# geneInfo

ensembl_gene_id: CLOST_0001
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: CLOST_0002
symbol: CBH20134.1
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: CLOST_0004
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: CLOST_0005
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase (subunit B); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: CLOST_0006
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase (type II topoisomerase), subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]


ensembl_gene_id: CLOST_0007
symbol: CBH20139.1
gene_biotype: protein_coding
description:
  Putative phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0008
symbol: CBH20140.1
gene_biotype: protein_coding
description:
  Putative exported protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0009
symbol: CBH20141.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0016
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: CLOST_0018
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: CLOST_0019
symbol: gatA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: CLOST_0020
symbol: gatB
gene_biotype: protein_coding
description:
  Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: CLOST_0021
symbol: pycA
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: CLOST_0022
symbol: CBH20152.1
gene_biotype: protein_coding
description:
  Putative Regulatory protein, TetR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0025
symbol: CBH20155.1
gene_biotype: protein_coding
description:
  Putative Abortive infection protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0030
symbol: yehX
gene_biotype: protein_coding
description:
  Putative transporter subunit: ATP-binding component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0033
symbol: CBH20163.1
gene_biotype: protein_coding
description:
  Putative Serine/threonine kinase, regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0035
symbol: sstT
gene_biotype: protein_coding
description:
  Sodium:serine/threonine symporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: CLOST_0039
symbol: yehW
gene_biotype: protein_coding
description:
  Putative transporter subunit: permease component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0040
symbol: yehZ
gene_biotype: protein_coding
description:
  Putative transporter subunit: periplasmic-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0041
symbol: speB
gene_biotype: protein_coding
description:
  Agmatinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the arginase family.


ensembl_gene_id: CLOST_0042
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: CLOST_0043
symbol: speH
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase alpha chain; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: CLOST_0044
symbol: speA
gene_biotype: protein_coding
description:
  Arginine decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0051
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: CLOST_0052
symbol: amyA
gene_biotype: protein_coding
description:
  Cytoplasmic alpha-amylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0053
symbol: CBH20183.1
gene_biotype: protein_coding
description:
  Putative Radical SAM domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0056
symbol: yjeM
gene_biotype: protein_coding
description:
  Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0061
symbol: CBH20191.1
gene_biotype: protein_coding
description:
  Putative S-adenosylmethionine-dependent methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0063
symbol: CBH20193.1
gene_biotype: protein_coding
description:
  Putative Acetyltransferase, GNAT family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0064
symbol: CBH20194.1
gene_biotype: protein_coding
description:
  Putative Similarities with helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0076
symbol: CBH20206.1
gene_biotype: protein_coding
description:
  Putative CobW/P47K family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0077
symbol: CBH20207.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the uroporphyrinogen decarboxylase family.


ensembl_gene_id: CLOST_0078
symbol: CBH20208.1
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase family protein; Belongs to the uroporphyrinogen decarboxylase family.


ensembl_gene_id: CLOST_0083
symbol: dppB
gene_biotype: protein_coding
description:
  Dipeptide transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0084
symbol: yliD
gene_biotype: protein_coding
description:
  Putative peptide transporter permease subunit: membrane component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0085
symbol: dppD
gene_biotype: protein_coding
description:
  Dipeptide transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: CLOST_0086
symbol: oppF
gene_biotype: protein_coding
description:
  Oligopeptide transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: CLOST_0089
symbol: metN
gene_biotype: protein_coding
description:
  DL-methionine transporter subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: CLOST_0090
symbol: metI
gene_biotype: protein_coding
description:
  DL-methionine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0091
symbol: CBH20221.1
gene_biotype: protein_coding
description:
  Putative D-methionine-binding lipoprotein metQ precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0092
symbol: CBH20222.1
gene_biotype: protein_coding
description:
  Putative Methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the uroporphyrinogen decarboxylase family.


ensembl_gene_id: CLOST_0095
symbol: ywjA
gene_biotype: protein_coding
description:
  Putative ABC lipid transporter (ATP-binding protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0098
symbol: CBH20228.1
gene_biotype: protein_coding
description:
  Putative Peptidase U32; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0100
symbol: pdxT
gene_biotype: protein_coding
description:
  Glutamine amidotransferase subunit pdxT (Glutamine amidotransferase glutaminase subunit pdxT); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: CLOST_0101
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: CLOST_0103
symbol: yaaJ
gene_biotype: protein_coding
description:
  YaaJ; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: CLOST_0106
symbol: cdu
gene_biotype: protein_coding
description:
  Putative Na(+)/H(+) antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0108
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: CLOST_0109
symbol: CBH20239.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: CLOST_0110
symbol: recR
gene_biotype: protein_coding
description:
  Gap repair protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: CLOST_0112
symbol: malR
gene_biotype: protein_coding
description:
  Putative regulatory protein malR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0115
symbol: CBH20245.1
gene_biotype: protein_coding
description:
  Putative Nitroimidazole resistance protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0120
symbol: pcp
gene_biotype: protein_coding
description:
  Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.


ensembl_gene_id: CLOST_0121
symbol: CBH20251.1
gene_biotype: protein_coding
description:
  CRP/FNR family transcriptional regulator, cyclic AMP receptor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0122
symbol: CBH20252.1
gene_biotype: protein_coding
description:
  Putative membrane-associated protease (CAAX amino terminal protease family protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0130
symbol: CBH20260.1
gene_biotype: protein_coding
description:
  Putative Response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0133
symbol: ybiT
gene_biotype: protein_coding
description:
  Putative transporter fused subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0136
symbol: astC
gene_biotype: protein_coding
description:
  Succinylornithine transaminase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: CLOST_0137
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: CLOST_0138
symbol: argJ
gene_biotype: protein_coding
description:
  ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: CLOST_0139
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamylphosphate reductase, NAD(P)-binding; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: CLOST_0140
symbol: argH
gene_biotype: protein_coding
description:
  Argininosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0141
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: CLOST_0144
symbol: CBH20274.1
gene_biotype: protein_coding
description:
  Putative 5-methyltetrahydrofolate--homocysteine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0152
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: CLOST_0153
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: CLOST_0159
symbol: mcsB
gene_biotype: protein_coding
description:
  McsB; Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family.


ensembl_gene_id: CLOST_0160
symbol: clpB
gene_biotype: protein_coding
description:
  Protein disaggregation chaperone; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the ClpA/ClpB family.


ensembl_gene_id: CLOST_0161
symbol: radA
gene_biotype: protein_coding
description:
  Repair protein radA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: CLOST_0167
symbol: CBH20297.1
gene_biotype: protein_coding
description:
  Putative Starch synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0169
symbol: pepA
gene_biotype: protein_coding
description:
  Putative cytosol aminopeptidase (Leucine aminopeptidase) (LAP) (Leucyl aminopeptidase); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: CLOST_0170
symbol: CBH20300.1
gene_biotype: protein_coding
description:
  Putative 50S ribosomal protein L25 1 (General stress protein CTC 1); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: CLOST_0172
symbol: CBH20302.1
gene_biotype: protein_coding
description:
  Putative NADH oxidase (NOXase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0174
symbol: CBH20304.1
gene_biotype: protein_coding
description:
  Putative Alpha-amylase precursor (1, 4-alpha-D-glucan glucanohydrolase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0175
symbol: CBH20305.1
gene_biotype: protein_coding
description:
  Putative MutS family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: CLOST_0177
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: CLOST_0183
symbol: CBH20313.1
gene_biotype: protein_coding
description:
  ApbE family protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: CLOST_0185
symbol: yggR
gene_biotype: protein_coding
description:
  Transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0187
symbol: CBH20317.1
gene_biotype: protein_coding
description:
  Putative Fimbrial protein precursor (Pilin) (Strain K122-4); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0191
symbol: CBH20321.1
gene_biotype: protein_coding
description:
  Putative Type IV pilus assembly protein PilM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0195
symbol: kduD
gene_biotype: protein_coding
description:
  2-deoxy-D-gluconate 3-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0201
symbol: CBH20331.1
gene_biotype: protein_coding
description:
  Putative NADPH-dependent FMN reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0205
symbol: CBH20335.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate protein domain protein TPP-binding; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: CLOST_0207
symbol: CBH20337.1
gene_biotype: protein_coding
description:
  Putative membrane protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0208
symbol: buk
gene_biotype: protein_coding
description:
  Branched-chain fatty-acid kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the acetokinase family.


ensembl_gene_id: CLOST_0213
symbol: yvrO
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0215
symbol: CBH20345.1
gene_biotype: protein_coding
description:
  Putative Efflux transporter, RND family, MFP subunit precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: CLOST_0217
symbol: CBH20347.1
gene_biotype: protein_coding
description:
  Putative cell division protein ftsh; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the AAA ATPase family.


ensembl_gene_id: CLOST_0220
symbol: CBH20350.1
gene_biotype: protein_coding
description:
  Putative Type IV fimbrial biogenesis protein, prepilin cysteine protease (C20) PilD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0230
symbol: ykfB
gene_biotype: protein_coding
description:
  Putative muconate cycloisomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0231
symbol: hcp
gene_biotype: protein_coding
description:
  Hybrid-cluster [4Fe-2S-2O] protein in anaerobic terminal reductases; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.


ensembl_gene_id: CLOST_0237
symbol: CBH20367.1
gene_biotype: protein_coding
description:
  Putative permease (Major facilitator superfamily); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0242
symbol: ypfE
gene_biotype: protein_coding
description:
  Putative carboxysome-like ethanolaminosome structural protein with role in ethanol utilization; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: CLOST_0246
symbol: eutA
gene_biotype: protein_coding
description:
  Reactivating factor for ethanolamine ammonia lyase; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: CLOST_0247
symbol: eutB
gene_biotype: protein_coding
description:
  Ethanolamine ammonia-lyase, large subunit, heavy chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0248
symbol: eutC
gene_biotype: protein_coding
description:
  Ethanolamine ammonia-lyase light chain (Ethanolamine ammonia-lyase small subunit); Belongs to the EutC family.


ensembl_gene_id: CLOST_0249
symbol: eutL
gene_biotype: protein_coding
description:
  Putative carboxysome-related structural protein with role in ethanolamine utilization; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: CLOST_0252
symbol: cchA
gene_biotype: protein_coding
description:
  Putative carboxysome-like ethanolaminosome structural protein, ethanolamine utilization protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: CLOST_0253
symbol: eutT
gene_biotype: protein_coding
description:
  Putative cobalamin adenosyltransferase in ethanolamine utilization; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0256
symbol: eutH
gene_biotype: protein_coding
description:
  Putative ethanolamine transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0258
symbol: eutJ
gene_biotype: protein_coding
description:
  Putative chaperonin, ethanolamine utilization protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: CLOST_0262
symbol: tyrS
gene_biotype: protein_coding
description:
  Tyrosyl-tRNA synthetase 1 (Tyrosine--tRNA ligase 1) (TyrRS 1); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: CLOST_0265
symbol: feoB
gene_biotype: protein_coding
description:
  Fused ferrous iron transporter, protein B: GTP-binding protein; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: CLOST_0270
symbol: CBH20400.1
gene_biotype: protein_coding
description:
  Putative enzyme; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.


ensembl_gene_id: CLOST_0272
symbol: CBH20402.1
gene_biotype: protein_coding
description:
  Putative universal stress protein family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0273
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase, catalytic subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: CLOST_0274
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: CLOST_0275
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase (OMP decarboxylase) (OMPDCase) (OMPdecase); Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: CLOST_0278
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase (OPRT) (OPRTase); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: CLOST_0282
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: CLOST_0283
symbol: CBH20413.1
gene_biotype: protein_coding
description:
  Putative DNA glycosylase (DNA repair protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0284
symbol: ywnE
gene_biotype: protein_coding
description:
  YwnE; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: CLOST_0285
symbol: groS
gene_biotype: protein_coding
description:
  Cpn10 chaperonin GroES, small subunit of GroESL; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: CLOST_0286
symbol: groL
gene_biotype: protein_coding
description:
  Cpn60 chaperonin GroEL, large subunit of GroESL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: CLOST_0288
symbol: larC
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.


ensembl_gene_id: CLOST_0290
symbol: mdlB
gene_biotype: protein_coding
description:
  Putative fused ATPase and permease component of metabolite ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0296
symbol: guaB
gene_biotype: protein_coding
description:
  IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: CLOST_0302
symbol: CBH20432.1
gene_biotype: protein_coding
description:
  Putative phage DNA-polymerase or DNA-primase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0306
symbol: CBH20436.1
gene_biotype: protein_coding
description:
  Putative conjugative transposon mobilization protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0318
symbol: CBH20448.1
gene_biotype: protein_coding
description:
  Putative Manganese-dependent inorganic pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0322
symbol: CBH20452.1
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0323
symbol: CBH20453.1
gene_biotype: protein_coding
description:
  Putative Chromosome partitioning ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0333
symbol: purE
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: CLOST_0334
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SAICAR synthetase family.


