# geneInfo

ensembl_gene_id: GCA_000425805_00004
symbol: BHU25_08595
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: GCA_000425805_00011
symbol: kdpA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: GCA_000425805_00012
symbol: kdpB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: GCA_000425805_00013
symbol: kdpC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: GCA_000425805_00023
symbol: BHU25_08685
gene_biotype: protein_coding
description:
  Unannotated protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: GCA_000425805_00026
symbol: greB
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: GCA_000425805_00035
symbol: BHU25_08740
gene_biotype: protein_coding
description:
  Unannotated protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: GCA_000425805_00048
symbol: prpB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: GCA_000425805_00060
symbol: lpxH
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_000425805_00061
symbol: BHU25_08900
gene_biotype: protein_coding
description:
  Unannotated protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: GCA_000425805_00086
symbol: katG
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: GCA_000425805_00096
symbol: BHU25_08230
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: GCA_000425805_00208
symbol: BHU25_22105
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: GCA_000425805_00275
symbol: BHU25_09255
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).


ensembl_gene_id: GCA_000425805_00295
symbol: rbsK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: GCA_000425805_00303
symbol: thrS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: GCA_000425805_00304
symbol: infC
gene_biotype: protein_coding
description:
  Unannotated protein; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: GCA_000425805_00306
symbol: rplT
gene_biotype: protein_coding
description:
  Unannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: GCA_000425805_00307
symbol: pheS
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: GCA_000425805_00308
symbol: pheT
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: GCA_000425805_00309
symbol: ihfA
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: GCA_000425805_00328
symbol: BHU25_13445
gene_biotype: protein_coding
description:
  Unannotated protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.


ensembl_gene_id: GCA_000425805_00353
symbol: sotB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: GCA_000425805_00363
symbol: BHU25_13280
gene_biotype: protein_coding
description:
  Unannotated protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: GCA_000425805_00383
symbol: BHU25_16575
gene_biotype: protein_coding
description:
  Unannotated protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: GCA_000425805_00386
symbol: moaA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: GCA_000425805_00526
symbol: csrA
gene_biotype: protein_coding
description:
  Unannotated protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: GCA_000425805_00528
symbol: modC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: GCA_000425805_00529
symbol: BHU25_23590
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: GCA_000425805_00540
symbol: BHU25_23635
gene_biotype: protein_coding
description:
  Unannotated protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: GCA_000425805_00554
symbol: aroQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: GCA_000425805_00564
symbol: BHU25_18000
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: GCA_000425805_00578
symbol: glgE
gene_biotype: protein_coding
description:
  Unannotated protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: GCA_000425805_00580
symbol: glgB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: GCA_000425805_00594
symbol: nhaB
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: GCA_000425805_00609
symbol: BHU25_12125
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: GCA_000425805_00612
symbol: nfuA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: GCA_000425805_00622
symbol: ureD
gene_biotype: protein_coding
description:
  Unannotated protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: GCA_000425805_00626
symbol: ureE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: GCA_000425805_00629
symbol: ureG
gene_biotype: protein_coding
description:
  Unannotated protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: GCA_000425805_00663
symbol: tpx
gene_biotype: protein_coding
description:
  Unannotated protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: GCA_000425805_00671
symbol: hutG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: GCA_000425805_00672
symbol: gltS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: GCA_000425805_00687
symbol: BHU25_13800
gene_biotype: protein_coding
description:
  Unannotated protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: GCA_000425805_00715
symbol: ku
gene_biotype: protein_coding
description:
  Unannotated protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: GCA_000425805_00725
symbol: fusA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: GCA_000425805_00788
symbol: tyrS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: GCA_000425805_00790
symbol: anmK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: GCA_000425805_00792
symbol: argC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: GCA_000425805_00797
symbol: coq7
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: GCA_000425805_00803
symbol: trpD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: GCA_000425805_00805
symbol: trpE
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.


ensembl_gene_id: GCA_000425805_00806
symbol: BHU25_07970
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: GCA_000425805_00811
symbol: potA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_000425805_00818
symbol: lptD
gene_biotype: protein_coding
description:
  Unannotated protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: GCA_000425805_00819
symbol: surA
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: GCA_000425805_00820
symbol: pdxA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: GCA_000425805_00821
symbol: rsmA
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: GCA_000425805_00823
symbol: apaH
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: GCA_000425805_00824
symbol: glpE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: GCA_000425805_00828
symbol: cca
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: GCA_000425805_00830
symbol: BHU25_07850
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: GCA_000425805_00831
symbol: plsY
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: GCA_000425805_00832
symbol: tsaD
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: GCA_000425805_00834
symbol: dnaG
gene_biotype: protein_coding
description:
  Unannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: GCA_000425805_00835
symbol: rpoD
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: GCA_000425805_00842
symbol: panB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: GCA_000425805_00847
symbol: pqqB
gene_biotype: protein_coding
description:
  Unannotated protein; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: GCA_000425805_00848
symbol: pqqC
gene_biotype: protein_coding
description:
  Unannotated protein; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: GCA_000425805_00849
symbol: pqqD
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.


ensembl_gene_id: GCA_000425805_00850
symbol: pqqE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: GCA_000425805_00859
symbol: bioD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: GCA_000425805_00860
symbol: bioC
gene_biotype: protein_coding
description:
  Unannotated protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: GCA_000425805_00862
symbol: bioF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: GCA_000425805_00863
symbol: bioB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: GCA_000425805_00867
symbol: srkA
gene_biotype: protein_coding
description:
  Unannotated protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: GCA_000425805_00870
symbol: glcB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: GCA_000425805_00882
symbol: BHU25_07595
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.


ensembl_gene_id: GCA_000425805_00886
symbol: glnE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) [...]


ensembl_gene_id: GCA_000425805_00887
symbol: BHU25_07570
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: GCA_000425805_00888
symbol: BHU25_07565
gene_biotype: protein_coding
description:
  Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: GCA_000425805_00890
symbol: msrA
gene_biotype: protein_coding
description:
  Unannotated protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: GCA_000425805_00901
symbol: purU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: GCA_000425805_00906
symbol: glyA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: GCA_000425805_00907
symbol: BHU25_07450
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: GCA_000425805_00928
symbol: lcdH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.


