# geneInfo

ensembl_gene_id: BN779_00002
symbol: hldE
gene_biotype: protein_coding
description:
  Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: BN779_00010
symbol: murA
gene_biotype: protein_coding
description:
  uDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: BN779_00011
symbol: metAA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: BN779_00016
symbol: CCX91468.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BN779_00022
symbol: cca
gene_biotype: protein_coding
description:
  Multifunctional CCA protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: BN779_00023
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: BN779_00024
symbol: CCX91480.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00026
symbol: tsaD
gene_biotype: protein_coding
description:
  Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: BN779_00027
symbol: dtd
gene_biotype: protein_coding
description:
  d-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: BN779_00028
symbol: crcB
gene_biotype: protein_coding
description:
  Protein CrcB homolog; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: BN779_00029
symbol: rpsU
gene_biotype: protein_coding
description:
  30S ribosomal protein S21; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: BN779_00033
symbol: CCX91502.1
gene_biotype: protein_coding
description:
  Phosphoglycerate dehydrogenase and related dehydrogenases; Product inferred by homology to UniProt; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: BN779_00044
symbol: CCX92217.1
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: BN779_00046
symbol: sstT
gene_biotype: protein_coding
description:
  Serine/threonine transporter SstT 1; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BN779_00062
symbol: CCX92536.1
gene_biotype: protein_coding
description:
  Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate.


ensembl_gene_id: BN779_00063
symbol: CCX92537.1
gene_biotype: protein_coding
description:
  Galactokinase; Product inferred by homology to UniProt; Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: BN779_00065
symbol: CCX92540.1
gene_biotype: protein_coding
description:
  uDP-glucose 4-epimerase; Product inferred by homology to UniProt; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: BN779_00067
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: BN779_00069
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: BN779_00077
symbol: rpoD
gene_biotype: protein_coding
description:
  rNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: BN779_00078
symbol: CCX92559.1
gene_biotype: protein_coding
description:
  Probable transcriptional regulatory protein HMPREF9444_01377; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00079
symbol: aspS
gene_biotype: protein_coding
description:
  aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: BN779_00080
symbol: CCX92562.1
gene_biotype: protein_coding
description:
  Putative glutamine ABC transporter periplasmic glutamine-binding protein GlnH; Product inferred by homology to UniProt; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: BN779_00081
symbol: CCX92563.1
gene_biotype: protein_coding
description:
  Putative glutamine ABC transporter periplasmic glutamine-binding protein GlnH; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00085
symbol: CCX92808.1
gene_biotype: protein_coding
description:
  Transporter; Product inferred by homology to UniProt; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: BN779_00088
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: BN779_00089
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: BN779_00092
symbol: CCX92818.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter permease protein; Product inferred by homology to UniProt; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: BN779_00095
symbol: CCX92824.1
gene_biotype: protein_coding
description:
  Sel1 repeat-containing domain protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.


ensembl_gene_id: BN779_00104
symbol: CCX93209.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.


ensembl_gene_id: BN779_00105
symbol: cas2
gene_biotype: protein_coding
description:
  cRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: BN779_00106
symbol: cas1
gene_biotype: protein_coding
description:
  cRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: BN779_00109
symbol: CCX93215.1
gene_biotype: protein_coding
description:
  5-formyltetrahydrofolate cyclo-ligase; Product inferred by homology to UniProt; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: BN779_00110
symbol: CCX93216.1
gene_biotype: protein_coding
description:
  Preprotein translocase SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: BN779_00111
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: BN779_00113
symbol: ftsH
gene_biotype: protein_coding
description:
  aTP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: BN779_00114
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: BN779_00117
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA 2; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: BN779_00118
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: BN779_00120
symbol: grpE
gene_biotype: protein_coding
description:
  Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: BN779_00121
symbol: bamE
gene_biotype: protein_coding
description:
  smpA / OmlA family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BN779_00123
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: BN779_00137
symbol: CCX90040.1
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00140
symbol: CCX90047.1
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: BN779_00146
symbol: CCX90630.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; Product inferred by homology to UniProt; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BN779_00148
symbol: CCX90633.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: BN779_00163
symbol: CCX90824.1
gene_biotype: protein_coding
description:
  Putative arginine ABC transporter periplasmic arginine-binding protein ArtJ; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00167
symbol: CCX90828.1
gene_biotype: protein_coding
description:
  Maltose/maltodextrin import ATP-binding protein MalK; Product inferred by homology to UniProt; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BN779_00170
symbol: CCX90831.1
gene_biotype: protein_coding
description:
  Maltose-binding periplasmic protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BN779_00172
symbol: CCX90836.1
gene_biotype: protein_coding
description:
  Putative YbaK/EbsC protein; Product inferred by homology to UniProt; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: BN779_00178
symbol: CCX90845.1
gene_biotype: protein_coding
description:
  Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: BN779_00204
symbol: CCX90884.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00206
symbol: CCX90887.1
gene_biotype: protein_coding
description:
  aBC transporter component; Product inferred by homology to UniProt; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BN779_00212
symbol: CCX90897.1
gene_biotype: protein_coding
description:
  Aminotransferase; Product inferred by homology to UniProt; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BN779_00213
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: BN779_00215
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: BN779_00216
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: BN779_00225
symbol: nnrE
gene_biotype: protein_coding
description:
  yjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]


ensembl_gene_id: BN779_00228
symbol: mutL
gene_biotype: protein_coding
description:
  dNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: BN779_00229
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: BN779_00230
symbol: CCX90918.1
gene_biotype: protein_coding
description:
  Carboxylesterase; Product inferred by homology to UniProt; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: BN779_00235
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthase; Product inferred by homology to UniProt; Belongs to the SAICAR synthetase family.


ensembl_gene_id: BN779_00248
symbol: cas1-2
gene_biotype: protein_coding
description:
  cRISPR-associated endonuclease Cas1 2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: BN779_00249
symbol: cas2-2
gene_biotype: protein_coding
description:
  cRISPR-associated endoribonuclease Cas2 2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: BN779_00258
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC 2; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: BN779_00260
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: BN779_00261
symbol: CCX90985.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: BN779_00262
symbol: yacG
gene_biotype: protein_coding
description:
  dNA gyrase inhibitor YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: BN779_00263
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: BN779_00264
symbol: surA
gene_biotype: protein_coding
description:
  Chaperone SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: BN779_00265
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase 1; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: BN779_00266
symbol: rsmA
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: BN779_00268
symbol: CCX90996.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: BN779_00269
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase 1; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: BN779_00273
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: BN779_00274
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: BN779_00278
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: BN779_00279
symbol: CCX91035.1
gene_biotype: protein_coding
description:
  Homoserine dehydrogenase; Product inferred by homology to UniProt; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: BN779_00283
symbol: CCX91076.1
gene_biotype: protein_coding
description:
  Efflux transporter RND family MFP subunit; Product inferred by homology to UniProt; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: BN779_00284
symbol: macB
gene_biotype: protein_coding
description:
  Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: BN779_00285
symbol: CCX91078.1
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: BN779_00286
symbol: CCX91079.1
gene_biotype: protein_coding
description:
  Efflux transporter outer membrane factor lipoprotein NodT family; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00288
symbol: CCX91081.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: BN779_00289
symbol: CCX91082.1
gene_biotype: protein_coding
description:
  Phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: BN779_00292
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: BN779_00293
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: BN779_00294
symbol: trpF
gene_biotype: protein_coding
description:
  Indole-3-glycerol phosphate synthase; Product inferred by homology to UniProt; Belongs to the TrpF family.


