# geneInfo

ensembl_gene_id: MTBPR1_100009
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: MTBPR1_100010
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: MTBPR1_100012
symbol: carA
gene_biotype: protein_coding
description:
  Carbamoyl phosphate synthetase small subunit, glutamine amidotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family.


ensembl_gene_id: MTBPR1_100014
symbol: carB
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.


ensembl_gene_id: MTBPR1_100016
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: MTBPR1_100017
symbol: lrp
gene_biotype: protein_coding
description:
  DNA-binding transcriptional dual regulator, leucine-binding; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MTBPR1_100018
symbol: tsaA
gene_biotype: protein_coding
description:
  Putative peroxiredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100019
symbol: trxB
gene_biotype: protein_coding
description:
  Thioredoxin reductase, FAD/NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_100020
symbol: SCA55379.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulatory protein, LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_100051
symbol: SCA55410.1
gene_biotype: protein_coding
description:
  Hypothetical protein; No homology to any previously reported sequences; Belongs to the 'phage' integrase family.


ensembl_gene_id: MTBPR1_100072
symbol: SCA55431.1
gene_biotype: protein_coding
description:
  Putative Response regulator receiver protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100076
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: MTBPR1_100077
symbol: SCA55436.1
gene_biotype: protein_coding
description:
  Putative ABC-type amino acid transport/signal transduction system, periplasmic component/domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100079
symbol: ydhD
gene_biotype: protein_coding
description:
  Monothiol glutaredoxin; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: MTBPR1_100081
symbol: SCA55440.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the BolA/IbaG family.


ensembl_gene_id: MTBPR1_100083
symbol: ptsN
gene_biotype: protein_coding
description:
  Sugar-specific enzyme IIA component of PTS; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_100084
symbol: hpf
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: MTBPR1_100085
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: MTBPR1_100086
symbol: lptB
gene_biotype: protein_coding
description:
  Putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MTBPR1_100089
symbol: kdsD
gene_biotype: protein_coding
description:
  D-arabinose 5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: MTBPR1_100096
symbol: SCA55455.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_100102
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: MTBPR1_100108
symbol: yedY
gene_biotype: protein_coding
description:
  Exported heme-molybdoenzyme molybdopterin-containing subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospe [...]


ensembl_gene_id: MTBPR1_100109
symbol: yedZ
gene_biotype: protein_coding
description:
  Sulfoxide reductase heme-binding subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...]


ensembl_gene_id: MTBPR1_100114
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: MTBPR1_100116
symbol: metX
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: MTBPR1_100118
symbol: SCA55477.1
gene_biotype: protein_coding
description:
  Putative Periplasmic solute-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100120
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: MTBPR1_100131
symbol: SCA55490.1
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permease protein LivH; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_100132
symbol: SCA55491.1
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system permease protein LivM; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_100133
symbol: livG
gene_biotype: protein_coding
description:
  Leucine/isoleucine/valine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_100138
symbol: paaK
gene_biotype: protein_coding
description:
  phenylacetyl-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: MTBPR1_100139
symbol: pcaF
gene_biotype: protein_coding
description:
  Beta-ketoadipyl CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: MTBPR1_100140
symbol: paaI
gene_biotype: protein_coding
description:
  Phenylacetate pathway hotdog-fold thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_100141
symbol: paaH
gene_biotype: protein_coding
description:
  3-hydroxybutyryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_100142
symbol: paaG
gene_biotype: protein_coding
description:
  acyl-CoA hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_100143
symbol: paaF
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase-isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: MTBPR1_100147
symbol: caiE
gene_biotype: protein_coding
description:
  Putative acyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_100148
symbol: maiA
gene_biotype: protein_coding
description:
  Putative maleylacetoacetate isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10015
symbol: yeaH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0229 family.


ensembl_gene_id: MTBPR1_100150
symbol: SCA55509.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, MarR family (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100158
symbol: SCA55517.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein BruAb1_1365; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100163
symbol: yceI
gene_biotype: protein_coding
description:
  Polyprenyl-pyrophosphate binding protein; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the UPF0312 family.


ensembl_gene_id: MTBPR1_100167
symbol: SCA55526.1
gene_biotype: protein_coding
description:
  Putative Response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100177
symbol: SCA55536.1
gene_biotype: protein_coding
description:
  Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_100184
symbol: SCA55543.1
gene_biotype: protein_coding
description:
  Putative HipA domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100189
symbol: SCA55548.1
gene_biotype: protein_coding
description:
  Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_100191
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme 1; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: MTBPR1_100195
symbol: SCA55554.1
gene_biotype: protein_coding
description:
  Putative sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10023
symbol: cspA
gene_biotype: protein_coding
description:
  Major cold shock protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MTBPR1_10024
symbol: menA
gene_biotype: protein_coding
description:
  1,4-Dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: MTBPR1_10026
symbol: SCA54779.1
gene_biotype: protein_coding
description:
  Putative Response regulator PleD (Includes: Diguanylate cyclase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10035
symbol: SCA54788.1
gene_biotype: protein_coding
description:
  Putative OmpA/MotB protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10036
symbol: yfdZ
gene_biotype: protein_coding
description:
  Putative aminotransferase, PLP-dependent; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_10044
symbol: SCA54797.1
gene_biotype: protein_coding
description:
  Putative HIT family hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10046
symbol: gabD
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase I, NADP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: MTBPR1_10049
symbol: lptD
gene_biotype: protein_coding
description:
  Putative Organic solvent tolerance protein OstA; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.


ensembl_gene_id: MTBPR1_10051
symbol: SCA54804.1
gene_biotype: protein_coding
description:
  Putative hlyB transporter, ATP-binding protein (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10059
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: MTBPR1_10061
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: MTBPR1_10063
symbol: SCA54816.1
gene_biotype: protein_coding
description:
  Putative Response regulator/GGDEF domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10064
symbol: SCA54817.1
gene_biotype: protein_coding
description:
  Putative Adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10071
symbol: SCA54824.1
gene_biotype: protein_coding
description:
  Putative integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: MTBPR1_10087
symbol: sdaA
gene_biotype: protein_coding
description:
  L-serine deaminase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: MTBPR1_10089
symbol: thiI
gene_biotype: protein_coding
description:
  tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: MTBPR1_10090
symbol: yliG
gene_biotype: protein_coding
description:
  Putative AdoMet-dependent methyltransferase, UPF0004 family; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: MTBPR1_10093
symbol: SCA54846.1
gene_biotype: protein_coding
description:
  Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10101
symbol: SCA54854.1
gene_biotype: protein_coding
description:
  Putative Methyl-accepting chemotaxis sensory transducer; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10102
symbol: cheR
gene_biotype: protein_coding
description:
  Chemotaxis regulator, protein-glutamate methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: MTBPR1_10103
symbol: cheD
gene_biotype: protein_coding
description:
  Putative chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: MTBPR1_10104
symbol: cheB
gene_biotype: protein_coding
description:
  Fused chemotaxis regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: MTBPR1_10107
symbol: SCA54860.1
gene_biotype: protein_coding
description:
  Putative CheY-like receiver and GGDEF domain-containing response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10108
symbol: SCA54861.1
gene_biotype: protein_coding
description:
  Putative Methyl-accepting chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10113
symbol: ctaA
gene_biotype: protein_coding
description:
  Heme A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.


ensembl_gene_id: MTBPR1_10117
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase 1; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: MTBPR1_10119
symbol: SCA54872.1
gene_biotype: protein_coding
description:
  Putative SCO1/SenC family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10124
symbol: mnmC
gene_biotype: protein_coding
description:
  tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: MTBPR1_10126
symbol: hisI
gene_biotype: protein_coding
description:
  Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: MTBPR1_10127
symbol: SCA54880.1
gene_biotype: protein_coding
description:
  Putative hydrolase or acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10128
symbol: bioF
gene_biotype: protein_coding
description:
  Putative 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: MTBPR1_10129
symbol: SCA54882.1
gene_biotype: protein_coding
description:
  Putative Hydrolase or acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10130
symbol: bioC
gene_biotype: protein_coding
description:
  Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: MTBPR1_10131
symbol: bioD
gene_biotype: protein_coding
description:
  ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: MTBPR1_10133
symbol: SCA54886.1
gene_biotype: protein_coding
description:
  Putative Response regulator receiver domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10138
symbol: pstC
gene_biotype: protein_coding
description:
  ABC-type phosphate transport system; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: MTBPR1_10140
symbol: pstB
gene_biotype: protein_coding
description:
  High-affinity phosphate transport protein (ABC superfamily, atp_bind); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: MTBPR1_10141
symbol: phoU
gene_biotype: protein_coding
description:
  Phosphate-specific transport system accessory protein PhoU homolog; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: MTBPR1_10142
symbol: phoB
gene_biotype: protein_coding
description:
  DNA-binding response regulator in two-component regulatory system with PhoR (or CreC); Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MTBPR1_10156
symbol: SCA54909.1
gene_biotype: protein_coding
description:
  Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10161
symbol: valS
gene_biotype: protein_coding
description:
  Valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: MTBPR1_10164
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the IlvD/Edd family.


ensembl_gene_id: MTBPR1_10165
symbol: SCA54918.1
gene_biotype: protein_coding
description:
  Putative Extracellular solute-binding protein family 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10168
symbol: SCA54921.1
gene_biotype: protein_coding
description:
  Putative gamma-D-glutamyl-meso-diaminopimelate peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10169
symbol: pcm
gene_biotype: protein_coding
description:
  L-isoaspartate protein carboxylmethyltransferase type II; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: MTBPR1_10170
symbol: surE
gene_biotype: protein_coding
description:
  Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: MTBPR1_10171
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: MTBPR1_10172
symbol: tatC
gene_biotype: protein_coding
description:
  TatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: MTBPR1_10173
symbol: tatB
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: MTBPR1_10174
symbol: tatA
gene_biotype: protein_coding
description:
  TatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: MTBPR1_10175
symbol: SCA54928.1
gene_biotype: protein_coding
description:
  Predicted transcriptional regulator containing the HTH domain; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: MTBPR1_10176
symbol: SCA54929.1
gene_biotype: protein_coding
description:
  Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: MTBPR1_10181
symbol: SCA54934.1
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: MTBPR1_10182
symbol: yadR
gene_biotype: protein_coding
description:
  Putative chaperone involved in Fe-S cluster assembly and activation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the HesB/IscA family.


ensembl_gene_id: MTBPR1_10185
symbol: SCA54938.1
gene_biotype: protein_coding
description:
  Putative ABC-type uncharacterized transport system periplasmic component-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10187
symbol: yajC
gene_biotype: protein_coding
description:
  Immunogenic membrane protein YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: MTBPR1_10188
symbol: secD
gene_biotype: protein_coding
description:
  Protein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: MTBPR1_10189
symbol: secF
gene_biotype: protein_coding
description:
  Protein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: MTBPR1_10191
symbol: sodB
gene_biotype: protein_coding
description:
  Superoxide dismutase, Fe; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: MTBPR1_10193
symbol: SCA54946.1
gene_biotype: protein_coding
description:
  Putative phytoene synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10195
symbol: SCA54948.1
gene_biotype: protein_coding
description:
  Putative phytoene synthase (Terpenoid synthase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10197
symbol: trmFO
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase TrmFO; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: MTBPR1_10198
symbol: SCA54951.1
gene_biotype: protein_coding
description:
  Putative Rhodanese-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10218
symbol: SCA54971.1
gene_biotype: protein_coding
description:
  Putative Hemerythrin family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10221
symbol: metC
gene_biotype: protein_coding
description:
  Putative cystathionine beta-lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10227
symbol: nnrE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...]


ensembl_gene_id: MTBPR1_10228
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: MTBPR1_10230
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: MTBPR1_10231
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: MTBPR1_10232
symbol: lon
gene_biotype: protein_coding
description:
  DNA-binding ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: MTBPR1_10233
symbol: hupB
gene_biotype: protein_coding
description:
  HU, DNA-binding transcriptional regulator, beta subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: MTBPR1_10235
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit A 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: MTBPR1_10236
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit B 2; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: MTBPR1_10237
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: MTBPR1_10238
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: MTBPR1_10240
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: MTBPR1_10241
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: MTBPR1_10242
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, membrane subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: MTBPR1_10243
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: MTBPR1_10244
symbol: nuoJ
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: MTBPR1_10245
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: MTBPR1_10248
symbol: nuoN-2
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: MTBPR1_10250
symbol: coaX
gene_biotype: protein_coding
description:
  Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: MTBPR1_10257
symbol: proS
gene_biotype: protein_coding
description:
  Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.