ensembl_gene_id: GCA_000425805_00936
symbol: hisF
gene_biotype: protein_coding
description:
  Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: GCA_000425805_00939
symbol: hisH
gene_biotype: protein_coding
description:
  Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: GCA_000425805_00945
symbol: BHU25_07255
gene_biotype: protein_coding
description:
  Unannotated protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: GCA_000425805_00960
symbol: hldD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: GCA_000425805_00965
symbol: aguA
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.


ensembl_gene_id: GCA_000425805_00968
symbol: BHU25_06935
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: GCA_000425805_00969
symbol: BHU25_06930
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: GCA_000425805_00971
symbol: BHU25_06920
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: GCA_000425805_00975
symbol: cysQ
gene_biotype: protein_coding
description:
  Unannotated protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: GCA_000425805_00980
symbol: fdhD
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: GCA_000425805_00984
symbol: pckA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: GCA_000425805_00985
symbol: hslO
gene_biotype: protein_coding
description:
  Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: GCA_000425805_00996
symbol: ssuB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_000425805_00998
symbol: ssuD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: GCA_000425805_01004
symbol: tauB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: GCA_000425805_01017
symbol: metN
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_000425805_01038
symbol: gcvP
gene_biotype: protein_coding
description:
  Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: GCA_000425805_01039
symbol: gcvH
gene_biotype: protein_coding
description:
  Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: GCA_000425805_01049
symbol: BHU25_17670
gene_biotype: protein_coding
description:
  Unannotated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: GCA_000425805_01056
symbol: BHU25_17705
gene_biotype: protein_coding
description:
  Unannotated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: GCA_000425805_01059
symbol: BHU25_17715
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: GCA_000425805_01061
symbol: ubiD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: GCA_000425805_01062
symbol: rho
gene_biotype: protein_coding
description:
  Unannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: GCA_000425805_01065
symbol: ppk
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: GCA_000425805_01069
symbol: BHU25_17760
gene_biotype: protein_coding
description:
  Unannotated protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: GCA_000425805_01083
symbol: hemC
gene_biotype: protein_coding
description:
  Unannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: GCA_000425805_01092
symbol: cyaY
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: GCA_000425805_01094
symbol: lysA
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: GCA_000425805_01095
symbol: dapF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: GCA_000425805_01097
symbol: xerC
gene_biotype: protein_coding
description:
  Unannotated protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: GCA_000425805_01117
symbol: rep
gene_biotype: protein_coding
description:
  Unannotated protein; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: GCA_000425805_01118
symbol: xpt
gene_biotype: protein_coding
description:
  Unannotated protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: GCA_000425805_01122
symbol: BHU25_18075
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: GCA_000425805_01138
symbol: BHU25_18160
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: GCA_000425805_01139
symbol: dut
gene_biotype: protein_coding
description:
  Unannotated protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: GCA_000425805_01141
symbol: argB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: GCA_000425805_01142
symbol: pyrE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: GCA_000425805_01145
symbol: rph
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: GCA_000425805_01153
symbol: rpoZ
gene_biotype: protein_coding
description:
  Unannotated protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: GCA_000425805_01154
symbol: BHU25_18245
gene_biotype: protein_coding
description:
  Unannotated protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: GCA_000425805_01162
symbol: recG
gene_biotype: protein_coding
description:
  Unannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: GCA_000425805_01165
symbol: BHU25_18330
gene_biotype: protein_coding
description:
  Unannotated protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: GCA_000425805_01168
symbol: ubiC
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: GCA_000425805_01169
symbol: ubiA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: GCA_000425805_01177
symbol: pstB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: GCA_000425805_01187
symbol: purK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: GCA_000425805_01188
symbol: purE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: GCA_000425805_01211
symbol: pdxY
gene_biotype: protein_coding
description:
  Unannotated protein; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: GCA_000425805_01218
symbol: clsA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: GCA_000425805_01235
symbol: glmS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: GCA_000425805_01237
symbol: glmU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: GCA_000425805_01238
symbol: atpC
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: GCA_000425805_01239
symbol: atpD
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: GCA_000425805_01240
symbol: atpG
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: GCA_000425805_01241
symbol: atpA
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: GCA_000425805_01242
symbol: atpH
gene_biotype: protein_coding
description:
  Unannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: GCA_000425805_01243
symbol: atpF
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: GCA_000425805_01245
symbol: atpB
gene_biotype: protein_coding
description:
  Unannotated protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: GCA_000425805_01249
symbol: rsmG
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: GCA_000425805_01250
symbol: mnmG
gene_biotype: protein_coding
description:
  Unannotated protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: GCA_000425805_01251
symbol: mnmE
gene_biotype: protein_coding
description:
  Unannotated protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: GCA_000425805_01252
symbol: yidC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: GCA_000425805_01255
symbol: dnaA
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: GCA_000425805_01256
symbol: BHU25_18745
gene_biotype: protein_coding
description:
  Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication  [...]


ensembl_gene_id: GCA_000425805_01257
symbol: recF
gene_biotype: protein_coding
description:
  Unannotated protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: GCA_000425805_01258
symbol: gyrB
gene_biotype: protein_coding
description:
  Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: GCA_000425805_01288
symbol: fmt
gene_biotype: protein_coding
description:
  Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: GCA_000425805_01289
symbol: def
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: GCA_000425805_01291
symbol: tsaC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: GCA_000425805_01293
symbol: hemF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: GCA_000425805_01294
symbol: aroE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: GCA_000425805_01301
symbol: trpA
gene_biotype: protein_coding
description:
  Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: GCA_000425805_01302
symbol: trpB
gene_biotype: protein_coding
description:
  Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: GCA_000425805_01318
symbol: BHU25_18985
gene_biotype: protein_coding
description:
  Unannotated protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: GCA_000425805_01321
symbol: BHU25_19000
gene_biotype: protein_coding
description:
  Unannotated protein; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: GCA_000425805_01322
symbol: BHU25_19005
gene_biotype: protein_coding
description:
  Unannotated protein; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: GCA_000425805_01329
symbol: cyoE
gene_biotype: protein_coding
description:
  Unannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: GCA_000425805_01337
symbol: znuC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: GCA_000425805_01342
symbol: polA
gene_biotype: protein_coding
description:
  Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: GCA_000425805_01343
symbol: engB
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: GCA_000425805_01357
symbol: gltP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.