ensembl_gene_id: BN779_00295
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: BN779_00308
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: BN779_00315
symbol: CCX91117.1
gene_biotype: protein_coding
description:
  Cellulose synthase (UDP-forming); Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.


ensembl_gene_id: BN779_00316
symbol: CCX91120.1
gene_biotype: protein_coding
description:
  Cellulose synthase subunit B; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: BN779_00321
symbol: cas1-3
gene_biotype: protein_coding
description:
  cRISPR-associated endonuclease Cas1 1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: BN779_00329
symbol: CCX91149.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the Nudix hydrolase family.


ensembl_gene_id: BN779_00335
symbol: CCX91166.1
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: BN779_00336
symbol: pstB
gene_biotype: protein_coding
description:
  aBC-type phosphate transport system ATPase component; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: BN779_00338
symbol: CCX91170.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BN779_00347
symbol: CCX91183.1
gene_biotype: protein_coding
description:
  Intracellular maltogenic amylase; Product inferred by homology to UniProt; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BN779_00349
symbol: gltX
gene_biotype: protein_coding
description:
  glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: BN779_00357
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: BN779_00368
symbol: CCX91226.1
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase/aspartoacylase family protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00370
symbol: CCX91230.1
gene_biotype: protein_coding
description:
  Hypothetical flagellar protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: BN779_00371
symbol: CCX91231.1
gene_biotype: protein_coding
description:
  fliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: BN779_00372
symbol: CCX91232.1
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: BN779_00374
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: BN779_00375
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: BN779_00376
symbol: CCX91238.1
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein fliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: BN779_00381
symbol: CCX91251.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: BN779_00387
symbol: CCX91276.1
gene_biotype: protein_coding
description:
  Sulfur transfer protein SirA; Product inferred by homology to UniProt; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: BN779_00388
symbol: mutM
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: BN779_00389
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: BN779_00391
symbol: kdkA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: BN779_00393
symbol: CCX91288.1
gene_biotype: protein_coding
description:
  Putative 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: BN779_00395
symbol: hldD
gene_biotype: protein_coding
description:
  aDP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: BN779_00397
symbol: gpmI
gene_biotype: protein_coding
description:
  2 3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: BN779_00399
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: BN779_00400
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Product inferred by homology to UniProt; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: BN779_00401
symbol: nfuA
gene_biotype: protein_coding
description:
  fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: BN779_00402
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: BN779_00403
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA 1; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: BN779_00406
symbol: ribB
gene_biotype: protein_coding
description:
  3 4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: BN779_00407
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: BN779_00408
symbol: rbsK
gene_biotype: protein_coding
description:
  Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: BN779_00411
symbol: CCX91319.1
gene_biotype: protein_coding
description:
  Periplasmic binding protein and sugar binding domain of the LacI family protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00414
symbol: CCX91327.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: BN779_00415
symbol: CCX91329.1
gene_biotype: protein_coding
description:
  Putative glucose-specific phosphotransferase enzyme IIA component; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00419
symbol: CCX91336.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the FGGY kinase family.


ensembl_gene_id: BN779_00428
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase; Product inferred by homology to UniProt; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: BN779_00430
symbol: CCX91358.1
gene_biotype: protein_coding
description:
  Nitrogen regulatory protein PII; Product inferred by homology to UniProt; Belongs to the P(II) protein family.


ensembl_gene_id: BN779_00431
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: BN779_00432
symbol: CCX91364.1
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: BN779_00433
symbol: rpmB
gene_biotype: protein_coding
description:
  50S ribosomal protein L28; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: BN779_00434
symbol: rpmG
gene_biotype: protein_coding
description:
  50S ribosomal protein L33; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: BN779_00437
symbol: CCX91375.1
gene_biotype: protein_coding
description:
  Guanosine 3' 5'-bis(Diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: BN779_00438
symbol: rpoZ
gene_biotype: protein_coding
description:
  dNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: BN779_00440
symbol: engB
gene_biotype: protein_coding
description:
  Probable GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: BN779_00451
symbol: CCX91399.1
gene_biotype: protein_coding
description:
  Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: BN779_00454
symbol: CCX91408.1
gene_biotype: protein_coding
description:
  Putative Trk system potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: BN779_00455
symbol: CCX91409.1
gene_biotype: protein_coding
description:
  Putative potassium transporter peripheral membrane component; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00456
symbol: CCX91411.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: BN779_00457
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: BN779_00458
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: BN779_00460
symbol: purE
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: BN779_00461
symbol: CCX91418.1
gene_biotype: protein_coding
description:
  tRNA threonylcarbamoyladenosine biosynthesis protein RimN; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: BN779_00462
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: BN779_00463
symbol: rsmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase J; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: BN779_00464
symbol: CCX91422.1
gene_biotype: protein_coding
description:
  Molybdate ABC transporter periplasmic molybdate-binding protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00465
symbol: CCX91423.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00466
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: BN779_00467
symbol: glmU
gene_biotype: protein_coding
description:
  Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: BN779_00468
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase 1; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: BN779_00470
symbol: CCX91428.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: BN779_00473
symbol: CCX91431.1
gene_biotype: protein_coding
description:
  Putative HTH-type transcriptional activator IlvY; Product inferred by homology to UniProt; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BN779_00474
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: BN779_00487
symbol: CCX91454.1
gene_biotype: protein_coding
description:
  Alkaline phosphatase H; Product inferred by homology to UniProt; Belongs to the alkaline phosphatase family.


ensembl_gene_id: BN779_00489
symbol: CCX91516.1
gene_biotype: protein_coding
description:
  Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: BN779_00492
symbol: CCX91519.1
gene_biotype: protein_coding
description:
  Acriflavine resistance protein A; Product inferred by homology to UniProt; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: BN779_00498
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BN779_00499
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase; Product inferred by homology to UniProt; Belongs to the IlvD/Edd family.


