# geneInfo

ensembl_gene_id: SPICUR_00005
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: SPICUR_00010
symbol: AGY91031.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...]


ensembl_gene_id: SPICUR_00015
symbol: recF
gene_biotype: protein_coding
description:
  Hypothetical protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: SPICUR_00020
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SPICUR_00025
symbol: AGY91034.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00040
symbol: glyQ
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00045
symbol: glnA
gene_biotype: protein_coding
description:
  Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00055
symbol: ntrC
gene_biotype: protein_coding
description:
  Hypothetical protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: SPICUR_00060
symbol: trmL
gene_biotype: protein_coding
description:
  Hypothetical protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: SPICUR_00065
symbol: gpsA
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SPICUR_00070
symbol: secB
gene_biotype: protein_coding
description:
  Hypothetical protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: SPICUR_00085
symbol: AGY91046.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the peptidase S41A family.


ensembl_gene_id: SPICUR_00090
symbol: ubiB
gene_biotype: protein_coding
description:
  Hypothetical protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: SPICUR_00100
symbol: ubiE
gene_biotype: protein_coding
description:
  Hypothetical protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: SPICUR_00110
symbol: hslU
gene_biotype: protein_coding
description:
  Hypothetical protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: SPICUR_00115
symbol: hslV
gene_biotype: protein_coding
description:
  Peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: SPICUR_00120
symbol: xerC
gene_biotype: protein_coding
description:
  Hypothetical protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: SPICUR_00130
symbol: dapF
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: SPICUR_00135
symbol: lysA
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: SPICUR_00160
symbol: hemC
gene_biotype: protein_coding
description:
  Hypothetical protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: SPICUR_00165
symbol: AGY91062.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: SPICUR_00185
symbol: AGY91066.1
gene_biotype: protein_coding
description:
  Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00220
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: SPICUR_00225
symbol: hemF
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: SPICUR_00235
symbol: moaA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: SPICUR_00240
symbol: tsaC
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: SPICUR_00245
symbol: topA
gene_biotype: protein_coding
description:
  Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]


ensembl_gene_id: SPICUR_00250
symbol: smg
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the Smg family.


ensembl_gene_id: SPICUR_00265
symbol: def
gene_biotype: protein_coding
description:
  Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: SPICUR_00270
symbol: fmt
gene_biotype: protein_coding
description:
  Hypothetical protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: SPICUR_00295
symbol: trkA
gene_biotype: protein_coding
description:
  Involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00300
symbol: AGY91089.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: SPICUR_00310
symbol: dtd
gene_biotype: protein_coding
description:
  Hypothetical protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: SPICUR_00320
symbol: hisH
gene_biotype: protein_coding
description:
  Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: SPICUR_00330
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: SPICUR_00345
symbol: tatA
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: SPICUR_00355
symbol: tatC
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: SPICUR_00365
symbol: AGY91102.1
gene_biotype: protein_coding
description:
  Hypothetical protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: SPICUR_00370
symbol: AGY91103.1
gene_biotype: protein_coding
description:
  E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00375
symbol: djlA
gene_biotype: protein_coding
description:
  Hypothetical protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: SPICUR_00385
symbol: AGY91106.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0312 family.


ensembl_gene_id: SPICUR_00425
symbol: AGY91114.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SPICUR_00430
symbol: AGY91115.1
gene_biotype: protein_coding
description:
  Isocitrate lyase; Catalyzes the reversible formation of glyoxylate and succinate from isocitrate; glyoxylate bypass pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00435
symbol: AGY91116.1
gene_biotype: protein_coding
description:
  NADPH-dependent FMN reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00445
symbol: AGY91118.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: SPICUR_00455
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: SPICUR_00460
symbol: dnaG
gene_biotype: protein_coding
description:
  Hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: SPICUR_00470
symbol: rpsU
gene_biotype: protein_coding
description:
  30S ribosomal protein S21; A small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: SPICUR_00475
symbol: tsaD
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: SPICUR_00480
symbol: plsY
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: SPICUR_00485
symbol: AGY91125.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: SPICUR_00505
symbol: uppP
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: SPICUR_00510
symbol: cca
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: SPICUR_00525
symbol: AGY91132.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: SPICUR_00530
symbol: AGY91133.1
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: SPICUR_00535
symbol: aroQ
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: SPICUR_00545
symbol: dsbD
gene_biotype: protein_coding
description:
  Hypothetical protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: SPICUR_00550
symbol: groS
gene_biotype: protein_coding
description:
  Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: SPICUR_00555
symbol: groEL
gene_biotype: protein_coding
description:
  Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: SPICUR_00560
symbol: glnE
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]


ensembl_gene_id: SPICUR_00565
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SPICUR_00585
symbol: hldD
gene_biotype: protein_coding
description:
  Nucleotide-sugar epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: SPICUR_00605
symbol: AGY91147.1
gene_biotype: protein_coding
description:
  NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00620
symbol: hldE
gene_biotype: protein_coding
description:
  Nucleotidyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: SPICUR_00625
symbol: kdkA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: SPICUR_00635
symbol: AGY91152.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: SPICUR_00665
symbol: rpmB
gene_biotype: protein_coding
description:
  50S ribosomal protein L28; Required for 70S ribosome assembly; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: SPICUR_00670
symbol: AGY91159.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: SPICUR_00695
symbol: AGY91164.1
gene_biotype: protein_coding
description:
  Cytochrome D ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00730
symbol: hemH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: SPICUR_00740
symbol: AGY91173.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0753 family.


ensembl_gene_id: SPICUR_00775
symbol: AGY91180.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the SOS response-associated peptidase family.


ensembl_gene_id: SPICUR_00795
symbol: AGY91184.1
gene_biotype: protein_coding
description:
  Cobalt transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_00810
symbol: AGY91187.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0178 family.


ensembl_gene_id: SPICUR_00845
symbol: AGY91194.1
gene_biotype: protein_coding
description:
  Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: SPICUR_00885
symbol: AGY91202.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: SPICUR_00905
symbol: AGY91206.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SPICUR_00950
symbol: AGY91214.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: SPICUR_00970
symbol: AGY91218.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SPICUR_00975
symbol: modC
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: SPICUR_00985
symbol: AGY91221.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the proline racemase family.


ensembl_gene_id: SPICUR_01005
symbol: AGY91225.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DapA family.