ensembl_gene_id: MTBPR1_10259
symbol: lolD
gene_biotype: protein_coding
description:
  Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: MTBPR1_10260
symbol: SCA55013.1
gene_biotype: protein_coding
description:
  Putative signal-transduction protein with CBS domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10264
symbol: SCA55017.1
gene_biotype: protein_coding
description:
  Putative Adenylate/guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10265
symbol: dnaE
gene_biotype: protein_coding
description:
  DNA polymerase III alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_10267
symbol: rpsB
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S2; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: MTBPR1_10268
symbol: tsf
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: MTBPR1_10270
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: MTBPR1_10271
symbol: ispU
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: MTBPR1_10273
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: MTBPR1_10274
symbol: SCA55027.1
gene_biotype: protein_coding
description:
  Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_10275
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: MTBPR1_10276
symbol: SCA55029.1
gene_biotype: protein_coding
description:
  Putative Outer membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10277
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: MTBPR1_10278
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: MTBPR1_10279
symbol: lpxA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine acetyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: MTBPR1_10281
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: MTBPR1_10282
symbol: gloA
gene_biotype: protein_coding
description:
  Glyoxalase I, Ni-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_10286
symbol: gltA
gene_biotype: protein_coding
description:
  Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.


ensembl_gene_id: MTBPR1_10287
symbol: gltX
gene_biotype: protein_coding
description:
  Glutamate--tRNA ligase 2; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: MTBPR1_10288
symbol: SCA55041.1
gene_biotype: protein_coding
description:
  Putative Membrane metal-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10289
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: MTBPR1_10290
symbol: SCA55043.1
gene_biotype: protein_coding
description:
  MoeA-like protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: MTBPR1_10291
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: MTBPR1_10293
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: MTBPR1_10294
symbol: pabA
gene_biotype: protein_coding
description:
  Aminodeoxychorismate synthase, subunit II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_10295
symbol: copA
gene_biotype: protein_coding
description:
  Putative copper-importing P-type ATPase A; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10296
symbol: cueR
gene_biotype: protein_coding
description:
  DNA-binding transcriptional activator of copper-responsive regulon genes; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MTBPR1_10297
symbol: SCA55050.1
gene_biotype: protein_coding
description:
  Putative periplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10299
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: MTBPR1_10300
symbol: SCA55053.1
gene_biotype: protein_coding
description:
  Putative Peptidyl-prolyl cis-trans isomerase ppiD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10301
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: MTBPR1_10302
symbol: SCA55055.1
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: MTBPR1_10303
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: MTBPR1_10306
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: MTBPR1_10307
symbol: SCA55060.1
gene_biotype: protein_coding
description:
  Putative Septum formation initiator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10310
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: MTBPR1_10311
symbol: pdhB
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: MTBPR1_10312
symbol: pdhC
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: MTBPR1_10314
symbol: SCA55067.1
gene_biotype: protein_coding
description:
  Putative Arsenite methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10315
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: MTBPR1_10318
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: MTBPR1_10319
symbol: SCA55072.1
gene_biotype: protein_coding
description:
  Putative Peptidase M23B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10321
symbol: SCA55074.1
gene_biotype: protein_coding
description:
  Putative Alpha/beta hydrolase fold protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10325
symbol: dapA
gene_biotype: protein_coding
description:
  4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: MTBPR1_10326
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: MTBPR1_10336
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: MTBPR1_10337
symbol: spoT
gene_biotype: protein_coding
description:
  Bifunctional (p)ppGpp synthetase II and guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: MTBPR1_10339
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: MTBPR1_10340
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-(acyl-carrier-protein) synthase 1; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: MTBPR1_10342
symbol: rnc
gene_biotype: protein_coding
description:
  RNase III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: MTBPR1_10343
symbol: era
gene_biotype: protein_coding
description:
  Membrane-associated, 16S rRNA-binding GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: MTBPR1_10348
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase 4 subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: MTBPR1_10349
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: MTBPR1_10352
symbol: SCA55105.1
gene_biotype: protein_coding
description:
  Conserved exported hypothetical protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: MTBPR1_10353
symbol: ate
gene_biotype: protein_coding
description:
  Putative arginyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: MTBPR1_10356
symbol: SCA55109.1
gene_biotype: protein_coding
description:
  Putative Enoyl-CoA hydratase/isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10357
symbol: SCA55110.1
gene_biotype: protein_coding
description:
  Putative carboxylesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10362
symbol: icmF
gene_biotype: protein_coding
description:
  Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.


ensembl_gene_id: MTBPR1_10366
symbol: ywlF
gene_biotype: protein_coding
description:
  Putative sugar phosphate isomerase YwlF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10367
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: MTBPR1_10368
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional repressor of nrd genes; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: MTBPR1_10369
symbol: ribD
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: MTBPR1_10371
symbol: ribBA
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein RibBA (Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: MTBPR1_10372
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: MTBPR1_10373
symbol: nusB
gene_biotype: protein_coding
description:
  N utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: MTBPR1_10374
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: MTBPR1_10376
symbol: SCA55129.1
gene_biotype: protein_coding
description:
  Putative outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10379
symbol: rpmF
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: MTBPR1_10380
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: MTBPR1_10381
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: MTBPR1_10382
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: MTBPR1_10390
symbol: SCA55143.1
gene_biotype: protein_coding
description:
  Putative ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10394
symbol: SCA55147.1
gene_biotype: protein_coding
description:
  Putative Cytochrome c; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10397
symbol: SCA55150.1
gene_biotype: protein_coding
description:
  Putative cache sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10401
symbol: SCA55154.1
gene_biotype: protein_coding
description:
  Putative ferredoxin oxidoreductase beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10404
symbol: rutE
gene_biotype: protein_coding
description:
  Oxidoreductase subunit of the alternative pyrimidine degradation pathway; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_10407
symbol: SCA55160.1
gene_biotype: protein_coding
description:
  Putative Ferredoxin, 2Fe-2S; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10410
symbol: ispDF
gene_biotype: protein_coding
description:
  Bifunctional enzyme IspD/IspF (Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).


ensembl_gene_id: MTBPR1_10412
symbol: dus
gene_biotype: protein_coding
description:
  Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: MTBPR1_10414
symbol: glnG
gene_biotype: protein_coding
description:
  DNA-binding transcriptional regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: MTBPR1_10420
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: MTBPR1_10421
symbol: hflX
gene_biotype: protein_coding
description:
  Putative GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: MTBPR1_10427
symbol: mazG
gene_biotype: protein_coding
description:
  Nucleoside triphosphate pyrophosphohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_10428
symbol: SCA55181.1
gene_biotype: protein_coding
description:
  Putative Metal-dependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10429
symbol: ycfH
gene_biotype: protein_coding
description:
  Putative metallodependent hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_10430
symbol: metG
gene_biotype: protein_coding
description:
  Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.


ensembl_gene_id: MTBPR1_10432
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: MTBPR1_10434
symbol: rlpA
gene_biotype: protein_coding
description:
  RlpA-like lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: MTBPR1_10437
symbol: thiG
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein, thiazole moiety; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: MTBPR1_10439
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase 2; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: MTBPR1_10440
symbol: accB
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: MTBPR1_10441
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: MTBPR1_10442
symbol: aat
gene_biotype: protein_coding
description:
  Leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: MTBPR1_10448
symbol: nrdJ
gene_biotype: protein_coding
description:
  Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: MTBPR1_10453
symbol: SCA55206.1
gene_biotype: protein_coding
description:
  Putative Predicted acyl-CoA transferase/carnitine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the CoA-transferase III family.


ensembl_gene_id: MTBPR1_10454
symbol: clpA
gene_biotype: protein_coding
description:
  ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family.


ensembl_gene_id: MTBPR1_10455
symbol: clpS
gene_biotype: protein_coding
description:
  Regulatory protein for ClpA substrate specificity; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: MTBPR1_10456
symbol: SCA55209.1
gene_biotype: protein_coding
description:
  Putative Magnetic particle membrane specific GTPase P16; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10466
symbol: SCA55219.1
gene_biotype: protein_coding
description:
  Putative dimethyl sulfoxide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: MTBPR1_10468
symbol: SCA55221.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: MTBPR1_10479
symbol: SCA55232.1
gene_biotype: protein_coding
description:
  Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10480
symbol: SCA55233.1
gene_biotype: protein_coding
description:
  Putative Response regulator consisting of a CheY-like receiver domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10486
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-/propionyl-coenzyme A carboxylase alpha chain (Includes: Biotin carboxylase; Biotin carboxyl carrier protein).


ensembl_gene_id: MTBPR1_10490
symbol: acads
gene_biotype: protein_coding
description:
  Acyl-CoA dehydrogenase, short-chain specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_10493
symbol: SCA55246.1
gene_biotype: protein_coding
description:
  Putative Membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10495
symbol: SCA55248.1
gene_biotype: protein_coding
description:
  Putative Chemotaxis regulator protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10502
symbol: maeB
gene_biotype: protein_coding
description:
  Putative fused malic enzyme oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_10505
symbol: lipB
gene_biotype: protein_coding
description:
  Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: MTBPR1_10507
symbol: SCA55260.1
gene_biotype: protein_coding
description:
  Putative phosphoglycolate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10516
symbol: SCA55269.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: MTBPR1_10517
symbol: crcB
gene_biotype: protein_coding
description:
  Putative fluoride ion transporter CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: MTBPR1_10520
symbol: SCA55273.1
gene_biotype: protein_coding
description:
  Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: MTBPR1_10521
symbol: rplQ
gene_biotype: protein_coding
description:
  50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MTBPR1_10522
symbol: rpoA
gene_biotype: protein_coding
description:
  RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: MTBPR1_10523
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: MTBPR1_10524
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: MTBPR1_10525
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: MTBPR1_10526
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase membrane subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: MTBPR1_10527
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: MTBPR1_10528
symbol: rpmD
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L30; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MTBPR1_10529
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: MTBPR1_10530
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: MTBPR1_10531
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: MTBPR1_10532
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: MTBPR1_10533
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: MTBPR1_10534
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: MTBPR1_10535
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: MTBPR1_10536
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: MTBPR1_10537
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: MTBPR1_10538
symbol: rpmC
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L29; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: MTBPR1_10539
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: MTBPR1_10540
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: MTBPR1_10541
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: MTBPR1_10542
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: MTBPR1_10543
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: MTBPR1_10544
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: MTBPR1_10546
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: MTBPR1_10547
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: MTBPR1_10548
symbol: tufB
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Tu, possible GTP-binding factor (duplicate of tufA); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: MTBPR1_10549
symbol: fusA
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-G, GTP-binding; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase f [...]


ensembl_gene_id: MTBPR1_10550
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: MTBPR1_10551
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: MTBPR1_10555
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' chain (Transcriptase beta' chain) (RNA polymerase beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: MTBPR1_10556
symbol: rpoB
gene_biotype: protein_coding
description:
  RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: MTBPR1_10558
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: MTBPR1_10559
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: MTBPR1_10560
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: MTBPR1_10561
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: MTBPR1_10562
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription termination factor; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: MTBPR1_10563
symbol: secE
gene_biotype: protein_coding
description:
  Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: MTBPR1_10566
symbol: rlmB
gene_biotype: protein_coding
description:
  23S rRNA (guanosine-2'-O-)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: MTBPR1_10578
symbol: SCA55331.1
gene_biotype: protein_coding
description:
  Putative Multi-sensor hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10596
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: MTBPR1_10598
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: MTBPR1_10600
symbol: SCA55353.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, LysR family (ModE-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10603
symbol: SCA55356.1
gene_biotype: protein_coding
description:
  Putative Membrane-fusion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10604
symbol: SCA55357.1
gene_biotype: protein_coding
description:
  Putative Toxin secretion ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_10605
symbol: SCA55358.1
gene_biotype: protein_coding
description:
  Putative hlyB transporter, ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110001
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: MTBPR1_110002
symbol: pth
gene_biotype: protein_coding
description:
  Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: MTBPR1_110004
symbol: ychF
gene_biotype: protein_coding
description:
  Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: MTBPR1_110005
symbol: acnB
gene_biotype: protein_coding
description:
  Bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: MTBPR1_110013
symbol: SCA55574.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_110014
symbol: SCA55575.1
gene_biotype: protein_coding
description:
  Putative branched-chain amino acid ABC transporter, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_110015
symbol: SCA55576.1
gene_biotype: protein_coding
description:
  Putative branched-chain amino acid ABC transporter, periplasmic component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110019
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: MTBPR1_110023
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: MTBPR1_110025
symbol: rnhA
gene_biotype: protein_coding
description:
  Ribonuclease HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: MTBPR1_110027
symbol: SCA55588.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: MTBPR1_110028
symbol: SCA55589.1
gene_biotype: protein_coding
description:
  Putative Beta-lactamase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_110030
symbol: SCA55591.1
gene_biotype: protein_coding
description:
  Putative CHAD domain containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110034
symbol: cobP
gene_biotype: protein_coding
description:
  Bifunctional adenosylcobalamin biosynthesis protein CobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: MTBPR1_110039
symbol: SCA55600.1
gene_biotype: protein_coding
description:
  Putative Nucleotidyl transferase family protein Mannose-1-phosphate guanyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110040
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: MTBPR1_110042
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase 1; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: MTBPR1_110043
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: MTBPR1_110045
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: MTBPR1_110046
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription termination/antitermination L factor; Participates in both transcription termination and antitermination.


