# geneInfo

ensembl_gene_id: MFLO_00010
symbol: EUJ33594.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4473 Predicted ABC-type exoprotein transport system, permease component.


ensembl_gene_id: MFLO_00025
symbol: EUJ33597.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: MFLO_00040
symbol: prsA
gene_biotype: protein_coding
description:
  Hypothetical protein; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.


ensembl_gene_id: MFLO_00075
symbol: EUJ33607.1
gene_biotype: protein_coding
description:
  mutT/nudix family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: MFLO_00095
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: MFLO_00125
symbol: EUJ33613.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein); overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_00135
symbol: EUJ33615.1
gene_biotype: protein_coding
description:
  Arsenate reductase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: MFLO_00140
symbol: EUJ33616.1
gene_biotype: protein_coding
description:
  Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MFLO_00150
symbol: EUJ33618.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: MFLO_00195
symbol: EUJ33627.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: MFLO_00260
symbol: addB
gene_biotype: protein_coding
description:
  ATP-dependent nuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily.


ensembl_gene_id: MFLO_00280
symbol: EUJ33644.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: MFLO_00290
symbol: EUJ33646.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: MFLO_00300
symbol: EUJ33648.1
gene_biotype: protein_coding
description:
  Putative GNAT family N-acetyl transferase; COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.


ensembl_gene_id: MFLO_00305
symbol: azoR
gene_biotype: protein_coding
description:
  Azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: MFLO_00330
symbol: EUJ33654.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein/permease; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: MFLO_00365
symbol: EUJ33659.1
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: MFLO_00375
symbol: EUJ33661.1
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: MFLO_00420
symbol: EUJ33668.1
gene_biotype: protein_coding
description:
  Glycine betaine/L-proline ABC transporter substrate-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: MFLO_00425
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_00435
symbol: EUJ33671.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: MFLO_00455
symbol: EUJ33675.1
gene_biotype: protein_coding
description:
  Putative drug efflux/lipid export ABC transporter, ATP-binding and permease protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: MFLO_00460
symbol: EUJ33676.1
gene_biotype: protein_coding
description:
  Multidrug ABC exporter, ATP-binding subunit; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: MFLO_00470
symbol: EUJ33678.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: MFLO_00475
symbol: EUJ33679.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: MFLO_00495
symbol: EUJ33683.1
gene_biotype: protein_coding
description:
  Amidohydrolase family protein; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.


ensembl_gene_id: MFLO_00510
symbol: EUJ33686.1
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: MFLO_00565
symbol: EUJ33695.1
gene_biotype: protein_coding
description:
  Transcriptional activator, Rgg/GadR/MutR family,C-terminal domain-containing protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: MFLO_00630
symbol: EUJ33704.1
gene_biotype: protein_coding
description:
  Lactose ABC transporter substrate-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: MFLO_00690
symbol: EUJ33716.1
gene_biotype: protein_coding
description:
  Propionate CoA-transferase; COG4670 Acyl CoA:acetate/3-ketoacid CoA transferase; Belongs to the 3-oxoacid CoA-transferase family.


ensembl_gene_id: MFLO_00700
symbol: EUJ33718.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_00750
symbol: EUJ33728.1
gene_biotype: protein_coding
description:
  NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: MFLO_00775
symbol: EUJ33733.1
gene_biotype: protein_coding
description:
  PTS system transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.


ensembl_gene_id: MFLO_00780
symbol: EUJ33734.1
gene_biotype: protein_coding
description:
  aryl-phospho-beta-D-glucosidase BglH domain-containing protein; COG1447 Phosphotransferase system cellobiose-specific component IIA.


ensembl_gene_id: MFLO_00785
symbol: EUJ33735.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase family protein; COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: MFLO_00810
symbol: EUJ33740.1
gene_biotype: protein_coding
description:
  COG0477 Permeases of the major facilitator superfamily; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_00915
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: MFLO_00920
symbol: EUJ33754.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: MFLO_00960
symbol: EUJ33762.1
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: MFLO_00975
symbol: EUJ33765.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: MFLO_00985
symbol: metN
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: MFLO_01080
symbol: EUJ33782.1
gene_biotype: protein_coding
description:
  Virulence factor esxA; COG4842 Uncharacterized protein conserved in bacteria; Belongs to the WXG100 family.


ensembl_gene_id: MFLO_01175
symbol: EUJ33799.1
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: MFLO_01185
symbol: EUJ33801.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MFLO_01195
symbol: EUJ33803.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: MFLO_01200
symbol: EUJ33804.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: MFLO_01225
symbol: EUJ33809.1
gene_biotype: protein_coding
description:
  beta-1,4-N-acetyl-mannosaminyltransferase; COG1922 Teichoic acid biosynthesis proteins; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: MFLO_01315
symbol: EUJ33825.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: MFLO_01375
symbol: EUJ33835.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: MFLO_01385
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: MFLO_01400
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: MFLO_01405
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: MFLO_01410
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: MFLO_01425
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: MFLO_01430
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: MFLO_01440
symbol: EUJ33848.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: MFLO_01450
symbol: EUJ33850.1
gene_biotype: protein_coding
description:
  COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: MFLO_01455
symbol: mrnC
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.


ensembl_gene_id: MFLO_01475
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: MFLO_01480
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: MFLO_01485
symbol: ispD-2
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: MFLO_01495
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: MFLO_01535
symbol: EUJ33865.1
gene_biotype: protein_coding
description:
  Regulatory helix-turn-helix lysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MFLO_01580
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: MFLO_01585
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: MFLO_01630
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: MFLO_01635
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: MFLO_01645
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: MFLO_01650
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: MFLO_01655
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: MFLO_01660
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: MFLO_01670
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: MFLO_01675
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: MFLO_01680
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: MFLO_01685
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: MFLO_01690
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: MFLO_01695
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: MFLO_01700
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: MFLO_01705
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: MFLO_01710
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: MFLO_01720
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: MFLO_01725
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: MFLO_01730
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: MFLO_01735
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: MFLO_01740
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: MFLO_01745
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: MFLO_01755
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: MFLO_01760
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: MFLO_01765
symbol: ecfT
gene_biotype: protein_coding
description:
  Cobalt transport permease; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: MFLO_01775
symbol: EUJ33909.1
gene_biotype: protein_coding
description:
  Thiamine biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: MFLO_01785
symbol: EUJ33911.1
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide family oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: MFLO_01800
symbol: EUJ33914.1
gene_biotype: protein_coding
description:
  Polyprenyl synthase, component II; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: MFLO_01830
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: MFLO_01835
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: MFLO_01840
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: MFLO_01845
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: MFLO_01875
symbol: EUJ33927.1
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG0232 dGTP triphosphohydrolase; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_01885
symbol: EUJ33929.1
gene_biotype: protein_coding
description:
  COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: MFLO_01950
symbol: EUJ33942.1
gene_biotype: protein_coding
description:
  FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_01990
symbol: EUJ33948.1
gene_biotype: protein_coding
description:
  Putative two components response regulator KdpE; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: MFLO_02005
symbol: kdpC
gene_biotype: protein_coding
description:
  K+-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: MFLO_02010
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: MFLO_02015
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: MFLO_02020
symbol: EUJ33952.1
gene_biotype: protein_coding
description:
  PTS system beta-glucoside-specific transporter subunit IIB; COG1440 Phosphotransferase system cellobiose-specific component IIB.


ensembl_gene_id: MFLO_02025
symbol: EUJ33953.1
gene_biotype: protein_coding
description:
  PTS system beta-glucoside-specific transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.


ensembl_gene_id: MFLO_02035
symbol: EUJ33955.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: MFLO_02045
symbol: EUJ33957.1
gene_biotype: protein_coding
description:
  Rhamnulokinase; COG1070 Sugar (pentulose and hexulose) kinases; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_02060
symbol: rhaD
gene_biotype: protein_coding
description:
  Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.


ensembl_gene_id: MFLO_02097
symbol: polC
gene_biotype: protein_coding
description:
  DNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: MFLO_02102
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyla [...]


