:
  COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: H340_13571
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: H340_13576
symbol: EMF00011.1
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_13626
symbol: EMF00021.1
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: H340_13631
symbol: EMF00022.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: H340_13661
symbol: EMF00028.1
gene_biotype: protein_coding
description:
  Glycine betaine-binding lipoprotein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: H340_13666
symbol: EMF00029.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: H340_13906
symbol: fbpC
gene_biotype: protein_coding
description:
  ABC transporter; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H340_13916
symbol: EME99892.1
gene_biotype: protein_coding
description:
  Putative solute-binding transport system protein; COG4143 ABC-type thiamine transport system, periplasmic component.


ensembl_gene_id: H340_13921
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: H340_13931
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: H340_13941
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: H340_13956
symbol: EME99900.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: H340_13961
symbol: EME99901.1
gene_biotype: protein_coding
description:
  DNA protecting protein DprA; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: H340_13971
symbol: EME99903.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: H340_14006
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: H340_14011
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: H340_14016
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: H340_14036
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: H340_14046
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: H340_14051
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: H340_14076
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: H340_14081
symbol: EME99925.1
gene_biotype: protein_coding
description:
  Cytosine or purine or uracil or thiamine or allantoin permease family protein; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: H340_14106
symbol: EME99930.1
gene_biotype: protein_coding
description:
  Sugar transporter; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: H340_14111
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome associated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: H340_14216
symbol: EME99879.1
gene_biotype: protein_coding
description:
  COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family.


ensembl_gene_id: H340_14236
symbol: EME99883.1
gene_biotype: protein_coding
description:
  COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H340_14271
symbol: murQ
gene_biotype: protein_coding
description:
  N-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.


ensembl_gene_id: H340_14311
symbol: EME99821.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_14361
symbol: EME99831.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.


ensembl_gene_id: H340_14411
symbol: EME99841.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H340_14431
symbol: mqnD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.


ensembl_gene_id: H340_14436
symbol: mqnB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: H340_14521
symbol: EME99765.1
gene_biotype: protein_coding
description:
  UDP phosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: H340_14541
symbol: EME99769.1
gene_biotype: protein_coding
description:
  Periplasmic solute binding protein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: H340_14546
symbol: glyQS
gene_biotype: protein_coding
description:
  glycyl-tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: H340_14586
symbol: EME99778.1
gene_biotype: protein_coding
description:
  Riboflavin-specific deaminase domain-containing protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis.


ensembl_gene_id: H340_14681
symbol: EME99797.1
gene_biotype: protein_coding
description:
  Putative dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: H340_14686
symbol: EME99798.1
gene_biotype: protein_coding
description:
  Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: H340_14701
symbol: EME99801.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: H340_14706
symbol: EME99802.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: H340_14711
symbol: EME99803.1
gene_biotype: protein_coding
description:
  CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: H340_14726
symbol: EME99806.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_14746
symbol: EME99810.1
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: H340_14756
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: H340_14791
symbol: EME99727.1
gene_biotype: protein_coding
description:
  Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: H340_14796
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: H340_14801
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: H340_14826
symbol: hflX
gene_biotype: protein_coding
description:
  ATP/GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: H340_14851
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: H340_14871
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: H340_14891
symbol: EME99747.1
gene_biotype: protein_coding
description:
  Glutamate uptake system ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: H340_14896
symbol: EME99748.1
gene_biotype: protein_coding
description:
  Family 3 extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: H340_14931
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: H340_14986
symbol: EME99677.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H340_15031
symbol: EME99686.1
gene_biotype: protein_coding
description:
  Putative acyltransferase; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.


ensembl_gene_id: H340_15056
symbol: EME99691.1
gene_biotype: protein_coding
description:
  Peptidase C14 caspase catalytic subunit p20; COG4249 Uncharacterized protein containing caspase domain.


ensembl_gene_id: H340_15086
symbol: EME99697.1
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H340_15136
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: H340_15141
symbol: EME99708.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol/serine O-phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H340_15156
symbol: EME99711.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase.


ensembl_gene_id: H340_15266
symbol: EME99645.1
gene_biotype: protein_coding
description:
  Cobalamin B12-binding domain-containing protein; COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).


ensembl_gene_id: H340_15296
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: H340_15301
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: H340_15316
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: H340_15321
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: H340_15331
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: H340_15356
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: H340_15441
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: H340_15481
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: H340_15506
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: H340_15536
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: H340_15541
symbol: EME99615.1
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: H340_15556
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: H340_15561
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: H340_15586
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: H340_15601
symbol: EME99627.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_15641
symbol: EME99561.1
gene_biotype: protein_coding
description:
  Epsilon-poly-L-lysine synthase; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_15696
symbol: EME99572.1
gene_biotype: protein_coding
description:
  Alpha-methylacyl-CoA racemase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: H340_15706
symbol: EME99574.1
gene_biotype: protein_coding
description:
  5-methylcytosine methyltransferase; COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: H340_15716
symbol: EME99576.1
gene_biotype: protein_coding
description:
  DNA helicase; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; overlaps another CDS with the same product name.


ensembl_gene_id: H340_15721
symbol: EME99577.1
gene_biotype: protein_coding
description:
  DNA helicase; COG0210 Superfamily I DNA and RNA helicases; overlaps another CDS with the same product name.


ensembl_gene_id: H340_15751
symbol: EME99583.1
gene_biotype: protein_coding
description:
  COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: H340_15766
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: H340_15781
symbol: ppa-2
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: H340_15831
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: H340_15841
symbol: EME99522.1
gene_biotype: protein_coding
description:
  Putative cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: H340_15961
symbol: acpP-3
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: H340_15966
symbol: EME99547.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: H340_16011
symbol: EME99556.1
gene_biotype: protein_coding
description:
  Transcription factor; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_16016
symbol: EME99557.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase III; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: H340_16066
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: H340_16076
symbol: EME99486.1
gene_biotype: protein_coding
description:
  COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; Belongs to the UPF0309 family.