ensembl_gene_id: GCA_000425805_01375
symbol: BHU25_19295
gene_biotype: protein_coding
description:
  Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: GCA_000425805_01388
symbol: cysZ
gene_biotype: protein_coding
description:
  Unannotated protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: GCA_000425805_01396
symbol: fabV
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: GCA_000425805_01415
symbol: hmgA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: GCA_000425805_01421
symbol: dsbB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: GCA_000425805_01436
symbol: selU
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: GCA_000425805_01439
symbol: phnC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: GCA_000425805_01450
symbol: BHU25_00540
gene_biotype: protein_coding
description:
  Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: GCA_000425805_01452
symbol: queA
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: GCA_000425805_01453
symbol: tgt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  [...]


ensembl_gene_id: GCA_000425805_01454
symbol: yajC
gene_biotype: protein_coding
description:
  Unannotated protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: GCA_000425805_01455
symbol: secD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: GCA_000425805_01459
symbol: trmJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: GCA_000425805_01461
symbol: BHU25_00480
gene_biotype: protein_coding
description:
  Unannotated protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: GCA_000425805_01462
symbol: iscS
gene_biotype: protein_coding
description:
  Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: GCA_000425805_01463
symbol: BHU25_00470
gene_biotype: protein_coding
description:
  Unannotated protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: GCA_000425805_01464
symbol: BHU25_00465
gene_biotype: protein_coding
description:
  Unannotated protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: GCA_000425805_01465
symbol: hscB
gene_biotype: protein_coding
description:
  Unannotated protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: GCA_000425805_01466
symbol: hscA
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: GCA_000425805_01469
symbol: ndk
gene_biotype: protein_coding
description:
  Unannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: GCA_000425805_01470
symbol: rlmN
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: GCA_000425805_01473
symbol: ispG
gene_biotype: protein_coding
description:
  Unannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: GCA_000425805_01476
symbol: bamB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: GCA_000425805_01477
symbol: der
gene_biotype: protein_coding
description:
  Unannotated protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: GCA_000425805_01493
symbol: prfC
gene_biotype: protein_coding
description:
  Unannotated protein; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: GCA_000425805_01513
symbol: rlpA
gene_biotype: protein_coding
description:
  Unannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: GCA_000425805_01514
symbol: gatB
gene_biotype: protein_coding
description:
  Unannotated protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: GCA_000425805_01515
symbol: gatA
gene_biotype: protein_coding
description:
  Unannotated protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: GCA_000425805_01516
symbol: gatC
gene_biotype: protein_coding
description:
  Unannotated protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: GCA_000425805_01519
symbol: BHU25_00005
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: GCA_000425805_01520
symbol: BHU25_00010
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: GCA_000425805_01528
symbol: aspA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: GCA_000425805_01530
symbol: BHU25_00060
gene_biotype: protein_coding
description:
  Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: GCA_000425805_01536
symbol: BHU25_00090
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: GCA_000425805_01538
symbol: lptA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: GCA_000425805_01539
symbol: lptC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.


ensembl_gene_id: GCA_000425805_01540
symbol: BHU25_00110
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: GCA_000425805_01549
symbol: murA
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: GCA_000425805_01550
symbol: hisG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: GCA_000425805_01551
symbol: hisD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: GCA_000425805_01552
symbol: hisC
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: GCA_000425805_01560
symbol: valS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: GCA_000425805_01563
symbol: pepA
gene_biotype: protein_coding
description:
  Unannotated protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: GCA_000425805_01575
symbol: BHU25_09865
gene_biotype: protein_coding
description:
  Unannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: GCA_000425805_01585
symbol: edd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: GCA_000425805_01599
symbol: leuA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: GCA_000425805_01601
symbol: xseA
gene_biotype: protein_coding
description:
  Unannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: GCA_000425805_01605
symbol: guaB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: GCA_000425805_01608
symbol: tadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: GCA_000425805_01609
symbol: mltF
gene_biotype: protein_coding
description:
  Unannotated protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: GCA_000425805_01610
symbol: purL
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: GCA_000425805_01620
symbol: purT
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: GCA_000425805_01624
symbol: ffh
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to t [...]


ensembl_gene_id: GCA_000425805_01626
symbol: rimM
gene_biotype: protein_coding
description:
  Unannotated protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: GCA_000425805_01627
symbol: trmD
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: GCA_000425805_01628
symbol: rplS
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: GCA_000425805_01630
symbol: BHU25_10315
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: GCA_000425805_01632
symbol: BHU25_10325
gene_biotype: protein_coding
description:
  Unannotated protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: GCA_000425805_01655
symbol: cheB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: GCA_000425805_01657
symbol: prfB
gene_biotype: protein_coding
description:
  Unannotated protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: GCA_000425805_01667
symbol: ppc
gene_biotype: protein_coding
description:
  Unannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: GCA_000425805_01668
symbol: adk
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: GCA_000425805_01685
symbol: dapE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: GCA_000425805_01690
symbol: dapD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: GCA_000425805_01692
symbol: BHU25_10640
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: GCA_000425805_01694
symbol: glnD
gene_biotype: protein_coding
description:
  Unannotated protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: GCA_000425805_01695
symbol: map
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: GCA_000425805_01697
symbol: tsf
gene_biotype: protein_coding
description:
  Unannotated protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: GCA_000425805_01699
symbol: frr
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: GCA_000425805_01700
symbol: uppS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: GCA_000425805_01702
symbol: dxr
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: GCA_000425805_01706
symbol: lpxD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: GCA_000425805_01707
symbol: fabZ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: GCA_000425805_01708
symbol: lpxA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_000425805_01709
symbol: lpxB
gene_biotype: protein_coding
description:
  Unannotated protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_000425805_01712
symbol: accA
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: GCA_000425805_01714
symbol: pyrG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: GCA_000425805_01716
symbol: eno
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: GCA_000425805_01717
symbol: ftsB
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: GCA_000425805_01718
symbol: ispD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: GCA_000425805_01722
symbol: ispF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: GCA_000425805_01723
symbol: truD
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: GCA_000425805_01724
symbol: surE
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: GCA_000425805_01725
symbol: pcm
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: GCA_000425805_01727
symbol: rpoS
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: GCA_000425805_01728
symbol: BHU25_10820
gene_biotype: protein_coding
description:
  Unannotated protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: GCA_000425805_01729
symbol: mutS
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: GCA_000425805_01751
symbol: recA
gene_biotype: protein_coding
description:
  Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: GCA_000425805_01758
symbol: BHU25_11000
gene_biotype: protein_coding
description:
  Unannotated protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: GCA_000425805_01765
symbol: rimO
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: GCA_000425805_01766
symbol: kup
gene_biotype: protein_coding
description:
  Unannotated protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: GCA_000425805_01771
symbol: dinB
gene_biotype: protein_coding
description:
  Unannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: GCA_000425805_01773
symbol: proS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyl [...]