ensembl_gene_id: SPICUR_01015
symbol: AGY91227.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: SPICUR_01025
symbol: AGY91229.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SPICUR_01070
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: SPICUR_01085
symbol: AGY91239.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.


ensembl_gene_id: SPICUR_01100
symbol: AGY91242.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SPICUR_01125
symbol: AGY91247.1
gene_biotype: protein_coding
description:
  Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_01135
symbol: ppc
gene_biotype: protein_coding
description:
  Hypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: SPICUR_01140
symbol: pyrE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: SPICUR_01150
symbol: argB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: SPICUR_01165
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: SPICUR_01170
symbol: AGY91255.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: SPICUR_01175
symbol: AGY91256.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0758 family.


ensembl_gene_id: SPICUR_01180
symbol: rpoH
gene_biotype: protein_coding
description:
  Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: SPICUR_01185
symbol: AGY91258.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: SPICUR_01195
symbol: ftsY
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: SPICUR_01210
symbol: AGY91263.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: SPICUR_01215
symbol: coaD
gene_biotype: protein_coding
description:
  Hypothetical protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: SPICUR_01240
symbol: purE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: SPICUR_01245
symbol: purK
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: SPICUR_01275
symbol: AGY91275.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: SPICUR_01295
symbol: AGY91279.1
gene_biotype: protein_coding
description:
  Nitrogen regulatory protein P-II 1; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the P(II) protein family.


ensembl_gene_id: SPICUR_01300
symbol: AGY91280.1
gene_biotype: protein_coding
description:
  Ammonium transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_01320
symbol: priA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: SPICUR_01330
symbol: AGY91286.1
gene_biotype: protein_coding
description:
  Hypothetical protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: SPICUR_01335
symbol: AGY91287.1
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_01345
symbol: AGY90976.1
gene_biotype: protein_coding
description:
  Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_01420
symbol: aroE
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: SPICUR_01425
symbol: AGY91304.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ALAD family.


ensembl_gene_id: SPICUR_01430
symbol: AGY91305.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the Nudix hydrolase family.


ensembl_gene_id: SPICUR_01435
symbol: hemE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: SPICUR_01440
symbol: AGY91307.1
gene_biotype: protein_coding
description:
  Glutamate synthase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_01450
symbol: AGY91309.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: SPICUR_01455
symbol: aroB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: SPICUR_01460
symbol: aroK
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: SPICUR_01495
symbol: gltA
gene_biotype: protein_coding
description:
  Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the citrate synthase family.


ensembl_gene_id: SPICUR_01500
symbol: rpmE2
gene_biotype: protein_coding
description:
  50S ribosomal protein L31; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to [...]


ensembl_gene_id: SPICUR_01515
symbol: AGY91322.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: SPICUR_01520
symbol: AGY91323.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: SPICUR_01525
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: SPICUR_01535
symbol: rpoZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: SPICUR_01540
symbol: AGY91327.1
gene_biotype: protein_coding
description:
  Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: SPICUR_01550
symbol: recG
gene_biotype: protein_coding
description:
  Hypothetical protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: SPICUR_01555
symbol: ubiC
gene_biotype: protein_coding
description:
  Hypothetical protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: SPICUR_01560
symbol: ubiA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: SPICUR_01570
symbol: bioC
gene_biotype: protein_coding
description:
  Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: SPICUR_01580
symbol: AGY91335.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: SPICUR_01585
symbol: AGY91336.1
gene_biotype: protein_coding
description:
  Cytochrome oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: SPICUR_01620
symbol: cyoE
gene_biotype: protein_coding
description:
  Hypothetical protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: SPICUR_01625
symbol: lipA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: SPICUR_01660
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the IlvD/Edd family.


ensembl_gene_id: SPICUR_01685
symbol: metXS
gene_biotype: protein_coding
description:
  Hypothetical protein; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.


ensembl_gene_id: SPICUR_01700
symbol: AGY91359.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: SPICUR_01715
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: SPICUR_01725
symbol: AGY91364.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: SPICUR_01735
symbol: gshB
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: SPICUR_01745
symbol: AGY91368.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: SPICUR_01750
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: SPICUR_01755
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: SPICUR_01760
symbol: AGY91371.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the transketolase family.


ensembl_gene_id: SPICUR_01765
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SPICUR_01770
symbol: pgk
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: SPICUR_01775
symbol: AGY91374.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the pyruvate kinase family.


ensembl_gene_id: SPICUR_01780
symbol: purC
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the SAICAR synthetase family.


ensembl_gene_id: SPICUR_01785
symbol: AGY91376.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DNA photolyase family.


ensembl_gene_id: SPICUR_01820
symbol: AGY91383.1
gene_biotype: protein_coding
description:
  Hypothetical protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: SPICUR_01830
symbol: AGY91385.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: SPICUR_01835
symbol: AGY91386.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: SPICUR_01840
symbol: trpE
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.


ensembl_gene_id: SPICUR_01845
symbol: AGY91388.1
gene_biotype: protein_coding
description:
  Anthranilate synthase subunit II; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_01850
symbol: trpD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: SPICUR_01855
symbol: trpC
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TrpC family.


ensembl_gene_id: SPICUR_01870
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: SPICUR_01875
symbol: rpsI
gene_biotype: protein_coding
description:
  30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: SPICUR_01910
symbol: msrA
gene_biotype: protein_coding
description:
  Hypothetical protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: SPICUR_01985
symbol: AGY91413.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_01995
symbol: AGY91415.1
gene_biotype: protein_coding
description:
  C4-dicarboxylate ABC transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02005
symbol: AGY90979.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N-Me-Phe pilin family.


ensembl_gene_id: SPICUR_02010
symbol: sucC
gene_biotype: protein_coding
description:
  malate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: SPICUR_02015
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: SPICUR_02020
symbol: nadE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: SPICUR_02025
symbol: AGY91420.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the P(II) protein family.


ensembl_gene_id: SPICUR_02030
symbol: bamD
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: SPICUR_02035
symbol: AGY91422.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: SPICUR_02040
symbol: AGY91423.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: SPICUR_02045
symbol: clpB
gene_biotype: protein_coding
description:
  Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: SPICUR_02055
symbol: AGY91426.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SPICUR_02075
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: SPICUR_02090
symbol: AGY91433.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the Dps family.


ensembl_gene_id: SPICUR_02100
symbol: AGY91435.1
gene_biotype: protein_coding
description:
  O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02140
symbol: AGY91443.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the amidase family.