ensembl_gene_id: MTBPR1_110048
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: MTBPR1_110049
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: MTBPR1_110050
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: MTBPR1_110051
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: MTBPR1_110052
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: MTBPR1_110054
symbol: yqeF
gene_biotype: protein_coding
description:
  Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: MTBPR1_110063
symbol: prsA
gene_biotype: protein_coding
description:
  Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: MTBPR1_110066
symbol: recR
gene_biotype: protein_coding
description:
  Gap repair protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: MTBPR1_110069
symbol: ybaB
gene_biotype: protein_coding
description:
  DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: MTBPR1_110072
symbol: yhdH
gene_biotype: protein_coding
description:
  Putative oxidoreductase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_110079
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: MTBPR1_110081
symbol: fmt
gene_biotype: protein_coding
description:
  10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: MTBPR1_110082
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: MTBPR1_110083
symbol: SCA55644.1
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: MTBPR1_110086
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: MTBPR1_110087
symbol: ilvI
gene_biotype: protein_coding
description:
  Acetolactate synthase III, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_110088
symbol: ilvH
gene_biotype: protein_coding
description:
  Acetolactate synthase III, thiamin-dependent, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_110089
symbol: ilvC
gene_biotype: protein_coding
description:
  Acetohydroxy acid isomeroreductase and 2-dehydropantoate 2-reductase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: MTBPR1_110092
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: MTBPR1_110093
symbol: mreB
gene_biotype: protein_coding
description:
  Cell wall structural complex MreBCD, actin-like component MreB; Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: MTBPR1_110097
symbol: mrdB
gene_biotype: protein_coding
description:
  Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: MTBPR1_110100
symbol: SCA55661.1
gene_biotype: protein_coding
description:
  Putative TPR repeat protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110101
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: MTBPR1_110102
symbol: SCA55663.1
gene_biotype: protein_coding
description:
  Putative Chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110105
symbol: SCA55666.1
gene_biotype: protein_coding
description:
  Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110106
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: MTBPR1_110109
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: MTBPR1_110110
symbol: rpmA
gene_biotype: protein_coding
description:
  50S ribosomal protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: MTBPR1_110111
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase involved in cell partioning and DNA repair; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: MTBPR1_110112
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamate kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: MTBPR1_110113
symbol: SCA55674.1
gene_biotype: protein_coding
description:
  Putative Protein containing Glycosyl transferase family 2 domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110115
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: MTBPR1_110116
symbol: nadD
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: MTBPR1_110117
symbol: ybeB
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: MTBPR1_110118
symbol: rlmH
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: MTBPR1_110120
symbol: gpmI
gene_biotype: protein_coding
description:
  Phosphoglycero mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: MTBPR1_110124
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: MTBPR1_110126
symbol: SCA55687.1
gene_biotype: protein_coding
description:
  Putative NnrU family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_110128
symbol: gpt
gene_biotype: protein_coding
description:
  Guanine-hypoxanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine.


ensembl_gene_id: MTBPR1_120007
symbol: SCA55701.1
gene_biotype: protein_coding
description:
  Putative Type I secretion membrane fusion protein, HlyD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120008
symbol: SCA55702.1
gene_biotype: protein_coding
description:
  Putative Toxin RTX-I translocation ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120014
symbol: SCA55708.1
gene_biotype: protein_coding
description:
  Putative Methyl-accepting chemotaxis receptor/sensory transducer; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120016
symbol: SCA55710.1
gene_biotype: protein_coding
description:
  Putative TPR repeat-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120020
symbol: SCA55714.1
gene_biotype: protein_coding
description:
  Putative CobQ/CobB/MinD/ParA nucleotide binding domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120021
symbol: SCA55715.1
gene_biotype: protein_coding
description:
  Putative Flp pilus assembly protein CpaD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120022
symbol: SCA55716.1
gene_biotype: protein_coding
description:
  Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the bacterial secretin family.


ensembl_gene_id: MTBPR1_120024
symbol: SCA55718.1
gene_biotype: protein_coding
description:
  Putative Peptidase A24A prepilin type IV; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120025
symbol: SCA55719.1
gene_biotype: protein_coding
description:
  Putative pilin subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120035
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.


ensembl_gene_id: MTBPR1_120038
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, mutase subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: MTBPR1_120039
symbol: purK
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: MTBPR1_120042
symbol: def-2
gene_biotype: protein_coding
description:
  Peptide deformylase 2; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: MTBPR1_120044
symbol: rpsU
gene_biotype: protein_coding
description:
  30S ribosomal protein S21 (modular protein); Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: MTBPR1_120045
symbol: SCA55739.1
gene_biotype: protein_coding
description:
  Putative Hemerythrin-like metal-binding domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120047
symbol: pntB
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: MTBPR1_120048
symbol: pntA
gene_biotype: protein_coding
description:
  Pyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: MTBPR1_120053
symbol: ssb
gene_biotype: protein_coding
description:
  Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: MTBPR1_120054
symbol: SCA55748.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, periplasmic amino acid-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120055
symbol: uvrA
gene_biotype: protein_coding
description:
  ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: MTBPR1_120056
symbol: SCA55750.1
gene_biotype: protein_coding
description:
  Putative DNA polymerase beta domain protein region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120060
symbol: ppnP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: MTBPR1_120061
symbol: rpe
gene_biotype: protein_coding
description:
  D-ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: MTBPR1_120062
symbol: cfxB
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase 2; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: MTBPR1_120063
symbol: tktA
gene_biotype: protein_coding
description:
  Transketolase 1, thiamin-binding; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: MTBPR1_120068
symbol: paaF-2
gene_biotype: protein_coding
description:
  Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120069
symbol: SCA55763.1
gene_biotype: protein_coding
description:
  Putative thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120072
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: MTBPR1_120073
symbol: SCA55767.1
gene_biotype: protein_coding
description:
  Putative malonate transporter, MdcF, AEC family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_120074
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: MTBPR1_120084
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: MTBPR1_120086
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase 4 subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: MTBPR1_120087
symbol: yciA
gene_biotype: protein_coding
description:
  Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_120104
symbol: hcp
gene_biotype: protein_coding
description:
  Hybrid-cluster (4Fe-2S-2O) protein in anaerobic terminal reductases; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.


ensembl_gene_id: MTBPR1_120109
symbol: glnB
gene_biotype: protein_coding
description:
  Regulatory protein P-II for glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.


ensembl_gene_id: MTBPR1_120110
symbol: glnA
gene_biotype: protein_coding
description:
  Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_130004
symbol: SCA55808.1
gene_biotype: protein_coding
description:
  Putative Universal stress protein UspA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_130007
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: MTBPR1_130008
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: MTBPR1_130017
symbol: SCA55821.1
gene_biotype: protein_coding
description:
  Putative Predicted protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_130022
symbol: grpE
gene_biotype: protein_coding
description:
  Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: MTBPR1_130023
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: MTBPR1_130026
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: MTBPR1_130027
symbol: SCA55831.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: MTBPR1_130028
symbol: SCA55832.1
gene_biotype: protein_coding
description:
  Putative transmembrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_130030
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: MTBPR1_130031
symbol: pgi
gene_biotype: protein_coding
description:
  Glucosephosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.


ensembl_gene_id: MTBPR1_130032
symbol: SCA55836.1
gene_biotype: protein_coding
description:
  Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MTBPR1_130033
symbol: SCA55837.1
gene_biotype: protein_coding
description:
  Putative HlyD family secretion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MTBPR1_130036
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: MTBPR1_130037
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: MTBPR1_130040
symbol: SCA55844.1
gene_biotype: protein_coding
description:
  Putative Predicted hydrolase or acyltransferase alpha/beta hydrolase fold protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_130044
symbol: gap
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase 3; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: MTBPR1_130046
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family.


ensembl_gene_id: MTBPR1_130047
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: MTBPR1_130051
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: MTBPR1_130052
symbol: SCA55856.1
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: MTBPR1_130055
symbol: SCA55859.1
gene_biotype: protein_coding
description:
  Putative peptidase, PmbA-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_130056
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UbiD family.


ensembl_gene_id: MTBPR1_130062
symbol: trpS
gene_biotype: protein_coding
description:
  Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: MTBPR1_130064
symbol: murJ
gene_biotype: protein_coding
description:
  Protein MurJ homolog; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: MTBPR1_130065
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: MTBPR1_130067
symbol: ybeY
gene_biotype: protein_coding
description:
  Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: MTBPR1_130068
symbol: ybeZ
gene_biotype: protein_coding
description:
  Putative enzyme with nucleoside triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_130069
symbol: miaB
gene_biotype: protein_coding
description:
  Isopentenyl-adenosine A37 tRNA methylthiolase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: MTBPR1_130075
symbol: SCA55879.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: MTBPR1_130076
symbol: SCA55880.1
gene_biotype: protein_coding
description:
  Putative molecular chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_140006
symbol: SCA55888.1
gene_biotype: protein_coding
description:
  Putative Amino acid abc transporter substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_140021
symbol: SCA55903.1
gene_biotype: protein_coding
description:
  Putative Cytochrome B561; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_140030
symbol: endA
gene_biotype: protein_coding
description:
  DNA-specific endonuclease I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_140037
symbol: umuD
gene_biotype: protein_coding
description:
  DNA polymerase V, subunit D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S24 family.


ensembl_gene_id: MTBPR1_140038
symbol: umuC
gene_biotype: protein_coding
description:
  DNA polymerase V, subunit C; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_140062
symbol: SCA55944.1
gene_biotype: protein_coding
description:
  Putative Type I restriction modification DNA specificity domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_150007
symbol: SCA55960.1
gene_biotype: protein_coding
description:
  Putative Protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase S1B family.


ensembl_gene_id: MTBPR1_150009
symbol: SCA55962.1
gene_biotype: protein_coding
description:
  Putative Group 1 truncated hemoglobin GlbN; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_150020
symbol: SCA55973.1
gene_biotype: protein_coding
description:
  Transporter, CPA2 family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: MTBPR1_150021
symbol: SCA55974.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MTBPR1_150030
symbol: znuB
gene_biotype: protein_coding
description:
  Zinc transporter subunit: membrane component of ABC superfamily; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_150031
symbol: znuC
gene_biotype: protein_coding
description:
  Zinc transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: MTBPR1_150032
symbol: znuA
gene_biotype: protein_coding
description:
  High-affinity zinc uptake system protein ZnuA; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: MTBPR1_150033
symbol: focA
gene_biotype: protein_coding
description:
  Putative formate transporter 1 (Formate channel 1); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_150037
symbol: SCA55990.1
gene_biotype: protein_coding
description:
  Putative Filamentous hemagglutinin family N-terminal domain containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_150039
symbol: SCA55992.1
gene_biotype: protein_coding
description:
  Putative Signal transduction histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_150040
symbol: SCA55993.1
gene_biotype: protein_coding
description:
  Putative Phosphate regulon transcriptional regulatory protein PhoB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_150042
symbol: SCA55995.1
gene_biotype: protein_coding
description:
  Putative Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_150053
symbol: selO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: MTBPR1_160006
symbol: tehB
gene_biotype: protein_coding
description:
  Putative Tellurite resistance protein TehB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_160007
symbol: SCA56016.1
gene_biotype: protein_coding
description:
  Putative Amino acid ABC transporter substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_160008
symbol: SCA56017.1
gene_biotype: protein_coding
description:
  Putative ferredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_160009
symbol: SCA56018.1
gene_biotype: protein_coding
description:
  Putative methyl-accepting chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_160014
symbol: SCA56023.1
gene_biotype: protein_coding
description:
  Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_160022
symbol: dhaS
gene_biotype: protein_coding
description:
  Putative aldehyde dehydrogenase DhaS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_160033
symbol: SCA56042.1
gene_biotype: protein_coding
description:
  Putative Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: MTBPR1_160034
symbol: SCA56043.1
gene_biotype: protein_coding
description:
  Putative MERCURIC REDUCTASE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_160038
symbol: SCA56047.1
gene_biotype: protein_coding
description:
  Putative LytTr DNA-binding domain family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_160041
symbol: SCA56050.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_170004
symbol: clpB
gene_biotype: protein_coding
description:
  Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: MTBPR1_170008
symbol: prmC
gene_biotype: protein_coding
description:
  Release factor glutamine methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: MTBPR1_170009
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: MTBPR1_170010
symbol: hemA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: MTBPR1_170011
symbol: hisS
gene_biotype: protein_coding
description:
  Histidyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_170012
symbol: ispG
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: MTBPR1_170017
symbol: ubiG
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: MTBPR1_170022
symbol: SCA56076.1
gene_biotype: protein_coding
description:
  Putative Zn-dependent protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_170023
symbol: azoR
gene_biotype: protein_coding
description:
  FMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: MTBPR1_170024
symbol: SCA56078.1
gene_biotype: protein_coding
description:
  Putative Ammonium transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_170025
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: MTBPR1_170026
symbol: SCA56080.1
gene_biotype: protein_coding
description:
  Uncharacterized AIPM/Hcit synthase family transferase aq_356; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: MTBPR1_170030
symbol: SCA56084.1
gene_biotype: protein_coding
description:
  Putative Response regulator receiver modulated serine phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_170032
symbol: SCA56086.1
gene_biotype: protein_coding
description:
  Putative NADPH-quinone reductase (Modulator of drug activity B); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_180001
symbol: mamO
gene_biotype: protein_coding
description:
  Trypsin-like serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_180002
symbol: mamM
gene_biotype: protein_coding
description:
  Magnetosome protein MamM; Function of strongly homologous gene; putative membrane component; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MTBPR1_180003
symbol: mamK
gene_biotype: protein_coding
description:
  Magnetosome protein MamK (MreB-actin-like); Function of homologous gene experimentally demonstrated in an other organism; cell process.