ensembl_gene_id: MFLO_02117
symbol: EUJ33548.1
gene_biotype: protein_coding
description:
  COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_02122
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: MFLO_02132
symbol: EUJ33551.1
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: MFLO_02137
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: MFLO_02157
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: MFLO_02202
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: MFLO_02237
symbol: EUJ33572.1
gene_biotype: protein_coding
description:
  MutT/nudix hydrolase family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: MFLO_02242
symbol: EUJ33573.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: MFLO_02247
symbol: EUJ33574.1
gene_biotype: protein_coding
description:
  COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: MFLO_02257
symbol: EUJ33576.1
gene_biotype: protein_coding
description:
  O-succinylbenzoic acid--CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_02267
symbol: menB
gene_biotype: protein_coding
description:
  Dihydroxynaphthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: MFLO_02272
symbol: menH
gene_biotype: protein_coding
description:
  Alpha/beta fold family hydrolase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: MFLO_02297
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: MFLO_02358
symbol: EUJ33508.1
gene_biotype: protein_coding
description:
  Teichoic acid-binding N-acetylmuramoyl L-alalanine amidase; COG5632 N-acetylmuramoyl-L-alanine amidase.


ensembl_gene_id: MFLO_02408
symbol: EUJ33518.1
gene_biotype: protein_coding
description:
  Gp15 proteinprotein; COG5283 Phage-related tail protein; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_02593
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: MFLO_02613
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: MFLO_02623
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: MFLO_02723
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: MFLO_02733
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: MFLO_02738
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: MFLO_02758
symbol: EUJ33436.1
gene_biotype: protein_coding
description:
  COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: MFLO_02763
symbol: EUJ33437.1
gene_biotype: protein_coding
description:
  S-formylglutathione hydrolase YeiG; Serine hydrolase involved in the detoxification of formaldehyde.


ensembl_gene_id: MFLO_02768
symbol: EUJ33438.1
gene_biotype: protein_coding
description:
  UPF0109 protein; COG1837 Predicted RNA-binding protein (contains KH domain); lin1910; Belongs to the UPF0109 family.


ensembl_gene_id: MFLO_02788
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: MFLO_02793
symbol: EUJ33443.1
gene_biotype: protein_coding
description:
  DNA-binding protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.


ensembl_gene_id: MFLO_02798
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: MFLO_02813
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: MFLO_02823
symbol: EUJ33447.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MFLO_02833
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: MFLO_02838
symbol: fapR
gene_biotype: protein_coding
description:
  Fatty acid biosynthesis transcriptional regulator; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.


ensembl_gene_id: MFLO_02853
symbol: EUJ33451.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: MFLO_02858
symbol: EUJ33452.1
gene_biotype: protein_coding
description:
  L-serine dehydratase, iron-sulfur-dependent subunit beta; COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: MFLO_02893
symbol: rsgA
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: MFLO_02908
symbol: EUJ33462.1
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: MFLO_02923
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: MFLO_02928
symbol: EUJ33464.1
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_02933
symbol: EUJ33465.1
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: MFLO_02938
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: MFLO_03003
symbol: EUJ33477.1
gene_biotype: protein_coding
description:
  Putative N-acyl-L-amino acid amidohydrolase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.


ensembl_gene_id: MFLO_03008
symbol: dapH
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.


ensembl_gene_id: MFLO_03048
symbol: EUJ33486.1
gene_biotype: protein_coding
description:
  mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein; COG1705 Muramidase (flagellum-specific).


ensembl_gene_id: MFLO_03078
symbol: EUJ33492.1
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: MFLO_03108
symbol: EUJ33498.1
gene_biotype: protein_coding
description:
  Putative FMN-containing NADPH-linked nitro/flavin reductase; COG0778 Nitroreductase; Belongs to the flavin oxidoreductase frp family.


ensembl_gene_id: MFLO_03128
symbol: EUJ33502.1
gene_biotype: protein_coding
description:
  Putative metabolite uptake ABC transporter, permease protein; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: MFLO_03165
symbol: EUJ33308.1
gene_biotype: protein_coding
description:
  Polypeptide deformylase; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: MFLO_03185
symbol: trmFO
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase Gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: MFLO_03190
symbol: xerC
gene_biotype: protein_coding
description:
  Integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: MFLO_03195
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: MFLO_03200
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: MFLO_03205
symbol: codY
gene_biotype: protein_coding
description:
  Transcriptional repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.


ensembl_gene_id: MFLO_03225
symbol: plsY
gene_biotype: protein_coding
description:
  Membrane protein YgiH; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: MFLO_03235
symbol: EUJ33320.1
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_03245
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.


ensembl_gene_id: MFLO_03250
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: MFLO_03265
symbol: EUJ33326.1
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: MFLO_03270
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: MFLO_03275
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: MFLO_03310
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: MFLO_03325
symbol: EUJ33338.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: MFLO_03340
symbol: EUJ33341.1
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: MFLO_03355
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: MFLO_03385
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: MFLO_03390
symbol: EUJ33346.1
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: MFLO_03415
symbol: ybeY
gene_biotype: protein_coding
description:
  Metal-binding heat shock protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: MFLO_03425
symbol: EUJ33353.1
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: MFLO_03430
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: MFLO_03455
symbol: EUJ33359.1
gene_biotype: protein_coding
description:
  PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: MFLO_03460
symbol: EUJ33360.1
gene_biotype: protein_coding
description:
  UPF0178 protein; COG1671 Uncharacterized protein conserved in bacteria; Belongs to the UPF0178 family.


ensembl_gene_id: MFLO_03475
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: MFLO_03500
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: MFLO_03505
symbol: cshB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.


ensembl_gene_id: MFLO_03510
symbol: nfo
gene_biotype: protein_coding
description:
  Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: MFLO_03535
symbol: EUJ33373.1
gene_biotype: protein_coding
description:
  Transcriptional regulator ZurR (ferric uptake regulation); COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: MFLO_03550
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: MFLO_03560
symbol: EUJ33378.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: MFLO_03575
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: MFLO_03585
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: MFLO_03605
symbol: EUJ33385.1
gene_biotype: protein_coding
description:
  Putative glutathione reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: MFLO_03640
symbol: EUJ33392.1
gene_biotype: protein_coding
description:
  Carnitine transport ATP-binding protein OpuCA; COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


ensembl_gene_id: MFLO_03650
symbol: EUJ33394.1
gene_biotype: protein_coding
description:
  COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: MFLO_03655
symbol: EUJ33395.1
gene_biotype: protein_coding
description:
  Carnitine transport permease protein OpuCD; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: MFLO_03660
symbol: mntH
gene_biotype: protein_coding
description:
  Manganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: MFLO_03670
symbol: EUJ33398.1
gene_biotype: protein_coding
description:
  Glycine betaine/L-proline ABC transporter permease/substrate-binding protein; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: MFLO_03675
symbol: EUJ33399.1
gene_biotype: protein_coding
description:
  glycine/betaine/L-proline ABC transporter ATP-binding protein; COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


ensembl_gene_id: MFLO_03690
symbol: EUJ33214.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: MFLO_03700
symbol: EUJ33216.1
gene_biotype: protein_coding
description:
  Putative type I phosphodiesterase/nucleotide pyrophosphatase family protein; COG1524 Uncharacterized proteins of the AP superfamily.


ensembl_gene_id: MFLO_03745
symbol: EUJ33225.1
gene_biotype: protein_coding
description:
  Pyruvate-formate lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: MFLO_03750
symbol: EUJ33226.1
gene_biotype: protein_coding
description:
  Glycerol uptake responsive antiterminator; Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.


ensembl_gene_id: MFLO_03755
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: MFLO_03760
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: MFLO_03790
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: MFLO_03795
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: MFLO_03800
symbol: EUJ33236.1
gene_biotype: protein_coding
description:
  COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: MFLO_03815
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: MFLO_03840
symbol: minC
gene_biotype: protein_coding
description:
  Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: MFLO_03870
symbol: EUJ33248.1
gene_biotype: protein_coding
description:
  Signal peptidase; COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; cleaves prepilin-like proteins.


ensembl_gene_id: MFLO_03880
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: MFLO_03905
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: MFLO_03915
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: MFLO_03920
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: MFLO_03925
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: MFLO_03930
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: MFLO_03935
symbol: EUJ33257.1
gene_biotype: protein_coding
description:
  Primosomal protein DnaI; COG1484 DNA replication protein; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_03945
symbol: EUJ33259.1
gene_biotype: protein_coding
description:
  COG3611 Replication initiation/membrane attachment protein; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_03960
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: MFLO_03965
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: MFLO_03970
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: MFLO_03975
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.