ensembl_gene_id: GCA_000425805_01781
symbol: aspS
gene_biotype: protein_coding
description:
  Unannotated protein; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: GCA_000425805_01783
symbol: ruvC
gene_biotype: protein_coding
description:
  Unannotated protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: GCA_000425805_01784
symbol: ruvA
gene_biotype: protein_coding
description:
  Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: GCA_000425805_01785
symbol: ruvB
gene_biotype: protein_coding
description:
  Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: GCA_000425805_01787
symbol: tolQ
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: GCA_000425805_01792
symbol: cpoB
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: GCA_000425805_01793
symbol: queE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: GCA_000425805_01794
symbol: queC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: GCA_000425805_01816
symbol: BHU25_11250
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.


ensembl_gene_id: GCA_000425805_01818
symbol: nadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: GCA_000425805_01819
symbol: BHU25_11265
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: GCA_000425805_01824
symbol: dapA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: GCA_000425805_01843
symbol: rnd
gene_biotype: protein_coding
description:
  Unannotated protein; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: GCA_000425805_01859
symbol: BHU25_11490
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: GCA_000425805_01869
symbol: aceK
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: GCA_000425805_01908
symbol: azoR
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: GCA_000425805_01955
symbol: algL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism; Belongs to the polysaccharide lyase 5 family.


ensembl_gene_id: GCA_000425805_01970
symbol: moaC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: GCA_000425805_01977
symbol: rhlB
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: GCA_000425805_01986
symbol: cysN
gene_biotype: protein_coding
description:
  Unannotated protein; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: GCA_000425805_01992
symbol: trpS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: GCA_000425805_01996
symbol: rplM
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: GCA_000425805_01998
symbol: BHU25_14955
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: GCA_000425805_02005
symbol: gmhA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: GCA_000425805_02008
symbol: rsmI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: GCA_000425805_02010
symbol: rsmH
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: GCA_000425805_02013
symbol: murE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: GCA_000425805_02014
symbol: murF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: GCA_000425805_02015
symbol: mraY
gene_biotype: protein_coding
description:
  Unannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: GCA_000425805_02016
symbol: murD
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: GCA_000425805_02017
symbol: ftsW
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: GCA_000425805_02018
symbol: murG
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: GCA_000425805_02021
symbol: ftsQ
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: GCA_000425805_02022
symbol: ftsA
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: GCA_000425805_02023
symbol: ftsZ
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: GCA_000425805_02024
symbol: lpxC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: GCA_000425805_02026
symbol: secA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: GCA_000425805_02027
symbol: argJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: GCA_000425805_02041
symbol: groS
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: GCA_000425805_02042
symbol: groL
gene_biotype: protein_coding
description:
  Unannotated protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: GCA_000425805_02072
symbol: BHU25_14580
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: GCA_000425805_02145
symbol: ung
gene_biotype: protein_coding
description:
  Unannotated protein; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: GCA_000425805_02162
symbol: lepA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: GCA_000425805_02164
symbol: rnc
gene_biotype: protein_coding
description:
  Unannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: GCA_000425805_02165
symbol: era
gene_biotype: protein_coding
description:
  Unannotated protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: GCA_000425805_02167
symbol: pdxJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: GCA_000425805_02175
symbol: cmoB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: GCA_000425805_02176
symbol: cmoA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: GCA_000425805_02178
symbol: lon
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: GCA_000425805_02193
symbol: metE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: GCA_000425805_02205
symbol: glpK
gene_biotype: protein_coding
description:
  Unannotated protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: GCA_000425805_02212
symbol: BHU25_02060
gene_biotype: protein_coding
description:
  Unannotated protein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: GCA_000425805_02215
symbol: rnt
gene_biotype: protein_coding
description:
  Unannotated protein; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: GCA_000425805_02222
symbol: nth
gene_biotype: protein_coding
description:
  Unannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: GCA_000425805_02225
symbol: rnfD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: GCA_000425805_02226
symbol: BHU25_01995
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: GCA_000425805_02228
symbol: metG
gene_biotype: protein_coding
description:
  Unannotated protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: GCA_000425805_02229
symbol: BHU25_01980
gene_biotype: protein_coding
description:
  Unannotated protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: GCA_000425805_02249
symbol: pdxH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: GCA_000425805_02252
symbol: nhaA
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: GCA_000425805_02268
symbol: rapA
gene_biotype: protein_coding
description:
  Unannotated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: GCA_000425805_02361
symbol: BHU25_17340
gene_biotype: protein_coding
description:
  Unannotated protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: GCA_000425805_02362
symbol: napA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: GCA_000425805_02363
symbol: napD
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: GCA_000425805_02406
symbol: BHU25_16010
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family.


ensembl_gene_id: GCA_000425805_02448
symbol: uppP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: GCA_000425805_02612
symbol: phnW
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.


ensembl_gene_id: GCA_000425805_02613
symbol: phnX
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.


ensembl_gene_id: GCA_000425805_02619
symbol: dnaQ
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: GCA_000425805_02622
symbol: gloB
gene_biotype: protein_coding
description:
  Unannotated protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: GCA_000425805_02632
symbol: clpX
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: GCA_000425805_02633
symbol: clpP
gene_biotype: protein_coding
description:
  Unannotated protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: GCA_000425805_02634
symbol: tig
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: GCA_000425805_02639
symbol: BHU25_25690
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: GCA_000425805_02647
symbol: folD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: GCA_000425805_02672
symbol: fabA
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: GCA_000425805_02685
symbol: sucD
gene_biotype: protein_coding
description:
  Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: GCA_000425805_02686
symbol: sucC
gene_biotype: protein_coding
description:
  Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: GCA_000425805_02688
symbol: BHU25_25415
gene_biotype: protein_coding
description:
  Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: GCA_000425805_02709
symbol: macB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: GCA_000425805_02713
symbol: dsbD
gene_biotype: protein_coding
description:
  Unannotated protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: GCA_000425805_02718
symbol: ppnP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: GCA_000425805_02735
symbol: apt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: GCA_000425805_02736
symbol: recR
gene_biotype: protein_coding
description:
  Unannotated protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: GCA_000425805_02737
symbol: BHU25_25110
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: GCA_000425805_02738
symbol: dnaX
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: GCA_000425805_02741
symbol: ligA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: GCA_000425805_02742
symbol: zipA
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: GCA_000425805_02743
symbol: smc
gene_biotype: protein_coding
description:
  Unannotated protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: GCA_000425805_02748
symbol: BHU25_25045
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: GCA_000425805_02749
symbol: aqpZ
gene_biotype: protein_coding
description:
  Unannotated protein; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: GCA_000425805_02756
symbol: allA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.