ensembl_gene_id: MTBPR1_180004
symbol: SCA56091.1
gene_biotype: protein_coding
description:
  Putative head maturation protease, phage-related; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_180008
symbol: mamH
gene_biotype: protein_coding
description:
  Magnetosome protein MamH (MamH protein, major facilitator superfamily); Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_180010
symbol: mamD-like
gene_biotype: protein_coding
description:
  Putative Magnetosome protein MamD-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.


ensembl_gene_id: MTBPR1_180018
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: MTBPR1_180019
symbol: feoA
gene_biotype: protein_coding
description:
  Fe2+ transport system protein A (modular protein); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_180020
symbol: SCA56107.1
gene_biotype: protein_coding
description:
  Putative Uncharacterized low-complexity protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_180025
symbol: SCA56112.1
gene_biotype: protein_coding
description:
  Putative Hemerythrin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_180027
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor (IHF), DNA-binding protein, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: MTBPR1_180029
symbol: rpsA
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: MTBPR1_180030
symbol: cmk
gene_biotype: protein_coding
description:
  Cytidylate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_180031
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: MTBPR1_190016
symbol: SCA56138.1
gene_biotype: protein_coding
description:
  Putative Two-component hybrid protein, sensory box hisitidine kinase/adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_190021
symbol: SCA56143.1
gene_biotype: protein_coding
description:
  Putative Hemerythrin-like metal-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_190022
symbol: SCA56144.1
gene_biotype: protein_coding
description:
  Putative spermidine/putrescine ABC transporter,(ATP-binding protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MTBPR1_190025
symbol: marA
gene_biotype: protein_coding
description:
  Sodium:alanine symporter; Function of homologous gene experimentally demonstrated in an other organism; putative transporter.


ensembl_gene_id: MTBPR1_190029
symbol: mamM-2
gene_biotype: protein_coding
description:
  Magnetosome protein MamM; Function of homologous gene experimentally demonstrated in an other organism; putative membrane component; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MTBPR1_190030
symbol: SCA56152.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_200003
symbol: SCA56523.1
gene_biotype: protein_coding
description:
  Putative HTH-type transcriptional regulator LrhA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_200006
symbol: SCA56526.1
gene_biotype: protein_coding
description:
  Putative TetR-family transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_200007
symbol: SCA56527.1
gene_biotype: protein_coding
description:
  Putative Major facilitator superfamily protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_200008
symbol: SCA56528.1
gene_biotype: protein_coding
description:
  Putative 2-hydroxychromene-2-carboxylate isomerase (HCCA isomerase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20001
symbol: yusT
gene_biotype: protein_coding
description:
  Uncharacterized HTH-type transcriptional regulator YusT; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_200018
symbol: SCA56538.1
gene_biotype: protein_coding
description:
  Putative DNA-binding helix-turn-helix protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20002
symbol: SCA56154.1
gene_biotype: protein_coding
description:
  Putative enzyme involved in biosynthesis of extracellular polysaccharides; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20003
symbol: SCA56155.1
gene_biotype: protein_coding
description:
  Putative Major facilitator superfamily MFS_1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20004
symbol: SCA56156.1
gene_biotype: protein_coding
description:
  Putative potassium channel protein (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20007
symbol: SCA56159.1
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: MTBPR1_20008
symbol: tas
gene_biotype: protein_coding
description:
  Putative oxidoreductase, NADP(H)-dependent aldo-keto reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_20009
symbol: tesA
gene_biotype: protein_coding
description:
  Multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_20010
symbol: ybbA
gene_biotype: protein_coding
description:
  Putative transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MTBPR1_20012
symbol: SCA56164.1
gene_biotype: protein_coding
description:
  Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the BI1 family.


ensembl_gene_id: MTBPR1_20018
symbol: SCA56170.1
gene_biotype: protein_coding
description:
  Putative Chemotaxis protein CheYIII; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20023
symbol: tsgC
gene_biotype: protein_coding
description:
  Putative glucose ABC transporter permease protein TsgC13; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_20024
symbol: SCA56176.1
gene_biotype: protein_coding
description:
  Putative permease from ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_20026
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: MTBPR1_20027
symbol: SCA56179.1
gene_biotype: protein_coding
description:
  Putative enzyme of heme biosynthesis (HemY-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20028
symbol: SCA56180.1
gene_biotype: protein_coding
description:
  Putative Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: MTBPR1_20029
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: MTBPR1_20030
symbol: tsaD
gene_biotype: protein_coding
description:
  tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: MTBPR1_20032
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: MTBPR1_20035
symbol: SCA56187.1
gene_biotype: protein_coding
description:
  Putative Rieske 2Fe-2S family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20036
symbol: acs-2
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: MTBPR1_20038
symbol: purH
gene_biotype: protein_coding
description:
  Fused IMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_20043
symbol: ybjQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0145 family.


ensembl_gene_id: MTBPR1_20045
symbol: SCA56197.1
gene_biotype: protein_coding
description:
  SUN protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: MTBPR1_20058
symbol: nodQ
gene_biotype: protein_coding
description:
  Bifunctional enzyme NodQ (Includes: Sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: MTBPR1_20059
symbol: cysD
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_20060
symbol: wbpE
gene_biotype: protein_coding
description:
  UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: MTBPR1_20063
symbol: SCA56215.1
gene_biotype: protein_coding
description:
  Putative Glycosyl transferase group 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20069
symbol: hisF
gene_biotype: protein_coding
description:
  Putative imidazole glycerol phosphate synthase subunit hisF2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the HisA/HisF family.


ensembl_gene_id: MTBPR1_20072
symbol: SCA56224.1
gene_biotype: protein_coding
description:
  Putative Asparagine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20097
symbol: SCA56249.1
gene_biotype: protein_coding
description:
  Putative ammonium transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MTBPR1_20107
symbol: SCA56259.1
gene_biotype: protein_coding
description:
  Putative 5-carboxymethyl-2-hydroxymuconate D-isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20109
symbol: hisF-2
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase, catalytic subunit with HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: MTBPR1_20110
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase 2.


ensembl_gene_id: MTBPR1_20111
symbol: hisH-2
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: MTBPR1_20116
symbol: SCA56268.1
gene_biotype: protein_coding
description:
  Putative Glycosyl transferase, group 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20118
symbol: SCA56270.1
gene_biotype: protein_coding
description:
  Putative Iron-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20125
symbol: SCA56277.1
gene_biotype: protein_coding
description:
  Putative membrane protein involved in D-alanine export; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: MTBPR1_20127
symbol: SCA56279.1
gene_biotype: protein_coding
description:
  Putative MaoC domain protein dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20134
symbol: fcl
gene_biotype: protein_coding
description:
  GDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: MTBPR1_20135
symbol: gmd
gene_biotype: protein_coding
description:
  GDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.


ensembl_gene_id: MTBPR1_20136
symbol: cpsB
gene_biotype: protein_coding
description:
  Mannose-1-phosphate guanyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family.


ensembl_gene_id: MTBPR1_20138
symbol: SCA56290.1
gene_biotype: protein_coding
description:
  Putative ABC transporter related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20142
symbol: SCA56294.1
gene_biotype: protein_coding
description:
  Putative UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20143
symbol: SCA56295.1
gene_biotype: protein_coding
description:
  Putative Glycosyl transferase, group 1 family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20154
symbol: hslV
gene_biotype: protein_coding
description:
  Peptidase component of the HslUV protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: MTBPR1_20155
symbol: hslU
gene_biotype: protein_coding
description:
  Molecular chaperone and ATPase component of HslUV protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: MTBPR1_20156
symbol: SCA56308.1
gene_biotype: protein_coding
description:
  Putative Inhibitor of the KinA pathway to sporulation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20159
symbol: SCA56311.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, XRE family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20163
symbol: vapC
gene_biotype: protein_coding
description:
  tRNA(fMet)-specific endonuclease VapC; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: MTBPR1_20169
symbol: bipA
gene_biotype: protein_coding
description:
  GTP-binding protein; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MTBPR1_20173
symbol: SCA56325.1
gene_biotype: protein_coding
description:
  Putative Protein-tyrosine-phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: MTBPR1_20174
symbol: cobB
gene_biotype: protein_coding
description:
  Deacetylase of acetyl-CoA synthetase, NAD-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: MTBPR1_20176
symbol: glnD
gene_biotype: protein_coding
description:
  Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: MTBPR1_20180
symbol: SCA56332.1
gene_biotype: protein_coding
description:
  Putative lytic murein transglycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20184
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: MTBPR1_20187
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: MTBPR1_20188
symbol: coaE
gene_biotype: protein_coding
description:
  Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: MTBPR1_20189
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: MTBPR1_20190
symbol: SCA56342.1
gene_biotype: protein_coding
description:
  Maf-like protein GbCGDNIH1_0004; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: MTBPR1_20191
symbol: SCA56343.1
gene_biotype: protein_coding
description:
  Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: MTBPR1_20192
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: MTBPR1_20193
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: MTBPR1_20196
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: MTBPR1_20200
symbol: SCA56352.1
gene_biotype: protein_coding
description:
  Putative Quercetin 2,3-dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the pirin family.


ensembl_gene_id: MTBPR1_20202
symbol: ogt
gene_biotype: protein_coding
description:
  Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: MTBPR1_20205
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: MTBPR1_20206
symbol: gidA
gene_biotype: protein_coding
description:
  Glucose-inhibited cell-division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: MTBPR1_20207
symbol: rsmG
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: MTBPR1_20211
symbol: SCA56363.1
gene_biotype: protein_coding
description:
  Putative Regulatory protein, LysR:LysR, substrate-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_20217
symbol: SCA56369.1
gene_biotype: protein_coding
description:
  Putative Porin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20219
symbol: SCA56371.1
gene_biotype: protein_coding
description:
  Putative Thiamine monophosphate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20220
symbol: SCA56372.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: MTBPR1_20223
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.  In the N-terminal section; belongs to the DHBP synthase family.


ensembl_gene_id: MTBPR1_20228
symbol: SCA56380.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20230
symbol: hldE
gene_biotype: protein_coding
description:
  Bifunctional protein HldE (Includes: D-beta-D-heptose 7-phosphate kinase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: MTBPR1_20231
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: MTBPR1_20239
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: MTBPR1_20241
symbol: cobO
gene_biotype: protein_coding
description:
  Cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: MTBPR1_20243
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: MTBPR1_20248
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone Hsp40, co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interaction [...]


ensembl_gene_id: MTBPR1_20249
symbol: dnaK
gene_biotype: protein_coding
description:
  Chaperone Hsp70, co-chaperone with DnaJ; Acts as a chaperone; Belongs to the heat shock protein 70 family.


ensembl_gene_id: MTBPR1_20252
symbol: SCA56404.1
gene_biotype: protein_coding
description:
  Putative Hemerythrin HHE cation binding region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20256
symbol: trmL
gene_biotype: protein_coding
description:
  tRNA (cytidine(34)-2'-O)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: MTBPR1_20257
symbol: petA
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: MTBPR1_20258
symbol: petB
gene_biotype: protein_coding
description:
  Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: MTBPR1_20260
symbol: SCA56412.1
gene_biotype: protein_coding
description:
  Putative BLUF domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20263
symbol: rlmN
gene_biotype: protein_coding
description:
  Dual-specificity RNA methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: MTBPR1_20266
symbol: SCA56418.1
gene_biotype: protein_coding
description:
  Putative Flagellar motor protein MotB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20267
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: MTBPR1_20278
symbol: SCA56430.1
gene_biotype: protein_coding
description:
  Putative Periplasmic or secreted lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20279
symbol: SCA56431.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0102 family.