ensembl_gene_id: MFLO_04015
symbol: EUJ33273.1
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: MFLO_04025
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: MFLO_04030
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: MFLO_04050
symbol: EUJ33280.1
gene_biotype: protein_coding
description:
  COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Belongs to the UPF0173 family.


ensembl_gene_id: MFLO_04080
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: MFLO_04090
symbol: tpx
gene_biotype: protein_coding
description:
  Lipid hydroperoxide peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: MFLO_04105
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: MFLO_04110
symbol: EUJ33292.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: MFLO_04115
symbol: ezrA
gene_biotype: protein_coding
description:
  Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.


ensembl_gene_id: MFLO_04125
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: MFLO_04135
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: MFLO_04155
symbol: EUJ33301.1
gene_biotype: protein_coding
description:
  COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain.


ensembl_gene_id: MFLO_04230
symbol: EUJ33119.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family protein; COG0582 Integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: MFLO_04235
symbol: EUJ33120.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes.


ensembl_gene_id: MFLO_04245
symbol: EUJ33122.1
gene_biotype: protein_coding
description:
  Transcriptional activator Rgg/GadR/MutR domain-containing protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: MFLO_04300
symbol: EUJ33133.1
gene_biotype: protein_coding
description:
  Cell division FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins.


ensembl_gene_id: MFLO_04465
symbol: fhs
gene_biotype: protein_coding
description:
  Formate--tetrahydrofolate ligase; COG2759 Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: MFLO_04490
symbol: queH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: MFLO_04500
symbol: EUJ33167.1
gene_biotype: protein_coding
description:
  PhnA protein; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: MFLO_04505
symbol: EUJ33168.1
gene_biotype: protein_coding
description:
  Flavodoxin-like fold family protein; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: MFLO_04510
symbol: EUJ33169.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding domain-containing protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: MFLO_04530
symbol: EUJ33171.1
gene_biotype: protein_coding
description:
  Glucose 1-dehydrogenase 2; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_04535
symbol: EUJ33172.1
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: MFLO_04550
symbol: EUJ33175.1
gene_biotype: protein_coding
description:
  DSBA-like thioredoxin domain-containing protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: MFLO_04590
symbol: EUJ33183.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, Bcr/CflA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: MFLO_04615
symbol: EUJ33188.1
gene_biotype: protein_coding
description:
  PP-loop domain-containing protein; COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family.


ensembl_gene_id: MFLO_04690
symbol: EUJ33203.1
gene_biotype: protein_coding
description:
  Transporter, anaerobic C4-dicarboxylate uptake C family protein; COG3069 C4-dicarboxylate transporter.


ensembl_gene_id: MFLO_04695
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: MFLO_04700
symbol: EUJ33205.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.


ensembl_gene_id: MFLO_04715
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: MFLO_04745
symbol: EUJ32905.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: MFLO_04755
symbol: xerD
gene_biotype: protein_coding
description:
  Integrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: MFLO_04760
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: MFLO_04765
symbol: EUJ32909.1
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


ensembl_gene_id: MFLO_04770
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: MFLO_04775
symbol: scpA
gene_biotype: protein_coding
description:
  Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: MFLO_04780
symbol: scpB
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: MFLO_04785
symbol: EUJ32913.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: MFLO_04815
symbol: EUJ32917.1
gene_biotype: protein_coding
description:
  Riboflavin transporter FmnP; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.


ensembl_gene_id: MFLO_04870
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: MFLO_04875
symbol: EUJ32927.1
gene_biotype: protein_coding
description:
  Heptaprenyl diphosphate synthase component II; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: MFLO_04880
symbol: ndk
gene_biotype: protein_coding
description:
  Multifunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: MFLO_04885
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: MFLO_04905
symbol: EUJ32930.1
gene_biotype: protein_coding
description:
  Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.


ensembl_gene_id: MFLO_04910
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: MFLO_04920
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: MFLO_05015
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: MFLO_05020
symbol: cca
gene_biotype: protein_coding
description:
  tRNA CCA-pyrophosphorylase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.


ensembl_gene_id: MFLO_05025
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


ensembl_gene_id: MFLO_05050
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: MFLO_05055
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; COG0414 Panthothenate synthetase; Belongs to the pantothenate synthetase family.


ensembl_gene_id: MFLO_05065
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: MFLO_05095
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III (DNA repair); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: MFLO_05115
symbol: recU
gene_biotype: protein_coding
description:
  Holliday junction-specific endonuclease; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.


ensembl_gene_id: MFLO_05130
symbol: gpsB
gene_biotype: protein_coding
description:
  Hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.


ensembl_gene_id: MFLO_05140
symbol: EUJ32973.1
gene_biotype: protein_coding
description:
  Thermostable carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: MFLO_05145
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: MFLO_05155
symbol: rpsN-2
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: MFLO_05175
symbol: mntR
gene_biotype: protein_coding
description:
  Manganese transport transcriptional regulator; Central regulator of manganese homeostasis. Belongs to the DtxR/MntR family.


ensembl_gene_id: MFLO_05190
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: MFLO_05195
symbol: EUJ32984.1
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: MFLO_05230
symbol: EUJ32991.1
gene_biotype: protein_coding
description:
  Sodium-cystine symporter TcyP; COG1823 Predicted Na+/dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: MFLO_05290
symbol: msrA
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: MFLO_05295
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.


ensembl_gene_id: MFLO_05395
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: MFLO_05425
symbol: pyrR
gene_biotype: protein_coding
description:
  Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.


ensembl_gene_id: MFLO_05435
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: MFLO_05465
symbol: pyrK
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).


ensembl_gene_id: MFLO_05475
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: MFLO_05480
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: MFLO_05565
symbol: EUJ33040.1
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: MFLO_05580
symbol: rnj
gene_biotype: protein_coding
description:
  Ribonuclease J 1; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.


ensembl_gene_id: MFLO_05585
symbol: EUJ33042.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5503 Uncharacterized conserved small protein; Belongs to the UPF0356 family.


ensembl_gene_id: MFLO_05615
symbol: EUJ33048.1
gene_biotype: protein_coding
description:
  Putative molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: MFLO_05620
symbol: EUJ33049.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.


ensembl_gene_id: MFLO_05625
symbol: EUJ33050.1
gene_biotype: protein_coding
description:
  Putative molybdenum ABC transporter permease; COG4149 ABC-type molybdate transport system, permease component.


ensembl_gene_id: MFLO_05630
symbol: EUJ33051.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: MFLO_05660
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: MFLO_05670
symbol: moaA-2
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: MFLO_05675
symbol: EUJ33060.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_05680
symbol: EUJ33061.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: MFLO_05685
symbol: EUJ33062.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeB; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: MFLO_05690
symbol: EUJ33063.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: MFLO_05695
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: MFLO_05700
symbol: pdhA
gene_biotype: protein_coding
description:
  Putative pyruvate dehydrogenase (E1 subunit alpha); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: MFLO_05715
symbol: EUJ33066.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: MFLO_05720
symbol: EUJ33067.1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: MFLO_05750
symbol: EUJ33073.1
gene_biotype: protein_coding
description:
  Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: MFLO_05775
symbol: EUJ33078.1
gene_biotype: protein_coding
description:
  Cell cycle protein FtsW; COG0772 Bacterial cell division membrane protein; Belongs to the SEDS family.


ensembl_gene_id: MFLO_05785
symbol: EUJ33080.1
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: MFLO_05790
symbol: EUJ33081.1
gene_biotype: protein_coding
description:
  Teichoic acid translocation permease protein tagG; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: MFLO_05795
symbol: tagH
gene_biotype: protein_coding
description:
  Techoic acid ABC transporter ATP-binding protein; Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system.


ensembl_gene_id: MFLO_05839
symbol: EUJ32795.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein YclH; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: MFLO_05844
symbol: EUJ32796.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: MFLO_05854
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: MFLO_05869
symbol: EUJ32801.1
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: MFLO_05889
symbol: mltG
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: MFLO_05904
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: MFLO_05919
symbol: mtnN
gene_biotype: protein_coding
description:
  MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: MFLO_05944
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: MFLO_05954
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: MFLO_05964
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: MFLO_05974
symbol: EUJ32820.1
gene_biotype: protein_coding
description:
  Putative DNA internalization-related competence protein; COG1555 DNA uptake protein and related DNA-binding proteins.