ensembl_gene_id: BN779_00500
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine ammonia-lyase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: BN779_00506
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: BN779_00507
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: BN779_00508
symbol: xerC-2
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC 1; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: BN779_00512
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: BN779_00513
symbol: CCX91549.1
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate reductase; Product inferred by homology to UniProt; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: BN779_00516
symbol: CCX91568.1
gene_biotype: protein_coding
description:
  Sodium/glucose cotransporter; Product inferred by homology to UniProt; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: BN779_00517
symbol: CCX91569.1
gene_biotype: protein_coding
description:
  Putative ATP synthase F0 A subunit; Product inferred by homology to UniProt; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: BN779_00520
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: BN779_00530
symbol: CCX91586.1
gene_biotype: protein_coding
description:
  sua5/YciO/YrdC/YwlC family protein; Product inferred by homology to UniProt; Belongs to the SUA5 family.


ensembl_gene_id: BN779_00532
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: BN779_00533
symbol: CCX91591.1
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: BN779_00537
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: BN779_00541
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: BN779_00542
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: BN779_00544
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: BN779_00548
symbol: CCX91618.1
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: BN779_00549
symbol: CCX91619.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: BN779_00551
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: BN779_00553
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: BN779_00555
symbol: CCX91628.1
gene_biotype: protein_coding
description:
  Cysteine synthase; Product inferred by homology to UniProt; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: BN779_00556
symbol: CCX91630.1
gene_biotype: protein_coding
description:
  Transporter dicarboxylate/amino acid:cation Na+/H+ symporter family protein; Product inferred by homology to UniProt; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BN779_00561
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: BN779_00562
symbol: CCX91638.1
gene_biotype: protein_coding
description:
  Nucleoid-associated protein HMPREF9444_02080; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: BN779_00565
symbol: CCX91643.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: BN779_00567
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: BN779_00571
symbol: CCX91662.1
gene_biotype: protein_coding
description:
  Putative beta-lactamase hcpC; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.


ensembl_gene_id: BN779_00572
symbol: CCX91665.1
gene_biotype: protein_coding
description:
  Uncharacterized protein; Hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives.


ensembl_gene_id: BN779_00574
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: BN779_00575
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: BN779_00578
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: BN779_00579
symbol: CCX91677.1
gene_biotype: protein_coding
description:
  (Glutamine-N5) methyltransferase ribosomal protein L3-specific; Product inferred by homology to UniProt; Belongs to the protein N5-glutamine methyltransferase family.


ensembl_gene_id: BN779_00583
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: BN779_00586
symbol: CCX91686.1
gene_biotype: protein_coding
description:
  Integration host factor subunit beta; Product inferred by homology to UniProt; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: BN779_00589
symbol: ribA
gene_biotype: protein_coding
description:
  gTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: BN779_00593
symbol: CCX91708.1
gene_biotype: protein_coding
description:
  cDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Product inferred by homology to UniProt; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: BN779_00594
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: BN779_00600
symbol: CCX91719.1
gene_biotype: protein_coding
description:
  Putative bifunctional protein FolC; Product inferred by homology to UniProt; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: BN779_00601
symbol: accD
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: BN779_00610
symbol: CCX91732.1
gene_biotype: protein_coding
description:
  Probable intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: BN779_00615
symbol: fur
gene_biotype: protein_coding
description:
  Ferric uptake regulator Fur family; Product inferred by homology to UniProt; Belongs to the Fur family.


ensembl_gene_id: BN779_00626
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: BN779_00627
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: BN779_00632
symbol: rpoC
gene_biotype: protein_coding
description:
  dNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BN779_00634
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: BN779_00635
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: BN779_00636
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: BN779_00637
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: BN779_00638
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: BN779_00639
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: BN779_00645
symbol: clpB
gene_biotype: protein_coding
description:
  aTP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: BN779_00646
symbol: CCX91818.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: BN779_00647
symbol: CCX91819.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: BN779_00648
symbol: bamD
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BN779_00654
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: BN779_00655
symbol: CCX91831.1
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase 1; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). Belongs to the DapA family.


ensembl_gene_id: BN779_00656
symbol: lysS
gene_biotype: protein_coding
description:
  lysine--tRNA ligase; Product inferred by homology to UniProt; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: BN779_00657
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: BN779_00658
symbol: CCX91841.1
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide diphosphorylase (Carboxylating); Product inferred by homology to UniProt; Belongs to the NadC/ModD family.


ensembl_gene_id: BN779_00659
symbol: CCX91842.1
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: BN779_00660
symbol: CCX91843.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: BN779_00665
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: BN779_00669
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: BN779_00671
symbol: CCX91863.1
gene_biotype: protein_coding
description:
  Nitrogen regulatory protein P-II; Product inferred by homology to UniProt; Belongs to the P(II) protein family.


ensembl_gene_id: BN779_00674
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: BN779_00676
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: BN779_00680
symbol: CCX91900.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BN779_00688
symbol: CCX91928.1
gene_biotype: protein_coding
description:
  Transcriptional regulator IclR family C-terminal domain protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00690
symbol: CCX91930.1
gene_biotype: protein_coding
description:
  Two-component system flagellar sensor histidine kinase FlrB; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00700
symbol: der
gene_biotype: protein_coding
description:
  gTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: BN779_00701
symbol: bamB
gene_biotype: protein_coding
description:
  Outer membrane assembly lipoprotein YfgL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BN779_00704
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: BN779_00706
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: BN779_00709
symbol: cobB
gene_biotype: protein_coding
description:
  Transcriptional regulator Sir2 family; Product inferred by homology to UniProt; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: BN779_00714
symbol: secF
gene_biotype: protein_coding
description:
  Protein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: BN779_00715
symbol: secD
gene_biotype: protein_coding
description:
  Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: BN779_00716
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: BN779_00717
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: BN779_00718
symbol: queA
gene_biotype: protein_coding
description:
  s-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: BN779_00726
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: BN779_00727
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: BN779_00729
symbol: CCX92009.1
gene_biotype: protein_coding
description:
  Putative DnaA regulatory inactivator Hda; Product inferred by homology to UniProt; Belongs to the DnaA family.


ensembl_gene_id: BN779_00732
symbol: CCX92012.1
gene_biotype: protein_coding
description:
  Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.


ensembl_gene_id: BN779_00737
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: BN779_00738
symbol: dnaQ
gene_biotype: protein_coding
description:
  dNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: BN779_00741
symbol: ligA
gene_biotype: protein_coding
description:
  dNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: BN779_00742
symbol: CCX92033.1
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.