ensembl_gene_id: GCA_000425805_02797
symbol: ccmE
gene_biotype: protein_coding
description:
  Unannotated protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: GCA_000425805_02798
symbol: BHU25_24785
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: GCA_000425805_02799
symbol: ccmC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: GCA_000425805_02800
symbol: BHU25_24775
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: GCA_000425805_02801
symbol: ccmA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: GCA_000425805_02812
symbol: BHU25_24715
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: GCA_000425805_02814
symbol: fliA
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: GCA_000425805_02817
symbol: flhA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: GCA_000425805_02818
symbol: flhB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: GCA_000425805_02821
symbol: fliP
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: GCA_000425805_02823
symbol: BHU25_24660
gene_biotype: protein_coding
description:
  Unannotated protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: GCA_000425805_02824
symbol: BHU25_24655
gene_biotype: protein_coding
description:
  Unannotated protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: GCA_000425805_02833
symbol: BHU25_24610
gene_biotype: protein_coding
description:
  Unannotated protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: GCA_000425805_02834
symbol: BHU25_24605
gene_biotype: protein_coding
description:
  Unannotated protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: GCA_000425805_02848
symbol: flgI
gene_biotype: protein_coding
description:
  Unannotated protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: GCA_000425805_02856
symbol: flgB
gene_biotype: protein_coding
description:
  Unannotated protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: GCA_000425805_02857
symbol: BHU25_24475
gene_biotype: protein_coding
description:
  Unannotated protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: GCA_000425805_02859
symbol: BHU25_24465
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: GCA_000425805_02900
symbol: BHU25_03980
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: GCA_000425805_02901
symbol: tatC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: GCA_000425805_02902
symbol: tatB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: GCA_000425805_02903
symbol: tatA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: GCA_000425805_02906
symbol: ubiB
gene_biotype: protein_coding
description:
  Unannotated protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: GCA_000425805_02908
symbol: ubiE
gene_biotype: protein_coding
description:
  Unannotated protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: GCA_000425805_02917
symbol: hslU
gene_biotype: protein_coding
description:
  Unannotated protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: GCA_000425805_02918
symbol: hslV
gene_biotype: protein_coding
description:
  Unannotated protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: GCA_000425805_02920
symbol: pyrB
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: GCA_000425805_02922
symbol: BHU25_04090
gene_biotype: protein_coding
description:
  Unannotated protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: GCA_000425805_02934
symbol: bioA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: GCA_000425805_02938
symbol: rhlE
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: GCA_000425805_02942
symbol: ahcY
gene_biotype: protein_coding
description:
  Unannotated protein; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: GCA_000425805_02947
symbol: BHU25_04230
gene_biotype: protein_coding
description:
  Unannotated protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: GCA_000425805_02951
symbol: metK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: GCA_000425805_02953
symbol: BHU25_04260
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: GCA_000425805_02954
symbol: BHU25_04265
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: GCA_000425805_02958
symbol: BHU25_04285
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: GCA_000425805_02971
symbol: putA
gene_biotype: protein_coding
description:
  Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: GCA_000425805_02972
symbol: BHU25_04360
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: GCA_000425805_02983
symbol: msbA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: GCA_000425805_02984
symbol: hldE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: GCA_000425805_02990
symbol: BHU25_04450
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: GCA_000425805_02992
symbol: thiC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: GCA_000425805_02997
symbol: cpdA
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: GCA_000425805_02999
symbol: parE
gene_biotype: protein_coding
description:
  Unannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: GCA_000425805_03002
symbol: parC
gene_biotype: protein_coding
description:
  Unannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: GCA_000425805_03006
symbol: psd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: GCA_000425805_03012
symbol: rsgA
gene_biotype: protein_coding
description:
  Unannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: GCA_000425805_03013
symbol: orn
gene_biotype: protein_coding
description:
  Unannotated protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: GCA_000425805_03015
symbol: queG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: GCA_000425805_03016
symbol: nnrD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.


ensembl_gene_id: GCA_000425805_03019
symbol: mutL
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: GCA_000425805_03020
symbol: miaA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: GCA_000425805_03021
symbol: hfq
gene_biotype: protein_coding
description:
  Unannotated protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: GCA_000425805_03022
symbol: hflX
gene_biotype: protein_coding
description:
  Unannotated protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: GCA_000425805_03026
symbol: purA
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: GCA_000425805_03032
symbol: rnr
gene_biotype: protein_coding
description:
  Unannotated protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: GCA_000425805_03035
symbol: rpsR
gene_biotype: protein_coding
description:
  Unannotated protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: GCA_000425805_03038
symbol: BHU25_04685
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: GCA_000425805_03049
symbol: nadE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: GCA_000425805_03050
symbol: pncB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: GCA_000425805_03068
symbol: cbpA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.


ensembl_gene_id: GCA_000425805_03069
symbol: cbpM
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ.