ensembl_gene_id: MFLO_06049
symbol: sbcD
gene_biotype: protein_coding
description:
  Hypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: MFLO_06099
symbol: EUJ32839.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: MFLO_06104
symbol: EUJ32840.1
gene_biotype: protein_coding
description:
  Bacitracin ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: MFLO_06119
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: MFLO_06134
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: MFLO_06139
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: MFLO_06154
symbol: EUJ32848.1
gene_biotype: protein_coding
description:
  Putative transporter; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: MFLO_06169
symbol: nnrD
gene_biotype: protein_coding
description:
  ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.


ensembl_gene_id: MFLO_06174
symbol: EUJ32852.1
gene_biotype: protein_coding
description:
  MutT/NUDIX family hydrolase protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: MFLO_06179
symbol: EUJ32853.1
gene_biotype: protein_coding
description:
  Dipeptidase PepV; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: MFLO_06189
symbol: EUJ32855.1
gene_biotype: protein_coding
description:
  D-amino acid aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.


ensembl_gene_id: MFLO_06214
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: MFLO_06259
symbol: EUJ32869.1
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: MFLO_06284
symbol: menC
gene_biotype: protein_coding
description:
  N-acylamino acid racemase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: MFLO_06289
symbol: EUJ32699.1
gene_biotype: protein_coding
description:
  Teichoic acid biosynthesis protein A; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.


ensembl_gene_id: MFLO_06299
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: MFLO_06309
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: MFLO_06319
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: MFLO_06324
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: MFLO_06329
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: MFLO_06334
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: MFLO_06339
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: MFLO_06344
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: MFLO_06349
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: MFLO_06354
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: MFLO_06364
symbol: EUJ32714.1
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: MFLO_06379
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: MFLO_06384
symbol: EUJ32716.1
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine protein phosphatase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: MFLO_06389
symbol: EUJ32717.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: MFLO_06394
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: MFLO_06399
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: MFLO_06414
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: MFLO_06419
symbol: EUJ32723.1
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: MFLO_06449
symbol: mprF
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.


ensembl_gene_id: MFLO_06484
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: MFLO_06489
symbol: rpoE
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit delta; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family.


ensembl_gene_id: MFLO_06569
symbol: EUJ32747.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter substrate-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: MFLO_06609
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: MFLO_06634
symbol: EUJ32758.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: MFLO_06664
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: MFLO_06687
symbol: EUJ32397.1
gene_biotype: protein_coding
description:
  Putative HTH-type transcriptional regulator YulB; COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: MFLO_06702
symbol: EUJ32400.1
gene_biotype: protein_coding
description:
  General stress protein 13; COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain).


ensembl_gene_id: MFLO_06707
symbol: EUJ32401.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities.


ensembl_gene_id: MFLO_06742
symbol: EUJ32404.1
gene_biotype: protein_coding
description:
  Putative peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: MFLO_06752
symbol: EUJ32406.1
gene_biotype: protein_coding
description:
  Monovalent cation/H+ antiporter subunit A; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: MFLO_06827
symbol: EUJ32417.1
gene_biotype: protein_coding
description:
  PTS system lactose/cellobiose transporter subunit IIB; COG1440 Phosphotransferase system cellobiose-specific component IIB.


ensembl_gene_id: MFLO_06847
symbol: EUJ32419.1
gene_biotype: protein_coding
description:
  PTS system cellobiose-specific transporter subunit IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.


ensembl_gene_id: MFLO_06912
symbol: EUJ32432.1
gene_biotype: protein_coding
description:
  Ser/Thr protein phosphatase; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: MFLO_07032
symbol: EUJ32281.1
gene_biotype: protein_coding
description:
  Putative PTS system, fructose-specific enzyme IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: MFLO_07082
symbol: EUJ32291.1
gene_biotype: protein_coding
description:
  Putative transmembrane protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MFLO_07122
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: MFLO_07172
symbol: EUJ32305.1
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: MFLO_07197
symbol: EUJ32195.1
gene_biotype: protein_coding
description:
  D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.


ensembl_gene_id: MFLO_07202
symbol: EUJ32196.1
gene_biotype: protein_coding
description:
  D-alanine esterification of lipoteichoic acid and wall teichoic acid; Could be involved in the transport of activated D-alanine through the membrane.


ensembl_gene_id: MFLO_07207
symbol: dltA
gene_biotype: protein_coding
description:
  D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to  [...]


ensembl_gene_id: MFLO_07217
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: MFLO_07252
symbol: EUJ31969.1
gene_biotype: protein_coding
description:
  EmrB/QacA family drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: MFLO_07267
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: MFLO_07282
symbol: EUJ31973.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_07317
symbol: EUJ31980.1
gene_biotype: protein_coding
description:
  ATP-dependent protease; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: MFLO_07357
symbol: EUJ31988.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: MFLO_07382
symbol: EUJ31993.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: MFLO_07427
symbol: EUJ32002.1
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: MFLO_07442
symbol: nrdF
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: MFLO_07472
symbol: EUJ32011.1
gene_biotype: protein_coding
description:
  Iron compound ABC transporter substrate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: MFLO_07477
symbol: EUJ32012.1
gene_biotype: protein_coding
description:
  Transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: MFLO_07482
symbol: EUJ32013.1
gene_biotype: protein_coding
description:
  COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: MFLO_07502
symbol: EUJ32017.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4152 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: MFLO_07547
symbol: EUJ32026.1
gene_biotype: protein_coding
description:
  COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: MFLO_07607
symbol: EUJ32035.1
gene_biotype: protein_coding
description:
  COG1554 Trehalose and maltose hydrolases (possible phosphorylases); overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_07617
symbol: dacA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.


ensembl_gene_id: MFLO_07627
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: MFLO_07637
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: MFLO_07652
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: MFLO_07657
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: MFLO_07687
symbol: ctaA
gene_biotype: protein_coding
description:
  Cytochrome oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily.


ensembl_gene_id: MFLO_07692
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.


ensembl_gene_id: MFLO_07732
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: MFLO_07747
symbol: tmcAL
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.


ensembl_gene_id: MFLO_07767
symbol: EUJ32065.1
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; COG1893 Ketopantoate reductase; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_07782
symbol: mraZ
gene_biotype: protein_coding
description:
  Cell division protein MraZ; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: MFLO_07787
symbol: EUJ32069.1
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_07792
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: MFLO_07812
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: MFLO_07817
symbol: mraY
gene_biotype: protein_coding
description:
  COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: MFLO_07827
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: MFLO_07832
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: MFLO_07837
symbol: divIB
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.


ensembl_gene_id: MFLO_07842
symbol: EUJ32080.1
gene_biotype: protein_coding
description:
  COG0849 Actin-like ATPase involved in cell division; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_07847
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.


ensembl_gene_id: MFLO_07857
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: MFLO_07862
symbol: EUJ32084.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: MFLO_07867
symbol: sepF
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: MFLO_07877
symbol: EUJ32087.1
gene_biotype: protein_coding
description:
  Putative RNA-binding protein ylmH; COG2302 Uncharacterized conserved protein, contains S4-like domain.


ensembl_gene_id: MFLO_07912
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: MFLO_07917
symbol: EUJ32095.1
gene_biotype: protein_coding
description:
  Acid phosphatase/vanadium-dependent haloperoxidase family protein; COG0671 Membrane-associated phospholipid phosphatase.


ensembl_gene_id: MFLO_07927
symbol: EUJ32097.1
gene_biotype: protein_coding
description:
  Acetolactate synthase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: MFLO_07932
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: MFLO_07952
symbol: EUJ32100.1
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: MFLO_07982
symbol: EUJ32106.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster binding protein; COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain.


ensembl_gene_id: MFLO_07992
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: MFLO_07997
symbol: rnz
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: MFLO_08002
symbol: EUJ32110.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MFLO_08007
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: MFLO_08042
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: MFLO_08057
symbol: EUJ31749.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.


ensembl_gene_id: MFLO_08067
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: MFLO_08077
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: MFLO_08082
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: MFLO_08092
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: MFLO_08097
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: MFLO_08117
symbol: EUJ31761.1
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: MFLO_08172
symbol: EUJ31772.1
gene_biotype: protein_coding
description:
  General secretion pathway protein E; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: MFLO_08177
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: MFLO_08182
symbol: EUJ31774.1
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: MFLO_08192
symbol: gcvPB
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.


