# geneInfo

ensembl_gene_id: c4043
symbol: yrdC
gene_biotype: protein_coding
description:
  Protein yrdC; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: c4044
symbol: yrdD
gene_biotype: protein_coding
description:
  Hypothetical protein yrdD; Escherichia coli K-12 ortholog: b3283; Escherichia coli O157:H7 ortholog: z4654.


ensembl_gene_id: c4045
symbol: smg
gene_biotype: protein_coding
description:
  Protein smg; Escherichia coli K-12 ortholog: b3284; Escherichia coli O157:H7 ortholog: z4655; Belongs to the Smg family.


ensembl_gene_id: c4046
symbol: smf
gene_biotype: protein_coding
description:
  Unknown protein fragment 1; Escherichia coli K-12 ortholog: b3286; Escherichia coli O157:H7 ortholog: z4656.


ensembl_gene_id: c4047
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity); Belongs to the polypeptide deformylase family.


ensembl_gene_id: c4048
symbol: fmt
gene_biotype: protein_coding
description:
  Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.


ensembl_gene_id: c4050
symbol: trkA
gene_biotype: protein_coding
description:
  Trk system potassium uptake protein trkA; Part of the constitutive potassium transport systems TrkG and TrkH. May regulate the transport activity of TrkG and TrkH systems. Binds to NAD(+) and NADH (By similarity).


ensembl_gene_id: c4051
symbol: mscL
gene_biotype: protein_coding
description:
  Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: c4052
symbol: yhdL
gene_biotype: protein_coding
description:
  Putative regulator; Residues 1 to 72 of 72 are 98.61 pct identical to residues 1 to 72 of 72 from SwissProt.40 : >sp|P36675|YHDL_ECOLI Hypothetical protein yhdL.


ensembl_gene_id: c4053
symbol: yhdM
gene_biotype: protein_coding
description:
  Zn(II)-responsive regulator of zntA; Escherichia coli K-12 ortholog: b3292; Escherichia coli O157:H7 ortholog: z4662.


ensembl_gene_id: c4054
symbol: yhdN
gene_biotype: protein_coding
description:
  Hypothetical protein yhdN; Escherichia coli K-12 ortholog: b3293; Escherichia coli O157:H7 ortholog: z4663.


ensembl_gene_id: c4055
symbol: rplQ
gene_biotype: protein_coding
description:
  50S ribosomal protein L17; Escherichia coli K-12 ortholog: b3294; Escherichia coli O157:H7 ortholog: z4664.


ensembl_gene_id: c4056
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: c4057
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of two assembly initiator proteins for the 30S subunit, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. Protein S4 is also a translational repressor protein, it controls the translation of the alpha-operon (which codes for S13, S11, S4, RNA polymerase alpha subunit, and L17) by binding to its mRNA.


ensembl_gene_id: c4058
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome (By similarity); Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: c4060
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the E.coli 70S ribosome in the initiation state it has been modeled to contact the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; bridge B1a is broken in the model with bound EF-G, while the protein-protein contacts between S13 and L5 in B1b change. Contacts the tRNAs in the A and P sites (By similarity); Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: c4061
symbol: prlA
gene_biotype: protein_coding
description:
  Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: c4062
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: c4063
symbol: rpmD
gene_biotype: protein_coding
description:
  50S ribosomal protein L30; Escherichia coli K-12 ortholog: b3302; Escherichia coli O157:H7 ortholog: z4672; Belongs to the universal ribosomal protein uL30 family.


ensembl_gene_id: c4065
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: c4066
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: c4068
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: c4070
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: c4071
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: c4072
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: c4073
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: c4075
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: c4076
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: c4077
symbol: rpmC
gene_biotype: protein_coding
description:
  50S ribosomal protein L29; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: c4079
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: c4080
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity). Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: c4082
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).


ensembl_gene_id: c4083
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: c4085
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: c4087
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: c4089
symbol: rplD
gene_biotype: protein_coding
description:
  50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. Forms part of the polypeptide exit tunnel. Belongs to the universal ribosomal protein uL4 family.


ensembl_gene_id: c4091
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: c4092
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: c4097
symbol: yheG
gene_biotype: protein_coding
description:
  Probable general secretion pathway protein E; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: c4098
symbol: hofF
gene_biotype: protein_coding
description:
  Putative general secretion pathway protein F; Protein transport protein hofF; Escherichia coli K-12 ortholog: b3327.


ensembl_gene_id: c4099
symbol: hofG
gene_biotype: protein_coding
description:
  Putative general secretion pathway protein G precursor; Protein transport protein hofG; Escherichia coli K-12 ortholog: b3328.


ensembl_gene_id: c4100
symbol: hofH
gene_biotype: protein_coding
description:
  Putative general secretion pathway protein H precursor; Protein transport protein hofH; Escherichia coli K-12 ortholog: b3329.


ensembl_gene_id: c4101
symbol: yheH
gene_biotype: protein_coding
description:
  Probable general secretion pathway protein I precursor; Escherichia coli K-12 ortholog: b3330; Escherichia coli O157:H7 ortholog: z5741.


ensembl_gene_id: c4104
symbol: yheK
gene_biotype: protein_coding
description:
  Probable general secretion pathway protein L; Escherichia coli K-12 ortholog: b3333; Escherichia coli O157:H7 ortholog: z2633.


ensembl_gene_id: c4105
symbol: pshM
gene_biotype: protein_coding
description:
  Putative general secretion pathway protein M; Transport protein pshM; Escherichia coli K-12 ortholog: b3334.


ensembl_gene_id: c4106
symbol: hofD
gene_biotype: protein_coding
description:
  Type 4 prepilin-like proteins leader peptide processing enzyme; Escherichia coli K-12 ortholog: b3335; Escherichia coli O157:H7 ortholog: z4693; bifunctional; Leader peptidase; N-methyltransferase; Belongs to the peptidase A24 family.


ensembl_gene_id: c4107
symbol: bfr
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.


ensembl_gene_id: c4108
symbol: yheA
gene_biotype: protein_coding
description:
  Bacterioferritin-associated ferredoxin; Seems to associate with BFR; could be a general redox and/or regulatory component participating in the iron storage mobilization functions of BFR. Could participate in the release or the delivery of iron from/to bacterioferritin (or other iron complexes) (By similarity).


ensembl_gene_id: c4109
symbol: yheB
gene_biotype: protein_coding
description:
  Probable bifunctional chitinase/lysozyme precursor; Escherichia coli K-12 ortholog: b3338bifunctional; Chitinase; Lysozyme.


ensembl_gene_id: c4111
symbol: tufA
gene_biotype: protein_coding
description:
  Elongation factor Tu; EF-Tu; Escherichia coli K-12 ortholog: b3339; Escherichia coli O157:H7 ortholog: z4697.


ensembl_gene_id: c4112
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...]


ensembl_gene_id: c4113
symbol: c4113
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 8 to 142 of 144 are 42.96 pct identical to residues 55 to 189 of 197 from GenPept.129 : >gb|AAF63989.1| (AF214675) unknown in vivo-induced protein 131-19 [Pseudomonas aeruginosa].


ensembl_gene_id: c4114
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: c4117
symbol: yheL
gene_biotype: protein_coding
description:
  Hypothetical protein yheL; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: c4118
symbol: yheM
gene_biotype: protein_coding
description:
  Hypothetical protein yheM; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: c4119
symbol: yheN
gene_biotype: protein_coding
description:
  Hypothetical protein yheN; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.


ensembl_gene_id: c4120
symbol: yheO
gene_biotype: protein_coding
description:
  Hypothetical protein yheO; Escherichia coli K-12 ortholog: b3346; Escherichia coli O157:H7 ortholog: z4704; To H.influenzae HI_0575.


ensembl_gene_id: c4121
symbol: fkpA
gene_biotype: protein_coding
description:
  FKBP-type peptidyl-prolyl cis-trans isomerase fkpA precursor; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


ensembl_gene_id: c4122
symbol: slyX
gene_biotype: protein_coding
description:
  SlyX protein; Escherichia coli K-12 ortholog: b3348; Escherichia coli O157:H7 ortholog: z4706; Belongs to the SlyX family.


ensembl_gene_id: c4123
symbol: slyD
gene_biotype: protein_coding
description:
  FKBP-type peptidyl-prolyl cis-trans isomerase slyD; Folding helper with both chaperone and peptidyl-prolyl cis- trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa- Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction. SlyD could be involved in Tat-d [...]


ensembl_gene_id: c4125
symbol: kefB
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein kefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.


ensembl_gene_id: c4126
symbol: yheR
gene_biotype: protein_coding
description:
  Putative NAD(P)H oxidoreductase yheR; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.


ensembl_gene_id: c4127
symbol: yheS
gene_biotype: protein_coding
description:
  Hypothetical ABC transporter ATP-binding protein yheS; Genetic data indicate it may be involved in ribosome assembly or function (Probable). Ectopic expression exacerbates the cold- sensitive growth phenotype of a bipA deletion. Belongs to the ABC transporter superfamily. ABCF family. YheS subfamily.


ensembl_gene_id: c4128
symbol: yheT
gene_biotype: protein_coding
description:
  Hypothetical protein yheT; Escherichia coli K-12 ortholog: b3353; Escherichia coli O157:H7 ortholog: z4714.


ensembl_gene_id: c4129
symbol: yheU
gene_biotype: protein_coding
description:
  Hypothetical protein yheU; Escherichia coli K-12 ortholog: b3354; Escherichia coli O157:H7 ortholog: z4715; Belongs to the UPF0270 family.


ensembl_gene_id: c4130
symbol: prkB
gene_biotype: protein_coding
description:
  Probable phosphoribulokinase; Escherichia coli K-12 ortholog: b3355; Escherichia coli O157:H7 ortholog: z4716.


ensembl_gene_id: c4131
symbol: yhfA
gene_biotype: protein_coding
description:
  Hypothetical protein yhfA; Escherichia coli K-12 ortholog: b3356; Escherichia coli O157:H7 ortholog: z4717.


ensembl_gene_id: c4132
symbol: crp
gene_biotype: protein_coding
description:
  Catabolite gene activator; A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. Plays a major role in carbon catabolite repression (CCR) (By similarity).


ensembl_gene_id: c4133
symbol: yhfK
gene_biotype: protein_coding
description:
  Hypothetical protein yhfK; Escherichia coli K-12 ortholog: b3358; Escherichia coli O157:H7 ortholog: z4719.


ensembl_gene_id: c4135
symbol: pabA
gene_biotype: protein_coding
description:
  Para-aminobenzoate synthase glutamine amidotransferase component II; Escherichia coli K-12 ortholog: b3360; Escherichia coli O157:H7 ortholog: z4721.


ensembl_gene_id: c4136
symbol: fic
gene_biotype: protein_coding
description:
  Cell filamentation protein fic; Escherichia coli K-12 ortholog: b3361; Escherichia coli O157:H7 ortholog: z4722.


ensembl_gene_id: c4137
symbol: yhfG
gene_biotype: protein_coding
description:
  Hypothetical protein yhfG; Escherichia coli K-12 ortholog: b3362; Escherichia coli O157:H7 ortholog: z4723.


ensembl_gene_id: c4138
symbol: ppiA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase A precursor; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).


ensembl_gene_id: c4139
symbol: yhfC
gene_biotype: protein_coding
description:
  Hypothetical protein yhfC; Escherichia coli K-12 ortholog: b3364; Escherichia coli O157:H7 ortholog: z4725.


ensembl_gene_id: c4141
symbol: nirB
gene_biotype: protein_coding
description:
  Nitrite reductase [NAD(P)H] large subunit; Escherichia coli K-12 ortholog: b3365; Escherichia coli O157:H7 ortholog: z4726; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: c4142
symbol: nirD
gene_biotype: protein_coding
description:
  Nitrite reductase [NAD(P)H] small subunit; Escherichia coli K-12 ortholog: b3366; Escherichia coli O157:H7 ortholog: z4727.


ensembl_gene_id: c4143
symbol: nirC
gene_biotype: protein_coding
description:
  Potential nitrite transporter; Escherichia coli K-12 ortholog: b3367; Escherichia coli O157:H7 ortholog: z4728.


ensembl_gene_id: c4144
symbol: cysG
gene_biotype: protein_coding
description:
  Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.


ensembl_gene_id: c4145
symbol: yhfL
gene_biotype: protein_coding
description:
  Hypothetical protein yhfL; Escherichia coli K-12 ortholog: b3369; Escherichia coli O157:H7 ortholog: z4730.


ensembl_gene_id: c4154
symbol: trpS
gene_biotype: protein_coding
description:
  Tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: c4155
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: c4156
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: c4159
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: c4160
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: c4161
symbol: hofQ
gene_biotype: protein_coding
description:
  Protein transport protein hofQ precursor; Escherichia coli K-12 ortholog: b3391; Escherichia coli O157:H7 ortholog: z4744.


ensembl_gene_id: c4162
symbol: yrfA
gene_biotype: protein_coding
description:
  Hypothetical protein yrfA; Escherichia coli K-12 ortholog: b3392; Escherichia coli O157:H7 ortholog: z4746.


ensembl_gene_id: c4163
symbol: yrfB
gene_biotype: protein_coding
description:
  Hypothetical protein yrfB; Escherichia coli K-12 ortholog: b3393; Escherichia coli O157:H7 ortholog: z4747.


ensembl_gene_id: c4164
symbol: yrfC
gene_biotype: protein_coding
description:
  Hypothetical protein yrfC; Escherichia coli K-12 ortholog: b3394; Escherichia coli O157:H7 ortholog: z4748.


ensembl_gene_id: c4165
symbol: yrfD
gene_biotype: protein_coding
description:
  Hypothetical protein yrfD; Escherichia coli K-12 ortholog: b3395; Escherichia coli O157:H7 ortholog: z4749.


ensembl_gene_id: c4166
symbol: mrcA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1A; PBP-1a; Escherichia coli K-12 ortholog: b3396; Escherichia coli O157:H7 ortholog: z4750.


ensembl_gene_id: c4167
symbol: yrfE
gene_biotype: protein_coding
description:
  ADP compounds hydrolase nudE; Escherichia coli K-12 ortholog: b3397; Escherichia coli O157:H7 ortholog: z4751.


ensembl_gene_id: c4169
symbol: yrfF
gene_biotype: protein_coding
description:
  Putative membrane protein igaA homolog; Escherichia coli K-12 ortholog: b3398; Escherichia coli O157:H7 ortholog: z4752.


ensembl_gene_id: c4170
symbol: yrfG
gene_biotype: protein_coding
description:
  Hypothetical protein yrfG; Escherichia coli K-12 ortholog: b3399; Escherichia coli O157:H7 ortholog: z4753.


ensembl_gene_id: c4171
symbol: yrfH
gene_biotype: protein_coding
description:
  Heat shock protein 15; Involved in the recycling of free 50S ribosomal subunits that still carry a nascent chain. Binds RNA more specifically than DNA. Binds with very high affinity to the free 50S ribosomal subunit. Does not bind it when it is part of the 70S ribosome (By similarity).


ensembl_gene_id: c4172
symbol: yrfI
gene_biotype: protein_coding
description:
  Heat shock protein 33; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: c4173
symbol: yhgE
gene_biotype: protein_coding
description:
  Hypothetical protein yhgE; Escherichia coli K-12 ortholog: b3402; Escherichia coli O157:H7 ortholog: z4756.


ensembl_gene_id: c4176
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: c4179
symbol: c4179
gene_biotype: protein_coding
description:
  Hypothetical protein yiaG; Escherichia coli K-12 ortholog: b3555; Escherichia coli O157:H7 ortholog: z4980.


ensembl_gene_id: c4180
symbol: envZ
gene_biotype: protein_coding
description:
  Osmolarity sensor protein envZ; Escherichia coli K-12 ortholog: b3404; Escherichia coli O157:H7 ortholog: z4759.


ensembl_gene_id: c4181
symbol: ompR
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein ompR; Member of the two-component regulatory system EnvZ/OmpR involved in osmoregulation (particularly of genes ompF and ompC) as well as other genes. Plays a central role in both acid and osmotic stress responses. Binds to the promoter of both ompC and ompF; at low osmolarity it activates ompF transcription, while at high osmolarity it represses ompF and activates ompC transcription.


ensembl_gene_id: c4183
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor greB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: c4187
symbol: yhgG
gene_biotype: protein_coding
description:
  Hypothetical protein yhgG; May function as a transcriptional regulator that controls feoABC expression.


ensembl_gene_id: c4188
symbol: yhgA
gene_biotype: protein_coding
description:
  Hypothetical protein yhgA; Escherichia coli K-12 ortholog: b3411; Escherichia coli O157:H7 ortholog: z4766.


ensembl_gene_id: c4189
symbol: bioH
gene_biotype: protein_coding
description:
  BioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: c4191
symbol: yhgI
gene_biotype: protein_coding
description:
  Protein yhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: c4192
symbol: gntT
gene_biotype: protein_coding
description:
  High-affinity gluconate transporter; Gluconate permease; Escherichia coli K-12 ortholog: b3415; Escherichia coli O157:H7 ortholog: z4770.


ensembl_gene_id: c4193
symbol: malQ
gene_biotype: protein_coding
description:
  4-alpha-glucanotransferase; Escherichia coli K-12 ortholog: b3416; Escherichia coli O157:H7 ortholog: z4771.


ensembl_gene_id: c4194
symbol: malP
gene_biotype: protein_coding
description:
  Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: c4196
symbol: malT
gene_biotype: protein_coding
description:
  MalT Regulatory protein; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.


ensembl_gene_id: c4197
symbol: rtcA
gene_biotype: protein_coding
description:
  RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.


ensembl_gene_id: c4199
symbol: rtcR
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein rtcR; Escherichia coli K-12 ortholog: b3422; Escherichia coli O157:H7 ortholog: z4780.


ensembl_gene_id: c4200
symbol: glpR
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate regulon repressor; Escherichia coli K-12 ortholog: b3423; Escherichia coli O157:H7 ortholog: z4781.


ensembl_gene_id: c4202
symbol: glpE
gene_biotype: protein_coding
description:
  Thiosulfate sulfurtransferase glpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: c4203
symbol: glpD
gene_biotype: protein_coding
description:
  Aerobic glycerol-3-phosphate dehydrogenase; Escherichia coli K-12 ortholog: b3426; Escherichia coli O157:H7 ortholog: z4786; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: c4207
symbol: c4207
gene_biotype: protein_coding
description:
  Putative fimbrial adhesin precursor; Residues 41 to 313 of 336 are 27.40 pct identical to residues 28 to 290 of 351 from GenPept.129 : >gb|AAG58691.1|AE005581_3 (AE005581) putative fimbrial protein [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4208
symbol: c4208
gene_biotype: protein_coding
description:
  Putative fimbrial chaperone precursor; Residues 27 to 251 of 265 are 37.61 pct identical to residues 15 to 230 of 234 from GenPept.129 : >emb|CAD01181.1| (AL627265) fimbrial chaperone [Salmonella enterica subsp. enterica serovar Typhi].


ensembl_gene_id: c4209
symbol: c4209
gene_biotype: protein_coding
description:
  Putative minor fimbrial subunit precursor; Residues 5 to 185 of 185 are 32.24 pct identical to residues 7 to 187 of 187 from GenPept.129 : >gb|AAG55429.1|AE005284_7 (AE005284) putative fimbrial-like protein [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4210
symbol: c4210
gene_biotype: protein_coding
description:
  Putative minor fimbrial subunit precursor; Residues 1 to 150 of 150 are 32.69 pct identical to residues 36 to 181 of 181 from GenPept.129 : >gb|AAL18989.1| (AE008694) fimbrial subunit [Salmonella typhimurium LT2].


ensembl_gene_id: c4212
symbol: ycbS
gene_biotype: protein_coding
description:
  Hypothetical outer membrane usher protein ycbS precursor; Escherichia coli K-12 ortholog: b0940; Escherichia coli O157:H7 ortholog: z5915.


ensembl_gene_id: c4214
symbol: c4214
gene_biotype: protein_coding
description:
  Putative major fimbrial subunit precursor; Residues 56 to 234 of 234 are 32.96 pct identical to residues 26 to 178 of 178 from GenPept.129 : >gb|AAL22500.1| (AE008868) long polar fimbria [Salmonella typhimurium LT2].


ensembl_gene_id: c4215
symbol: glgP
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: c4217
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.


ensembl_gene_id: c4218
symbol: glgX
gene_biotype: protein_coding
description:
  Glycogen operon protein glgX; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.


ensembl_gene_id: c4219
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: c4220
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: c4221
symbol: yhgN
gene_biotype: protein_coding
description:
  Hypothetical protein yhgN; Escherichia coli K-12 ortholog: b3434; Escherichia coli O157:H7 ortholog: z4798.


ensembl_gene_id: c4223
symbol: c4223
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 6 to 340 of 699 are 37.53 pct identical to residues 14 to 331 of 610 from MG1655 : b3822.