ensembl_gene_id: SPICUR_02170
symbol: phnC
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: SPICUR_02180
symbol: cpoB
gene_biotype: protein_coding
description:
  Hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: SPICUR_02185
symbol: pal
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: SPICUR_02210
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: SPICUR_02215
symbol: ruvA
gene_biotype: protein_coding
description:
  Hypothetical protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: SPICUR_02220
symbol: ruvC
gene_biotype: protein_coding
description:
  Hypothetical protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: SPICUR_02235
symbol: AGY91461.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: SPICUR_02250
symbol: rbsK
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: SPICUR_02290
symbol: dapA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: SPICUR_02300
symbol: purL
gene_biotype: protein_coding
description:
  Hypothetical protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: SPICUR_02335
symbol: AGY91481.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02375
symbol: AGY91489.1
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: SPICUR_02400
symbol: metH
gene_biotype: protein_coding
description:
  B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: SPICUR_02415
symbol: purU
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: SPICUR_02420
symbol: AGY91498.1
gene_biotype: protein_coding
description:
  Heme ABC transporter ATP-binding protein; ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02425
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: SPICUR_02430
symbol: nrdR
gene_biotype: protein_coding
description:
  NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: SPICUR_02435
symbol: AGY91500.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: SPICUR_02445
symbol: ribB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: SPICUR_02450
symbol: ribH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: SPICUR_02455
symbol: AGY91504.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: SPICUR_02460
symbol: thiL
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: SPICUR_02475
symbol: AGY91508.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SPICUR_02485
symbol: AGY91510.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SPICUR_02490
symbol: AGY91511.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SPICUR_02495
symbol: AGY91512.1
gene_biotype: protein_coding
description:
  Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02520
symbol: rhlB
gene_biotype: protein_coding
description:
  Hypothetical protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: SPICUR_02525
symbol: AGY91518.1
gene_biotype: protein_coding
description:
  Glutaredoxin; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: SPICUR_02530
symbol: rnt
gene_biotype: protein_coding
description:
  Hypothetical protein; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: SPICUR_02535
symbol: pyrC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.


ensembl_gene_id: SPICUR_02540
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: SPICUR_02545
symbol: AGY91522.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: SPICUR_02565
symbol: nth
gene_biotype: protein_coding
description:
  Hypothetical protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: SPICUR_02570
symbol: AGY91527.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: SPICUR_02575
symbol: metG
gene_biotype: protein_coding
description:
  Hypothetical protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: SPICUR_02585
symbol: AGY91530.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: SPICUR_02600
symbol: purN
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: SPICUR_02605
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_02615
symbol: AGY91534.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DnaA family. HdA subfamily.


ensembl_gene_id: SPICUR_02625
symbol: AGY91536.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the WrbA family.


ensembl_gene_id: SPICUR_02650
symbol: proS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]


ensembl_gene_id: SPICUR_02655
symbol: AGY91542.1
gene_biotype: protein_coding
description:
  Acetolactate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02660
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: SPICUR_02665
symbol: AGY91544.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SPICUR_02670
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: SPICUR_02695
symbol: AGY91550.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SPICUR_02705
symbol: valS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: SPICUR_02735
symbol: pcnB
gene_biotype: protein_coding
description:
  Hypothetical protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: SPICUR_02745
symbol: panB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: SPICUR_02750
symbol: panC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: SPICUR_02755
symbol: pgi
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GPI family.


ensembl_gene_id: SPICUR_02760
symbol: queG
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: SPICUR_02765
symbol: nnrD
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]


ensembl_gene_id: SPICUR_02775
symbol: AGY90983.1
gene_biotype: protein_coding
description:
  Cell wall hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_02780
symbol: mutL
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: SPICUR_02785
symbol: miaA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: SPICUR_02790
symbol: AGY91567.1
gene_biotype: protein_coding
description:
  Hypothetical protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: SPICUR_02795
symbol: hflX
gene_biotype: protein_coding
description:
  Hypothetical protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: SPICUR_02815
symbol: hisZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: SPICUR_02820
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: SPICUR_02830
symbol: rnr
gene_biotype: protein_coding
description:
  Hypothetical protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: SPICUR_02845
symbol: priB
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: SPICUR_02850
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: SPICUR_02865
symbol: AGY90984.1
gene_biotype: protein_coding
description:
  DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: SPICUR_02870
symbol: AGY91581.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: SPICUR_02875
symbol: radA
gene_biotype: protein_coding
description:
  Hypothetical protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: SPICUR_02880
symbol: folD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: SPICUR_02890
symbol: AGY91584.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DEAD box helicase family.


ensembl_gene_id: SPICUR_02935
symbol: tig
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: SPICUR_02940
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SPICUR_02945
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: SPICUR_02950
symbol: lon
gene_biotype: protein_coding
description:
  Peptidase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: SPICUR_02955
symbol: AGY90985.1
gene_biotype: protein_coding
description:
  Transcriptional regulator; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: SPICUR_02975
symbol: AGY91594.1
gene_biotype: protein_coding
description:
  enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02985
symbol: AGY91596.1
gene_biotype: protein_coding
description:
  Microcin C ABC transporter permease YejB; With YejAEF is involved in resistance to microcin C; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02990
symbol: AGY91597.1
gene_biotype: protein_coding
description:
  ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_02995
symbol: AGY91598.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ABC transporter superfamily.


ensembl_gene_id: SPICUR_03000
symbol: der
gene_biotype: protein_coding
description:
  Hypothetical protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: SPICUR_03025
symbol: queA
gene_biotype: protein_coding
description:
  Hypothetical protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: SPICUR_03030
symbol: tgt
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...]


ensembl_gene_id: SPICUR_03035
symbol: yajC
gene_biotype: protein_coding
description:
  Hypothetical protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: SPICUR_03040
symbol: secD
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: SPICUR_03055
symbol: AGY91607.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: SPICUR_03060
symbol: trmJ
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: SPICUR_03080
symbol: AGY91612.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the HesB/IscA family.


ensembl_gene_id: SPICUR_03085
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: SPICUR_03090
symbol: rlmN
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: SPICUR_03120
symbol: adk
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: SPICUR_03130
symbol: pdxH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: SPICUR_03145
symbol: AGY91625.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: SPICUR_03150
symbol: AGY91626.1
gene_biotype: protein_coding
description:
  Membrane protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_03160
symbol: carA
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CarA family.