ensembl_gene_id: MTBPR1_20281
symbol: yraL
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: MTBPR1_20284
symbol: SCA56436.1
gene_biotype: protein_coding
description:
  Radical SAM superfamily protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: MTBPR1_20287
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: MTBPR1_20290
symbol: SCA56442.1
gene_biotype: protein_coding
description:
  Putative DMT(Drug/metabolite transporter) superfamily permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20298
symbol: trxA
gene_biotype: protein_coding
description:
  Thioredoxin 1; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thioredoxin family.


ensembl_gene_id: MTBPR1_20304
symbol: tam
gene_biotype: protein_coding
description:
  Trans-aconitate 2-methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.


ensembl_gene_id: MTBPR1_20307
symbol: elbB
gene_biotype: protein_coding
description:
  Isoprenoid biosynthesis protein with amidotransferase-like domain; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme.


ensembl_gene_id: MTBPR1_20309
symbol: fixN
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 1 homolog, bacteroid; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: MTBPR1_20311
symbol: fixP
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome c oxidase subunit FixP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: MTBPR1_20316
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: MTBPR1_20317
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: MTBPR1_20320
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: MTBPR1_20322
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: MTBPR1_20326
symbol: SCA56478.1
gene_biotype: protein_coding
description:
  Putative Response regulator receiver domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_20331
symbol: SCA56483.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA (fragment); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: MTBPR1_20335
symbol: dapB
gene_biotype: protein_coding
description:
  4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: MTBPR1_20336
symbol: nth
gene_biotype: protein_coding
description:
  DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: MTBPR1_20344
symbol: SCA56496.1
gene_biotype: protein_coding
description:
  Cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: MTBPR1_20345
symbol: etfB
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein beta-subunit; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MTBPR1_20346
symbol: etfA
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein alpha-subunit; Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: MTBPR1_20349
symbol: mrp
gene_biotype: protein_coding
description:
  Protein mrp homolog; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: MTBPR1_20353
symbol: htrA
gene_biotype: protein_coding
description:
  Putative periplasmic serine endoprotease DegP-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase S1C family.


ensembl_gene_id: MTBPR1_20354
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: MTBPR1_20355
symbol: yfgD
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_20357
symbol: argH
gene_biotype: protein_coding
description:
  Argininosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_20359
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: MTBPR1_20362
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: MTBPR1_20363
symbol: engB
gene_biotype: protein_coding
description:
  Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: MTBPR1_20364
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: MTBPR1_20365
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: MTBPR1_20366
symbol: rpmH
gene_biotype: protein_coding
description:
  50S ribosomal protein L34; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: MTBPR1_20368
symbol: ycgN
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0260 family.


ensembl_gene_id: MTBPR1_210004
symbol: SCA56552.1
gene_biotype: protein_coding
description:
  Putative amine oxidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_210016
symbol: nhaA
gene_biotype: protein_coding
description:
  Sodium-proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: MTBPR1_250002
symbol: mamZ
gene_biotype: protein_coding
description:
  Magnetosome protein MamZ, major facilitator superfamily; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductas [...]


ensembl_gene_id: MTBPR1_250003
symbol: mamX
gene_biotype: protein_coding
description:
  Magnetosome protein mamX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_250006
symbol: masE
gene_biotype: protein_coding
description:
  Putative Serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_250007
symbol: masD
gene_biotype: protein_coding
description:
  Putative serine/threonine phosphatase 2C; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_260006
symbol: cspE
gene_biotype: protein_coding
description:
  DNA-binding transcriptional repressor; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MTBPR1_260007
symbol: SCA56612.1
gene_biotype: protein_coding
description:
  Putative D-alanine--D-alanine ligase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_270003
symbol: mamS
gene_biotype: protein_coding
description:
  Putative Magnetosome protein MamS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.


ensembl_gene_id: MTBPR1_270004
symbol: mamB
gene_biotype: protein_coding
description:
  Magnetosome protein MamB; Function of strongly homologous gene; cell process; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MTBPR1_30012
symbol: SCA56642.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: MTBPR1_30013
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_30015
symbol: SCA56645.1
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-(acyl-carrier-protein) synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: MTBPR1_30018
symbol: SCA56648.1
gene_biotype: protein_coding
description:
  Putative RND superfamily drug exporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30019
symbol: SCA56649.1
gene_biotype: protein_coding
description:
  Conserved exported hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: MTBPR1_30026
symbol: acpP
gene_biotype: protein_coding
description:
  Acyl carrier protein 2; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: MTBPR1_30029
symbol: SCA56659.1
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-(ACP) synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30039
symbol: SCA56669.1
gene_biotype: protein_coding
description:
  Putative Integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: MTBPR1_30047
symbol: SCA56677.1
gene_biotype: protein_coding
description:
  Putative disulfide formation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the DsbB family.


ensembl_gene_id: MTBPR1_30053
symbol: SCA56683.1
gene_biotype: protein_coding
description:
  Putative cytochrome c-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30057
symbol: SCA56687.1
gene_biotype: protein_coding
description:
  Putative Cytochrome c, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30064
symbol: SCA56694.1
gene_biotype: protein_coding
description:
  Putative cation efflux system protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30065
symbol: cusA
gene_biotype: protein_coding
description:
  Copper/silver efflux system, membrane component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MTBPR1_30066
symbol: SCA56696.1
gene_biotype: protein_coding
description:
  Cobalt/zinc/cadmium efflux RND transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MTBPR1_30086
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: MTBPR1_30096
symbol: SCA56726.1
gene_biotype: protein_coding
description:
  Putative Phage integrase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: MTBPR1_30100
symbol: SCA56730.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the 'phage' integrase family.


ensembl_gene_id: MTBPR1_30101
symbol: SCA56731.1
gene_biotype: protein_coding
description:
  Putative Filamentation induced by cAMP protein Fic; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30114
symbol: SCA56744.1
gene_biotype: protein_coding
description:
  Putative Zn peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30118
symbol: SCA56748.1
gene_biotype: protein_coding
description:
  Putative phage protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30120
symbol: SCA56750.1
gene_biotype: protein_coding
description:
  Putative Ribonuclease G; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30121
symbol: SCA56751.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: MTBPR1_30122
symbol: infA
gene_biotype: protein_coding
description:
  Protein chain initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: MTBPR1_30124
symbol: SCA56754.1
gene_biotype: protein_coding
description:
  Protein tyrosine phosphatase (fragment); Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: MTBPR1_30126
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase and histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: MTBPR1_30127
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: MTBPR1_30128
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: MTBPR1_30133
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit, ATPase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: MTBPR1_30135
symbol: argJ
gene_biotype: protein_coding
description:
  Arginine biosynthesis bifunctional protein ArgJ (Includes: Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: MTBPR1_30139
symbol: SCA56769.1
gene_biotype: protein_coding
description:
  Putative Lysophospholipase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30145
symbol: rpmE
gene_biotype: protein_coding
description:
  50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.


ensembl_gene_id: MTBPR1_30148
symbol: ibpA
gene_biotype: protein_coding
description:
  Heat shock chaperone; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: MTBPR1_30149
symbol: guaC
gene_biotype: protein_coding
description:
  GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.


ensembl_gene_id: MTBPR1_30152
symbol: psuG
gene_biotype: protein_coding
description:
  Pseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: MTBPR1_30154
symbol: hisG-2
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: MTBPR1_30156
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: MTBPR1_30157
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: MTBPR1_30158
symbol: gap-2
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: MTBPR1_30160
symbol: SCA56790.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: MTBPR1_30161
symbol: SCA56791.1
gene_biotype: protein_coding
description:
  Putative 5-formyltetrahydrofolate cyclo-ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: MTBPR1_30165
symbol: ruvC
gene_biotype: protein_coding
description:
  Component of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: MTBPR1_30166
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: MTBPR1_30167
symbol: ruvB
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase, component of RuvABC resolvasome; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: MTBPR1_30168
symbol: ybgC
gene_biotype: protein_coding
description:
  acyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_30169
symbol: tolQ
gene_biotype: protein_coding
description:
  Membrane spanning protein in TolA-TolQ-TolR complex; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: MTBPR1_30172
symbol: tolB
gene_biotype: protein_coding
description:
  Protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: MTBPR1_30173
symbol: omp
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein Omp16 homolog; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: MTBPR1_30174
symbol: cpoB
gene_biotype: protein_coding
description:
  Putative TPR repeat containing exported protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: MTBPR1_30175
symbol: tilS
gene_biotype: protein_coding
description:
  Putative tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: MTBPR1_30176
symbol: ftsH
gene_biotype: protein_coding
description:
  Protease, ATP-dependent zinc-metallo; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: MTBPR1_30178
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: MTBPR1_30180
symbol: moaA
gene_biotype: protein_coding
description:
  Cyclic pyranopterin monophosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: MTBPR1_30181
symbol: ppnK
gene_biotype: protein_coding
description:
  Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: MTBPR1_30185
symbol: SCA56815.1
gene_biotype: protein_coding
description:
  Putative Diguanylate cyclase with PAS/PAC sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30194
symbol: SCA56824.1
gene_biotype: protein_coding
description:
  Putative ABC-type amino acid transport/signal transduction systems, periplasmic component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30196
symbol: SCA56826.1
gene_biotype: protein_coding
description:
  Putative Extracellular solute-binding protein, family 7; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30200
symbol: ttuD
gene_biotype: protein_coding
description:
  Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30205
symbol: modB
gene_biotype: protein_coding
description:
  Molybdenum transport system permease protein ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: MTBPR1_30206
symbol: modC
gene_biotype: protein_coding
description:
  Molybdenum import ATP-binding protein ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: MTBPR1_30207
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: MTBPR1_30209
symbol: SCA56839.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein, family 7; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: MTBPR1_30211
symbol: SCA56841.1
gene_biotype: protein_coding
description:
  Putative C4-dicarboxylate transporter family protein, DctM subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30215
symbol: pyc
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: MTBPR1_30216
symbol: SCA56846.1
gene_biotype: protein_coding
description:
  Putative Methyl-accepting chemotaxis receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30217
symbol: SCA56847.1
gene_biotype: protein_coding
description:
  Putative 4Fe-4S ferredoxin, oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30220
symbol: fdhD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: MTBPR1_30222
symbol: SCA56852.1
gene_biotype: protein_coding
description:
  Putative Allophanate hydrolase, subunit 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30223
symbol: ybgL
gene_biotype: protein_coding
description:
  Putative lactam utilization protein, UPF0271 family; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: MTBPR1_30228
symbol: nasA
gene_biotype: protein_coding
description:
  Nitrate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.


ensembl_gene_id: MTBPR1_30235
symbol: SCA56865.1
gene_biotype: protein_coding
description:
  Putative Trypsin-like serine protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30237
symbol: qseB
gene_biotype: protein_coding
description:
  DNA-binding response regulator in two-component regulatory system with QseC; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MTBPR1_30242
symbol: SCA56872.1
gene_biotype: protein_coding
description:
  Putative Ni,Fe-hydrogenase I cytochrome b subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30251
symbol: SCA56881.1
gene_biotype: protein_coding
description:
  Putative signal transduction protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30255
symbol: glyQ
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase, alpha chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_30260
symbol: yocR
gene_biotype: protein_coding
description:
  Uncharacterized sodium-dependent transporter YocR; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: MTBPR1_30262
symbol: SCA56892.1
gene_biotype: protein_coding
description:
  Putative aminomethyltransferase folate-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the GcvT family.


ensembl_gene_id: MTBPR1_30265
symbol: SCA56895.1
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30276
symbol: SCA56906.1
gene_biotype: protein_coding
description:
  Putative Transcriptional family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30277
symbol: yfcA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component.


ensembl_gene_id: MTBPR1_30279
symbol: guaB
gene_biotype: protein_coding
description:
  IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: MTBPR1_30280
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: MTBPR1_30283
symbol: SCA56913.1
gene_biotype: protein_coding
description:
  Putative sodium symporter protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: MTBPR1_30288
symbol: yjbN
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: MTBPR1_30295
symbol: SCA56925.1
gene_biotype: protein_coding
description:
  Putative Anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: MTBPR1_30298
symbol: SCA56928.1
gene_biotype: protein_coding
description:
  Putative two-component response regulator (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30302
symbol: SCA56932.1
gene_biotype: protein_coding
description:
  Putative Chemotaxis protein CheY; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30305
symbol: SCA56935.1
gene_biotype: protein_coding
description:
  Putative universal stress protein UspA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30306
symbol: SCA56936.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the SOS response-associated peptidase family.


