# geneInfo

ensembl_gene_id: H681_00005
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: H681_00010
symbol: AGI21884.1
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: H681_00015
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: H681_00020
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: H681_00030
symbol: AGI21888.1
gene_biotype: protein_coding
description:
  Restriction endonuclease, type I, EcoRI, R subunit/type III; COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.


ensembl_gene_id: H681_00060
symbol: AGI21894.1
gene_biotype: protein_coding
description:
  Heat shock protein dnaj domain-containing protein; COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain.


ensembl_gene_id: H681_00095
symbol: AGI21901.1
gene_biotype: protein_coding
description:
  Transposition helper protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.


ensembl_gene_id: H681_00120
symbol: AGI21906.1
gene_biotype: protein_coding
description:
  Hipa-like c-terminal domain protein; COG3550 Uncharacterized protein related to capsule biosynthesis enzymes.


ensembl_gene_id: H681_00210
symbol: mntH
gene_biotype: protein_coding
description:
  Manganese transport protein MntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: H681_00220
symbol: AGI21926.1
gene_biotype: protein_coding
description:
  Ectoine/hydroxyectoine ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: H681_00225
symbol: AGI21927.1
gene_biotype: protein_coding
description:
  Ectoine/hydroxyectoine ABC transporter permease EhuD; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: H681_00230
symbol: AGI21928.1
gene_biotype: protein_coding
description:
  Ectoine/hydroxyectoine ABC transporter permease EhuC; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: H681_00235
symbol: AGI21929.1
gene_biotype: protein_coding
description:
  Ectoine/hydroxyectoine ABC transporter solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_00240
symbol: AGI21930.1
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: H681_00250
symbol: AGI21932.1
gene_biotype: protein_coding
description:
  Ectoine utilization protein EutC; COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog.


ensembl_gene_id: H681_00270
symbol: AGI21936.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: H681_00280
symbol: AGI21938.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H681_00290
symbol: trkA
gene_biotype: protein_coding
description:
  Potassium transporter peripheral membrane component; COG0569 K+ transport systems, NAD-binding component.


ensembl_gene_id: H681_00295
symbol: AGI21941.1
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: H681_00300
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: H681_00305
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: H681_00315
symbol: AGI21945.1
gene_biotype: protein_coding
description:
  DNA protecting protein DprA; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: H681_00320
symbol: tsaC
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: H681_00330
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: H681_00335
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: H681_00365
symbol: AGI21955.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_00400
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: H681_00405
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: H681_00470
symbol: AGI21976.1
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: H681_00510
symbol: AGI21984.1
gene_biotype: protein_coding
description:
  3-guanidinopropionase GpuA; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: H681_00580
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: H681_00585
symbol: AGI21999.1
gene_biotype: protein_coding
description:
  Phosphomannose isomerase/GDP-mannose WbpW; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: H681_00590
symbol: AGI22000.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: H681_00595
symbol: AGI22001.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component.


ensembl_gene_id: H681_00625
symbol: AGI22007.1
gene_biotype: protein_coding
description:
  NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: H681_00640
symbol: AGI22010.1
gene_biotype: protein_coding
description:
  COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: H681_00645
symbol: cyoE
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: H681_00680
symbol: AGI22018.1
gene_biotype: protein_coding
description:
  Cytochrome-c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: H681_00685
symbol: AGI22019.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: H681_00695
symbol: AGI22021.1
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: H681_00745
symbol: AGI22031.1
gene_biotype: protein_coding
description:
  Beta alanine--pyruvate transaminase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H681_00750
symbol: AGI22032.1
gene_biotype: protein_coding
description:
  Cupin 2 protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: H681_00760
symbol: AGI22034.1
gene_biotype: protein_coding
description:
  Polyamine ABC transporter periplasmic polyamine-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_00765
symbol: AGI22035.1
gene_biotype: protein_coding
description:
  Putative GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: H681_00790
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis-specific methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: H681_00795
symbol: cheD
gene_biotype: protein_coding
description:
  Chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: H681_00800
symbol: AGI22042.1
gene_biotype: protein_coding
description:
  Putative chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: H681_00835
symbol: AGI22049.1
gene_biotype: protein_coding
description:
  Putative ATP-binding component of ABC transporter; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: H681_00840
symbol: AGI22050.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: H681_00845
symbol: AGI22051.1
gene_biotype: protein_coding
description:
  Sulfate ester transport system substrate-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: H681_00870
symbol: AGI22056.1
gene_biotype: protein_coding
description:
  Hydroxydechloroatrazine ethylaminohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: H681_00875
symbol: AGI22057.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_00930
symbol: AGI22068.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: H681_00940
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: H681_00955
symbol: AGI22073.1
gene_biotype: protein_coding
description:
  ChaC-like protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: H681_00970
symbol: AGI22076.1
gene_biotype: protein_coding
description:
  Putative TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: H681_00975
symbol: AGI22077.1
gene_biotype: protein_coding
description:
  Putative TonB-dependent receptor; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.


ensembl_gene_id: H681_00985
symbol: metN
gene_biotype: protein_coding
description:
  DL-methionine transporter ATP-binding subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_00995
symbol: AGI22081.1
gene_biotype: protein_coding
description:
  ABC zinc transporter permease ZnuB; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.


ensembl_gene_id: H681_01000
symbol: znuC
gene_biotype: protein_coding
description:
  Zinc transporter; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: H681_01005
symbol: AGI22083.1
gene_biotype: protein_coding
description:
  Transcriptional regulator np20; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: H681_01015
symbol: AGI22085.1
gene_biotype: protein_coding
description:
  NrdJa; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: H681_01025
symbol: thrB
gene_biotype: protein_coding
description:
  COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: H681_01035
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: H681_01040
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: H681_01075
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: H681_01090
symbol: AGI22100.1
gene_biotype: protein_coding
description:
  Glycosyltransferase family protein; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: H681_01135
symbol: dksA
gene_biotype: protein_coding
description:
  RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: H681_01155
symbol: AGI22113.1
gene_biotype: protein_coding
description:
  TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: H681_01170
symbol: AGI22116.1
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: H681_01200
symbol: AGI22122.1
gene_biotype: protein_coding
description:
  Protein DitG; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_01235
symbol: gabD
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase I; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: H681_01240
symbol: AGI22130.1
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H681_01250
symbol: AGI22132.1
gene_biotype: protein_coding
description:
  Alginate biosynthesis protein AlgZ/FimS; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.


ensembl_gene_id: H681_01260
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: H681_01265
symbol: AGI22135.1
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: H681_01280
symbol: AGI22138.1
gene_biotype: protein_coding
description:
  Putative soluble quinoprotein glucose/sorbosone dehydrogenase; COG2133 Glucose/sorbosone dehydrogenases.


ensembl_gene_id: H681_01285
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: H681_01310
symbol: AGI22144.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: H681_01320
symbol: AGI22146.1
gene_biotype: protein_coding
description:
  Putative integral membrane transport protein; COG0861 Membrane protein TerC, possibly involved in tellurium resistance.


ensembl_gene_id: H681_01345
symbol: AGI22151.1
gene_biotype: protein_coding
description:
  Isoprenoid biosynthesis protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: H681_01365
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: H681_01380
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: H681_01385
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: H681_01400
symbol: AGI22162.1
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL-like protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: H681_01410
symbol: AGI22164.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein/permease; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: H681_01435
symbol: AGI22169.1
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: H681_01440
symbol: AGI22170.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: H681_01470
symbol: AGI22176.1
gene_biotype: protein_coding
description:
  Binding protein component of ABC iron transporter; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: H681_01475
symbol: AGI22177.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: H681_01480
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: H681_01485
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: H681_01490
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: H681_01535
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: H681_01565
symbol: AGI22195.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: H681_01570
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: H681_01590
symbol: nudE
gene_biotype: protein_coding
description:
  Adenosine nucleotide hydrolase NudE; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: H681_01595
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: H681_01600
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: H681_01630
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: H681_01670
symbol: AGI22216.1
gene_biotype: protein_coding
description:
  Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: H681_01685
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: H681_01690
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: H681_01695
symbol: AGI22221.1
gene_biotype: protein_coding
description:
  Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: H681_01700
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: H681_01710
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: H681_01725
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: H681_01730
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: H681_01750
symbol: AGI22232.1
gene_biotype: protein_coding
description:
  HemN family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: H681_01755
symbol: AGI22233.1
gene_biotype: protein_coding
description:
  dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: H681_01770
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: H681_01790
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: H681_01795
symbol: AGI22241.1
gene_biotype: protein_coding
description:
  Alanine racemase domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: H681_01830
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: H681_01835
symbol: pyrR
gene_biotype: protein_coding
description:
  Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: H681_01840
symbol: AGI22250.1
gene_biotype: protein_coding
description:
  Holliday junction resolvase-like protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: H681_01845
symbol: AGI22251.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: H681_01855
symbol: gshB
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: H681_01885
symbol: AGI22259.1
gene_biotype: protein_coding
description:
  CheA signal transduction histidine kinase; COG0643 Chemotaxis protein histidine kinase and related kinases.


ensembl_gene_id: H681_01890
symbol: AGI22260.1
gene_biotype: protein_coding
description:
  CheB methylesterase; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain.


ensembl_gene_id: H681_01900
symbol: AGI22262.1
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: H681_01905
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: H681_01930
symbol: AGI22268.1
gene_biotype: protein_coding
description:
  Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein MexA precursor; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_01965
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: H681_01970
symbol: tatB
gene_biotype: protein_coding
description:
  Translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: H681_01975
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: H681_01985
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: H681_01990
symbol: ubiB
gene_biotype: protein_coding
description:
  2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: H681_02000
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: H681_02030
symbol: AGI22288.1
gene_biotype: protein_coding
description:
  Poly(3-hydroxyalkanoate) depolymerase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_02045
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: H681_02050
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: H681_02065
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: H681_02105
symbol: AGI22303.1
gene_biotype: protein_coding
description:
  Periplasmic transport system; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_02155
symbol: AGI22313.1
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H681_02185
symbol: AGI22319.1
gene_biotype: protein_coding
description:
  Streptogramin lyase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.


ensembl_gene_id: H681_02225
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: H681_02230
symbol: AGI22328.1
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: H681_02245
symbol: srkA
gene_biotype: protein_coding
description:
  Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: H681_02275
symbol: pxpA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: H681_02280
symbol: AGI22338.1
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: H681_02305
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: H681_02310
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: H681_02315
symbol: AGI22345.1
gene_biotype: protein_coding
description:
  Putative biotin biosynthesis protein bioH; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_02320
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: H681_02325
symbol: bioD
gene_biotype: protein_coding
description:
  Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: H681_02370
symbol: AGI22356.1
gene_biotype: protein_coding
description:
  Transcriptional regulator Anr; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H681_02415
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: H681_02420
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: H681_02430
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: H681_02435
symbol: plsY
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: H681_02440
symbol: AGI22370.1
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: H681_02445
symbol: AGI22371.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: H681_02450
symbol: cca
gene_biotype: protein_coding
description:
  2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: H681_02475
symbol: glpE
gene_biotype: protein_coding
description:
  Thiosulfate sulfurtransferase; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: H681_02480
symbol: apaH
gene_biotype: protein_coding
description:
  Diadenosine tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: H681_02490
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: H681_02495
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: H681_02500
symbol: surA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: H681_02505
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: H681_02525
symbol: AGI22387.1
gene_biotype: protein_coding
description:
  Nucleotidyltransferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: H681_02535
symbol: AGI22389.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_02540
symbol: AGI22390.1
gene_biotype: protein_coding
description:
  Sensory box histidine kinase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_02550
symbol: AGI22392.1
gene_biotype: protein_coding
description:
  Putative binding protein component of ABC transporter; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_02555
symbol: potA
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_02560
symbol: AGI22394.1
gene_biotype: protein_coding
description:
  Putative ABC transporter binding protein subunit; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_02570
symbol: AGI22396.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: H681_02580
symbol: AGI22398.1
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: H681_02585
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: H681_02595
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: H681_02605
symbol: AGI22403.1
gene_biotype: protein_coding
description:
  DNA-binding transcriptional dual regulator Crp; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H681_02615
symbol: speD
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.