ensembl_gene_id: H340_16091
symbol: EME99489.1
gene_biotype: protein_coding
description:
  FAD-binding monooxygenase protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_16131
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: H340_16181
symbol: gabD2
gene_biotype: protein_coding
description:
  Succinic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: H340_16211
symbol: EME99439.1
gene_biotype: protein_coding
description:
  FMN-dependent monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_16241
symbol: mshC
gene_biotype: protein_coding
description:
  cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.


ensembl_gene_id: H340_16266
symbol: EME99450.1
gene_biotype: protein_coding
description:
  COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: H340_16306
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: H340_16311
symbol: EME99459.1
gene_biotype: protein_coding
description:
  COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: H340_16321
symbol: EME99461.1
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: H340_16331
symbol: EME99463.1
gene_biotype: protein_coding
description:
  Lipoprotein oligopeptide binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: H340_16356
symbol: EME99468.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.


ensembl_gene_id: H340_16371
symbol: arc
gene_biotype: protein_coding
description:
  ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.


ensembl_gene_id: H340_16381
symbol: pup
gene_biotype: protein_coding
description:
  Ubiquitin-like protein pup; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.


ensembl_gene_id: H340_16386
symbol: prcB
gene_biotype: protein_coding
description:
  20S proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.


ensembl_gene_id: H340_16391
symbol: prcA
gene_biotype: protein_coding
description:
  20S proteasome subunits A and B; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.


ensembl_gene_id: H340_16396
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: H340_16406
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: H340_16411
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: H340_16436
symbol: EME99404.1
gene_biotype: protein_coding
description:
  Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: H340_16441
symbol: EME99405.1
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: H340_16451
symbol: EME99407.1
gene_biotype: protein_coding
description:
  S-adenosyl-L-methionine: L-methionine S-methyltransferase; COG0500 SAM-dependent methyltransferases.


ensembl_gene_id: H340_16461
symbol: EME99409.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_16481
symbol: EME99413.1
gene_biotype: protein_coding
description:
  Thiotemplate mechanism natural product synthetase; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: H340_16491
symbol: clpP-2
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: H340_16526
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: H340_16531
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: H340_16536
symbol: bioD
gene_biotype: protein_coding
description:
  Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: H340_16621
symbol: glgE
gene_biotype: protein_coding
description:
  Alpha-amylase; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: H340_16636
symbol: glgB
gene_biotype: protein_coding
description:
  Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: H340_16646
symbol: EME99371.1
gene_biotype: protein_coding
description:
  ECF subfamily protein RNA polymerase sigma-24 subunit; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H340_16686
symbol: EME99379.1
gene_biotype: protein_coding
description:
  NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: H340_16711
symbol: EME99384.1
gene_biotype: protein_coding
description:
  Putative two-component system response regulator; COG4565 Response regulator of citrate/malate metabolism.


ensembl_gene_id: H340_16716
symbol: EME99385.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: H340_16761
symbol: EME99394.1
gene_biotype: protein_coding
description:
  Putative ABC transporter integral membrane protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: H340_16781
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: H340_16841
symbol: EME99327.1
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: H340_16876
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: H340_16901
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: H340_16911
symbol: nfo
gene_biotype: protein_coding
description:
  Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: H340_16926
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: H340_16936
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: H340_16941
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: H340_16946
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: H340_16956
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: H340_16966
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: H340_16971
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: H340_16976
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: H340_16986
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: H340_16991
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: H340_16996
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: H340_17001
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: H340_17006
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: H340_17011
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: H340_17016
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: H340_17021
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: H340_17086
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: H340_17156
symbol: EME99293.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: H340_17161
symbol: EME99294.1
gene_biotype: protein_coding
description:
  NAD-binding protein 6-phosphogluconate dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: H340_17181
symbol: EME99298.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2039 Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase).


ensembl_gene_id: H340_17191
symbol: EME99300.1
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance reductase B; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: H340_17246
symbol: EME99311.1
gene_biotype: protein_coding
description:
  Carbohydrate kinase; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family.


ensembl_gene_id: H340_17251
symbol: EME99312.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: H340_17267
symbol: mtnA
gene_biotype: protein_coding
description:
  Initiation factor eIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: H340_17292
symbol: hpf
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: H340_17312
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: H340_17342
symbol: EME99255.1
gene_biotype: protein_coding
description:
  Nucleotide phosphorylase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: H340_17347
symbol: EME99256.1
gene_biotype: protein_coding
description:
  Dolichyl-phosphate beta-D-mannosyltransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: H340_17392
symbol: EME99265.1
gene_biotype: protein_coding
description:
  Putative sugar ABC transporter solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: H340_17427
symbol: EME99211.1
gene_biotype: protein_coding
description:
  Anaerobic sulfite reductase subunit B; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: H340_17492
symbol: EME99224.1
gene_biotype: protein_coding
description:
  GCN5-like N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: H340_17512
symbol: EME99228.1
gene_biotype: protein_coding
description:
  Peptide-aspartate beta-dioxygenase; COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases.


ensembl_gene_id: H340_17522
symbol: EME99230.1
gene_biotype: protein_coding
description:
  Cytidyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: H340_17567
symbol: EME99170.1
gene_biotype: protein_coding
description:
  RpoD subfamily RNA polymerase sigma-70 subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: H340_17592
symbol: EME99175.1
gene_biotype: protein_coding
description:
  1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: H340_17597
symbol: EME99176.1
gene_biotype: protein_coding
description:
  COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); IIA component or PTS system, fructose-specific IIB component or PTS system,fructose-specific IIC component.


ensembl_gene_id: H340_17617
symbol: mscL
gene_biotype: protein_coding
description:
  Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: H340_17647
symbol: EME99186.1
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: H340_17657
symbol: EME99188.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: H340_17662
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: H340_17672
symbol: EME99191.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: H340_17712
symbol: EME99199.1
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: H340_17717
symbol: EME99200.1
gene_biotype: protein_coding
description:
  Transmembrane transport protein; COG0659 Sulfate permease and related transporters (MFS superfamily).