ensembl_gene_id: SPICUR_03165
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_03170
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: SPICUR_03180
symbol: rlmE
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: SPICUR_03185
symbol: hflB
gene_biotype: protein_coding
description:
  ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: SPICUR_03190
symbol: AGY91634.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: SPICUR_03195
symbol: glmM
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: SPICUR_03200
symbol: tpiA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: SPICUR_03205
symbol: AGY91637.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: SPICUR_03215
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: SPICUR_03220
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SPICUR_03225
symbol: nuoC
gene_biotype: protein_coding
description:
  Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: SPICUR_03230
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: SPICUR_03240
symbol: AGY91643.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: SPICUR_03245
symbol: AGY91644.1
gene_biotype: protein_coding
description:
  Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: SPICUR_03250
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: SPICUR_03255
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SPICUR_03260
symbol: AGY91647.1
gene_biotype: protein_coding
description:
  Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SPICUR_03265
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: SPICUR_03280
symbol: nuoN
gene_biotype: protein_coding
description:
  Hypothetical protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: SPICUR_03295
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: SPICUR_03305
symbol: infB
gene_biotype: protein_coding
description:
  Hypothetical protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: SPICUR_03310
symbol: rbfA
gene_biotype: protein_coding
description:
  Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: SPICUR_03315
symbol: truB
gene_biotype: protein_coding
description:
  Hypothetical protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: SPICUR_03320
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: SPICUR_03325
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: SPICUR_03345
symbol: AGY91662.1
gene_biotype: protein_coding
description:
  Sodium:solute symporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SPICUR_03355
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SPICUR_03360
symbol: gluQ
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: SPICUR_03375
symbol: AGY91668.1
gene_biotype: protein_coding
description:
  Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_03385
symbol: smc
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: SPICUR_03390
symbol: zipA
gene_biotype: protein_coding
description:
  Hypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: SPICUR_03395
symbol: ligA
gene_biotype: protein_coding
description:
  Hypothetical protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: SPICUR_03405
symbol: AGY91674.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the BolA/IbaG family.


ensembl_gene_id: SPICUR_03415
symbol: AGY91676.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the SUA5 family.


ensembl_gene_id: SPICUR_03420
symbol: AGY91677.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: SPICUR_03425
symbol: AGY91678.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SPICUR_03430
symbol: AGY91679.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SPICUR_03435
symbol: AGY91680.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: SPICUR_03465
symbol: ubiG
gene_biotype: protein_coding
description:
  Hypothetical protein; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: SPICUR_03470
symbol: AGY91687.1
gene_biotype: protein_coding
description:
  Hypothetical protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: SPICUR_03475
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SPICUR_03480
symbol: serC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: SPICUR_03500
symbol: aroA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: SPICUR_03510
symbol: AGY91695.1
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: SPICUR_03515
symbol: ihfB
gene_biotype: protein_coding
description:
  Transcriptional regulator; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: SPICUR_03525
symbol: lapB
gene_biotype: protein_coding
description:
  Hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: SPICUR_03530
symbol: pyrF
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: SPICUR_03580
symbol: AGY91708.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: SPICUR_03585
symbol: AGY91709.1
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: SPICUR_03620
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: SPICUR_03630
symbol: nadA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: SPICUR_03640
symbol: AGY91719.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the NadC/ModD family.


ensembl_gene_id: SPICUR_03645
symbol: dld
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: SPICUR_03690
symbol: AGY91729.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SPICUR_03755
symbol: AGY91742.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the alkaline phosphatase family.


ensembl_gene_id: SPICUR_03790
symbol: thrS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: SPICUR_03795
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: SPICUR_03800
symbol: rpmI
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: SPICUR_03805
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: SPICUR_03810
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: SPICUR_03815
symbol: pheT
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: SPICUR_03820
symbol: ihfA
gene_biotype: protein_coding
description:
  DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: SPICUR_03825
symbol: AGY91754.1
gene_biotype: protein_coding
description:
  MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_03835
symbol: AGY91755.1
gene_biotype: protein_coding
description:
  Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_03865
symbol: AGY91761.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial glucokinase family.


ensembl_gene_id: SPICUR_03875
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose 6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: SPICUR_03880
symbol: edd
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: SPICUR_03895
symbol: AGY91766.1
gene_biotype: protein_coding
description:
  Cysteine desulfurase activator complex subunit SufB; With SufCD activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_03910
symbol: AGY91769.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SPICUR_03930
symbol: AGY91773.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial secretin family.


ensembl_gene_id: SPICUR_03990
symbol: gshA
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: SPICUR_04035
symbol: AGY91794.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CinA family.


ensembl_gene_id: SPICUR_04040
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: SPICUR_04050
symbol: alaS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: SPICUR_04055
symbol: AGY91797.1
gene_biotype: protein_coding
description:
  Aspartokinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartokinase family.


ensembl_gene_id: SPICUR_04060
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: SPICUR_04095
symbol: AGY90991.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_04155
symbol: aceK
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: SPICUR_04230
symbol: AGY91829.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SPICUR_04235
symbol: AGY91830.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SPICUR_04260
symbol: AGY91835.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: SPICUR_04275
symbol: AGY91838.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: SPICUR_04305
symbol: AGY91844.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: SPICUR_04310
symbol: fumC
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: SPICUR_04320
symbol: uvrC
gene_biotype: protein_coding
description:
  Hypothetical protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: SPICUR_04340
symbol: AGY91849.1
gene_biotype: protein_coding
description:
  Dihydromonapterin reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_04375
symbol: AGY91855.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: SPICUR_04395
symbol: AGY91859.1
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SPICUR_04415
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: SPICUR_04420
symbol: AGY91863.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: SPICUR_04450
symbol: prpD
gene_biotype: protein_coding
description:
  2-methylcitrate dehydratase; Functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_04455
symbol: AGY91870.1
gene_biotype: protein_coding
description:
  Catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_04460
symbol: prpB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: SPICUR_04470
symbol: AGY91873.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SPICUR_04475
symbol: fabA
gene_biotype: protein_coding
description:
  Hypothetical protein; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: SPICUR_04480
symbol: dxs
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: SPICUR_04485
symbol: AGY91876.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0260 family.


ensembl_gene_id: SPICUR_04490
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: SPICUR_04495
symbol: AGY91878.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the peptidase S1C family.