ensembl_gene_id: MFLO_08222
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: MFLO_08227
symbol: EUJ31783.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier family protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: MFLO_08247
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: MFLO_08252
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: MFLO_08267
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: MFLO_08272
symbol: EUJ31790.1
gene_biotype: protein_coding
description:
  Geranyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: MFLO_08282
symbol: EUJ31792.1
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: MFLO_08307
symbol: EUJ31797.1
gene_biotype: protein_coding
description:
  DNA repair and genetic recombination protein; May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: MFLO_08327
symbol: EUJ31801.1
gene_biotype: protein_coding
description:
  COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: MFLO_08332
symbol: EUJ31802.1
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase subunit beta; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: MFLO_08337
symbol: EUJ31803.1
gene_biotype: protein_coding
description:
  Putative branched-chain alpha-keto acid dehydrogenase; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: MFLO_08342
symbol: EUJ31804.1
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase complex subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: MFLO_08352
symbol: EUJ31806.1
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: MFLO_08372
symbol: yidC
gene_biotype: protein_coding
description:
  OxaA-like protein precursor; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.


ensembl_gene_id: MFLO_08417
symbol: EUJ31815.1
gene_biotype: protein_coding
description:
  COG0740 Protease subunit of ATP-dependent Clp proteases; overlaps another CDS with the same product name; Belongs to the peptidase S14 family.


ensembl_gene_id: MFLO_08422
symbol: EUJ31816.1
gene_biotype: protein_coding
description:
  COG0740 Protease subunit of ATP-dependent Clp proteases; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_08427
symbol: EUJ31817.1
gene_biotype: protein_coding
description:
  FtsK/SpoIIIE family protein; COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: MFLO_08437
symbol: EUJ31819.1
gene_biotype: protein_coding
description:
  CD4+ T cell-stimulating antigen, lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: MFLO_08442
symbol: EUJ31820.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter ATP-binding protein; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: MFLO_08447
symbol: EUJ31821.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MFLO_08452
symbol: EUJ31822.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MFLO_08467
symbol: EUJ31825.1
gene_biotype: protein_coding
description:
  3-ketoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_08482
symbol: EUJ31828.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: MFLO_08487
symbol: cinA
gene_biotype: protein_coding
description:
  Competence damage-inducible protein A; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.


ensembl_gene_id: MFLO_08492
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: MFLO_08517
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: MFLO_08522
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: MFLO_08527
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: MFLO_08532
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: MFLO_08547
symbol: secD
gene_biotype: protein_coding
description:
  Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: MFLO_08567
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: MFLO_08572
symbol: EUJ31846.1
gene_biotype: protein_coding
description:
  Putative (p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: MFLO_08577
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: MFLO_08592
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: MFLO_08632
symbol: EUJ31664.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: MFLO_08662
symbol: ulaD
gene_biotype: protein_coding
description:
  3-keto-L-gulonate-6-phosphate decarboxylase; COG0269 3-hexulose-6-phosphate synthase and related proteins.


ensembl_gene_id: MFLO_08667
symbol: EUJ31671.1
gene_biotype: protein_coding
description:
  PTS system ascorbate-specific transporter subunit IIA; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: MFLO_08672
symbol: EUJ31672.1
gene_biotype: protein_coding
description:
  PTS system ascorbate-specific transporter subunit IIB; COG3414 Phosphotransferase system, galactitol-specific IIB component.


ensembl_gene_id: MFLO_08677
symbol: EUJ31673.1
gene_biotype: protein_coding
description:
  PTS system ascorbate-specific transporter subunit IIC; COG3037 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: MFLO_08682
symbol: EUJ31674.1
gene_biotype: protein_coding
description:
  L-ascorbate 6-phosphate lactonase; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.


ensembl_gene_id: MFLO_08702
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]


ensembl_gene_id: MFLO_08722
symbol: EUJ31682.1
gene_biotype: protein_coding
description:
  RNase III inhibitor; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: MFLO_08737
symbol: EUJ31685.1
gene_biotype: protein_coding
description:
  COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: MFLO_08767
symbol: EUJ31509.1
gene_biotype: protein_coding
description:
  GCN5-like N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: MFLO_08827
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: MFLO_08862
symbol: EUJ31526.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: MFLO_08877
symbol: ppnK-2
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: MFLO_08882
symbol: EUJ31530.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: MFLO_08887
symbol: EUJ31531.1
gene_biotype: protein_coding
description:
  COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_08917
symbol: EUJ31334.1
gene_biotype: protein_coding
description:
  Sensor histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.


ensembl_gene_id: MFLO_08972
symbol: EUJ31343.1
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate galactosephosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.


ensembl_gene_id: MFLO_09032
symbol: EUJ31355.1
gene_biotype: protein_coding
description:
  Iron ABC transporter permease; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: MFLO_09037
symbol: EUJ31356.1
gene_biotype: protein_coding
description:
  Iron ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: MFLO_09042
symbol: EUJ31357.1
gene_biotype: protein_coding
description:
  Iron compound ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: MFLO_09052
symbol: EUJ31359.1
gene_biotype: protein_coding
description:
  Putative arsenate reductase with thioredoxin domain; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: MFLO_09062
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.


ensembl_gene_id: MFLO_09092
symbol: metN-2
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: MFLO_09102
symbol: EUJ31369.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.


ensembl_gene_id: MFLO_09107
symbol: EUJ31370.1
gene_biotype: protein_coding
description:
  Putative ABC transporter binding protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.


ensembl_gene_id: MFLO_09117
symbol: EUJ31372.1
gene_biotype: protein_coding
description:
  Lactose phosphotransferase system repressor; COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: MFLO_09127
symbol: EUJ31374.1
gene_biotype: protein_coding
description:
  Tagatose-6-phosphate kinase 2; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.


ensembl_gene_id: MFLO_09147
symbol: EUJ31378.1
gene_biotype: protein_coding
description:
  PTS family fructose/mannitol porter component IIA; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: MFLO_09152
symbol: EUJ31379.1
gene_biotype: protein_coding
description:
  PTS system transporter subunit IIB; COG3414 Phosphotransferase system, galactitol-specific IIB component.


ensembl_gene_id: MFLO_09157
symbol: EUJ31380.1
gene_biotype: protein_coding
description:
  PTS system galactitol (gat) transporter subunit IIC; COG3775 Phosphotransferase system, galactitol-specific IIC component.


ensembl_gene_id: MFLO_09172
symbol: EUJ31383.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.


ensembl_gene_id: MFLO_09177
symbol: EUJ31384.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: MFLO_09182
symbol: EUJ31385.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: MFLO_09192
symbol: EUJ31387.1
gene_biotype: protein_coding
description:
  FeS assembly protein SufB; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: MFLO_09277
symbol: EUJ31235.1
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: MFLO_09307
symbol: EUJ31239.1
gene_biotype: protein_coding
description:
  PTS system mannose family transporter subunit IID; COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID.


ensembl_gene_id: MFLO_09312
symbol: EUJ31240.1
gene_biotype: protein_coding
description:
  PTS system mannose-specific transporter subunit IIC; COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC.


ensembl_gene_id: MFLO_09317
symbol: EUJ31241.1
gene_biotype: protein_coding
description:
  PTS system mannost-specific transporter subunits IIAB; COG2893 Phosphotransferase system, mannose/fructose-specific component IIA.


ensembl_gene_id: MFLO_09327
symbol: EUJ31243.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: MFLO_09337
symbol: EUJ31245.1
gene_biotype: protein_coding
description:
  Iron-dependent alcohol dehydrogenase; COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family.


ensembl_gene_id: MFLO_09357
symbol: EUJ31249.1
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter ATP-binding protein; COG4604 ABC-type enterochelin transport system, ATPase component.


ensembl_gene_id: MFLO_09362
symbol: EUJ31250.1
gene_biotype: protein_coding
description:
  COG4605 ABC-type enterochelin transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: MFLO_09367
symbol: EUJ31251.1
gene_biotype: protein_coding
description:
  Transporter permease; COG4606 ABC-type enterochelin transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: MFLO_09417
symbol: EUJ31259.1
gene_biotype: protein_coding
description:
  Putative cryptic 6-phospho-beta-glucosidase, NAD(P)-binding protein; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: MFLO_09482
symbol: EUJ31269.1
gene_biotype: protein_coding
description:
  Diacetylchitobiose-6-phosphate hydrolase; COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases.