ensembl_gene_id: H340_17749
symbol: EME99128.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H340_17754
symbol: EME99129.1
gene_biotype: protein_coding
description:
  Mannose-1-phosphate guanyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: H340_17794
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: H340_17804
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: H340_17914
symbol: EME99161.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_17959
symbol: EME99095.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H340_17964
symbol: EME99096.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: H340_17969
symbol: EME99097.1
gene_biotype: protein_coding
description:
  ABC transporter solute-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: H340_18094
symbol: EME99122.1
gene_biotype: protein_coding
description:
  salicylyl-CoA 5-hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_18104
symbol: EME99124.1
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: H340_18139
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: H340_18149
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: H340_18274
symbol: rpsR
gene_biotype: protein_coding
description:
  SSU ribosomal protein S18p; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: H340_18299
symbol: rpsN-2
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: H340_18324
symbol: dcd
gene_biotype: protein_coding
description:
  Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.


ensembl_gene_id: H340_18336
symbol: rnj
gene_biotype: protein_coding
description:
  RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: H340_18341
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: H340_18356
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: H340_18361
symbol: EME99026.1
gene_biotype: protein_coding
description:
  Peptidase M16 domain-containing protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.


ensembl_gene_id: H340_18366
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: H340_18371
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: H340_18486
symbol: EME99051.1
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.


ensembl_gene_id: H340_18581
symbol: gvpA
gene_biotype: protein_coding
description:
  Gas vesicle synthesis-like protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.


ensembl_gene_id: H340_18596
symbol: EME98993.1
gene_biotype: protein_coding
description:
  Gas vesicle synthesis protein; Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth.


ensembl_gene_id: H340_18646
symbol: EME99003.1
gene_biotype: protein_coding
description:
  CsbD family protein; COG3237 Uncharacterized protein conserved in bacteria; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: H340_18746
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: H340_18776
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought  [...]


ensembl_gene_id: H340_18781
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: H340_18786
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: H340_18806
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: H340_18821
symbol: EME98953.1
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: H340_18906
symbol: EME98970.1
gene_biotype: protein_coding
description:
  Regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_19053
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: H340_19088
symbol: mca
gene_biotype: protein_coding
description:
  Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.


ensembl_gene_id: H340_19098
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: H340_19118
symbol: rbpA
gene_biotype: protein_coding
description:
  Electron transport protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: H340_19123
symbol: EME98872.1
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: H340_19128
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: H340_19148
symbol: whiA
gene_biotype: protein_coding
description:
  Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.


ensembl_gene_id: H340_19153
symbol: EME98878.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: H340_19163
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: H340_19183
symbol: EME98884.1
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) iron-sulfur domain-containing protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: H340_19188
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: H340_19213
symbol: EME98890.1
gene_biotype: protein_coding
description:
  Export associated protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: H340_19223
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: H340_19248
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: H340_19268
symbol: EME98901.1
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: H340_19288
symbol: EME98839.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_19313
symbol: sepF
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: H340_19378
symbol: EME98857.1
gene_biotype: protein_coding
description:
  COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: H340_19423
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.


ensembl_gene_id: H340_19453
symbol: EME98806.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; overlaps another CDS with the same product name; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: H340_19573
symbol: EME98830.1
gene_biotype: protein_coding
description:
  FtsW/RodA/SpoVE family cell cycle protein; COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.


ensembl_gene_id: H340_19598
symbol: EME98833.1
gene_biotype: protein_coding
description:
  Iron/ascorbate-dependent oxidoreductase; COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: H340_19613
symbol: EME98769.1
gene_biotype: protein_coding
description:
  Cysteine ABC transporter ATP-binding protein/permease; COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.


ensembl_gene_id: H340_19628
symbol: pat
gene_biotype: protein_coding
description:
  Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_19713
symbol: EME98789.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: H340_19723
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: H340_19778
symbol: EME98802.1
gene_biotype: protein_coding
description:
  FMN-binding pyridoxamine 5'-phosphate oxidase-like protein; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: H340_19838
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: H340_19848
symbol: EME98750.1
gene_biotype: protein_coding
description:
  Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: H340_19923
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: H340_19933
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: H340_19938
symbol: gatC
gene_biotype: protein_coding
description:
  asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: H340_19948
symbol: EME98716.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H340_19993
symbol: EME98725.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4591 ABC-type transport system, involved in lipoprotein release, permease component.


ensembl_gene_id: H340_20098
symbol: EME98693.1
gene_biotype: protein_coding
description:
  RNA-binding Sun protein; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: H340_20103
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: H340_20113
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: H340_20118
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: H340_20123
symbol: EME98698.1
gene_biotype: protein_coding
description:
  Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: H340_20128
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: H340_20143
symbol: pyrF
gene_biotype: protein_coding
description:
  COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: H340_20148
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: H340_20168
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: H340_20173
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: H340_20178
symbol: pyrR
gene_biotype: protein_coding
description:
  Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: H340_20188
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: H340_20193
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: H340_20208
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: H340_20218
symbol: EME98652.1
gene_biotype: protein_coding
description:
  Secreted tripeptidylaminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_20288
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: H340_20293
symbol: EME98667.1
gene_biotype: protein_coding
description:
  CobB/CobQ domain-containing protein glutamine amidotransferase; COG3442 Predicted glutamine amidotransferase.


ensembl_gene_id: H340_20393
symbol: ligB
gene_biotype: protein_coding
description:
  ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.


ensembl_gene_id: H340_20443
symbol: rbpA-2
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: H340_20458
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: H340_20518
symbol: EME98647.1
gene_biotype: protein_coding
description:
  Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: H340_20523
symbol: EME98648.1
gene_biotype: protein_coding
description:
  Transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H340_20588
symbol: EME98598.1
gene_biotype: protein_coding
description:
  Sensory box/GGDEF family protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: H340_20638
symbol: EME98608.1
gene_biotype: protein_coding
description:
  COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: H340_20653
symbol: EME98611.1
gene_biotype: protein_coding
description:
  N-acetyl-glucosamine catabolism protein; COG0647 Predicted sugar phosphatases of the HAD superfamily; Belongs to the HAD-like hydrolase superfamily.