ensembl_gene_id: H681_02620
symbol: coq7
gene_biotype: protein_coding
description:
  Putative ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: H681_02625
symbol: AGI22407.1
gene_biotype: protein_coding
description:
  HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: H681_02635
symbol: AGI22409.1
gene_biotype: protein_coding
description:
  COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_02660
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: H681_02665
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: H681_02670
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: H681_02685
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: H681_02690
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: H681_02695
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: H681_02705
symbol: tuf
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: H681_02710
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: H681_02715
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: H681_02720
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: H681_02725
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: H681_02730
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: H681_02735
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: H681_02740
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: H681_02750
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: H681_02755
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: H681_02760
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: H681_02770
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: H681_02775
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: H681_02785
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: H681_02790
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: H681_02795
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: H681_02800
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: H681_02805
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: H681_02810
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: H681_02820
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: H681_02825
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: H681_02830
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: H681_02835
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: H681_02840
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: H681_02845
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: H681_02850
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: H681_02855
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: H681_02860
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: H681_02870
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: H681_02875
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: H681_02885
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: H681_02890
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: H681_02895
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: H681_02900
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: H681_02915
symbol: AGI22465.1
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: H681_02930
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: H681_02940
symbol: AGI22470.1
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: H681_02965
symbol: AGI22475.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: H681_02980
symbol: AGI22478.1
gene_biotype: protein_coding
description:
  DNA mismatch endonuclease Vsr; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: H681_03005
symbol: AGI22483.1
gene_biotype: protein_coding
description:
  Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.


ensembl_gene_id: H681_03025
symbol: cbiD
gene_biotype: protein_coding
description:
  cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: H681_03055
symbol: AGI22493.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: H681_03060
symbol: cobN
gene_biotype: protein_coding
description:
  Cobaltochelatase subunit CobN; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: H681_03100
symbol: AGI22502.1
gene_biotype: protein_coding
description:
  COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: H681_03110
symbol: AGI22504.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: H681_03140
symbol: AGI22510.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: H681_03170
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: H681_03175
symbol: AGI22517.1
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: H681_03185
symbol: ribB
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: H681_03190
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: H681_03195
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: H681_03200
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: H681_03205
symbol: AGI22523.1
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: H681_03210
symbol: AGI22524.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_03220
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: H681_03235
symbol: AGI22529.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: H681_03270
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: H681_03275
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: H681_03280
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: H681_03285
symbol: rlmH
gene_biotype: protein_coding
description:
  rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: H681_03290
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: H681_03295
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: H681_03305
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: H681_03310
symbol: AGI22544.1
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.


ensembl_gene_id: H681_03320
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: H681_03325
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: H681_03370
symbol: lptE
gene_biotype: protein_coding
description:
  Hypothetical protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: H681_03390
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: H681_03400
symbol: ybeY
gene_biotype: protein_coding
description:
  Metal-binding heat shock protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: H681_03410
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: H681_03430
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: H681_03435
symbol: AGI22569.1
gene_biotype: protein_coding
description:
  Bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.


ensembl_gene_id: H681_03500
symbol: AGI22582.1
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_03530
symbol: AGI22588.1
gene_biotype: protein_coding
description:
  HicB protein; COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters.


ensembl_gene_id: H681_03535
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: H681_03540
symbol: AGI22590.1
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: H681_03555
symbol: AGI22593.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase E; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: H681_03575
symbol: AGI22597.1
gene_biotype: protein_coding
description:
  Cation efflux family protein; COG0053 Predicted Co/Zn/Cd cation transporters; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: H681_03610
symbol: AGI22604.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_03690
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: H681_03695
symbol: AGI22621.1
gene_biotype: protein_coding
description:
  Putative L-malate dehydrogenase; COG2055 Malate/L-lactate dehydrogenases; Belongs to the LDH2/MDH2 oxidoreductase family.


ensembl_gene_id: H681_03715
symbol: AGI22625.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: H681_03735
symbol: AGI22629.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_03755
symbol: AGI22633.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: H681_03780
symbol: AGI22638.1
gene_biotype: protein_coding
description:
  Geranyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: H681_03785
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: H681_03860
symbol: AGI22654.1
gene_biotype: protein_coding
description:
  ClpB protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: H681_03985
symbol: AGI22679.1
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: H681_03990
symbol: AGI22680.1
gene_biotype: protein_coding
description:
  5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H681_03995
symbol: AGI22681.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_04010
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: H681_04015
symbol: AGI22685.1
gene_biotype: protein_coding
description:
  Zinc-dependent peptidase; COG3228 Uncharacterized protein conserved in bacteria; Belongs to the MtfA family.


ensembl_gene_id: H681_04060
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: H681_04065
symbol: ubiX
gene_biotype: protein_coding
description:
  Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: H681_04120
symbol: prpB
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: H681_04145
symbol: AGI22711.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: H681_04155
symbol: AGI22713.1
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: H681_04160
symbol: AGI22714.1
gene_biotype: protein_coding
description:
  Two-component sensor; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.


ensembl_gene_id: H681_04195
symbol: AGI22721.1
gene_biotype: protein_coding
description:
  DNA-O6-methylguanine--protein-cysteine S-methyltransferase/transcriptional regulator Ada; COG2169 Adenosine deaminase.


ensembl_gene_id: H681_04200
symbol: AGI22722.1
gene_biotype: protein_coding
description:
  Multi-sensor hybrid histidine kinase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_04205
symbol: AGI22723.1
gene_biotype: protein_coding
description:
  Cyclic di-GMP phosphodiesterase; COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain.


ensembl_gene_id: H681_04225
symbol: AGI22727.1
gene_biotype: protein_coding
description:
  HicB family protein; COG4226 Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters.


ensembl_gene_id: H681_04255
symbol: AGI22733.1
gene_biotype: protein_coding
description:
  RND family efflux transporter MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_04290
symbol: AGI22740.1
gene_biotype: protein_coding
description:
  Crp/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H681_04335
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: H681_04350
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: H681_04405
symbol: AGI22761.1
gene_biotype: protein_coding
description:
  Conjugative transposon DNA recombination protein; COG3593 Predicted ATP-dependent endonuclease of the OLD family.


ensembl_gene_id: H681_04420
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.


ensembl_gene_id: H681_04435
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: H681_04440
symbol: AGI22768.1
gene_biotype: protein_coding
description:
  Choline/carnitine/betaine transporter family protein; COG1292 Choline-glycine betaine transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: H681_04465
symbol: AGI22773.1
gene_biotype: protein_coding
description:
  Transposase InsF for insertion sequence IS3A/B/C/D/E/fA; COG2801 Transposase and inactivated derivatives.


ensembl_gene_id: H681_04570
symbol: AGI22794.1
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: H681_04640
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: H681_04650
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: H681_04655
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: H681_04670
symbol: murJ
gene_biotype: protein_coding
description:
  Protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: H681_04675
symbol: AGI22815.1
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family.


ensembl_gene_id: H681_04680
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: H681_04685
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: H681_04695
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: H681_04755
symbol: bamD
gene_biotype: protein_coding
description:
  Competence protein ComL; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: H681_04760
symbol: AGI22832.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: H681_04765
symbol: AGI22833.1
gene_biotype: protein_coding
description:
  Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: H681_04770
symbol: clpB
gene_biotype: protein_coding
description:
  clpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: H681_04795
symbol: AGI22839.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: H681_04810
symbol: AGI22842.1
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: H681_04830
symbol: AGI22846.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_04835
symbol: AGI22847.1
gene_biotype: protein_coding
description:
  Non-heme chloroperoxidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_04850
symbol: AGI22850.1
gene_biotype: protein_coding
description:
  COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: H681_04915
symbol: yacG
gene_biotype: protein_coding
description:
  DNA gyrase inhibitor; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: H681_04920
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: H681_04925
symbol: AGI22865.1
gene_biotype: protein_coding
description:
  Type 4 prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: H681_04935
symbol: AGI22867.1
gene_biotype: protein_coding
description:
  Type 4 fimbrial biogenesis protein PilB; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: H681_04975
symbol: AGI22875.1
gene_biotype: protein_coding
description:
  N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression.


ensembl_gene_id: H681_05000
symbol: AGI22880.1
gene_biotype: protein_coding
description:
  Multiphosphoryl transfer protein; COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: H681_05005
symbol: AGI22881.1
gene_biotype: protein_coding
description:
  1-phosphofructokinase; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: H681_05010
symbol: AGI22882.1
gene_biotype: protein_coding
description:
  PTS system fructose-specific transporter subunits IIBC; COG1445 Phosphotransferase system fructose-specific component IIB.


ensembl_gene_id: H681_05020
symbol: arnF
gene_biotype: protein_coding
description:
  4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: H681_05025
symbol: arnE
gene_biotype: protein_coding
description:
  Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.


ensembl_gene_id: H681_05030
symbol: arnT
gene_biotype: protein_coding
description:
  4-amino-4-deoxy-L-arabinose transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.


ensembl_gene_id: H681_05035
symbol: arnD
gene_biotype: protein_coding
description:
  4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase ArnD; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: H681_05040
symbol: arnA
gene_biotype: protein_coding
description:
  Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily.


ensembl_gene_id: H681_05045
symbol: arnC
gene_biotype: protein_coding
description:
  Putative glycosyl transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: H681_05050
symbol: arnB
gene_biotype: protein_coding
description:
  UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: H681_05065
symbol: AGI22893.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter permease; COG4215 ABC-type arginine transport system, permease component.


ensembl_gene_id: H681_05070
symbol: AGI22894.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter permease; COG4160 ABC-type arginine/histidine transport system, permease component.


ensembl_gene_id: H681_05090
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: H681_05125
symbol: AGI22905.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthetic protein LpxO1; COG3555 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases.


ensembl_gene_id: H681_05160
symbol: dppF
gene_biotype: protein_coding
description:
  Dipeptide transporter ATP-binding subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_05165
symbol: AGI22913.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_05170
symbol: AGI22914.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H681_05175
symbol: AGI22915.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: H681_05180
symbol: AGI22916.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: H681_05205
symbol: AGI22921.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: H681_05225
symbol: AGI22925.1
gene_biotype: protein_coding
description:
  Two component Fis family transcriptional regulator; COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain.


ensembl_gene_id: H681_05230
symbol: AGI22926.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4178 ABC-type uncharacterized transport system, permease and ATPase components.


ensembl_gene_id: H681_05285
symbol: AGI22937.1
gene_biotype: protein_coding
description:
  4-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


ensembl_gene_id: H681_05295
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: H681_05300
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: H681_05305
symbol: gatC
gene_biotype: protein_coding
description:
  asparaginyl/glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: H681_05320
symbol: AGI22944.1
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: H681_05325
symbol: AGI22945.1
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: H681_05355
symbol: AGI22951.1
gene_biotype: protein_coding
description:
  Putative modulator of DNA gyrase; COG0312 Predicted Zn-dependent proteases and their inactivated homologs.


ensembl_gene_id: H681_05370
symbol: AGI22954.1
gene_biotype: protein_coding
description:
  Nitrogen regulatory IIA protein; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: H681_05380
symbol: AGI22956.1
gene_biotype: protein_coding
description:
  RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: H681_05385
symbol: AGI22957.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1137 ABC-type (unclassified) transport system, ATPase component.


ensembl_gene_id: H681_05390
symbol: lptA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: H681_05395
symbol: lptC
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.


ensembl_gene_id: H681_05400
symbol: AGI22960.1
gene_biotype: protein_coding
description:
  YrbI family phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: H681_05410
symbol: AGI22962.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.


ensembl_gene_id: H681_05415
symbol: AGI22963.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG0767 ABC-type transport system involved in resistance to organic solvents, permease component.


ensembl_gene_id: H681_05420
symbol: AGI22964.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: H681_05425
symbol: AGI22965.1
gene_biotype: protein_coding
description:
  Toluene tolerance protein; COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component.


ensembl_gene_id: H681_05435
symbol: AGI22967.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5007 Predicted transcriptional regulator, BolA superfamily; Belongs to the BolA/IbaG family.