ensembl_gene_id: CLOST_0335
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: CLOST_0336
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0337
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: CLOST_0338
symbol: purH
gene_biotype: protein_coding
description:
  Fused IMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0342
symbol: hupB
gene_biotype: protein_coding
description:
  HU, DNA-binding transcriptional regulator, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: CLOST_0345
symbol: CBH20475.1
gene_biotype: protein_coding
description:
  Putative exopolyphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0359
symbol: CBH20489.1
gene_biotype: protein_coding
description:
  Putative capsular polysaccharide biosynthesis glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0366
symbol: epsM
gene_biotype: protein_coding
description:
  Putative O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0369
symbol: neuA
gene_biotype: protein_coding
description:
  CMP-N,N'-diacetyllegionaminic acid synthase; N-acylneuraminate cytidylyltransferase (CMP-N-acetylneuraminic acid synthetase) (CMP-NeuNAc synthetase) (CMP-sialic acid synthetase).


ensembl_gene_id: CLOST_0370
symbol: murJ
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: CLOST_0378
symbol: CBH20508.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator (fragment); Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_0379
symbol: CBH20509.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter, permease protein (fragment); Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_0380
symbol: CBH20510.1
gene_biotype: protein_coding
description:
  Putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0384
symbol: hscC
gene_biotype: protein_coding
description:
  Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the heat shock protein 70 family.


ensembl_gene_id: CLOST_0386
symbol: CBH20516.1
gene_biotype: protein_coding
description:
  Putative translation initiation factor EIF-2B subunit 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: CLOST_0387
symbol: mtnK
gene_biotype: protein_coding
description:
  5-methylribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.


ensembl_gene_id: CLOST_0393
symbol: CBH20523.1
gene_biotype: protein_coding
description:
  Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase M24B family.


ensembl_gene_id: CLOST_0396
symbol: ykbA
gene_biotype: protein_coding
description:
  Putative amino acid permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: CLOST_0401
symbol: yveM
gene_biotype: protein_coding
description:
  Putative capsular polysaccharide biosynthesis protein YveM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0408
symbol: yjbJ
gene_biotype: protein_coding
description:
  Putative stress response protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: CLOST_0409
symbol: rmlA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: CLOST_0410
symbol: ribD
gene_biotype: protein_coding
description:
  Fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: CLOST_0411
symbol: ribE
gene_biotype: protein_coding
description:
  Riboflavin synthase (alpha subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0412
symbol: ribBA
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: CLOST_0413
symbol: ribE-2
gene_biotype: protein_coding
description:
  Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: CLOST_0414
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: CLOST_0415
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate isomerase subunit, dehydratase component; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: CLOST_0416
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.


ensembl_gene_id: CLOST_0417
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: CLOST_0418
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: CLOST_0419
symbol: CBH20549.1
gene_biotype: protein_coding
description:
  Putative Serine phosphatase precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0420
symbol: CBH20550.1
gene_biotype: protein_coding
description:
  Putative Multiple antibiotic resistance protein marR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0423
symbol: CBH20553.1
gene_biotype: protein_coding
description:
  Putative Secretion protein HlyD family protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0426
symbol: gcvT
gene_biotype: protein_coding
description:
  Aminomethyltransferase, tetrahydrofolate-dependent, subunit (T protein) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: CLOST_0427
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: CLOST_0428
symbol: gcvPA
gene_biotype: protein_coding
description:
  Probable glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: CLOST_0429
symbol: gcvPB
gene_biotype: protein_coding
description:
  GcvPB; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.


ensembl_gene_id: CLOST_0430
symbol: yhdR
gene_biotype: protein_coding
description:
  Putative aspartate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0432
symbol: CBH20562.1
gene_biotype: protein_coding
description:
  Putative Glutaminyl-peptide cyclotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0434
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: CLOST_0435
symbol: rmlB
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6 dehydratase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: CLOST_0440
symbol: CBH20570.1
gene_biotype: protein_coding
description:
  Putative ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0443
symbol: CBH20573.1
gene_biotype: protein_coding
description:
  Putative Galactoside O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0444
symbol: yfdH
gene_biotype: protein_coding
description:
  Bactoprenol glucosyl transferase; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin.


ensembl_gene_id: CLOST_0447
symbol: eryC
gene_biotype: protein_coding
description:
  Erythromycin biosynthesis sensory transduction protein eryC1; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: CLOST_0452
symbol: yknY
gene_biotype: protein_coding
description:
  ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: CLOST_0455
symbol: CBH20585.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, TetR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0457
symbol: CBH20587.1
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: CLOST_0460
symbol: galU
gene_biotype: protein_coding
description:
  Glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0462
symbol: fsaB
gene_biotype: protein_coding
description:
  Fructose-6-phosphate aldolase 2; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: CLOST_0463
symbol: yueK
gene_biotype: protein_coding
description:
  YueK; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: CLOST_0464
symbol: metS
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: CLOST_0467
symbol: rnmV
gene_biotype: protein_coding
description:
  Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.


ensembl_gene_id: CLOST_0468
symbol: ksgA
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: CLOST_0469
symbol: murC
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate--L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase); Cell wall formation; Belongs to the MurCDEF family.


ensembl_gene_id: CLOST_0470
symbol: purR
gene_biotype: protein_coding
description:
  Transcriptional regulator of the purine biosynthesis operon; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_0472
symbol: glmU
gene_biotype: protein_coding
description:
  Fused N-acetyl glucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: CLOST_0473
symbol: prsA
gene_biotype: protein_coding
description:
  Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: CLOST_0474
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: CLOST_0475
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: CLOST_0476
symbol: prsA-2
gene_biotype: protein_coding
description:
  Putative foldase lipoprotein (Late stage protein export lipoprotein) precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0477
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: CLOST_0484
symbol: dacA
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.


ensembl_gene_id: CLOST_0488
symbol: buk-3
gene_biotype: protein_coding
description:
  Putative butyrate kinase (BK) (Branched-chain carboxylic acid kinase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the acetokinase family.


ensembl_gene_id: CLOST_0489
symbol: CBH20615.1
gene_biotype: protein_coding
description:
  Putative ATP/GTP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0491
symbol: vorB
gene_biotype: protein_coding
description:
  Ketoisovalerate oxidoreductase subunit vorB (VOR) (2-oxoisovalerate oxidoreductase beta chain) (2-oxoisovalerate ferredoxin reductase subunit beta).


ensembl_gene_id: CLOST_0492
symbol: CBH20618.1
gene_biotype: protein_coding
description:
  Putative subunit of oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0497
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: CLOST_0498
symbol: glmS
gene_biotype: protein_coding
description:
  L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: CLOST_0500
symbol: CBH20626.1
gene_biotype: protein_coding
description:
  Putative Metal dependent phosphohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0504
symbol: CBH20630.1
gene_biotype: protein_coding
description:
  Putative Hemerythrin HHE cation binding region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0505
symbol: CBH20631.1
gene_biotype: protein_coding
description:
  Putative Oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0506
symbol: dsdA
gene_biotype: protein_coding
description:
  D-serine ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the serine/threonine dehydratase family. DsdA subfamily.


ensembl_gene_id: CLOST_0507
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinulease of nucleotide excision repair, DNA damage recognition component; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. I [...]


ensembl_gene_id: CLOST_0508
symbol: uvrA
gene_biotype: protein_coding
description:
  ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: CLOST_0520
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase (ATP-PRTase) (ATP-PRT); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: CLOST_0521
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase and histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: CLOST_0522
symbol: CBH20648.1
gene_biotype: protein_coding
description:
  Putative Histidinol-phosphate aminotransferase 1 (Imidazole acetol-phosphate transaminase 1); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0524
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit with HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: CLOST_0525
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase (Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase).


ensembl_gene_id: CLOST_0526
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, catalytic subunit with HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: CLOST_0527
symbol: hisI
gene_biotype: protein_coding
description:
  Phosphoribosyl-AMP cyclohydrolase (PRA-CH); Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family.


ensembl_gene_id: CLOST_0533
symbol: CBH20659.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, PadR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0535
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: CLOST_0536
symbol: yjgF
gene_biotype: protein_coding
description:
  Ketoacid-binding protein; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme.


ensembl_gene_id: CLOST_0537
symbol: ydgJ
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0540
symbol: CBH20666.1
gene_biotype: protein_coding
description:
  Putative Response regulator receiver protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0541
symbol: xylF
gene_biotype: protein_coding
description:
  D-xylose transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0543
symbol: xylG
gene_biotype: protein_coding
description:
  Fused D-xylose transporter subunits of ABC superfamily: ATP-binding components; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0544
symbol: xylH
gene_biotype: protein_coding
description:
  D-xylose transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_0545
symbol: ysdA
gene_biotype: protein_coding
description:
  Putative membrane component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: CLOST_0547
symbol: uvrC
gene_biotype: protein_coding
description:
  UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: CLOST_0548
symbol: hprK
gene_biotype: protein_coding
description:
  HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...]


ensembl_gene_id: CLOST_0553
symbol: CBH20679.1
gene_biotype: protein_coding
description:
  Putative phospholipase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0554
symbol: CBH20680.1
gene_biotype: protein_coding
description:
  Putative Nitroreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0555
symbol: pcrA
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0556
symbol: apeB
gene_biotype: protein_coding
description:
  Putative M18 family aminopeptidase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0567
symbol: zntA
gene_biotype: protein_coding
description:
  Zinc, cobalt and lead efflux system; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0569
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase B (rotamase B); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: CLOST_0570
symbol: CBH20696.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulphide oxidoreductase precursor; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: CLOST_0572
symbol: ltaE
gene_biotype: protein_coding
description:
  L-allo-threonine aldolase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0573
symbol: CBH20699.1
gene_biotype: protein_coding
description:
  Putative lipid kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0575
symbol: CBH20701.1
gene_biotype: protein_coding
description:
  Putative pirin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the pirin family.


ensembl_gene_id: CLOST_0579
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD(+)-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: CLOST_0581
symbol: oppB
gene_biotype: protein_coding
description:
  Oligopeptide transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0587
symbol: CBH20713.1
gene_biotype: protein_coding
description:
  Putative N-acetylmuramoyl-L-alanine amidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0588
symbol: rph
gene_biotype: protein_coding
description:
  Nucleoside-triphosphatase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: CLOST_0589
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor (TF); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: CLOST_0590
symbol: clpP
gene_biotype: protein_coding
description:
  Proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: CLOST_0591
symbol: clpX
gene_biotype: protein_coding
description:
  ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: CLOST_0593
symbol: lon
gene_biotype: protein_coding
description:
  DNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: CLOST_0594
symbol: yihA
gene_biotype: protein_coding
description:
  GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: CLOST_0597
symbol: CBH20723.1
gene_biotype: protein_coding
description:
  Putative Monogalactosyldiacylglycerol synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0601
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI); Belongs to the GPI family.


ensembl_gene_id: CLOST_0603
symbol: CBH20729.1
gene_biotype: protein_coding
description:
  Putative ABC transporter-binding protein DR_1438 precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0604
symbol: CBH20730.1
gene_biotype: protein_coding
description:
  Proton/glutamate symporter family protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: CLOST_0605
symbol: znuC
gene_biotype: protein_coding
description:
  Zinc transporter subunit: ATP-binding component of ABC superfamily; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0607
symbol: CBH20733.1
gene_biotype: protein_coding
description:
  Putative Zur; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the Fur family.


ensembl_gene_id: CLOST_0612
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: CLOST_0614
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transporter subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: CLOST_0615
symbol: phoU
gene_biotype: protein_coding
description:
  Phosphate transport system regulatory protein PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: CLOST_0622
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: CLOST_0628
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: CLOST_0629
symbol: CBH20755.1
gene_biotype: protein_coding
description:
  Putative amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0630
symbol: CBH20756.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0637
symbol: CBH20763.1
gene_biotype: protein_coding
description:
  Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0638
symbol: hslO
gene_biotype: protein_coding
description:
  Disulfide bond chaperone (heat shock protein HSP33); Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: CLOST_0642
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: CLOST_0643
symbol: pgk
gene_biotype: protein_coding
description:
  Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: CLOST_0644
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: CLOST_0645
symbol: gpmI
gene_biotype: protein_coding
description:
  Phosphoglycero mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: CLOST_0646
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: CLOST_0647
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: CLOST_0648
symbol: hppA
gene_biotype: protein_coding
description:
  Putative K(+)-stimulated pyrophosphate-energized sodium pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.