ensembl_gene_id: BN779_00749
symbol: CCX92041.1
gene_biotype: protein_coding
description:
  nAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: BN779_00750
symbol: CCX92043.1
gene_biotype: protein_coding
description:
  nAD(P)(+) transhydrogenase (AB-specific) alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: BN779_00753
symbol: minC
gene_biotype: protein_coding
description:
  Putative septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: BN779_00755
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: BN779_00756
symbol: CCX92061.1
gene_biotype: protein_coding
description:
  Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: BN779_00757
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: BN779_00758
symbol: parE
gene_biotype: protein_coding
description:
  dNA topoisomerase IV B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: BN779_00763
symbol: cpdA
gene_biotype: protein_coding
description:
  3' 5'-cyclic adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: BN779_00767
symbol: CCX92072.1
gene_biotype: protein_coding
description:
  Ribulose-phosphate 3-epimerase; Product inferred by homology to UniProt; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: BN779_00769
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: BN779_00770
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: BN779_00774
symbol: groL
gene_biotype: protein_coding
description:
  60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: BN779_00775
symbol: groS
gene_biotype: protein_coding
description:
  10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: BN779_00782
symbol: CCX92101.1
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgC; Product inferred by homology to UniProt; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: BN779_00783
symbol: CCX92102.1
gene_biotype: protein_coding
description:
  Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: BN779_00788
symbol: CCX92111.1
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring biosynthesis protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: BN779_00793
symbol: CCX92118.1
gene_biotype: protein_coding
description:
  aTPase family associated with various cellular activities (AAA); Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00800
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: BN779_00801
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: BN779_00802
symbol: tolB
gene_biotype: protein_coding
description:
  Protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: BN779_00804
symbol: tolR
gene_biotype: protein_coding
description:
  Transport energizing protein ExbD/TolR family; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: BN779_00805
symbol: tolQ
gene_biotype: protein_coding
description:
  Protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: BN779_00808
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: BN779_00809
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: BN779_00817
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: BN779_00818
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex RnfABCDGE type E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: BN779_00820
symbol: CCX92160.1
gene_biotype: protein_coding
description:
  Putative electron transport complex protein RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: BN779_00821
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex RnfABCDGE type C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: BN779_00822
symbol: CCX92162.1
gene_biotype: protein_coding
description:
  Electron transport complex RnfABCDGE type B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: BN779_00823
symbol: CCX92163.1
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: BN779_00824
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: BN779_00829
symbol: metN
gene_biotype: protein_coding
description:
  aBC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: BN779_00848
symbol: metG
gene_biotype: protein_coding
description:
  methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: BN779_00853
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: BN779_00854
symbol: CCX92211.1
gene_biotype: protein_coding
description:
  Acetyltransferase GNAT family; Product inferred by homology to UniProt; Belongs to the acetyltransferase family.


ensembl_gene_id: BN779_00859
symbol: gyrB
gene_biotype: protein_coding
description:
  dNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: BN779_00860
symbol: recF
gene_biotype: protein_coding
description:
  dNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: BN779_00861
symbol: CCX92236.1
gene_biotype: protein_coding
description:
  dNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: BN779_00862
symbol: CCX92238.1
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.


ensembl_gene_id: BN779_00863
symbol: rpmH
gene_biotype: protein_coding
description:
  50S ribosomal protein L34; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: BN779_00864
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: BN779_00865
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: BN779_00869
symbol: CCX92255.1
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: BN779_00873
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: BN779_00875
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: BN779_00876
symbol: rsmG
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: BN779_00880
symbol: atpB
gene_biotype: protein_coding
description:
  aTP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: BN779_00881
symbol: atpE
gene_biotype: protein_coding
description:
  aTP synthase F0 C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: BN779_00882
symbol: atpF
gene_biotype: protein_coding
description:
  aTP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: BN779_00883
symbol: atpH
gene_biotype: protein_coding
description:
  aTP synthase; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: BN779_00884
symbol: atpA
gene_biotype: protein_coding
description:
  aTP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: BN779_00886
symbol: atpD
gene_biotype: protein_coding
description:
  aTP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: BN779_00887
symbol: atpC
gene_biotype: protein_coding
description:
  aTP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: BN779_00888
symbol: CCX92295.1
gene_biotype: protein_coding
description:
  rNA methyltransferase RsmD family; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: BN779_00889
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: BN779_00890
symbol: rpoH
gene_biotype: protein_coding
description:
  rNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: BN779_00891
symbol: CCX92298.1
gene_biotype: protein_coding
description:
  Putative 3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: BN779_00893
symbol: lptA
gene_biotype: protein_coding
description:
  Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: BN779_00894
symbol: CCX92302.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide ABC transporter ATP-binding protein LptB; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00895
symbol: CCX92305.1
gene_biotype: protein_coding
description:
  rNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: BN779_00904
symbol: CCX92329.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the UPF0307 family.


ensembl_gene_id: BN779_00906
symbol: CCX92333.1
gene_biotype: protein_coding
description:
  Maf-like protein HMPREF9444_00975; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: BN779_00907
symbol: CCX92335.1
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: BN779_00910
symbol: CCX92344.1
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: BN779_00911
symbol: uvrA
gene_biotype: protein_coding
description:
  uvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: BN779_00918
symbol: CCX92363.1
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: BN779_00919
symbol: CCX92365.1
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate O-acyltransferase; Product inferred by homology to UniProt; Belongs to the GPAT/DAPAT family.


ensembl_gene_id: BN779_00920
symbol: CCX92367.1
gene_biotype: protein_coding
description:
  Ferrous iron efflux protein F; Product inferred by homology to UniProt; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: BN779_00923
symbol: hslU
gene_biotype: protein_coding
description:
  aTP-dependent protease ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: BN779_00924
symbol: hslV
gene_biotype: protein_coding
description:
  aTP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: BN779_00927
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: BN779_00929
symbol: CCX92380.1
gene_biotype: protein_coding
description:
  Putative malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+)); Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00938
symbol: CCX92396.1
gene_biotype: protein_coding
description:
  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: BN779_00940
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: BN779_00941
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: BN779_00942
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: BN779_00948
symbol: queE
gene_biotype: protein_coding
description:
  Hypothetical phage protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: BN779_00950
symbol: CCX92423.1
gene_biotype: protein_coding
description:
  Competence/damage-inducible protein CinA domain protein; Product inferred by homology to UniProt; Belongs to the CinA family.


ensembl_gene_id: BN779_00958
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: BN779_00960
symbol: CCX92433.1
gene_biotype: protein_coding
description:
  Protein phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: BN779_00961
symbol: CCX92434.1
gene_biotype: protein_coding
description:
  Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_00962
symbol: fliA
gene_biotype: protein_coding
description:
  rNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: BN779_00965
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: BN779_00967
symbol: CCX92440.1
gene_biotype: protein_coding
description:
  rNAse H domain protein YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: BN779_00978
symbol: CCX92459.1
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: BN779_00980
symbol: CCX92461.1
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BN779_00982
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: BN779_00983
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: BN779_00984
symbol: rpmF
gene_biotype: protein_coding
description:
  50S ribosomal protein L32; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: BN779_00989
symbol: rne
gene_biotype: protein_coding
description:
  S1 RNA binding domain protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: BN779_00992
symbol: CCX92478.1
gene_biotype: protein_coding
description:
  Inositol monophosphatase family protein; Product inferred by homology to UniProt; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: BN779_00994
symbol: uvrB
gene_biotype: protein_coding
description:
  uvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]


ensembl_gene_id: BN779_00997
symbol: CCX92489.1
gene_biotype: protein_coding
description:
  Cellulose synthase catalytic subunit (UDP-forming); Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.