ensembl_gene_id: H681_05440
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: H681_05445
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: H681_05450
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: H681_05455
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: H681_05460
symbol: AGI22972.1
gene_biotype: protein_coding
description:
  AlgW protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: H681_05475
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: H681_05480
symbol: cysC
gene_biotype: protein_coding
description:
  Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: H681_05495
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: H681_05525
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: H681_05535
symbol: AGI22987.1
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: H681_05540
symbol: AGI22988.1
gene_biotype: protein_coding
description:
  Putative cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: H681_05565
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: H681_05570
symbol: AGI22994.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: H681_05580
symbol: rsmI
gene_biotype: protein_coding
description:
  uroporphyrin-III C/tetrapyrrole methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: H681_05585
symbol: mraZ
gene_biotype: protein_coding
description:
  Cell division protein MraZ; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: H681_05590
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: H681_05595
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: H681_05600
symbol: ftsI-2
gene_biotype: protein_coding
description:
  Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: H681_05605
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: H681_05610
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: H681_05615
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: H681_05620
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: H681_05625
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: H681_05630
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: H681_05640
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: H681_05645
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: H681_05650
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: H681_05655
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: H681_05660
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: H681_05670
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: H681_05675
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: H681_05690
symbol: AGI23018.1
gene_biotype: protein_coding
description:
  cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: H681_05700
symbol: AGI23020.1
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: H681_05735
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_05750
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: H681_05755
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: H681_05760
symbol: crcB
gene_biotype: protein_coding
description:
  Chromosome condensation membrane protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: H681_05800
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: H681_05825
symbol: AGI23045.1
gene_biotype: protein_coding
description:
  Putative type II secretion system protein; COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: H681_05865
symbol: AGI23053.1
gene_biotype: protein_coding
description:
  Two-component response regulator, PprB; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_05940
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: H681_05945
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...]


ensembl_gene_id: H681_05950
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: H681_06105
symbol: AGI23101.1
gene_biotype: protein_coding
description:
  COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: H681_06175
symbol: AGI23115.1
gene_biotype: protein_coding
description:
  Ohr subfamily peroxiredoxin; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: H681_06195
symbol: AGI23119.1
gene_biotype: protein_coding
description:
  Two component winged helix family transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H681_06395
symbol: AGI23159.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: H681_06460
symbol: AGI23168.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding domain-containing protein 2; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H681_06465
symbol: AGI23169.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: H681_06470
symbol: AGI23170.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component family protein 16; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: H681_06475
symbol: AGI23171.1
gene_biotype: protein_coding
description:
  Nitrate transport ATP-binding protein NrtC domain-containing protein 2; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: H681_06525
symbol: AGI23181.1
gene_biotype: protein_coding
description:
  COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: H681_06585
symbol: AGI23193.1
gene_biotype: protein_coding
description:
  Type I toxin efflux ATP-binding protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: H681_06605
symbol: AGI23197.1
gene_biotype: protein_coding
description:
  COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family.


ensembl_gene_id: H681_06635
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: H681_06665
symbol: AGI23209.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H681_06680
symbol: AGI23212.1
gene_biotype: protein_coding
description:
  Folate-binding protein YgfZ; COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family.


ensembl_gene_id: H681_06720
symbol: AGI23220.1
gene_biotype: protein_coding
description:
  COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: H681_06725
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: H681_06740
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: H681_06745
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: H681_06755
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: H681_06760
symbol: cmoB
gene_biotype: protein_coding
description:
  tRNA mo(5)U34 methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: H681_06765
symbol: cmoA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: H681_06790
symbol: lon
gene_biotype: protein_coding
description:
  Putative ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: H681_06815
symbol: AGI23239.1
gene_biotype: protein_coding
description:
  Sodium/proline symporter PutP; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: H681_06820
symbol: sotB
gene_biotype: protein_coding
description:
  Arabinose transporter; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: H681_06830
symbol: azoR
gene_biotype: protein_coding
description:
  ACP phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: H681_06835
symbol: AGI23243.1
gene_biotype: protein_coding
description:
  Small multidrug resistance protein SugE; COG2076 Membrane transporters of cations and cationic drugs.


ensembl_gene_id: H681_06910
symbol: AGI23258.1
gene_biotype: protein_coding
description:
  Iron ABC transporter substrate-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: H681_06915
symbol: ddl-2
gene_biotype: protein_coding
description:
  D-alanyl-alanine synthetase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: H681_06930
symbol: AGI23262.1
gene_biotype: protein_coding
description:
  O-methyltransferase domain-containing protein; COG3315 O-Methyltransferase involved in polyketide biosynthesis.


ensembl_gene_id: H681_06945
symbol: AGI23265.1
gene_biotype: protein_coding
description:
  RNA polymerase ECF-subfamily sigma-70 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_06975
symbol: AGI23271.1
gene_biotype: protein_coding
description:
  COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: H681_06980
symbol: AGI23272.1
gene_biotype: protein_coding
description:
  Glutamate synthase, large subunit; COG0069 Glutamate synthase domain 2; Belongs to the glutamate synthase family.


ensembl_gene_id: H681_07025
symbol: AGI23281.1
gene_biotype: protein_coding
description:
  Putative L-carnitine dehydratase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: H681_07055
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: H681_07075
symbol: glpD
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: H681_07085
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: H681_07100
symbol: AGI23296.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_07105
symbol: AGI23297.1
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: H681_07145
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: H681_07160
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: H681_07165
symbol: AGI23309.1
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: H681_07180
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: H681_07185
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex RsxE subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: H681_07190
symbol: rnfG
gene_biotype: protein_coding
description:
  RnfABCDGE type electron transport complex subunit G; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: H681_07195
symbol: rnfD
gene_biotype: protein_coding
description:
  RnfABCDGE type electron transport complex subunit D; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: H681_07200
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: H681_07205
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: H681_07210
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex protein RsxA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: H681_07220
symbol: AGI23320.1
gene_biotype: protein_coding
description:
  CcdB antidote CcdA; COG5302 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid.


ensembl_gene_id: H681_07225
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: H681_07230
symbol: AGI23322.1
gene_biotype: protein_coding
description:
  ATP-binding Mrp/Nbp35 family protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: H681_07320
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: H681_07340
symbol: AGI23344.1
gene_biotype: protein_coding
description:
  Monovalent cation/H+ antiporter subunit A; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: H681_07410
symbol: AGI23358.1
gene_biotype: protein_coding
description:
  Alanine--glyoxylate transaminase; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H681_07415
symbol: AGI23359.1
gene_biotype: protein_coding
description:
  Aminoglycoside phosphotransferase; COG2334 Putative homoserine kinase type II (protein kinase fold).


ensembl_gene_id: H681_07420
symbol: AGI23360.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_07425
symbol: AGI23361.1
gene_biotype: protein_coding
description:
  3-oxoacyl-ACP reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_07450
symbol: AGI23366.1
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: H681_07470
symbol: AGI23370.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: H681_07475
symbol: AGI23371.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3225 ABC-type uncharacterized transport system involved in gliding motility, auxiliary component.


ensembl_gene_id: H681_07500
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: H681_07510
symbol: AGI23378.1
gene_biotype: protein_coding
description:
  ThiF family protein; COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1.


ensembl_gene_id: H681_07525
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: H681_07540
symbol: AGI23384.1
gene_biotype: protein_coding
description:
  Na(+)/H(+) exchanger protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: H681_07550
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: H681_07555
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: H681_07565
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: H681_07575
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: H681_07580
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: H681_07590
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: H681_07600
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane antigen; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: H681_07610
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: H681_07615
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: H681_07620
symbol: lpxA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: H681_07625
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: H681_07640
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: H681_07645
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: H681_07650
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: H681_07655
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.


ensembl_gene_id: H681_07660
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: H681_07665
symbol: ftsB
gene_biotype: protein_coding
description:
  Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: H681_07670
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: H681_07675
symbol: AGI23411.1
gene_biotype: protein_coding
description:
  COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: H681_07690
symbol: AGI23414.1
gene_biotype: protein_coding
description:
  COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: H681_07700
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: H681_07705
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: H681_07710
symbol: surE
gene_biotype: protein_coding
description:
  5'(3')-nucleotidase/polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: H681_07715
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: H681_07725
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: H681_07730
symbol: AGI23422.1
gene_biotype: protein_coding
description:
  Ferredoxin I; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: H681_07735
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: H681_07745
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: H681_07760
symbol: AGI23428.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: H681_07795
symbol: AGI23435.1
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: H681_07805
symbol: AGI23437.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD/NAD(P)-binding subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: H681_07835
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: H681_07840
symbol: kup
gene_biotype: protein_coding
description:
  Potassium uptake protein Kup; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: H681_07865
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: H681_07880
symbol: AGI23452.1
gene_biotype: protein_coding
description:
  COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: H681_07905
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA m(5)U1939 methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: H681_07910
symbol: AGI23458.1
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: H681_07980
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: H681_07990
symbol: AGI23474.1
gene_biotype: protein_coding
description:
  Putative 2-hydroxyacid dehydrogenase; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: H681_08020
symbol: AGI23480.1
gene_biotype: protein_coding
description:
  Putative HIT family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: H681_08035
symbol: aceK
gene_biotype: protein_coding
description:
  Bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: H681_08100
symbol: AGI23496.1
gene_biotype: protein_coding
description:
  Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: H681_08120
symbol: AGI23500.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: H681_08125
symbol: AGI23501.1
gene_biotype: protein_coding
description:
  Sodium:solute symport protein; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: H681_08130
symbol: AGI23502.1
gene_biotype: protein_coding
description:
  Cytosine/purines, uracil, thiamine, allantoin permease; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: H681_08140
symbol: AGI23504.1
gene_biotype: protein_coding
description:
  Guanidinobutyrase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: H681_08145
symbol: AGI23505.1
gene_biotype: protein_coding
description:
  Protein GbuR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H681_08185
symbol: AGI23513.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: H681_08195
symbol: AGI23515.1
gene_biotype: protein_coding
description:
  Hemolysin-type calcium-binding repeat-containing protein; COG2931 RTX toxins and related Ca2+-binding proteins.


ensembl_gene_id: H681_08225
symbol: ssuD
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: H681_08235
symbol: ssuB
gene_biotype: protein_coding
description:
  Aliphatic sulfonates transport ATP-binding subunit; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_08255
symbol: AGI23527.1
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_08275
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: H681_08290
symbol: AGI23534.1
gene_biotype: protein_coding
description:
  Morphogene protein BolA; COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.


ensembl_gene_id: H681_08355
symbol: AGI23547.1
gene_biotype: protein_coding
description:
  Aromatic amino acid transport protein AroP2; COG1113 Gamma-aminobutyrate permease and related permeases.


ensembl_gene_id: H681_08375
symbol: AGI23551.1
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: H681_08405
symbol: AGI23557.1
gene_biotype: protein_coding
description:
  GNAT family acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: H681_08495
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: H681_08570
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: H681_08580
symbol: AGI23590.1
gene_biotype: protein_coding
description:
  Lysine-arginine-ornithine-binding periplasmic protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: H681_08585
symbol: AGI23591.1
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane; COG4215 ABC-type arginine transport system, permease component.


ensembl_gene_id: H681_08590
symbol: AGI23592.1
gene_biotype: protein_coding
description:
  Arginine/ornithine transport protein AotM; COG4160 ABC-type arginine/histidine transport system, permease component.


ensembl_gene_id: H681_08600
symbol: AGI23594.1
gene_biotype: protein_coding
description:
  Arginine/ornithine transport protein AotP; COG4598 ABC-type histidine transport system, ATPase component.


ensembl_gene_id: H681_08610
symbol: argD
gene_biotype: protein_coding
description:
  Bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: H681_08625
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: H681_08630
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: H681_08640
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: H681_08650
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: H681_08660
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: H681_08695
symbol: AGI23613.1
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: H681_08705
symbol: AGI23615.1
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_08715
symbol: AGI23617.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: H681_08755
symbol: flgA
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring biosynthesis protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: H681_08770
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: H681_08780
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: H681_08800
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar basal body L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: H681_08805
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: H681_08825
symbol: AGI23639.1
gene_biotype: protein_coding
description:
  Flagellin domain-containing protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: H681_08835
symbol: AGI23641.1
gene_biotype: protein_coding
description:
  Flagellar capping protein FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: H681_08850
symbol: AGI23644.1
gene_biotype: protein_coding
description:
  Transcriptional regulator FleQ; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: H681_08875
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: H681_08880
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein G; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: H681_08920
symbol: AGI23658.1
gene_biotype: protein_coding
description:
  Antisigma-factor antagonist STAS domain-containing protein; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).


ensembl_gene_id: H681_08940
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: H681_08945
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: H681_08950
symbol: fliN
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: H681_08960
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: H681_08965
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: H681_08970
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: H681_08975
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: H681_09010
symbol: AGI23676.1
gene_biotype: protein_coding
description:
  5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: H681_09015
symbol: AGI23677.1
gene_biotype: protein_coding
description:
  Putative 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H681_09020
symbol: AGI23678.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H681_09050
symbol: AGI23684.1
gene_biotype: protein_coding
description:
  Flavin reductase domain-containing protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H681_09055
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: H681_09070
symbol: fliA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: H681_09080
symbol: AGI23690.1
gene_biotype: protein_coding
description:
  Chemotaxis protein CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: H681_09090
symbol: cheB-2
gene_biotype: protein_coding
description:
  Chemotaxis-specific protein-glutamate methyltransferase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: H681_09130
symbol: AGI23700.1
gene_biotype: protein_coding
description:
  Type III secretion exporter; COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.