ensembl_gene_id: CLOST_0651
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: CLOST_0654
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: CLOST_0655
symbol: vacB
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: CLOST_0657
symbol: smpB
gene_biotype: protein_coding
description:
  Trans-translation protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...]


ensembl_gene_id: CLOST_0664
symbol: iadA
gene_biotype: protein_coding
description:
  Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belongs to the peptidase M38 family.


ensembl_gene_id: CLOST_0667
symbol: CBH20793.1
gene_biotype: protein_coding
description:
  Putative DAK2 domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0671
symbol: CBH20797.1
gene_biotype: protein_coding
description:
  Putative YqjE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0674
symbol: eutE
gene_biotype: protein_coding
description:
  Putative aldehyde dehydrogenase, ethanolamine utilization protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0677
symbol: CBH20803.1
gene_biotype: protein_coding
description:
  Putative Microcompartments protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0679
symbol: CBH20805.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.


ensembl_gene_id: CLOST_0683
symbol: CBH20809.1
gene_biotype: protein_coding
description:
  Putative Coenzyme A transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0684
symbol: CBH20810.1
gene_biotype: protein_coding
description:
  Putative glutaconate CoA-transferase, subunit B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0686
symbol: rbsA
gene_biotype: protein_coding
description:
  Fused D-ribose transporter subunits of ABC superfamily: ATP-binding components; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0687
symbol: CBH20813.1
gene_biotype: protein_coding
description:
  Methylthioribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_0689
symbol: mtnA
gene_biotype: protein_coding
description:
  Putative Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: CLOST_0693
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: CLOST_0698
symbol: CBH20824.1
gene_biotype: protein_coding
description:
  Putative Methyltransferase type 12; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0702
symbol: ybaJ
gene_biotype: protein_coding
description:
  Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0717
symbol: ywgB
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0720
symbol: CBH20846.1
gene_biotype: protein_coding
description:
  Protein of unknown function; No homology to any previously reported sequences; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: CLOST_0721
symbol: CBH20847.1
gene_biotype: protein_coding
description:
  Putative Acriflavin resistance protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: CLOST_0723
symbol: deoD
gene_biotype: protein_coding
description:
  Purine-nucleoside phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0743
symbol: CBH20869.1
gene_biotype: protein_coding
description:
  Putative glutamine amidotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0745
symbol: CBH20871.1
gene_biotype: protein_coding
description:
  Putative sigma-54-dependent transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0746
symbol: sbcD
gene_biotype: protein_coding
description:
  Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: CLOST_0747
symbol: CBH20873.1
gene_biotype: protein_coding
description:
  Putative Nuclease sbcCD subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0749
symbol: norV
gene_biotype: protein_coding
description:
  Flavorubredoxin oxidoreductase; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: CLOST_0752
symbol: CBH20878.1
gene_biotype: protein_coding
description:
  Putative IclR family transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0753
symbol: porC
gene_biotype: protein_coding
description:
  Pyruvate synthase subunit porC (Pyruvate oxidoreductase gamma chain) (POR) (Pyruvic-ferredoxin oxidoreductase subunit gamma).


ensembl_gene_id: CLOST_0755
symbol: porA
gene_biotype: protein_coding
description:
  Pyruvate synthase subunit porA (Pyruvate oxidoreductase alpha chain) (POR) (Pyruvic-ferredoxin oxidoreductase subunit alpha).


ensembl_gene_id: CLOST_0768
symbol: arsB
gene_biotype: protein_coding
description:
  Arsenite efflux transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0769
symbol: CBH20895.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0772
symbol: rbsC
gene_biotype: protein_coding
description:
  D-ribose transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_0774
symbol: ydjJ
gene_biotype: protein_coding
description:
  Putative iditol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0776
symbol: CBH20902.1
gene_biotype: protein_coding
description:
  Putative iron-sulfur protein (Cysteine-rich domain protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0780
symbol: fbpC
gene_biotype: protein_coding
description:
  Ferric transporter subunit; Function of strongly homologous gene; transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: CLOST_0781
symbol: CBH20907.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: CLOST_0784
symbol: CBH20910.1
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0787
symbol: CBH20913.1
gene_biotype: protein_coding
description:
  Putative ABC-type antimicrobial peptide transport system, ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0792
symbol: CBH20918.1
gene_biotype: protein_coding
description:
  Putative GCN5-related N-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0801
symbol: CBH20927.1
gene_biotype: protein_coding
description:
  Nitrite and sulphite reductase 4Fe-4S region; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: CLOST_0804
symbol: hutI
gene_biotype: protein_coding
description:
  Putative imidazolonepropionase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0822
symbol: CBH20948.1
gene_biotype: protein_coding
description:
  Putative radical SAM family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0823
symbol: CBH20949.1
gene_biotype: protein_coding
description:
  Putative SpeA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0829
symbol: fdhA
gene_biotype: protein_coding
description:
  Formate dehydrogenase alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: CLOST_0830
symbol: fdhB
gene_biotype: protein_coding
description:
  Formate dehydrogenase-H, [4Fe-4S] ferredoxin subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: CLOST_0831
symbol: CBH20956.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0833
symbol: rsmH
gene_biotype: protein_coding
description:
  Methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: CLOST_0836
symbol: moeA
gene_biotype: protein_coding
description:
  MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: CLOST_0837
symbol: CBH20962.1
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase accessory protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family.


ensembl_gene_id: CLOST_0838
symbol: yiaI
gene_biotype: protein_coding
description:
  Putative hydrogenase, 4Fe-4S ferredoxin-type component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: CLOST_0841
symbol: mobA
gene_biotype: protein_coding
description:
  Putative molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.


ensembl_gene_id: CLOST_0845
symbol: hydF
gene_biotype: protein_coding
description:
  Iron-only hydrogenase maturation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0846
symbol: hydG
gene_biotype: protein_coding
description:
  Fe-hydrogenase assembly protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0853
symbol: nagBA
gene_biotype: protein_coding
description:
  N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: CLOST_0854
symbol: CBH20979.1
gene_biotype: protein_coding
description:
  Putative Methyltransferase type 11; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0855
symbol: CBH20980.1
gene_biotype: protein_coding
description:
  Putative Metal-dependent phosphohydrolase, HD region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0856
symbol: CBH20981.1
gene_biotype: protein_coding
description:
  Putative Type II secretion system protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0862
symbol: CBH20987.1
gene_biotype: protein_coding
description:
  Putative Transglutaminase-like enzyme, cysteine protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0863
symbol: CBH20988.1
gene_biotype: protein_coding
description:
  Putative hesB/yadR/yfhF family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the HesB/IscA family.


ensembl_gene_id: CLOST_0865
symbol: cspA
gene_biotype: protein_coding
description:
  Major cold shock protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: CLOST_0868
symbol: bipA
gene_biotype: protein_coding
description:
  GTP-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: CLOST_0869
symbol: baeR
gene_biotype: protein_coding
description:
  DNA-binding response regulator in two-component regulatory system with BaeS; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_0870
symbol: CBH20995.1
gene_biotype: protein_coding
description:
  Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0872
symbol: tupA
gene_biotype: protein_coding
description:
  ABC-type tungstate transport system, permease component; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0873
symbol: tupB
gene_biotype: protein_coding
description:
  ABC-type tungstate transport permease protein; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0874
symbol: tupC
gene_biotype: protein_coding
description:
  ABC-type tungstate transport system, ATPase component; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0882
symbol: CBH21007.1
gene_biotype: protein_coding
description:
  Putative Phosphoserine phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0883
symbol: CBH21008.1
gene_biotype: protein_coding
description:
  Putative Peptidase M23B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0887
symbol: CBH21012.1
gene_biotype: protein_coding
description:
  Putative RNA methylase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0889
symbol: accB
gene_biotype: protein_coding
description:
  Acetyl CoA carboxylase, BCCP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: CLOST_0890
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: CLOST_0891
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, beta (carboxyltranferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: CLOST_0892
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: CLOST_0894
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: CLOST_0897
symbol: fabD
gene_biotype: protein_coding
description:
  malonyl-CoA-[acyl-carrier-protein] transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_0898
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: CLOST_0899
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: CLOST_0900
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: CLOST_0902
symbol: CBH21027.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the glycosyl hydrolase 26 family.


ensembl_gene_id: CLOST_0904
symbol: CBH21029.1
gene_biotype: protein_coding
description:
  Putative Exopolyphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0906
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase, component of RNA degradosome; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: CLOST_0907
symbol: hymC
gene_biotype: protein_coding
description:
  Putative catalytic subunit of iron-only hydrogenase ([Fe] hydrogenase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0908
symbol: hymB
gene_biotype: protein_coding
description:
  Putative [Fe] hydrogenase, electron-transfer subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0909
symbol: hymA
gene_biotype: protein_coding
description:
  Putative Fe hydrogenase, electron-transfer subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: CLOST_0910
symbol: nror
gene_biotype: protein_coding
description:
  NADH:Rubredoxin oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; carrier.


ensembl_gene_id: CLOST_0912
symbol: CBH21037.1
gene_biotype: protein_coding
description:
  Putative pseudouridylate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0915
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: CLOST_0919
symbol: CBH21044.1
gene_biotype: protein_coding
description:
  Putative Zinc metallohydrolase, glyoxalase II family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0920
symbol: CBH21045.1
gene_biotype: protein_coding
description:
  Putative guanosine 3',5'-bis-pyrophosphate (PpGpp) synthesis/degradation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0921
symbol: CBH21046.1
gene_biotype: protein_coding
description:
  Putative phosphoesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0922
symbol: pfp
gene_biotype: protein_coding
description:
  Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: CLOST_0925
symbol: CBH21050.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, MerR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0927
symbol: arcB
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase 1; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: CLOST_0928
symbol: arcC
gene_biotype: protein_coding
description:
  Carbamate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbamate kinase family.


ensembl_gene_id: CLOST_0929
symbol: CBH21054.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0931
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: CLOST_0933
symbol: ddlA
gene_biotype: protein_coding
description:
  D-alanine-D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: CLOST_0936
symbol: tilS
gene_biotype: protein_coding
description:
  tRNAile lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: CLOST_0937
symbol: ftsH
gene_biotype: protein_coding
description:
  Protease, ATP-dependent zinc-metallo; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: CLOST_0940
symbol: argK
gene_biotype: protein_coding
description:
  Membrane ATPase/protein kinase; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_0941
symbol: yqjC
gene_biotype: protein_coding
description:
  Putative lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0943
symbol: CBH21068.1
gene_biotype: protein_coding
description:
  Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family.


ensembl_gene_id: CLOST_0945
symbol: oadB
gene_biotype: protein_coding
description:
  Oxaloacetate decarboxylase beta chain; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).


ensembl_gene_id: CLOST_0946
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


ensembl_gene_id: CLOST_0950
symbol: CBH21075.1
gene_biotype: protein_coding
description:
  Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: CLOST_0951
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: CLOST_0952
symbol: lysU
gene_biotype: protein_coding
description:
  Lysine tRNA synthetase, inducible; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: CLOST_0955
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: CLOST_0957
symbol: nrdG
gene_biotype: protein_coding
description:
  Anaerobic ribonucleotide reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: CLOST_0965
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: CLOST_0967
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: CLOST_0970
symbol: glgP
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: CLOST_0971
symbol: CBH21094.1
gene_biotype: protein_coding
description:
  Putative alpha-amylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0978
symbol: btuE
gene_biotype: protein_coding
description:
  Putative glutathione peroxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glutathione peroxidase family.


ensembl_gene_id: CLOST_0979
symbol: CBH21102.1
gene_biotype: protein_coding
description:
  Putative phosphoserine phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0981
symbol: cobB
gene_biotype: protein_coding
description:
  Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: CLOST_0982
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: CLOST_0985
symbol: cobD-2
gene_biotype: protein_coding
description:
  Putative threonine-phosphate decarboxylase (L-threonine-O-3-phosphate decarboxylase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0986
symbol: pduX
gene_biotype: protein_coding
description:
  Putative L-threonine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_0988
symbol: cbiD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: CLOST_0989
symbol: CBH21112.1
gene_biotype: protein_coding
description:
  Cobalt-precorrin-7 (C5)-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0990
symbol: cobL
gene_biotype: protein_coding
description:
  Putative Precorrin-6B methylase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0992
symbol: cbiF
gene_biotype: protein_coding
description:
  Cobalt-precorrin-4 C(11)-methyltransferase (Cobalt-precorrin-3 methylase); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: CLOST_0993
symbol: CBH21116.1
gene_biotype: protein_coding
description:
  Putative Protein cbiG; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_0994
symbol: cbiH
gene_biotype: protein_coding
description:
  Cobalt-precorrin-3B C(17)-methyltransferase (Cobalt-precorrin-3 methyltransferase) (Cobalt-precorrin-3 methylase).