ensembl_gene_id: GCA_000425805_03090
symbol: cbiD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: GCA_000425805_03102
symbol: BHU25_05000
gene_biotype: protein_coding
description:
  Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: GCA_000425805_03103
symbol: dusB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: GCA_000425805_03105
symbol: prmA
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: GCA_000425805_03106
symbol: BHU25_05020
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: GCA_000425805_03139
symbol: cmoM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: GCA_000425805_03153
symbol: BHU25_05250
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: GCA_000425805_03157
symbol: BHU25_05265
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: GCA_000425805_03167
symbol: BHU25_19335
gene_biotype: protein_coding
description:
  Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: GCA_000425805_03168
symbol: BHU25_19340
gene_biotype: protein_coding
description:
  Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: GCA_000425805_03176
symbol: dctA
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: GCA_000425805_03179
symbol: ttcA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: GCA_000425805_03193
symbol: rlmD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: GCA_000425805_03199
symbol: purN
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: GCA_000425805_03208
symbol: BHU25_19545
gene_biotype: protein_coding
description:
  Unannotated protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: GCA_000425805_03209
symbol: cobB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: GCA_000425805_03211
symbol: cobD
gene_biotype: protein_coding
description:
  Unannotated protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: GCA_000425805_03213
symbol: cobQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: GCA_000425805_03214
symbol: BHU25_19575
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: GCA_000425805_03215
symbol: cobT
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: GCA_000425805_03217
symbol: cobS
gene_biotype: protein_coding
description:
  Unannotated protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: GCA_000425805_03239
symbol: BHU25_19710
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: GCA_000425805_03260
symbol: BHU25_19810
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: GCA_000425805_03261
symbol: minE
gene_biotype: protein_coding
description:
  Unannotated protein; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: GCA_000425805_03263
symbol: minC
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: GCA_000425805_03264
symbol: lpxL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: GCA_000425805_03281
symbol: mnmC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: GCA_000425805_03294
symbol: ubiG
gene_biotype: protein_coding
description:
  Unannotated protein; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: GCA_000425805_03296
symbol: mtnA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: GCA_000425805_03298
symbol: serC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: GCA_000425805_03300
symbol: aroA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: GCA_000425805_03302
symbol: BHU25_20020
gene_biotype: protein_coding
description:
  Unannotated protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: GCA_000425805_03320
symbol: pyrF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: GCA_000425805_03332
symbol: prmB
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: GCA_000425805_03335
symbol: aroC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: GCA_000425805_03343
symbol: BHU25_20315
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: GCA_000425805_03366
symbol: efp
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: GCA_000425805_03377
symbol: deaD
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: GCA_000425805_03402
symbol: lpxK
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: GCA_000425805_03404
symbol: kdsB
gene_biotype: protein_coding
description:
  Unannotated protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: GCA_000425805_03407
symbol: rne
gene_biotype: protein_coding
description:
  Unannotated protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: GCA_000425805_03411
symbol: BHU25_20680
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: GCA_000425805_03414
symbol: plsX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: GCA_000425805_03416
symbol: fabG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: GCA_000425805_03418
symbol: BHU25_20715
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: GCA_000425805_03420
symbol: mltG
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: GCA_000425805_03432
symbol: uvrB
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the [...]


ensembl_gene_id: GCA_000425805_03435
symbol: gltX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: GCA_000425805_03478
symbol: BHU25_03035
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: GCA_000425805_03480
symbol: cysA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_000425805_03503
symbol: rpiA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: GCA_000425805_03504
symbol: ilvA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: GCA_000425805_03507
symbol: rppH
gene_biotype: protein_coding
description:
  Unannotated protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: GCA_000425805_03511
symbol: lgt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: GCA_000425805_03512
symbol: thyA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: GCA_000425805_03523
symbol: BHU25_03280
gene_biotype: protein_coding
description:
  Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: GCA_000425805_03531
symbol: mutM
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: GCA_000425805_03534
symbol: coaD
gene_biotype: protein_coding
description:
  Unannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: GCA_000425805_03541
symbol: BHU25_03390
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: GCA_000425805_03544
symbol: ftsY
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: GCA_000425805_03546
symbol: BHU25_03415
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: GCA_000425805_03547
symbol: rpoH
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: GCA_000425805_03549
symbol: mtgA
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: GCA_000425805_03552
symbol: thiG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: GCA_000425805_03555
symbol: BHU25_03460
gene_biotype: protein_coding
description:
  Unannotated protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: GCA_000425805_03556
symbol: BHU25_03465
gene_biotype: protein_coding
description:
  Unannotated protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: GCA_000425805_03559
symbol: metXS
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: GCA_000425805_03562
symbol: BHU25_03495
gene_biotype: protein_coding
description:
  Unannotated protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: GCA_000425805_03568
symbol: priA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: GCA_000425805_03578
symbol: aroK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: GCA_000425805_03579
symbol: aroB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: GCA_000425805_03583
symbol: hemE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: GCA_000425805_03593
symbol: BHU25_03665
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: GCA_000425805_03606
symbol: selO
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: GCA_000425805_03608
symbol: nhaP2
gene_biotype: protein_coding
description:
  Unannotated protein; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.


ensembl_gene_id: GCA_000425805_03610
symbol: betA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: GCA_000425805_03611
symbol: betB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: GCA_000425805_03620
symbol: BHU25_03805
gene_biotype: protein_coding
description:
  Unannotated protein; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: GCA_000425805_03621
symbol: secB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: GCA_000425805_03622
symbol: trmL
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: GCA_000425805_03624
symbol: ntrC
gene_biotype: protein_coding
description:
  Unannotated protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: GCA_000425805_03627
symbol: thiI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: GCA_000425805_03630
symbol: BHU25_03870
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: GCA_000425805_03635
symbol: BHU25_03895
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: GCA_000425805_03644
symbol: dusC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: GCA_000425805_03648
symbol: leuC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: GCA_000425805_03649
symbol: leuD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: GCA_000425805_03651
symbol: leuB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: GCA_000425805_03652
symbol: asd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: GCA_000425805_03655
symbol: truA
gene_biotype: protein_coding
description:
  Unannotated protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: GCA_000425805_03657
symbol: accD
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: GCA_000425805_03661
symbol: purF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: GCA_000425805_03662
symbol: metZ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: GCA_000425805_03677
symbol: BHU25_21110
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.


ensembl_gene_id: GCA_000425805_03679
symbol: nadK
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: GCA_000425805_03693
symbol: sbcD
gene_biotype: protein_coding
description:
  Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: GCA_000425805_03705
symbol: BHU25_21270
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: GCA_000425805_03706
symbol: BHU25_21275
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: GCA_000425805_03708
symbol: BHU25_21285
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: GCA_000425805_03719
symbol: pyrD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: GCA_000425805_03721
symbol: rlmL
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: GCA_000425805_03740
symbol: rlmM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: GCA_000425805_03741
symbol: tusA
gene_biotype: protein_coding
description:
  Unannotated protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: GCA_000425805_03743
symbol: pdxB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: GCA_000425805_03752
symbol: BHU25_08365
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: GCA_000425805_03755
symbol: BHU25_08380
gene_biotype: protein_coding
description:
  Unannotated protein; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.