ensembl_gene_id: SPICUR_04550
symbol: AGY91889.1
gene_biotype: protein_coding
description:
  Arsenic transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_04570
symbol: tmk
gene_biotype: protein_coding
description:
  Hypothetical protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: SPICUR_04575
symbol: mltG
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: SPICUR_04595
symbol: AGY91898.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SPICUR_04605
symbol: fabH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SPICUR_04610
symbol: plsX
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: SPICUR_04615
symbol: rpmF
gene_biotype: protein_coding
description:
  Some L32 proteins have zinc finger motifs consisting of CXXC while others do not; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: SPICUR_04625
symbol: AGY91904.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: SPICUR_04640
symbol: rne
gene_biotype: protein_coding
description:
  Hypothetical protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: SPICUR_04650
symbol: kdsB
gene_biotype: protein_coding
description:
  Hypothetical protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: SPICUR_04655
symbol: lpxK
gene_biotype: protein_coding
description:
  Hypothetical protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: SPICUR_04660
symbol: msbA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: SPICUR_04680
symbol: lolD
gene_biotype: protein_coding
description:
  ABC transporter; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: SPICUR_04690
symbol: sfsA
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the SfsA family.


ensembl_gene_id: SPICUR_04695
symbol: mfd
gene_biotype: protein_coding
description:
  Hypothetical protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: SPICUR_04710
symbol: nagZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: SPICUR_04720
symbol: gpmA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: SPICUR_04725
symbol: moaC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: SPICUR_04740
symbol: AGY91926.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GST superfamily.


ensembl_gene_id: SPICUR_04745
symbol: ispG
gene_biotype: protein_coding
description:
  Hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: SPICUR_04750
symbol: AGY91928.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: SPICUR_04775
symbol: dusA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: SPICUR_04810
symbol: pyrD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: SPICUR_04845
symbol: AGY91946.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: SPICUR_04850
symbol: AGY91947.1
gene_biotype: protein_coding
description:
  Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_04875
symbol: pcm
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: SPICUR_04880
symbol: surE
gene_biotype: protein_coding
description:
  Hypothetical protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: SPICUR_04890
symbol: truD
gene_biotype: protein_coding
description:
  Hypothetical protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: SPICUR_04895
symbol: ispF
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: SPICUR_04900
symbol: ispD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: SPICUR_04905
symbol: ftsB
gene_biotype: protein_coding
description:
  Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: SPICUR_04910
symbol: eno
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: SPICUR_04915
symbol: kdsA
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the KdsA family.


ensembl_gene_id: SPICUR_04920
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: SPICUR_04925
symbol: tilS
gene_biotype: protein_coding
description:
  Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: SPICUR_04930
symbol: accA
gene_biotype: protein_coding
description:
  Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: SPICUR_04945
symbol: lpxB
gene_biotype: protein_coding
description:
  Hypothetical protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: SPICUR_04950
symbol: lpxA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: SPICUR_04960
symbol: lpxD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: SPICUR_04965
symbol: AGY91970.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the skp family.


ensembl_gene_id: SPICUR_04980
symbol: dxr
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: SPICUR_04985
symbol: AGY91974.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CDS family.


ensembl_gene_id: SPICUR_04990
symbol: uppS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: SPICUR_04995
symbol: frr
gene_biotype: protein_coding
description:
  Hypothetical protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: SPICUR_05005
symbol: tsf
gene_biotype: protein_coding
description:
  Hypothetical protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: SPICUR_05010
symbol: rpsB
gene_biotype: protein_coding
description:
  30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: SPICUR_05015
symbol: map
gene_biotype: protein_coding
description:
  Hypothetical protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: SPICUR_05020
symbol: glnD
gene_biotype: protein_coding
description:
  Hypothetical protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: SPICUR_05030
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: SPICUR_05035
symbol: dapE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: SPICUR_05045
symbol: dapB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: SPICUR_05050
symbol: dnaJ
gene_biotype: protein_coding
description:
  Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]


ensembl_gene_id: SPICUR_05060
symbol: grpE
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]


ensembl_gene_id: SPICUR_05065
symbol: hrcA
gene_biotype: protein_coding
description:
  Hypothetical protein; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: SPICUR_05070
symbol: nadK
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: SPICUR_05080
symbol: fur
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the Fur family.


ensembl_gene_id: SPICUR_05090
symbol: AGY91994.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0125 (RnfH) family.


ensembl_gene_id: SPICUR_05100
symbol: smpB
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: SPICUR_05125
symbol: hisD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: SPICUR_05135
symbol: tauB
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: SPICUR_05150
symbol: AGY92006.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: SPICUR_05155
symbol: AGY92007.1
gene_biotype: protein_coding
description:
  Cytochrome C biogenesis protein CcmE; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_05195
symbol: AGY92015.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the hyi family.


ensembl_gene_id: SPICUR_05250
symbol: AGY92025.1
gene_biotype: protein_coding
description:
  Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_05310
symbol: AGY92037.1
gene_biotype: protein_coding
description:
  2-keto-gluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_05350
symbol: cysG
gene_biotype: protein_coding
description:
  Hypothetical protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: SPICUR_05360
symbol: AGY92047.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: SPICUR_05370
symbol: cynS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: SPICUR_05375
symbol: AGY92050.1
gene_biotype: protein_coding
description:
  Formate transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_05390
symbol: AGY92053.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal. Belongs to the Brp/Blh beta-carotene diooxygenase family.


ensembl_gene_id: SPICUR_05455
symbol: AGY92065.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.


ensembl_gene_id: SPICUR_05485
symbol: AGY92071.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FAD-dependent oxidoreductase family.


ensembl_gene_id: SPICUR_05535
symbol: AGY92081.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the peptidase S24 family.


ensembl_gene_id: SPICUR_05560
symbol: AGY92086.1
gene_biotype: protein_coding
description:
  tRNA-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_05570
symbol: AGY92088.1
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_05655
symbol: ade
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: SPICUR_05675
symbol: AGY92108.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: SPICUR_05700
symbol: panD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: SPICUR_05775
symbol: AGY92128.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: SPICUR_05835
symbol: recC
gene_biotype: protein_coding
description:
  Hypothetical protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme [...]