ensembl_gene_id: BN779_00998
symbol: CCX92491.1
gene_biotype: protein_coding
description:
  Putative polysaccharide biosynthesis protein subunit B; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: BN779_01012
symbol: carA
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase small chain; Product inferred by homology to UniProt; Belongs to the CarA family.


ensembl_gene_id: BN779_01013
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase large chain; Product inferred by homology to UniProt; Belongs to the CarB family.


ensembl_gene_id: BN779_01015
symbol: msrA
gene_biotype: protein_coding
description:
  methionine-S-sulfoxide reductase/methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: BN779_01022
symbol: CCX92582.1
gene_biotype: protein_coding
description:
  Glutamate dehydrogenase; Product inferred by homology to UniProt; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: BN779_01025
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: BN779_01026
symbol: CCX92586.1
gene_biotype: protein_coding
description:
  Toxin-antitoxin system toxin component GNAT domain protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01028
symbol: nadK
gene_biotype: protein_coding
description:
  Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: BN779_01029
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: BN779_01030
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: BN779_01031
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: BN779_01032
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: BN779_01035
symbol: CCX92597.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Product inferred by homology to UniProt; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: BN779_01037
symbol: CCX92613.1
gene_biotype: protein_coding
description:
  Type I restriction modification DNA specificity domain protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01039
symbol: CCX92615.1
gene_biotype: protein_coding
description:
  aAA ATPase central region; Product inferred by homology to UniProt; Belongs to the AAA ATPase family.


ensembl_gene_id: BN779_01046
symbol: smpB
gene_biotype: protein_coding
description:
  ssrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: BN779_01048
symbol: CCX92629.1
gene_biotype: protein_coding
description:
  Flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: BN779_01052
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: BN779_01053
symbol: fabV
gene_biotype: protein_coding
description:
  Putative reductase HMPREF9444_01824; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: BN779_01054
symbol: CCX92650.1
gene_biotype: protein_coding
description:
  d-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01060
symbol: CCX92666.1
gene_biotype: protein_coding
description:
  Putative ribosomal RNA small subunit methyltransferase B; Product inferred by homology to UniProt; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: BN779_01061
symbol: deaD
gene_biotype: protein_coding
description:
  Cold-shock DEAD-box protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: BN779_01062
symbol: CCX92673.1
gene_biotype: protein_coding
description:
  Ferrous iron transporter B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: BN779_01064
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: BN779_01065
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: BN779_01066
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: BN779_01067
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: BN779_01076
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: BN779_01077
symbol: mltG
gene_biotype: protein_coding
description:
  yceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: BN779_01079
symbol: valS
gene_biotype: protein_coding
description:
  valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: BN779_01082
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: BN779_01083
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: BN779_01085
symbol: CCX92712.1
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibF; Product inferred by homology to UniProt; Belongs to the ribF family.


ensembl_gene_id: BN779_01088
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: BN779_01089
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: BN779_01091
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: BN779_01092
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: BN779_01094
symbol: lpxD
gene_biotype: protein_coding
description:
  uDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: BN779_01096
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: BN779_01098
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: BN779_01099
symbol: CCX92755.1
gene_biotype: protein_coding
description:
  Phosphatidate cytidylyltransferase; Product inferred by homology to UniProt; Belongs to the CDS family.


ensembl_gene_id: BN779_01100
symbol: uppS
gene_biotype: protein_coding
description:
  Ditrans polycis-undecaprenyl-diphosphate synthase ((2E 6E)-farnesyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: BN779_01101
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: BN779_01103
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: BN779_01104
symbol: rpsB
gene_biotype: protein_coding
description:
  30S ribosomal protein S2; Product inferred by homology to UniProt; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: BN779_01105
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: BN779_01106
symbol: glnD
gene_biotype: protein_coding
description:
  Uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: BN779_01107
symbol: dapD
gene_biotype: protein_coding
description:
  2 3 4 5-tetrahydropyridine-2 6-dicarboxylate N-succinyltransferase; Product inferred by homology to UniProt; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: BN779_01109
symbol: nqrF
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: BN779_01110
symbol: nqrE
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: BN779_01111
symbol: nqrD
gene_biotype: protein_coding
description:
  nADH:ubiquinone oxidoreductase D subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: BN779_01112
symbol: nqrC
gene_biotype: protein_coding
description:
  nADH:ubiquinone oxidoreductase Na(+)-translocating C subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: BN779_01113
symbol: nqrB
gene_biotype: protein_coding
description:
  nADH:ubiquinone oxidoreductase B subunit; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: BN779_01114
symbol: CCX92794.1
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: BN779_01118
symbol: CCX92860.1
gene_biotype: protein_coding
description:
  uPF0234 protein HMPREF9444_01472; Product inferred by homology to UniProt; Belongs to the UPF0234 family.


ensembl_gene_id: BN779_01119
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: BN779_01120
symbol: CCX92862.1
gene_biotype: protein_coding
description:
  Geranyltranstransferase; Product inferred by homology to UniProt; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: BN779_01121
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: BN779_01122
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanine--tRNA ligase beta subunit; Product inferred by homology to UniProt; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: BN779_01126
symbol: CCX92871.1
gene_biotype: protein_coding
description:
  Lipoprotein releasing system transmembrane protein LolC/E family; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01127
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: BN779_01133
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: BN779_01138
symbol: CCX92891.1
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme GlgX; Product inferred by homology to UniProt; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BN779_01141
symbol: CCX92908.1
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase type I; Product inferred by homology to UniProt; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: BN779_01143
symbol: htpX
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; Product inferred by homology to UniProt; Belongs to the peptidase M48B family.


ensembl_gene_id: BN779_01149
symbol: CCX92916.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: BN779_01150
symbol: dksA
gene_biotype: protein_coding
description:
  rNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: BN779_01151
symbol: CCX92918.1
gene_biotype: protein_coding
description:
  Putative glutamyl-queuosine tRNA(Asp) synthetase; Product inferred by homology to UniProt; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: BN779_01153
symbol: pcnB
gene_biotype: protein_coding
description:
  Putative polynucleotide adenylyltransferase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: BN779_01155
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: BN779_01156
symbol: ychF
gene_biotype: protein_coding
description:
  gTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: BN779_01159
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: BN779_01160
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: BN779_01161
symbol: CCX92929.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the UPF0255 family.