ensembl_gene_id: GCA_000425805_03765
symbol: fadB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: GCA_000425805_03766
symbol: fadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: GCA_000425805_03768
symbol: topA
gene_biotype: protein_coding
description:
  Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: GCA_000425805_03771
symbol: BHU25_08460
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: GCA_000425805_03772
symbol: lexA
gene_biotype: protein_coding
description:
  Unannotated protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: GCA_000425805_03775
symbol: nagZ
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: GCA_000425805_03778
symbol: mfd
gene_biotype: protein_coding
description:
  Unannotated protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: GCA_000425805_03780
symbol: BHU25_08505
gene_biotype: protein_coding
description:
  Unannotated protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: GCA_000425805_03781
symbol: sthA
gene_biotype: protein_coding
description:
  Unannotated protein; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: GCA_000425805_03785
symbol: lolD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: GCA_000425805_03790
symbol: queF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: GCA_000425805_03798
symbol: tal
gene_biotype: protein_coding
description:
  Unannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: GCA_000425805_03799
symbol: dusA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: GCA_000425805_03913
symbol: dnaE2
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: GCA_000425805_03952
symbol: uvrC
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: GCA_000425805_03958
symbol: BHU25_12915
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: GCA_000425805_03986
symbol: clsB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: GCA_000425805_04019
symbol: BHU25_15725
gene_biotype: protein_coding
description:
  Unannotated protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: GCA_000425805_04029
symbol: recC
gene_biotype: protein_coding
description:
  Unannotated protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme  [...]


ensembl_gene_id: GCA_000425805_04059
symbol: trmA
gene_biotype: protein_coding
description:
  Unannotated protein; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: GCA_000425805_04068
symbol: mscL
gene_biotype: protein_coding
description:
  Unannotated protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: GCA_000425805_04069
symbol: radA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: GCA_000425805_04071
symbol: BHU25_01375
gene_biotype: protein_coding
description:
  Unannotated protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: GCA_000425805_04090
symbol: rplU
gene_biotype: protein_coding
description:
  Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: GCA_000425805_04092
symbol: obgE
gene_biotype: protein_coding
description:
  Unannotated protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: GCA_000425805_04093
symbol: proB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: GCA_000425805_04136
symbol: ychF
gene_biotype: protein_coding
description:
  Unannotated protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: GCA_000425805_04137
symbol: pth
gene_biotype: protein_coding
description:
  Unannotated protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: GCA_000425805_04138
symbol: rplY
gene_biotype: protein_coding
description:
  Unannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: GCA_000425805_04139
symbol: prs
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: GCA_000425805_04142
symbol: lolB
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: GCA_000425805_04144
symbol: hemA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: GCA_000425805_04145
symbol: prfA
gene_biotype: protein_coding
description:
  Unannotated protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: GCA_000425805_04146
symbol: prmC
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: GCA_000425805_04149
symbol: BHU25_01100
gene_biotype: protein_coding
description:
  Unannotated protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.


ensembl_gene_id: GCA_000425805_04152
symbol: BHU25_01075
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers; Belongs to the bacterial renalase family.


ensembl_gene_id: GCA_000425805_04154
symbol: hemH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: GCA_000425805_04156
symbol: upp
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: GCA_000425805_04173
symbol: rsmC
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: GCA_000425805_04205
symbol: BHU25_00900
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: GCA_000425805_04281
symbol: nuoN
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: GCA_000425805_04284
symbol: nuoK
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: GCA_000425805_04285
symbol: BHU25_21860
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: GCA_000425805_04287
symbol: nuoH
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: GCA_000425805_04288
symbol: BHU25_21875
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: GCA_000425805_04289
symbol: BHU25_21880
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: GCA_000425805_04291
symbol: nuoC
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: GCA_000425805_04292
symbol: nuoB
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: GCA_000425805_04293
symbol: nuoA
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: GCA_000425805_04301
symbol: mnmA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: GCA_000425805_04306
symbol: clpS
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: GCA_000425805_04308
symbol: infA
gene_biotype: protein_coding
description:
  Unannotated protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: GCA_000425805_04309
symbol: bpt
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: GCA_000425805_04310
symbol: aat
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: GCA_000425805_04314
symbol: crcB
gene_biotype: protein_coding
description:
  Unannotated protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: GCA_000425805_04315
symbol: serS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: GCA_000425805_04316
symbol: cysG
gene_biotype: protein_coding
description:
  Unannotated protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: GCA_000425805_04395
symbol: argC-2
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: GCA_000425805_04401
symbol: BHU25_22950
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: GCA_000425805_04590
symbol: fieF
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: GCA_000425805_04595
symbol: amn
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: GCA_000425805_04599
symbol: thiE
gene_biotype: protein_coding
description:
  Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: GCA_000425805_04603
symbol: miaB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: GCA_000425805_04605
symbol: ybeY
gene_biotype: protein_coding
description:
  Unannotated protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: GCA_000425805_04607
symbol: lnt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: GCA_000425805_04610
symbol: lptE
gene_biotype: protein_coding
description:
  Unannotated protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: GCA_000425805_04615
symbol: lipA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: GCA_000425805_04616
symbol: lipB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: GCA_000425805_04621
symbol: mrdB
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: GCA_000425805_04622
symbol: mrdA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: GCA_000425805_04623
symbol: rlmH
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: GCA_000425805_04624
symbol: rsfS
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: GCA_000425805_04625
symbol: nadD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: GCA_000425805_04626
symbol: proA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: GCA_000425805_04636
symbol: ubiX
gene_biotype: protein_coding
description:
  Unannotated protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: GCA_000425805_04637
symbol: mpl
gene_biotype: protein_coding
description:
  Unannotated protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: GCA_000425805_04646
symbol: ppa
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: GCA_000425805_04652
symbol: xseB
gene_biotype: protein_coding
description:
  Unannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: GCA_000425805_04654
symbol: dxs
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: GCA_000425805_04658
symbol: ribA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: GCA_000425805_04660
symbol: BHU25_05635
gene_biotype: protein_coding
description:
  Unannotated protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: GCA_000425805_04661
symbol: thiL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: GCA_000425805_04662
symbol: nusB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: GCA_000425805_04663
symbol: ribH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: GCA_000425805_04664
symbol: ribB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: GCA_000425805_04666
symbol: BHU25_05605
gene_biotype: protein_coding
description:
  Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: GCA_000425805_04667
symbol: nrdR
gene_biotype: protein_coding
description:
  Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: GCA_000425805_04682
symbol: selA
gene_biotype: protein_coding
description:
  Unannotated protein; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: GCA_000425805_04689
symbol: BHU25_05470
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: GCA_000425805_04691
symbol: uvrA
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: GCA_000425805_04695
symbol: rpoA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: GCA_000425805_04696
symbol: rpsD
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: GCA_000425805_04697
symbol: rpsK
gene_biotype: protein_coding
description:
  Unannotated protein; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: GCA_000425805_04698
symbol: rpsM
gene_biotype: protein_coding
description:
  Unannotated protein; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: GCA_000425805_04699
symbol: secY
gene_biotype: protein_coding
description:
  Unannotated protein; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: GCA_000425805_04702
symbol: rpsE
gene_biotype: protein_coding
description:
  Unannotated protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: GCA_000425805_04703
symbol: rplR
gene_biotype: protein_coding
description:
  Unannotated protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: GCA_000425805_04704
symbol: rplF
gene_biotype: protein_coding
description:
  Unannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: GCA_000425805_04705
symbol: rpsH
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: GCA_000425805_04706
symbol: rpsN
gene_biotype: protein_coding
description:
  Unannotated protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: GCA_000425805_04707
symbol: rplE
gene_biotype: protein_coding
description:
  Unannotated protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: GCA_000425805_04708
symbol: rplX
gene_biotype: protein_coding
description:
  Unannotated protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: GCA_000425805_04709
symbol: rplN
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: GCA_000425805_04710
symbol: rpsQ
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: GCA_000425805_04712
symbol: rplP
gene_biotype: protein_coding
description:
  Unannotated protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: GCA_000425805_04713
symbol: rpsC
gene_biotype: protein_coding
description:
  Unannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: GCA_000425805_04714
symbol: rplV
gene_biotype: protein_coding
description:
  Unannotated protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: GCA_000425805_04715
symbol: rpsS
gene_biotype: protein_coding
description:
  Unannotated protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: GCA_000425805_04716
symbol: rplB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: GCA_000425805_04717
symbol: rplW
gene_biotype: protein_coding
description:
  Unannotated protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: GCA_000425805_04719
symbol: rplC
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: GCA_000425805_04720
symbol: rpsJ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: GCA_000425805_04722
symbol: msrQ
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the  [...]