ensembl_gene_id: H681_09140
symbol: ccmA
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: H681_09145
symbol: AGI23703.1
gene_biotype: protein_coding
description:
  Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: H681_09150
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: H681_09155
symbol: AGI23705.1
gene_biotype: protein_coding
description:
  Heme exporter protein CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: H681_09160
symbol: ccmE
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: H681_09200
symbol: AGI23714.1
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein KefB; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: H681_09210
symbol: AGI23716.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases.


ensembl_gene_id: H681_09230
symbol: AGI23720.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H681_09290
symbol: AGI23732.1
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: H681_09330
symbol: AGI23740.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: H681_09365
symbol: AGI23747.1
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: H681_09370
symbol: AGI23748.1
gene_biotype: protein_coding
description:
  Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: H681_09385
symbol: AGI23751.1
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter periplasmic molybdate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: H681_09390
symbol: AGI23752.1
gene_biotype: protein_coding
description:
  Molybdenum transport protein ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: H681_09395
symbol: modC
gene_biotype: protein_coding
description:
  Molybdenum transport ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: H681_09405
symbol: AGI23755.1
gene_biotype: protein_coding
description:
  COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: H681_09445
symbol: dctA
gene_biotype: protein_coding
description:
  C4-dicarboxylate transporter DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: H681_09450
symbol: AGI23764.1
gene_biotype: protein_coding
description:
  Putative adenylate/guanylate cyclase; COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain).


ensembl_gene_id: H681_09465
symbol: AGI23767.1
gene_biotype: protein_coding
description:
  Sulfate-binding protein of ABC transporter; COG1613 ABC-type sulfate transport system, periplasmic component.


ensembl_gene_id: H681_09470
symbol: sstT
gene_biotype: protein_coding
description:
  Serine/threonine transporter SstT; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: H681_09495
symbol: AGI23773.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: H681_09520
symbol: moaA-2
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: H681_09575
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: H681_09580
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: H681_09590
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: H681_09595
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: H681_09600
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA ligase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: H681_09605
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: H681_09615
symbol: AGI23797.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_09625
symbol: AGI23799.1
gene_biotype: protein_coding
description:
  MhpD protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H681_09635
symbol: AGI23801.1
gene_biotype: protein_coding
description:
  2,4-dichlorophenol 6-monooxygenase TfdB; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H681_09695
symbol: AGI23813.1
gene_biotype: protein_coding
description:
  Putative conjugal transfer TrbD transmembrane protein; COG5268 Type IV secretory pathway, TrbD component.


ensembl_gene_id: H681_09770
symbol: AGI23828.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain-containing protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: H681_09775
symbol: AGI23829.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: H681_09900
symbol: AGI23854.1
gene_biotype: protein_coding
description:
  Tyrosine-based site-specific recombinase CMGI-2; COG0582 Integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: H681_09905
symbol: AGI23855.1
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: H681_09910
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-(acyl carrier protein) dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: H681_09920
symbol: AGI23858.1
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG2984 ABC-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: H681_09930
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: H681_09955
symbol: AGI23865.1
gene_biotype: protein_coding
description:
  4-hydroxybenzoyl-CoA thioesterase domain-containing protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: H681_10005
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: H681_10010
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: H681_10015
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: H681_10040
symbol: selU
gene_biotype: protein_coding
description:
  tRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: H681_10060
symbol: tpx
gene_biotype: protein_coding
description:
  Lipid hydroperoxide peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: H681_10070
symbol: AGI23888.1
gene_biotype: protein_coding
description:
  Resistance-Nodulation-Cell Division (RND) efflux transporter; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: H681_10075
symbol: AGI23889.1
gene_biotype: protein_coding
description:
  COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: H681_10085
symbol: AGI23891.1
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: H681_10125
symbol: AGI23899.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG3300 MHYT domain (predicted integral membrane sensor domain).


ensembl_gene_id: H681_10170
symbol: AGI23908.1
gene_biotype: protein_coding
description:
  RND multidrug efflux membrane fusion protein MexE; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_10195
symbol: AGI23913.1
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: H681_10260
symbol: AGI23926.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms; Belongs to the hemerythrin family.


ensembl_gene_id: H681_10290
symbol: prmB
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: H681_10305
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: H681_10320
symbol: mtnB
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: H681_10325
symbol: mtnD
gene_biotype: protein_coding
description:
  Putative oxidase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: H681_10330
symbol: mtnC
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: H681_10335
symbol: AGI23939.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: H681_10345
symbol: AGI23941.1
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: H681_10350
symbol: AGI23942.1
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosidase II; COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase.


ensembl_gene_id: H681_10355
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: H681_10360
symbol: AGI23944.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.


ensembl_gene_id: H681_10415
symbol: AGI23955.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: H681_10420
symbol: AGI23956.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: H681_10425
symbol: AGI23957.1
gene_biotype: protein_coding
description:
  COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_10480
symbol: AGI23968.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: H681_10585
symbol: AGI23989.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.


ensembl_gene_id: H681_10625
symbol: AGI23997.1
gene_biotype: protein_coding
description:
  PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: H681_10635
symbol: AGI23999.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: H681_10645
symbol: AGI24001.1
gene_biotype: protein_coding
description:
  Ribonuclease activity regulator protein RraA; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: H681_10670
symbol: AGI24006.1
gene_biotype: protein_coding
description:
  Major porin and structural outer membrane porin OprF precursor; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: H681_10675
symbol: AGI24007.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: H681_10680
symbol: AGI24008.1
gene_biotype: protein_coding
description:
  Assimilatory nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: H681_10690
symbol: AGI24010.1
gene_biotype: protein_coding
description:
  Assimilatory nitrite reductase large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: H681_10720
symbol: AGI24016.1
gene_biotype: protein_coding
description:
  Nitrate-binding protein NasS; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: H681_10725
symbol: AGI24017.1
gene_biotype: protein_coding
description:
  Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; COG1049 Aconitase B; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: H681_10750
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: H681_10755
symbol: AGI24023.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: H681_10770
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: H681_10775
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: H681_10780
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: H681_10785
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: H681_10790
symbol: lon-2
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: H681_10795
symbol: AGI24031.1
gene_biotype: protein_coding
description:
  DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: H681_10810
symbol: AGI24034.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_10825
symbol: AGI24037.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: H681_10835
symbol: AGI24039.1
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: H681_10840
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: H681_10855
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: H681_10890
symbol: nudC
gene_biotype: protein_coding
description:
  NADH pyrophosphatase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family. NudC subfamily.


ensembl_gene_id: H681_10970
symbol: AGI24064.1
gene_biotype: protein_coding
description:
  multidrug/Oligosaccharidyl-lipid/Polysaccharide flippase superfamily protein; COG0534 Na+-driven multidrug efflux pump.


ensembl_gene_id: H681_10980
symbol: metH
gene_biotype: protein_coding
description:
  B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: H681_10990
symbol: nfuA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: H681_11010
symbol: AGI24072.1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: H681_11030
symbol: AGI24076.1
gene_biotype: protein_coding
description:
  Phenylacetic acid degradation-related protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: H681_11040
symbol: AGI24078.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: H681_11050
symbol: AGI24080.1
gene_biotype: protein_coding
description:
  Fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; COG3573 Predicted oxidoreductase.


ensembl_gene_id: H681_11070
symbol: AGI24084.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: H681_11075
symbol: AGI24085.1
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H681_11085
symbol: AGI24087.1
gene_biotype: protein_coding
description:
  Pca operon transcription factor PcaQ; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H681_11130
symbol: AGI24096.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: H681_11155
symbol: AGI24101.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: H681_11165
symbol: putA
gene_biotype: protein_coding
description:
  Trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: H681_11195
symbol: AGI24109.1
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: H681_11235
symbol: AGI24117.1
gene_biotype: protein_coding
description:
  Flavin-dependent oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: H681_11255
symbol: AGI24121.1
gene_biotype: protein_coding
description:
  TonB-dependent hemoglobin/transferrin/lactoferrin receptor; COG1629 Outer membrane receptor proteins, mostly Fe transport.


ensembl_gene_id: H681_11265
symbol: AGI24123.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_11290
symbol: phnW
gene_biotype: protein_coding
description:
  2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.


ensembl_gene_id: H681_11295
symbol: phnX
gene_biotype: protein_coding
description:
  Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family.


ensembl_gene_id: H681_11315
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: H681_11350
symbol: AGI24140.1
gene_biotype: protein_coding
description:
  Benzoate dioxygenase subunit alpha; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: H681_11360
symbol: AGI24142.1
gene_biotype: protein_coding
description:
  Oxidoreductase, FAD/NAD(P)-binding subunit; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: H681_11365
symbol: benD
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_11370
symbol: AGI24144.1
gene_biotype: protein_coding
description:
  Muconate cycloisomerase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: H681_11395
symbol: AGI24149.1
gene_biotype: protein_coding
description:
  Beta-ketoadipyl CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: H681_11405
symbol: AGI24151.1
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactonase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_11450
symbol: AGI24160.1
gene_biotype: protein_coding
description:
  Fis family transcriptional regulator; COG3284 Transcriptional activator of acetoin/glycerol metabolism.


ensembl_gene_id: H681_11455
symbol: AGI24161.1
gene_biotype: protein_coding
description:
  ABC transporter transmembrane protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H681_11485
symbol: AGI24167.1
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: H681_11530
symbol: AGI24176.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein/permease; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: H681_11540
symbol: AGI24178.1
gene_biotype: protein_coding
description:
  OmpA-like transmembrane domain protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: H681_11645
symbol: AGI24199.1
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_11650
symbol: AGI24200.1
gene_biotype: protein_coding
description:
  acyl-CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: H681_11690
symbol: AGI24208.1
gene_biotype: protein_coding
description:
  LuxR family two component transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_11720
symbol: AGI24214.1
gene_biotype: protein_coding
description:
  Oxidoreductase iron sulfur binding subunit; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: H681_11725
symbol: AGI24215.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: H681_11740
symbol: AGI24218.1
gene_biotype: protein_coding
description:
  DSBA oxidoreductase; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: H681_11765
symbol: AGI24223.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: H681_11775
symbol: AGI24225.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: H681_11845
symbol: AGI24239.1
gene_biotype: protein_coding
description:
  Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.


ensembl_gene_id: H681_11850
symbol: AGI24240.1
gene_biotype: protein_coding
description:
  Two component heavy metal response transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H681_11860
symbol: AGI24242.1
gene_biotype: protein_coding
description:
  Cation efflux family protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_11865
symbol: AGI24243.1
gene_biotype: protein_coding
description:
  Cobalt/zinc/cadmium resistance protein CzcA; COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: H681_11900
symbol: AGI24250.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.


ensembl_gene_id: H681_11915
symbol: dkgB
gene_biotype: protein_coding
description:
  2,5-diketo-D-gluconate reductase B; COG0656 Aldo/keto reductases, related to diketogulonate reductase.


ensembl_gene_id: H681_11975
symbol: AGI24265.1
gene_biotype: protein_coding
description:
  Periplasmic polyamine-binding protein, putative; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_12020
symbol: AGI24274.1
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: H681_12035
symbol: AGI24277.1
gene_biotype: protein_coding
description:
  Arsenical pump membrane protein; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.


ensembl_gene_id: H681_12115
symbol: AGI24293.1
gene_biotype: protein_coding
description:
  Hemagglutination activity domain protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: H681_12120
symbol: AGI24294.1
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_12140
symbol: AGI24298.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: H681_12150
symbol: AGI24300.1
gene_biotype: protein_coding
description:
  Von Willebrand factor type A; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.


ensembl_gene_id: H681_12260
symbol: AGI24322.1
gene_biotype: protein_coding
description:
  CaiB/BaiF family protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: H681_12265
symbol: AGI24323.1
gene_biotype: protein_coding
description:
  HpcH/HpaI aldolase/citrate lyase; COG2301 Citrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family.