ensembl_gene_id: BN779_01162
symbol: murJ
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: BN779_01165
symbol: bioC
gene_biotype: protein_coding
description:
  malonyl-CoA O-methyltransferase BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: BN779_01170
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: BN779_01171
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: BN779_01172
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: BN779_01175
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: BN779_01176
symbol: rpmI
gene_biotype: protein_coding
description:
  50S ribosomal protein L35; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: BN779_01177
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: BN779_01178
symbol: thrS
gene_biotype: protein_coding
description:
  threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: BN779_01179
symbol: CCX92954.1
gene_biotype: protein_coding
description:
  Periplasmic binding protein/LacI transcriptional regulator; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01183
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: BN779_01185
symbol: serS
gene_biotype: protein_coding
description:
  serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: BN779_01187
symbol: CCX92967.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: BN779_01188
symbol: CCX92969.1
gene_biotype: protein_coding
description:
  ftsK/SpoIIIE family protein; Product inferred by homology to UniProt; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: BN779_01189
symbol: trmL
gene_biotype: protein_coding
description:
  tRNA (cytidine(34)-2'-O)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: BN779_01199
symbol: CCX92996.1
gene_biotype: protein_coding
description:
  dNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: BN779_01201
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; Product inferred by homology to UniProt; Belongs to the GARS family.


ensembl_gene_id: BN779_01205
symbol: CCX93002.1
gene_biotype: protein_coding
description:
  Regulator of RNA polymerase sigma(70) subunit Rsd/AlgQ; Product inferred by homology to UniProt; Belongs to the Rsd/AlgQ family.


ensembl_gene_id: BN779_01206
symbol: radA
gene_biotype: protein_coding
description:
  dNA repair protein radA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: BN779_01209
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: BN779_01215
symbol: CCX93013.1
gene_biotype: protein_coding
description:
  Hsp20/alpha crystallin family protein; Product inferred by homology to UniProt; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: BN779_01218
symbol: CCX93016.1
gene_biotype: protein_coding
description:
  Flagellin A; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: BN779_01225
symbol: CCX93034.1
gene_biotype: protein_coding
description:
  Peptidase S24-like protein; Product inferred by homology to UniProt; Belongs to the peptidase S24 family.


ensembl_gene_id: BN779_01231
symbol: ddl
gene_biotype: protein_coding
description:
  d-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: BN779_01233
symbol: CCX93057.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: BN779_01234
symbol: polA
gene_biotype: protein_coding
description:
  dNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: BN779_01236
symbol: CCX93060.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: BN779_01237
symbol: cysS
gene_biotype: protein_coding
description:
  cysteine--tRNA ligase; Product inferred by homology to UniProt; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: BN779_01240
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: BN779_01241
symbol: queH
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: BN779_01243
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: BN779_01244
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: BN779_01246
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: BN779_01247
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: BN779_01248
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: BN779_01249
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: BN779_01250
symbol: CCX93080.1
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Product inferred by homology to UniProt; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: BN779_01251
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: BN779_01252
symbol: rpmC
gene_biotype: protein_coding
description:
  50S ribosomal protein L29; Product inferred by homology to UniProt; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: BN779_01253
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: BN779_01254
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: BN779_01255
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: BN779_01256
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: BN779_01257
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: BN779_01258
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: BN779_01259
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: BN779_01260
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: BN779_01261
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: BN779_01263
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: BN779_01264
symbol: secY
gene_biotype: protein_coding
description:
  Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: BN779_01265
symbol: rpmJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L36; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: BN779_01266
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: BN779_01267
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: BN779_01268
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: BN779_01269
symbol: rpoA
gene_biotype: protein_coding
description:
  dNA-directed RNA polymerase subunit alpha 1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BN779_01271
symbol: rpoA-2
gene_biotype: protein_coding
description:
  dNA-directed RNA polymerase subunit alpha 2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BN779_01277
symbol: proC
gene_biotype: protein_coding
description:
  Pyridoxal phosphate enzyme YggS family; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: BN779_01279
symbol: CCX93124.1
gene_biotype: protein_coding
description:
  Transporter small conductance mechanosensitive ion channel MscS family protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01281
symbol: CCX93126.1
gene_biotype: protein_coding
description:
  rNA polymerase sigma factor RpoE; Product inferred by homology to UniProt; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: BN779_01284
symbol: lepA
gene_biotype: protein_coding
description:
  Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: BN779_01286
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: BN779_01287
symbol: era
gene_biotype: protein_coding
description:
  gTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: BN779_01289
symbol: CCX93135.1
gene_biotype: protein_coding
description:
  23S rRNA (Uracil-5-)-methyltransferase RumA; Product inferred by homology to UniProt; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: BN779_01291
symbol: pyrG
gene_biotype: protein_coding
description:
  cTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: BN779_01292
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: BN779_01293
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: BN779_01294
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: BN779_01297
symbol: CCX93149.1
gene_biotype: protein_coding
description:
  rNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: BN779_01298
symbol: mutS
gene_biotype: protein_coding
description:
  dNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: BN779_01299
symbol: recA
gene_biotype: protein_coding
description:
  Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: BN779_01303
symbol: alaS
gene_biotype: protein_coding
description:
  alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: BN779_01310
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: BN779_01315
symbol: CCX93189.1
gene_biotype: protein_coding
description:
  Peptidoglycan amidase MepA; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus.


ensembl_gene_id: BN779_01320
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: BN779_01321
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase 1; Product inferred by homology to UniProt; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: BN779_01324
symbol: CCX93199.1
gene_biotype: protein_coding
description:
  Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.


ensembl_gene_id: BN779_01325
symbol: CCX93203.1
gene_biotype: protein_coding
description:
  Nitrogen fixation protein nifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.


ensembl_gene_id: BN779_01331
symbol: CCX93261.1
gene_biotype: protein_coding
description:
  Putative glycogen debranching enzyme GlgX; Product inferred by homology to UniProt; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BN779_01334
symbol: CCX93267.1
gene_biotype: protein_coding
description:
  Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: BN779_01340
symbol: CCX93280.1
gene_biotype: protein_coding
description:
  Putative putrescine-binding periplasmic protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: BN779_01343
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: BN779_01344
symbol: CCX93284.1
gene_biotype: protein_coding
description:
  Hydrolyase tartrate alpha subunit/fumarate domain protein Fe-S type; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: BN779_01348
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: BN779_01351
symbol: rlmL
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: BN779_01357
symbol: sstT-2
gene_biotype: protein_coding
description:
  Serine/threonine transporter SstT 2; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BN779_01359
symbol: CCX93315.1
gene_biotype: protein_coding
description:
  Membrane bound O-acyl transferase MBOAT family protein; Product inferred by homology to UniProt; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: BN779_01421
symbol: CCX93436.1
gene_biotype: protein_coding
description:
  Pol protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.