ensembl_gene_id: H340_20704
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: H340_20719
symbol: EME98562.1
gene_biotype: protein_coding
description:
  Type II restriction-modification system DNA adenine-specific methylase; COG0286 Type I restriction-modification system methyltransferase subunit.


ensembl_gene_id: H340_20764
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: H340_20784
symbol: EME98575.1
gene_biotype: protein_coding
description:
  RelE/StbE family addiction module toxin; COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system.


ensembl_gene_id: H340_20809
symbol: EME98580.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: H340_20834
symbol: EME98585.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H340_20876
symbol: EME98538.1
gene_biotype: protein_coding
description:
  Sucraseferredoxin family protein; COG4759 Uncharacterized protein conserved in bacteria containing thioredoxin-like domain.


ensembl_gene_id: H340_20901
symbol: EME98543.1
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.


ensembl_gene_id: H340_20916
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: H340_20971
symbol: EME98557.1
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: H340_20991
symbol: EME98503.1
gene_biotype: protein_coding
description:
  Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: H340_21011
symbol: EME98507.1
gene_biotype: protein_coding
description:
  acyl-CoA carboxylase subunit beta; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).


ensembl_gene_id: H340_21041
symbol: EME98513.1
gene_biotype: protein_coding
description:
  GAF sensor-containing diguanylate cyclase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.


ensembl_gene_id: H340_21086
symbol: EME98522.1
gene_biotype: protein_coding
description:
  Helix-turn-helix domain-containing protein; COG1813 Predicted transcription factor, homolog of eukaryotic MBF1.


ensembl_gene_id: H340_21106
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: H340_21136
symbol: EME98463.1
gene_biotype: protein_coding
description:
  Putative ABC transporter; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H340_21186
symbol: EME98473.1
gene_biotype: protein_coding
description:
  FecCD-family membrane transport protein; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H340_21191
symbol: EME98474.1
gene_biotype: protein_coding
description:
  Iron ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: H340_21196
symbol: EME98475.1
gene_biotype: protein_coding
description:
  Iron transport lipoprotein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: H340_21206
symbol: EME98477.1
gene_biotype: protein_coding
description:
  Folate-dependent protein for Fe or S cluster synthesis or repair in oxidative stress; COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family.


ensembl_gene_id: H340_21211
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: H340_21256
symbol: EME98487.1
gene_biotype: protein_coding
description:
  EmrB/QacA family drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: H340_21301
symbol: EME98496.1
gene_biotype: protein_coding
description:
  NLP/P60-family secreted protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).


ensembl_gene_id: H340_21306
symbol: EME98497.1
gene_biotype: protein_coding
description:
  Putative high-affinity phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: H340_21311
symbol: EME98498.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: H340_21321
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: H340_21326
symbol: EME98435.1
gene_biotype: protein_coding
description:
  COG0587 DNA polymerase III, alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily.


ensembl_gene_id: H340_21391
symbol: EME98448.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: H340_21416
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: H340_21451
symbol: EME98460.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: H340_21456
symbol: EME98461.1
gene_biotype: protein_coding
description:
  ScpB-like chromosome partitioning protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: H340_21461
symbol: EME98462.1
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: H340_21501
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: H340_21506
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: H340_21511
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: H340_21521
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: H340_21551
symbol: EME98420.1
gene_biotype: protein_coding
description:
  Two-component regulator CutR; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H340_21561
symbol: EME98422.1
gene_biotype: protein_coding
description:
  Putative myo-inositol 1-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: H340_21566
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: H340_21606
symbol: EME98431.1
gene_biotype: protein_coding
description:
  Type I phosphodiesterase/nucleotide pyrophosphatase; COG1524 Uncharacterized proteins of the AP superfamily.


ensembl_gene_id: H340_21631
symbol: EME98375.1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: H340_21661
symbol: EME98381.1
gene_biotype: protein_coding
description:
  Glycogen debranching protein; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: H340_21711
symbol: EME98391.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: H340_21716
symbol: EME98392.1
gene_biotype: protein_coding
description:
  Putative ABC-type sulfate transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: H340_21721
symbol: EME98393.1
gene_biotype: protein_coding
description:
  Aliphatic sulfonate ABC transporter substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: H340_21726
symbol: EME98394.1
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: H340_21731
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: H340_21741
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: H340_21751
symbol: EME98399.1
gene_biotype: protein_coding
description:
  Putative nitrite/sulfite reductase; COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: H340_21766
symbol: rsgA-2
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: H340_21906
symbol: pfp
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: H340_21916
symbol: EME98370.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: H340_21926
symbol: EME98372.1
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: H340_21951
symbol: EME98316.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent Clp protease; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: H340_21991
symbol: EME98324.1
gene_biotype: protein_coding
description:
  SigE-like sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H340_22006
symbol: EME98327.1
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase-like FMN-binding protein; COG3787 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: H340_22016
symbol: disA
gene_biotype: protein_coding
description:
  DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.