ensembl_gene_id: CLOST_0996
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: CLOST_0998
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: CLOST_1000
symbol: hemB
gene_biotype: protein_coding
description:
  Porphobilinogen synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family.


ensembl_gene_id: CLOST_1001
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde aminotransferase (aminomutase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1003
symbol: CBH21126.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator precursor; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_1021
symbol: npdA
gene_biotype: protein_coding
description:
  NAD-dependent deacetylase (Regulatory protein SIR2 homolog); NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.


ensembl_gene_id: CLOST_1023
symbol: mutX
gene_biotype: protein_coding
description:
  8-oxo-dGTP diphosphatase; Mutator mutT protein (7, 8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dGTPase) (dGTP pyrophosphohydrolase).


ensembl_gene_id: CLOST_1024
symbol: CBH21147.1
gene_biotype: protein_coding
description:
  Putative iron-sulfur-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1042
symbol: CBH21165.1
gene_biotype: protein_coding
description:
  Putative metal dependent phosphohydrolase (HD domain protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1046
symbol: CBH21169.1
gene_biotype: protein_coding
description:
  Putative helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1050
symbol: CBH21173.1
gene_biotype: protein_coding
description:
  Putative Major facilitator superfamily MFS_1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1057
symbol: grdH
gene_biotype: protein_coding
description:
  Betaine reductase complex component B subunit beta (Selenoprotein PB beta); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1059
symbol: opuD
gene_biotype: protein_coding
description:
  Glycine betaine transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: CLOST_1061
symbol: CBH21183.1
gene_biotype: protein_coding
description:
  Conserved membrane protein of unknown function; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: CLOST_1065
symbol: CBH21187.1
gene_biotype: protein_coding
description:
  Putative glycosyl transferase (Glycosyl transferase, group 1 family protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1067
symbol: CBH21189.1
gene_biotype: protein_coding
description:
  Putative fumarate hydratase subunit beta (Fumarase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1068
symbol: CBH21190.1
gene_biotype: protein_coding
description:
  Putative fumarate hydratase subunit alpha (Fumarase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1071
symbol: CBH21193.1
gene_biotype: protein_coding
description:
  Putative CoA-substrate-specific enzyme activase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1072
symbol: yvdE
gene_biotype: protein_coding
description:
  Putative glutamine amidotransferase-like protein yvdE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1077
symbol: ypdB
gene_biotype: protein_coding
description:
  Putative response regulator in two-component system with YpdA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: CLOST_1078
symbol: ypdA
gene_biotype: protein_coding
description:
  Putative sensory kinase in two-component system with YpdB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.


ensembl_gene_id: CLOST_1079
symbol: glnS
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1082
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A 2 (tRNA-uridine isomerase I 2) (tRNA pseudouridylate synthase I 2); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: CLOST_1083
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: CLOST_1084
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA-glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: CLOST_1087
symbol: CBH21209.1
gene_biotype: protein_coding
description:
  Putative Myo-inositol-1(or 4)-monophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: CLOST_1090
symbol: zupT
gene_biotype: protein_coding
description:
  Putative dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1097
symbol: CBH21219.1
gene_biotype: protein_coding
description:
  Putative endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1098
symbol: CBH21220.1
gene_biotype: protein_coding
description:
  Putative iron-sulfur cluster protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1099
symbol: nth
gene_biotype: protein_coding
description:
  DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: CLOST_1101
symbol: cobU
gene_biotype: protein_coding
description:
  Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1102
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: CLOST_1103
symbol: CBH21225.1
gene_biotype: protein_coding
description:
  Putative cobalamin biosynthesis phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1105
symbol: yibK
gene_biotype: protein_coding
description:
  Putative rRNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.


ensembl_gene_id: CLOST_1109
symbol: trxA
gene_biotype: protein_coding
description:
  Thioredoxin (Trx); Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.


ensembl_gene_id: CLOST_1110
symbol: grdE
gene_biotype: protein_coding
description:
  Glycine reductase complex component B subunits alpha and beta; In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination (By similarity).


ensembl_gene_id: CLOST_1112
symbol: grdA
gene_biotype: protein_coding
description:
  Glycine reductase component A selenoprotein; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.


ensembl_gene_id: CLOST_1113
symbol: grdB
gene_biotype: protein_coding
description:
  Glycine reductase component B (47 kDa, subunit gamma); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1115
symbol: grdC
gene_biotype: protein_coding
description:
  Glycine reductase component C subunit beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1116
symbol: grdD
gene_biotype: protein_coding
description:
  Glycine reductase component C subunit alpha; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1120
symbol: CBH21240.1
gene_biotype: protein_coding
description:
  ABC transporter, permease; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_1121
symbol: CBH21241.1
gene_biotype: protein_coding
description:
  Nucleoside transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_1123
symbol: atoD
gene_biotype: protein_coding
description:
  acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: CLOST_1124
symbol: atoA
gene_biotype: protein_coding
description:
  acetyl-CoA:acetoacetyl-CoA transferase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: CLOST_1127
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: CLOST_1129
symbol: infC
gene_biotype: protein_coding
description:
  Protein chain initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: CLOST_1130
symbol: rpmI
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L35; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: CLOST_1131
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: CLOST_1132
symbol: paaF
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase-isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: CLOST_1134
symbol: atoB
gene_biotype: protein_coding
description:
  acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: CLOST_1138
symbol: CBH21258.1
gene_biotype: protein_coding
description:
  Putative Methyl-accepting chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1139
symbol: ktrB
gene_biotype: protein_coding
description:
  Potassium transporter ATPase; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_1141
symbol: CBH21261.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: CLOST_1142
symbol: pheS
gene_biotype: protein_coding
description:
  Phenylalanine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: CLOST_1143
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanine tRNA synthetase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: CLOST_1144
symbol: CBH21264.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: CLOST_1145
symbol: CBH21265.1
gene_biotype: protein_coding
description:
  Putative hydrolase (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1146
symbol: mutS2
gene_biotype: protein_coding
description:
  Recombination and DNA strand exchange inhibitor protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: CLOST_1148
symbol: perR
gene_biotype: protein_coding
description:
  Putative peroxide-responsive repressor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator; Belongs to the Fur family.


ensembl_gene_id: CLOST_1153
symbol: CBH21273.1
gene_biotype: protein_coding
description:
  Putative adenosylcobamide-dependent radical SAM superfamily protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1160
symbol: CBH21280.1
gene_biotype: protein_coding
description:
  Carbon monoxide dehydrogenase 1 (CODH 1); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1161
symbol: CBH21281.1
gene_biotype: protein_coding
description:
  Carbon monoxide dehydrogenase accessory protein (Nickel insertase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1162
symbol: fhs
gene_biotype: protein_coding
description:
  Formate-tetrahydrofolate ligase (Formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: CLOST_1163
symbol: CBH21283.1
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1165
symbol: CBH21285.1
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: CLOST_1167
symbol: CBH21287.1
gene_biotype: protein_coding
description:
  Nickel insertase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1168
symbol: CBH21288.1
gene_biotype: protein_coding
description:
  Corrinoid/iron-sulfur protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1169
symbol: CBH21289.1
gene_biotype: protein_coding
description:
  Corrinoid-iron-sulfur protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1170
symbol: CBH21290.1
gene_biotype: protein_coding
description:
  5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1171
symbol: CBH21291.1
gene_biotype: protein_coding
description:
  Acetyl-CoA synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1176
symbol: CBH21296.1
gene_biotype: protein_coding
description:
  Putative Carbon monoxide dehydrogenase accessory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1179
symbol: CBH21299.1
gene_biotype: protein_coding
description:
  Putative ATP-dependent DNA helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1185
symbol: CBH21305.1
gene_biotype: protein_coding
description:
  Putative Sodium/proton antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1187
symbol: CBH21307.1
gene_biotype: protein_coding
description:
  Putative NADH dehydrogenase (Quinone); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1190
symbol: CBH21310.1
gene_biotype: protein_coding
description:
  Putative nucleotidase CA_C3379; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 5'(3')-deoxyribonucleotidase family.


ensembl_gene_id: CLOST_1192
symbol: gatY
gene_biotype: protein_coding
description:
  D-tagatose 1,6-bisphosphate aldolase 2, catalytic subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1193
symbol: CBH21313.1
gene_biotype: protein_coding
description:
  Putative RNA methylase, NOL1/NOP2/sun family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1194
symbol: CBH21314.1
gene_biotype: protein_coding
description:
  Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: CLOST_1195
symbol: CBH21315.1
gene_biotype: protein_coding
description:
  Uncharacterized RNA methyltransferase CTC_01941; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: CLOST_1200
symbol: CBH21320.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (GntR family) YvoA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1201
symbol: potA
gene_biotype: protein_coding
description:
  Polyamine transporter subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: CLOST_1202
symbol: potB
gene_biotype: protein_coding
description:
  Polyamine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_1206
symbol: frlD
gene_biotype: protein_coding
description:
  Fructoselysine 6-kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1214
symbol: CBH21334.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: CLOST_1216
symbol: ycjV
gene_biotype: protein_coding
description:
  Putative sugar transporter subunit: ATP-binding component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: CLOST_1217
symbol: malP
gene_biotype: protein_coding
description:
  Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: CLOST_1218
symbol: CBH21338.1
gene_biotype: protein_coding
description:
  Putative iron-sulfur protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1221
symbol: CBH21341.1
gene_biotype: protein_coding
description:
  Putative phosphoesterase (PHP domain protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1227
symbol: miaB
gene_biotype: protein_coding
description:
  Isopentenyl-adenosine A37 tRNA methylthiolase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: CLOST_1228
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair recognition factor; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: CLOST_1229
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: CLOST_1230
symbol: miaA
gene_biotype: protein_coding
description:
  Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: CLOST_1231
symbol: hfq
gene_biotype: protein_coding
description:
  Protein hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: CLOST_1232
symbol: CBH21352.1
gene_biotype: protein_coding
description:
  Putative site-specific integrase/recombinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: CLOST_1233
symbol: ynbB
gene_biotype: protein_coding
description:
  Putative C-S lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1235
symbol: lexA
gene_biotype: protein_coding
description:
  LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: CLOST_1237
symbol: CBH21357.1
gene_biotype: protein_coding
description:
  Putative tyrosine recombinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: CLOST_1238
symbol: ADSL
gene_biotype: protein_coding
description:
  Adenylosuccinate lyase (Adenylosuccinase) (ASL) (ASASE); Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: CLOST_1243
symbol: icd
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase, specific for NADP+; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin.


ensembl_gene_id: CLOST_1245
symbol: CBH21365.1
gene_biotype: protein_coding
description:
  Putative site-specific tyrosine recombinase XerC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: CLOST_1248
symbol: CBH21368.1
gene_biotype: protein_coding
description:
  Protein of unknown function; No homology to any previously reported sequences; Belongs to the 'phage' integrase family.


ensembl_gene_id: CLOST_1268
symbol: CBH21388.1
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1283
symbol: CBH21403.1
gene_biotype: protein_coding
description:
  Putative methenyl tetrahydrofolate cyclohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1288
symbol: orr
gene_biotype: protein_coding
description:
  Ornithine racemase; Involved in the ornithine fermentation pathway. Catalyzes the conversion of L-ornithine to D-ornithine. OR could also racemize basic amino acids such as lysine and arginine. Serine, asparagine and alanine could be also converted by OR, but at a lower rate.


ensembl_gene_id: CLOST_1289
symbol: CBH21409.1
gene_biotype: protein_coding
description:
  Putative component of D-ornithine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1290
symbol: oraE
gene_biotype: protein_coding
description:
  D-ornithine aminomutase E component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. OraE may be the catalytic subunit. Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.


ensembl_gene_id: CLOST_1291
symbol: oraS
gene_biotype: protein_coding
description:
  D-ornithine aminomutase S component; Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid. The role of OraS remains obscure; however, it seems to be required for a correct folding of the OraE subunit. The complex is active only on D-ornithine and 2,4- diaminopentanoic acid and not active on L-ornithine, L-beta-lysine, L- alpha-lysine or D-alpha-lysine.