ensembl_gene_id: MFLO_09562
symbol: EUJ30932.1
gene_biotype: protein_coding
description:
  Gluconate kinase; COG1070 Sugar (pentulose and hexulose) kinases; Belongs to the FGGY kinase family.


ensembl_gene_id: MFLO_09567
symbol: EUJ30933.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP binding protein required for expression of cytochrome BD; COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.


ensembl_gene_id: MFLO_09572
symbol: EUJ30934.1
gene_biotype: protein_coding
description:
  Putative ABC transporter required for expression of cytochrome BD; COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.


ensembl_gene_id: MFLO_09582
symbol: EUJ30936.1
gene_biotype: protein_coding
description:
  COG1271 Cytochrome bd-type quinol oxidase, subunit 1; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_09592
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: MFLO_09662
symbol: EUJ30952.1
gene_biotype: protein_coding
description:
  UDP-glucose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: MFLO_09727
symbol: EUJ30965.1
gene_biotype: protein_coding
description:
  Teichoic acid/polysaccharide export protein; COG0728 Uncharacterized membrane protein, putative virulence factor; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_09742
symbol: EUJ30968.1
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthesis protein; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: MFLO_09852
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: MFLO_09882
symbol: EUJ30994.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: MFLO_09892
symbol: EUJ30996.1
gene_biotype: protein_coding
description:
  DHH subfamily 1 protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.


ensembl_gene_id: MFLO_09897
symbol: EUJ30997.1
gene_biotype: protein_coding
description:
  Putative 2-components response regulator protein; COG3279 Response regulator of the LytR/AlgR family.


ensembl_gene_id: MFLO_09902
symbol: EUJ30998.1
gene_biotype: protein_coding
description:
  Accessory gene regulator protein C; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.


ensembl_gene_id: MFLO_09907
symbol: EUJ30999.1
gene_biotype: protein_coding
description:
  Regulator; COG4512 Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide.


ensembl_gene_id: MFLO_09912
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: MFLO_09917
symbol: EUJ31001.1
gene_biotype: protein_coding
description:
  ssDNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: MFLO_09937
symbol: EUJ31005.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: MFLO_09967
symbol: EUJ31011.1
gene_biotype: protein_coding
description:
  PTS system beta-glucoside-specific transporter subunits IIABC; COG1264 Phosphotransferase system IIB components.


ensembl_gene_id: MFLO_09992
symbol: EUJ31016.1
gene_biotype: protein_coding
description:
  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: MFLO_09997
symbol: EUJ31017.1
gene_biotype: protein_coding
description:
  Putative quinol oxidase subunit II; Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I.


ensembl_gene_id: MFLO_10029
symbol: EUJ30732.1
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: MFLO_10034
symbol: EUJ30733.1
gene_biotype: protein_coding
description:
  Glutamine ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: MFLO_10069
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: MFLO_10074
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: MFLO_10099
symbol: EUJ30744.1
gene_biotype: protein_coding
description:
  PTS system iic component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.


ensembl_gene_id: MFLO_10104
symbol: EUJ30745.1
gene_biotype: protein_coding
description:
  aryl-phospho-beta-D-glucosidase BglC; COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: MFLO_10114
symbol: cshA
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily.


ensembl_gene_id: MFLO_10119
symbol: EUJ30748.1
gene_biotype: protein_coding
description:
  COG0076 Glutamate decarboxylase and related PLP-dependent proteins; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_10124
symbol: EUJ30749.1
gene_biotype: protein_coding
description:
  COG0076 Glutamate decarboxylase and related PLP-dependent proteins; overlaps another CDS with the same product name; Belongs to the group II decarboxylase family.


ensembl_gene_id: MFLO_10169
symbol: EUJ30758.1
gene_biotype: protein_coding
description:
  Cystine ABC transporter substrate-binding lipoprotein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: MFLO_10174
symbol: EUJ30759.1
gene_biotype: protein_coding
description:
  L-cystine import ABC transporter permease TcyB; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: MFLO_10179
symbol: EUJ30760.1
gene_biotype: protein_coding
description:
  Cystine ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: MFLO_10184
symbol: EUJ30761.1
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: MFLO_10189
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: MFLO_10204
symbol: EUJ30763.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain.


ensembl_gene_id: MFLO_10219
symbol: EUJ30766.1
gene_biotype: protein_coding
description:
  RsbT antagonist protein rsbS; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).


ensembl_gene_id: MFLO_10224
symbol: EUJ30767.1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase rsbT; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).


ensembl_gene_id: MFLO_10234
symbol: EUJ30769.1
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: MFLO_10239
symbol: rsbW
gene_biotype: protein_coding
description:
  Serine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).


ensembl_gene_id: MFLO_10244
symbol: EUJ30771.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: MFLO_10269
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: MFLO_10274
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: MFLO_10353
symbol: EUJ30655.1
gene_biotype: protein_coding
description:
  Putative pyruvate-flavodoxin oxidoreductase; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.


ensembl_gene_id: MFLO_10363
symbol: EUJ30657.1
gene_biotype: protein_coding
description:
  COG1455 Phosphotransferase system cellobiose-specific component IIC; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_10438
symbol: nanE
gene_biotype: protein_coding
description:
  N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).


ensembl_gene_id: MFLO_10488
symbol: EUJ30555.1
gene_biotype: protein_coding
description:
  COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: MFLO_10493
symbol: EUJ30556.1
gene_biotype: protein_coding
description:
  1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).


ensembl_gene_id: MFLO_10508
symbol: EUJ30557.1
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: MFLO_10518
symbol: EUJ30559.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter oligopeptide- binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: MFLO_10543
symbol: EUJ30256.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MFLO_10548
symbol: EUJ30257.1
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter ATP-binding protein; COG4608 ABC-type oligopeptide transport system, ATPase component.


ensembl_gene_id: MFLO_10553
symbol: EUJ30258.1
gene_biotype: protein_coding
description:
  COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MFLO_10558
symbol: spxA
gene_biotype: protein_coding
description:
  Transcriptional regulator Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.


ensembl_gene_id: MFLO_10563
symbol: mecA
gene_biotype: protein_coding
description:
  Adaptor protein; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.


ensembl_gene_id: MFLO_10668
symbol: EUJ30279.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_10803
symbol: EUJ30306.1
gene_biotype: protein_coding
description:
  Putative efflux ABC transporter, ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: MFLO_10808
symbol: EUJ30307.1
gene_biotype: protein_coding
description:
  Bacitracin transport permease BcrB; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: MFLO_10818
symbol: EUJ30309.1
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: MFLO_10833
symbol: EUJ30312.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: MFLO_10848
symbol: EUJ30315.1
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: MFLO_10883
symbol: EUJ30320.1
gene_biotype: protein_coding
description:
  MIP channel s family protein; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: MFLO_10898
symbol: EUJ30323.1
gene_biotype: protein_coding
description:
  Zinc-containing alcohol dehydrogenase superfamily protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: MFLO_10903
symbol: EUJ30324.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: MFLO_10950
symbol: EUJ29709.1
gene_biotype: protein_coding
description:
  Arsenical pump membrane protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.


ensembl_gene_id: MFLO_10975
symbol: EUJ29712.1
gene_biotype: protein_coding
description:
  Chitin binding domain-containing protein; COG3397 Uncharacterized protein conserved in bacteria; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_10980
symbol: EUJ29713.1
gene_biotype: protein_coding
description:
  COG3979 Uncharacterized protein contain chitin-binding domain type 3; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_11005
symbol: EUJ29716.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: MFLO_11030
symbol: EUJ29721.1
gene_biotype: protein_coding
description:
  Cytoplasmic protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: MFLO_11035
symbol: EUJ29118.1
gene_biotype: protein_coding
description:
  COG3557 Uncharacterized domain/protein associated with RNAses G and E; Belongs to the UPF0374 family.


ensembl_gene_id: MFLO_11040
symbol: EUJ29119.1
gene_biotype: protein_coding
description:
  Enoyl-(acyl carrier protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: MFLO_11055
symbol: EUJ29122.1
gene_biotype: protein_coding
description:
  dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.


ensembl_gene_id: MFLO_11085
symbol: EUJ29128.1
gene_biotype: protein_coding
description:
  Glycosyl transferase 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: MFLO_11120
symbol: EUJ29133.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.