ensembl_gene_id: MTBPR1_30310
symbol: SCA56940.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the LOG family.


ensembl_gene_id: MTBPR1_30314
symbol: SCA56944.1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: MTBPR1_30318
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: MTBPR1_30320
symbol: SCA56950.1
gene_biotype: protein_coding
description:
  Putative C4-dicarboxylate transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30321
symbol: SCA56951.1
gene_biotype: protein_coding
description:
  Putative C4-dicarboxylate transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30330
symbol: SCA56960.1
gene_biotype: protein_coding
description:
  Putative C4-dicarboxylate transport sensor protein DctB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_30335
symbol: gatC
gene_biotype: protein_coding
description:
  Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: MTBPR1_30336
symbol: gatA
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: MTBPR1_30337
symbol: gatB
gene_biotype: protein_coding
description:
  Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: MTBPR1_30339
symbol: yfcG
gene_biotype: protein_coding
description:
  Putative S-transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GST superfamily.


ensembl_gene_id: MTBPR1_30340
symbol: SCA56970.1
gene_biotype: protein_coding
description:
  Putative resolvase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40001
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: MTBPR1_40002
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: MTBPR1_40003
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: MTBPR1_40004
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: MTBPR1_40006
symbol: fadB
gene_biotype: protein_coding
description:
  Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: MTBPR1_40008
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: MTBPR1_40009
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: MTBPR1_40010
symbol: ubiB
gene_biotype: protein_coding
description:
  Putative protein kinase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.


ensembl_gene_id: MTBPR1_40012
symbol: dfp
gene_biotype: protein_coding
description:
  Fused 4'-phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: MTBPR1_40013
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: MTBPR1_40014
symbol: SCA56991.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40015
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_40016
symbol: fumB
gene_biotype: protein_coding
description:
  Anaerobic class I fumarate hydratase (fumarase B); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: MTBPR1_40019
symbol: SCA56996.1
gene_biotype: protein_coding
description:
  Thermostable carboxypeptidase 1; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: MTBPR1_40021
symbol: pip
gene_biotype: protein_coding
description:
  Putative proline iminopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase S33 family.


ensembl_gene_id: MTBPR1_40025
symbol: gap-3
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: MTBPR1_40028
symbol: ybaK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: MTBPR1_40033
symbol: SCA57010.1
gene_biotype: protein_coding
description:
  Putative Uncharacterized membrane protein YrhP; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40041
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: MTBPR1_40047
symbol: SCA57024.1
gene_biotype: protein_coding
description:
  Putative FlgJ-like protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40048
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: MTBPR1_40053
symbol: SCA57030.1
gene_biotype: protein_coding
description:
  Putative Cytochrome c-type biogenesis protein CycH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40056
symbol: ccmF
gene_biotype: protein_coding
description:
  Heme lyase, CcmF subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_40057
symbol: ccmE
gene_biotype: protein_coding
description:
  Periplasmic heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: MTBPR1_40058
symbol: SCA57035.1
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis protein (fragment); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: MTBPR1_40059
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: MTBPR1_40062
symbol: hldD
gene_biotype: protein_coding
description:
  ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: MTBPR1_40065
symbol: SCA57042.1
gene_biotype: protein_coding
description:
  Multi-copper polyphenol oxidoreductase, laccase; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: MTBPR1_40075
symbol: SCA57052.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: MTBPR1_40076
symbol: SCA57053.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: MTBPR1_40085
symbol: fdxA
gene_biotype: protein_coding
description:
  Ferredoxin-2; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: MTBPR1_40089
symbol: SCA57066.1
gene_biotype: protein_coding
description:
  Putative Peptidase M23 domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40090
symbol: SCA57067.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: MTBPR1_40094
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: MTBPR1_40095
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: MTBPR1_40096
symbol: ribF
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase and FAD synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribF family.


ensembl_gene_id: MTBPR1_40099
symbol: serA
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: MTBPR1_40101
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: MTBPR1_40102
symbol: infC
gene_biotype: protein_coding
description:
  Protein chain initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: MTBPR1_40105
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: MTBPR1_40109
symbol: trpB-2
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: MTBPR1_40110
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: MTBPR1_40111
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, beta (carboxyltranferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: MTBPR1_40113
symbol: SCA57090.1
gene_biotype: protein_coding
description:
  Putative FolC bifunctional protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40114
symbol: SCA57091.1
gene_biotype: protein_coding
description:
  Putative Dihydrofolate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_40118
symbol: SCA57095.1
gene_biotype: protein_coding
description:
  Putative ribosomal subunit interface protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40122
symbol: SCA57099.1
gene_biotype: protein_coding
description:
  Putative Heat shock protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40128
symbol: gcvA
gene_biotype: protein_coding
description:
  Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_40137
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperone Hsp60, peptide-dependent ATPase, heat shock protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: MTBPR1_40138
symbol: groES
gene_biotype: protein_coding
description:
  Chaperone Hsp10, affects cell division; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: MTBPR1_40147
symbol: ccmB
gene_biotype: protein_coding
description:
  Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: MTBPR1_40148
symbol: ccmA
gene_biotype: protein_coding
description:
  Cytochrome c biogenesis ATP-binding export protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: MTBPR1_40149
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamin (pyrimidine moiety) biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: MTBPR1_40152
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: MTBPR1_40156
symbol: proC
gene_biotype: protein_coding
description:
  NADP oxidoreductase, coenzyme F420-dependent; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: MTBPR1_40163
symbol: SCA57140.1
gene_biotype: protein_coding
description:
  Putative RNA methyltransferase, TrmH family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40166
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: MTBPR1_40167
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase, FeS subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: MTBPR1_40173
symbol: ada
gene_biotype: protein_coding
description:
  Putative regulatory protein Ada; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40175
symbol: yejB
gene_biotype: protein_coding
description:
  Putative oligopeptide transporter subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MTBPR1_40176
symbol: SCA57153.1
gene_biotype: protein_coding
description:
  Putative oligopeptide transport protein (ABC superfamily, membrane); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: MTBPR1_40177
symbol: yejF
gene_biotype: protein_coding
description:
  Putative fused oligopeptide transporter subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MTBPR1_40180
symbol: gltB
gene_biotype: protein_coding
description:
  Glutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_40181
symbol: gltD
gene_biotype: protein_coding
description:
  Glutamate synthase, 4Fe-4S protein, small subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: MTBPR1_40182
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase 1; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: MTBPR1_40190
symbol: metZ
gene_biotype: protein_coding
description:
  O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: MTBPR1_40191
symbol: tldD
gene_biotype: protein_coding
description:
  Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_40194
symbol: SCA57171.1
gene_biotype: protein_coding
description:
  Gamma-glutamylcysteine synthetase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.


ensembl_gene_id: MTBPR1_40195
symbol: SCA57172.1
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase E; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: MTBPR1_40196
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: MTBPR1_40197
symbol: SCA57174.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulator, XRE family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40204
symbol: ffh
gene_biotype: protein_coding
description:
  Signal Recognition Particle (SRP) component with 4.5S RNA (ffs); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex  [...]


ensembl_gene_id: MTBPR1_40206
symbol: rimM
gene_biotype: protein_coding
description:
  Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: MTBPR1_40207
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: MTBPR1_40208
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: MTBPR1_40210
symbol: SCA57187.1
gene_biotype: protein_coding
description:
  Putative Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40213
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase (isomerase), subunit with LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: MTBPR1_40214
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate isomerase subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: MTBPR1_40215
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: MTBPR1_40217
symbol: SCA57194.1
gene_biotype: protein_coding
description:
  Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MTBPR1_40221
symbol: moaB
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: MTBPR1_40224
symbol: SCA57201.1
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: MTBPR1_40227
symbol: SCA57204.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, MarR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40231
symbol: SCA57208.1
gene_biotype: protein_coding
description:
  Putative Response regulator receiver modulated diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40232
symbol: SCA57209.1
gene_biotype: protein_coding
description:
  Putative response regulator receiver modulated diguanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40234
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoyltranssuccinase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: MTBPR1_40235
symbol: sucA
gene_biotype: protein_coding
description:
  2-oxoglutarate decarboxylase, thiamin-requiring; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_40236
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: MTBPR1_40237
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: MTBPR1_40238
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.


ensembl_gene_id: MTBPR1_40241
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: MTBPR1_40245
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: MTBPR1_40246
symbol: SCA57223.1
gene_biotype: protein_coding
description:
  Putative gamma-glutamyl-gamma-aminobutyrate hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40247
symbol: SCA57224.1
gene_biotype: protein_coding
description:
  Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: MTBPR1_40248
symbol: SCA57225.1
gene_biotype: protein_coding
description:
  Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40250
symbol: SCA57227.1
gene_biotype: protein_coding
description:
  Putative diguanylate phosphodiesterase (EAL domain); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_40256
symbol: SCA57233.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0434 family.


ensembl_gene_id: MTBPR1_40265
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: MTBPR1_40266
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: MTBPR1_50005
symbol: ybiN
gene_biotype: protein_coding
description:
  Putative AdoMet-dependent methyltransferase; Specifically methylates the adenine in position 1618 of 23S rRNA.


ensembl_gene_id: MTBPR1_50006
symbol: SCA57250.1
gene_biotype: protein_coding
description:
  Putative outer membrane basic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50011
symbol: SCA57255.1
gene_biotype: protein_coding
description:
  Putative CheY-like receiver; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50017
symbol: SCA57261.1
gene_biotype: protein_coding
description:
  Putative HDOD domain family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50021
symbol: pheT
gene_biotype: protein_coding
description:
  Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: MTBPR1_50022
symbol: pheS
gene_biotype: protein_coding
description:
  Phenylalanine tRNA synthetase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: MTBPR1_50023
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: MTBPR1_50030
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: MTBPR1_50031
symbol: mtnP
gene_biotype: protein_coding
description:
  S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.


ensembl_gene_id: MTBPR1_50036
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease HII, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: MTBPR1_50037
symbol: SCA57281.1
gene_biotype: protein_coding
description:
  Putative Glycosyl transferase, group 2 family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50041
symbol: napF
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: MTBPR1_50042
symbol: napD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: MTBPR1_50043
symbol: napA
gene_biotype: protein_coding
description:
  Nitrate reductase, periplasmic, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: MTBPR1_50046
symbol: SCA57290.1
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase, electron transfer subunit; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: MTBPR1_50047
symbol: napC
gene_biotype: protein_coding
description:
  Nitrate reductase, cytochrome c-type,periplasmic; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: MTBPR1_50054
symbol: hypE
gene_biotype: protein_coding
description:
  Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_50057
symbol: hypD
gene_biotype: protein_coding
description:
  Protein required for maturation of hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HypD family.


ensembl_gene_id: MTBPR1_50059
symbol: hypF
gene_biotype: protein_coding
description:
  Carbamoyltransferase hypF2; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: MTBPR1_50060
symbol: hypB
gene_biotype: protein_coding
description:
  GTP hydrolase involved in nickel liganding into hydrogenases; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_50061
symbol: hybF
gene_biotype: protein_coding
description:
  Protein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: MTBPR1_50070
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: MTBPR1_50079
symbol: SCA57323.1
gene_biotype: protein_coding
description:
  Exported hypothetical protein; No homology to any previously reported sequences; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.


ensembl_gene_id: MTBPR1_50085
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: MTBPR1_50086
symbol: proV
gene_biotype: protein_coding
description:
  Glycine betaine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_50101
symbol: SCA57345.1
gene_biotype: protein_coding
description:
  Putative RNA methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: MTBPR1_50102
symbol: SCA57346.1
gene_biotype: protein_coding
description:
  Putative ABC-type uncharacterized transport system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50113
symbol: phhB
gene_biotype: protein_coding
description:
  Putative pterin-4-alpha-carbinolamine dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50121
symbol: tag
gene_biotype: protein_coding
description:
  3-methyl-adenine DNA glycosylase I, constitutive; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_50123
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: MTBPR1_50125
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: MTBPR1_50126
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: MTBPR1_50127
symbol: purH-2
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.


ensembl_gene_id: MTBPR1_50131
symbol: SCA57375.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0758 family.