ensembl_gene_id: c4224
symbol: gntU
gene_biotype: protein_coding
description:
  Low-affinity gluconate transport permease protein, interrupted; Escherichia coli K-12 ortholog: b3436; Escherichia coli O157:H7 ortholog: z4804.


ensembl_gene_id: c4225
symbol: gntK
gene_biotype: protein_coding
description:
  Thermoresistant gluconokinase; Escherichia coli K-12 ortholog: b3437; Escherichia coli O157:H7 ortholog: z4805.


ensembl_gene_id: c4227
symbol: gntR
gene_biotype: protein_coding
description:
  Gluconate utilization system GNT-I transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon.


ensembl_gene_id: c4228
symbol: yhhW
gene_biotype: protein_coding
description:
  Protein yhhW; Escherichia coli K-12 ortholog: b3439; Escherichia coli O157:H7 ortholog: z4807; Belongs to the pirin family.


ensembl_gene_id: c4229
symbol: yhhX
gene_biotype: protein_coding
description:
  Putative oxidoreductase yhhX; Escherichia coli K-12 ortholog: b3440; Escherichia coli O157:H7 ortholog: z4808.


ensembl_gene_id: c4236
symbol: ggt
gene_biotype: protein_coding
description:
  Gamma-glutamyltranspeptidase precursor; Escherichia coli K-12 ortholog: b3447; Escherichia coli O157:H7 ortholog: z4813.


ensembl_gene_id: c4237
symbol: yhhA
gene_biotype: protein_coding
description:
  Hypothetical protein yhhA precursor; ORFQ; Escherichia coli K-12 ortholog: b3448; Escherichia coli O157:H7 ortholog: z4815.


ensembl_gene_id: c4238
symbol: ugpQ
gene_biotype: protein_coding
description:
  Glycerophosphoryl diester phosphodiesterase; Escherichia coli K-12 ortholog: b3449; Escherichia coli O157:H7 ortholog: z4817.


ensembl_gene_id: c4239
symbol: ugpC
gene_biotype: protein_coding
description:
  SN-glycerol-3-phosphate transport ATP-binding protein ugpC; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: c4240
symbol: ugpE
gene_biotype: protein_coding
description:
  SN-glycerol-3-phosphate transport system permease protein ugpE; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: c4241
symbol: ugpA
gene_biotype: protein_coding
description:
  SN-glycerol-3-phosphate transport system permease protein ugpA; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: c4242
symbol: ugpB
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate-binding periplasmic protein precursor; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE.


ensembl_gene_id: c4244
symbol: livF
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport ATP-binding protein livF; LIV-I protein F; Escherichia coli K-12 ortholog: b3454; Escherichia coli O157:H7 ortholog: z4824; Belongs to the ABC transporter superfamily.


ensembl_gene_id: c4245
symbol: livG
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport ATP-binding protein livG; LIV-I protein G; Escherichia coli K-12 ortholog: b3455; Escherichia coli O157:H7 ortholog: z4825.


ensembl_gene_id: c4246
symbol: livM
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permease protein livM; LIV-I protein M; Escherichia coli K-12 ortholog: b3456; Escherichia coli O157:H7 ortholog: z4826; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: c4247
symbol: livH
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permease protein livH; LIV-I protein H; Escherichia coli K-12 ortholog: b3457; Escherichia coli O157:H7 ortholog: z4827; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: c4248
symbol: livK
gene_biotype: protein_coding
description:
  Leucine-specific binding protein precursor; LS-BP; Escherichia coli K-12 ortholog: b3458; Escherichia coli O157:H7 ortholog: z4829.


ensembl_gene_id: c4251
symbol: yhhK
gene_biotype: protein_coding
description:
  Hypothetical protein yhhK; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family.


ensembl_gene_id: c4252
symbol: c4252
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 4 to 40 of 40 are 91.89 pct identical to residues 134 to 170 of 170 from GenPept.129 : >gb|AAA83882.1| (J05516) ORF19; putative [Escherichia coli].


ensembl_gene_id: c4253
symbol: livJ
gene_biotype: protein_coding
description:
  Leu/Ile/Val-binding protein precursor; This protein is a component of the leucine, isoleucine, valine, (threonine) transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high- affinity transport of the branched-chain amino acids; Belongs to the leucine-binding protein family.


ensembl_gene_id: c4254
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: c4255
symbol: ftsX
gene_biotype: protein_coding
description:
  Cell division protein ftsX; Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. Encoded in an operon consisting of genes ftsY, ftsE and ftsX (By similarity).


ensembl_gene_id: c4256
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein ftsE; Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.


ensembl_gene_id: c4257
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division protein ftsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: c4258
symbol: yhhF
gene_biotype: protein_coding
description:
  Putative methylase yhhF; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: c4259
symbol: yhhL
gene_biotype: protein_coding
description:
  Hypothetical protein yhhL; Escherichia coli K-12 ortholog: b3466; Escherichia coli O157:H7 ortholog: z4840.


ensembl_gene_id: c4260
symbol: yhhM
gene_biotype: protein_coding
description:
  Hypothetical protein yhhM; Escherichia coli K-12 ortholog: b3467; Escherichia coli O157:H7 ortholog: z4841.


ensembl_gene_id: c4261
symbol: yhhN
gene_biotype: protein_coding
description:
  Hypothetical protein yhhN; Escherichia coli K-12 ortholog: b3468; Escherichia coli O157:H7 ortholog: z4842.


ensembl_gene_id: c4262
symbol: zntA
gene_biotype: protein_coding
description:
  Lead, cadmium, zinc and mercury transporting ATPase; Escherichia coli K-12 ortholog: b3469; Escherichia coli O157:H7 ortholog: z4843.


ensembl_gene_id: c4263
symbol: yhhP
gene_biotype: protein_coding
description:
  SirA protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.


ensembl_gene_id: c4264
symbol: yhhQ
gene_biotype: protein_coding
description:
  Hypothetical protein yhhQ; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: c4265
symbol: c4265
gene_biotype: protein_coding
description:
  DcrB protein precursor; Escherichia coli K-12 ortholog: b3472; Escherichia coli O157:H7 ortholog: z4846.


ensembl_gene_id: c4266
symbol: yhhS
gene_biotype: protein_coding
description:
  Hypothetical protein yhhS; Escherichia coli K-12 ortholog: b3473; Escherichia coli O157:H7 ortholog: z4847.


ensembl_gene_id: c4267
symbol: yhhT
gene_biotype: protein_coding
description:
  Hypothetical protein yhhT; Escherichia coli K-12 ortholog: b3474; Escherichia coli O157:H7 ortholog: z4848.


ensembl_gene_id: c4268
symbol: yhhU
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase acpT; Escherichia coli K-12 ortholog: b3475; Escherichia coli O157:H7 ortholog: z4867; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: c4269
symbol: nikA
gene_biotype: protein_coding
description:
  Nickel-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b3476; Escherichia coli O157:H7 ortholog: z4868.


ensembl_gene_id: c4270
symbol: nikB
gene_biotype: protein_coding
description:
  Nickel transport system permease protein nikB; Escherichia coli K-12 ortholog: b3477; Escherichia coli O157:H7 ortholog: z4869.


ensembl_gene_id: c4271
symbol: nikC
gene_biotype: protein_coding
description:
  Nickel transport system permease protein nikC; Escherichia coli K-12 ortholog: b3478; Escherichia coli O157:H7 ortholog: z4870.


ensembl_gene_id: c4272
symbol: nikD
gene_biotype: protein_coding
description:
  Nickel transport ATP-binding protein nikD; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.


ensembl_gene_id: c4273
symbol: nikE
gene_biotype: protein_coding
description:
  Nickel transport ATP-binding protein nikE; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.


ensembl_gene_id: c4274
symbol: yhhG
gene_biotype: protein_coding
description:
  Nickel responsive regulator; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel (By similarity).


ensembl_gene_id: c4279
symbol: c4279
gene_biotype: protein_coding
description:
  PTS system, galactitol-specific IIC component; EIIC-GAT; Escherichia coli K-12 ortholog: b2092; Escherichia coli O157:H7 ortholog: z4877.


ensembl_gene_id: c4282
symbol: c4282
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 43 of 43 are 95.34 pct identical to residues 460 to 502 of 502 from GenPept.129 : >gb|AAG58613.1|AE005572_11 (AE005572) putative xylulose kinase [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4285
symbol: yhhJ
gene_biotype: protein_coding
description:
  Hypothetical protein yhhJ; Escherichia coli K-12 ortholog: b3485; Escherichia coli O157:H7 ortholog: z4884.


ensembl_gene_id: c4286
symbol: yhiH
gene_biotype: protein_coding
description:
  Hypothetical ABC transporter ATP-binding protein yhiH; Escherichia coli K-12 ortholog: b3486; Escherichia coli O157:H7 ortholog: z4885.


ensembl_gene_id: c4287
symbol: yhiI
gene_biotype: protein_coding
description:
  Hypothetical protein yhiI precursor; Escherichia coli K-12 ortholog: b3487; Escherichia coli O157:H7 ortholog: z4886.


ensembl_gene_id: c4289
symbol: yhiM
gene_biotype: protein_coding
description:
  Hypothetical protein yhiM; Escherichia coli K-12 ortholog: b3491; Escherichia coli O157:H7 ortholog: z4890.


ensembl_gene_id: c4290
symbol: yhiN
gene_biotype: protein_coding
description:
  Hypothetical protein yhiN; Escherichia coli K-12 ortholog: b3492; Escherichia coli O157:H7 ortholog: z4891.


ensembl_gene_id: c4291
symbol: pitA
gene_biotype: protein_coding
description:
  Low-affinity inorganic phosphate transporter 1; Low-affinity inorganic phosphate transport. Can also transport arsenate (By similarity); Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.


ensembl_gene_id: c4292
symbol: yhiO
gene_biotype: protein_coding
description:
  Universal stress protein B; Escherichia coli K-12 ortholog: b3494; Escherichia coli O157:H7 ortholog: z4894.


ensembl_gene_id: c4295
symbol: yhiP
gene_biotype: protein_coding
description:
  Hypothetical transporter yhiP; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily.


ensembl_gene_id: c4299
symbol: gor
gene_biotype: protein_coding
description:
  Glutathione reductase; Escherichia coli K-12 ortholog: b3500; Escherichia coli O157:H7 ortholog: z4900.


ensembl_gene_id: c4301
symbol: arsC
gene_biotype: protein_coding
description:
  Arsenate reductase; Escherichia coli K-12 ortholog: b3503; Escherichia coli O157:H7 ortholog: z4905.


ensembl_gene_id: c4303
symbol: c4303
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 1 to 53 of 57 are 86.79 pct identical to residues 1 to 53 of 260 from MG1655 : b3504.


ensembl_gene_id: c4304
symbol: slp
gene_biotype: protein_coding
description:
  Outer membrane protein slp precursor; Escherichia coli K-12 ortholog: b3506; Escherichia coli O157:H7 ortholog: z4908.


ensembl_gene_id: c4312
symbol: c4312
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 48 of 49 are 79.16 pct identical to residues 1 to 48 of 94 from GenPept.129 : >gb|AAG58642.1|AE005576_1 (AE005576) Z4912 gene product [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4314
symbol: chuW
gene_biotype: protein_coding
description:
  Putative oxygen independent coproporphyrinogen III oxidase; Escherichia coli O157:H7 ortholog: z4914.


ensembl_gene_id: c4317
symbol: chuU
gene_biotype: protein_coding
description:
  Putative permease of iron compound ABC transport system; Escherichia coli O157:H7 ortholog: z4918; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: c4318
symbol: hmuV
gene_biotype: protein_coding
description:
  Putative ATP-binding protein of ABC transport system; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: c4319
symbol: yhiD
gene_biotype: protein_coding
description:
  Hypothetical protein yhiD; Escherichia coli K-12 ortholog: b3508; Escherichia coli O157:H7 ortholog: z4920.


ensembl_gene_id: c4320
symbol: hdeB
gene_biotype: protein_coding
description:
  Protein hdeB precursor; Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. Belongs to the HdeB family.


ensembl_gene_id: c4321
symbol: hdeA
gene_biotype: protein_coding
description:
  Protein hdeA precursor; Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Belongs to the HdeA family.


ensembl_gene_id: c4323
symbol: yhiE
gene_biotype: protein_coding
description:
  Hypothetical protein yhiE; Regulates the expression of several genes involved in acid resistance. Required for the expression of gadA and gadBC, among others, regardless of media or growth conditions. Binds directly to the 20 bp GAD box found in the control regions of both loci (By similarity).


ensembl_gene_id: c4324
symbol: yhiU
gene_biotype: protein_coding
description:
  Hypothetical lipoprotein yhiU precursor; Part of the tripartite efflux system MdtEF-TolC, which confers resistance to various compounds.


ensembl_gene_id: c4325
symbol: yhiV
gene_biotype: protein_coding
description:
  Hypothetical protein yhiV; Part of the tripartite efflux system MdtEF-TolC, which confers resistance to various compounds.


ensembl_gene_id: c4326
symbol: yhiW
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yhiW; Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC. Repression occurs directly or via the repression of the expression of gadX. Activation occurs directly by the binding of GadW to the gadA and gadBC promoters (By similarity).


ensembl_gene_id: c4327
symbol: yhiX
gene_biotype: protein_coding
description:
  Transcriptional regulator gadX; Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA, gadB and gadC. Depending on the conditions (growth phase and medium), can repress gadW (By similarity).


ensembl_gene_id: c4328
symbol: gadA
gene_biotype: protein_coding
description:
  Glutamate decarboxylase alpha; Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria (By similarity).


ensembl_gene_id: c4329
symbol: yhjA
gene_biotype: protein_coding
description:
  Probable cytochrome C peroxidase; Escherichia coli K-12 ortholog: b3518; Escherichia coli O157:H7 ortholog: z4931.


ensembl_gene_id: c4330
symbol: treF
gene_biotype: protein_coding
description:
  Probable cytoplasmic trehalase; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.


ensembl_gene_id: c4331
symbol: yhjB
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yhjB; Escherichia coli K-12 ortholog: b3520; Escherichia coli O157:H7 ortholog: z4933.


ensembl_gene_id: c4332
symbol: yhjC
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yhjC; Escherichia coli K-12 ortholog: b3521; Escherichia coli O157:H7 ortholog: z4934; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: c4333
symbol: yhjD
gene_biotype: protein_coding
description:
  Hypothetical protein yhjD; Escherichia coli K-12 ortholog: b3522; Escherichia coli O157:H7 ortholog: z4935.


ensembl_gene_id: c4334
symbol: yhjE
gene_biotype: protein_coding
description:
  Hypothetical metabolite transport protein yhjE; Escherichia coli K-12 ortholog: b3523; Escherichia coli O157:H7 ortholog: z4936.


ensembl_gene_id: c4335
symbol: yhjG
gene_biotype: protein_coding
description:
  Hypothetical protein yhjG; Escherichia coli K-12 ortholog: b3524; Escherichia coli O157:H7 ortholog: z4937.


ensembl_gene_id: c4336
symbol: yhjH
gene_biotype: protein_coding
description:
  Hypothetical protein yhjH; Escherichia coli K-12 ortholog: b3525; Escherichia coli O157:H7 ortholog: z4939.


ensembl_gene_id: c4337
symbol: kdgK
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxygluconokinase; Escherichia coli K-12 ortholog: b3526; Escherichia coli O157:H7 ortholog: z4940.


ensembl_gene_id: c4339
symbol: yhjJ
gene_biotype: protein_coding
description:
  Protein yhjJ precursor; Escherichia coli K-12 ortholog: b3527; Escherichia coli O157:H7 ortholog: z4941.


ensembl_gene_id: c4340
symbol: dctA
gene_biotype: protein_coding
description:
  Aerobic C4-dicarboxylate transport protein; Responsible for the aerobic transport of the dicarboxylates fumarate and malate and to a lesser extent succinate, from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: c4342
symbol: yhjL
gene_biotype: protein_coding
description:
  Cellulose synthase operon protein C; Escherichia coli K-12 ortholog: b3530; Escherichia coli O157:H7 ortholog: z4944.


ensembl_gene_id: c4343
symbol: yhjM
gene_biotype: protein_coding
description:
  Endoglucanase precursor; Escherichia coli K-12 ortholog: b3531; Escherichia coli O157:H7 ortholog: z4946; Belongs to the glycosyl hydrolase 8 (cellulase D) family.


ensembl_gene_id: c4344
symbol: yhjN
gene_biotype: protein_coding
description:
  Cyclic di-GMP binding protein precursor; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: c4345
symbol: yhjO
gene_biotype: protein_coding
description:
  Cellulose synthase catalytic subunit (UDP-forming); Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.


ensembl_gene_id: c4346
symbol: yhjQ
gene_biotype: protein_coding
description:
  Hypothetical protein yhjQ; Escherichia coli K-12 ortholog: b3534; Escherichia coli O157:H7 ortholog: z4949.


ensembl_gene_id: c4347
symbol: yhjR
gene_biotype: protein_coding
description:
  Hypothetical protein yhjR; Escherichia coli K-12 ortholog: b3535; Escherichia coli O157:H7 ortholog: z4951.


ensembl_gene_id: c4348
symbol: yhjS
gene_biotype: protein_coding
description:
  Hypothetical protein yhjS; Escherichia coli K-12 ortholog: b3536; Escherichia coli O157:H7 ortholog: z4952.


ensembl_gene_id: c4349
symbol: yhjT
gene_biotype: protein_coding
description:
  Hypothetical protein yhjT; Escherichia coli K-12 ortholog: b3537; Escherichia coli O157:H7 ortholog: z4953.


ensembl_gene_id: c4350
symbol: yhjU
gene_biotype: protein_coding
description:
  Hypothetical protein yhjU; Escherichia coli K-12 ortholog: b3538; Escherichia coli O157:H7 ortholog: z4954.


ensembl_gene_id: c4354
symbol: yhjV
gene_biotype: protein_coding
description:
  Hypothetical transport protein yhjV; Escherichia coli K-12 ortholog: b3539; Escherichia coli O157:H7 ortholog: z4956.


ensembl_gene_id: c4355
symbol: dppF
gene_biotype: protein_coding
description:
  Dipeptide transport ATP-binding protein dppF; Escherichia coli K-12 ortholog: b3540; Escherichia coli O157:H7 ortholog: z4957; Belongs to the ABC transporter superfamily.


ensembl_gene_id: c4356
symbol: dppD
gene_biotype: protein_coding
description:
  Dipeptide transport ATP-binding protein dppD; Escherichia coli K-12 ortholog: b3541; Escherichia coli O157:H7 ortholog: z4958; Belongs to the ABC transporter superfamily.


ensembl_gene_id: c4357
symbol: dppC
gene_biotype: protein_coding
description:
  Dipeptide transport system permease protein dppC; Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.


ensembl_gene_id: c4358
symbol: dppB
gene_biotype: protein_coding
description:
  Dipeptide transport system permease protein dppB; Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.


ensembl_gene_id: c4361
symbol: dppA
gene_biotype: protein_coding
description:
  Periplasmic dipeptide transport protein precursor; Dipeptide-binding protein; Escherichia coli K-12 ortholog: b3544; Escherichia coli O157:H7 ortholog: z4961.


ensembl_gene_id: c4364
symbol: yhjW
gene_biotype: protein_coding
description:
  Membrane-protein yhjW; Escherichia coli K-12 ortholog: b3546; Escherichia coli O157:H7 ortholog: z4964.


ensembl_gene_id: c4365
symbol: yhjX
gene_biotype: protein_coding
description:
  Hypothetical protein yhjX; Escherichia coli K-12 ortholog: b3547; Escherichia coli O157:H7 ortholog: z4972.


ensembl_gene_id: c4366
symbol: yhjY
gene_biotype: protein_coding
description:
  Hypothetical protein yhjY; Escherichia coli K-12 ortholog: b3548; Escherichia coli O157:H7 ortholog: z4973.


ensembl_gene_id: c4367
symbol: tag
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase I; Escherichia coli K-12 ortholog: b3549; Escherichia coli O157:H7 ortholog: z4974.


ensembl_gene_id: c4368
symbol: yiaC
gene_biotype: protein_coding
description:
  Hypothetical acetyltransferase yiaC; Escherichia coli K-12 ortholog: b3550; Escherichia coli O157:H7 ortholog: z4975.


ensembl_gene_id: c4369
symbol: bisC
gene_biotype: protein_coding
description:
  Biotin sulfoxide reductase; Escherichia coli K-12 ortholog: b3551; Escherichia coli O157:H7 ortholog: z4976; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: c4370
symbol: yiaD
gene_biotype: protein_coding
description:
  Hypothetical lipoprotein yiaD precursor; Escherichia coli K-12 ortholog: b3552; Escherichia coli O157:H7 ortholog: z4977.


ensembl_gene_id: c4372
symbol: yiaE
gene_biotype: protein_coding
description:
  2-ketogluconate reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.