ensembl_gene_id: CLOST_1292
symbol: ortB
gene_biotype: protein_coding
description:
  2-amino-4-ketopentanoate thiolase (AKPT) beta subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP.


ensembl_gene_id: CLOST_1293
symbol: ortA
gene_biotype: protein_coding
description:
  2-amino-4-ketopentanoate thiolase (AKPT), alpha subunit; Involved in the ornithine fermentation pathway. Catalyzes the thiolytic cleavage of 2-amino-4-ketopentanoate (AKP) with coenzyme A (CoA) to form acetyl-CoA and alanine. It is strictly specific for AKP. Belongs to the OrtA family.


ensembl_gene_id: CLOST_1294
symbol: ord
gene_biotype: protein_coding
description:
  (2R,4S)-2,4-diaminopentanoate dehydrogenase (DAPDH); Involved in the ornithine fermentation pathway. Catalyzes the oxidative deamination of (2R,4S)-2,4-diaminopentanoate (DAP) to yield 2-amino-4-ketopentanoate (AKP).


ensembl_gene_id: CLOST_1297
symbol: CBH21417.1
gene_biotype: protein_coding
description:
  Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1300
symbol: aspS-2
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: CLOST_1301
symbol: hisS-2
gene_biotype: protein_coding
description:
  Histidyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1302
symbol: CBH21422.1
gene_biotype: protein_coding
description:
  Putative coproporphyrinogen III oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1304
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: CLOST_1305
symbol: relA
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: CLOST_1306
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: CLOST_1307
symbol: recJ
gene_biotype: protein_coding
description:
  Putative single-stranded-DNA-specific exonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1309
symbol: secF
gene_biotype: protein_coding
description:
  SecYEG protein translocase auxillary subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: CLOST_1310
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecD precursor; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: CLOST_1312
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]


ensembl_gene_id: CLOST_1313
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: CLOST_1316
symbol: ruvB
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase, component of RuvABC resolvasome; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: CLOST_1317
symbol: ruvA
gene_biotype: protein_coding
description:
  Component of RuvABC resolvasome, regulatory subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: CLOST_1318
symbol: ruvC
gene_biotype: protein_coding
description:
  Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: CLOST_1323
symbol: nadE
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: CLOST_1327
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein hflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: CLOST_1330
symbol: CBH21450.1
gene_biotype: protein_coding
description:
  Putative O-methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1331
symbol: mltG
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: CLOST_1332
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1333
symbol: CBH21453.1
gene_biotype: protein_coding
description:
  Putative Tyrosine recombinase xerD-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: CLOST_1334
symbol: nudF
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1337
symbol: CBH21457.1
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1339
symbol: CBH21459.1
gene_biotype: protein_coding
description:
  Putative pyrophosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1340
symbol: recN
gene_biotype: protein_coding
description:
  Factor for double strand breaks DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: CLOST_1342
symbol: CBH21462.1
gene_biotype: protein_coding
description:
  Putative cell adhesion protein (contact hemolysin TlyA-related); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1343
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxyxylulose-5-phosphate synthase, thiamine-requiring, FAD-requiring; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: CLOST_1345
symbol: ispA
gene_biotype: protein_coding
description:
  Geranyltranstransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: CLOST_1346
symbol: xseB
gene_biotype: protein_coding
description:
  Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: CLOST_1347
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: CLOST_1348
symbol: CBH21468.1
gene_biotype: protein_coding
description:
  Putative O-sialoglycoprotein endopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1349
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: CLOST_1351
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: CLOST_1354
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: CLOST_1358
symbol: selA
gene_biotype: protein_coding
description:
  Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: CLOST_1360
symbol: tpx
gene_biotype: protein_coding
description:
  Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: CLOST_1361
symbol: CBH21481.1
gene_biotype: protein_coding
description:
  Putative competence protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1364
symbol: sdaAA
gene_biotype: protein_coding
description:
  L-serine dehydratase (alpha chain); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: CLOST_1366
symbol: rsfS
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: CLOST_1368
symbol: yqeK
gene_biotype: protein_coding
description:
  Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1369
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: CLOST_1370
symbol: yhbY
gene_biotype: protein_coding
description:
  Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: CLOST_1371
symbol: obg
gene_biotype: protein_coding
description:
  GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: CLOST_1372
symbol: rpmA
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: CLOST_1374
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: CLOST_1375
symbol: CBH21495.1
gene_biotype: protein_coding
description:
  Putative Ribonuclease g; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1378
symbol: kamE
gene_biotype: protein_coding
description:
  D-lysine 5,6-aminomutase beta subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively.


ensembl_gene_id: CLOST_1379
symbol: kamD
gene_biotype: protein_coding
description:
  D-lysine 5,6-aminomutase alpha subunit; Catalyzes the migration of the L-beta-lysine and D-lysine epsilon amino group to the delta carbon to produce 3,5-diaminohexanoate and 2,5-diaminohexanoate, respectively.


ensembl_gene_id: CLOST_1383
symbol: kdd
gene_biotype: protein_coding
description:
  3,5-diaminohexanoate dehydrogenase; Involved in the anaerobic fermentation of lysine. Catalyzes the oxidative deamination of L-erythro-3,5-diaminohexanoate (3,5-DAH) to 3-keto-5-aminohexanoate (KAH); Belongs to the KDD family.


ensembl_gene_id: CLOST_1384
symbol: kce
gene_biotype: protein_coding
description:
  3-keto-5-aminohexanoate cleavage enzyme; Involved in the anaerobic fermentation of lysine. Catalyzes the reversible reaction between 3-keto-5-aminohexanoate (KAH) and acetyl-CoA to form 3-aminobutyryl-CoA and acetoacetate. The reaction involves the deprotonation of KAH, the nucleophilic addition onto acetyl-CoA and the intramolecular transfer of the CoA moiety. Belongs to the KCE family.


ensembl_gene_id: CLOST_1385
symbol: kal
gene_biotype: protein_coding
description:
  3-aminobutyryl-CoA ammonia lyase; Involved in the anaerobic fermentation of lysine. Catalyzes the deamination of L-3-aminobutyryl-CoA to produce crotonoyl-CoA. Belongs to the KAL family.


ensembl_gene_id: CLOST_1386
symbol: mgsA
gene_biotype: protein_coding
description:
  Methylglyoxal synthase (MGS); Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.


ensembl_gene_id: CLOST_1388
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: CLOST_1391
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: CLOST_1394
symbol: mreC
gene_biotype: protein_coding
description:
  Putative rod shape-determining protein precursor; Involved in formation and maintenance of cell shape.


ensembl_gene_id: CLOST_1396
symbol: yhdE
gene_biotype: protein_coding
description:
  Putative septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: CLOST_1397
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit precursor; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: CLOST_1398
symbol: rnfA
gene_biotype: protein_coding
description:
  Putative inner membrane subunit of an electron transport system; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: CLOST_1399
symbol: rnfE
gene_biotype: protein_coding
description:
  Putative inner membrane NADH-quinone reductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: CLOST_1400
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex protein precursor; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: CLOST_1401
symbol: rnfD
gene_biotype: protein_coding
description:
  Putative inner membrane oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: CLOST_1402
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: CLOST_1405
symbol: CBH21525.1
gene_biotype: protein_coding
description:
  Putative transglycosylase precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1406
symbol: coaE
gene_biotype: protein_coding
description:
  Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: CLOST_1407
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.


ensembl_gene_id: CLOST_1415
symbol: CBH21535.1
gene_biotype: protein_coding
description:
  ApbE-like lipoprotein precursor; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: CLOST_1418
symbol: CBH21538.1
gene_biotype: protein_coding
description:
  Putative Farnesyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: CLOST_1421
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: CLOST_1422
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxyacid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family.


ensembl_gene_id: CLOST_1424
symbol: CBH21544.1
gene_biotype: protein_coding
description:
  Cation diffusion facilitator family transporter (fragment); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: CLOST_1427
symbol: ssuC-2
gene_biotype: protein_coding
description:
  Alkanesulfonate transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_1429
symbol: CBH21549.1
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1431
symbol: CBH21551.1
gene_biotype: protein_coding
description:
  Putative Ribonuclease III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1432
symbol: rffA
gene_biotype: protein_coding
description:
  TDP-4-oxo-6-deoxy-D-glucose transaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: CLOST_1433
symbol: CBH21553.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: CLOST_1434
symbol: CBH21554.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: CLOST_1439
symbol: fdh
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: CLOST_1444
symbol: thiI
gene_biotype: protein_coding
description:
  Putative thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: CLOST_1445
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1448
symbol: hgdC
gene_biotype: protein_coding
description:
  ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1449
symbol: yjiM
gene_biotype: protein_coding
description:
  Putative 2-hydroxyglutaryl-CoA dehydratase (hgdB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1455
symbol: apeA
gene_biotype: protein_coding
description:
  Putative M18 family aminopeptidase 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1462
symbol: CBH21582.1
gene_biotype: protein_coding
description:
  Rubredoxin (Rd); Rubredoxin is a small nonheme, iron protein lacking acid- labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.


ensembl_gene_id: CLOST_1466
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: CLOST_1467
symbol: CBH21587.1
gene_biotype: protein_coding
description:
  Putative acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1468
symbol: cmk
gene_biotype: protein_coding
description:
  Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1469
symbol: CBH21589.1
gene_biotype: protein_coding
description:
  Putative phosphoglycerate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1471
symbol: korC
gene_biotype: protein_coding
description:
  2-oxoglutarate synthase subunit korC (2-ketoglutarate oxidoreductase gamma chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit gamma).


ensembl_gene_id: CLOST_1472
symbol: korB
gene_biotype: protein_coding
description:
  2-oxoglutarate synthase subunit korB (2-ketoglutarate oxidoreductase beta chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit beta).


ensembl_gene_id: CLOST_1473
symbol: korA
gene_biotype: protein_coding
description:
  2-oxoglutarate synthase subunit korA (2-ketoglutarate oxidoreductase alpha chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit alpha).


ensembl_gene_id: CLOST_1479
symbol: scpB
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: CLOST_1480
symbol: scpA
gene_biotype: protein_coding
description:
  ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: CLOST_1482
symbol: rnjA
gene_biotype: protein_coding
description:
  Ribonuclease J1; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: CLOST_1483
symbol: CBH21603.1
gene_biotype: protein_coding
description:
  Putative membrane-bound metal-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1485
symbol: perR-2
gene_biotype: protein_coding
description:
  Peroxid-Repressor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the Fur family.


ensembl_gene_id: CLOST_1487
symbol: yrrK
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: CLOST_1491
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: CLOST_1493
symbol: iscU
gene_biotype: protein_coding
description:
  Scaffold protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: CLOST_1494
symbol: iscS-2
gene_biotype: protein_coding
description:
  Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: CLOST_1495
symbol: iscR
gene_biotype: protein_coding
description:
  DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_1496
symbol: yrvN
gene_biotype: protein_coding
description:
  Putative helicase associated protein (ATPase, AAA family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1497
symbol: codY
gene_biotype: protein_coding
description:
  GTP-sensing transcriptional pleiotropic repressor codY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.


ensembl_gene_id: CLOST_1498
symbol: topA
gene_biotype: protein_coding
description:
  TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally [...]


ensembl_gene_id: CLOST_1504
symbol: tcpG
gene_biotype: protein_coding
description:
  Putative cell wall associated hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1534
symbol: CBH21654.1
gene_biotype: protein_coding
description:
  Putative sigma factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1542
symbol: CBH21662.1
gene_biotype: protein_coding
description:
  C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: CLOST_1554
symbol: CBH21674.1
gene_biotype: protein_coding
description:
  Putative prophage LambdaCh01, transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1559
symbol: CBH21679.1
gene_biotype: protein_coding
description:
  Putative Phage-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1562
symbol: CBH21682.1
gene_biotype: protein_coding
description:
  Putative phage-related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1568
symbol: CBH21688.1
gene_biotype: protein_coding
description:
  Putative DNA recombinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1574
symbol: rbgA
gene_biotype: protein_coding
description:
  Ribosomal biogenesis GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: CLOST_1575
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: CLOST_1576
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: CLOST_1577
symbol: rimM
gene_biotype: protein_coding
description:
  Putative 16S rRNA-processing protein rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: CLOST_1578
symbol: ylqC
gene_biotype: protein_coding
description:
  Putative RNA binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0109 family.


ensembl_gene_id: CLOST_1579
symbol: rpsP
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S16; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: CLOST_1580
symbol: ffh
gene_biotype: protein_coding
description:
  Signal Recognition Particle (SRP) component with 4.5S RNA (ffs); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: CLOST_1581
symbol: CBH21701.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.