ensembl_gene_id: BN779_01428
symbol: thiI
gene_biotype: protein_coding
description:
  tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: BN779_01442
symbol: CCX93498.1
gene_biotype: protein_coding
description:
  Auxiliary transport protein membrane fusion protein (MFP) family protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01446
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Product inferred by homology to UniProt; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: BN779_01447
symbol: pyrI
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.


ensembl_gene_id: BN779_01458
symbol: CCX93535.1
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Product inferred by homology to UniProt; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: BN779_01460
symbol: CCX93541.1
gene_biotype: protein_coding
description:
  Predicted oxidoreductases (Related to aryl-alcohol dehydrogenases); Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01463
symbol: CCX93545.1
gene_biotype: protein_coding
description:
  Uncharacterized protein; Product inferred by homology to UniProt; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BN779_01471
symbol: dnaG
gene_biotype: protein_coding
description:
  dNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: BN779_01475
symbol: CCX93561.1
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: BN779_01476
symbol: obg
gene_biotype: protein_coding
description:
  gTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: BN779_01477
symbol: rpmA
gene_biotype: protein_coding
description:
  50S ribosomal protein L27; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: BN779_01478
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: BN779_01479
symbol: CCX93565.1
gene_biotype: protein_coding
description:
  Putative octaprenyl pyrophosphate synthetase; Product inferred by homology to UniProt; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: BN779_01481
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: BN779_01484
symbol: hflX
gene_biotype: protein_coding
description:
  gTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: BN779_01485
symbol: hfq
gene_biotype: protein_coding
description:
  Protein hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: BN779_01486
symbol: CCX93580.1
gene_biotype: protein_coding
description:
  Putative oligogalactan ABC transporter periplasmic solute-binding protein ganE; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01489
symbol: CCX93583.1
gene_biotype: protein_coding
description:
  mFS transporter SP family; Product inferred by homology to UniProt; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: BN779_01491
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; Product inferred by homology to UniProt; Belongs to the KdsA family.


ensembl_gene_id: BN779_01493
symbol: CCX93596.1
gene_biotype: protein_coding
description:
  Type I restriction enzyme HsdR protein N-terminal domain protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01498
symbol: metN-2
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: BN779_01500
symbol: CCX93608.1
gene_biotype: protein_coding
description:
  Adenylosuccinate lyase; Product inferred by homology to UniProt; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: BN779_01502
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: BN779_01505
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: BN779_01510
symbol: CCX93623.1
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: BN779_01513
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: BN779_01515
symbol: CCX93628.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(Acyl carrier protein) synthase I; Product inferred by homology to UniProt; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: BN779_01520
symbol: CCX93647.1
gene_biotype: protein_coding
description:
  Maltose/maltodextrin ABC transporter; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BN779_01526
symbol: CCX93666.1
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.


ensembl_gene_id: BN779_01527
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: BN779_01528
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01529
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: BN779_01530
symbol: hisB
gene_biotype: protein_coding
description:
  Imidazoleglycerol-phosphate dehydratase; Product inferred by homology to UniProt; In the N-terminal section; belongs to the histidinol- phosphatase family.


ensembl_gene_id: BN779_01531
symbol: hisC-2
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase 2; Product inferred by homology to UniProt; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: BN779_01532
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: BN779_01533
symbol: hisG
gene_biotype: protein_coding
description:
  aTP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: BN779_01535
symbol: CCX93678.1
gene_biotype: protein_coding
description:
  Amine acid ABC transporter permease protein 3-TM region His/Glu/Gln/Arg/opine family; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01536
symbol: CCX93679.1
gene_biotype: protein_coding
description:
  L-glutamate ABC transporter membrane protein/L-aspartate ABC transporter membrane protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01537
symbol: CCX93681.1
gene_biotype: protein_coding
description:
  aBC-type amino acid transport/signal transduction systems periplasmic component/domain; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01540
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: BN779_01541
symbol: nhaB
gene_biotype: protein_coding
description:
  na(+)/H(+) antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: BN779_01549
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: BN779_01550
symbol: clpP
gene_biotype: protein_coding
description:
  aTP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: BN779_01551
symbol: clpX
gene_biotype: protein_coding
description:
  aTP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: BN779_01552
symbol: lon
gene_biotype: protein_coding
description:
  Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: BN779_01556
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: BN779_01557
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: BN779_01567
symbol: glgC-2
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase 2; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: BN779_01576
symbol: prmC
gene_biotype: protein_coding
description:
  Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: BN779_01577
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: BN779_01591
symbol: CCX90093.1
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Product inferred by homology to UniProt; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BN779_01592
symbol: bioD
gene_biotype: protein_coding
description:
  aTP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: BN779_01593
symbol: CCX90095.1
gene_biotype: protein_coding
description:
  Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: BN779_01603
symbol: CCX90122.1
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: BN779_01604
symbol: CCX90123.1
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: BN779_01605
symbol: pgk
gene_biotype: protein_coding
description:
  Phosphoglycerate kinase; Product inferred by homology to UniProt; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: BN779_01606
symbol: CCX90125.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: BN779_01608
symbol: tal
gene_biotype: protein_coding
description:
  Probable transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: BN779_01609
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: BN779_01614
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: BN779_01617
symbol: potA
gene_biotype: protein_coding
description:
  Polyamine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: BN779_01623
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: BN779_01628
symbol: CCX90194.1
gene_biotype: protein_coding
description:
  Cytidine and deoxycytidylate deaminase zinc-binding region; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01629
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: BN779_01630
symbol: CCX90198.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the CvfB family.


ensembl_gene_id: BN779_01632
symbol: topA
gene_biotype: protein_coding
description:
  dNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]


ensembl_gene_id: BN779_01636
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: BN779_01639
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: BN779_01640
symbol: CCX90214.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: BN779_01654
symbol: CCX90249.1
gene_biotype: protein_coding
description:
  Alginate O-acetylation protein; Product inferred by homology to UniProt; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: BN779_01659
symbol: CCX90261.1
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: BN779_01660
symbol: CCX90263.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3 5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: BN779_01661
symbol: CCX90265.1
gene_biotype: protein_coding
description:
  dTDP-glucose 4 6-dehydratase; Product inferred by homology to UniProt; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: BN779_01667
symbol: uvrC
gene_biotype: protein_coding
description:
  uvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: BN779_01668
symbol: CCX90279.1
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis sensory transducer with Cache sensor; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01675
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: BN779_01676
symbol: dnaX
gene_biotype: protein_coding
description:
  dNA polymerase III subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: BN779_01684
symbol: CCX90298.1
gene_biotype: protein_coding
description:
  beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: BN779_01687
symbol: CCX90306.1
gene_biotype: protein_coding
description:
  2-oxoacid:acceptor oxidoreductase delta subunit pyruvate/2-ketoisovalerate family; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01688
symbol: CCX90307.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate enzyme C-terminal TPP binding domain protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01690
symbol: CCX90311.1
gene_biotype: protein_coding
description:
  2-oxoacid:acceptor oxidoreductase gamma subunit pyruvate/2-ketoisovalerate family; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01707
symbol: CCX90353.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the ArsC family.