ensembl_gene_id: c4373
symbol: yiaF
gene_biotype: protein_coding
description:
  Hypothetical protein yiaF; Escherichia coli K-12 ortholog: b3554; Escherichia coli O157:H7 ortholog: z4979.


ensembl_gene_id: c4377
symbol: cspA
gene_biotype: protein_coding
description:
  Cold shock protein cspA; Binds to and stimulates the transcription of the CCAAT- containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3' (By similarity).


ensembl_gene_id: c4378
symbol: glyS
gene_biotype: protein_coding
description:
  Glycyl-tRNA synthetase beta chain; Escherichia coli K-12 ortholog: b3559; Escherichia coli O157:H7 ortholog: z4983.


ensembl_gene_id: c4379
symbol: glyQ
gene_biotype: protein_coding
description:
  Glycyl-tRNA synthetase alpha chain; Escherichia coli K-12 ortholog: b3560; Escherichia coli O157:H7 ortholog: z4984.


ensembl_gene_id: c4381
symbol: yiaH
gene_biotype: protein_coding
description:
  Hypothetical protein yiaH; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.


ensembl_gene_id: c4382
symbol: yiaA
gene_biotype: protein_coding
description:
  Hypothetical protein yiaA; Escherichia coli K-12 ortholog: b3562; Escherichia coli O157:H7 ortholog: z4987.


ensembl_gene_id: c4383
symbol: yiaB
gene_biotype: protein_coding
description:
  Hypothetical protein yiaB; Escherichia coli K-12 ortholog: b3563; Escherichia coli O157:H7 ortholog: z4988.


ensembl_gene_id: c4385
symbol: xylA
gene_biotype: protein_coding
description:
  Xylose isomerase; Escherichia coli K-12 ortholog: b3565; Escherichia coli O157:H7 ortholog: z4990; Belongs to the xylose isomerase family.


ensembl_gene_id: c4386
symbol: xylF
gene_biotype: protein_coding
description:
  D-xylose-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b3566; Escherichia coli O157:H7 ortholog: z4991.


ensembl_gene_id: c4387
symbol: xylG
gene_biotype: protein_coding
description:
  D-xylose transport ATP-binding protein xylG; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.


ensembl_gene_id: c4388
symbol: xylH
gene_biotype: protein_coding
description:
  Xylose transport system permease protein xylH; Part of the binding-protein-dependent transport system for D- xylose. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.


ensembl_gene_id: c4392
symbol: malS
gene_biotype: protein_coding
description:
  Alpha-amylase precursor; Escherichia coli K-12 ortholog: b3571; Escherichia coli O157:H7 ortholog: z4996.


ensembl_gene_id: c4393
symbol: avtA
gene_biotype: protein_coding
description:
  Valine--pyruvate aminotransferase; Escherichia coli K-12 ortholog: b3572; Escherichia coli O157:H7 ortholog: z4997.


ensembl_gene_id: c4394
symbol: yiaI
gene_biotype: protein_coding
description:
  Putative electron transport protein ysaA; Escherichia coli K-12 ortholog: b3573; Escherichia coli O157:H7 ortholog: z4998.


ensembl_gene_id: c4395
symbol: yiaJ
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yiaJ; Escherichia coli K-12 ortholog: b3574; Escherichia coli O157:H7 ortholog: z2874.


ensembl_gene_id: c4396
symbol: yiaK
gene_biotype: protein_coding
description:
  Hypothetical oxidoreductase yiaK; Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.


ensembl_gene_id: c4398
symbol: c4398
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 4 to 305 of 306 are 76.72 pct identical to residues 3 to 307 of 310 from GenPept.129 : >gb|AAL22529.1| (AE008870) putative chemotaxis protein, resembles cheA [Salmonella typhimurium LT2].


ensembl_gene_id: c4402
symbol: yiaO
gene_biotype: protein_coding
description:
  Putative ABC transporter Periplasmic binding protein yiaO precursor; Escherichia coli K-12 ortholog: b3579; Escherichia coli O157:H7 ortholog: z1284.


ensembl_gene_id: c4403
symbol: lyxK
gene_biotype: protein_coding
description:
  Cryptic L-xylulose kinase; Escherichia coli K-12 ortholog: b3580; Belongs to the FGGY kinase family.


ensembl_gene_id: c4404
symbol: sgbH
gene_biotype: protein_coding
description:
  Probable hexulose-6-phosphate synthase; Escherichia coli K-12 ortholog: b3581; Escherichia coli O157:H7 ortholog: z5805.


ensembl_gene_id: c4405
symbol: sgbU
gene_biotype: protein_coding
description:
  Putative hexulose-6-phosphate isomerase; Escherichia coli K-12 ortholog: b3582; Escherichia coli O157:H7 ortholog: z5806.


ensembl_gene_id: c4406
symbol: sgbE
gene_biotype: protein_coding
description:
  Probable sugar isomerase sgbE; Escherichia coli K-12 ortholog: b3583; Escherichia coli O157:H7 ortholog: z0069.


ensembl_gene_id: c4408
symbol: aldB
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase B; Escherichia coli K-12 ortholog: b3588; Escherichia coli O157:H7 ortholog: z5008; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: c4410
symbol: yiaY
gene_biotype: protein_coding
description:
  Probable alcohol dehydrogenase; Escherichia coli K-12 ortholog: b3589; Escherichia coli O157:H7 ortholog: z5010.


ensembl_gene_id: c4411
symbol: selB
gene_biotype: protein_coding
description:
  Selenocysteine-specific elongation factor; SelB translation factor; Escherichia coli K-12 ortholog: b3590; Escherichia coli O157:H7 ortholog: z5011.


ensembl_gene_id: c4412
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family.


ensembl_gene_id: c4413
symbol: yibF
gene_biotype: protein_coding
description:
  Hypothetical GST-like protein yibF; Escherichia coli K-12 ortholog: b3592; Escherichia coli O157:H7 ortholog: z5013; Belongs to the GST superfamily. HSP26 family.


ensembl_gene_id: c4414
symbol: yibH
gene_biotype: protein_coding
description:
  Hypothetical protein yibH; Escherichia coli K-12 ortholog: b3597; Escherichia coli O157:H7 ortholog: z5021.


ensembl_gene_id: c4415
symbol: yibI
gene_biotype: protein_coding
description:
  Hypothetical protein yibI; Escherichia coli K-12 ortholog: b3598; Escherichia coli O157:H7 ortholog: z5022.


ensembl_gene_id: c4416
symbol: mtlA
gene_biotype: protein_coding
description:
  PTS system, mannitol-specific IIABC component; EIIABC-MTL; Escherichia coli K-12 ortholog: b3599; Escherichia coli O157:H7 ortholog: z5023.


ensembl_gene_id: c4417
symbol: mtlD
gene_biotype: protein_coding
description:
  Mannitol-1-phosphate 5-dehydrogenase; Escherichia coli K-12 ortholog: b3600; Escherichia coli O157:H7 ortholog: z5024.


ensembl_gene_id: c4418
symbol: mtlR
gene_biotype: protein_coding
description:
  Mannitol operon repressor; Involved in the repression of the expression of the mannitol mtlADR operon. Does not bind the operator/promoter regulatory region of this operon. Therefore, seems to belong to a new class of transcription factors in bacteria that may regulate gene expression indirectly, perhaps as a part of a larger transcriptional complex. Belongs to the MtlR/FumE family.


ensembl_gene_id: c4419
symbol: yibT
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 67 of 69 are 77.61 pct identical to residues 1 to 67 of 69 from GenPept.129 : >gb|AAL22547.1| (AE008871) putative cytoplasmic protein [Salmonella typhimurium LT2].


ensembl_gene_id: c4421
symbol: yibL
gene_biotype: protein_coding
description:
  Hypothetical protein yibL; Escherichia coli K-12 ortholog: b3602; Escherichia coli O157:H7 ortholog: z5026.


ensembl_gene_id: c4424
symbol: upaG
gene_biotype: protein_coding
description:
  Putative adhesin; Mediates aggregation, biofilm formation and adhesion to a range of extracellular matrix (ECM) proteins, such as fibronectin, fibrinogen, laminin and collagen types I, II, III, and V. Mediates adhesion to human T24 bladder epithelial cells.


ensembl_gene_id: c4425
symbol: lldP
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force (By similarity).


ensembl_gene_id: c4426
symbol: lldR
gene_biotype: protein_coding
description:
  Putative L-lactate dehydrogenase operon Regulatory protein; Escherichia coli K-12 ortholog: b3604; Escherichia coli O157:H7 ortholog: z5031.


ensembl_gene_id: c4427
symbol: lldD
gene_biotype: protein_coding
description:
  L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.


ensembl_gene_id: c4428
symbol: yibK
gene_biotype: protein_coding
description:
  Hypothetical tRNA/rRNA methyltransferase yibK; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: c4429
symbol: cysE
gene_biotype: protein_coding
description:
  Serine acetyltransferase; Escherichia coli K-12 ortholog: b3607; Escherichia coli O157:H7 ortholog: z5034; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: c4430
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase (NAD(P)+); Escherichia coli K-12 ortholog: b3608; Escherichia coli O157:H7 ortholog: z5035; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: c4431
symbol: c4431
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 12 to 161 of 161 are 95.33 pct identical to residues 1 to 150 of 150 from SwissProt.40 : >sp|P15041|YZSB_ECOLI VERY HYPOTHETICAL 17.7 KD PROTEIN IN SECB REGION.


ensembl_gene_id: c4432
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: c4433
symbol: grxC
gene_biotype: protein_coding
description:
  Glutaredoxin 3; The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase (By similarity); Belongs to the glutaredoxin family.


ensembl_gene_id: c4436
symbol: yibN
gene_biotype: protein_coding
description:
  Hypothetical protein yibN; Escherichia coli K-12 ortholog: b3611; Escherichia coli O157:H7 ortholog: z5038.


ensembl_gene_id: c4438
symbol: yibO
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: c4439
symbol: yibP
gene_biotype: protein_coding
description:
  Hypothetical protein yibP; Escherichia coli K-12 ortholog: b3613; Escherichia coli O157:H7 ortholog: z5040.


ensembl_gene_id: c4440
symbol: yibQ
gene_biotype: protein_coding
description:
  Hypothetical protein yibQ precursor; Escherichia coli K-12 ortholog: b3614; Escherichia coli O157:H7 ortholog: z5041.


ensembl_gene_id: c4441
symbol: yibD
gene_biotype: protein_coding
description:
  Putative glycosyl transferase yibD; Escherichia coli K-12 ortholog: b3615; Escherichia coli O157:H7 ortholog: z5042.


ensembl_gene_id: c4443
symbol: tdh
gene_biotype: protein_coding
description:
  Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: c4444
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: c4445
symbol: rfaD
gene_biotype: protein_coding
description:
  ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.


ensembl_gene_id: c4446
symbol: rfaF
gene_biotype: protein_coding
description:
  ADP-heptose--LPS heptosyltransferase II; Escherichia coli K-12 ortholog: b3620; Escherichia coli O157:H7 ortholog: z5047.


ensembl_gene_id: c4447
symbol: rfaC
gene_biotype: protein_coding
description:
  Lipopolysaccharide heptosyltransferase-1; Escherichia coli K-12 ortholog: b3621; Escherichia coli O157:H7 ortholog: z5048.


ensembl_gene_id: c4448
symbol: waaL
gene_biotype: protein_coding
description:
  Lipid A-core, surface polymer ligase; Residues 1 to 417 of 417 are 96.40 pct identical to residues 1 to 417 of 417 from GenPept.129 : >gb|AAC69671.1| (AF019746) lipid A-core:surface polymer ligase WaaL [Escherichia coli].


ensembl_gene_id: c4449
symbol: waaV
gene_biotype: protein_coding
description:
  Putative beta1,3-glucosyltransferase; Residues 1 to 327 of 327 are 96.63 pct identical to residues 1 to 327 of 327 from GenPept.129 : >gb|AAC69672.1| (AF019746) putative beta1,3-glucosyltransferase WaaV [Escherichia coli].


ensembl_gene_id: c4450
symbol: waaW
gene_biotype: protein_coding
description:
  UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase; Residues 1 to 341 of 342 are 98.24 pct identical to residues 1 to 341 of 341 from GenPept.129 : >gb|AAC69673.1| (AF019746) UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase WaaW [Escherichia coli].


ensembl_gene_id: c4451
symbol: rfaY
gene_biotype: protein_coding
description:
  Lipopolysaccharide core biosynthesis protein rfaY; Escherichia coli K-12 ortholog: b3625; Escherichia coli O157:H7 ortholog: z5052.


ensembl_gene_id: c4452
symbol: rfaJ
gene_biotype: protein_coding
description:
  Lipopolysaccharide 1,2-glucosyltransferase; Escherichia coli K-12 ortholog: b3626; Escherichia coli O157:H7 ortholog: z5051.


ensembl_gene_id: c4453
symbol: rfaI
gene_biotype: protein_coding
description:
  Lipopolysaccharide 1,3-galactosyltransferase; Escherichia coli K-12 ortholog: b3627; Escherichia coli O157:H7 ortholog: z5053.


ensembl_gene_id: c4454
symbol: rfaP
gene_biotype: protein_coding
description:
  Lipopolysaccharide core biosynthesis protein rfaP; Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core; Belongs to the protein kinase superfamily. KdkA/rfaP family.


ensembl_gene_id: c4455
symbol: rfaG
gene_biotype: protein_coding
description:
  Lipopolysaccharide core biosynthesis protein rfaG; Glucosyltransferase I; Escherichia coli K-12 ortholog: b3631; Escherichia coli O157:H7 ortholog: z5055.


ensembl_gene_id: c4456
symbol: rfaQ
gene_biotype: protein_coding
description:
  Lipopolysaccharide core biosynthesis glycosyl transferase rfaQ; Escherichia coli K-12 ortholog: b3632; Escherichia coli O157:H7 ortholog: z5056.


ensembl_gene_id: c4457
symbol: kdtA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of two 3-deoxy-D-manno-octulosonate (Kdo) residues from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.


ensembl_gene_id: c4458
symbol: kdtB
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: c4459
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: c4460
symbol: rpmG
gene_biotype: protein_coding
description:
  50S ribosomal protein L33; Escherichia coli K-12 ortholog: b3636; Escherichia coli O157:H7 ortholog: z5060; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: c4461
symbol: rpmB
gene_biotype: protein_coding
description:
  50S ribosomal protein L28; Escherichia coli K-12 ortholog: b3637; Escherichia coli O157:H7 ortholog: z5061; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: c4462
symbol: radC
gene_biotype: protein_coding
description:
  DNA repair protein radC; Escherichia coli K-12 ortholog: b3638; Escherichia coli O157:H7 ortholog: z5062; Belongs to the UPF0758 family. YicR subfamily.


ensembl_gene_id: c4463
symbol: dfp
gene_biotype: protein_coding
description:
  DNA/pantothenate metabolism flavoprotein; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: c4464
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.


ensembl_gene_id: c4465
symbol: ttk
gene_biotype: protein_coding
description:
  Ttk protein; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: c4466
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: c4467
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: c4469
symbol: dinD
gene_biotype: protein_coding
description:
  DNA-damage-inducible protein D; Escherichia coli K-12 ortholog: b3645; Escherichia coli O157:H7 ortholog: z5070.


ensembl_gene_id: c4470
symbol: yicG
gene_biotype: protein_coding
description:
  Hypothetical protein yicG; Escherichia coli K-12 ortholog: b3646; Escherichia coli O157:H7 ortholog: z5071.


ensembl_gene_id: c4471
symbol: yicF
gene_biotype: protein_coding
description:
  Hypothetical DNA ligase-like protein yicF; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: c4474
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).


ensembl_gene_id: c4475
symbol: spoT
gene_biotype: protein_coding
description:
  Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: c4476
symbol: spoU
gene_biotype: protein_coding
description:
  tRNA (Guanosine-2'-O-)-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: c4477
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase recG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: c4478
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symport carrier protein; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: c4479
symbol: yicE
gene_biotype: protein_coding
description:
  Putative purine permease yicE; Specific, proton motive force-dependent high-affinity transporter for xanthine; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.


ensembl_gene_id: c4480
symbol: yicH
gene_biotype: protein_coding
description:
  Hypothetical protein yicH; Escherichia coli K-12 ortholog: b3655; Escherichia coli O157:H7 ortholog: z5083.


ensembl_gene_id: c4484
symbol: c4484
gene_biotype: protein_coding
description:
  Putative aldolase; Residues 1 to 283 of 283 are 39.78 pct identical to residues 1 to 283 of 284 from GenPept.129 : >emb|CAD00212.1| (AL591982) similar to fructose-1,6-biphosphate aldolase type II [Listeria monocytogenes].


ensembl_gene_id: c4485
symbol: c4485
gene_biotype: protein_coding
description:
  Putative PTS enzyme-ii fructose; Residues 11 to 358 of 363 are 53.10 pct identical to residues 5 to 355 of 363 from GenPept.129 : >emb|CAC97469.1| (AL596171) similar to PTS system, fructose-specific enzyme IIC component [Listeria innocua].


ensembl_gene_id: c4486
symbol: c4486
gene_biotype: protein_coding
description:
  PTS system, fructose-like-2 IIB component 1; Phosphotransferase enzyme II, B component; Escherichia coli K-12 ortholog: b3950; Escherichia coli O157:H7 ortholog: z5506.


ensembl_gene_id: c4487
symbol: c4487
gene_biotype: protein_coding
description:
  Putative phosphotransferase system (PTS), fructose-specific; Residues 1 to 149 of 156 are 48.32 pct identical to residues 6 to 154 of 157 from GenPept.129 : >emb|CAC97471.1| (AL596171) similar to PTS system, fructose-specific enzyme IIA component [Listeria innocua].


ensembl_gene_id: c4488
symbol: c4488
gene_biotype: protein_coding
description:
  Putative transcriptional Antiterminator; Residues 18 to 515 of 532 are 28.32 pct identical to residues 2 to 483 of 485 from GenPept.129 : >emb|CAD00216.1| (AL591982) similar to transcription regulator [Listeria monocytogenes].


ensembl_gene_id: c4489
symbol: yicI
gene_biotype: protein_coding
description:
  Putative family 31 glucosidase yicI; Escherichia coli K-12 ortholog: b3656; Escherichia coli O157:H7 ortholog: z5084; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: c4490
symbol: yicJ
gene_biotype: protein_coding
description:
  Hypothetical symporter yicJ; Escherichia coli K-12 ortholog: b3657; Escherichia coli O157:H7 ortholog: z5085.


ensembl_gene_id: c4491
symbol: intC
gene_biotype: protein_coding
description:
  Putative prophage integrase; Escherichia coli K-12 ortholog: b2349; Escherichia coli O157:H7 ortholog: z5087; Belongs to the 'phage' integrase family.


ensembl_gene_id: c4492
symbol: c4492
gene_biotype: protein_coding
description:
  ShiA homolog; Residues 1 to 347 of 347 are 96.82 pct identical to residues 1 to 347 of 347 from GenPept.129 : >gb|AAD44731.1|AF141323_2 (AF141323) ShiA [Shigella flexneri].


ensembl_gene_id: c4494
symbol: c4494
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Residues 9 to 364 of 364 are 54.03 pct identical to residues 1 to 359 of 360 from GenPept.129 : >emb|CAC89693.1| (AJ414145) LacI-family regulatory protein [Yersinia pestis].


ensembl_gene_id: c4496
symbol: c4496
gene_biotype: protein_coding
description:
  Putative glucosidase; Residues 3 to 213 of 217 are 62.08 pct identical to residues 2 to 212 of 792 from GenPept.129 : >emb|CAC89695.1| (AJ414145) putative glucosidase [Yersinia pestis].


ensembl_gene_id: c4497
symbol: c4497
gene_biotype: protein_coding
description:
  Putative glucosidase; Residues 13 to 581 of 594 are 74.86 pct identical to residues 213 to 781 of 792 from GenPept.129 : >emb|CAC89695.1| (AJ414145) putative glucosidase [Yersinia pestis]; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: c4499
symbol: c4499
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 69 of 70 are 98.55 pct identical to residues 1 to 69 of 70 from GenPept.129 : >gb|AAK18551.1|AF348706_240 (AF348706) putative iso-IS1 orf [Shigella flexneri].


ensembl_gene_id: c4500
symbol: c4500
gene_biotype: protein_coding
description:
  Putative amino acid antiporter; Residues 20 to 492 of 499 are 47.78 pct identical to residues 12 to 476 of 483 from GenPept.129 : >gb|AAF73583.1| (AE002332) amino acid permease [Chlamydia muridarum].


ensembl_gene_id: c4501
symbol: c4501
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 7 to 750 of 789 are 38.82 pct identical to residues 4 to 744 of 756 from MG1655 : b4117.


ensembl_gene_id: c4502
symbol: c4502
gene_biotype: protein_coding
description:
  Putative antiporter; Residues 5 to 481 of 489 are 50.10 pct identical to residues 2 to 479 of 485 from GenPept.129 : >gb|AAD19168.1| (AE001683) Arginine/Ornithine Antiporter [Chlamydophila pneumoniae CWL029].