ensembl_gene_id: H340_22021
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: H340_22211
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: H340_22216
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: H340_22241
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: H340_22246
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: H340_22256
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: H340_22311
symbol: EME98283.1
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: H340_22361
symbol: EME98245.1
gene_biotype: protein_coding
description:
  ABC-transporter transmembrane protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: H340_22431
symbol: EME98259.1
gene_biotype: protein_coding
description:
  long-chain-fatty-acid--CoA ligase; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_22446
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: H340_22516
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: H340_22521
symbol: EME98223.1
gene_biotype: protein_coding
description:
  Pyridoxal-phosphate-dependent aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: H340_22526
symbol: EME98224.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: H340_22546
symbol: EME98228.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_22556
symbol: EME98230.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: H340_22586
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: H340_22591
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: H340_22596
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: H340_22686
symbol: EME98191.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H340_22701
symbol: EME98194.1
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: H340_22721
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: H340_22726
symbol: EME98199.1
gene_biotype: protein_coding
description:
  SSS sodium solute transporter superfamily protein; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: H340_22736
symbol: EME98201.1
gene_biotype: protein_coding
description:
  Putative ssp-like protease; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: H340_22796
symbol: EME98154.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H340_22821
symbol: potA
gene_biotype: protein_coding
description:
  Polyamine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H340_22826
symbol: EME98160.1
gene_biotype: protein_coding
description:
  Polyamine ABC-transporter integral memb rane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: H340_22831
symbol: EME98161.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: H340_22851
symbol: EME98165.1
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_22876
symbol: EME98170.1
gene_biotype: protein_coding
description:
  Two-component system regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_22886
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: H340_22996
symbol: EME98139.1
gene_biotype: protein_coding
description:
  Oxidoreductase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: H340_23001
symbol: EME98140.1
gene_biotype: protein_coding
description:
  beta-ketoadipyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: H340_23021
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: H340_23086
symbol: EME98107.1
gene_biotype: protein_coding
description:
  Putative ABC transporter solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H340_23233
symbol: EME98082.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: H340_23243
symbol: EME98084.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_23308
symbol: EME98097.1
gene_biotype: protein_coding
description:
  Cysteine ABC transporter permease/ATP-binding protein CydD; COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.


ensembl_gene_id: H340_23403
symbol: EME98055.1
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: H340_23428
symbol: EME98060.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: H340_23433
symbol: EME98061.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: H340_23543
symbol: EME98026.1
gene_biotype: protein_coding
description:
  Secretory lipase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_23608
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: H340_23613
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: H340_23618
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: H340_23658
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: H340_23663
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: H340_23668
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: H340_23673
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu1; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: H340_23688
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: H340_23693
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: H340_23703
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: H340_23708
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: H340_23713
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: H340_23718
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: H340_23723
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: H340_23728
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: H340_23738
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: H340_23773
symbol: EME97963.1
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone (complex I) oxidoreductase; COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit.


ensembl_gene_id: H340_23858
symbol: EME97980.1
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: H340_23913
symbol: EME97939.1
gene_biotype: protein_coding
description:
  Cysteine dioxygenase type I; COG5553 Predicted metal-dependent enzyme of the double-stranded beta helix superfamily.


ensembl_gene_id: H340_23963
symbol: EME97949.1
gene_biotype: protein_coding
description:
  Aldehyde oxidase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: H340_23968
symbol: EME97950.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: H340_23993
symbol: EME97955.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: H340_23998
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: H340_24010
symbol: EME97904.1
gene_biotype: protein_coding
description:
  COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: H340_24065
symbol: rpsR-2
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: H340_24080
symbol: EME97918.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: H340_24130
symbol: EME97928.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, MerR family protein; COG0592 DNA polymerase sliding clamp subunit (PCNA homolog).


ensembl_gene_id: H340_24155
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: H340_24180
symbol: EME97885.1
gene_biotype: protein_coding
description:
  Xanthine dehydrogenase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: H340_24185
symbol: EME97886.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: H340_24260
symbol: EME97901.1
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: H340_24265
symbol: EME97902.1
gene_biotype: protein_coding
description:
  Ada metal-binding domain-containing protein; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.


ensembl_gene_id: H340_24280
symbol: EME97856.1
gene_biotype: protein_coding
description:
  Acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: H340_24285
symbol: EME97857.1
gene_biotype: protein_coding
description:
  LAO/AO transport system ATPase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: H340_24380
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: H340_24385
symbol: EME97877.1
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: H340_24430
symbol: ndk
gene_biotype: protein_coding
description:
  Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: H340_24480
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: H340_24490
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: H340_24495
symbol: EME97810.1
gene_biotype: protein_coding
description:
  2-hydroxy-3-oxopropionate reductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: H340_24540
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: H340_24550
symbol: EME97821.1
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: H340_24615
symbol: cynS
gene_biotype: protein_coding
description:
  Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: H340_24620
symbol: EME97784.1
gene_biotype: protein_coding
description:
  Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: H340_24665
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: H340_24680
symbol: EME97796.1
gene_biotype: protein_coding
description:
  COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_24690
symbol: EME97798.1
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: H340_24715
symbol: EME97803.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H340_24795
symbol: EME97763.1
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: H340_24800
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: H340_24815
symbol: EME97767.1
gene_biotype: protein_coding
description:
  Mov34/MPN/PAD-1 family protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.


ensembl_gene_id: H340_24840
symbol: EME97772.1
gene_biotype: protein_coding
description:
  PTS transmembrane protein; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.


ensembl_gene_id: H340_24850
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: H340_24860
symbol: EME97776.1
gene_biotype: protein_coding
description:
  dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: H340_24885
symbol: EME97781.1
gene_biotype: protein_coding
description:
  Putative 10kD chaperone subunit; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.


ensembl_gene_id: H340_24890
symbol: EME97782.1
gene_biotype: protein_coding
description:
  Quaternary ammonium compound-resistance protein sugE; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: H340_24897
symbol: EME97737.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: H340_24977
symbol: EME97753.1
gene_biotype: protein_coding
description:
  Peptidase S8 and S53 subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: H340_25007
symbol: EME97722.1
gene_biotype: protein_coding
description:
  Regulatory protein LuxR; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_25157
symbol: EME97710.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: H340_25202
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: H340_25212
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: H340_25227
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: H340_25232
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: H340_25257
symbol: nnrD
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: H340_25262
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: H340_25297
symbol: EME97692.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: H340_25332
symbol: EME97652.1
gene_biotype: protein_coding
description:
  Tylosin resistance ATP-binding protein tlrC; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: H340_25392
symbol: EME97664.1
gene_biotype: protein_coding
description:
  Class III aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_25457
symbol: EME97629.1
gene_biotype: protein_coding
description:
  Condensation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_25507
symbol: EME97639.1
gene_biotype: protein_coding
description:
  NAD-dependent epimerase/dehydratase; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: H340_25522
symbol: EME97642.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H340_25527
symbol: EME97643.1
gene_biotype: protein_coding
description:
  3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; COG2030 Acyl dehydratase.