ensembl_gene_id: H681_12270
symbol: AGI24324.1
gene_biotype: protein_coding
description:
  Lipid-transfer protein; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: H681_12300
symbol: AGI24330.1
gene_biotype: protein_coding
description:
  L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: H681_12360
symbol: AGI24342.1
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: H681_12480
symbol: AGI24366.1
gene_biotype: protein_coding
description:
  Putative restriction endonuclease; COG1787 Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes.


ensembl_gene_id: H681_12585
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: H681_12605
symbol: AGI24391.1
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_12615
symbol: AGI24393.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: H681_12630
symbol: AGI24396.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-70 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_12665
symbol: AGI24403.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA.


ensembl_gene_id: H681_12710
symbol: AGI24412.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: H681_12740
symbol: AGI24418.1
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: H681_12785
symbol: AGI24427.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein/permease PltK; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: H681_12815
symbol: AGI24433.1
gene_biotype: protein_coding
description:
  Methyltransferase; COG1092 Predicted SAM-dependent methyltransferases; Belongs to the methyltransferase superfamily.


ensembl_gene_id: H681_12820
symbol: AGI24434.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: H681_12840
symbol: dnaE2
gene_biotype: protein_coding
description:
  Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: H681_12855
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: H681_12890
symbol: AGI24448.1
gene_biotype: protein_coding
description:
  Extracytoplasmic-function sigma-70 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_12935
symbol: AGI24457.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_13005
symbol: AGI24471.1
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase subunit alpha; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: H681_13010
symbol: AGI24472.1
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase subunit beta; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: H681_13015
symbol: AGI24473.1
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: H681_13025
symbol: AGI24475.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: H681_13035
symbol: AGI24477.1
gene_biotype: protein_coding
description:
  Putative sodium/solute symporter; COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: H681_13045
symbol: AGI24479.1
gene_biotype: protein_coding
description:
  Siderophore biosynthesis protein; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: H681_13065
symbol: AGI24483.1
gene_biotype: protein_coding
description:
  Cyclic peptide transporter; COG4615 ABC-type siderophore export system, fused ATPase and permease components.


ensembl_gene_id: H681_13075
symbol: AGI24485.1
gene_biotype: protein_coding
description:
  Fe3+-siderophore ABC transporter periplasmic solute-binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: H681_13080
symbol: AGI24486.1
gene_biotype: protein_coding
description:
  Iron-hydroxamate transporter permease subunit; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H681_13115
symbol: hmgA
gene_biotype: protein_coding
description:
  Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.


ensembl_gene_id: H681_13120
symbol: AGI24494.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H681_13200
symbol: AGI24510.1
gene_biotype: protein_coding
description:
  Sigma-24 (FecI); COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_13205
symbol: AGI24511.1
gene_biotype: protein_coding
description:
  Transmembrane regulator PrtR; COG5662 Predicted transmembrane transcriptional regulator (anti-sigma factor).


ensembl_gene_id: H681_13295
symbol: azoR-2
gene_biotype: protein_coding
description:
  Azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: H681_13310
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: H681_13320
symbol: AGI24534.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: H681_13340
symbol: AGI24538.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: H681_13410
symbol: AGI24552.1
gene_biotype: protein_coding
description:
  Family 1 extracellular solute-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_13415
symbol: AGI24553.1
gene_biotype: protein_coding
description:
  Aldolase II superfamily protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: H681_13495
symbol: AGI24569.1
gene_biotype: protein_coding
description:
  Glutathione reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: H681_13510
symbol: AGI24572.1
gene_biotype: protein_coding
description:
  Peptidase S24 and S26 domain-containing protein; COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Belongs to the peptidase S24 family.


ensembl_gene_id: H681_13520
symbol: AGI24574.1
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_13550
symbol: AGI24580.1
gene_biotype: protein_coding
description:
  Putative two-component system sensor kinase; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_13555
symbol: AGI24581.1
gene_biotype: protein_coding
description:
  Putative two-component system sensor kinase; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_13565
symbol: AGI24583.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H681_13570
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: H681_13590
symbol: AGI24588.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction.


ensembl_gene_id: H681_13595
symbol: AGI24589.1
gene_biotype: protein_coding
description:
  Sulfur relay protein TusC; COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur; Belongs to the DsrF/TusC family.


ensembl_gene_id: H681_13600
symbol: AGI24590.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2168 Uncharacterized conserved protein involved in oxidation of intracellular sulfur.


ensembl_gene_id: H681_13625
symbol: cysG
gene_biotype: protein_coding
description:
  Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: H681_13630
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: H681_13635
symbol: AGI24597.1
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: H681_13640
symbol: lolA
gene_biotype: protein_coding
description:
  Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: H681_13655
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: H681_13660
symbol: bpt
gene_biotype: protein_coding
description:
  arginyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: H681_13665
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: H681_13670
symbol: AGI24604.1
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpA; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: H681_13675
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: H681_13700
symbol: nudJ
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: H681_13705
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: H681_13750
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: H681_13755
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H681_13760
symbol: nuoC
gene_biotype: protein_coding
description:
  Bifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: H681_13770
symbol: AGI24624.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: H681_13775
symbol: AGI24625.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: H681_13780
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: H681_13785
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H681_13790
symbol: AGI24628.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: H681_13795
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: H681_13800
symbol: AGI24630.1
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: H681_13810
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: H681_13865
symbol: hmp
gene_biotype: protein_coding
description:
  Bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: H681_13870
symbol: AGI24644.1
gene_biotype: protein_coding
description:
  Anaerobic nitric oxide reductase transcription regulator; COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains.


ensembl_gene_id: H681_13940
symbol: AGI24658.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: H681_13945
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: H681_13950
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: H681_13960
symbol: AGI24662.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: H681_13975
symbol: sdhA
gene_biotype: protein_coding
description:
  COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: H681_13980
symbol: AGI24666.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: H681_14020
symbol: ppnP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: H681_14160
symbol: AGI24702.1
gene_biotype: protein_coding
description:
  Putative peptidyl-arginine deiminase; COG2957 Peptidylarginine deiminase and related enzymes; Belongs to the agmatine deiminase family.


ensembl_gene_id: H681_14165
symbol: AGI24703.1
gene_biotype: protein_coding
description:
  Polyamine ABC transporter substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_14195
symbol: AGI24709.1
gene_biotype: protein_coding
description:
  Alpha,alpha-trehalose-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.


ensembl_gene_id: H681_14255
symbol: AGI24721.1
gene_biotype: protein_coding
description:
  Aldo/keto reductase 2 family oxidoreductase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: H681_14265
symbol: AGI24723.1
gene_biotype: protein_coding
description:
  Putative Pyridoxine 4-dehydrogenase; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).


ensembl_gene_id: H681_14285
symbol: narG
gene_biotype: protein_coding
description:
  COG5013 Nitrate reductase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: H681_14400
symbol: AGI24750.1
gene_biotype: protein_coding
description:
  Secretion protein HlyD; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_14425
symbol: AGI24755.1
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; COG0820 Predicted Fe-S-cluster redox enzyme; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: H681_14430
symbol: ampC
gene_biotype: protein_coding
description:
  beta-lactamase/D-alanine carboxypeptidase; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: H681_14460
symbol: AGI24762.1
gene_biotype: protein_coding
description:
  Aromatic hydrocarbons catabolism-related reductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: H681_14490
symbol: AGI24768.1
gene_biotype: protein_coding
description:
  COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: H681_14495
symbol: AGI24769.1
gene_biotype: protein_coding
description:
  Transcriptional Regulator, LysR family; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H681_14545
symbol: phnC
gene_biotype: protein_coding
description:
  Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: H681_14550
symbol: AGI24780.1
gene_biotype: protein_coding
description:
  Phosphonate ABC transporter inner membrane subunit; COG3639 ABC-type phosphate/phosphonate transport system, permease component.


ensembl_gene_id: H681_14555
symbol: AGI24781.1
gene_biotype: protein_coding
description:
  Phosphonate metabolism-associated iron-containing alcohol dehydrogenase; COG1454 Alcohol dehydrogenase, class IV.


ensembl_gene_id: H681_14660
symbol: AGI24802.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate-binding protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: H681_14680
symbol: AGI24806.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_14720
symbol: AGI24814.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_14825
symbol: AGI24835.1
gene_biotype: protein_coding
description:
  CzcA family heavy metal efflux protein; COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: H681_14830
symbol: AGI24836.1
gene_biotype: protein_coding
description:
  CzcB family heavy metal RND efflux membrane fusion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_14995
symbol: AGI24867.1
gene_biotype: protein_coding
description:
  mutT/nudix family protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: H681_15020
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: H681_15025
symbol: AGI24873.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: H681_15080
symbol: potA-2
gene_biotype: protein_coding
description:
  Polyamine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_15085
symbol: AGI24885.1
gene_biotype: protein_coding
description:
  Polyamine/opine/phosphonate ABC transporter, POPT family, periplasmic substrate-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_15100
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfur transfer protein SirA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: H681_15115
symbol: rlmM
gene_biotype: protein_coding
description:
  23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: H681_15130
symbol: AGI24894.1
gene_biotype: protein_coding
description:
  COG3278 Cbb3-type cytochrome oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: H681_15165
symbol: AGI24901.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase cbb3-type subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: H681_15185
symbol: AGI24905.1
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome oxidase maturation protein; COG3197 Uncharacterized protein, possibly involved in nitrogen fixation.


ensembl_gene_id: H681_15205
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: H681_15250
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: H681_15255
symbol: AGI24919.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: H681_15260
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: H681_15300
symbol: AGI24928.1
gene_biotype: protein_coding
description:
  COG0776 Bacterial nucleoid DNA-binding protein; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: H681_15305
symbol: ligA
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: H681_15310
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: H681_15315
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: H681_15340
symbol: AGI24936.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor sulfurylase; COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family.


ensembl_gene_id: H681_15345
symbol: AGI24937.1
gene_biotype: protein_coding
description:
  Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: H681_15400
symbol: AGI24948.1
gene_biotype: protein_coding
description:
  Virulence sensor protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_15405
symbol: AGI24949.1
gene_biotype: protein_coding
description:
  Hydroxyisourate hydrolase; COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: H681_15420
symbol: allA
gene_biotype: protein_coding
description:
  Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.


ensembl_gene_id: H681_15440
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: H681_15445
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: H681_15485
symbol: queF
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: H681_15505
symbol: AGI24969.1
gene_biotype: protein_coding
description:
  Two-component response regulator, CopR; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: H681_15610
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: H681_15625
symbol: htpX
gene_biotype: protein_coding
description:
  Heat shock protein HtpX; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: H681_15630
symbol: tpm
gene_biotype: protein_coding
description:
  Thiopurine S-methyltransferase; COG0500 SAM-dependent methyltransferases; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: H681_15645
symbol: deaD
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: H681_15675
symbol: AGI25003.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.


ensembl_gene_id: H681_15705
symbol: AGI25009.1
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: H681_15710
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: H681_15740
symbol: AGI25016.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: H681_15745
symbol: AGI25017.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component.


ensembl_gene_id: H681_15750
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: H681_15760
symbol: AGI25020.1
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: H681_15780
symbol: AGI25024.1
gene_biotype: protein_coding
description:
  Slt family transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: H681_15835
symbol: AGI25035.1
gene_biotype: protein_coding
description:
  Regulatory protein LysR; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H681_15845
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: H681_15875
symbol: AGI25043.1
gene_biotype: protein_coding
description:
  Putative biotin-dependent carboxylase; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).


ensembl_gene_id: H681_15945
symbol: AGI25057.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_15950
symbol: AGI25058.1
gene_biotype: protein_coding
description:
  Putative lipase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_15955
symbol: fabV
gene_biotype: protein_coding
description:
  trans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: H681_15970
symbol: AGI25062.1
gene_biotype: protein_coding
description:
  Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: H681_15990
symbol: AGI25066.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain-containing protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: H681_16020
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: H681_16025
symbol: mltG
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: H681_16030
symbol: AGI25074.1
gene_biotype: protein_coding
description:
  4-amino-4-deoxychorismate lyase; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: H681_16035
symbol: AGI25075.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: H681_16045
symbol: fabG-2
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_16055
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: H681_16070
symbol: AGI25082.1
gene_biotype: protein_coding
description:
  Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: H681_16085
symbol: AGI25085.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: H681_16090
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: H681_16105
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: H681_16115
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: H681_16130
symbol: AGI25094.1
gene_biotype: protein_coding
description:
  DNA internalization-related competence protein ComEC/Rec2; COG0658 Predicted membrane metal-binding protein.