ensembl_gene_id: SPICUR_05905
symbol: AGY92154.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: SPICUR_05965
symbol: AGY90998.1
gene_biotype: protein_coding
description:
  ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_05985
symbol: AGY92169.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: SPICUR_05990
symbol: AGY92170.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: SPICUR_06000
symbol: orn
gene_biotype: protein_coding
description:
  Hypothetical protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: SPICUR_06005
symbol: rsgA
gene_biotype: protein_coding
description:
  Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: SPICUR_06025
symbol: AGY92177.1
gene_biotype: protein_coding
description:
  Glycine/betaine ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_06035
symbol: katG
gene_biotype: protein_coding
description:
  Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: SPICUR_06140
symbol: AGY92196.1
gene_biotype: protein_coding
description:
  Zn-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_06145
symbol: tadA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: SPICUR_06160
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: SPICUR_06165
symbol: xseA
gene_biotype: protein_coding
description:
  Hypothetical protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: SPICUR_06175
symbol: acpS
gene_biotype: protein_coding
description:
  Hypothetical protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: SPICUR_06180
symbol: pdxJ
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: SPICUR_06190
symbol: era
gene_biotype: protein_coding
description:
  Hypothetical protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: SPICUR_06195
symbol: rnc
gene_biotype: protein_coding
description:
  Hypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: SPICUR_06200
symbol: AGY92208.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the peptidase S26 family.


ensembl_gene_id: SPICUR_06205
symbol: lepA
gene_biotype: protein_coding
description:
  Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: SPICUR_06225
symbol: AGY92213.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor AlgU; Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: SPICUR_06240
symbol: sdhB
gene_biotype: protein_coding
description:
  Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur pr [...]


ensembl_gene_id: SPICUR_06245
symbol: AGY92217.1
gene_biotype: protein_coding
description:
  Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: SPICUR_06265
symbol: AGY92221.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GcvT family.


ensembl_gene_id: SPICUR_06280
symbol: lysS
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: SPICUR_06285
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: SPICUR_06305
symbol: AGY92229.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the BI1 family.


ensembl_gene_id: SPICUR_06325
symbol: AGY92233.1
gene_biotype: protein_coding
description:
  BCCT transporter; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: SPICUR_06335
symbol: recR
gene_biotype: protein_coding
description:
  Hypothetical protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: SPICUR_06340
symbol: AGY92236.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: SPICUR_06345
symbol: dnaX
gene_biotype: protein_coding
description:
  Hypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: SPICUR_06370
symbol: lon-2
gene_biotype: protein_coding
description:
  Hypothetical protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: SPICUR_06375
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: SPICUR_06395
symbol: gltX
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: SPICUR_06420
symbol: AGY92249.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: SPICUR_06465
symbol: AGY92258.1
gene_biotype: protein_coding
description:
  Copper-transporting P-type ATPase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_06470
symbol: mutS
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: SPICUR_06475
symbol: AGY92260.1
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: SPICUR_06505
symbol: hisC
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: SPICUR_06515
symbol: AGY92268.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: SPICUR_06525
symbol: serS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: SPICUR_06530
symbol: crcB
gene_biotype: protein_coding
description:
  Hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: SPICUR_06540
symbol: lolA
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: SPICUR_06555
symbol: aat
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: SPICUR_06560
symbol: bpt
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: SPICUR_06565
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: SPICUR_06570
symbol: clpA
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding protein; ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ClpA/ClpB family.


ensembl_gene_id: SPICUR_06575
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: SPICUR_06580
symbol: mnmA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: SPICUR_06595
symbol: tpx
gene_biotype: protein_coding
description:
  Hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: SPICUR_06630
symbol: glcB
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: SPICUR_06640
symbol: ppk
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: SPICUR_06645
symbol: AGY92294.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GppA/Ppx family.


ensembl_gene_id: SPICUR_06680
symbol: AGY92301.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SPICUR_06700
symbol: lexA
gene_biotype: protein_coding
description:
  LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: SPICUR_06720
symbol: dnaE2
gene_biotype: protein_coding
description:
  Hypothetical protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: SPICUR_06735
symbol: tmcA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: SPICUR_06740
symbol: AGY92312.1
gene_biotype: protein_coding
description:
  Hypothetical protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: SPICUR_06745
symbol: AGY92313.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the HSP15 family.


ensembl_gene_id: SPICUR_06755
symbol: AGY92315.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: SPICUR_06810
symbol: ribA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: SPICUR_06830
symbol: AGY92330.1
gene_biotype: protein_coding
description:
  Hypothetical protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.


ensembl_gene_id: SPICUR_06910
symbol: ectA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.


ensembl_gene_id: SPICUR_06915
symbol: ectC
gene_biotype: protein_coding
description:
  Ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.


ensembl_gene_id: SPICUR_06925
symbol: dsbB
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: SPICUR_06930
symbol: selO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: SPICUR_06955
symbol: AGY92355.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria; Belongs to the high-potential iron-sulfur protein (HiPIP) family.


ensembl_gene_id: SPICUR_06960
symbol: AGY92356.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: SPICUR_06990
symbol: AGY91001.1
gene_biotype: protein_coding
description:
  Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: SPICUR_07055
symbol: dnaQ
gene_biotype: protein_coding
description:
  Hypothetical protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: SPICUR_07070
symbol: gloB
gene_biotype: protein_coding
description:
  Hypothetical protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: SPICUR_07080
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: SPICUR_07085
symbol: AGY92380.1
gene_biotype: protein_coding
description:
  ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_07090
symbol: minC
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: SPICUR_07105
symbol: msrB
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: SPICUR_07115
symbol: rplS
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: SPICUR_07120
symbol: trmD
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: SPICUR_07125
symbol: rimM
gene_biotype: protein_coding
description:
  Hypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: SPICUR_07130
symbol: rpsP
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: SPICUR_07135
symbol: ffh
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to  [...]


ensembl_gene_id: SPICUR_07155
symbol: gltX-2
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: SPICUR_07160
symbol: lpxH
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: SPICUR_07185
symbol: metZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: SPICUR_07190
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: SPICUR_07205
symbol: AGY92404.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: SPICUR_07210
symbol: accD
gene_biotype: protein_coding
description:
  Hypothetical protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: SPICUR_07215
symbol: trpA
gene_biotype: protein_coding
description:
  Hypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: SPICUR_07220
symbol: trpB-2
gene_biotype: protein_coding
description:
  Hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: SPICUR_07225
symbol: trpF
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TrpF family.


ensembl_gene_id: SPICUR_07230
symbol: truA
gene_biotype: protein_coding
description:
  Hypothetical protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: SPICUR_07240
symbol: asd
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: SPICUR_07245
symbol: leuB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: SPICUR_07250
symbol: leuD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: SPICUR_07255
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: SPICUR_07265
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: SPICUR_07270
symbol: AGY92417.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the protein N5-glutamine methyltransferase family.