ensembl_gene_id: H340_25532
symbol: fcl
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: H340_25567
symbol: EME97621.1
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase.


ensembl_gene_id: H340_25597
symbol: EME97592.1
gene_biotype: protein_coding
description:
  OpcA, an allosteric effector of glucose-6-phosphate dehydrogenase, actinobacterial; COG3429 Glucose-6-P dehydrogenase subunit.


ensembl_gene_id: H340_25602
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: H340_25612
symbol: EME97595.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: H340_25617
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: H340_25647
symbol: EME97602.1
gene_biotype: protein_coding
description:
  Iron-regulated ABC-type transporter; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: H340_25652
symbol: EME97603.1
gene_biotype: protein_coding
description:
  FeS assembly protein SufD; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: H340_25657
symbol: EME97604.1
gene_biotype: protein_coding
description:
  Ferredoxin, 2Fe-2S; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: H340_25667
symbol: EME97606.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H340_25707
symbol: EME97614.1
gene_biotype: protein_coding
description:
  Putative peptidase, subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: H340_25737
symbol: EME97576.1
gene_biotype: protein_coding
description:
  Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: H340_25752
symbol: EME97579.1
gene_biotype: protein_coding
description:
  malonyl-CoA-[acyl-carrier-protein] transacylase; COG0331 (acyl-carrier-protein) S-malonyltransferase.


ensembl_gene_id: H340_25777
symbol: EME97584.1
gene_biotype: protein_coding
description:
  Glutamate mutase S-subunit; COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).


ensembl_gene_id: H340_25812
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: H340_25827
symbol: EME97560.1
gene_biotype: protein_coding
description:
  Integral membrane transferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H340_25852
symbol: EME97565.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: H340_25877
symbol: EME97570.1
gene_biotype: protein_coding
description:
  Polyprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: H340_25962
symbol: EME97541.1
gene_biotype: protein_coding
description:
  Putative small neutral protease regulatory protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H340_26039
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: H340_26054
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division transporter, ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: H340_26059
symbol: EME97519.1
gene_biotype: protein_coding
description:
  Cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: H340_26069
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: H340_26104
symbol: EME97528.1
gene_biotype: protein_coding
description:
  DNA-binding protein HU 1; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: H340_26109
symbol: EME97499.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-dependent sugar phosphotransferase; COG2190 Phosphotransferase system IIA components.


ensembl_gene_id: H340_26114
symbol: EME97500.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: H340_26129
symbol: EME97503.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase; COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: H340_26249
symbol: def-3
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: H340_26279
symbol: EME97497.1
gene_biotype: protein_coding
description:
  GHMP kinase; COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase.


ensembl_gene_id: H340_26374
symbol: EME97440.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase family protein; COG3979 Uncharacterized protein contain chitin-binding domain type 3.


ensembl_gene_id: H340_26414
symbol: nucS
gene_biotype: protein_coding
description:
  Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.


ensembl_gene_id: H340_26424
symbol: EME97450.1
gene_biotype: protein_coding
description:
  Aldehyde monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_26474
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: H340_26621
symbol: EME97408.1
gene_biotype: protein_coding
description:
  2-oxoacid dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: H340_26636
symbol: EME97411.1
gene_biotype: protein_coding
description:
  Putative RNA polymerase ECF subfamily sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H340_26716
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: H340_26726
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: H340_26731
symbol: ribBA
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: H340_26746
symbol: EME97382.1
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: H340_26811
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: H340_26816
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: H340_26871
symbol: EME97369.1
gene_biotype: protein_coding
description:
  N-formimino-L-glutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: H340_26876
symbol: EME97370.1
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: H340_26911
symbol: EME97346.1
gene_biotype: protein_coding
description:
  Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1; COG1316 Transcriptional regulator.


ensembl_gene_id: H340_26921
symbol: EME97348.1
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; COG5479 Uncharacterized protein potentially involved in peptidoglycan biosynthesis.


ensembl_gene_id: H340_26936
symbol: fbiB
gene_biotype: protein_coding
description:
  F420-0-gamma-glutamyl ligase; Bifunctional enzyme that catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2- dependent reduction of dehydro-F420-0 to form F420-0.


ensembl_gene_id: H340_26941
symbol: fbiA
gene_biotype: protein_coding
description:
  LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.


ensembl_gene_id: H340_26946
symbol: EME97353.1
gene_biotype: protein_coding
description:
  Cysteine dioxygenase type I; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: H340_26951
symbol: whiB-6
gene_biotype: protein_coding
description:
  WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: H340_26991
symbol: EME97328.1
gene_biotype: protein_coding
description:
  2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase.


ensembl_gene_id: H340_27061
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: H340_27066
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: H340_27071
symbol: EME97313.1
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: H340_27106
symbol: EME97320.1
gene_biotype: protein_coding
description:
  Penicillin binding protein PbpA; COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.


ensembl_gene_id: H340_27180
symbol: EME97308.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: H340_27240
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: H340_27245
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: H340_27255
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: H340_27267
symbol: EME97271.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: H340_27282
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: H340_27292
symbol: EME97276.1
gene_biotype: protein_coding
description:
  Putative cell wall biosynthesis protein; COG0768 Cell division protein FtsI/penicillin-binding protein 2.