ensembl_gene_id: BN779_01712
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: BN779_01715
symbol: CCX90361.1
gene_biotype: protein_coding
description:
  Peptidase S41 family; Product inferred by homology to UniProt; Belongs to the peptidase S41A family.


ensembl_gene_id: BN779_01716
symbol: CCX90362.1
gene_biotype: protein_coding
description:
  proQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.


ensembl_gene_id: BN779_01722
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: BN779_01723
symbol: rpsI
gene_biotype: protein_coding
description:
  30S ribosomal protein S9; Product inferred by homology to UniProt; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: BN779_01727
symbol: rsmI
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: BN779_01729
symbol: rsmH
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: BN779_01732
symbol: murE
gene_biotype: protein_coding
description:
  uDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: BN779_01733
symbol: murF
gene_biotype: protein_coding
description:
  uDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: BN779_01734
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: BN779_01735
symbol: murD
gene_biotype: protein_coding
description:
  uDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: BN779_01737
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: BN779_01740
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein ftsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: BN779_01741
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: BN779_01743
symbol: lpxC
gene_biotype: protein_coding
description:
  uDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: BN779_01745
symbol: CCX90395.1
gene_biotype: protein_coding
description:
  Aconitate hydratase 2; Product inferred by homology to UniProt; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: BN779_01749
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: BN779_01750
symbol: rpsP
gene_biotype: protein_coding
description:
  30S ribosomal protein S16; Product inferred by homology to UniProt; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: BN779_01751
symbol: rimM
gene_biotype: protein_coding
description:
  Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: BN779_01752
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: BN779_01753
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: BN779_01758
symbol: mutH
gene_biotype: protein_coding
description:
  Putative DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: BN779_01759
symbol: rppH
gene_biotype: protein_coding
description:
  rNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: BN779_01761
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: BN779_01763
symbol: CCX90436.1
gene_biotype: protein_coding
description:
  aTP-dependent RNA helicase SrmB; Product inferred by homology to UniProt; Belongs to the DEAD box helicase family.


ensembl_gene_id: BN779_01787
symbol: CCX90474.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: BN779_01788
symbol: CCX90476.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: BN779_01789
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: BN779_01790
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: BN779_01791
symbol: CCX90481.1
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: BN779_01793
symbol: ribH
gene_biotype: protein_coding
description:
  6 7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: BN779_01794
symbol: nusB
gene_biotype: protein_coding
description:
  N utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: BN779_01795
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: BN779_01822
symbol: CCX90515.1
gene_biotype: protein_coding
description:
  Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: BN779_01823
symbol: CCX90516.1
gene_biotype: protein_coding
description:
  Flagellar basal body rod protein FlgF; Product inferred by homology to UniProt; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: BN779_01824
symbol: CCX90517.1
gene_biotype: protein_coding
description:
  Flagellar basal body rod protein FlgG; Product inferred by homology to UniProt; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: BN779_01825
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: BN779_01826
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: BN779_01832
symbol: proS
gene_biotype: protein_coding
description:
  proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]


ensembl_gene_id: BN779_01834
symbol: CCX90533.1
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: BN779_01835
symbol: mpl
gene_biotype: protein_coding
description:
  uDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: BN779_01842
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: BN779_01843
symbol: CCX90545.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: BN779_01850
symbol: CCX90567.1
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine protein phosphatase; Product inferred by homology to UniProt; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: BN779_01873
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: BN779_01874
symbol: CCX90599.1
gene_biotype: protein_coding
description:
  Putative DNA polymerase subunit UmuD; Product inferred by homology to UniProt; Belongs to the peptidase S24 family.


ensembl_gene_id: BN779_01875
symbol: CCX90600.1
gene_biotype: protein_coding
description:
  Semialdehyde dehydrogenase dimerization domain protein; Product inferred by homology to UniProt; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: BN779_01886
symbol: tatC-2
gene_biotype: protein_coding
description:
  Sec-independent protein translocase TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: BN779_01893
symbol: CCX90667.1
gene_biotype: protein_coding
description:
  Putative toxin-antitoxin system toxin component Fic family; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01894
symbol: miaB
gene_biotype: protein_coding
description:
  (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: BN779_01896
symbol: ybeY
gene_biotype: protein_coding
description:
  Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: BN779_01898
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: BN779_01903
symbol: leuS
gene_biotype: protein_coding
description:
  leucine--tRNA ligase; Product inferred by homology to UniProt; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: BN779_01904
symbol: CCX90678.1
gene_biotype: protein_coding
description:
  Rare lipoprotein B family protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: BN779_01906
symbol: nadD
gene_biotype: protein_coding
description:
  Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: BN779_01907
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: BN779_01908
symbol: rlmH
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: BN779_01909
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: BN779_01910
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: BN779_01912
symbol: rlpA
gene_biotype: protein_coding
description:
  Sporulation and cell division repeat protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: BN779_01913
symbol: CCX90689.1
gene_biotype: protein_coding
description:
  d-alanyl-D-alanine carboxypeptidase DacA; Product inferred by homology to UniProt; Belongs to the peptidase S11 family.


ensembl_gene_id: BN779_01914
symbol: CCX90690.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein; Product inferred by homology to UniProt; Belongs to the UPF0250 family.


ensembl_gene_id: BN779_01920
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: BN779_01922
symbol: CCX90699.1
gene_biotype: protein_coding
description:
  rNA methyltransferase TrmH family group 3; Product inferred by homology to UniProt; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: BN779_01923
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: BN779_01924
symbol: CCX90708.1
gene_biotype: protein_coding
description:
  Putative oxygen-independent coproporphyrinogen III oxidase; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01925
symbol: CCX90713.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: BN779_01931
symbol: secA
gene_biotype: protein_coding
description:
  Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: BN779_01935
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: BN779_01937
symbol: CCX90739.1
gene_biotype: protein_coding
description:
  Fumarate reductase iron-sulfur subunit; Product inferred by homology to UniProt; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: BN779_01943
symbol: CCX90761.1
gene_biotype: protein_coding
description:
  Gamma-carboxymuconolactone decarboxylase subunit-like protein; Product inferred by homology to UniProt.


ensembl_gene_id: BN779_01955
symbol: CCX90778.1
gene_biotype: protein_coding
description:
  degT/DnrJ/EryC1/StrS aminotransferase; Product inferred by homology to UniProt; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: BN779_01958
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: BN779_01966
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: BN779_01967
symbol: CCX90793.1
gene_biotype: protein_coding
description:
  Indolepyruvate ferredoxin oxidoreductase alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: BN779_01968
symbol: CCX90794.1
gene_biotype: protein_coding
description:
  Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases gamma subunit; Product inferred by homology to UniProt.