ensembl_gene_id: CLOST_1582
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: CLOST_1583
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome condensation and segregation SMC ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: CLOST_1585
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease 3 (Ribonuclease III) (RNase III); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: CLOST_1587
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor EF-P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: CLOST_1589
symbol: yosS
gene_biotype: protein_coding
description:
  SPbeta phage deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.


ensembl_gene_id: CLOST_1590
symbol: yrbD
gene_biotype: protein_coding
description:
  Sodium/proton-dependent alanine transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_1594
symbol: aroK
gene_biotype: protein_coding
description:
  Putative shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: CLOST_1595
symbol: aroD
gene_biotype: protein_coding
description:
  Putative 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.


ensembl_gene_id: CLOST_1596
symbol: mscL
gene_biotype: protein_coding
description:
  Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: CLOST_1598
symbol: CBH21718.1
gene_biotype: protein_coding
description:
  Conserved membrane protein of unknown function; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.


ensembl_gene_id: CLOST_1601
symbol: CBH21721.1
gene_biotype: protein_coding
description:
  Putative Sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1602
symbol: yedW
gene_biotype: protein_coding
description:
  DNA-binding response regulator in two-component system with YedV; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_1608
symbol: udk
gene_biotype: protein_coding
description:
  Uridine/cytidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1618
symbol: CBH21738.1
gene_biotype: protein_coding
description:
  Putative Membrane spanning protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1620
symbol: kbl
gene_biotype: protein_coding
description:
  Glycine C-acetyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: CLOST_1626
symbol: yyaH
gene_biotype: protein_coding
description:
  Putative Glyoxalase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1643
symbol: CBH21763.1
gene_biotype: protein_coding
description:
  Uncharacterized RNA methyltransferase BCE_0363; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: CLOST_1646
symbol: CBH21766.1
gene_biotype: protein_coding
description:
  Putative aldo/keto reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1647
symbol: pykF
gene_biotype: protein_coding
description:
  Pyruvate kinase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.


ensembl_gene_id: CLOST_1648
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: CLOST_1650
symbol: metQ
gene_biotype: protein_coding
description:
  DL-methionine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: CLOST_1655
symbol: CBH21775.1
gene_biotype: protein_coding
description:
  Putative DNA repair protein (Nucleotide pyrophosphatase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the Nudix hydrolase family.


ensembl_gene_id: CLOST_1656
symbol: CBH21776.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: CLOST_1659
symbol: murB
gene_biotype: protein_coding
description:
  UDP-N-acetylenolpyruvoylglucosamine reductase 2 (UDP-N-acetylmuramate dehydrogenase 2); Cell wall formation.


ensembl_gene_id: CLOST_1660
symbol: CBH21780.1
gene_biotype: protein_coding
description:
  Putative molybdenum cofactor sulfurase (MOSC domain protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1661
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: CLOST_1667
symbol: cbiN
gene_biotype: protein_coding
description:
  Cobalt transport protein cbiN; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.


ensembl_gene_id: CLOST_1668
symbol: cbiM
gene_biotype: protein_coding
description:
  Protein cbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.


ensembl_gene_id: CLOST_1669
symbol: CBH21789.1
gene_biotype: protein_coding
description:
  Periplasmic solute binding protein precursor; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: CLOST_1675
symbol: CBH21795.1
gene_biotype: protein_coding
description:
  Thermonuclease precursor (TNase) (Micrococcal nuclease) (Staphylococcal nuclease) (modular protein).


ensembl_gene_id: CLOST_1678
symbol: rny
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.


ensembl_gene_id: CLOST_1679
symbol: recA
gene_biotype: protein_coding
description:
  DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: CLOST_1680
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: CLOST_1681
symbol: rimO
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: CLOST_1683
symbol: spoIIIE
gene_biotype: protein_coding
description:
  Spore DNA translocase; Function of homologous gene experimentally demonstrated in an other organism; cell process; Belongs to the FtsK/SpoIIIE/SftA family.


ensembl_gene_id: CLOST_1684
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: CLOST_1685
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: CLOST_1687
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: CLOST_1688
symbol: CBH21808.1
gene_biotype: protein_coding
description:
  Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1689
symbol: rbfA
gene_biotype: protein_coding
description:
  30s ribosome binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: CLOST_1690
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: CLOST_1693
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription translation coupling factor involved in Rho-dependent transcription termination; Participates in both transcription termination and antitermination.


ensembl_gene_id: CLOST_1694
symbol: rimP
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: CLOST_1695
symbol: polC
gene_biotype: protein_coding
description:
  DNA polymerase III PolC; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: CLOST_1696
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: CLOST_1697
symbol: CBH21817.1
gene_biotype: protein_coding
description:
  Putative membrane-associated protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1698
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: CLOST_1699
symbol: cdsA
gene_biotype: protein_coding
description:
  CDP-diglyceride synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CDS family.


ensembl_gene_id: CLOST_1700
symbol: ispU
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: CLOST_1702
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: CLOST_1704
symbol: tsf
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: CLOST_1705
symbol: rpsB
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S2; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: CLOST_1709
symbol: sigD
gene_biotype: protein_coding
description:
  RNA polymerase sigma-28 factor (sigma-D); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: CLOST_1711
symbol: cheD
gene_biotype: protein_coding
description:
  CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: CLOST_1713
symbol: cheW
gene_biotype: protein_coding
description:
  Purine-binding chemotaxis protein; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_1714
symbol: cheA
gene_biotype: protein_coding
description:
  Two-component system, chemotaxis family, sensor kinase CheA; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_1715
symbol: cheB
gene_biotype: protein_coding
description:
  Fused chemotaxis regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: CLOST_1717
symbol: ylxH
gene_biotype: protein_coding
description:
  Essential component of the flagellar assembly machinery; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: CLOST_1719
symbol: flhA
gene_biotype: protein_coding
description:
  Putative flagellar export pore protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: CLOST_1720
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar export pore protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: CLOST_1722
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: CLOST_1723
symbol: fliP
gene_biotype: protein_coding
description:
  Component of the flagellar export machinery; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: CLOST_1725
symbol: cheY
gene_biotype: protein_coding
description:
  Regulator of chemotaxis and motility; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_1726
symbol: fliY
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing phosphatase; Function of homologous gene experimentally demonstrated in an other organism; cell process.


ensembl_gene_id: CLOST_1728
symbol: CBH21848.1
gene_biotype: protein_coding
description:
  Putative Flagellar basal body-associated protein FliL precursor; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: CLOST_1733
symbol: flgE
gene_biotype: protein_coding
description:
  Flagellar hook protein; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: CLOST_1737
symbol: CBH21857.1
gene_biotype: protein_coding
description:
  Putative Flagellar export protein FliJ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1738
symbol: fliI
gene_biotype: protein_coding
description:
  Flagellum-specific ATP synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1740
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing component; Function of homologous gene experimentally demonstrated in an other organism; cell process.


ensembl_gene_id: CLOST_1741
symbol: CBH21861.1
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: CLOST_1743
symbol: flgC
gene_biotype: protein_coding
description:
  Flagellar component of cell-proximal portion of basal-body rod; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: CLOST_1744
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: CLOST_1750
symbol: CBH21870.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the methyltransferase superfamily.


ensembl_gene_id: CLOST_1755
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: CLOST_1756
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: CLOST_1757
symbol: CBH21877.1
gene_biotype: protein_coding
description:
  3-deoxy-7-phosphoheptulonate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1758
symbol: folK
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1759
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: CLOST_1760
symbol: folP
gene_biotype: protein_coding
description:
  7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: CLOST_1762
symbol: CBH21882.1
gene_biotype: protein_coding
description:
  Putative Aminodeoxychorismate lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1764
symbol: pabA
gene_biotype: protein_coding
description:
  Aminodeoxychorismate synthase, subunit II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1766
symbol: tktB
gene_biotype: protein_coding
description:
  Transketolase 2, thiamin-binding; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: CLOST_1767
symbol: ppdK
gene_biotype: protein_coding
description:
  Pyruvate, phosphate dikinase (Pyruvate, orthophosphate dikinase); Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: CLOST_1768
symbol: yqfL
gene_biotype: protein_coding
description:
  Positive regulator of gluconeogenesis; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: CLOST_1769
symbol: ccpN
gene_biotype: protein_coding
description:
  Putative transcriptional repressor CcpN; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1770
symbol: glyS
gene_biotype: protein_coding
description:
  Glycine tRNA synthetase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1771
symbol: glyQ
gene_biotype: protein_coding
description:
  Glycine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1773
symbol: recO
gene_biotype: protein_coding
description:
  DNA double strand break repair and homologous recombination factor; Involved in DNA repair and RecF pathway recombination.


ensembl_gene_id: CLOST_1774
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: CLOST_1775
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: CLOST_1777
symbol: yqfG
gene_biotype: protein_coding
description:
  YqfG; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: CLOST_1778
symbol: ybeZ
gene_biotype: protein_coding
description:
  Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1779
symbol: CBH21899.1
gene_biotype: protein_coding
description:
  Putative superoxide reductase (SOR); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1784
symbol: yqeZ
gene_biotype: protein_coding
description:
  Putative membrane bound hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1788
symbol: hinT
gene_biotype: protein_coding
description:
  Purine nucleoside phosphoramidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1790
symbol: CBH21910.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: CLOST_1791
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: CLOST_1792
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...]


ensembl_gene_id: CLOST_1793
symbol: dnaK
gene_biotype: protein_coding
description:
  Chaperone Hsp70, co-chaperone with DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family.


ensembl_gene_id: CLOST_1794
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interacti [...]


ensembl_gene_id: CLOST_1795
symbol: hrcA
gene_biotype: protein_coding
description:
  Transcriptional regulator of heat-shock genes; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: CLOST_1796
symbol: hemN
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: CLOST_1799
symbol: nadC
gene_biotype: protein_coding
description:
  Quinolinate phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.


ensembl_gene_id: CLOST_1800
symbol: nadB
gene_biotype: protein_coding
description:
  Quinolinate synthase, L-aspartate oxidase (B protein) subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1801
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: CLOST_1803
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: CLOST_1806
symbol: CBH21926.1
gene_biotype: protein_coding
description:
  Putative competence membrane protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1813
symbol: CBH21933.1
gene_biotype: protein_coding
description:
  Predicted phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: CLOST_1816
symbol: CBH21936.1
gene_biotype: protein_coding
description:
  Putative pterin-4-alpha-carbinolamine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1821
symbol: CBH21941.1
gene_biotype: protein_coding
description:
  Putative ribonuclease inhibitor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1826
symbol: yvrB
gene_biotype: protein_coding
description:
  Putative iron transport system permease protein YvrB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: CLOST_1827
symbol: yvrC
gene_biotype: protein_coding
description:
  Putative iron transport system substrate-binding protein YvrC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1828
symbol: dapH
gene_biotype: protein_coding
description:
  Tetrahydrodipicolinate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.


ensembl_gene_id: CLOST_1829
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: CLOST_1830
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: CLOST_1837
symbol: tmcAL
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.


ensembl_gene_id: CLOST_1839
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: CLOST_1841
symbol: recG
gene_biotype: protein_coding
description:
  RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: CLOST_1845
symbol: rpmB
gene_biotype: protein_coding
description:
  Ribosomal protein L28; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: CLOST_1847
symbol: rpe
gene_biotype: protein_coding
description:
  D-ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: CLOST_1848
symbol: engC
gene_biotype: protein_coding
description:
  EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: CLOST_1849
symbol: prkC
gene_biotype: protein_coding
description:
  Protein kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1851
symbol: yloN
gene_biotype: protein_coding
description:
  Putative Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: CLOST_1855
symbol: fmt
gene_biotype: protein_coding
description:
  10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: CLOST_1856
symbol: defA
gene_biotype: protein_coding
description:
  DefA; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: CLOST_1857
symbol: priA
gene_biotype: protein_coding
description:
  Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: CLOST_1858
symbol: dfp
gene_biotype: protein_coding
description:
  Fused 4'-phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: CLOST_1859
symbol: rpoZ
gene_biotype: protein_coding
description:
  Omega subunit of RNA polymerase (modular protein); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: CLOST_1863
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: CLOST_1864
symbol: yloA
gene_biotype: protein_coding
description:
  Putative fibronectin binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1865
symbol: yfkH
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein with ribonuclease fold; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF0761 family.


ensembl_gene_id: CLOST_1867
symbol: CBH21987.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: CLOST_1869
symbol: pyrR
gene_biotype: protein_coding
description:
  Transcriptional attenuator and uracil phosphoribosyltransferase activity (minor); Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.