ensembl_gene_id: H340_27297
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: H340_27302
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: H340_27307
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: H340_27312
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: H340_27322
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: H340_27337
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: H340_27342
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: H340_27427
symbol: EME97248.1
gene_biotype: protein_coding
description:
  Iron-siderophore uptake system transmembrane component; COG4779 ABC-type enterobactin transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H340_27432
symbol: EME97249.1
gene_biotype: protein_coding
description:
  Iron-siderophore uptake system ATP-binding component; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: H340_27452
symbol: ppnK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: H340_27462
symbol: EME97255.1
gene_biotype: protein_coding
description:
  Putative recombination and DNA repair protein; May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: H340_27519
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: H340_27539
symbol: EME97218.1
gene_biotype: protein_coding
description:
  Oxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H340_27569
symbol: EME97224.1
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_27634
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: H340_27669
symbol: clpP-3
gene_biotype: protein_coding
description:
  Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: H340_27721
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: H340_27736
symbol: EME97176.1
gene_biotype: protein_coding
description:
  Endonuclease VIII and DNA N-glycosylase with an AP lyase activity; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.


ensembl_gene_id: H340_27761
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: H340_27766
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: H340_27776
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: H340_27796
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: H340_27820
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: H340_27825
symbol: EME97169.1
gene_biotype: protein_coding
description:
  Oxidoreductase alpha (molybdopterin) subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: H340_27830
symbol: EME97170.1
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: H340_27835
symbol: EME97171.1
gene_biotype: protein_coding
description:
  Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: H340_27840
symbol: EME97172.1
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H340_27845
symbol: EME97173.1
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H340_28015
symbol: proS-2
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyla [...]


ensembl_gene_id: H340_28035
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: H340_28040
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: H340_28045
symbol: EME97130.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.


ensembl_gene_id: H340_28055
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: H340_28065
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: H340_28070
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: H340_28075
symbol: EME97136.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: H340_28085
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: H340_28090
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: H340_28095
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: H340_28100
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: H340_28105
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: H340_28115
symbol: atpE
gene_biotype: protein_coding
description:
  F-type proton-transporting ATPase c chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: H340_28120
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: H340_28130
symbol: EME97114.1
gene_biotype: protein_coding
description:
  Transferase; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: H340_28140
symbol: EME97116.1
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: H340_28145
symbol: EME97117.1
gene_biotype: protein_coding
description:
  Sua5/YciO/YrdC/YwlC family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.


ensembl_gene_id: H340_28150
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: H340_28155
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: H340_28170
symbol: EME97094.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: H340_28175
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: H340_28180
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: H340_28200
symbol: rsmI
gene_biotype: protein_coding
description:
  Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: H340_28245
symbol: EME97084.1
gene_biotype: protein_coding
description:
  Putative stress-inducible protein; COG0589 Universal stress protein UspA and related nucleotide-binding proteins.


ensembl_gene_id: H340_28265
symbol: EME97088.1
gene_biotype: protein_coding
description:
  Oxidoreductase; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: H340_28315
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: H340_28335
symbol: tam
gene_biotype: protein_coding
description:
  Trans-aconitate 2-methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.


ensembl_gene_id: H340_28355
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: H340_28365
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: H340_28370
symbol: EME97055.1
gene_biotype: protein_coding
description:
  PTS system mannose-specific transporter subunits IIBCA; COG1445 Phosphotransferase system fructose-specific component IIB.


ensembl_gene_id: H340_28425
symbol: serC-2
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: H340_28520
symbol: EME97023.1
gene_biotype: protein_coding
description:
  Cellobiose ABC transporter permease protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: H340_28530
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: H340_28535
symbol: EME97026.1
gene_biotype: protein_coding
description:
  A-factor-responsive transcriptional activator; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: H340_28707
symbol: EME96988.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: H340_28737
symbol: EME96994.1
gene_biotype: protein_coding
description:
  Transport permease; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H340_28742
symbol: EME96995.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_28747
symbol: EME96996.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase.


ensembl_gene_id: H340_28777
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: H340_28782
symbol: EME96980.1
gene_biotype: protein_coding
description:
  Methionine--tRNA ligase; COG0143 Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: H340_28867
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase).


ensembl_gene_id: H340_28872
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: H340_29089
symbol: EME96915.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_29094
symbol: EME96916.1
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: H340_29099
symbol: EME96917.1
gene_biotype: protein_coding
description:
  Mandalate racemase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: H340_29114
symbol: EME96920.1
gene_biotype: protein_coding
description:
  Integral membrane sensor protein; COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism.


ensembl_gene_id: H340_29124
symbol: EME96900.1
gene_biotype: protein_coding
description:
  Transcriptional activator FtrA; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: H340_29164
symbol: EME96908.1
gene_biotype: protein_coding
description:
  WD40 domain-containing protein; COG0823 Periplasmic component of the Tol biopolymer transport system.


ensembl_gene_id: H340_29174
symbol: EME96910.1
gene_biotype: protein_coding
description:
  Thioester reductase domain protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: H340_29204
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: H340_29209
symbol: EME96895.1
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: H340_29234
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: H340_29269
symbol: EME96886.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.


ensembl_gene_id: H340_29284
symbol: EME96889.1
gene_biotype: protein_coding
description:
  Pyridoxal-phosphate-dependent aminotransferase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: H340_29299
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: H340_29309
symbol: EME96868.1
gene_biotype: protein_coding
description:
  Putative Dyp-type peroxidase family protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: H340_29314
symbol: EME96869.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC.


ensembl_gene_id: H340_29324
symbol: EME96871.1
gene_biotype: protein_coding
description:
  COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: H340_29344
symbol: EME96875.1
gene_biotype: protein_coding
description:
  COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: H340_29369
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: H340_29389
symbol: EME96858.1
gene_biotype: protein_coding
description:
  Glucosyl-3-phosphoglycerate synthase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: H340_29414
symbol: EME96863.1
gene_biotype: protein_coding
description:
  Family 1 extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: H340_29479
symbol: EME96837.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: H340_29554
symbol: EME96833.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: H340_29569
symbol: ku
gene_biotype: protein_coding
description:
  Hypothetical protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: H340_29791
symbol: ispG-5
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: H340_29811
symbol: EME96766.1
gene_biotype: protein_coding
description:
  Putative sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H340_29821
symbol: EME96768.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_29826
symbol: EME96769.1
gene_biotype: protein_coding
description:
  BldKD putative oligopeptide ABC transporter subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H340_29831
symbol: EME96770.1
gene_biotype: protein_coding
description:
  BldKC, ABC transporter integral membrane protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H340_29846
symbol: EME96773.1
gene_biotype: protein_coding
description:
  Peptidase S9B dipeptidylpeptidase IV domain-containing protein; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.