ensembl_gene_id: MTBPR1_50133
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: MTBPR1_50136
symbol: SCA57380.1
gene_biotype: protein_coding
description:
  Putative phosphoribosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50137
symbol: grxC-2
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: MTBPR1_50140
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: MTBPR1_50146
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: MTBPR1_50152
symbol: SCA57396.1
gene_biotype: protein_coding
description:
  Putative Acyl-ACP thioesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50155
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: MTBPR1_50157
symbol: bamD
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: MTBPR1_50159
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: MTBPR1_50160
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: MTBPR1_50161
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: MTBPR1_50162
symbol: ftsQ
gene_biotype: protein_coding
description:
  Putative Cell division protein FtsQ; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: MTBPR1_50166
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: MTBPR1_50168
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: MTBPR1_50169
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: MTBPR1_50170
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: MTBPR1_50171
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: MTBPR1_50174
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-dependent methyltransferase activity on membrane-located substrates; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: MTBPR1_50178
symbol: SCA57422.1
gene_biotype: protein_coding
description:
  Putative hydrolase or acyltransferase of alpha/beta superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50181
symbol: yafC
gene_biotype: protein_coding
description:
  Uncharacterized HTH-type transcriptional regulator YafC; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_50184
symbol: coq7
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein COQ7; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: MTBPR1_50189
symbol: ycbL
gene_biotype: protein_coding
description:
  Putative metal-binding hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_50193
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: MTBPR1_50197
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: MTBPR1_50199
symbol: queG
gene_biotype: protein_coding
description:
  Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: MTBPR1_50201
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: MTBPR1_50202
symbol: dhfrIII
gene_biotype: protein_coding
description:
  Dihydrofolate reductase type 3; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: MTBPR1_50210
symbol: SCA57454.1
gene_biotype: protein_coding
description:
  Putative tetraheme cytochrome-c type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50217
symbol: SCA57461.1
gene_biotype: protein_coding
description:
  Putative 5'-Nucleotidase/apyrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: MTBPR1_50218
symbol: SCA57462.1
gene_biotype: protein_coding
description:
  Putative sulfite oxidase molybdopterin subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50222
symbol: SCA57466.1
gene_biotype: protein_coding
description:
  Putative thioredoxin-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50224
symbol: SCA57468.1
gene_biotype: protein_coding
description:
  Putative cytochrome c assembly protein, transmembrane domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_50231
symbol: nqrF
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: MTBPR1_50232
symbol: rsxA
gene_biotype: protein_coding
description:
  Putative inner membrane subunit of an electron transport system; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: MTBPR1_50233
symbol: nqrD
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: MTBPR1_50234
symbol: nqrC
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: MTBPR1_50235
symbol: nqrB
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: MTBPR1_50236
symbol: nqrA
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: MTBPR1_50238
symbol: apbE
gene_biotype: protein_coding
description:
  Thiamine biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: MTBPR1_50239
symbol: putA
gene_biotype: protein_coding
description:
  Bifunctional protein PutA (Includes: Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: MTBPR1_50240
symbol: SCA57484.1
gene_biotype: protein_coding
description:
  Putative AraC family transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60008
symbol: SCA57495.1
gene_biotype: protein_coding
description:
  Putative ABC transporter subunit (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_60009
symbol: SCA57496.1
gene_biotype: protein_coding
description:
  Hypothetical protein; No homology to any previously reported sequences; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: MTBPR1_60035
symbol: SCA57522.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the CoA-transferase III family.


ensembl_gene_id: MTBPR1_60040
symbol: SCA57527.1
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MTBPR1_60042
symbol: rpmJ
gene_biotype: protein_coding
description:
  Putative ribosome maturation protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: MTBPR1_60043
symbol: SCA57530.1
gene_biotype: protein_coding
description:
  Putative Proline dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60045
symbol: SCA57532.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0335 family.


ensembl_gene_id: MTBPR1_60047
symbol: SCA57534.1
gene_biotype: protein_coding
description:
  Putative two-component response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60048
symbol: SCA57535.1
gene_biotype: protein_coding
description:
  Carboxylate-amine ligase Rru_A2462; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: MTBPR1_60052
symbol: SCA57539.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MTBPR1_60053
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: MTBPR1_60055
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: MTBPR1_60057
symbol: SCA57544.1
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein RF_0080; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60058
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: MTBPR1_60059
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: MTBPR1_60063
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: MTBPR1_60067
symbol: fabD
gene_biotype: protein_coding
description:
  malonyl-CoA-(acyl-carrier-protein) transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_60068
symbol: fabG-2
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MTBPR1_60070
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: MTBPR1_60071
symbol: mltG
gene_biotype: protein_coding
description:
  Conserved exported hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: MTBPR1_60076
symbol: SCA57563.1
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase/reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: MTBPR1_60083
symbol: SCA57570.1
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: MTBPR1_60086
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: MTBPR1_60087
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: MTBPR1_60088
symbol: plsY
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: MTBPR1_60090
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: MTBPR1_60091
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: MTBPR1_60093
symbol: rpmG
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L33; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: MTBPR1_60096
symbol: SCA57583.1
gene_biotype: protein_coding
description:
  Putative diguanylate phosphodiesterase (EAL domain) with Response Regulator Receiver modulation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60103
symbol: SCA57590.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60113
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: MTBPR1_60115
symbol: ywlC
gene_biotype: protein_coding
description:
  Threonylcarbamoyl-AMP synthase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: MTBPR1_60116
symbol: SCA57603.1
gene_biotype: protein_coding
description:
  Putative Protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60118
symbol: SCA57605.1
gene_biotype: protein_coding
description:
  Putative lipid carrier protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60122
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: MTBPR1_60127
symbol: pepA
gene_biotype: protein_coding
description:
  Putative cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: MTBPR1_60130
symbol: SCA57617.1
gene_biotype: protein_coding
description:
  Putative Anti-sigma-factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60136
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: MTBPR1_60140
symbol: SCA57627.1
gene_biotype: protein_coding
description:
  Putative phosphate permease jhp_1384; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60141
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: MTBPR1_60142
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_60146
symbol: SCA57633.1
gene_biotype: protein_coding
description:
  Putative phosphatidylglycerophosphate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60147
symbol: SCA57634.1
gene_biotype: protein_coding
description:
  Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60150
symbol: aspS
gene_biotype: protein_coding
description:
  Aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: MTBPR1_60158
symbol: SCA57645.1
gene_biotype: protein_coding
description:
  Putative Thermophilic serine proteinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the peptidase S8 family.


ensembl_gene_id: MTBPR1_60160
symbol: SCA57647.1
gene_biotype: protein_coding
description:
  Putative Cobalamin (Vitamin B12) biosynthesis CbiX protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60163
symbol: SCA57650.1
gene_biotype: protein_coding
description:
  Putative transcriptional activator protein fnrA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60164
symbol: SCA57651.1
gene_biotype: protein_coding
description:
  cAMP-binding proteins-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: MTBPR1_60165
symbol: rsmA
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: MTBPR1_60166
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: MTBPR1_60167
symbol: SCA57654.1
gene_biotype: protein_coding
description:
  Putative Parvulin-like peptidyl-prolyl isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60173
symbol: SCA57660.1
gene_biotype: protein_coding
description:
  Putative Acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60177
symbol: hemN
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen-III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: MTBPR1_60178
symbol: SCA57665.1
gene_biotype: protein_coding
description:
  Putative amino acid ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60179
symbol: ppi
gene_biotype: protein_coding
description:
  Putative peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: MTBPR1_60184
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: MTBPR1_60186
symbol: mak
gene_biotype: protein_coding
description:
  Manno(fructo)kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_60189
symbol: SCA57676.1
gene_biotype: protein_coding
description:
  Putative sarcosine-dimethylglycine methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60190
symbol: ygaV
gene_biotype: protein_coding
description:
  Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: MTBPR1_60191
symbol: SCA57678.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: MTBPR1_60192
symbol: SCA57679.1
gene_biotype: protein_coding
description:
  Acriflavin resistance protein D; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MTBPR1_60193
symbol: SCA57680.1
gene_biotype: protein_coding
description:
  Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MTBPR1_60195
symbol: xseB
gene_biotype: protein_coding
description:
  Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: MTBPR1_60196
symbol: ispA
gene_biotype: protein_coding
description:
  Geranyltranstransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: MTBPR1_60197
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxyxylulose-5-phosphate synthase, thiamine-requiring, FAD-requiring; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: MTBPR1_60198
symbol: yqxC
gene_biotype: protein_coding
description:
  Putative rRNA methyltransferase YqxC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60201
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: MTBPR1_60202
symbol: fabI-2
gene_biotype: protein_coding
description:
  Enoyl-(acyl-carrier-protein) reductase, NADH-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_60205
symbol: SCA57692.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0178 family.


ensembl_gene_id: MTBPR1_60206
symbol: SCA57693.1
gene_biotype: protein_coding
description:
  Putative PDZ/DHR/GLGF domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60209
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: MTBPR1_60210
symbol: fieF
gene_biotype: protein_coding
description:
  Cation-efflux pump FieF; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: MTBPR1_60213
symbol: SCA57700.1
gene_biotype: protein_coding
description:
  Putative membrane fusion protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MTBPR1_60214
symbol: SCA57701.1
gene_biotype: protein_coding
description:
  Cobalt-zinc-cadmium resistance protein CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: MTBPR1_60223
symbol: SCA57710.1
gene_biotype: protein_coding
description:
  Putative RND family efflux transporter MFP subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: MTBPR1_60224
symbol: SCA57711.1
gene_biotype: protein_coding
description:
  Putative acetyltransferases BadL (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60225
symbol: badM
gene_biotype: protein_coding
description:
  Putative HTH-type transcriptional regulator BadM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_60231
symbol: SCA57718.1
gene_biotype: protein_coding
description:
  Putative PAS protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70001
symbol: SCA57729.1
gene_biotype: protein_coding
description:
  Putative Outer membrane adhesin like proteiin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70002
symbol: SCA57730.1
gene_biotype: protein_coding
description:
  Putative serine/threonine-protein kinase pknL; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70009
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinulease of nucleotide excision repair, DNA damage recognition component; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. I [...]


ensembl_gene_id: MTBPR1_70011
symbol: SCA57739.1
gene_biotype: protein_coding
description:
  Putative threonine efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70013
symbol: SCA57741.1
gene_biotype: protein_coding
description:
  Putative Glycerophosphoryl diester phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70015
symbol: rlmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase J; Specifically methylates the adenine in position 2030 of 23S rRNA.


ensembl_gene_id: MTBPR1_70018
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: MTBPR1_70019
symbol: atpD
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: MTBPR1_70020
symbol: atpG-2
gene_biotype: protein_coding
description:
  ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: MTBPR1_70021
symbol: atpA
gene_biotype: protein_coding
description:
  F1 sector of membrane-bound ATP synthase, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: MTBPR1_70022
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: MTBPR1_70023
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: MTBPR1_70024
symbol: tal
gene_biotype: protein_coding
description:
  Putative transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: MTBPR1_70025
symbol: SCA57753.1
gene_biotype: protein_coding
description:
  Putative Site-specific tyrosine recombinase XerC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70026
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: MTBPR1_70031
symbol: yjjK
gene_biotype: protein_coding
description:
  Fused putative transporter subunits of ABC superfamily: ATP-binding components; Function of strongly homologous gene; putative transporter.


ensembl_gene_id: MTBPR1_70037
symbol: SCA57765.1
gene_biotype: protein_coding
description:
  Putative Methyltransferase-16; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70040
symbol: rluA
gene_biotype: protein_coding
description:
  Pseudouridine synthase for 23S rRNA (position 746) and tRNAphe(position 32); Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: MTBPR1_70041
symbol: SCA57769.1
gene_biotype: protein_coding
description:
  Putative Toluene tolerance transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70044
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: MTBPR1_70047
symbol: metH
gene_biotype: protein_coding
description:
  Putative Response regulator receiver protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme;fragment of methionine synthase (B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF) (part 2).