ensembl_gene_id: MFLO_11155
symbol: EUJ29140.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: MFLO_11160
symbol: EUJ29141.1
gene_biotype: protein_coding
description:
  COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: MFLO_11200
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: MFLO_11255
symbol: EUJ29160.1
gene_biotype: protein_coding
description:
  Sigma-54 interaction domain-containing protein; COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain.


ensembl_gene_id: MFLO_11325
symbol: ade
gene_biotype: protein_coding
description:
  COG1001 Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: MFLO_11340
symbol: EUJ29177.1
gene_biotype: protein_coding
description:
  Sensory transduction protein BceR; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: MFLO_11370
symbol: EUJ29181.1
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance protein-like 2; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: MFLO_11375
symbol: EUJ29182.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase.


ensembl_gene_id: MFLO_11380
symbol: aroK
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: MFLO_11425
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: MFLO_11430
symbol: gatC
gene_biotype: protein_coding
description:
  asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: MFLO_11435
symbol: EUJ29192.1
gene_biotype: protein_coding
description:
  Phosphoesterase-related protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: MFLO_11450
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: MFLO_11465
symbol: EUJ29198.1
gene_biotype: protein_coding
description:
  Geranylgeranylglyceryl phosphate synthase-like protein; COG1646 Predicted phosphate-binding enzymes, TIM-barrel fold.


ensembl_gene_id: MFLO_11515
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: MFLO_11520
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: MFLO_11530
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: MFLO_11545
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: MFLO_11550
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought  [...]


ensembl_gene_id: MFLO_11555
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: MFLO_11565
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: MFLO_11570
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: MFLO_11599
symbol: EUJ28794.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: MFLO_11604
symbol: EUJ28795.1
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: MFLO_11609
symbol: EUJ28796.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: MFLO_11619
symbol: hslO
gene_biotype: protein_coding
description:
  Hsp33-like chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: MFLO_11624
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: MFLO_11629
symbol: ftsH
gene_biotype: protein_coding
description:
  Putative cell division protein ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: MFLO_11634
symbol: EUJ28801.1
gene_biotype: protein_coding
description:
  Bifunctional protein TilS/HprT; COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: MFLO_11664
symbol: EUJ28804.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).


ensembl_gene_id: MFLO_11669
symbol: EUJ28805.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis family protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: MFLO_11674
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: MFLO_11684
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: MFLO_11689
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: MFLO_11694
symbol: ldh
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.


ensembl_gene_id: MFLO_11699
symbol: ptcA
gene_biotype: protein_coding
description:
  Putrescine carbamoyltransferase; Catalyzes the phosphorolysis of N-carbamoylputrescine to form carbamoyl phosphate and putrescine. Is involved in the degradation pathway of the polyamine agmatine.


ensembl_gene_id: MFLO_11734
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: MFLO_11764
symbol: EUJ28824.1
gene_biotype: protein_coding
description:
  Pur operon repressor; COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.


ensembl_gene_id: MFLO_11789
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: MFLO_11794
symbol: rnmV
gene_biotype: protein_coding
description:
  Primase-like protein; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.


ensembl_gene_id: MFLO_11824
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.


ensembl_gene_id: MFLO_11834
symbol: rsmI
gene_biotype: protein_coding
description:
  Tetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: MFLO_11849
symbol: EUJ28836.1
gene_biotype: protein_coding
description:
  DNA replication initiation control protein YabA; Involved in initiation control of chromosome replication. Belongs to the YabA family.


ensembl_gene_id: MFLO_11869
symbol: EUJ28840.1
gene_biotype: protein_coding
description:
  STAS domain-containing protein; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).


ensembl_gene_id: MFLO_11884
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: MFLO_11964
symbol: tal
gene_biotype: protein_coding
description:
  Translaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: MFLO_12021
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: MFLO_12026
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: MFLO_12056
symbol: EUJ28479.1
gene_biotype: protein_coding
description:
  Legume lectin domain-containing protein; COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit.


ensembl_gene_id: MFLO_12116
symbol: EUJ28489.1
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes.


ensembl_gene_id: MFLO_12121
symbol: EUJ28490.1
gene_biotype: protein_coding
description:
  PTS modulated transcriptional regulator MtlR family protein; COG3711 Transcriptional antiterminator.


ensembl_gene_id: MFLO_12221
symbol: EUJ28506.1
gene_biotype: protein_coding
description:
  COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: MFLO_12246
symbol: EUJ28511.1
gene_biotype: protein_coding
description:
  Putative MutS family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: MFLO_12281
symbol: EUJ28518.1
gene_biotype: protein_coding
description:
  COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: MFLO_12291
symbol: EUJ28520.1
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: MFLO_12301
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: MFLO_12321
symbol: EUJ28524.1
gene_biotype: protein_coding
description:
  Family 1 extracellular solute-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: MFLO_12346
symbol: EUJ28529.1
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: MFLO_12376
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: MFLO_12406
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: MFLO_12426
symbol: EUJ28202.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: MFLO_12431
symbol: EUJ28203.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: MFLO_12436
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: MFLO_12446
symbol: rex
gene_biotype: protein_coding
description:
  Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: MFLO_12471
symbol: EUJ28211.1
gene_biotype: protein_coding
description:
  Lipoteichoic acid synthase-like yqgS; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Belongs to the LTA synthase family.


ensembl_gene_id: MFLO_12516
symbol: EUJ28220.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: MFLO_12591
symbol: EUJ28004.1
gene_biotype: protein_coding
description:
  Non-heme iron-binding ferritin; COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family.


ensembl_gene_id: MFLO_12611
symbol: EUJ28008.1
gene_biotype: protein_coding
description:
  Putative Nitroflavin-reductase; COG0778 Nitroreductase; Belongs to the flavin oxidoreductase frp family.


ensembl_gene_id: MFLO_12616
symbol: EUJ28009.1
gene_biotype: protein_coding
description:
  Putative CspR protein, rRNA methylase-like protein; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.


ensembl_gene_id: MFLO_12666
symbol: EUJ28016.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Belongs to the LTA synthase family.


ensembl_gene_id: MFLO_12671
symbol: EUJ28017.1
gene_biotype: protein_coding
description:
  Dicarboxylate/amino acid:cation (Na+ or H+) symporter; COG1301 Na+/H+-dicarboxylate symporters (DAACS) family protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: MFLO_12721
symbol: EUJ28025.1
gene_biotype: protein_coding
description:
  Acetyltransferase family protein; COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.


ensembl_gene_id: MFLO_12786
symbol: EUJ28038.1
gene_biotype: protein_coding
description:
  Glutathione reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: MFLO_12796
symbol: EUJ28040.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: MFLO_12846
symbol: EUJ28048.1
gene_biotype: protein_coding
description:
  DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: MFLO_12858
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: MFLO_12863
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: MFLO_12868
symbol: hpf
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: MFLO_12878
symbol: EUJ27928.1
gene_biotype: protein_coding
description:
  Putative late competence protein; COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).


ensembl_gene_id: MFLO_12883
symbol: EUJ27929.1
gene_biotype: protein_coding
description:
  Competence protein ComFA; COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein).


ensembl_gene_id: MFLO_12893
symbol: EUJ27931.1
gene_biotype: protein_coding
description:
  Putative two-component response regulator DegU; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: MFLO_12958
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: MFLO_12963
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: MFLO_12988
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: MFLO_12993
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: MFLO_13008
symbol: EUJ27389.1
gene_biotype: protein_coding
description:
  PTS system trehalose(maltose)-specific transporter subunits IIBC; COG1264 Phosphotransferase system IIB components; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_13013
symbol: EUJ27390.1
gene_biotype: protein_coding
description:
  PTS system trehalose(maltose)-specific transporter subunits IIBC; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_13063
symbol: EUJ27400.1
gene_biotype: protein_coding
description:
  Peptidoglycan binding protein, LysM domain protein; COG0739 Membrane proteins related to metalloendopeptidases.


ensembl_gene_id: MFLO_13093
symbol: EUJ27406.1
gene_biotype: protein_coding
description:
  Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: MFLO_13098
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: MFLO_13133
symbol: mutS2
gene_biotype: protein_coding
description:
  Recombination and DNA strand exchange inhibitor protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: MFLO_13148
symbol: EUJ27415.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: MFLO_13198
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: MFLO_13233
symbol: EUJ27428.1
gene_biotype: protein_coding
description:
  TrmH family RNA methyltransferase; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: MFLO_13288
symbol: EUJ27439.1
gene_biotype: protein_coding
description:
  Heat shock protein, Hsp20 family; COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: MFLO_13308
symbol: EUJ27441.1
gene_biotype: protein_coding
description:
  Putative CAAX amino terminal protease family protein; COG1266 Predicted metal-dependent membrane protease.