ensembl_gene_id: c4504
symbol: insB
gene_biotype: protein_coding
description:
  Insertion element IS1 1/5/6 protein insB; Escherichia coli K-12 ortholog: b3445; Escherichia coli O157:H7 ortholog: z1562.


ensembl_gene_id: c4505
symbol: c4505
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 13 to 125 of 125 are 62.83 pct identical to residues 2 to 114 of 324 from GenPept.129 : >gb|AAL22245.1| (AE008855) putative oxidoreductase [Salmonella typhimurium LT2].


ensembl_gene_id: c4506
symbol: insI
gene_biotype: protein_coding
description:
  Transposase insI for insertion sequence element IS30B/C/D; Escherichia coli K-12 ortholog: b4284; Escherichia coli O157:H7 ortholog: z2993.


ensembl_gene_id: c4508
symbol: c4508
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Residues 1 to 61 of 61 are 98.36 pct identical to residues 477 to 537 of 537 from GenPept.129 : >gb|AAG55715.1|AE005309_5 (AE005309) unknown in ISEc8 [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4509
symbol: c4509
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 379 to 441 of 442 are 49.20 pct identical to residues 20 to 80 of 90 from GenPept.129 : >gb|AAK99647.1| (AE008459) Hypothetical protein [Streptococcus pneumoniae R6].


ensembl_gene_id: c4511
symbol: c4511
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 3 to 238 of 241 are 48.73 pct identical to residues 2 to 239 of 256 from GenPept.129 : >gb|AAL45712.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)].


ensembl_gene_id: c4512
symbol: c4512
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 30 to 392 of 439 are 40.10 pct identical to residues 20 to 375 of 423 from GenPept.129 : >gb|AAF12682.1|AE001827_20 (AE001827) hypothetical protein [Deinococcus radiodurans].


ensembl_gene_id: c4513
symbol: c4513
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 190 of 250 are 29.41 pct identical to residues 1 to 236 of 298 from GenPept.129 : >gb|AAL45714.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)].


ensembl_gene_id: c4514
symbol: c4514
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 594 of 594 are 33.00 pct identical to residues 1 to 606 of 632 from GenPept.129 : >gb|AAL45715.1| (AE008927) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)].


ensembl_gene_id: c4517
symbol: c4517
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 120 of 132 are 39.34 pct identical to residues 324 to 445 of 455 from GenPept.129 : >emb|CAC90312.1| (AJ414148) hypothetical protein [Yersinia pestis].


ensembl_gene_id: c4518
symbol: c4518
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Residues 30 to 145 of 145 are 97.41 pct identical to residues 1 to 116 of 348 from GenPept.129 : >gb|AAG55755.1|AE005312_1 (AE005312) Z1640 gene product [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4524
symbol: c4524
gene_biotype: protein_coding
description:
  Putative propanol dehydrogenase; Residues 10 to 370 of 372 are 44.41 pct identical to residues 9 to 375 of 376 from GenPept.129 : >dbj|BAB80598.1| (AP003188) NADPH-dependent butanol dehydrogenase [Clostridium perfringens].


ensembl_gene_id: c4525
symbol: c4525
gene_biotype: protein_coding
description:
  Putative chormophorylate of CpcA; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.


ensembl_gene_id: c4528
symbol: c4528
gene_biotype: protein_coding
description:
  Ethanolamine utilization protein eutN; Escherichia coli K-12 ortholog: b2456; Escherichia coli O157:H7 ortholog: z3712.


ensembl_gene_id: c4529
symbol: c4529
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 25 to 156 of 165 are 50.00 pct identical to residues 199 to 332 of 336 from GenPept.129 : >gb|AAL20954.1| (AE008790) Propanediol utilization: B12 related [Salmonella typhimurium LT2].


ensembl_gene_id: c4530
symbol: tdcD
gene_biotype: protein_coding
description:
  Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: c4532
symbol: c4532
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 18 to 67 of 83 are 89.99 pct identical to residues 1 to 50 of 94 from GenPept.129 : >gb|AAL20942.1| (AE008790) Propanediol utilization: polyhedral bodies [Salmonella typhimurium LT2].


ensembl_gene_id: c4533
symbol: c4533
gene_biotype: protein_coding
description:
  Putative pduB protein; Residues 33 to 261 of 261 are 63.31 pct identical to residues 6 to 233 of 233 from SwissProt.40 : >sp|P37449|PDUB_SALTY PROPANEDIOL UTILIZATION PROTEIN PDUB.


ensembl_gene_id: c4536
symbol: c4536
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 14 to 198 of 203 are 56.75 pct identical to residues 3 to 187 of 188 from GenPept.129 : >gb|AAL45236.1| (AE009373) conserved hypothetical protein [Agrobacterium tumefaciens str. C58 (U. Washington)].


ensembl_gene_id: c4537
symbol: c4537
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 10 to 849 of 850 are 34.39 pct identical to residues 2 to 765 of 765 from MG1655 : b3951.


ensembl_gene_id: c4539
symbol: c4539
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 294 of 301 are 32.72 pct identical to residues 23 to 340 of 349 from GenPept.129 : >gb|AAG20144.1| (AE005092) Vng1965h [Halobacterium sp. NRC-1].


ensembl_gene_id: c4540
symbol: c4540
gene_biotype: protein_coding
description:
  Putative maturase-related protein; Residues 47 to 179 of 179 are 43.82 pct identical to residues 2 to 163 of 418 from GenPept.129 : >dbj|BAB04330.1| (AP001509) transposase (11) [Bacillus halodurans].


ensembl_gene_id: c4541
symbol: c4541
gene_biotype: protein_coding
description:
  Putative maturase-related protein; Residues 1 to 173 of 173 are 50.85 pct identical to residues 228 to 402 of 490 from GenPept.129 : >gb|AAB68949.1| (U77945) maturase-related protein [Pseudomonas alcaligenes].


ensembl_gene_id: c4545
symbol: c4545
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 12 to 416 of 420 are 34.38 pct identical to residues 1 to 407 of 410 from GenPept.129 : >dbj|BAB80633.1| (AP003188) two-component sensor histidine kinase [Clostridium perfringens].


ensembl_gene_id: c4546
symbol: c4546
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 245 to 342 of 351 are 45.91 pct identical to residues 178 to 275 of 317 from GenPept.129 : >emb|CAD01088.1| (AJ297723) putative transcriptional regulator [Lactobacillus collinoides].


ensembl_gene_id: c4548
symbol: c4548
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 37 to 121 of 213 are 55.29 pct identical to residues 6 to 89 of 94 from GenPept.129 : >gb|AAL94296.1| (AE010523) Ethanolamine utilization protein eutM precursor [Fusobacterium nucleatum subsp. nucleatum ATCC 25586].


ensembl_gene_id: c4549
symbol: c4549
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 11 to 60 of 69 are 47.99 pct identical to residues 7 to 56 of 107 from GenPept.129 : >gb|AAL23089.1| (AE008900) transcriptional activator of superoxide response regulon (AraC/XylS family) [Salmonella typhimurium LT2].


ensembl_gene_id: c4550
symbol: c4550
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 9 to 178 of 189 are 29.31 pct identical to residues 1 to 174 of 212 from GenPept.129 : >gb|AAG06962.1|AE004778_6 (AE004778) probable transcriptional regulator [Pseudomonas aeruginosa].


ensembl_gene_id: c4551
symbol: c4551
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 33 to 328 of 354 are 21.82 pct identical to residues 185 to 490 of 1046 from GenPept.129 : >gb|AAG03815.1|AE004479_10 (AE004479) RND multidrug efflux transporter MexB [Pseudomonas aeruginosa]; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: c4557
symbol: c4557
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 104 to 248 of 254 are 88.27 pct identical to residues 30 to 174 of 179 from GenPept.129 : >gb|AAL67421.1|AF447814_89 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c4558
symbol: c4558
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 243 of 243 are 85.59 pct identical to residues 1 to 243 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli].


ensembl_gene_id: c4564
symbol: c4564
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Residues 1 to 294 of 294 are 94.55 pct identical to residues 1 to 294 of 294 from GenPept.129 : >gb|AAL67395.1|AF447814_63 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c4568
symbol: c4568
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 161 of 260 are 99.37 pct identical to residues 1 to 161 of 260 from GenPept.129 : >gb|AAL67392.1|AF447814_60 (AF447814) putative intergenic-region protein [Escherichia coli].


ensembl_gene_id: c4572
symbol: c4572
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 143 of 148 are 85.50 pct identical to residues 161 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c4577
symbol: c4577
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Residues 79 to 140 of 140 are 98.38 pct identical to residues 4 to 65 of 65 from GenPept.129 : >gb|AAL08480.1| (AF326777) unknown [Shigella flexneri 2a].


ensembl_gene_id: c4580
symbol: c4580
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 3 to 70 of 73 are 41.24 pct identical to residues 148 to 227 of 327 from GenPept.129 : >emb|CAD03240.1| (AL627280) putative DNA-binding protein [Salmonella enterica subsp. enterica serovar Typhi].


ensembl_gene_id: c4582
symbol: yicL
gene_biotype: protein_coding
description:
  Hypothetical transport protein yicL; Escherichia coli K-12 ortholog: b3660; Escherichia coli O157:H7 ortholog: z5146.


ensembl_gene_id: c4583
symbol: nlpA
gene_biotype: protein_coding
description:
  Lipoprotein-28 precursor; Escherichia coli K-12 ortholog: b3661; Escherichia coli O157:H7 ortholog: z5147; Belongs to the nlpA lipoprotein family.


ensembl_gene_id: c4586
symbol: yicM
gene_biotype: protein_coding
description:
  Hypothetical protein yicM; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine; Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.


ensembl_gene_id: c4587
symbol: yicN
gene_biotype: protein_coding
description:
  Hypothetical protein yicN; Escherichia coli K-12 ortholog: b3663; Escherichia coli O157:H7 ortholog: z5152.


ensembl_gene_id: c4588
symbol: yicO
gene_biotype: protein_coding
description:
  Hypothetical protein yicO; Escherichia coli K-12 ortholog: b3664; Escherichia coli O157:H7 ortholog: z5209.


ensembl_gene_id: c4589
symbol: yicP
gene_biotype: protein_coding
description:
  Probable adenine deaminase; Escherichia coli K-12 ortholog: b3665; Escherichia coli O157:H7 ortholog: z5155.


ensembl_gene_id: c4590
symbol: uhpT
gene_biotype: protein_coding
description:
  Hexose phosphate transport protein; Escherichia coli K-12 ortholog: b3666; Escherichia coli O157:H7 ortholog: z5156.


ensembl_gene_id: c4591
symbol: uhpC
gene_biotype: protein_coding
description:
  Regulatory protein uhpC; Escherichia coli K-12 ortholog: b3667; Escherichia coli O157:H7 ortholog: z5157.


ensembl_gene_id: c4592
symbol: uhpB
gene_biotype: protein_coding
description:
  Sensor protein uhpB; Escherichia coli K-12 ortholog: b3668; Escherichia coli O157:H7 ortholog: z5158.


ensembl_gene_id: c4593
symbol: uhpA
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein uhpA; Part of the UhpABC signaling cascade that controls the expression of the hexose phosphate transporter UhpT. Activates the transcription of the uhpT gene. Acts by binding specifically to the uhpT promoter region.


ensembl_gene_id: c4595
symbol: ilvN
gene_biotype: protein_coding
description:
  Acetolactate synthase isozyme I small subunit; Escherichia coli K-12 ortholog: b3670; Escherichia coli O157:H7 ortholog: z5164; Belongs to the acetolactate synthase small subunit family.


ensembl_gene_id: c4596
symbol: ilvB
gene_biotype: protein_coding
description:
  Acetolactate synthase isozyme I large subunit; Escherichia coli K-12 ortholog: b3671; Escherichia coli O157:H7 ortholog: z5165.


ensembl_gene_id: c4597
symbol: emrD
gene_biotype: protein_coding
description:
  Multidrug resistance protein D; Escherichia coli K-12 ortholog: b3673; Escherichia coli O157:H7 ortholog: z5168.


ensembl_gene_id: c4598
symbol: yidF
gene_biotype: protein_coding
description:
  Hypothetical protein yidF; Escherichia coli K-12 ortholog: b3674; Escherichia coli O157:H7 ortholog: z5169.


ensembl_gene_id: c4599
symbol: yidG
gene_biotype: protein_coding
description:
  Hypothetical protein yidG; Escherichia coli K-12 ortholog: b3675; Escherichia coli O157:H7 ortholog: z5170.


ensembl_gene_id: c4600
symbol: yidH
gene_biotype: protein_coding
description:
  Hypothetical protein yidH; Escherichia coli K-12 ortholog: b3676; Escherichia coli O157:H7 ortholog: z5171.


ensembl_gene_id: c4601
symbol: yidJ
gene_biotype: protein_coding
description:
  Putative sulfatase yidJ; Escherichia coli K-12 ortholog: b3678; Escherichia coli O157:H7 ortholog: z5173.


ensembl_gene_id: c4602
symbol: yidK
gene_biotype: protein_coding
description:
  Putative symporter yidK; Escherichia coli K-12 ortholog: b3679; Escherichia coli O157:H7 ortholog: z5174; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: c4603
symbol: yidL
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yidL; Escherichia coli K-12 ortholog: b3680; Escherichia coli O157:H7 ortholog: z5175.


ensembl_gene_id: c4604
symbol: yidE
gene_biotype: protein_coding
description:
  Hypothetical membrane protein yidE; ORFA; Escherichia coli K-12 ortholog: b3685; Escherichia coli O157:H7 ortholog: z5181.


ensembl_gene_id: c4606
symbol: ibpB
gene_biotype: protein_coding
description:
  16 kDa heat shock protein B; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.


ensembl_gene_id: c4607
symbol: ibpA
gene_biotype: protein_coding
description:
  16 kDa heat shock protein A; Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.


ensembl_gene_id: c4608
symbol: yidQ
gene_biotype: protein_coding
description:
  Hypothetical protein yidQ precursor; Escherichia coli K-12 ortholog: b3688; Escherichia coli O157:H7 ortholog: z5184.


ensembl_gene_id: c4609
symbol: yidR
gene_biotype: protein_coding
description:
  Hypothetical protein yidR; Escherichia coli K-12 ortholog: b3689; Escherichia coli O157:H7 ortholog: z5185.


ensembl_gene_id: c4611
symbol: yidS
gene_biotype: protein_coding
description:
  Hypothetical protein yidS precursor; Escherichia coli K-12 ortholog: b3690; Escherichia coli O157:H7 ortholog: z5186; Belongs to the CbrA family.


ensembl_gene_id: c4612
symbol: dgoT
gene_biotype: protein_coding
description:
  D-galactonate transporter; Intake of galactonate into the cell; Belongs to the major facilitator superfamily. Phthalate permease family.


ensembl_gene_id: c4616
symbol: c4616
gene_biotype: protein_coding
description:
  Hypothetical protein; Fusion of Escherichia coli K-12 B3694 and B3695; Residues 1 to 229 of 229 are 99.12 pct identical to residues 1 to 229 of 229 from SwissProt.40 : >sp|P31460|DGOR_ECOLI GALACTONATE OPERON TRANSCRIPTIONAL REPRESSOR.


ensembl_gene_id: c4617
symbol: c4617
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 27 to 143 of 163 are 61.86 pct identical to residues 2 to 119 of 223 from MG1655 : b3696.


ensembl_gene_id: c4618
symbol: c4618
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 42 of 65 are 62.16 pct identical to residues 250 to 286 of 325 from GenPept.129 : >gb|AAG58893.1|AE005600_11 (AE005600) putative replicase [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4619
symbol: yidA
gene_biotype: protein_coding
description:
  Hypothetical protein yidA; Catalyzes the dephosphorylation of different sugar phosphates; Belongs to the HAD-like hydrolase superfamily. Cof family.


ensembl_gene_id: c4620
symbol: yidB
gene_biotype: protein_coding
description:
  Hypothetical protein yidB; Escherichia coli K-12 ortholog: b3698; Escherichia coli O157:H7 ortholog: z5189.


ensembl_gene_id: c4621
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: c4622
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein recF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity).


ensembl_gene_id: c4623
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]


ensembl_gene_id: c4627
symbol: rpmH
gene_biotype: protein_coding
description:
  50S ribosomal protein L34; Escherichia coli K-12 ortholog: b3703; Escherichia coli O157:H7 ortholog: z5194; Belongs to the bacterial ribosomal protein bL34 family.


ensembl_gene_id: c4628
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: c4629
symbol: yidC
gene_biotype: protein_coding
description:
  60 kDa inner-membrane protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: c4630
symbol: thdF
gene_biotype: protein_coding
description:
  Probable tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: c4631
symbol: tnaA
gene_biotype: protein_coding
description:
  Tryptophanase; Escherichia coli K-12 ortholog: b3708; Escherichia coli O157:H7 ortholog: z5203; Belongs to the beta-eliminating lyase family.


ensembl_gene_id: c4632
symbol: tnaB
gene_biotype: protein_coding
description:
  Low affinity tryptophan permease; Escherichia coli K-12 ortholog: b3709; Escherichia coli O157:H7 ortholog: z5204.


ensembl_gene_id: c4633
symbol: yidY
gene_biotype: protein_coding
description:
  Hypothetical transport protein yidY; Confers resistance to chloramphenicol; Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.


ensembl_gene_id: c4635
symbol: yieE
gene_biotype: protein_coding
description:
  Hypothetical protein yieE; Escherichia coli K-12 ortholog: b3712; Escherichia coli O157:H7 ortholog: z5207.


ensembl_gene_id: c4636
symbol: yieF
gene_biotype: protein_coding
description:
  Hypothetical protein yieF; Escherichia coli K-12 ortholog: b3713; Escherichia coli O157:H7 ortholog: z5208.


ensembl_gene_id: c4637
symbol: yieG
gene_biotype: protein_coding
description:
  Hypothetical protein yieG; Escherichia coli K-12 ortholog: b3714; Escherichia coli O157:H7 ortholog: z5209.


ensembl_gene_id: c4638
symbol: yieH
gene_biotype: protein_coding
description:
  Hypothetical protein yieH; Escherichia coli K-12 ortholog: b3715; Escherichia coli O157:H7 ortholog: z5210.


ensembl_gene_id: c4642
symbol: bglH
gene_biotype: protein_coding
description:
  Putative outer membrane protein yieC precursor; May be a sugar porin with a broad carbohydrate specificity. Belongs to the porin LamB (TC 1.B.3) family.


ensembl_gene_id: c4643
symbol: bglB
gene_biotype: protein_coding
description:
  6-phospho-beta-glucosidase bglB; Escherichia coli K-12 ortholog: b3721; Escherichia coli O157:H7 ortholog: z4024; Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: c4644
symbol: bglF
gene_biotype: protein_coding
description:
  PTS system, beta-glucoside-specific IIABC component; EIIABC-Bgl; Escherichia coli K-12 ortholog: b3722.


ensembl_gene_id: c4648
symbol: phoU
gene_biotype: protein_coding
description:
  Phosphate transport system protein phoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. Encoded together with proteins of the phosphate-specific transport (Pst) system in the polycistronic pstSCAB- phoU operon. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR- PhoB transitory complex. Is also part of complex networks important for bacterial virul [...]


ensembl_gene_id: c4649
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate transport ATP-binding protein pstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: c4651
symbol: pstA
gene_biotype: protein_coding
description:
  Phosphate transport system permease protein pstA; Escherichia coli K-12 ortholog: b3726; Escherichia coli O157:H7 ortholog: z5217.


ensembl_gene_id: c4652
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate transport system permease protein pstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: c4653
symbol: pstS
gene_biotype: protein_coding
description:
  Phosphate-binding periplasmic protein precursor; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: c4654
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: c4655
symbol: glmU
gene_biotype: protein_coding
description:
  GlmU protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: c4657
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: c4658
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: c4659
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity).


ensembl_gene_id: c4660
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: c4662
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: c4664
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase B chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: c4665
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: c4666
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: c4667
symbol: atpI
gene_biotype: protein_coding
description:
  ATP synthase protein I; A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex; Belongs to the bacterial AtpI family.


ensembl_gene_id: c4668
symbol: gidB
gene_biotype: protein_coding
description:
  Methyltransferase gidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: c4669
symbol: gidA
gene_biotype: protein_coding
description:
  Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: c4671
symbol: asnC
gene_biotype: protein_coding
description:
  Regulatory protein asnC; Activator of asnA transcription; autogenous regulator of its own transcription; and repressor of the expression of gidA at a post- transcriptional level.


ensembl_gene_id: c4672
symbol: asnA
gene_biotype: protein_coding
description:
  Aspartate--ammonia ligase; Escherichia coli K-12 ortholog: b3744; Escherichia coli O157:H7 ortholog: z5245; Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.