ensembl_gene_id: SPICUR_07280
symbol: psd
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: SPICUR_07290
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: SPICUR_07300
symbol: parC
gene_biotype: protein_coding
description:
  Hypothetical protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: SPICUR_07305
symbol: parE
gene_biotype: protein_coding
description:
  Hypothetical protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: SPICUR_07315
symbol: AGY92426.1
gene_biotype: protein_coding
description:
  GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_07330
symbol: srkA
gene_biotype: protein_coding
description:
  Hypothetical protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: SPICUR_07340
symbol: argD
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: SPICUR_07345
symbol: AGY92432.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: SPICUR_07355
symbol: pstB
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: SPICUR_07365
symbol: AGY92436.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SPICUR_07445
symbol: AGY91002.1
gene_biotype: protein_coding
description:
  Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_07465
symbol: AGY92455.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: SPICUR_07480
symbol: AGY92458.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 'phage' integrase family.


ensembl_gene_id: SPICUR_07500
symbol: ispH
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: SPICUR_07505
symbol: lspA
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: SPICUR_07510
symbol: ileS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: SPICUR_07515
symbol: AGY92464.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ribF family.


ensembl_gene_id: SPICUR_07520
symbol: murJ
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: SPICUR_07530
symbol: proB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: SPICUR_07535
symbol: obg
gene_biotype: protein_coding
description:
  Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: SPICUR_07540
symbol: rpmA
gene_biotype: protein_coding
description:
  50S ribosomal protein L27; Involved in the peptidyltransferase reaction during translation; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: SPICUR_07545
symbol: rplU
gene_biotype: protein_coding
description:
  Hypothetical protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: SPICUR_07570
symbol: coaE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: SPICUR_07575
symbol: zapD
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: SPICUR_07585
symbol: argJ
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: SPICUR_07590
symbol: secA
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: SPICUR_07600
symbol: lpxC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: SPICUR_07605
symbol: ftsZ
gene_biotype: protein_coding
description:
  Peptidase M23; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: SPICUR_07610
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: SPICUR_07615
symbol: ftsQ
gene_biotype: protein_coding
description:
  Hypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: SPICUR_07635
symbol: murG
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: SPICUR_07640
symbol: ftsW
gene_biotype: protein_coding
description:
  Hypothetical protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: SPICUR_07645
symbol: murD
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: SPICUR_07650
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: SPICUR_07655
symbol: murF
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: SPICUR_07660
symbol: murE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: SPICUR_07665
symbol: ftsI
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.


ensembl_gene_id: SPICUR_07675
symbol: rsmH
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: SPICUR_07680
symbol: mraZ
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the MraZ family.


ensembl_gene_id: SPICUR_07685
symbol: rsmI
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: SPICUR_07695
symbol: AGY92499.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0102 family.


ensembl_gene_id: SPICUR_07700
symbol: gmhA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: SPICUR_07720
symbol: AGY92504.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: SPICUR_07740
symbol: hisG
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: SPICUR_07745
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: SPICUR_07800
symbol: AGY92520.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SPICUR_07845
symbol: ychF
gene_biotype: protein_coding
description:
  Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: SPICUR_07850
symbol: pth
gene_biotype: protein_coding
description:
  Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: SPICUR_07855
symbol: rplY
gene_biotype: protein_coding
description:
  Hypothetical protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: SPICUR_07870
symbol: ispE
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: SPICUR_07875
symbol: AGY92532.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: SPICUR_07885
symbol: hemA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: SPICUR_07890
symbol: prfA
gene_biotype: protein_coding
description:
  Hypothetical protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: SPICUR_07895
symbol: dksA
gene_biotype: protein_coding
description:
  Molecular chaperone DnaK; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: SPICUR_07900
symbol: AGY92537.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: SPICUR_07910
symbol: prmC
gene_biotype: protein_coding
description:
  Hypothetical protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: SPICUR_07920
symbol: AGY92541.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: SPICUR_07925
symbol: gatB
gene_biotype: protein_coding
description:
  glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: SPICUR_07930
symbol: gatA
gene_biotype: protein_coding
description:
  Hypothetical protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: SPICUR_07935
symbol: gatC
gene_biotype: protein_coding
description:
  Hypothetical protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: SPICUR_07940
symbol: AGY92545.1
gene_biotype: protein_coding
description:
  Rod shape-determining protein Mbl; Functions in MreBCD complex in some organisms; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_07950
symbol: AGY92547.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: SPICUR_07955
symbol: mrdA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: SPICUR_07960
symbol: mrdB
gene_biotype: protein_coding
description:
  Hypothetical protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: SPICUR_07970
symbol: rlpA
gene_biotype: protein_coding
description:
  Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: SPICUR_07975
symbol: AGY92551.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the peptidase S11 family.


ensembl_gene_id: SPICUR_07980
symbol: AGY92552.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0250 family.


ensembl_gene_id: SPICUR_07985
symbol: lipB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: SPICUR_08000
symbol: lptD
gene_biotype: protein_coding
description:
  Hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: SPICUR_08005
symbol: surA
gene_biotype: protein_coding
description:
  Hypothetical protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: SPICUR_08010
symbol: pdxA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: SPICUR_08015
symbol: rsmA
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: SPICUR_08020
symbol: AGY92560.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: SPICUR_08040
symbol: AGY92564.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: SPICUR_08045
symbol: rlmH
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: SPICUR_08050
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: SPICUR_08055
symbol: nadD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: SPICUR_08060
symbol: proA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: SPICUR_08070
symbol: lptE
gene_biotype: protein_coding
description:
  Hypothetical protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: SPICUR_08085
symbol: lnt
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: SPICUR_08095
symbol: ybeY
gene_biotype: protein_coding
description:
  Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: SPICUR_08100
symbol: AGY91004.1
gene_biotype: protein_coding
description:
  Phosphate starvation protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_08105
symbol: miaB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: SPICUR_08110
symbol: AGY92577.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: SPICUR_08135
symbol: AGY91005.1
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: SPICUR_08155
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.


ensembl_gene_id: SPICUR_08160
symbol: rplQ
gene_biotype: protein_coding
description:
  50S ribosomal protein L17; Is a component of the macrolide binding site in the peptidyl transferase center; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL17 family.