ensembl_gene_id: H681_16140
symbol: AGI25096.1
gene_biotype: protein_coding
description:
  Lipoprotein releasing system transmembrane protein LolC/E family; COG4591 ABC-type transport system, involved in lipoprotein release, permease component.


ensembl_gene_id: H681_16145
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein transporter ATP-binding subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: H681_16150
symbol: AGI25098.1
gene_biotype: protein_coding
description:
  LolC/E family lipoprotein releasing system, transmembrane protein; COG4591 ABC-type transport system, involved in lipoprotein release, permease component.


ensembl_gene_id: H681_16170
symbol: sthA
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: H681_16175
symbol: AGI25103.1
gene_biotype: protein_coding
description:
  ApbE-like lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: H681_16185
symbol: AGI25105.1
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: H681_16190
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: H681_16205
symbol: AGI25109.1
gene_biotype: protein_coding
description:
  5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.


ensembl_gene_id: H681_16210
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: H681_16225
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: H681_16230
symbol: AGI25114.1
gene_biotype: protein_coding
description:
  Cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: H681_16245
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...]


ensembl_gene_id: H681_16255
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: H681_16260
symbol: fadB
gene_biotype: protein_coding
description:
  Multifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: H681_16310
symbol: AGI25130.1
gene_biotype: protein_coding
description:
  Lipid kinase; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.


ensembl_gene_id: H681_16335
symbol: AGI25135.1
gene_biotype: protein_coding
description:
  Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: H681_16340
symbol: AGI25136.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthetic protein B2; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: H681_16345
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: H681_16370
symbol: AGI25142.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: H681_16405
symbol: AGI25149.1
gene_biotype: protein_coding
description:
  Diguanylate phosphodiesterase; COG4943 Predicted signal transduction protein containing sensor and EAL domains.


ensembl_gene_id: H681_16450
symbol: rlmL
gene_biotype: protein_coding
description:
  23S rRNA m(2)G2445 methyltransferase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: H681_16455
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: H681_16460
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: H681_16515
symbol: AGI25171.1
gene_biotype: protein_coding
description:
  Binding protein component of ABC transporter; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_16565
symbol: AGI25181.1
gene_biotype: protein_coding
description:
  BNR/Asp-box repeat-containing protein; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: H681_16600
symbol: AGI25188.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: H681_16605
symbol: ppnK
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: H681_16640
symbol: AGI25196.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_16645
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: H681_16650
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: H681_16670
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: H681_16680
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: H681_16690
symbol: AGI25206.1
gene_biotype: protein_coding
description:
  COG0136 Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: H681_16700
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: H681_16705
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: H681_16715
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: H681_16720
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: H681_16755
symbol: AGI25219.1
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: H681_16765
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: H681_16790
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: H681_16810
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: H681_16825
symbol: AGI25233.1
gene_biotype: protein_coding
description:
  Nucleotide sugar epimerase/dehydratase WbpM; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: H681_16830
symbol: AGI25234.1
gene_biotype: protein_coding
description:
  Glycosyltransferase WbpL; COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase.


ensembl_gene_id: H681_16850
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: H681_16855
symbol: azoR-3
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: H681_16875
symbol: AGI25243.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase A; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: H681_16880
symbol: AGI25244.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein/permease; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: H681_16895
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: H681_16905
symbol: AGI25249.1
gene_biotype: protein_coding
description:
  Aldose 1-epimerase; COG0676 Uncharacterized enzymes related to aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family.


ensembl_gene_id: H681_16915
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: H681_16930
symbol: AGI25254.1
gene_biotype: protein_coding
description:
  beta-D-glucoside glucohydrolase; COG1472 Beta-glucosidase-related glycosidases; Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: H681_16935
symbol: AGI25255.1
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: H681_16945
symbol: AGI25257.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: H681_16965
symbol: AGI25261.1
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: H681_16985
symbol: AGI25265.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein.


ensembl_gene_id: H681_17005
symbol: AGI25269.1
gene_biotype: protein_coding
description:
  Potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: H681_17090
symbol: AGI25286.1
gene_biotype: protein_coding
description:
  Putative type II secretion protein; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: H681_17095
symbol: AGI25287.1
gene_biotype: protein_coding
description:
  ABC-2 transporter permease; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: H681_17105
symbol: aroA
gene_biotype: protein_coding
description:
  Bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: H681_17120
symbol: serC
gene_biotype: protein_coding
description:
  3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: H681_17125
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: H681_17130
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: H681_17135
symbol: mtaD
gene_biotype: protein_coding
description:
  N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.


ensembl_gene_id: H681_17140
symbol: ubiG
gene_biotype: protein_coding
description:
  Bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: H681_17150
symbol: AGI25298.1
gene_biotype: protein_coding
description:
  Oxoacyl-(acyl carrier protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_17160
symbol: AGI25300.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: H681_17220
symbol: hldD
gene_biotype: protein_coding
description:
  ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: H681_17260
symbol: AGI25320.1
gene_biotype: protein_coding
description:
  COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; Belongs to the UPF0149 family.


ensembl_gene_id: H681_17280
symbol: AGI25324.1
gene_biotype: protein_coding
description:
  Multidrug ABC transporter; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: H681_17285
symbol: AGI25325.1
gene_biotype: protein_coding
description:
  Resistance-Nodulation-cell Division (RND) efflux membrane fusion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_17305
symbol: mnmC
gene_biotype: protein_coding
description:
  Bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: H681_17365
symbol: AGI25341.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains.


ensembl_gene_id: H681_17370
symbol: actP
gene_biotype: protein_coding
description:
  Acetate permease; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: H681_17380
symbol: AGI25344.1
gene_biotype: protein_coding
description:
  Glycine betaine-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: H681_17430
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: H681_17435
symbol: minC
gene_biotype: protein_coding
description:
  Septum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: H681_17445
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: H681_17450
symbol: AGI25358.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase A; COG0564 Pseudouridylate synthases, 23S RNA-specific.


ensembl_gene_id: H681_17470
symbol: AGI25362.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: H681_17480
symbol: AGI25364.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport system inner membrane protein; COG4132 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: H681_17500
symbol: AGI25368.1
gene_biotype: protein_coding
description:
  Peptidase M50, membrane-associated zinc metallopeptidase; COG0750 Predicted membrane-associated Zn-dependent proteases 1.


ensembl_gene_id: H681_17535
symbol: AGI25375.1
gene_biotype: protein_coding
description:
  Putative periplasmic binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_17615
symbol: AGI25391.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_17640
symbol: AGI25396.1
gene_biotype: protein_coding
description:
  XRE family transcriptional regulator; COG1813 Predicted transcription factor, homolog of eukaryotic MBF1.


ensembl_gene_id: H681_17650
symbol: AGI25398.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: H681_17670
symbol: AGI25402.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: H681_17705
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: H681_17720
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: H681_17745
symbol: AGI25416.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: H681_17755
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: H681_17760
symbol: queC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: H681_17765
symbol: queE
gene_biotype: protein_coding
description:
  Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: H681_17770
symbol: cpoB
gene_biotype: protein_coding
description:
  Tol-pal system protein YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: H681_17775
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: H681_17780
symbol: tolB
gene_biotype: protein_coding
description:
  Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: H681_17790
symbol: tolR
gene_biotype: protein_coding
description:
  Biopolymer transport protein ExbD/TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: H681_17795
symbol: tolQ
gene_biotype: protein_coding
description:
  TolQ protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: H681_17805
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: H681_17810
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: H681_17815
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: H681_17825
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: H681_17835
symbol: AGI25434.1
gene_biotype: protein_coding
description:
  Ferritin, Dps family protein; COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family.


ensembl_gene_id: H681_17850
symbol: AGI25437.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: H681_17865
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyla [...]


ensembl_gene_id: H681_17935
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: H681_17970
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: H681_17980
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: H681_17985
symbol: cobU
gene_biotype: protein_coding
description:
  Adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: H681_17990
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: H681_17995
symbol: AGI25466.1
gene_biotype: protein_coding
description:
  Threonine-phosphate decarboxylase; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: H681_18000
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: H681_18010
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: H681_18015
symbol: AGI25470.1
gene_biotype: protein_coding
description:
  cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: H681_18030
symbol: AGI25473.1
gene_biotype: protein_coding
description:
  Putative ABC transporter permease; COG0767 ABC-type transport system involved in resistance to organic solvents, permease component.


ensembl_gene_id: H681_18040
symbol: AGI25475.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: H681_18070
symbol: AGI25481.1
gene_biotype: protein_coding
description:
  Cystine transporter subunit; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: H681_18080
symbol: AGI25483.1
gene_biotype: protein_coding
description:
  Amino-acid ABC transporter ATP-binding protein YecC; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: H681_18115
symbol: ttcA
gene_biotype: protein_coding
description:
  tRNA 2-thiocytidine biosynthesis protein TtcA; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: H681_18135
symbol: AGI25494.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: H681_18165
symbol: AGI25500.1
gene_biotype: protein_coding
description:
  Putative sigma-70 factor, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: H681_18240
symbol: AGI25515.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_18275
symbol: rapA
gene_biotype: protein_coding
description:
  ATP-dependent helicase HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: H681_18310
symbol: phnC-2
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: H681_18315
symbol: AGI25530.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG3639 ABC-type phosphate/phosphonate transport system, permease component.


ensembl_gene_id: H681_18335
symbol: AGI25534.1
gene_biotype: protein_coding
description:
  Leucine ABC transporter subunit substrate-binding protein LivK; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: H681_18340
symbol: AGI25535.1
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H681_18345
symbol: livM
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter permease subunit; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H681_18350
symbol: livG
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter ATP-binding subunit; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: H681_18355
symbol: AGI25538.1
gene_biotype: protein_coding
description:
  High-affinity amino acid ABC transporter ATP-binding protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_18360
symbol: AGI25539.1
gene_biotype: protein_coding
description:
  RND efflux transporter; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: H681_18365
symbol: AGI25540.1
gene_biotype: protein_coding
description:
  Putative efflux transmembrane protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_18395
symbol: AGI25546.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: H681_18400
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: H681_18405
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: H681_18465
symbol: AGI25560.1
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: H681_18560
symbol: AGI25579.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: H681_18580
symbol: AGI25583.1
gene_biotype: protein_coding
description:
  COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: H681_18590
symbol: AGI25585.1
gene_biotype: protein_coding
description:
  CoA-transferase; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: H681_18640
symbol: AGI25595.1
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: H681_18645
symbol: xerD
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: H681_18650
symbol: AGI25597.1
gene_biotype: protein_coding
description:
  Putative sodium/hydrogen antiporter; COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: H681_18655
symbol: AGI25598.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB.


ensembl_gene_id: H681_18665
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: H681_18670
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: H681_18675
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: H681_18685
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...]


ensembl_gene_id: H681_18710
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: H681_18750
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: H681_18755
symbol: mltF
gene_biotype: protein_coding
description:
  Membrane-bound lytic transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: H681_18760
symbol: tadA
gene_biotype: protein_coding
description:
  Cytosine/adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: H681_18775
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: H681_18780
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: H681_18785
symbol: ddpX
gene_biotype: protein_coding
description:
  Peptidase M15D, VanX D-ala-D-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.


ensembl_gene_id: H681_18825
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: H681_18860
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: H681_18865
symbol: bamB
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: H681_18880
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: H681_18895
symbol: rlmN
gene_biotype: protein_coding
description:
  Putative Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: H681_18900
symbol: ndk
gene_biotype: protein_coding
description:
  Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: H681_18915
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: H681_18920
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: H681_18925
symbol: AGI25652.1
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: H681_18930
symbol: AGI25653.1
gene_biotype: protein_coding
description:
  Scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: H681_18935
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: H681_18940
symbol: AGI25655.1
gene_biotype: protein_coding
description:
  Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: H681_18950
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: H681_18955
symbol: AGI25658.1
gene_biotype: protein_coding
description:
  Extragenic suppressor protein SuhB; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: H681_18965
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: H681_18970
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: H681_18975
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: H681_18980
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: H681_18985
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: H681_19040
symbol: pepA
gene_biotype: protein_coding
description:
  Multifunctional aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: H681_19055
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: H681_19065
symbol: AGI25680.1
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: H681_19085
symbol: rlmF
gene_biotype: protein_coding
description:
  23S rRNA mA1618 methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA.