ensembl_gene_id: c4673
symbol: yieM
gene_biotype: protein_coding
description:
  Hypothetical protein yieM; Escherichia coli K-12 ortholog: b3745; Escherichia coli O157:H7 ortholog: z5246.


ensembl_gene_id: c4674
symbol: yieN
gene_biotype: protein_coding
description:
  Hypothetical protein yieN; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family.


ensembl_gene_id: c4675
symbol: kup
gene_biotype: protein_coding
description:
  Kup system potassium uptake protein; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: c4676
symbol: rbsD
gene_biotype: protein_coding
description:
  High affinity ribose transport protein rbsD; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: c4677
symbol: rbsA
gene_biotype: protein_coding
description:
  Ribose transport ATP-binding protein rbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: c4678
symbol: rbsC
gene_biotype: protein_coding
description:
  Ribose transport system permease protein rbsC; Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: c4679
symbol: rbsB
gene_biotype: protein_coding
description:
  D-ribose-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b3751; Escherichia coli O157:H7 ortholog: z5252.


ensembl_gene_id: c4680
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: c4681
symbol: rbsR
gene_biotype: protein_coding
description:
  Ribose operon repressor; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon (By similarity).


ensembl_gene_id: c4682
symbol: yieO
gene_biotype: protein_coding
description:
  Hypothetical transport protein yieO; Escherichia coli K-12 ortholog: b3754; Escherichia coli O157:H7 ortholog: z5255; Belongs to the major facilitator superfamily.


ensembl_gene_id: c4683
symbol: yieP
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yieP; Escherichia coli K-12 ortholog: b3755; Escherichia coli O157:H7 ortholog: z5258.


ensembl_gene_id: c4685
symbol: yifA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.


ensembl_gene_id: c4686
symbol: yifE
gene_biotype: protein_coding
description:
  Protein yifE; Escherichia coli K-12 ortholog: b3764; Escherichia coli O157:H7 ortholog: z5276; Belongs to the UPF0438 family.


ensembl_gene_id: c4687
symbol: yifB
gene_biotype: protein_coding
description:
  Hypothetical protein yifB; ORF III; Escherichia coli K-12 ortholog: b3765; Escherichia coli O157:H7 ortholog: z5277; bifunctional.


ensembl_gene_id: c4688
symbol: c4688
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 95 of 109 are 100.00 pct identical to residues 1 to 95 of 516 from GenPept.129 : >gb|AAG58961.1|AE005608_2 (AE005608) putative 2-component regulator [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4691
symbol: ilvM
gene_biotype: protein_coding
description:
  Acetolactate synthase isozyme II small subunit; Escherichia coli K-12 ortholog: b3769; Escherichia coli O157:H7 ortholog: z5280.


ensembl_gene_id: c4693
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase; Escherichia coli K-12 ortholog: b3771; Escherichia coli O157:H7 ortholog: z5282.


ensembl_gene_id: c4694
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: c4695
symbol: ilvY
gene_biotype: protein_coding
description:
  Transcriptional activator protein ilvY; Escherichia coli K-12 ortholog: b3773; Escherichia coli O157:H7 ortholog: z5284; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: c4696
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: c4697
symbol: ppiC
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase C; PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates (By similarity).


ensembl_gene_id: c4698
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: c4699
symbol: gppA
gene_biotype: protein_coding
description:
  Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.


ensembl_gene_id: c4700
symbol: rhlB
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase rhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: c4701
symbol: trxA
gene_biotype: protein_coding
description:
  Thioredoxin 1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family.


ensembl_gene_id: c4702
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: c4703
symbol: c4703
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 41 of 41 are 97.56 pct identical to residues 1 to 41 of 72 from GenPept.129 : >gb|AAG58978.1|AE005610_2 (AE005610) Z5294 gene product [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4704
symbol: rfe
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).


ensembl_gene_id: c4705
symbol: wzzE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein wzzE; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.


ensembl_gene_id: c4706
symbol: wecB
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.


ensembl_gene_id: c4707
symbol: wecC
gene_biotype: protein_coding
description:
  UDP-N-acetyl-D-mannosamine dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.


ensembl_gene_id: c4708
symbol: rffG
gene_biotype: protein_coding
description:
  dTDP-glucose 4,6-dehydratase; Escherichia coli K-12 ortholog: b3788; Escherichia coli O157:H7 ortholog: z5299; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: c4709
symbol: rffH
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: c4710
symbol: wecD
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein rffC; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.


ensembl_gene_id: c4711
symbol: wecE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein rffA; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: c4713
symbol: wzxE
gene_biotype: protein_coding
description:
  WzxE protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.


ensembl_gene_id: c4714
symbol: wecF-2
gene_biotype: protein_coding
description:
  4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.


ensembl_gene_id: c4715
symbol: wecF
gene_biotype: protein_coding
description:
  Putative ECA polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.


ensembl_gene_id: c4716
symbol: wecG
gene_biotype: protein_coding
description:
  Probable UDP-N-acetyl-D-mannosaminuronic acid transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.


ensembl_gene_id: c4717
symbol: yifK
gene_biotype: protein_coding
description:
  Probable transport protein yifK; Escherichia coli K-12 ortholog: b3795; Escherichia coli O157:H7 ortholog: z5307.


ensembl_gene_id: c4718
symbol: aslB
gene_biotype: protein_coding
description:
  Putative arylsulfatase Regulatory protein; Escherichia coli K-12 ortholog: b3800; Escherichia coli O157:H7 ortholog: z5313.


ensembl_gene_id: c4722
symbol: hemX
gene_biotype: protein_coding
description:
  Putative uroporphyrin-III C-methyltransferase; Escherichia coli K-12 ortholog: b3803; Escherichia coli O157:H7 ortholog: z5317.


ensembl_gene_id: c4723
symbol: hemD
gene_biotype: protein_coding
description:
  Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: c4724
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: c4725
symbol: cyaA
gene_biotype: protein_coding
description:
  Adenylate cyclase; Escherichia coli K-12 ortholog: b3806; Escherichia coli O157:H7 ortholog: z5322; Belongs to the adenylyl cyclase class-1 family.


ensembl_gene_id: c4726
symbol: cyaY
gene_biotype: protein_coding
description:
  CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: c4727
symbol: c4727
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 254 to 430 of 439 are 44.06 pct identical to residues 493 to 667 of 669 from GenPept.129 : >emb|CAD09375.1| (AL627279) possible exported protein [Salmonella enterica subsp. enterica serovar Typhi].


ensembl_gene_id: c4728
symbol: c4728
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 11 to 499 of 499 are 62.62 pct identical to residues 1 to 495 of 669 from GenPept.129 : >emb|CAD09375.1| (AL627279) possible exported protein [Salmonella enterica subsp. enterica serovar Typhi].


ensembl_gene_id: c4730
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: c4731
symbol: yigA
gene_biotype: protein_coding
description:
  Hypothetical protein yigA; Escherichia coli K-12 ortholog: b3810; Escherichia coli O157:H7 ortholog: z5327.


ensembl_gene_id: c4732
symbol: xerC
gene_biotype: protein_coding
description:
  Integrase/recombinase xerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges  [...]


ensembl_gene_id: c4733
symbol: yigB
gene_biotype: protein_coding
description:
  Hypothetical protein yigB; Escherichia coli K-12 ortholog: b3812; Escherichia coli O157:H7 ortholog: z5329.


ensembl_gene_id: c4737
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein corA; Mediates influx of magnesium ions. Can also mediate cobalt and manganese uptake (By similarity). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high (By similarity). Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: c4741
symbol: yigI
gene_biotype: protein_coding
description:
  Hypothetical protein yigI; Escherichia coli K-12 ortholog: b3820; Escherichia coli O157:H7 ortholog: z5341.


ensembl_gene_id: c4742
symbol: pldA
gene_biotype: protein_coding
description:
  Phospholipase A1 precursor; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: c4744
symbol: recQ
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase recQ; Escherichia coli K-12 ortholog: b3822; Escherichia coli O157:H7 ortholog: z5343.


ensembl_gene_id: c4745
symbol: c4745
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 206 of 206 are 99.02 pct identical to residues 1 to 206 of 206 from SwissProt.40 : >sp|P27846|RHTC_ECOLI Threonine efflux protein.


ensembl_gene_id: c4746
symbol: yigK
gene_biotype: protein_coding
description:
  Homoserine/homoserine lactone efflux protein; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family.


ensembl_gene_id: c4747
symbol: pldB
gene_biotype: protein_coding
description:
  Lysophospholipase L2; Escherichia coli K-12 ortholog: b3825; Escherichia coli O157:H7 ortholog: z5346.


ensembl_gene_id: c4749
symbol: yigM
gene_biotype: protein_coding
description:
  Hypothetical membrane protein yigM; Escherichia coli K-12 ortholog: b3827; Escherichia coli O157:H7 ortholog: z5348.


ensembl_gene_id: c4750
symbol: metR
gene_biotype: protein_coding
description:
  Transcriptional activator protein metR; Escherichia coli K-12 ortholog: b3828; Escherichia coli O157:H7 ortholog: z5349; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: c4751
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: c4753
symbol: c4753
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 11 to 77 of 86 are 34.32 pct identical to residues 32 to 98 of 106 from GenPept.129 : >emb|CAD16922.1| (AL646075) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum].


ensembl_gene_id: c4754
symbol: c4754
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 73 of 85 are 33.82 pct identical to residues 31 to 98 of 106 from GenPept.129 : >emb|CAD16922.1| (AL646075) CONSERVED HYPOTHETICAL PROTEIN [Ralstonia solanacearum].


ensembl_gene_id: c4755
symbol: c4755
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 31 to 227 of 229 are 44.17 pct identical to residues 188 to 384 of 386 from GenPept.129 : >emb|CAD16923.1| (AL646075) PROBABLE TRANSMEMBRANE PROTEIN [Ralstonia solanacearum].


ensembl_gene_id: c4757
symbol: c4757
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 5 to 189 of 189 are 38.37 pct identical to residues 1 to 184 of 184 from GenPept.129 : >emb|CAD22377.1| (AX343668) unnamed protein product [Brevibacillus brevis].


ensembl_gene_id: c4758
symbol: c4758
gene_biotype: protein_coding
description:
  PTS system, glucose-specific IIBC component; EIIBC-Glc; Escherichia coli K-12 ortholog: b1101; Escherichia coli O157:H7 ortholog: z1740.


ensembl_gene_id: c4760
symbol: c4760
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 10 to 262 of 281 are 28.34 pct identical to residues 15 to 268 of 287 from GenPept.129 : >dbj|BAB06394.1| (AP001516) transcriptional regulator (RpiR family) [Bacillus halodurans].


ensembl_gene_id: c4761
symbol: c4761
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 4 to 297 of 301 are 34.35 pct identical to residues 3 to 296 of 310 from MG1655 : b1659; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: c4762
symbol: c4762
gene_biotype: protein_coding
description:
  Putative permease; Residues 14 to 395 of 407 are 28.42 pct identical to residues 27 to 419 of 445 from GenPept.129 : >dbj|BAB05601.1| (AP001513) cytosine permease [Bacillus halodurans].


ensembl_gene_id: c4763
symbol: c4763
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 122 of 129 are 38.33 pct identical to residues 474 to 593 of 619 from GenPept.129 : >dbj|BAB53245.1| (AP003010) glutamyl-tRNA(Gln) amidotransferase subunit A [Mesorhizobium loti].


ensembl_gene_id: c4765
symbol: c4765
gene_biotype: protein_coding
description:
  Hypothetical protein yahG; Escherichia coli K-12 ortholog: b0321; Escherichia coli O157:H7 ortholog: z0410.


ensembl_gene_id: c4768
symbol: c4768
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 24 to 278 of 286 are 25.37 pct identical to residues 18 to 274 of 287 from GenPept.129 : >gb|AAG54663.1|AE005210_7 (AE005210) orf, hypothetical protein [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c4769
symbol: c4769
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 197 of 199 are 56.78 pct identical to residues 34 to 232 of 233 from GenPept.129 : >dbj|BAB53241.1| (AP003010) hypothetical protein [Mesorhizobium loti].


ensembl_gene_id: c4773
symbol: udp
gene_biotype: protein_coding
description:
  Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: c4774
symbol: c4774
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 19 to 496 of 496 are 46.99 pct identical to residues 16 to 493 of 504 from GenPept.129 : >dbj|BAB05728.1| (AP001514) BH2009; unknown conserved protein in others [Bacillus halodurans].


ensembl_gene_id: c4775
symbol: c4775
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 52 to 165 of 169 are 31.66 pct identical to residues 28 to 144 of 147 from GenPept.129 : >gb|AAL94188.1| (AE010513) unknown [Fusobacterium nucleatum subsp. nucleatum ATCC 25586].


ensembl_gene_id: c4776
symbol: c4776
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 31 to 322 of 324 are 33.44 pct identical to residues 15 to 307 of 308 from GenPept.129 : >gb|AAL94187.1| (AE010513) RecA protein [Fusobacterium nucleatum subsp. nucleatum ATCC 25586].


ensembl_gene_id: c4777
symbol: c4777
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 9 to 203 of 209 are 41.08 pct identical to residues 6 to 200 of 587 from MG1655 : b3692.


ensembl_gene_id: c4778
symbol: c4778
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 7 to 319 of 334 are 34.38 pct identical to residues 5 to 289 of 292 from MG1655 : b3693.


ensembl_gene_id: c4779
symbol: c4779
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Residues 40 to 273 of 284 are 32.36 pct identical to residues 2 to 242 of 254 from GenPept.129 : >emb|CAC40602.1| (AL591857) putative IclR-family transcriptional regulatory protein [Streptomyces coelicolor].


ensembl_gene_id: c4781
symbol: yigN
gene_biotype: protein_coding
description:
  DNA recombination protein rmuC; Escherichia coli K-12 ortholog: b3832; Escherichia coli O157:H7 ortholog: z5354.


ensembl_gene_id: c4782
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: c4783
symbol: yigP
gene_biotype: protein_coding
description:
  Hypothetical protein yigP; Escherichia coli K-12 ortholog: b3834; Escherichia coli O157:H7 ortholog: z5356.


ensembl_gene_id: c4784
symbol: yigR
gene_biotype: protein_coding
description:
  Probable ubiquinone biosynthesis protein ubiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: c4785
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein tatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: c4786
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein tatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: c4787
symbol: yigU
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein tatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: c4788
symbol: yigW
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.


ensembl_gene_id: c4789
symbol: rfaH
gene_biotype: protein_coding
description:
  Transcriptional activator rfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains (By similarity). Contributes to intestinal colonization via [...]


ensembl_gene_id: c4790
symbol: yigC
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: c4791
symbol: ubiB
gene_biotype: protein_coding
description:
  NAD(P)H-flavin reductase; Catalyzes the reduction of soluble flavins by reduced pyridine nucleotides; Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.


ensembl_gene_id: c4792
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity).


ensembl_gene_id: c4793
symbol: fadB
gene_biotype: protein_coding
description:
  Fatty oxidation complex alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: c4795
symbol: yigZ
gene_biotype: protein_coding
description:
  Hypothetical protein yigZ; Escherichia coli K-12 ortholog: b3848; Escherichia coli O157:H7 ortholog: z5370.


ensembl_gene_id: c4796
symbol: trkH
gene_biotype: protein_coding
description:
  Trk system potassium uptake protein trkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: c4797
symbol: hemG
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX using menaquinone as electron acceptor.


ensembl_gene_id: c4800
symbol: mobB
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein B; Escherichia coli K-12 ortholog: b3856; Escherichia coli O157:H7 ortholog: z5388.


ensembl_gene_id: c4801
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: c4802
symbol: yihD
gene_biotype: protein_coding
description:
  Protein yihD; Escherichia coli K-12 ortholog: b3858; Escherichia coli O157:H7 ortholog: z5390; To H.influenzae HI_0845.


ensembl_gene_id: c4803
symbol: yihE
gene_biotype: protein_coding
description:
  Hypothetical protein yihE; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: c4804
symbol: dsbA
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein dsbA precursor; Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. It is required for pilus biogenesis (By similarity). Belongs to the thioredoxin family. DsbA subfamily.


ensembl_gene_id: c4806
symbol: yihF
gene_biotype: protein_coding
description:
  Hypothetical protein yihF; Escherichia coli K-12 ortholog: b3861; Escherichia coli O157:H7 ortholog: z5393.


ensembl_gene_id: c4807
symbol: yihG
gene_biotype: protein_coding
description:
  Hypothetical protein yihG; Escherichia coli K-12 ortholog: b3862; Escherichia coli O157:H7 ortholog: z5394.


ensembl_gene_id: c4812
symbol: yihA
gene_biotype: protein_coding
description:
  Probable GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: c4815
symbol: yihI
gene_biotype: protein_coding
description:
  Hypothetical protein yihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: c4816
symbol: hemN
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase; Escherichia coli K-12 ortholog: b3867; Escherichia coli O157:H7 ortholog: z5403; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: c4817
symbol: glnG
gene_biotype: protein_coding
description:
  Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: c4818
symbol: glnL
gene_biotype: protein_coding
description:
  Nitrogen regulation protein NR(II); Escherichia coli K-12 ortholog: b3869; Escherichia coli O157:H7 ortholog: z5405.


ensembl_gene_id: c4819
symbol: glnA
gene_biotype: protein_coding
description:
  Glutamine synthetase; Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia; Belongs to the glutamine synthetase family.


ensembl_gene_id: c4820
symbol: yihK
gene_biotype: protein_coding
description:
  GTP-binding protein typA/BipA; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.


ensembl_gene_id: c4821
symbol: yihL
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yihL; Escherichia coli K-12 ortholog: b3872; Escherichia coli O157:H7 ortholog: z5408.


ensembl_gene_id: c4822
symbol: yihM
gene_biotype: protein_coding
description:
  Hypothetical protein yihM; Escherichia coli K-12 ortholog: b3873; Escherichia coli O157:H7 ortholog: z5409.


ensembl_gene_id: c4823
symbol: yihN
gene_biotype: protein_coding
description:
  Hypothetical protein yihN; Escherichia coli K-12 ortholog: b3874; Escherichia coli O157:H7 ortholog: z5410.


ensembl_gene_id: c4824
symbol: yihW
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yihW; Escherichia coli K-12 ortholog: b3884; Escherichia coli O157:H7 ortholog: z5422.


ensembl_gene_id: c4825
symbol: yihV
gene_biotype: protein_coding
description:
  Hypothetical sugar kinase yihV; Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6-deoxy-6- sulfo-D-fructose 1-phosphate (SFP); Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: c4826
symbol: yihU
gene_biotype: protein_coding
description:
  Hypothetical oxidoreductase yihU; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily.


ensembl_gene_id: c4827
symbol: yihT
gene_biotype: protein_coding
description:
  Hypothetical protein yihT; Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA). Belongs to the aldolase LacD family.


ensembl_gene_id: c4828
symbol: c4828
gene_biotype: protein_coding
description:
  Putative dehydrogenase; Zinc binding; Residues 29 to 330 of 336 are 33.64 pct identical to residues 45 to 365 of 368 from GenPept.129 : >gb|AAK71492.1| (AY037946) sorbitol dehydrogenase [Prunus cerasus].


ensembl_gene_id: c4829
symbol: c4829
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 30 to 455 of 477 are 22.60 pct identical to residues 62 to 476 of 486 from GenPept.129 : >emb|CAC11594.1| (AL445064) sugar transport protein related protein [Thermoplasma acidophilum].


ensembl_gene_id: c4831
symbol: c4831
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 46 to 310 of 314 are 43.39 pct identical to residues 4 to 259 of 262 from GenPept.129 : >emb|CAB42038.1| (AL049754) hypothetical protein [Streptomyces coelicolor A3(2)].


ensembl_gene_id: c4832
symbol: yihX
gene_biotype: protein_coding
description:
  Hypothetical protein yihX; Escherichia coli K-12 ortholog: b3885; Escherichia coli O157:H7 ortholog: z5424.


ensembl_gene_id: c4834
symbol: yihZ
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: c4835
symbol: yiiD
gene_biotype: protein_coding
description:
  Hypothetical protein yiiD; Escherichia coli K-12 ortholog: b3888; Escherichia coli O157:H7 ortholog: z5427.


ensembl_gene_id: c4836
symbol: c4836
gene_biotype: protein_coding
description:
  Putative lipase; Residues 5 to 303 of 306 are 74.91 pct identical to residues 1 to 299 of 309 from GenPept.129 : >emb|CAD09594.1| (AL627279) putative lipase [Salmonella enterica subsp. enterica serovar Typhi].


ensembl_gene_id: c4837
symbol: c4837
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 2 to 103 of 103 are 41.17 pct identical to residues 4 to 105 of 110 from GenPept.129 : >gb|AAF96372.1| (AE004379) hypothetical protein [Vibrio cholerae].


ensembl_gene_id: c4838
symbol: c4838
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 13 to 94 of 96 are 87.80 pct identical to residues 1 to 82 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) putative bacterial regulatory protein, merR family [Salmonella typhimurium LT2].