ensembl_gene_id: SPICUR_08165
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SPICUR_08170
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: SPICUR_08175
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: SPICUR_08180
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: SPICUR_08185
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: SPICUR_08190
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: SPICUR_08200
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: SPICUR_08205
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: SPICUR_08210
symbol: AGY91012.1
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.


ensembl_gene_id: SPICUR_08215
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: SPICUR_08220
symbol: rpsN
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: SPICUR_08225
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: SPICUR_08230
symbol: rplX
gene_biotype: protein_coding
description:
  Hypothetical protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: SPICUR_08235
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: SPICUR_08240
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: SPICUR_08245
symbol: rpmC
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: SPICUR_08250
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: SPICUR_08255
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: SPICUR_08260
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: SPICUR_08265
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: SPICUR_08270
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: SPICUR_08275
symbol: rplW
gene_biotype: protein_coding
description:
  Hypothetical protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: SPICUR_08285
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: SPICUR_08290
symbol: rpsJ
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: SPICUR_08295
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: SPICUR_08300
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: SPICUR_08305
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: SPICUR_08310
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SPICUR_08320
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: SPICUR_08325
symbol: rplJ
gene_biotype: protein_coding
description:
  Hypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: SPICUR_08330
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: SPICUR_08335
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: SPICUR_08340
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: SPICUR_08355
symbol: AGY92604.1
gene_biotype: protein_coding
description:
  Elongation factor Tu; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_08385
symbol: AGY91025.1
gene_biotype: protein_coding
description:
  Bactoprenol glucosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_08400
symbol: AGY91026.1
gene_biotype: protein_coding
description:
  Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_08600
symbol: coaX
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: SPICUR_08635
symbol: tyrS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: SPICUR_08645
symbol: anmK
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: SPICUR_08655
symbol: argC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: SPICUR_08680
symbol: AGY92658.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: SPICUR_08685
symbol: rppH
gene_biotype: protein_coding
description:
  Hypothetical protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: SPICUR_08700
symbol: AGY92662.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: SPICUR_08715
symbol: purD
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GARS family.


ensembl_gene_id: SPICUR_08720
symbol: purH
gene_biotype: protein_coding
description:
  IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.


ensembl_gene_id: SPICUR_08725
symbol: AGY92666.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: SPICUR_08730
symbol: prmA
gene_biotype: protein_coding
description:
  Hypothetical protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: SPICUR_08735
symbol: AGY92668.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: SPICUR_08740
symbol: ppa
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: SPICUR_08745
symbol: pfp
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: SPICUR_08760
symbol: mpl
gene_biotype: protein_coding
description:
  Hypothetical protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: SPICUR_08775
symbol: thiE
gene_biotype: protein_coding
description:
  Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: SPICUR_08785
symbol: cpdA
gene_biotype: protein_coding
description:
  Hypothetical protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: SPICUR_08815
symbol: AGY92684.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: SPICUR_08840
symbol: dinB
gene_biotype: protein_coding
description:
  Hypothetical protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: SPICUR_08860
symbol: AGY92693.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: SPICUR_08880
symbol: AGY92697.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_08890
symbol: AGY92699.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_08910
symbol: AGY92703.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SPICUR_08920
symbol: glpK
gene_biotype: protein_coding
description:
  Hypothetical protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: SPICUR_08975
symbol: AGY92716.1
gene_biotype: protein_coding
description:
  NAD(P)H quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.


ensembl_gene_id: SPICUR_09030
symbol: apt
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: SPICUR_09060
symbol: ilvA
gene_biotype: protein_coding
description:
  L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: SPICUR_09065
symbol: rpiA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: SPICUR_09080
symbol: AGY92737.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the glutathione peroxidase family.


ensembl_gene_id: SPICUR_09100
symbol: AGY92741.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: SPICUR_09110
symbol: AGY92743.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the fructosamine kinase family.


ensembl_gene_id: SPICUR_09150
symbol: AGY92751.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: SPICUR_09260
symbol: gcvH
gene_biotype: protein_coding
description:
  Hypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: SPICUR_09275
symbol: AGY92776.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the UPF0149 family.


ensembl_gene_id: SPICUR_09285
symbol: AGY92778.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: SPICUR_09290
symbol: AGY92779.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: SPICUR_09305
symbol: argA
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: SPICUR_09320
symbol: lgt
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: SPICUR_09325
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: SPICUR_09330
symbol: AGY92786.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: SPICUR_09335
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: SPICUR_09340
symbol: AGY92788.1
gene_biotype: protein_coding
description:
  Thioredoxin; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thioredoxin family.


ensembl_gene_id: SPICUR_09345
symbol: cysQ
gene_biotype: protein_coding
description:
  Hypothetical protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: SPICUR_09395
symbol: engB
gene_biotype: protein_coding
description:
  Hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: SPICUR_09400
symbol: polA
gene_biotype: protein_coding
description:
  Hypothetical protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: SPICUR_09425
symbol: znuC
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: SPICUR_09475
symbol: glmS
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: SPICUR_09480
symbol: glmU
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: SPICUR_09485
symbol: atpC
gene_biotype: protein_coding
description:
  Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: SPICUR_09490
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: SPICUR_09495
symbol: atpG
gene_biotype: protein_coding
description:
  Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: SPICUR_09500
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: SPICUR_09505
symbol: atpH
gene_biotype: protein_coding
description:
  Hypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: SPICUR_09510
symbol: atpF
gene_biotype: protein_coding
description:
  Hypothetical protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: SPICUR_09515
symbol: atpE
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: SPICUR_09520
symbol: atpB
gene_biotype: protein_coding
description:
  Hypothetical protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: SPICUR_09530
symbol: AGY92825.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ParB family.


ensembl_gene_id: SPICUR_09540
symbol: rsmG
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: SPICUR_09545
symbol: mnmG
gene_biotype: protein_coding
description:
  Hypothetical protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: SPICUR_09550
symbol: mnmE
gene_biotype: protein_coding
description:
  Hypothetical protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: SPICUR_09555
symbol: yidC
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: SPICUR_09560
symbol: AGY92831.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: SPICUR_09565
symbol: rnpA
gene_biotype: protein_coding
description:
  Hypothetical protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: SPICUR_09570
symbol: rpmH
gene_biotype: protein_coding
description:
  50S ribosomal protein L34; In Escherichia coli transcription of this gene is enhanced by polyamines; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL34 family.