ensembl_gene_id: GCA_000425805_04723
symbol: msrP
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) [...]


ensembl_gene_id: GCA_000425805_04725
symbol: ilvC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: GCA_000425805_04730
symbol: BHU25_06480
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: GCA_000425805_04734
symbol: hmuV
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_000425805_04740
symbol: dksA
gene_biotype: protein_coding
description:
  Unannotated protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: GCA_000425805_04741
symbol: gluQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: GCA_000425805_04745
symbol: pcnB
gene_biotype: protein_coding
description:
  Unannotated protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: GCA_000425805_04748
symbol: panC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: GCA_000425805_04751
symbol: acsA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: GCA_000425805_04757
symbol: pnp
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: GCA_000425805_04758
symbol: rpsO
gene_biotype: protein_coding
description:
  Unannotated protein; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: GCA_000425805_04759
symbol: truB
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: GCA_000425805_04760
symbol: rbfA
gene_biotype: protein_coding
description:
  Unannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: GCA_000425805_04761
symbol: infB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: GCA_000425805_04766
symbol: BHU25_06305
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: GCA_000425805_04767
symbol: tpiA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: GCA_000425805_04768
symbol: glmM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: GCA_000425805_04769
symbol: BHU25_06290
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: GCA_000425805_04770
symbol: hflB
gene_biotype: protein_coding
description:
  Unannotated protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: GCA_000425805_04771
symbol: rlmE
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: GCA_000425805_04774
symbol: greA
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: GCA_000425805_04777
symbol: dapB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: GCA_000425805_04778
symbol: dnaJ
gene_biotype: protein_coding
description:
  Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]


ensembl_gene_id: GCA_000425805_04780
symbol: grpE
gene_biotype: protein_coding
description:
  Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]


ensembl_gene_id: GCA_000425805_04787
symbol: smpB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to  [...]


ensembl_gene_id: GCA_000425805_04789
symbol: BHU25_06195
gene_biotype: protein_coding
description:
  Unannotated protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: GCA_000425805_04790
symbol: lldD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.


ensembl_gene_id: GCA_000425805_04835
symbol: murJ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: GCA_000425805_04837
symbol: ileS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: GCA_000425805_04838
symbol: lspA
gene_biotype: protein_coding
description:
  Unannotated protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: GCA_000425805_04840
symbol: ispH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: GCA_000425805_04859
symbol: clpB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: GCA_000425805_04869
symbol: yacG
gene_biotype: protein_coding
description:
  Unannotated protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: GCA_000425805_04870
symbol: coaE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: GCA_000425805_04871
symbol: BHU25_15530
gene_biotype: protein_coding
description:
  Unannotated protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: GCA_000425805_04946
symbol: alaS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: GCA_000425805_04948
symbol: astE
gene_biotype: protein_coding
description:
  Unannotated protein; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: GCA_000425805_04950
symbol: astB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: GCA_000425805_04951
symbol: astD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: GCA_000425805_04954
symbol: argD
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: GCA_000425805_04979
symbol: BHU25_24135
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: GCA_000425805_04980
symbol: BHU25_24130
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: GCA_000425805_04983
symbol: BHU25_24115
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: GCA_000425805_04990
symbol: BHU25_24080
gene_biotype: protein_coding
description:
  Unannotated protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: GCA_000425805_05122
symbol: BHU25_13595
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.


ensembl_gene_id: GCA_000425805_05218
symbol: secE
gene_biotype: protein_coding
description:
  Unannotated protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: GCA_000425805_05220
symbol: rplK
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: GCA_000425805_05221
symbol: rplA
gene_biotype: protein_coding
description:
  Unannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: GCA_000425805_05222
symbol: rplJ
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: GCA_000425805_05223
symbol: rplL
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: GCA_000425805_05226
symbol: rpsL
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: GCA_000425805_05227
symbol: rpsG
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: GCA_000425805_05278
symbol: coaX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: GCA_000425805_05279
symbol: birA
gene_biotype: protein_coding
description:
  Unannotated protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