ensembl_gene_id: MFLO_13318
symbol: EUJ27443.1
gene_biotype: protein_coding
description:
  Microcin immunity protein; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.


ensembl_gene_id: MFLO_13363
symbol: EUJ27450.1
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; COG0406 Fructose-2,6-bisphosphatase; Belongs to the phosphoglycerate mutase family.


ensembl_gene_id: MFLO_13403
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: MFLO_13408
symbol: EUJ27459.1
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: MFLO_13418
symbol: EUJ27461.1
gene_biotype: protein_coding
description:
  Teichoic acid biosynthesis protein B; COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC.


ensembl_gene_id: MFLO_13423
symbol: tarJ
gene_biotype: protein_coding
description:
  Zinc-dependent alcohol dehydrogenase; Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: MFLO_13428
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the transfer of the cytidylyl group of CTP to D- ribitol 5-phosphate.


ensembl_gene_id: MFLO_13525
symbol: EUJ27191.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: MFLO_13530
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: MFLO_13560
symbol: EUJ27194.1
gene_biotype: protein_coding
description:
  PTS system mannnose-specific family transporter subunit IIA; COG3412 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: MFLO_13585
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: MFLO_13705
symbol: EUJ26931.1
gene_biotype: protein_coding
description:
  DNA polymerase IV 2; COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: MFLO_13905
symbol: EUJ26756.1
gene_biotype: protein_coding
description:
  4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: MFLO_13910
symbol: EUJ26757.1
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: MFLO_13920
symbol: EUJ26759.1
gene_biotype: protein_coding
description:
  2-hydroxymuconic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: MFLO_13960
symbol: mcsB
gene_biotype: protein_coding
description:
  ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family.


ensembl_gene_id: MFLO_13965
symbol: EUJ26580.1
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: MFLO_14047
symbol: EUJ26488.1
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: MFLO_14052
symbol: EUJ26489.1
gene_biotype: protein_coding
description:
  Carbon-sulfur lyase; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_14062
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: MFLO_14082
symbol: EUJ26495.1
gene_biotype: protein_coding
description:
  RecD/TraA family helicase; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_14107
symbol: EUJ26356.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: MFLO_14122
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: MFLO_14142
symbol: EUJ26363.1
gene_biotype: protein_coding
description:
  Heme-degrading monooxygenase IsdG; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: MFLO_14162
symbol: aroD
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.


ensembl_gene_id: MFLO_14167
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: MFLO_14172
symbol: EUJ26369.1
gene_biotype: protein_coding
description:
  Putative transcription regulatory protein AbrB; COG2002 Regulators of stationary/sporulation gene expression.


ensembl_gene_id: MFLO_14187
symbol: EUJ26116.1
gene_biotype: protein_coding
description:
  Molybdate ABC transporter substrate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: MFLO_14267
symbol: EUJ26126.1
gene_biotype: protein_coding
description:
  Capsular polysaccharide synthesis enzyme cap5O; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: MFLO_14297
symbol: EUJ26132.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: MFLO_14342
symbol: EUJ26141.1
gene_biotype: protein_coding
description:
  D-arabinose-proton symporter AraT; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: MFLO_14417
symbol: EUJ26156.1
gene_biotype: protein_coding
description:
  Bifunctional glutamate--cysteine ligase/glutathione synthetase; COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family.


ensembl_gene_id: MFLO_14427
symbol: EUJ26158.1
gene_biotype: protein_coding
description:
  Bifunctional glutamate--cysteine ligase/glutathione synthetase; COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes.


ensembl_gene_id: MFLO_14432
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: MFLO_14447
symbol: EUJ26162.1
gene_biotype: protein_coding
description:
  ParB family chromosome partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: MFLO_14472
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 535 of 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: MFLO_14477
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: MFLO_14482
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: MFLO_14492
symbol: EUJ26171.1
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: MFLO_14497
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: MFLO_14537
symbol: EUJ25981.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: MFLO_14557
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: MFLO_14577
symbol: EUJ25985.1
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: MFLO_14602
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: MFLO_14607
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: MFLO_14672
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: MFLO_14677
symbol: EUJ25863.1
gene_biotype: protein_coding
description:
  Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family.


ensembl_gene_id: MFLO_14687
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: MFLO_14823
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: MFLO_14828
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: MFLO_14833
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: MFLO_14838
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: MFLO_14843
symbol: EUJ25710.1
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: MFLO_14848
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: MFLO_14858
symbol: EUJ25713.1
gene_biotype: protein_coding
description:
  Putative acetolactate synthase large subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: MFLO_14883
symbol: EUJ25718.1
gene_biotype: protein_coding
description:
  Adhesion lipoprotein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: MFLO_14888
symbol: EUJ25719.1
gene_biotype: protein_coding
description:
  Manganese ABC transporter inner membrane permease SitD; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.


ensembl_gene_id: MFLO_14893
symbol: EUJ25720.1
gene_biotype: protein_coding
description:
  Putative manganese ABC transporter ATP-binding protein; COG1121 ABC-type Mn/Zn transport systems, ATPase component.


ensembl_gene_id: MFLO_14918
symbol: EUJ25725.1
gene_biotype: protein_coding
description:
  hydroxymethylglutaryl-CoA reductase, degradative; COG1257 Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.


ensembl_gene_id: MFLO_14923
symbol: EUJ25726.1
gene_biotype: protein_coding
description:
  COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta); overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_14933
symbol: EUJ25728.1
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: MFLO_14948
symbol: EUJ25731.1
gene_biotype: protein_coding
description:
  Oxidoreductase, aldo/keto reductase family protein; COG0656 Aldo/keto reductases, related to diketogulonate reductase.


ensembl_gene_id: MFLO_14963
symbol: EUJ25734.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit.


ensembl_gene_id: MFLO_15032
symbol: EUJ25651.1
gene_biotype: protein_coding
description:
  Thioredoxin 1; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.


ensembl_gene_id: MFLO_15054
symbol: EUJ25566.1
gene_biotype: protein_coding
description:
  Cell division ABC transporter permease; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: MFLO_15079
symbol: EUJ25571.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: MFLO_15089
symbol: EUJ25573.1
gene_biotype: protein_coding
description:
  Putative two-component response phosphate regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: MFLO_15099
symbol: EUJ25575.1
gene_biotype: protein_coding
description:
  Putative phosphate ABC transporter binding protein; COG0226 ABC-type phosphate transport system, periplasmic component.


ensembl_gene_id: MFLO_15104
symbol: EUJ25576.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: MFLO_15114
symbol: EUJ25578.1
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; COG1117 ABC-type phosphate transport system, ATPase component; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_15119
symbol: EUJ25579.1
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; COG1117 ABC-type phosphate transport system, ATPase component; overlaps another CDS with the same product name; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MFLO_15129
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: MFLO_15179
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: MFLO_15189
symbol: uvrA-2
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: MFLO_15224
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: MFLO_15229
symbol: ppaX
gene_biotype: protein_coding
description:
  Pyrophosphatase PpaX; Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.


ensembl_gene_id: MFLO_15274
symbol: EUJ25608.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: MFLO_15299
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: MFLO_15319
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: MFLO_15324
symbol: cas2
gene_biotype: protein_coding
description:
  CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette; Belongs to the CRISPR-associated endoribonucleas [...]


ensembl_gene_id: MFLO_15416
symbol: EUJ25463.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: MFLO_15426
symbol: EUJ25465.1
gene_biotype: protein_coding
description:
  Putative Fur family transcriptional regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: MFLO_15433
symbol: EUJ25384.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: MFLO_15438
symbol: EUJ25385.1
gene_biotype: protein_coding
description:
  COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_15463
symbol: EUJ25390.1
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: MFLO_15498
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: MFLO_15503
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: MFLO_15508
symbol: EUJ25397.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: MFLO_15825
symbol: EUJ23738.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; overlaps another CDS with the same product name.


ensembl_gene_id: MFLO_15830
symbol: EUJ23739.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; overlaps another CDS with the same product name; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