ensembl_gene_id: H681_19120
symbol: AGI25691.1
gene_biotype: protein_coding
description:
  Aminoglycoside N6'-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: H681_19135
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease subunit SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: H681_19180
symbol: AGI25703.1
gene_biotype: protein_coding
description:
  Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H681_19190
symbol: AGI25705.1
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: H681_19200
symbol: AGI25707.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: H681_19210
symbol: AGI25709.1
gene_biotype: protein_coding
description:
  Heme d1 biosynthesis protein NirJ; COG0535 Predicted Fe-S oxidoreductases; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: H681_19270
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: H681_19280
symbol: AGI25723.1
gene_biotype: protein_coding
description:
  FAD-dependent catabolic D-arginine dehydrogenase, DauA; COG0665 Glycine/D-amino acid oxidases (deaminating).


ensembl_gene_id: H681_19340
symbol: AGI25735.1
gene_biotype: protein_coding
description:
  Transcriptional regulator NarL; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_19365
symbol: AGI25740.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthetic protein A1; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: H681_19370
symbol: AGI25741.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthetic protein B1; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: H681_19390
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: H681_19395
symbol: AGI25746.1
gene_biotype: protein_coding
description:
  PhoH family protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: H681_19405
symbol: AGI25748.1
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: H681_19425
symbol: AGI25752.1
gene_biotype: protein_coding
description:
  COG1004 Predicted UDP-glucose 6-dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: H681_19430
symbol: AGI25753.1
gene_biotype: protein_coding
description:
  Alginate biosynthesis protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.


ensembl_gene_id: H681_19460
symbol: algL
gene_biotype: protein_coding
description:
  poly(beta-D-mannuronate) lyase; Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism; Belongs to the polysaccharide lyase 5 family.


ensembl_gene_id: H681_19465
symbol: AGI25760.1
gene_biotype: protein_coding
description:
  Alginate o-acetyltransferase AlgI; COG1696 Predicted membrane protein involved in D-alanine export; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: H681_19480
symbol: AGI25763.1
gene_biotype: protein_coding
description:
  Phosphomannose isomerase / guanosine 5'-diphospho-D-mannose pyrophosphorylase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: H681_19510
symbol: AGI25769.1
gene_biotype: protein_coding
description:
  Fusaric acid resistance protein; COG1566 Multidrug resistance efflux pump; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_19535
symbol: AGI25774.1
gene_biotype: protein_coding
description:
  Putative 2-hydroxyacid dehydrogenase; COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: H681_19540
symbol: AGI25775.1
gene_biotype: protein_coding
description:
  Chain length determinant protein; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.


ensembl_gene_id: H681_19585
symbol: AGI25784.1
gene_biotype: protein_coding
description:
  Putative dehydrogenase/reductase oxidoreductase protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_19670
symbol: AGI25801.1
gene_biotype: protein_coding
description:
  phytanoyl-CoA dioxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: H681_19720
symbol: AGI25811.1
gene_biotype: protein_coding
description:
  Thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: H681_19750
symbol: AGI25817.1
gene_biotype: protein_coding
description:
  Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: H681_19765
symbol: AGI25820.1
gene_biotype: protein_coding
description:
  BNR repeat-containing protein; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: H681_19800
symbol: AGI25827.1
gene_biotype: protein_coding
description:
  Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase.


ensembl_gene_id: H681_19830
symbol: AGI25833.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: H681_19915
symbol: AGI25850.1
gene_biotype: protein_coding
description:
  Putative epoxide hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_19955
symbol: AGI25858.1
gene_biotype: protein_coding
description:
  Dihydromonapterin reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: H681_19990
symbol: cysZ
gene_biotype: protein_coding
description:
  Sulfate transport protein CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: H681_20035
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: H681_20040
symbol: AGI25875.1
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: H681_20135
symbol: rsmC
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: H681_20250
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: H681_20270
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: H681_20355
symbol: AGI25938.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: H681_20365
symbol: AGI25940.1
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: H681_20370
symbol: AGI25941.1
gene_biotype: protein_coding
description:
  COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis.


ensembl_gene_id: H681_20395
symbol: AGI25946.1
gene_biotype: protein_coding
description:
  Phospholipase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: H681_20480
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: H681_20510
symbol: argP
gene_biotype: protein_coding
description:
  Chromosome replication initiation inhibitor protein; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: H681_20525
symbol: AGI25972.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: H681_20535
symbol: AGI25974.1
gene_biotype: protein_coding
description:
  Insulin-cleaving metalloproteinase outer membrane protein; COG3487 Uncharacterized iron-regulated protein.


ensembl_gene_id: H681_20555
symbol: AGI25978.1
gene_biotype: protein_coding
description:
  Putative Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: H681_20570
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: H681_20580
symbol: AGI25983.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P)+. May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers; Belongs to the bacterial renalase family.


ensembl_gene_id: H681_20615
symbol: AGI25990.1
gene_biotype: protein_coding
description:
  Lipid A 3-O-deacylase; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.


ensembl_gene_id: H681_20625
symbol: AGI25992.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein MoeB; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: H681_20630
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: H681_20635
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: H681_20640
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: H681_20650
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: H681_20655
symbol: ipk
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: H681_20660
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: H681_20665
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: H681_20675
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: H681_20755
symbol: vapC
gene_biotype: protein_coding
description:
  PilT domain-containing protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: H681_20770
symbol: AGI26021.1
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: H681_20775
symbol: AGI26022.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase.


ensembl_gene_id: H681_20785
symbol: AGI26024.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: H681_20845
symbol: msrQ
gene_biotype: protein_coding
description:
  Sulfite oxidase subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, u [...]


ensembl_gene_id: H681_20850
symbol: msrP
gene_biotype: protein_coding
description:
  TMAO/DMSO reductase; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) [...]


ensembl_gene_id: H681_20855
symbol: AGI26038.1
gene_biotype: protein_coding
description:
  COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: H681_20860
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: H681_20870
symbol: AGI26041.1
gene_biotype: protein_coding
description:
  Acetolactate synthase 3 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: H681_20890
symbol: AGI26045.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: H681_20905
symbol: AGI26048.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H681_20915
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin importer ATP-binding subunit; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_20920
symbol: AGI26051.1
gene_biotype: protein_coding
description:
  Hemin ABC transporter, permease protein PhuU; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: H681_20930
symbol: sfsA
gene_biotype: protein_coding
description:
  DNA-binding transcriptional regulator; COG1489 DNA-binding protein, stimulates sugar fermentation; Belongs to the SfsA family.


ensembl_gene_id: H681_20940
symbol: dksA-2
gene_biotype: protein_coding
description:
  TraR/DksA family transcriptional regulator; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: H681_20945
symbol: gluQ
gene_biotype: protein_coding
description:
  glutamyl-Q tRNA(Asp) ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: H681_20965
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: H681_20975
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: H681_20980
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: H681_20985
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: H681_21005
symbol: AGI26068.1
gene_biotype: protein_coding
description:
  Transcriptional regulator FimZ; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: H681_21040
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: H681_21045
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: H681_21050
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: H681_21055
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: H681_21060
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: H681_21065
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: H681_21070
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation protein RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: H681_21075
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: H681_21080
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: H681_21085
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: H681_21090
symbol: AGI26085.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: H681_21095
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: H681_21100
symbol: rrmJ
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: H681_21115
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: H681_21135
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: H681_21140
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: H681_21150
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]


ensembl_gene_id: H681_21180
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: H681_21195
symbol: lldD
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.


ensembl_gene_id: H681_21210
symbol: AGI26109.1
gene_biotype: protein_coding
description:
  Two-component regulator system signal sensor kinase PmrB; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: H681_21250
symbol: AGI26117.1
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATP-binding subunit; COG3839 ABC-type sugar transport systems, ATPase components.


ensembl_gene_id: H681_21280
symbol: AGI26123.1
gene_biotype: protein_coding
description:
  PilZ domain-containing protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: H681_21285
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: H681_21300
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: H681_21315
symbol: AGI26130.1
gene_biotype: protein_coding
description:
  Putative c4-dicarboxylate-binding protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.


ensembl_gene_id: H681_21325
symbol: AGI26132.1
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: H681_21345
symbol: AGI26136.1
gene_biotype: protein_coding
description:
  Oxidoreductase, small subunit; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: H681_21375
symbol: AGI26142.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen.


ensembl_gene_id: H681_21420
symbol: AGI26151.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein with EFhand domain; COG5126 Ca2+-binding protein (EF-Hand superfamily).


ensembl_gene_id: H681_21440
symbol: cmoM
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: H681_21470
symbol: ddpX-2
gene_biotype: protein_coding
description:
  Peptidase M15D, vanX D-ala-D-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.


ensembl_gene_id: H681_21510
symbol: AGI26169.1
gene_biotype: protein_coding
description:
  Addiction module antidote family protein; COG3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain.


ensembl_gene_id: H681_21525
symbol: selA
gene_biotype: protein_coding
description:
  Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: H681_21530
symbol: fdhE
gene_biotype: protein_coding
description:
  Formate dehydrogenase accessory protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: H681_21540
symbol: AGI26175.1
gene_biotype: protein_coding
description:
  Nitrate-inducible formate dehydrogenase subunit beta; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: H681_21545
symbol: AGI26176.1
gene_biotype: protein_coding
description:
  Formate dehydrogenase-O, major subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: H681_21550
symbol: AGI26177.1
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: H681_21570
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: H681_21590
symbol: AGI26185.1
gene_biotype: protein_coding
description:
  N-hydroxyarylamine O-acetyltransferase; COG2162 Arylamine N-acetyltransferase; Belongs to the arylamine N-acetyltransferase family.


ensembl_gene_id: H681_21595
symbol: AGI26186.1
gene_biotype: protein_coding
description:
  Cupin 2 conserved barrel domain protein; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: H681_21635
symbol: AGI26194.1
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase-activating protein; COG1180 Pyruvate-formate lyase-activating enzyme.


ensembl_gene_id: H681_21670
symbol: AGI26201.1
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: H681_21685
symbol: dipZ
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein precursor; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: H681_21690
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: H681_21695
symbol: AGI26206.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: H681_21700
symbol: AGI26207.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: H681_21705
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: H681_21715
symbol: dusB
gene_biotype: protein_coding
description:
  NifR3 family TIM-barrel protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: H681_21720
symbol: fis
gene_biotype: protein_coding
description:
  Global DNA-binding transcriptional dual regulator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: H681_21725
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: H681_21745
symbol: AGI26216.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: H681_21755
symbol: AGI26218.1
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: H681_21760
symbol: AGI26219.1
gene_biotype: protein_coding
description:
  Urea ABC transporter ATP-binding protein UrtD; COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: H681_21775
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: H681_21780
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: H681_21790
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: H681_21810
symbol: AGI26229.1
gene_biotype: protein_coding
description:
  Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase family. Oxaloacetate decarboxylase subfamily.


ensembl_gene_id: H681_21855
symbol: AGI26238.1
gene_biotype: protein_coding
description:
  Phosphinothricin N-acetyltransferase (antibiotic resistance) protein; COG1247 Sortase and related acyltransferases.


ensembl_gene_id: H681_21890
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: H681_21895
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: H681_21900
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: H681_21925
symbol: AGI26252.1
gene_biotype: protein_coding
description:
  Benzoylformate decarboxylase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: H681_21940
symbol: AGI26255.1
gene_biotype: protein_coding
description:
  Putative vanillate O-demethylase oxygenase subunit oxidoreductase protein; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: H681_21955
symbol: AGI26258.1
gene_biotype: protein_coding
description:
  COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: H681_21965
symbol: AGI26260.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: H681_21970
symbol: AGI26261.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: H681_21985
symbol: AGI26264.1
gene_biotype: protein_coding
description:
  Putative ABC transporter binding protein subunit; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: H681_21995
symbol: AGI26266.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: H681_22005
symbol: nadE
gene_biotype: protein_coding
description:
  NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: H681_22020
symbol: AGI26271.1
gene_biotype: protein_coding
description:
  Putative lysine decarboxylase; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: H681_22075
symbol: AGI26282.1
gene_biotype: protein_coding
description:
  Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: H681_22080
symbol: AGI26283.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: H681_22095
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: H681_22110
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: H681_22115
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: H681_22120
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: H681_22140
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: H681_22145
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: H681_22150
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: H681_22155
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: H681_22170
symbol: nnrE
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: H681_22175
symbol: queG
gene_biotype: protein_coding
description:
  Iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: H681_22180
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: H681_22185
symbol: rsgA
gene_biotype: protein_coding
description:
  GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: H681_22210
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: H681_22225
symbol: AGI26312.1
gene_biotype: protein_coding
description:
  Response regulator receiver modulated diguanylate cyclase/phosphodiesterase; COG2202 FOG: PAS/PAC domain.