ensembl_gene_id: MTBPR1_70053
symbol: uvrD
gene_biotype: protein_coding
description:
  Putative DNA helicase II homolog; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70056
symbol: nadE
gene_biotype: protein_coding
description:
  Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: MTBPR1_70057
symbol: gltX-2
gene_biotype: protein_coding
description:
  Glutamate--tRNA ligase 1; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: MTBPR1_70058
symbol: cysS
gene_biotype: protein_coding
description:
  cysteinyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: MTBPR1_70061
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: MTBPR1_70069
symbol: hisP
gene_biotype: protein_coding
description:
  Histidine/lysine/arginine/ornithine transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_70070
symbol: SCA57798.1
gene_biotype: protein_coding
description:
  Putative periplasmic binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: MTBPR1_70073
symbol: SCA57801.1
gene_biotype: protein_coding
description:
  Putative amino acid ABC transporter, periplasmic amino acid-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70081
symbol: SCA57809.1
gene_biotype: protein_coding
description:
  Putative effector of murein hydrolase LrgA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70082
symbol: oxyR
gene_biotype: protein_coding
description:
  Putative hydrogen peroxide-inducible genes activator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: MTBPR1_70088
symbol: cheB-2
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase 1; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: MTBPR1_70097
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: MTBPR1_70100
symbol: SCA57828.1
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: MTBPR1_70102
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: MTBPR1_70103
symbol: SCA57831.1
gene_biotype: protein_coding
description:
  Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: MTBPR1_70106
symbol: SCA57834.1
gene_biotype: protein_coding
description:
  Basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: MTBPR1_70111
symbol: SCA57839.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex,dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: MTBPR1_70115
symbol: SCA57843.1
gene_biotype: protein_coding
description:
  Putative transketolase N-terminal section; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70116
symbol: SCA57844.1
gene_biotype: protein_coding
description:
  Putative transketolase C-terminal section; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70118
symbol: SCA57846.1
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-(acyl-carrier-protein) reductase FabG; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70119
symbol: SCA57847.1
gene_biotype: protein_coding
description:
  Putative GDP-L-fucose synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_70122
symbol: SCA57850.1
gene_biotype: protein_coding
description:
  Putative GDP-L-fucose synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70127
symbol: SCA57855.1
gene_biotype: protein_coding
description:
  Putative D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70131
symbol: SCA57859.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: MTBPR1_70144
symbol: SCA57872.1
gene_biotype: protein_coding
description:
  Putative NUDIX hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70145
symbol: SCA57873.1
gene_biotype: protein_coding
description:
  Putative Phase-1 flagellin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70146
symbol: SCA57874.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: MTBPR1_70149
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar basal body P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: MTBPR1_70152
symbol: dksA
gene_biotype: protein_coding
description:
  RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: MTBPR1_70154
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: MTBPR1_70156
symbol: flgG
gene_biotype: protein_coding
description:
  Flagellar component of cell-distal portion of basal-body rod; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: MTBPR1_70158
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar FliL protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: MTBPR1_70159
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: MTBPR1_70162
symbol: cheY-4
gene_biotype: protein_coding
description:
  Chemotaxis regulator transmitting signal to flagellar motor component; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MTBPR1_70164
symbol: SCA57892.1
gene_biotype: protein_coding
description:
  Putative PPE-repeat protein (Cell mobility); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70167
symbol: speH
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.


ensembl_gene_id: MTBPR1_70168
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: MTBPR1_70169
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: MTBPR1_70173
symbol: SCA57901.1
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: MTBPR1_70176
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: MTBPR1_70178
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: MTBPR1_70182
symbol: recA
gene_biotype: protein_coding
description:
  DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: MTBPR1_70183
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: MTBPR1_70191
symbol: der
gene_biotype: protein_coding
description:
  GTPase involved in ribosome synthesis and maintenance; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: MTBPR1_70195
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: MTBPR1_70197
symbol: accA-2
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: MTBPR1_70198
symbol: ybaR
gene_biotype: protein_coding
description:
  Putative sulfate transporter YbaR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_70201
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: MTBPR1_70205
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: MTBPR1_70218
symbol: emrE
gene_biotype: protein_coding
description:
  Multidrug resistance protein; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin.


ensembl_gene_id: MTBPR1_80003
symbol: SCA57949.1
gene_biotype: protein_coding
description:
  Putative Glucosyl-3-phosphoglycerate/mannosyl-3-phosphoglycerate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80005
symbol: SCA57951.1
gene_biotype: protein_coding
description:
  Putative glucosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80016
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: MTBPR1_80017
symbol: epd
gene_biotype: protein_coding
description:
  D-erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: MTBPR1_80019
symbol: pqqB
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.


ensembl_gene_id: MTBPR1_80020
symbol: pqqC
gene_biotype: protein_coding
description:
  Pyrroloquinoline-quinone synthase; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.


ensembl_gene_id: MTBPR1_80022
symbol: pqqE
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).


ensembl_gene_id: MTBPR1_80027
symbol: SCA57973.1
gene_biotype: protein_coding
description:
  Putative ABC transporter (Substrate-binding protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80028
symbol: SCA57974.1
gene_biotype: protein_coding
description:
  Putative ABC transporter protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80039
symbol: SCA57985.1
gene_biotype: protein_coding
description:
  Amino acid ABC transporter ATP-binding protein, PAAT family; Belongs to the ABC transporter superfamily.


ensembl_gene_id: MTBPR1_80045
symbol: SCA57991.1
gene_biotype: protein_coding
description:
  Putative amino acid-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80049
symbol: SCA57995.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80066
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: MTBPR1_80068
symbol: nadC
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide pyrophosphorylase (carboxylating); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the NadC/ModD family.


ensembl_gene_id: MTBPR1_80071
symbol: SCA58017.1
gene_biotype: protein_coding
description:
  Putative ABC transporter, substrate-binding protein, family 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80072
symbol: ltaE
gene_biotype: protein_coding
description:
  Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.


ensembl_gene_id: MTBPR1_80073
symbol: SCA58019.1
gene_biotype: protein_coding
description:
  Putative Mov34/MPN/PAD-1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80075
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: MTBPR1_80076
symbol: rpoH-3
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: MTBPR1_80079
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: MTBPR1_80080
symbol: hisZ
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.


ensembl_gene_id: MTBPR1_80085
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: MTBPR1_80086
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: MTBPR1_80096
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: MTBPR1_80105
symbol: SCA58051.1
gene_biotype: protein_coding
description:
  Putative aspartate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80107
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: MTBPR1_80110
symbol: mrcA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1A (Includes: Penicillin-insensitive transglycosylase; Penicillin-sensitive transpeptidase).


ensembl_gene_id: MTBPR1_80111
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: MTBPR1_80114
symbol: SCA58060.1
gene_biotype: protein_coding
description:
  Putative two-component transcriptional response regulator (CheY family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80115
symbol: bcp
gene_biotype: protein_coding
description:
  Putative peroxiredoxin bcp; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80116
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: MTBPR1_80118
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: MTBPR1_80120
symbol: anmK
gene_biotype: protein_coding
description:
  Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: MTBPR1_80125
symbol: iscS-2
gene_biotype: protein_coding
description:
  Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: MTBPR1_80126
symbol: iscU
gene_biotype: protein_coding
description:
  Iron-binding protein believed to be involved in Fe-S protein formation or repair; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: MTBPR1_80127
symbol: iscA
gene_biotype: protein_coding
description:
  FeS cluster assembly protein; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the HesB/IscA family.


ensembl_gene_id: MTBPR1_80128
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone protein HscB homolog; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: MTBPR1_80129
symbol: hscA
gene_biotype: protein_coding
description:
  DnaK-like molecular chaperone specific for IscU; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: MTBPR1_80130
symbol: fdx
gene_biotype: protein_coding
description:
  (2Fe-2S) ferredoxin; Function of homologous gene experimentally demonstrated in an other organism; carrier.


ensembl_gene_id: MTBPR1_80131
symbol: SCA58077.1
gene_biotype: protein_coding
description:
  Putative protein believed to be involved in assembly of Fe-S clusters; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: MTBPR1_80133
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: MTBPR1_80141
symbol: SCA58087.1
gene_biotype: protein_coding
description:
  Putative integrase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80144
symbol: SCA58090.1
gene_biotype: protein_coding
description:
  Exported hypothetical protein; No homology to any previously reported sequences; Belongs to the bacterial secretin family.


ensembl_gene_id: MTBPR1_80155
symbol: SCA58101.1
gene_biotype: protein_coding
description:
  Putative Transglycosylase, SLT domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80158
symbol: SCA58104.1
gene_biotype: protein_coding
description:
  Putative Integrase/recombinase xerD homolog; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family.


ensembl_gene_id: MTBPR1_80173
symbol: SCA58119.1
gene_biotype: protein_coding
description:
  Putative TmRNA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80177
symbol: SCA58123.1
gene_biotype: protein_coding
description:
  Putative ParA protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_80205
symbol: ymfC
gene_biotype: protein_coding
description:
  23S rRNA pseudouridine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: MTBPR1_90003
symbol: yffB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the ArsC family.


ensembl_gene_id: MTBPR1_90006
symbol: queF
gene_biotype: protein_coding
description:
  NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: MTBPR1_90007
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]


ensembl_gene_id: MTBPR1_90008
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: MTBPR1_90015
symbol: SCA58168.1
gene_biotype: protein_coding
description:
  Putative branched-chain-amino-acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90019
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein FolD 1 (Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: MTBPR1_90020
symbol: SCA58173.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0235 family.


ensembl_gene_id: MTBPR1_90026
symbol: yliK
gene_biotype: protein_coding
description:
  methylmalonyl-CoA mutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_90027
symbol: argK
gene_biotype: protein_coding
description:
  Membrane ATPase/protein kinase; Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_90030
symbol: SCA58183.1
gene_biotype: protein_coding
description:
  Putative tRNA/rRNA cytosine-C5-methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: MTBPR1_90037
symbol: yhiN
gene_biotype: protein_coding
description:
  Putative oxidoreductase with FAD/NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: MTBPR1_90044
symbol: gcdH
gene_biotype: protein_coding
description:
  glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_90046
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: MTBPR1_90048
symbol: ompR-5
gene_biotype: protein_coding
description:
  DNA-binding response regulator in two-component regulatory system with EnvZ; Function of homologous gene experimentally demonstrated in an other organism; regulator.


ensembl_gene_id: MTBPR1_90049
symbol: SCA58202.1
gene_biotype: protein_coding
description:
  Putative two-component sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90052
symbol: cbiD
gene_biotype: protein_coding
description:
  Putative cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: MTBPR1_90054
symbol: SCA58207.1
gene_biotype: protein_coding
description:
  Putative membrane copper tolerance protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90056
symbol: cobB-2
gene_biotype: protein_coding
description:
  Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: MTBPR1_90062
symbol: SCA58215.1
gene_biotype: protein_coding
description:
  Putative ATPase (MoxR-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90068
symbol: SCA58221.1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0246 family.


ensembl_gene_id: MTBPR1_90070
symbol: pck
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.


ensembl_gene_id: MTBPR1_90071
symbol: SCA58224.1
gene_biotype: protein_coding
description:
  Putative heme iron utilization protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90077
symbol: npr
gene_biotype: protein_coding
description:
  Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: MTBPR1_90078
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: MTBPR1_90080
symbol: SCA58233.1
gene_biotype: protein_coding
description:
  Putative Glycosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90083
symbol: ahcY
gene_biotype: protein_coding
description:
  Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: MTBPR1_90085
symbol: SCA58238.1
gene_biotype: protein_coding
description:
  Putative histidine kinase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90092
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease UvrABC, endonuclease subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: MTBPR1_90094
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: MTBPR1_90096
symbol: SCA58249.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: MTBPR1_90098
symbol: moaE
gene_biotype: protein_coding
description:
  Molybdopterin synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: MTBPR1_90099
symbol: SCA58252.1
gene_biotype: protein_coding
description:
  Putative lysine decarboxylase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90100
symbol: SCA58253.1
gene_biotype: protein_coding
description:
  cAMP-binding protein-catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase.


ensembl_gene_id: MTBPR1_90101
symbol: SCA58254.1
gene_biotype: protein_coding
description:
  Putative flavoprotein oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90122
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: MTBPR1_90125
symbol: queC
gene_biotype: protein_coding
description:
  7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: MTBPR1_90127
symbol: queE
gene_biotype: protein_coding
description:
  7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: MTBPR1_90131
symbol: cbbZ
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: MTBPR1_90134
symbol: glmU
gene_biotype: protein_coding
description:
  Fused N-acetyl glucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: MTBPR1_90135
symbol: glmS
gene_biotype: protein_coding
description:
  L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: MTBPR1_90136
symbol: SCA58289.1
gene_biotype: protein_coding
description:
  Putative Protein YciI; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90148
symbol: SCA58301.1
gene_biotype: protein_coding
description:
  Putative chemotaxis sensory transducer; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.


ensembl_gene_id: MTBPR1_90149
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: MTBPR1_90150
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: MTBPR1_90151
symbol: purS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...]


ensembl_gene_id: MTBPR1_90157
symbol: SCA58310.1
gene_biotype: protein_coding
description:
  Putative cation transport protein chaC-related; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: MTBPR1_90163
symbol: SCA58316.1
gene_biotype: protein_coding
description:
  Trk system potassium uptake protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: MTBPR1_90166
symbol: SCA58319.1
gene_biotype: protein_coding
description:
  Putative Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: MTBPR1_90167
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: MTBPR1_90168
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: MTBPR1_90169
symbol: SCA58322.1
gene_biotype: protein_coding
description:
  Transporter; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: MTBPR1_90170
symbol: SCA58323.1
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: MTBPR1_90171
symbol: SCA58324.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