ensembl_gene_id: H340_29856
symbol: EME96775.1
gene_biotype: protein_coding
description:
  Putative N-acetyl-1-D-myo-inosityl-2-amino-2- deoxy-alpha-D-glucopyranoside deacetylase; COG2120 Uncharacterized proteins, LmbE homologs; Belongs to the MshB deacetylase family.


ensembl_gene_id: H340_29871
symbol: EME96756.1
gene_biotype: protein_coding
description:
  Sugar kinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: H340_29906
symbol: EME96763.1
gene_biotype: protein_coding
description:
  Nitrilotriacetate monooxygenase component B; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H340_29996
symbol: EME96743.1
gene_biotype: protein_coding
description:
  COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: H340_30011
symbol: EME96729.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: H340_30036
symbol: EME96734.1
gene_biotype: protein_coding
description:
  Putative anti-sigma regulatory factor, serine/threonine protein kinase; COG3920 Signal transduction histidine kinase.


ensembl_gene_id: H340_30171
symbol: EME96707.1
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis.


ensembl_gene_id: H340_30198
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: H340_30228
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: H340_30248
symbol: EME96684.1
gene_biotype: protein_coding
description:
  Sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: H340_30258
symbol: EME96686.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: H340_30263
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: H340_30278
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.


ensembl_gene_id: H340_30293
symbol: EME96674.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes.


ensembl_gene_id: H340_30358
symbol: EME96665.1
gene_biotype: protein_coding
description:
  COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: H340_30373
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: H340_30498
symbol: EME96634.1
gene_biotype: protein_coding
description:
  Putative NAD dependent epimerase/dehydratase family protein; COG1090 Predicted nucleoside-diphosphate sugar epimerase.


ensembl_gene_id: H340_30513
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: H340_30518
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: H340_30543
symbol: EME96623.1
gene_biotype: protein_coding
description:
  ECF family sigma-70 type sigma factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.


ensembl_gene_id: H340_30573
symbol: EME96629.1
gene_biotype: protein_coding
description:
  Ab hydrolase, alpha/beta hydrolase fold protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H340_30588
symbol: EME96612.1
gene_biotype: protein_coding
description:
  NAD-binding D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: H340_30728
symbol: EME96586.1
gene_biotype: protein_coding
description:
  Oxidoreductase, zinc-containing alcohol dehydrogenase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H340_30793
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: H340_30808
symbol: EME96582.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H340_30823
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: H340_30833
symbol: priA-2
gene_biotype: protein_coding
description:
  Phosphoribosyl isomerase A; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family.


ensembl_gene_id: H340_30838
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: H340_30853
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: H340_30858
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: H340_30868
symbol: EME96572.1
gene_biotype: protein_coding
description:
  Peptidase S16 lon domain-containing protein; COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease.


ensembl_gene_id: H340_30883
symbol: EME96554.1
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: H340_30968
symbol: EME96546.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: H340_31093
symbol: pxpA
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: H340_31118
symbol: EME96507.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA.


ensembl_gene_id: H340_31243
symbol: rimO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: H340_31248
symbol: EME96488.1
gene_biotype: protein_coding
description:
  COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H340_31253
symbol: EME96489.1
gene_biotype: protein_coding
description:
  Protein Implicated in DNA repair function with RecA and MutS; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: H340_31303
symbol: EME96483.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: H340_31318
symbol: whiB-7
gene_biotype: protein_coding
description:
  Putative WhiB family regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: H340_31323
symbol: EME96471.1
gene_biotype: protein_coding
description:
  DNA-binding response regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H340_31333
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: H340_31378
symbol: EME96468.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: H340_31398
symbol: EME96458.1
gene_biotype: protein_coding
description:
  ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: H340_31408
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: H340_31493
symbol: pepA
gene_biotype: protein_coding
description:
  Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: H340_31498
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: H340_31563
symbol: sepF-3
gene_biotype: protein_coding
description:
  Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: H340_31568
symbol: EME96424.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: H340_31578
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: H340_31720
symbol: EME96398.1
gene_biotype: protein_coding
description:
  Zinc-binding oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H340_31760
symbol: EME96384.1
gene_biotype: protein_coding
description:
  Putative cobalt transporter; COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters.


ensembl_gene_id: H340_31790
symbol: mqnC
gene_biotype: protein_coding
description:
  Hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: H340_31805
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: H340_31825
symbol: EME96373.1
gene_biotype: protein_coding
description:
  Rif11-like protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H340_31845
symbol: EME96366.1
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: H340_31850
symbol: EME96367.1
gene_biotype: protein_coding
description:
  Putative maltose ABC transporter permease; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: H340_31865
symbol: EME96361.1
gene_biotype: protein_coding
description:
  COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: H340_31965
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: H340_31975
symbol: EME96339.1
gene_biotype: protein_coding
description:
  Mrr restriction system protein; COG2310 Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1.


ensembl_gene_id: H340_32020
symbol: EME96334.1
gene_biotype: protein_coding
description:
  Phospholipase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: H340_32135
symbol: EME96309.1
gene_biotype: protein_coding
description:
  iron(III) dicitrate transport permease; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: H340_32160
symbol: EME96308.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase).


ensembl_gene_id: H340_32175
symbol: dapD
gene_biotype: protein_coding
description:
  Transferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: H340_32185
symbol: EME96301.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: H340_32210
symbol: EME96298.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4152 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: H340_32260
symbol: EME96286.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: H340_32287
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