ensembl_gene_id: CLOST_1870
symbol: CBH21990.1
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase, RluD subfamily; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: CLOST_1871
symbol: lspA
gene_biotype: protein_coding
description:
  Prolipoprotein signal peptidase (signal peptidase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: CLOST_1872
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: CLOST_1873
symbol: pfs
gene_biotype: protein_coding
description:
  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: CLOST_1874
symbol: arsC
gene_biotype: protein_coding
description:
  Protein arsC (Arsenate reductase) (Arsenical pump modifier) (Low molecular weight protein-tyrosine-phosphatase).


ensembl_gene_id: CLOST_1876
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucyl-tRNA synthetase 2 (Isoleucine--tRNA ligase 2) (IleRS 2); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 [...]


ensembl_gene_id: CLOST_1880
symbol: ylmF
gene_biotype: protein_coding
description:
  Divisiome protein YlmF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: CLOST_1881
symbol: yggS
gene_biotype: protein_coding
description:
  Putative enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: CLOST_1883
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase [NAD(P)+] (NAD(P)H-dependent glycerol-3-phosphate dehydrogenase); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: CLOST_1884
symbol: yneS
gene_biotype: protein_coding
description:
  YneS; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: CLOST_1885
symbol: der
gene_biotype: protein_coding
description:
  GTPase involved in ribosome synthesis and maintenance; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: CLOST_1888
symbol: phoB
gene_biotype: protein_coding
description:
  DNA-binding response regulator in two-component regulatory system with PhoR (or CreC); Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_1889
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: CLOST_1890
symbol: ftsZ
gene_biotype: protein_coding
description:
  GTP-binding tubulin-like cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: CLOST_1891
symbol: sbp
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: CLOST_1894
symbol: CBH22014.1
gene_biotype: protein_coding
description:
  Putative Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.


ensembl_gene_id: CLOST_1895
symbol: murG
gene_biotype: protein_coding
description:
  N-acetylglucosaminyl transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: CLOST_1896
symbol: ftsW
gene_biotype: protein_coding
description:
  Integral membrane protein involved in stabilizing FstZ ring during cell division; Function of homologous gene experimentally demonstrated in an other organism; cell process; Belongs to the SEDS family.


ensembl_gene_id: CLOST_1897
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: CLOST_1898
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: CLOST_1899
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: CLOST_1900
symbol: ftsI
gene_biotype: protein_coding
description:
  Transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_1902
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-dependent methyltransferase activity on membrane-located substrates; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: CLOST_1903
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase 1; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: CLOST_1906
symbol: ychF
gene_biotype: protein_coding
description:
  Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: CLOST_1910
symbol: CBH22030.1
gene_biotype: protein_coding
description:
  Putative Helicase, UvrD/REP/exonuclease family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1914
symbol: deoC
gene_biotype: protein_coding
description:
  DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: CLOST_1915
symbol: CBH22035.1
gene_biotype: protein_coding
description:
  Putative propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.


ensembl_gene_id: CLOST_1916
symbol: CBH22036.1
gene_biotype: protein_coding
description:
  Putative iron-sulfur flavoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1917
symbol: CBH22037.1
gene_biotype: protein_coding
description:
  Putative regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1920
symbol: CBH22040.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: CLOST_1921
symbol: hisC
gene_biotype: protein_coding
description:
  Putative histidinol-phosphate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1924
symbol: CBH22044.1
gene_biotype: protein_coding
description:
  Putative Sortase (Surface protein transpeptidase), YHCS B.subtilis ortholog; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1926
symbol: CBH22046.1
gene_biotype: protein_coding
description:
  Indolepyruvate ferredoxin oxidoreductase; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.


ensembl_gene_id: CLOST_1927
symbol: CBH22047.1
gene_biotype: protein_coding
description:
  Putative Rubrerythrin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1929
symbol: degS
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Function of homologous gene experimentally demonstrated in an other organism; receptor.


ensembl_gene_id: CLOST_1930
symbol: CBH22050.1
gene_biotype: protein_coding
description:
  Putative CheW protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1932
symbol: CBH22052.1
gene_biotype: protein_coding
description:
  Putative aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1935
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase (tRNA(m7G46)-methyltransferase); Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: CLOST_1937
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridylate synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: CLOST_1938
symbol: nadK
gene_biotype: protein_coding
description:
  NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: CLOST_1948
symbol: sodA
gene_biotype: protein_coding
description:
  Superoxide dismutase, Mn; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: CLOST_1952
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: CLOST_1953
symbol: glpF
gene_biotype: protein_coding
description:
  Glycerol facilitator; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: CLOST_1954
symbol: glpP
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate responding transcription antiterminator; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_1966
symbol: CBH22086.1
gene_biotype: protein_coding
description:
  Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1967
symbol: CBH22087.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1968
symbol: hsdR
gene_biotype: protein_coding
description:
  Putative Type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: CLOST_1972
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase, NAD(P)-binding; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: CLOST_1974
symbol: CBH22094.1
gene_biotype: protein_coding
description:
  Putative Acetyltransferase, GNAT family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_1979
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: CLOST_1980
symbol: ogt
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: CLOST_1982
symbol: clpB-3
gene_biotype: protein_coding
description:
  Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: CLOST_1983
symbol: psuG
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: CLOST_1984
symbol: yeiI
gene_biotype: protein_coding
description:
  Putative kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_1988
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: CLOST_1993
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: CLOST_1997
symbol: zupT-2
gene_biotype: protein_coding
description:
  Zinc transporter zupT; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.


ensembl_gene_id: CLOST_2002
symbol: nadR
gene_biotype: protein_coding
description:
  Putative regulator of de-novo NAD biosythesis NadR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2007
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: CLOST_2008
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamin phosphate synthase (thiamin phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: CLOST_2009
symbol: thiM
gene_biotype: protein_coding
description:
  Hydoxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: CLOST_2010
symbol: thiD
gene_biotype: protein_coding
description:
  Bifunctional hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2018
symbol: CBH22138.1
gene_biotype: protein_coding
description:
  Putative transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2027
symbol: asrC
gene_biotype: protein_coding
description:
  Anaerobic sulfite reductase subunit C; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: CLOST_2030
symbol: ahpC
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2031
symbol: CBH22151.1
gene_biotype: protein_coding
description:
  Putative transcription regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2034
symbol: CBH22154.1
gene_biotype: protein_coding
description:
  Putative Hemerythrin-like protein CA_C0069; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2035
symbol: hutG
gene_biotype: protein_coding
description:
  Formimidoylglutamase (Formiminoglutamase) (Formiminoglutamate hydrolase); Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: CLOST_2043
symbol: leuS
gene_biotype: protein_coding
description:
  leucyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: CLOST_2047
symbol: ymgE
gene_biotype: protein_coding
description:
  Putative inner membrane protein with transglycosylase-associated domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: CLOST_2048
symbol: trpP
gene_biotype: protein_coding
description:
  Putative transmembrane protein involved in tryptophan transport; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2056
symbol: CBH22176.1
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2060
symbol: CBH22180.1
gene_biotype: protein_coding
description:
  Putative HD-GYP domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2065
symbol: CBH22185.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase/phosphodiesterase precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2068
symbol: CBH22188.1
gene_biotype: protein_coding
description:
  Putative CBS:Amino acid-binding ACT; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2071
symbol: CBH22191.1
gene_biotype: protein_coding
description:
  Putative Acetyltransferase (With duplicated domains), possibly RIMI-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2072
symbol: yhfJ
gene_biotype: protein_coding
description:
  Putative Lipoyltransferase and lipoate-protein ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2074
symbol: SurE
gene_biotype: protein_coding
description:
  Predicted acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: CLOST_2078
symbol: CBH22198.1
gene_biotype: protein_coding
description:
  Putative MATE efflux family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2084
symbol: ftsX
gene_biotype: protein_coding
description:
  Cell-division protein; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: CLOST_2087
symbol: yhfJ-2
gene_biotype: protein_coding
description:
  Putative lipoate-protein ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_2088
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: CLOST_2089
symbol: CBH22209.1
gene_biotype: protein_coding
description:
  Putative 5-formyltetrahydrofolate cyclo-ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: CLOST_2093
symbol: CBH22213.1
gene_biotype: protein_coding
description:
  Energy-coupling factor transport system permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2100
symbol: CBH22220.1
gene_biotype: protein_coding
description:
  Putative Polyferredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2106
symbol: CBH22226.1
gene_biotype: protein_coding
description:
  N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.


ensembl_gene_id: CLOST_2109
symbol: CBH22229.1
gene_biotype: protein_coding
description:
  Putative Phosphoglycerol transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2112
symbol: CBH22232.1
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: CLOST_2113
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-acyl carrier protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: CLOST_2116
symbol: atpD
gene_biotype: protein_coding
description:
  F1 sector of membrane-bound ATP synthase, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: CLOST_2117
symbol: atpG
gene_biotype: protein_coding
description:
  F1 sector of membrane-bound ATP synthase, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: CLOST_2118
symbol: atpA
gene_biotype: protein_coding
description:
  F1 sector of membrane-bound ATP synthase, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: CLOST_2119
symbol: atpH
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: CLOST_2120
symbol: atpF
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: CLOST_2121
symbol: atpE
gene_biotype: protein_coding
description:
  AtpE; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: CLOST_2122
symbol: atpB
gene_biotype: protein_coding
description:
  F0 sector of membrane-bound ATP synthase, subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: CLOST_2123
symbol: CBH22243.1
gene_biotype: protein_coding
description:
  Putative ATP synthase protein I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2125
symbol: rffE
gene_biotype: protein_coding
description:
  UDP-N-acetyl glucosamine-2-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: CLOST_2128
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: CLOST_2129
symbol: rpiB
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase B/allose 6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2131
symbol: sua
gene_biotype: protein_coding
description:
  sua5/yciO/yrdC/ywlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: CLOST_2132
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: CLOST_2133
symbol: prmC
gene_biotype: protein_coding
description:
  Methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: CLOST_2137
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: CLOST_2138
symbol: glpX
gene_biotype: protein_coding
description:
  Fructose 1,6-bisphosphatase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2143
symbol: yraL
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: CLOST_2146
symbol: CBH22266.1
gene_biotype: protein_coding
description:
  Putative DNA polymerase III, delta' subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2147
symbol: CBH22267.1
gene_biotype: protein_coding
description:
  Putative thymidylate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2148
symbol: metAA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase (Homoserine O-transsuccinylase) (HTS) (modular protein); Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: CLOST_2161
symbol: rpsI
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S9; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: CLOST_2162
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: CLOST_2163
symbol: truA-2
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A 1 (tRNA-uridine isomerase I 1) (tRNA pseudouridylate synthase I 1); Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: CLOST_2164
symbol: ybaF
gene_biotype: protein_coding
description:
  YbaF; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: CLOST_2166
symbol: cbiO
gene_biotype: protein_coding
description:
  Cobalt import ATP-binding protein cbiO 2; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: CLOST_2167
symbol: ybxA
gene_biotype: protein_coding
description:
  YbxA; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: CLOST_2169
symbol: rplQ
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: CLOST_2170
symbol: rpoA
gene_biotype: protein_coding
description:
  RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: CLOST_2171
symbol: rpsD-2
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: CLOST_2172
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: CLOST_2173
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: CLOST_2174
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: CLOST_2176
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: CLOST_2177
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: CLOST_2178
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase membrane subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: CLOST_2179
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: CLOST_2180
symbol: rpmD
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: CLOST_2181
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: CLOST_2182
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: CLOST_2183
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: CLOST_2184
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: CLOST_2185
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: CLOST_2186
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: CLOST_2187
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: CLOST_2188
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: CLOST_2189
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: CLOST_2190
symbol: rpmC
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L29; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: CLOST_2191
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: CLOST_2192
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: CLOST_2193
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: CLOST_2194
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: CLOST_2195
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: CLOST_2196
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: CLOST_2198
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: CLOST_2199
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: CLOST_2200
symbol: livF
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_2203
symbol: livH
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: CLOST_2206
symbol: tufB
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Tu (duplicate of tufA); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: CLOST_2207
symbol: fusA
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-G, GTP-binding; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase f [...]