ensembl_gene_id: c4840
symbol: yiiE
gene_biotype: protein_coding
description:
  Hypothetical protein yiiE; Escherichia coli K-12 ortholog: b3889; Escherichia coli O157:H7 ortholog: z5431; Belongs to the YiiE family.


ensembl_gene_id: c4842
symbol: fdoI
gene_biotype: protein_coding
description:
  Formate dehydrogenase; Allows to use formate as major electron donor during aerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase (By similarity).


ensembl_gene_id: c4843
symbol: fdoH
gene_biotype: protein_coding
description:
  Formate dehydrogenase-O beta subunit; Allows to use formate as major electron donor during aerobic respiration. The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit (By similarity).


ensembl_gene_id: c4847
symbol: fdhD
gene_biotype: protein_coding
description:
  FdhD protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: c4848
symbol: c4848
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 1 to 163 of 184 are 74.51 pct identical to residues 139 to 346 of 351 from MG1655 : b3896.


ensembl_gene_id: c4851
symbol: rhaD
gene_biotype: protein_coding
description:
  Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.


ensembl_gene_id: c4852
symbol: rhaA
gene_biotype: protein_coding
description:
  L-rhamnose isomerase; Escherichia coli K-12 ortholog: b3903; Escherichia coli O157:H7 ortholog: z5447.


ensembl_gene_id: c4853
symbol: rhaB
gene_biotype: protein_coding
description:
  Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.


ensembl_gene_id: c4856
symbol: rhaR
gene_biotype: protein_coding
description:
  L-rhamnose operon transcriptional activator rhaR; Activates expression of the rhaSR operon in response to L- rhamnose.


ensembl_gene_id: c4857
symbol: rhaT
gene_biotype: protein_coding
description:
  L-rhamnose-proton symport; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.


ensembl_gene_id: c4859
symbol: sodA
gene_biotype: protein_coding
description:
  Superoxide dismutase (Mn); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: c4861
symbol: kdgT
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity); Belongs to the KdgT transporter family.


ensembl_gene_id: c4862
symbol: yiiM
gene_biotype: protein_coding
description:
  Hypothetical protein yiiM; Escherichia coli K-12 ortholog: b3910; Escherichia coli O157:H7 ortholog: z5455.


ensembl_gene_id: c4863
symbol: cpxA
gene_biotype: protein_coding
description:
  Sensor protein cpxA; This protein is involved in several diverse cellular processes, such as the functioning of acetohydroxyacid synthetase I, in the biosynthesis of isoleucine and valine, the TraJ protein activation activity for tra gene expression in F plasmid, and the synthesis, translocation, or stability of cell envelope proteins. Activates CpxR by phosphorylation (By similarity).


ensembl_gene_id: c4864
symbol: cpxR
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein cpxR; Escherichia coli K-12 ortholog: b3912; Escherichia coli O157:H7 ortholog: z5457.


ensembl_gene_id: c4865
symbol: cpxP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Acts as an accessory protein in the Cpx two-component envelope stress response system. Binds the periplasmic domain of sensor histidine kinase CpxA, inhibiting induction of the envelope stress response in the absence of inducer. Aids in combating extracytoplasmic protein-mediated toxicity.


ensembl_gene_id: c4866
symbol: yiiP
gene_biotype: protein_coding
description:
  Hypothetical protein yiiP; Iron-efflux transporter responsible for iron detoxification. Also able to transport Zn(2+) in a proton-dependent manner (By similarity).


ensembl_gene_id: c4867
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase isozyme I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: c4869
symbol: sbp
gene_biotype: protein_coding
description:
  Sulfate-binding protein precursor; Sulfate starvation-induced protein 2; Escherichia coli K-12 ortholog: b3917; Escherichia coli O157:H7 ortholog: z5462.


ensembl_gene_id: c4870
symbol: cdh
gene_biotype: protein_coding
description:
  CDP-diacylglycerol pyrophosphatase; Escherichia coli K-12 ortholog: b3918; Escherichia coli O157:H7 ortholog: z5463.


ensembl_gene_id: c4871
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: c4872
symbol: yiiQ
gene_biotype: protein_coding
description:
  Hypothetical protein yiiQ precursor; Escherichia coli K-12 ortholog: b3920; Escherichia coli O157:H7 ortholog: z5465.


ensembl_gene_id: c4873
symbol: yiiR
gene_biotype: protein_coding
description:
  Hypothetical protein yiiR; Escherichia coli K-12 ortholog: b3921; Escherichia coli O157:H7 ortholog: z5466.


ensembl_gene_id: c4874
symbol: yiiS
gene_biotype: protein_coding
description:
  Hypothetical protein yiiS; Escherichia coli K-12 ortholog: b3922; Escherichia coli O157:H7 ortholog: z5467.


ensembl_gene_id: c4875
symbol: yiiT
gene_biotype: protein_coding
description:
  Hypothetical protein yiiT; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.


ensembl_gene_id: c4876
symbol: fpr
gene_biotype: protein_coding
description:
  Ferredoxin--NADP reductase; Escherichia coli K-12 ortholog: b3924; Escherichia coli O157:H7 ortholog: z5469.


ensembl_gene_id: c4877
symbol: glpX
gene_biotype: protein_coding
description:
  Protein glpX; Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate; Belongs to the FBPase class 2 family.


ensembl_gene_id: c4878
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: c4879
symbol: glpF
gene_biotype: protein_coding
description:
  Glycerol uptake facilitator protein; Transporter of glycerol across the cytoplasmic membrane, with limited permeability to water and small uncharged compounds such as polyols.


ensembl_gene_id: c4880
symbol: yiiU
gene_biotype: protein_coding
description:
  Hypothetical protein yiiU; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: c4881
symbol: menG
gene_biotype: protein_coding
description:
  S-adenosylmethionine:2-demethylmenaquinone methyltransferase; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: c4883
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: c4884
symbol: hslU
gene_biotype: protein_coding
description:
  ATP-dependent hsl protease ATP-binding subunit hslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: c4885
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease hslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. Belongs to the peptidase T1B family. HslV subfamily.


ensembl_gene_id: c4886
symbol: ftsN
gene_biotype: protein_coding
description:
  Cell division protein ftsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.


ensembl_gene_id: c4887
symbol: cytR
gene_biotype: protein_coding
description:
  Transcriptional repressor cytR; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors (By similarity).


ensembl_gene_id: c4888
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: c4890
symbol: yiiX
gene_biotype: protein_coding
description:
  Hypothetical protein yiiX precursor; Escherichia coli K-12 ortholog: b3937; Escherichia coli O157:H7 ortholog: z5492.


ensembl_gene_id: c4891
symbol: metJ
gene_biotype: protein_coding
description:
  Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.


ensembl_gene_id: c4892
symbol: metB
gene_biotype: protein_coding
description:
  Cystathionine gamma-synthase; Escherichia coli K-12 ortholog: b3939; Escherichia coli O157:H7 ortholog: z5494.


ensembl_gene_id: c4893
symbol: metL
gene_biotype: protein_coding
description:
  AKII-HDII protein; Bifunctional; Escherichia coli K-12 ortholog: b3940; Escherichia coli O157:H7 ortholog: z5495; bifunctional; Aspartokinase II; Homoserine dehydrogenase II; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: c4895
symbol: c4895
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 10 to 537 of 541 are 64.65 pct identical to residues 5 to 513 of 518 from GenPept.129 : >gb|AAL22944.1| (AE008891) putative 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Salmonella typhimurium LT2]; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: c4896
symbol: c4896
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 3 to 517 of 517 are 58.95 pct identical to residues 7 to 523 of 523 from GenPept.129 : >gb|AAL18997.1| (AE008694) putative 5'-nucleotidase [Salmonella typhimurium LT2]; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: c4897
symbol: c4897
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 367 of 374 are 61.68 pct identical to residues 1 to 368 of 374 from GenPept.129 : >gb|AAL22943.1| (AE008891) putative cytoplasmic protein [Salmonella typhimurium LT2].


ensembl_gene_id: c4898
symbol: c4898
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 3 to 519 of 519 are 91.87 pct identical to residues 1 to 517 of 518 from GenPept.129 : >gb|AAL22944.1| (AE008891) putative 5'-nucleotidase/2',3'-cyclic phosphodiesterase or related esterase [Salmonella typhimurium LT2]; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: c4899
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Escherichia coli K-12 ortholog: b3941; Escherichia coli O157:H7 ortholog: z5496; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: c4900
symbol: katG
gene_biotype: protein_coding
description:
  Peroxidase/catalase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: c4901
symbol: yijE
gene_biotype: protein_coding
description:
  Hypothetical transport protein yijE; Involved in response to cystine. Belongs to the EamA transporter family.


ensembl_gene_id: c4902
symbol: yijF
gene_biotype: protein_coding
description:
  Hypothetical protein yijF precursor; Escherichia coli K-12 ortholog: b3944; Escherichia coli O157:H7 ortholog: z5499.


ensembl_gene_id: c4904
symbol: gldA
gene_biotype: protein_coding
description:
  Glycerol dehydrogenase; Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions (By similarity). Belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: c4905
symbol: talC
gene_biotype: protein_coding
description:
  Fructose-6-phosphate aldolase 2; Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction; Belongs to the transaldolase family. Type 3A subfamily.


ensembl_gene_id: c4906
symbol: ptsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase ptsA; Escherichia coli K-12 ortholog: b3947; Escherichia coli O157:H7 ortholog: z5502.


ensembl_gene_id: c4907
symbol: frwC
gene_biotype: protein_coding
description:
  PTS system, fructose-like-2 IIC component; Phosphotransferase enzyme II, C component; Escherichia coli K-12 ortholog: b3949; Escherichia coli O157:H7 ortholog: z5504.


ensembl_gene_id: c4908
symbol: frwB
gene_biotype: protein_coding
description:
  PTS system, fructose-like-2 IIB component 1; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FrwABC PTS system is involved in fructose transport.


ensembl_gene_id: c4910
symbol: pflD
gene_biotype: protein_coding
description:
  Formate acetyltransferase 2; Escherichia coli K-12 ortholog: b3951; Escherichia coli O157:H7 ortholog: z5507.


ensembl_gene_id: c4911
symbol: pflC
gene_biotype: protein_coding
description:
  Pyruvate formate-lyase 2 activating enzyme; Escherichia coli K-12 ortholog: b3952; Escherichia coli O157:H7 ortholog: z5508.


ensembl_gene_id: c4912
symbol: frwD
gene_biotype: protein_coding
description:
  PTS system, fructose-like-2 IIB component 2; Phosphotransferase enzyme II, B component; Escherichia coli K-12 ortholog: b3953; Escherichia coli O157:H7 ortholog: z5509.


ensembl_gene_id: c4913
symbol: yijO
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yijO; Escherichia coli K-12 ortholog: b3954; Escherichia coli O157:H7 ortholog: z5512.


ensembl_gene_id: c4915
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.


ensembl_gene_id: c4916
symbol: argE
gene_biotype: protein_coding
description:
  Acetylornithine deacetylase; Displays a broad specificity and can also deacylate substrates such as acetylarginine, acetylhistidine or acetylglutamate semialdehyde.


ensembl_gene_id: c4917
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: c4919
symbol: argH
gene_biotype: protein_coding
description:
  Argininosuccinate lyase; Escherichia coli K-12 ortholog: b3960; Escherichia coli O157:H7 ortholog: z5518.


ensembl_gene_id: c4921
symbol: yjiZ
gene_biotype: protein_coding
description:
  Hypothetical transport protein yjjL; Escherichia coli K-12 ortholog: b4356; Escherichia coli O157:H7 ortholog: z5956.


ensembl_gene_id: c4922
symbol: oxyR
gene_biotype: protein_coding
description:
  Hydrogen peroxide-inducible genes activator; Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstream of its own coding sequence. OxyR is inactivated by reduction of its essential disulfide bond by the product of GrxA, itself positively regulated by OxyR. Has also a positive regulatory effect on the production of surface proteins that control the colony morphology and auto- aggregation ab [...]


ensembl_gene_id: c4923
symbol: udhA
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.


ensembl_gene_id: c4926
symbol: yijC
gene_biotype: protein_coding
description:
  Hypothetical protein yijC; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.


ensembl_gene_id: c4927
symbol: yijD
gene_biotype: protein_coding
description:
  Hypothetical protein yijD; Escherichia coli K-12 ortholog: b3964; Escherichia coli O157:H7 ortholog: z5525.


ensembl_gene_id: c4928
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (Uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: c4929
symbol: btuB
gene_biotype: protein_coding
description:
  Vitamin B12 receptor precursor; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.


ensembl_gene_id: c4932
symbol: birA
gene_biotype: protein_coding
description:
  BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: c4933
symbol: coaA
gene_biotype: protein_coding
description:
  Pantothenate kinase; Escherichia coli K-12 ortholog: b3974; Escherichia coli O157:H7 ortholog: z5545.


ensembl_gene_id: c4934
symbol: c4934
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 53 of 53 are 96.22 pct identical to residues 1 to 53 of 53 from SwissProt.40 : >sp|P15045|YZRS_ECOLI VERY HYPOTHETICAL 6.2 KD PROTEIN IN RTS 5'REGION.


ensembl_gene_id: c4935
symbol: tufB
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: c4936
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase secE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: c4937
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination [...]


ensembl_gene_id: c4939
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: c4940
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: c4941
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA (By similarity); Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: c4943
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: c4944
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: c4945
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: c4946
symbol: thiH
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein thiH; Escherichia coli K-12 ortholog: b3990; Escherichia coli O157:H7 ortholog: z5564.


ensembl_gene_id: c4947
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein thiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: c4949
symbol: thiF
gene_biotype: protein_coding
description:
  Adenylyltransferase thiF; Escherichia coli K-12 ortholog: b3992; Escherichia coli O157:H7 ortholog: z5567.


ensembl_gene_id: c4950
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: c4951
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: c4952
symbol: yjaE
gene_biotype: protein_coding
description:
  Regulator of sigma D; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.


ensembl_gene_id: c4953
symbol: yjaD
gene_biotype: protein_coding
description:
  NADH pyrophosphatase; Escherichia coli K-12 ortholog: b3996; Escherichia coli O157:H7 ortholog: z5571.


ensembl_gene_id: c4954
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: c4955
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: c4956
symbol: yjaG
gene_biotype: protein_coding
description:
  Hypothetical protein yjaG; Escherichia coli K-12 ortholog: b3999; Escherichia coli O157:H7 ortholog: z5575.


ensembl_gene_id: c4957
symbol: hupA
gene_biotype: protein_coding
description:
  DNA-binding protein HU-alpha; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: c4958
symbol: yjaH
gene_biotype: protein_coding
description:
  Hypothetical protein yjaH; Escherichia coli K-12 ortholog: b4001; Escherichia coli O157:H7 ortholog: z5577.


ensembl_gene_id: c4959
symbol: yjaI
gene_biotype: protein_coding
description:
  Zinc resistance-associated protein precursor; Binds zinc. Could be an important component of the zinc- balancing mechanism (By similarity); Belongs to the ZraP family.


ensembl_gene_id: c4961
symbol: hydH
gene_biotype: protein_coding
description:
  Sensor protein zraS; Escherichia coli K-12 ortholog: b4003; Escherichia coli O157:H7 ortholog: z5579.


ensembl_gene_id: c4962
symbol: hydG
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein zraR; Escherichia coli K-12 ortholog: b4004; Escherichia coli O157:H7 ortholog: z5580.


ensembl_gene_id: c4963
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylamine--glycine ligase; Escherichia coli K-12 ortholog: b4005; Escherichia coli O157:H7 ortholog: z5582; Belongs to the GARS family.


ensembl_gene_id: c4964
symbol: purH
gene_biotype: protein_coding
description:
  Purine biosynthesis protein PurH; Bifunctional; Escherichia coli K-12 ortholog: b4006; Escherichia coli O157:H7 ortholog: z5583; bifunctional; Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase.


ensembl_gene_id: c4969
symbol: yjaB
gene_biotype: protein_coding
description:
  Hypothetical acetyltransferase yjaB; Escherichia coli K-12 ortholog: b4012; Escherichia coli O157:H7 ortholog: z5598.


ensembl_gene_id: c4970
symbol: metA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: c4971
symbol: aceB
gene_biotype: protein_coding
description:
  Malate synthase A; Escherichia coli K-12 ortholog: b4014; Escherichia coli O157:H7 ortholog: z5600; Belongs to the malate synthase family.


ensembl_gene_id: c4972
symbol: aceA
gene_biotype: protein_coding
description:
  Isocitrate lyase; Involved in the metabolic adaptation in response to environmental changes. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.


ensembl_gene_id: c4973
symbol: c4973
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 3 to 46 of 48 are 61.70 pct identical to residues 21 to 67 of 103 from GenPept.129 : >gb|AAB18079.1| (U73857) hypothetical protein [Escherichia coli].


ensembl_gene_id: c4974
symbol: aceK
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: c4975
symbol: iclR
gene_biotype: protein_coding
description:
  Acetate operon repressor; Escherichia coli K-12 ortholog: b4018; Escherichia coli O157:H7 ortholog: z5609.


ensembl_gene_id: c4976
symbol: metH
gene_biotype: protein_coding
description:
  5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: c4978
symbol: c4978
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 145 of 149 are 32.85 pct identical to residues 4 to 137 of 138 from GenPept.129 : >emb|CAC92271.1| (AJ414155) putative membrane protein [Yersinia pestis].


ensembl_gene_id: c4979
symbol: yjbB
gene_biotype: protein_coding
description:
  Hypothetical protein yjbB; Escherichia coli K-12 ortholog: b4020; Escherichia coli O157:H7 ortholog: z5611.


ensembl_gene_id: c4980
symbol: pepE
gene_biotype: protein_coding
description:
  Peptidase E; Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.


ensembl_gene_id: c4981
symbol: c4981
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Escherichia coli K-12 ortholog: b2931; Escherichia coli O157:H7 ortholog: z5613.


ensembl_gene_id: c4982
symbol: c4982
gene_biotype: protein_coding
description:
  PTS system, mannose-specific IID component; EIID-Man; Escherichia coli K-12 ortholog: b1819; Escherichia coli O157:H7 ortholog: z5614.


ensembl_gene_id: c4983
symbol: c4983
gene_biotype: protein_coding
description:
  PTS system, mannose-specific IIC component; EIIC-Man; Escherichia coli K-12 ortholog: b1818; Escherichia coli O157:H7 ortholog: z5615.


ensembl_gene_id: c4986
symbol: c4986
gene_biotype: protein_coding
description:
  D-glucitol-6-phosphate dehydrogenase; Escherichia coli O157:H7 ortholog: z5618; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: c4987
symbol: c4987
gene_biotype: protein_coding
description:
  Putative transcriptional regulator of sorbose uptake and utilization genes; Escherichia coli O157:H7 ortholog: z5619.


ensembl_gene_id: c4988
symbol: yjbC
gene_biotype: protein_coding
description:
  Hypothetical protein yjbC; Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-2604 in 23S ribosomal RNA and from uracil-35 in the anticodon of tRNA(Tyr); Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: c4989
symbol: yjbD
gene_biotype: protein_coding
description:
  Hypothetical protein yjbD; Escherichia coli K-12 ortholog: b4023; Escherichia coli O157:H7 ortholog: z5621.


ensembl_gene_id: c4990
symbol: lysC
gene_biotype: protein_coding
description:
  Lysine-sensitive aspartokinase III; Escherichia coli K-12 ortholog: b4024; Escherichia coli O157:H7 ortholog: z5622; Belongs to the aspartokinase family.


ensembl_gene_id: c4991
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase; Escherichia coli K-12 ortholog: b4025; Escherichia coli O157:H7 ortholog: z5623.


ensembl_gene_id: c4992
symbol: c4992
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 47 of 164 are 51.06 pct identical to residues 17 to 63 of 79 from GenPept.129 : >gb|AAF96960.1| (AE004432) hypothetical protein [Vibrio cholerae].


ensembl_gene_id: c4994
symbol: yjbE
gene_biotype: protein_coding
description:
  Hypothetical protein yjbE precursor; Escherichia coli K-12 ortholog: b4026; Escherichia coli O157:H7 ortholog: z5624.


ensembl_gene_id: c4995
symbol: yjbF
gene_biotype: protein_coding
description:
  Hypothetical lipoprotein yjbF precursor; Escherichia coli K-12 ortholog: b4027; Escherichia coli O157:H7 ortholog: z5625.


ensembl_gene_id: c4996
symbol: yjbG
gene_biotype: protein_coding
description:
  Hypothetical protein yjbG precursor; Escherichia coli K-12 ortholog: b4028; Escherichia coli O157:H7 ortholog: z5626.


ensembl_gene_id: c4997
symbol: yjbH
gene_biotype: protein_coding
description:
  Hypothetical lipoprotein yjbH precursor; Escherichia coli K-12 ortholog: b4029; Escherichia coli O157:H7 ortholog: z5627.