ensembl_gene_id: H681_22250
symbol: AGI26317.1
gene_biotype: protein_coding
description:
  Glycosyltransferase; COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family.


ensembl_gene_id: H681_22260
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: H681_22275
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: H681_22285
symbol: cpdA
gene_biotype: protein_coding
description:
  Calcineurin phosphoesterase C-terminal domain-containing protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: H681_22295
symbol: nudF
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase NudF; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes.


ensembl_gene_id: H681_22305
symbol: AGI26328.1
gene_biotype: protein_coding
description:
  Permease for cytosine/purines,uracil,thiamine,allantoin family protein; COG1457 Purine-cytosine permease and related proteins.


ensembl_gene_id: H681_22310
symbol: thiC
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: H681_22325
symbol: AGI26332.1
gene_biotype: protein_coding
description:
  Putative extracellular solute-binding protein; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: H681_22345
symbol: AGI26336.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: H681_22390
symbol: hldE
gene_biotype: protein_coding
description:
  Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: H681_22405
symbol: msbA
gene_biotype: protein_coding
description:
  Transport protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: H681_22440
symbol: AGI26355.1
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase.


ensembl_gene_id: H681_22465
symbol: AGI26360.1
gene_biotype: protein_coding
description:
  Putative lipopolysaccharide biosynthesis-like protein; COG3642 Mn2+-dependent serine/threonine protein kinase.


ensembl_gene_id: H681_22475
symbol: AGI26362.1
gene_biotype: protein_coding
description:
  Lipopolysaccharide core heptose(I) kinase RfaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.


ensembl_gene_id: H681_22495
symbol: glnE
gene_biotype: protein_coding
description:
  Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]


ensembl_gene_id: H681_22505
symbol: AGI26368.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: H681_22515
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: H681_22530
symbol: nhaP2
gene_biotype: protein_coding
description:
  Potassium/proton antiporter; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.


ensembl_gene_id: H681_22540
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: H681_22585
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: H681_22605
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: H681_22610
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: H681_22615
symbol: AGI26390.1
gene_biotype: protein_coding
description:
  Type 4 fimbrial biogenesis outer membrane protein PilQ precursor; COG4796 Type II secretory pathway, component HofQ.


ensembl_gene_id: H681_22665
symbol: AGI26400.1
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: H681_22680
symbol: AGI26403.1
gene_biotype: protein_coding
description:
  D-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: H681_22685
symbol: AGI26404.1
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: H681_22695
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: H681_22700
symbol: ligB
gene_biotype: protein_coding
description:
  NAD-dependent DNA ligase LigB; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: H681_22750
symbol: AGI26417.1
gene_biotype: protein_coding
description:
  Taurine-transporting ATPase; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: H681_22755
symbol: AGI26418.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: H681_22790
symbol: AGI26425.1
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: H681_22795
symbol: rhlE
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: H681_22805
symbol: AGI26428.1
gene_biotype: protein_coding
description:
  Polar amino acid ABC transporter, inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: H681_22810
symbol: AGI26429.1
gene_biotype: protein_coding
description:
  Putative binding protein component of ABC transporter; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: H681_22820
symbol: opgG
gene_biotype: protein_coding
description:
  Glucan biosynthesis protein G; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: H681_22825
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: H681_22830
symbol: AGI26433.1
gene_biotype: protein_coding
description:
  Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: H681_22880
symbol: AGI26443.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4175 ABC-type proline/glycine betaine transport system, ATPase component.


ensembl_gene_id: H681_22890
symbol: AGI26445.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: H681_22895
symbol: AGI26446.1
gene_biotype: protein_coding
description:
  Permease, cytosine/purine, uracil, thiamine, allantoin family protein; COG1457 Purine-cytosine permease and related proteins; Belongs to the purine-cytosine permease (2.A.39) family.


ensembl_gene_id: H681_22920
symbol: AGI26451.1
gene_biotype: protein_coding
description:
  N-formimino-L-glutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: H681_22960
symbol: thiI
gene_biotype: protein_coding
description:
  tRNA s(4)U8 sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: H681_22990
symbol: ntrC
gene_biotype: protein_coding
description:
  Two-component response regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: H681_22995
symbol: trmL
gene_biotype: protein_coding
description:
  RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: H681_23005
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: H681_23010
symbol: AGI26469.1
gene_biotype: protein_coding
description:
  Dithiol-glutaredoxin protein; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: H681_23050
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: H681_23055
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase.


ensembl_gene_id: H681_23065
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: H681_23090
symbol: AGI26485.1
gene_biotype: protein_coding
description:
  Oxidative damage protection protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: H681_23165
symbol: AGI26500.1
gene_biotype: protein_coding
description:
  Periplasmic binding protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: H681_23225
symbol: AGI26512.1
gene_biotype: protein_coding
description:
  UDP-2-acetamido-2-deoxy-d-glucuronic acid 3-dehydrogenase, WbpB; COG0673 Predicted dehydrogenases and related proteins.


ensembl_gene_id: H681_23235
symbol: AGI26514.1
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: H681_23240
symbol: AGI26515.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: H681_23285
symbol: AGI26524.1
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: H681_23295
symbol: AGI26526.1
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: H681_23300
symbol: AGI26527.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: H681_23305
symbol: AGI26528.1
gene_biotype: protein_coding
description:
  Putative two-component sensor; COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system.


ensembl_gene_id: H681_23335
symbol: AGI26534.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: H681_23365
symbol: AGI26540.1
gene_biotype: protein_coding
description:
  Pilus biogenesis protein tapA precursor; COG4969 Tfp pilus assembly protein, major pilin PilA; Belongs to the N-Me-Phe pilin family.


ensembl_gene_id: H681_23400
symbol: AGI26547.1
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: H681_23435
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: H681_23440
symbol: hslO
gene_biotype: protein_coding
description:
  Hsp33-like chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: H681_23450
symbol: AGI26557.1
gene_biotype: protein_coding
description:
  Heat shock protein; COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); Belongs to the HSP15 family.


ensembl_gene_id: H681_23460
symbol: rimK
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the RimK family.


ensembl_gene_id: H681_23465
symbol: AGI26560.1
gene_biotype: protein_coding
description:
  LD-carboxypeptidase; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.


ensembl_gene_id: H681_23490
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: H681_23520
symbol: AGI26571.1
gene_biotype: protein_coding
description:
  Nodulation efficiency protein D (NfeD) family protein; COG1585 Membrane protein implicated in regulation of membrane protease activity.


ensembl_gene_id: H681_23525
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: H681_23545
symbol: AGI26576.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase PtsP; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: H681_23550
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: H681_23575
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: H681_23580
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: H681_23605
symbol: potA-3
gene_biotype: protein_coding
description:
  Putative ATP-binding component of ABC transporter; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_23610
symbol: AGI26589.1
gene_biotype: protein_coding
description:
  ABC transporter permease; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: H681_23655
symbol: AGI26598.1
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: H681_23710
symbol: AGI26609.1
gene_biotype: protein_coding
description:
  Polyamine transport protein PotI; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: H681_23715
symbol: AGI26610.1
gene_biotype: protein_coding
description:
  Polyamine transport protein PotH; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: H681_23720
symbol: potA-4
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_23735
symbol: AGI26614.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H681_23765
symbol: aguA
gene_biotype: protein_coding
description:
  Agmatine deiminase; Mediates the hydrolysis of agmatine into N- carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.


ensembl_gene_id: H681_23820
symbol: AGI26631.1
gene_biotype: protein_coding
description:
  Tyrosine-protein kinase; COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.


ensembl_gene_id: H681_23835
symbol: AGI26634.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: H681_23870
symbol: AGI26641.1
gene_biotype: protein_coding
description:
  Sulfate transport protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: H681_23880
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate transport protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: H681_23915
symbol: AGI26650.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H681_23960
symbol: cyaY
gene_biotype: protein_coding
description:
  Frataxin-like protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: H681_23980
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: H681_23990
symbol: xerC
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: H681_24080
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: H681_24085
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.


ensembl_gene_id: H681_24100
symbol: dadX
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: H681_24170
symbol: AGI26701.1
gene_biotype: protein_coding
description:
  Putative dipeptide ABC transporter binding protein subunit; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: H681_24180
symbol: AGI26703.1
gene_biotype: protein_coding
description:
  Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: H681_24185
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: H681_24195
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: H681_24210
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: H681_24225
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: H681_24240
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: H681_24245
symbol: AGI26716.1
gene_biotype: protein_coding
description:
  Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: H681_24280
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: H681_24295
symbol: AGI26726.1
gene_biotype: protein_coding
description:
  DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: H681_24300
symbol: AGI26727.1
gene_biotype: protein_coding
description:
  Putative rubredoxin reductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the FAD-dependent oxidoreductase family.


ensembl_gene_id: H681_24315
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: H681_24320
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: H681_24360
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: H681_24365
symbol: AGI26740.1
gene_biotype: protein_coding
description:
  Membrane protein component of ABC phosphate transporter; COG4985 ABC-type phosphate transport system, auxiliary component.


ensembl_gene_id: H681_24370
symbol: AGI26741.1
gene_biotype: protein_coding
description:
  Membrane protein component of ABC phosphate transporter; COG4590 ABC-type uncharacterized transport system, permease component.


ensembl_gene_id: H681_24390
symbol: betA
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: H681_24395
symbol: betB
gene_biotype: protein_coding
description:
  Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: H681_24455
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: H681_24460
symbol: purE
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: H681_24525
symbol: AGI26772.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD-binding subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: H681_24540
symbol: AGI26775.1
gene_biotype: protein_coding
description:
  Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: H681_24575
symbol: AGI26782.1
gene_biotype: protein_coding
description:
  Sarcosine oxidase subunit alpha; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.


ensembl_gene_id: H681_24590
symbol: AGI26785.1
gene_biotype: protein_coding
description:
  Glutathione-independent formaldehyde dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: H681_24615
symbol: AGI26790.1
gene_biotype: protein_coding
description:
  Putative acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: H681_24660
symbol: AGI26799.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism.


ensembl_gene_id: H681_24715
symbol: AGI26810.1
gene_biotype: protein_coding
description:
  Copper-containing nitrite reductase; COG2132 Putative multicopper oxidases; Belongs to the multicopper oxidase family.


ensembl_gene_id: H681_24725
symbol: AGI26812.1
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: H681_24730
symbol: AGI26813.1
gene_biotype: protein_coding
description:
  Regulator of cell morphogenesis and NO signaling; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: H681_24750
symbol: AGI26817.1
gene_biotype: protein_coding
description:
  COG3256 Nitric oxide reductase large subunit; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: H681_24785
symbol: nosZ
gene_biotype: protein_coding
description:
  Nitrous-oxide reductase; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide; In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.


ensembl_gene_id: H681_24850
symbol: AGI26837.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG0001 Glutamate-1-semialdehyde aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: H681_24870
symbol: AGI26841.1
gene_biotype: protein_coding
description:
  Potassium efflux transporter; COG4651 Kef-type K+ transport system, predicted NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: H681_24875
symbol: pdxY
gene_biotype: protein_coding
description:
  Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: H681_24920
symbol: AGI26851.1
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: H681_24960
symbol: AGI26859.1
gene_biotype: protein_coding
description:
  Class II aldolase/adducin domain protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: H681_25020
symbol: AGI26871.1
gene_biotype: protein_coding
description:
  Choline ABC transporter permease; COG4176 ABC-type proline/glycine betaine transport system, permease component.


ensembl_gene_id: H681_25115
symbol: lcdH
gene_biotype: protein_coding
description:
  3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.


ensembl_gene_id: H681_25125
symbol: AGI26892.1
gene_biotype: protein_coding
description:
  Glycine betaine/L-proline ABC transporter, periplasmic substrate-binding protein; COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components.


ensembl_gene_id: H681_25210
symbol: gltP
gene_biotype: protein_coding
description:
  Glutamate/aspartate:proton symporter; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.


ensembl_gene_id: H681_25265
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: H681_25270
symbol: atpC
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: H681_25275
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: H681_25280
symbol: atpG
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: H681_25285
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: H681_25290
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: H681_25295
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: H681_25300
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: H681_25305
symbol: atpB
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: H681_25315
symbol: AGI26930.1
gene_biotype: protein_coding
description:
  parB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: H681_25325
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: H681_25330
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: H681_25335
symbol: trmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: H681_25340
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: H681_25345
symbol: AGI26936.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: H681_25350
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