ensembl_gene_id: CLOST_2208
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: CLOST_2209
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: CLOST_2210
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: CLOST_2212
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: CLOST_2213
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: CLOST_2214
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: CLOST_2215
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: CLOST_2216
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription termination factor; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: CLOST_2217
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: CLOST_2219
symbol: tufB-2
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Tu (duplicate of tufA); Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: CLOST_2222
symbol: rlmB
gene_biotype: protein_coding
description:
  Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: CLOST_2223
symbol: thyX
gene_biotype: protein_coding
description:
  Thymidylate synthase thyX (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: CLOST_2227
symbol: CBH22347.1
gene_biotype: protein_coding
description:
  Conserved membrane protein of unknown function (PrdG); Homologs of previously reported genes of unknown function.


ensembl_gene_id: CLOST_2228
symbol: prdF
gene_biotype: protein_coding
description:
  Proline racemase A precursor (TcPRACA) (TcPA45-A) (rTcPA45); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the proline racemase family.


ensembl_gene_id: CLOST_2229
symbol: CBH22349.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein (PrdE); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2230
symbol: CBH22350.1
gene_biotype: protein_coding
description:
  Putative uncharacterized protein (PrdD); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2232
symbol: pdrB
gene_biotype: protein_coding
description:
  D-proline reductase gamma chain; D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5-aminovalerate. The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group.


ensembl_gene_id: CLOST_2234
symbol: prdA
gene_biotype: protein_coding
description:
  D-proline reductase proprotein PrdA; D-proline reductase catalyzes the reductive cleavage of a C-N bond in D-proline resulting in the formation of 5-aminovalerate. The alpha subunit has been shown to bind D-proline, presumably via the pyruvoyl group.


ensembl_gene_id: CLOST_2236
symbol: prdC
gene_biotype: protein_coding
description:
  Electron transfer protein; Function of homologous gene experimentally demonstrated in an other organism; putative carrier.


ensembl_gene_id: CLOST_2237
symbol: prdR
gene_biotype: protein_coding
description:
  Sigma-54-dependent transcriptional activator; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_2238
symbol: proX
gene_biotype: protein_coding
description:
  Putative DNA-binding protein (PrdX); Functions in trans to edit the amino acid moiety from incorrectly charged Ala-tRNA(Pro). Has weak activity on correctly charged tRNA(Ala), tRNA(Gly) as well as tRNA(Cys), tRNA(Met), tRNA(Pro), tRNA(Ser) and tRNA(Leu); Belongs to the PRORSD1 family.


ensembl_gene_id: CLOST_2239
symbol: proS
gene_biotype: protein_coding
description:
  Prolyl-tRNA synthetase 2 (Proline--tRNA ligase 2) (ProRS 2); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). Can inadvertently accommodate and process cysteine. Misacylated Cys-tRNA(Pro) is not edited by ProRS; this function may be provided by ProX; Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.


ensembl_gene_id: CLOST_2240
symbol: mrnC
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.


ensembl_gene_id: CLOST_2241
symbol: cysS
gene_biotype: protein_coding
description:
  cysteinyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: CLOST_2242
symbol: CBH22360.1
gene_biotype: protein_coding
description:
  Serine acetyltransferase (SAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2243
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: CLOST_2245
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: CLOST_2246
symbol: ispF
gene_biotype: protein_coding
description:
  2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: CLOST_2247
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: CLOST_2264
symbol: CBH22381.1
gene_biotype: protein_coding
description:
  Putative sensory box-containing diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2265
symbol: cshA
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DEAD box helicase family.


ensembl_gene_id: CLOST_2268
symbol: appC
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (permease); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_2271
symbol: CBH22388.1
gene_biotype: protein_coding
description:
  Putative Cyclopropane-fatty-acyl-phospholipid synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2273
symbol: CBH22390.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: CLOST_2279
symbol: CBH22396.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, permease protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2280
symbol: CBH22397.1
gene_biotype: protein_coding
description:
  Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2287
symbol: CBH22404.1
gene_biotype: protein_coding
description:
  Putative HRDC domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2292
symbol: CBH22409.1
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: CLOST_2293
symbol: gdhA
gene_biotype: protein_coding
description:
  Glutamate dehydrogenase, NADP-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: CLOST_2296
symbol: nuoE
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, chain E; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: CLOST_2297
symbol: rex
gene_biotype: protein_coding
description:
  Redox regulator Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: CLOST_2299
symbol: gcp
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: CLOST_2300
symbol: CBH22417.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: CLOST_2303
symbol: CBH22420.1
gene_biotype: protein_coding
description:
  Conserved membrane protein of unknown function; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.


ensembl_gene_id: CLOST_2305
symbol: CBH22422.1
gene_biotype: protein_coding
description:
  Putative Flagellar protein FliS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2306
symbol: hag
gene_biotype: protein_coding
description:
  Hag; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: CLOST_2311
symbol: prfB
gene_biotype: protein_coding
description:
  PrfB; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: CLOST_2312
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit, ATPase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: CLOST_2313
symbol: hpf
gene_biotype: protein_coding
description:
  Ribosomal subunit interface protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: CLOST_2314
symbol: atpD-2
gene_biotype: protein_coding
description:
  V-type sodium ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: CLOST_2315
symbol: atpB-2
gene_biotype: protein_coding
description:
  V-type ATP synthase beta chain (V-type ATPase subunit B); Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.


ensembl_gene_id: CLOST_2316
symbol: atpA-2
gene_biotype: protein_coding
description:
  V-type ATP synthase alpha chain (V-type ATPase subunit A); Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: CLOST_2319
symbol: CBH22436.1
gene_biotype: protein_coding
description:
  Putative ATPase related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2320
symbol: CBH22437.1
gene_biotype: protein_coding
description:
  Putative V-type sodium ATP synthase subunit I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the V-ATPase 116 kDa subunit family.


ensembl_gene_id: CLOST_2321
symbol: CBH22438.1
gene_biotype: protein_coding
description:
  Putative V-type sodium ATP synthase subunit C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2325
symbol: CBH22442.1
gene_biotype: protein_coding
description:
  Putative GAF sensor signal transduction histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2327
symbol: CBH22444.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator YhcZ; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2332
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar hook-associated capping protein 2 (HAP2); Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: CLOST_2337
symbol: CBH22454.1
gene_biotype: protein_coding
description:
  Homologs of previously reported genes of unknown function; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: CLOST_2338
symbol: CBH22455.1
gene_biotype: protein_coding
description:
  Putative UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2340
symbol: CBH22457.1
gene_biotype: protein_coding
description:
  Putative Acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2344
symbol: CBH22461.1
gene_biotype: protein_coding
description:
  Putative glycosyltransferase (Glycosyl transferase, group 2 family protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2346
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.


ensembl_gene_id: CLOST_2347
symbol: fliW
gene_biotype: protein_coding
description:
  Assembly factor of the flagellum; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.


ensembl_gene_id: CLOST_2352
symbol: flgM
gene_biotype: protein_coding
description:
  Anti-sigma factor repressor of sigma(D)-dependent transcription; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_2353
symbol: yvyF
gene_biotype: protein_coding
description:
  Putative regulator of flagella formation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: CLOST_2355
symbol: recD2
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: CLOST_2356
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase 1; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: CLOST_2358
symbol: CBH22475.1
gene_biotype: protein_coding
description:
  Putative small multi-drug export; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2361
symbol: flgG
gene_biotype: protein_coding
description:
  Flagellar component of cell-distal portion of basal-body rod; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: CLOST_2362
symbol: CBH22479.1
gene_biotype: protein_coding
description:
  Putative Flagellar basal body rod protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: CLOST_2363
symbol: mreB
gene_biotype: protein_coding
description:
  Cell wall structural complex MreBCD, actin-like component MreB; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: CLOST_2364
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: CLOST_2369
symbol: asnS
gene_biotype: protein_coding
description:
  Asparaginyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2372
symbol: CBH22489.1
gene_biotype: protein_coding
description:
  Putative PAC domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2373
symbol: rsiV
gene_biotype: protein_coding
description:
  anti-sigma(V) factor; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_2375
symbol: CBH22492.1
gene_biotype: protein_coding
description:
  Putative sensory box-containing diguanylate cyclase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2376
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: CLOST_2377
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: CLOST_2379
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: CLOST_2383
symbol: CBH22500.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(S); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2388
symbol: CBH22505.1
gene_biotype: protein_coding
description:
  Putative glycosyl transferase precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2391
symbol: pflB
gene_biotype: protein_coding
description:
  Pyruvate formate lyase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2392
symbol: pflA
gene_biotype: protein_coding
description:
  Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: CLOST_2394
symbol: thrC
gene_biotype: protein_coding
description:
  ThrC; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: CLOST_2395
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: CLOST_2396
symbol: CBH22513.1
gene_biotype: protein_coding
description:
  Putative Membrane protein-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2399
symbol: CBH22516.1
gene_biotype: protein_coding
description:
  Putative malate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2406
symbol: CBH22523.1
gene_biotype: protein_coding
description:
  Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_2410
symbol: rbsB
gene_biotype: protein_coding
description:
  D-ribose transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_2413
symbol: rbsD
gene_biotype: protein_coding
description:
  Putative cytoplasmic sugar-binding protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: CLOST_2414
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: CLOST_2415
symbol: rbsR
gene_biotype: protein_coding
description:
  DNA-binding transcriptional repressor of ribose metabolism; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: CLOST_2424
symbol: aspC
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.


ensembl_gene_id: CLOST_2425
symbol: CBH22541.1
gene_biotype: protein_coding
description:
  Putative thiosulfate sulfurtransferase ynjE precursor (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2428
symbol: carA
gene_biotype: protein_coding
description:
  Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family.


ensembl_gene_id: CLOST_2429
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2433
symbol: ygeX
gene_biotype: protein_coding
description:
  2,3-diaminopropionate ammonia-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2438
symbol: fliY-2
gene_biotype: protein_coding
description:
  Cystine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_2446
symbol: CBH22562.1
gene_biotype: protein_coding
description:
  Putative glutathione peroxidase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the glutathione peroxidase family.


ensembl_gene_id: CLOST_2458
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: CLOST_2460
symbol: CBH22575.1
gene_biotype: protein_coding
description:
  Putative Chitin deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: CLOST_2462
symbol: CBH22577.1
gene_biotype: protein_coding
description:
  Iron compound ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: CLOST_2463
symbol: fepD
gene_biotype: protein_coding
description:
  Iron-enterobactin transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: CLOST_2465
symbol: fepC
gene_biotype: protein_coding
description:
  Iron-enterobactin transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: CLOST_2472
symbol: CBH22587.1
gene_biotype: protein_coding
description:
  Putative bacitracin ABC transporter, ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2475
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: CLOST_2483
symbol: CBH22598.1
gene_biotype: protein_coding
description:
  Putative Ribose-phosphate pyrophosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2485
symbol: CBH22600.1
gene_biotype: protein_coding
description:
  Putative NH3-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: CLOST_2488
symbol: CBH22603.1
gene_biotype: protein_coding
description:
  Putative drug resistance ABC-transporter, membrane protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2512
symbol: CBH22627.1
gene_biotype: protein_coding
description:
  Putative pancortin-3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2532
symbol: CBH22647.1
gene_biotype: protein_coding
description:
  Putative Modification methylase PstI (Adenine-specific methyltransferase PstI) (M.PstI); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2533
symbol: rlmH
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: CLOST_2536
symbol: CBH22651.1
gene_biotype: protein_coding
description:
  Putative FMN-binding domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2538
symbol: CBH22653.1
gene_biotype: protein_coding
description:
  Putative MarR-family transcriptional regulator (Transcriptional regulator, MarR family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2548
symbol: lolD
gene_biotype: protein_coding
description:
  Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: CLOST_2549
symbol: CBH22664.1
gene_biotype: protein_coding
description:
  Putative Integral membrane protein (Permease); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2562
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: CLOST_2564
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: CLOST_2566
symbol: yybT
gene_biotype: protein_coding
description:
  Putative phosphoesterase family protein YybT; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.


ensembl_gene_id: CLOST_2569
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: CLOST_2580
symbol: gidB
gene_biotype: protein_coding
description:
  Methyltransferase, SAM-dependent methyltransferase, glucose-inhibited cell-division protein; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: CLOST_2581
symbol: gidA
gene_biotype: protein_coding
description:
  Glucose-inhibited cell-division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: CLOST_2583
symbol: CBH22698.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: CLOST_2585
symbol: trmE
gene_biotype: protein_coding
description:
  GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: CLOST_2587
symbol: oxaAA
gene_biotype: protein_coding
description:
  Sec-independent factor for membrane protein insertion (YidC/SpoIIIJ family); Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: CLOST_2588
symbol: CBH22703.1
gene_biotype: protein_coding
description:
  Conserved protein of unknown function; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: CLOST_2589
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: CLOST_2590
symbol: rpmH
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L34; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL34 family.