ensembl_gene_id: c5001
symbol: yjbA
gene_biotype: protein_coding
description:
  Hypothetical protein yjbA; Escherichia coli K-12 ortholog: b4030; Escherichia coli O157:H7 ortholog: z5628.


ensembl_gene_id: c5002
symbol: malG
gene_biotype: protein_coding
description:
  Maltose transport system permease protein malG; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: c5003
symbol: malF
gene_biotype: protein_coding
description:
  Maltose transport system permease protein malF; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: c5004
symbol: malE
gene_biotype: protein_coding
description:
  Maltose-binding periplasmic protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: c5005
symbol: malK
gene_biotype: protein_coding
description:
  Maltose/maltodextrin transport ATP-binding protein malK; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.


ensembl_gene_id: c5006
symbol: lamB
gene_biotype: protein_coding
description:
  Maltoporin precursor; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.


ensembl_gene_id: c5007
symbol: malM
gene_biotype: protein_coding
description:
  Maltose operon periplasmic protein precursor; Escherichia coli K-12 ortholog: b4037; Escherichia coli O157:H7 ortholog: z5635.


ensembl_gene_id: c5009
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.


ensembl_gene_id: c5010
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: c5011
symbol: plsB
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate acyltransferase; Escherichia coli K-12 ortholog: b4041; Escherichia coli O157:H7 ortholog: z5640; Belongs to the GPAT/DAPAT family.


ensembl_gene_id: c5013
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: c5014
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: c5015
symbol: dinF
gene_biotype: protein_coding
description:
  DNA-damage-inducible protein F; Escherichia coli K-12 ortholog: b4044; Escherichia coli O157:H7 ortholog: z5643.


ensembl_gene_id: c5016
symbol: yjbJ
gene_biotype: protein_coding
description:
  Protein yjbJ; Escherichia coli K-12 ortholog: b4045; Escherichia coli O157:H7 ortholog: z5644; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: c5017
symbol: yjbK
gene_biotype: protein_coding
description:
  Zinc uptake regulator; Escherichia coli K-12 ortholog: b4046; Escherichia coli O157:H7 ortholog: z5645; Belongs to the Fur family.


ensembl_gene_id: c5018
symbol: yjbN
gene_biotype: protein_coding
description:
  Hypothetical protein yjbN; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: c5019
symbol: yjbO
gene_biotype: protein_coding
description:
  Hypothetical protein yjbO; Escherichia coli K-12 ortholog: b4050; Escherichia coli O157:H7 ortholog: z5648.


ensembl_gene_id: c5020
symbol: qor
gene_biotype: protein_coding
description:
  Quinone oxidoreductase; Escherichia coli K-12 ortholog: b4051; Escherichia coli O157:H7 ortholog: z5649.


ensembl_gene_id: c5021
symbol: c5021
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Residues 70 to 648 of 721 are 36.66 pct identical to residues 6 to 596 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, putative [Thermotoga maritima].


ensembl_gene_id: c5022
symbol: c5022
gene_biotype: protein_coding
description:
  Putative transmembrane transport protein; Residues 18 to 448 of 466 are 40.90 pct identical to residues 24 to 452 of 453 from GenPept.129 : >emb|CAB72806.1| (AL139074) putative transmembrane transport protein [Campylobacter jejuni].


ensembl_gene_id: c5023
symbol: c5023
gene_biotype: protein_coding
description:
  Putative crotonase; Residues 14 to 256 of 259 are 43.20 pct identical to residues 13 to 254 of 256 from GenPept.129 : >gb|AAK65427.1| (AE007264) Putative dehydratase [Sinorhizobium meliloti].


ensembl_gene_id: c5024
symbol: c5024
gene_biotype: protein_coding
description:
  Putative propionate CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.


ensembl_gene_id: c5025
symbol: c5025
gene_biotype: protein_coding
description:
  Putative regulator; Residues 16 to 349 of 353 are 38.46 pct identical to residues 2 to 335 of 347 from GenPept.129 : >emb|CAC47885.1| (AL591793) PUTATIVE TRANSCRIPTION REGULATOR PROTEIN [Sinorhizobium meliloti].


ensembl_gene_id: c5026
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.


ensembl_gene_id: c5028
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase, biosynthetic; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis (By similarity).


ensembl_gene_id: c5029
symbol: c5029
gene_biotype: protein_coding
description:
  Putative transporter; Residues 1 to 181 of 185 are 36.81 pct identical to residues 1 to 182 of 191 from GenPept.129 : >gb|AAG05346.1|AE004622_8 (AE004622) probable transporter [Pseudomonas aeruginosa].


ensembl_gene_id: c5030
symbol: c5030
gene_biotype: protein_coding
description:
  NadR homolog; Residues 15 to 342 of 342 are 32.32 pct identical to residues 4 to 317 of 323 from GenPept.129 : >emb|CAB07007.1| (Z92669) nadR [Mycobacterium tuberculosis H37Rv].


ensembl_gene_id: c5031
symbol: tyrB
gene_biotype: protein_coding
description:
  Aromatic-amino-acid aminotransferase; Escherichia coli K-12 ortholog: b4054; Escherichia coli O157:H7 ortholog: z5652.


ensembl_gene_id: c5032
symbol: c5032
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase E1 component; Escherichia coli K-12 ortholog: b0726; Escherichia coli O157:H7 ortholog: z0880.


ensembl_gene_id: c5034
symbol: c5034
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; Escherichia coli K-12 ortholog: b0727; Escherichia coli O157:H7 ortholog: z0881.


ensembl_gene_id: c5035
symbol: c5035
gene_biotype: protein_coding
description:
  Putative 2-oxoglutarate dehydrogenase; Residues 1 to 468 of 472 are 49.04 pct identical to residues 1 to 470 of 474 from SwissProt.40 : >sp|P52992|DLDH_ALCEU DIHYDROLIPOAMIDE DEHYDROGENASE (E3 COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX).


ensembl_gene_id: c5038
symbol: c5038
gene_biotype: protein_coding
description:
  Putative membrane-bound protein; Residues 10 to 499 of 501 are 60.28 pct identical to residues 20 to 511 of 513 from SwissProt.40 : >sp|Q07252|MEMP_ALCEU MEMBRANE PROTEIN.


ensembl_gene_id: c5039
symbol: c5039
gene_biotype: protein_coding
description:
  Putative lactate dehydrogenase; Residues 15 to 344 of 369 are 44.87 pct identical to residues 1 to 332 of 349 from SwissProt.40 : >sp|Q07251|LDH_ALCEU L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family.


ensembl_gene_id: c5040
symbol: c5040
gene_biotype: protein_coding
description:
  Putative c4-dicarboxylate transport transcriptional Regulatory protein; Residues 10 to 441 of 452 are 51.61 pct identical to residues 7 to 439 of 448 from SwissProt.40 : >sp|P10046|DCTD_RHILE C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD.


ensembl_gene_id: c5041
symbol: c5041
gene_biotype: protein_coding
description:
  Putative transport sensor protein; Residues 20 to 591 of 606 are 31.81 pct identical to residues 28 to 612 of 633 from GenPept.129 : >gb|AAG04725.1|AE004563_2 (AE004563) probable two-component sensor [Pseudomonas aeruginosa].


ensembl_gene_id: c5045
symbol: aphA
gene_biotype: protein_coding
description:
  Class B acid phosphatase precursor; Escherichia coli K-12 ortholog: b4055; Escherichia coli O157:H7 ortholog: z5654; Belongs to the class B bacterial acid phosphatase family.


ensembl_gene_id: c5046
symbol: yjbQ
gene_biotype: protein_coding
description:
  Hypothetical protein yjbQ; Escherichia coli K-12 ortholog: b4056; Escherichia coli O157:H7 ortholog: z5655.


ensembl_gene_id: c5048
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: c5049
symbol: ssb
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: c5050
symbol: yjcB
gene_biotype: protein_coding
description:
  Hypothetical protein yjcB; Escherichia coli K-12 ortholog: b4060; Escherichia coli O157:H7 ortholog: z5659.


ensembl_gene_id: c5052
symbol: yjcC
gene_biotype: protein_coding
description:
  Hypothetical protein yjcC; Escherichia coli K-12 ortholog: b4061; Escherichia coli O157:H7 ortholog: z5660.


ensembl_gene_id: c5053
symbol: soxS
gene_biotype: protein_coding
description:
  Regulatory protein soxS; Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and the nfo promoters (By similarity).


ensembl_gene_id: c5054
symbol: soxR
gene_biotype: protein_coding
description:
  Redox-sensitive transcriptional activator soxR; Escherichia coli K-12 ortholog: b4063; Escherichia coli O157:H7 ortholog: z5662.


ensembl_gene_id: c5056
symbol: c5056
gene_biotype: protein_coding
description:
  Hypothetical protein yjcD; Escherichia coli K-12 ortholog: b4064; Escherichia coli O157:H7 ortholog: z5663.


ensembl_gene_id: c5057
symbol: c5057
gene_biotype: protein_coding
description:
  Putative Na(+)/H(+) exchanger yjcE; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: c5058
symbol: c5058
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Residues 1 to 291 of 294 are 89.04 pct identical to residues 1 to 292 of 295 from GenPept.129 : >emb|CAD09254.1| (AL627282) lysR family regulatory protein [Salmonella enterica subsp. enterica serovar Typhi]; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: c5060
symbol: c5060
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 133 of 134 are 84.96 pct identical to residues 3 to 135 of 136 from GenPept.129 : >gb|AAL23095.1| (AE008900) putative inner membrane protein [Salmonella typhimurium LT2].


ensembl_gene_id: c5061
symbol: c5061
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 229 of 229 are 89.95 pct identical to residues 1 to 229 of 229 from GenPept.129 : >gb|AAL23096.1| (AE008900) putative inner membrane protein [Salmonella typhimurium LT2].


ensembl_gene_id: c5062
symbol: yjcG
gene_biotype: protein_coding
description:
  Putative symporter yjcG; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: c5063
symbol: yjcH
gene_biotype: protein_coding
description:
  Hypothetical protein yjcH; Escherichia coli K-12 ortholog: b4068; Escherichia coli O157:H7 ortholog: z5667.


ensembl_gene_id: c5064
symbol: acs
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.


ensembl_gene_id: c5066
symbol: nrfA
gene_biotype: protein_coding
description:
  Cytochrome c552 precursor; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.


ensembl_gene_id: c5070
symbol: nrfE
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein nrfE; Escherichia coli K-12 ortholog: b4074; Escherichia coli O157:H7 ortholog: z5673.


ensembl_gene_id: c5071
symbol: nrfF
gene_biotype: protein_coding
description:
  Formate-dependent nitrite reductase complex nrfF subunit precursor; Possible subunit of a heme lyase.


ensembl_gene_id: c5072
symbol: nrfG
gene_biotype: protein_coding
description:
  Formate-dependent nitrite reductase complex nrfG subunit; Escherichia coli K-12 ortholog: b4076; Escherichia coli O157:H7 ortholog: z5675.


ensembl_gene_id: c5074
symbol: gltP
gene_biotype: protein_coding
description:
  Proton glutamate symport protein; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.


ensembl_gene_id: c5076
symbol: yjcO
gene_biotype: protein_coding
description:
  Hypothetical protein yjcO precursor; Escherichia coli K-12 ortholog: b4078; Escherichia coli O157:H7 ortholog: z5677.


ensembl_gene_id: c5077
symbol: yddO
gene_biotype: protein_coding
description:
  Hypothetical ABC transporter ATP-binding protein yddO; Escherichia coli K-12 ortholog: b1483; Escherichia coli O157:H7 ortholog: z2227.


ensembl_gene_id: c5078
symbol: c5078
gene_biotype: protein_coding
description:
  Putative oligopeptide ABC transporter; Residues 21 to 287 of 298 are 62.98 pct identical to residues 1 to 281 of 292 from GenPept.129 : >emb|CAC92681.1| (AJ414157) putative ABC transporter transporter, ATP-binding protein [Yersinia pestis].


ensembl_gene_id: c5079
symbol: yddQ
gene_biotype: protein_coding
description:
  Hypothetical ABC transporter permease protein yddQ; Escherichia coli K-12 ortholog: b1485; Escherichia coli O157:H7 ortholog: z2225.


ensembl_gene_id: c5080
symbol: yddR
gene_biotype: protein_coding
description:
  Hypothetical ABC transporter permease protein yddR; Escherichia coli K-12 ortholog: b1486; Escherichia coli O157:H7 ortholog: z2224.


ensembl_gene_id: c5081
symbol: c5081
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 9 to 506 of 522 are 28.96 pct identical to residues 14 to 499 of 516 from MG1655 : b1487.


ensembl_gene_id: c5085
symbol: yjcP
gene_biotype: protein_coding
description:
  Hypothetical outer-membrane lipoprotein yjcP precursor; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.


ensembl_gene_id: c5086
symbol: yjcQ
gene_biotype: protein_coding
description:
  Hypothetical transporter yjcQ; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.


ensembl_gene_id: c5087
symbol: yjcR
gene_biotype: protein_coding
description:
  Hypothetical protein yjcR; Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.


ensembl_gene_id: c5088
symbol: ytcA
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 17 to 107 of 107 are 95.60 pct identical to residues 1 to 91 of 91 from GenPept.129 : >dbj|BAB38488.1| (AP002568) hypothetical protein [Escherichia coli O157:H7].


ensembl_gene_id: c5089
symbol: yjcS
gene_biotype: protein_coding
description:
  Hypothetical protein yjcS; Escherichia coli K-12 ortholog: b4083; Escherichia coli O157:H7 ortholog: z5683.


ensembl_gene_id: c5092
symbol: yjcV
gene_biotype: protein_coding
description:
  D-allose transport system permease protein alsC; Escherichia coli K-12 ortholog: b4086; Escherichia coli O157:H7 ortholog: z5251; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: c5093
symbol: yjcW
gene_biotype: protein_coding
description:
  D-allose transport ATP-binding protein alsA; Escherichia coli K-12 ortholog: b4087; Escherichia coli O157:H7 ortholog: z3404.


ensembl_gene_id: c5095
symbol: rpiR
gene_biotype: protein_coding
description:
  Protein rpiR; Regulatory protein involved in rpiB gene repression. Also involved in als operon repression (By similarity).


ensembl_gene_id: c5102
symbol: phnL
gene_biotype: protein_coding
description:
  Phosphonates transport ATP-binding protein phnL; Escherichia coli K-12 ortholog: b4096; Escherichia coli O157:H7 ortholog: z5699.


ensembl_gene_id: c5103
symbol: phnK
gene_biotype: protein_coding
description:
  Phosphonates transport ATP-binding protein phnK; Escherichia coli K-12 ortholog: b4097; Escherichia coli O157:H7 ortholog: z5700.


ensembl_gene_id: c5104
symbol: phnJ
gene_biotype: protein_coding
description:
  PhnJ protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.


ensembl_gene_id: c5108
symbol: phnF
gene_biotype: protein_coding
description:
  Probable transcriptional regulator phnF; Escherichia coli K-12 ortholog: b4102; Escherichia coli O157:H7 ortholog: z5705.


ensembl_gene_id: c5110
symbol: phnD
gene_biotype: protein_coding
description:
  Phosphonates-binding periplasmic protein precursor; Escherichia coli K-12 ortholog: b4105; Escherichia coli O157:H7 ortholog: z5707.


ensembl_gene_id: c5111
symbol: phnC
gene_biotype: protein_coding
description:
  Phosphonates transport ATP-binding protein phnC; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: c5113
symbol: phnA
gene_biotype: protein_coding
description:
  PhnA protein; Escherichia coli K-12 ortholog: b4108; Escherichia coli O157:H7 ortholog: z5710; Belongs to the YjdM family.


ensembl_gene_id: c5114
symbol: yjdA
gene_biotype: protein_coding
description:
  Hypothetical protein yjdA; Escherichia coli K-12 ortholog: b4109; Escherichia coli O157:H7 ortholog: z5711.


ensembl_gene_id: c5115
symbol: yjcZ
gene_biotype: protein_coding
description:
  Hypothetical protein yjcZ; Escherichia coli K-12 ortholog: b4110; Escherichia coli O157:H7 ortholog: z5712.


ensembl_gene_id: c5116
symbol: proP
gene_biotype: protein_coding
description:
  Proline/betaine transporter; Proline porter II; Escherichia coli K-12 ortholog: b4111; Escherichia coli O157:H7 ortholog: z5713.


ensembl_gene_id: c5117
symbol: basS
gene_biotype: protein_coding
description:
  Sensor protein basS/pmrB; Escherichia coli K-12 ortholog: b4112; Escherichia coli O157:H7 ortholog: z5714.


ensembl_gene_id: c5118
symbol: basR
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein basR/pmrA; Escherichia coli K-12 ortholog: b4113; Escherichia coli O157:H7 ortholog: z5715.


ensembl_gene_id: c5119
symbol: yjdB
gene_biotype: protein_coding
description:
  Hypothetical protein yjdB; Escherichia coli K-12 ortholog: b4114; Escherichia coli O157:H7 ortholog: z5716.


ensembl_gene_id: c5120
symbol: yjdE
gene_biotype: protein_coding
description:
  Hypothetical transport protein yjdE; Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach. Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons (By similarity); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.


ensembl_gene_id: c5121
symbol: adiY
gene_biotype: protein_coding
description:
  Putative Regulatory protein adiY; Escherichia coli K-12 ortholog: b4116; Escherichia coli O157:H7 ortholog: z5718.


ensembl_gene_id: c5122
symbol: adiA
gene_biotype: protein_coding
description:
  Biodegradative arginine decarboxylase; Escherichia coli K-12 ortholog: b4117; Escherichia coli O157:H7 ortholog: z5719.


ensembl_gene_id: c5123
symbol: melR
gene_biotype: protein_coding
description:
  Melibiose operon Regulatory protein; Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site (By similarity).


ensembl_gene_id: c5124
symbol: melA
gene_biotype: protein_coding
description:
  Alpha-galactosidase; Escherichia coli K-12 ortholog: b4119; Escherichia coli O157:H7 ortholog: z5721.


ensembl_gene_id: c5127
symbol: fumB
gene_biotype: protein_coding
description:
  Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: c5128
symbol: dcuB
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter dcuB; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: c5130
symbol: yjdG
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein dcuR; Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4- dicarboxylate transporter dctA (By similarity).


ensembl_gene_id: c5131
symbol: yjdH
gene_biotype: protein_coding
description:
  Sensor protein dcuS; Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; dcuC; sdhCDAB; etc.). Weakly regulates the aerobic C4- dicarboxylate transporter dctA. Activates DcuR by phosphorylation (By similarity).


ensembl_gene_id: c5133
symbol: yjdI
gene_biotype: protein_coding
description:
  Hypothetical protein yjdI; Escherichia coli K-12 ortholog: b4126; Escherichia coli O157:H7 ortholog: z5728.


ensembl_gene_id: c5134
symbol: yjdJ
gene_biotype: protein_coding
description:
  Hypothetical protein yjdJ; Escherichia coli K-12 ortholog: b4127; Escherichia coli O157:H7 ortholog: z5729.


ensembl_gene_id: c5136
symbol: ghoT
gene_biotype: protein_coding
description:
  Hypothetical protein ydcX; Toxic component of a type V toxin-antitoxin (TA) system. Causes membrane damage when induced by MqsR, slowing cell growth and leading to the formation of dormant persister cells; involved with GhoS, its antitoxin, in reducing cell growth during antibacterial stress. Its toxic effects are neutralized by GhoS, which digests ghoT transcripts in a sequence-specific manner.


ensembl_gene_id: c5138
symbol: lysU
gene_biotype: protein_coding
description:
  Lysyl-tRNA synthetase, heat inducible; Escherichia coli K-12 ortholog: b4129; Escherichia coli O157:H7 ortholog: z5732; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: c5139
symbol: yjdL
gene_biotype: protein_coding
description:
  Hypothetical transporter yjdL; Escherichia coli K-12 ortholog: b4130; Escherichia coli O157:H7 ortholog: z5733.


ensembl_gene_id: c5140
symbol: cadA
gene_biotype: protein_coding
description:
  Lysine decarboxylase, inducible; Escherichia coli K-12 ortholog: b4131; Escherichia coli O157:H7 ortholog: z5734.


ensembl_gene_id: c5142
symbol: cadC
gene_biotype: protein_coding
description:
  Transcriptional activator cadC; Escherichia coli K-12 ortholog: b4133; Escherichia coli O157:H7 ortholog: z5736.


ensembl_gene_id: c5143
symbol: c5143
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 80 of 80 are 100.00 pct identical to residues 1 to 80 of 80 from GenPept.129 : >gb|AAL67384.1|AF447814_52 (AF447814) L0012-like protein [Escherichia coli].


ensembl_gene_id: c5153
symbol: c5153
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 156 of 176 are 91.02 pct identical to residues 1 to 156 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c5154
symbol: c5154
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 143 of 148 are 86.95 pct identical to residues 161 to 298 of 319 from GenPept.129 : >gb|AAL67347.1|AF447814_15 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c5158
symbol: c5158
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 161 of 260 are 100.00 pct identical to residues 1 to 161 of 260 from GenPept.129 : >gb|AAL67392.1|AF447814_60 (AF447814) putative intergenic-region protein [Escherichia coli].


ensembl_gene_id: c5162
symbol: c5162
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 12 to 294 of 294 are 35.33 pct identical to residues 12 to 289 of 289 from MG1655 : b2632.


ensembl_gene_id: c5163
symbol: c5163
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 2 to 317 of 317 are 100.00 pct identical to residues 1 to 316 of 316 from GenPept.129 : >gb|AAL67396.1|AF447814_64 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c5164
symbol: c5164
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 30 to 274 of 291 are 100.00 pct identical to residues 1 to 245 of 254 from GenPept.129 : >gb|AAL67397.1|AF447814_65 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c5169
symbol: c5169
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 78 of 78 are 100.00 pct identical to residues 1 to 78 of 78 from GenPept.129 : >gb|AAL67400.1|AF447814_68 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c5172
symbol: c5172
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 246 of 246 are 100.00 pct identical to residues 1 to 246 of 246 from GenPept.129 : >gb|AAL67401.1|AF447814_69 (AF447814) intergenic-region protein [Escherichia coli].


ensembl_gene_id: c5174
symbol: c5174
gene_biotype: protein_coding
description:
  Putative iron-regulated outer membrane virulence protein; Residues 1 to 682 of 682 are 100.00 pct identical to residues 1 to 682 of 682 from GenPept.129 : >gb|AAL67402.1|AF447814_70 (AF447814) IrgA-like protein [Escherichia coli].


ensembl_gene_id: c5175
symbol: c5175
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 43 of 43 are 88.37 pct identical to residues 358 to 400 of 400 from GenPept.129 : >gb|AAK69271.1|AF336309_66 (AF336309) unknown [Yersinia enterocolitica].


ensembl_gene_id: c5179
symbol: papG_2
gene_biotype: protein_coding
description:
  PapG protein; Residues 1 to 336 of 336 are 56.72 pct identical to residues 1 to 335 of 335 from SwissProt.40 : >sp|P42188|PRSG_ECOLI FIMBRIAL PROTEIN PRSG PRECURSOR (ADHESIN).


ensembl_gene_id: c5182
symbol: papK_2
gene_biotype: protein_coding
description:
  PapK protein; Residues 2 to 179 of 179 are 100.00 pct identical to residues 1 to 178 of 178 from SwissProt.40 : >sp|P42190|PAPK_ECOLI PROTEIN PAPK PRECURSOR.


ensembl_gene_id: c5185
symbol: papD_2
gene_biotype: protein_coding
description:
  PapD protein; Residues 3 to 244 of 244 are 40.74 pct identical to residues 9 to 246 of 250 from MG1655 : b2336.


ensembl_gene_id: c5186
symbol: papC_2
gene_biotype: protein_coding
description:
  PapC protein; Residues 8 to 839 of 843 are 43.20 pct identical to residues 1 to 842 of 879 from EDL933 : z3600.


ensembl_gene_id: c5188
symbol: papA_2
gene_biotype: protein_coding
description:
  PapA protein; Residues 12 to 198 of 198 are 99.46 pct identical to residues 1 to 187 of 187 from SwissProt.40 : >sp|P04740|FMK1_ECOLI KS71A FIMBRILLIN PRECURSOR (P-FIMBRIAL ANTIGEN).


ensembl_gene_id: c5189
symbol: papI_2
gene_biotype: protein_coding
description:
  PapI protein; Residues 1 to 73 of 73 are 100.00 pct identical to residues 5 to 77 of 77 from SwissProt.40 : >sp|P25395|KS7A_ECOLI P FIMBRIAL REGULATORY PROTEIN KS71A.


ensembl_gene_id: c5191
symbol: c5191
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 148 of 148 are 100.00 pct identical to residues 1 to 148 of 148 from GenPept.129 : >gb|AAL67420.1|AF447814_88 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c5193
symbol: c5193
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 89 to 238 of 238 are 100.00 pct identical to residues 30 to 179 of 179 from GenPept.129 : >gb|AAL67421.1|AF447814_89 (AF447814) unknown [Escherichia coli].


ensembl_gene_id: c5195
symbol: c5195
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 4 to 102 of 108 are 32.32 pct identical to residues 7 to 103 of 197 from GenPept.129 : >gb|AAL08430.1|AF326777_5 (AF326777) unknown [Shigella flexneri 2a].


ensembl_gene_id: c5198
symbol: c5198
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 56 of 56 are 96.42 pct identical to residues 66 to 121 of 121 from GenPept.129 : >gb|AAG54583.1|AE005203_12 (AE005203) unknown protein encoded by IS2 [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c5201
symbol: pgtP
gene_biotype: protein_coding
description:
  Transporter protein; Residues 1 to 406 of 454 are 89.16 pct identical to residues 1 to 405 of 406 from SwissProt.40 : >sp|P12681|PGTP_SALTY Phosphoglycerate transporter protein.


ensembl_gene_id: c5202
symbol: pgtC
gene_biotype: protein_coding
description:
  Regulatory protein; Residues 41 to 435 of 435 are 78.48 pct identical to residues 3 to 397 of 397 from SwissProt.40 : >sp|P37591|PGTC_SALTY PHOSPHOGLYCERATE TRANSPORT REGULATORY PROTEIN PGTC PRECURSOR.


ensembl_gene_id: c5203
symbol: pgtB
gene_biotype: protein_coding
description:
  Regulatory protein; Residues 139 to 669 of 669 are 79.28 pct identical to residues 63 to 593 of 593 from SwissProt.40 : >sp|P37433|PGTB_SALTY PHOSPHOGLYCERATE TRANSPORT SYSTEM SENSOR PROTEIN PGTB.


ensembl_gene_id: c5204
symbol: pgtA
gene_biotype: protein_coding
description:
  Transport activator; Residues 4 to 417 of 418 are 79.95 pct identical to residues 1 to 414 of 415 from SwissProt.40 : >sp|P06184|PGTA_SALTY PHOSPHOGLYCERATE TRANSPORT SYSTEM TRANSCRIPTIONAL REGULATORY PROTEIN PGTA.


ensembl_gene_id: c5206
symbol: c5206
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 14 to 102 of 102 are 95.50 pct identical to residues 1 to 89 of 89 from GenPept.129 : >dbj|BAB34811.1| (AP002554) putative transcriptional regulator [Escherichia coli O157:H7].


ensembl_gene_id: c5207
symbol: c5207
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 19 to 51 of 51 are 100.00 pct identical to residues 180 to 212 of 212 from GenPept.129 : >gb|AAG55759.1|AE005312_5 (AE005312) unknown [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c5215
symbol: c5215
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Residues 5 to 587 of 587 are 96.39 pct identical to residues 1 to 583 of 774 from GenPept.129 : >gb|AAK00457.1| (AF200692) unknown [Shigella flexneri 2a].


ensembl_gene_id: c5218
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein dsbD precursor; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: c5219
symbol: cutA
gene_biotype: protein_coding
description:
  Periplasmic divalent cation tolerance protein cutA; Involved in resistance toward heavy metals. Belongs to the CutA family.


ensembl_gene_id: c5220
symbol: dcuA
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter dcuA; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: c5221
symbol: c5221
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 349 to 483 of 483 are 100.00 pct identical to residues 1 to 135 of 135 from GenPept.129 : >emb|CAA26174.1| (X02307) URF 4 [Escherichia coli].


ensembl_gene_id: c5222
symbol: aspA
gene_biotype: protein_coding
description:
  Aspartate ammonia-lyase; Escherichia coli K-12 ortholog: b4139; Escherichia coli O157:H7 ortholog: z5744; Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.


ensembl_gene_id: c5223
symbol: c5223
gene_biotype: protein_coding
description:
  FxsA protein; Suppressor of F exclusion of phage T7; Escherichia coli K-12 ortholog: b4140; Escherichia coli O157:H7 ortholog: z5745.


ensembl_gene_id: c5224
symbol: yjeH
gene_biotype: protein_coding
description:
  Hypothetical protein yjeH; Escherichia coli K-12 ortholog: b4141; Escherichia coli O157:H7 ortholog: z5746.


ensembl_gene_id: c5226
symbol: mopB
gene_biotype: protein_coding
description:
  10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: c5227
symbol: mopA
gene_biotype: protein_coding
description:
  60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: c5228
symbol: yjeI
gene_biotype: protein_coding
description:
  Hypothetical protein yjeI precursor; Escherichia coli K-12 ortholog: b4144; Escherichia coli O157:H7 ortholog: z5749.


ensembl_gene_id: c5230
symbol: yjeJ
gene_biotype: protein_coding
description:
  Hypothetical protein yjeJ; Escherichia coli K-12 ortholog: b4145; Escherichia coli O157:H7 ortholog: z5750.


ensembl_gene_id: c5231
symbol: yjeK
gene_biotype: protein_coding
description:
  Hypothetical protein yjeK; Escherichia coli K-12 ortholog: b4146; Escherichia coli O157:H7 ortholog: z5751.


ensembl_gene_id: c5232
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: c5234
symbol: ecnA
gene_biotype: protein_coding
description:
  Entericidin A; Acts as antidote to the effect of entericidin B. Belongs to the EcnA/EcnB lipoprotein family.


ensembl_gene_id: c5235
symbol: ecnB
gene_biotype: protein_coding
description:
  Entericidin B; Plays a role in the bacteriolysis. Is activated under conditions of high osmolarity by the factor sigma S. Entericidin A functions as an antidote (By similarity); Belongs to the EcnA/EcnB lipoprotein family.


ensembl_gene_id: c5236
symbol: sugE
gene_biotype: protein_coding
description:
  SugE protein; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons. Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.


ensembl_gene_id: c5237
symbol: blc
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein blc precursor; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: c5238
symbol: ampC
gene_biotype: protein_coding
description:
  Beta-lactamase precursor; Escherichia coli K-12 ortholog: b4150; Escherichia coli O157:H7 ortholog: z5757.


ensembl_gene_id: c5239
symbol: frdD
gene_biotype: protein_coding
description:
  Fumarate reductase 13 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: c5240
symbol: frdC
gene_biotype: protein_coding
description:
  Fumarate reductase 15 kDa hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: c5241
symbol: frdB
gene_biotype: protein_coding
description:
  Fumarate reductase iron-sulfur protein; Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth. Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: c5242
symbol: frdA
gene_biotype: protein_coding
description:
  Fumarate reductase flavoprotein subunit; Escherichia coli K-12 ortholog: b4154; Escherichia coli O157:H7 ortholog: z5762.


ensembl_gene_id: c5243
symbol: yjeA
gene_biotype: protein_coding
description:
  Putative lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta- lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF- P 'Lys-34'; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.


ensembl_gene_id: c5244
symbol: yjeM
gene_biotype: protein_coding
description:
  Hypothetical transporter yjeM; Escherichia coli K-12 ortholog: b4156; Escherichia coli O157:H7 ortholog: z5764.


ensembl_gene_id: c5245
symbol: yjeP
gene_biotype: protein_coding
description:
  Hypothetical protein yjeP precursor; Escherichia coli K-12 ortholog: b4159; Escherichia coli O157:H7 ortholog: z5765.


ensembl_gene_id: c5247
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: c5248
symbol: yjeQ
gene_biotype: protein_coding
description:
  Hypothetical protein yjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: c5250
symbol: yjeS
gene_biotype: protein_coding
description:
  Putative electron transport protein yjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: c5251
symbol: yjeF
gene_biotype: protein_coding
description:
  Hypothetical protein yjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of bot [...]


ensembl_gene_id: c5252
symbol: yjeE
gene_biotype: protein_coding
description:
  Hypothetical protein yjeE; Escherichia coli K-12 ortholog: b4168; Escherichia coli O157:H7 ortholog: z5775.


ensembl_gene_id: c5253
symbol: amiB
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase amiB precursor; Escherichia coli K-12 ortholog: b4169; Escherichia coli O157:H7 ortholog: z5776.


ensembl_gene_id: c5254
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: c5255
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: c5256
symbol: hfq
gene_biotype: protein_coding
description:
  Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: c5257
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein hflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: c5259
symbol: hflC
gene_biotype: protein_coding
description:
  HflC protein; HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda. HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins (By similarity).


ensembl_gene_id: c5260
symbol: yjeT
gene_biotype: protein_coding
description:
  Hypothetical protein yjeT; Escherichia coli K-12 ortholog: b4176; Escherichia coli O157:H7 ortholog: z5783.


ensembl_gene_id: c5261
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: c5262
symbol: yjeB
gene_biotype: protein_coding
description:
  Hypothetical protein yjeB; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.


ensembl_gene_id: c5263
symbol: vacB
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.


ensembl_gene_id: c5264
symbol: yjfH
gene_biotype: protein_coding
description:
  Hypothetical tRNA/rRNA methyltransferase yjfH; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.


ensembl_gene_id: c5265
symbol: yjfI
gene_biotype: protein_coding
description:
  Hypothetical protein yjfI; Escherichia coli K-12 ortholog: b4181; Escherichia coli O157:H7 ortholog: z5788.


ensembl_gene_id: c5266
symbol: yjfJ
gene_biotype: protein_coding
description:
  Hypothetical protein yjfJ precursor; Escherichia coli K-12 ortholog: b4182; Escherichia coli O157:H7 ortholog: z5789; Belongs to the PspA/IM30 family.


ensembl_gene_id: c5267
symbol: yjfK
gene_biotype: protein_coding
description:
  Hypothetical protein yjfK; Escherichia coli K-12 ortholog: b4183; Escherichia coli O157:H7 ortholog: z5790.


ensembl_gene_id: c5268
symbol: yjfL
gene_biotype: protein_coding
description:
  Hypothetical protein yjfL; Escherichia coli K-12 ortholog: b4184; Escherichia coli O157:H7 ortholog: z5791.


ensembl_gene_id: c5269
symbol: c5269
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 23 to 55 of 55 are 90.90 pct identical to residues 100 to 132 of 132 from GenPept.129 : >gb|AAG59380.1|AE005651_9 (AE005651) yjfL gene product [Escherichia coli O157:H7 EDL933].


ensembl_gene_id: c5272
symbol: yjfM
gene_biotype: protein_coding
description:
  Hypothetical protein yjfM; Escherichia coli K-12 ortholog: b4185; Escherichia coli O157:H7 ortholog: z5792.


ensembl_gene_id: c5274
symbol: yjfC
gene_biotype: protein_coding
description:
  Hypothetical protein yjfC; Escherichia coli K-12 ortholog: b4186; Escherichia coli O157:H7 ortholog: z5793.


ensembl_gene_id: c5276
symbol: yjfN
gene_biotype: protein_coding
description:
  Hypothetical protein yjfN; Escherichia coli K-12 ortholog: b4188; Escherichia coli O157:H7 ortholog: z5795.


ensembl_gene_id: c5277
symbol: yjfO
gene_biotype: protein_coding
description:
  Hypothetical lipoprotein yjfO precursor; Escherichia coli K-12 ortholog: b4189; Escherichia coli O157:H7 ortholog: z5796.


ensembl_gene_id: c5278
symbol: yjfP
gene_biotype: protein_coding
description:
  Hypothetical protein yjfP; Escherichia coli K-12 ortholog: b4190; Escherichia coli O157:H7 ortholog: z5799.


ensembl_gene_id: c5280
symbol: yjfR
gene_biotype: protein_coding
description:
  Hypothetical protein yjfR; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family.


ensembl_gene_id: c5281
symbol: sgaT
gene_biotype: protein_coding
description:
  Putative transport protein sgaT; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.


ensembl_gene_id: c5283
symbol: sgaB
gene_biotype: protein_coding
description:
  Unknown pentitol phosphotransferase enzyme II, B component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.


ensembl_gene_id: c5284
symbol: ptxA
gene_biotype: protein_coding
description:
  Unknown pentitol phosphotransferase enzyme II, A component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.


ensembl_gene_id: c5285
symbol: sgaH
gene_biotype: protein_coding
description:
  Probable hexulose-6-phosphate synthase; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization. Belongs to the HPS/KGPDC family. KGPDC subfamily.


ensembl_gene_id: c5287
symbol: sgaU
gene_biotype: protein_coding
description:
  Putative hexulose-6-phosphate isomerase; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the L-ribulose-5-phosphate 3-epimerase family.


ensembl_gene_id: c5288
symbol: sgaE
gene_biotype: protein_coding
description:
  Probable sugar isomerase sgaE; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization.


ensembl_gene_id: c5289
symbol: yjfY
gene_biotype: protein_coding
description:
  Hypothetical protein yjfY precursor; Escherichia coli K-12 ortholog: b4199; Escherichia coli O157:H7 ortholog: z5808.


ensembl_gene_id: c5292
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: c5297
symbol: c5297
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 200 of 203 are 26.49 pct identical to residues 235 to 430 of 435 from GenPept.129 : >gb|AAK24734.1| (AE005942) hypothetical protein [Caulobacter crescentus CB15].


ensembl_gene_id: c5299
symbol: c5299
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Residues 29 to 688 of 690 are 35.69 pct identical to residues 5 to 663 of 664 from GenPept.129 : >gb|AAD35512.1|AE001721_11 (AE001721) oxidoreductase, putative [Thermotoga maritima].


ensembl_gene_id: c5300
symbol: c5300
gene_biotype: protein_coding
description:
  Putative acetyl-CoA:acetoacetyl-CoA transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.


ensembl_gene_id: c5301
symbol: c5301
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 4 to 255 of 258 are 36.75 pct identical to residues 3 to 254 of 256 from GenPept.129 : >gb|AAK65427.1| (AE007264) Putative dehydratase [Sinorhizobium meliloti]; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: c5302
symbol: c5302
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 268 of 280 are 97.76 pct identical to residues 1 to 268 of 294 from GenPept.129 : >gb|AAL50626.1|AF417476_3 (AF417476) unknown [Shigella flexneri].


ensembl_gene_id: c5303
symbol: c5303
gene_biotype: protein_coding
description:
  Putative oxoacyl reductase; Residues 85 to 201 of 263 are 99.14 pct identical to residues 20 to 136 of 137 from GenPept.129 : >gb|AAL50625.1|AF417476_2 (AF417476) unknown [Shigella flexneri].


ensembl_gene_id: c5304
symbol: c5304
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 132 to 239 of 239 are 97.22 pct identical to residues 1 to 108 of 108 from MG1655 : b4205.


ensembl_gene_id: c5305
symbol: ytfB
gene_biotype: protein_coding
description:
  Hypothetical protein ytfB; Escherichia coli K-12 ortholog: b4206; Escherichia coli O157:H7 ortholog: z5817.


ensembl_gene_id: c5306
symbol: fklB
gene_biotype: protein_coding
description:
  FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase; Escherichia coli K-12 ortholog: b4207; Escherichia coli O157:H7 ortholog: z5818.


ensembl_gene_id: c5307
symbol: cycA
gene_biotype: protein_coding
description:
  D-serine/D-alanine/glycine transporter; Permease that is involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; is the only transporter of D-alanine. Transports D-serine less efficiently than CycA; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.


ensembl_gene_id: c5308
symbol: ytfE
gene_biotype: protein_coding
description:
  Hypothetical protein ytfE; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.


ensembl_gene_id: c5309
symbol: ytfF
gene_biotype: protein_coding
description:
  Hypothetical protein ytfF; Escherichia coli K-12 ortholog: b4210; Escherichia coli O157:H7 ortholog: z5821.


ensembl_gene_id: c5310
symbol: ytfG
gene_biotype: protein_coding
description:
  Hypothetical protein ytfG; Escherichia coli K-12 ortholog: b4211; Escherichia coli O157:H7 ortholog: z5822.


ensembl_gene_id: c5311
symbol: ytfH
gene_biotype: protein_coding
description:
  Hypothetical protein ytfH; Escherichia coli K-12 ortholog: b4212; Escherichia coli O157:H7 ortholog: z5823.


ensembl_gene_id: c5312
symbol: c5312
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 1 to 78 of 78 are 97.43 pct identical to residues 570 to 647 of 647 from MG1655 : b4213.


ensembl_gene_id: c5313
symbol: cysQ
gene_biotype: protein_coding
description:
  CysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: c5315
symbol: ytfK
gene_biotype: protein_coding
description:
  Hypothetical protein ytfK; Escherichia coli K-12 ortholog: b4217; Escherichia coli O157:H7 ortholog: z5828.


ensembl_gene_id: c5316
symbol: ytfL
gene_biotype: protein_coding
description:
  Hypothetical protein ytfL; Escherichia coli K-12 ortholog: b4218; Escherichia coli O157:H7 ortholog: z5829.


ensembl_gene_id: c5317
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase msrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).


ensembl_gene_id: c5318
symbol: ytfM
gene_biotype: protein_coding
description:
  Hypothetical protein ytfM precursor; Escherichia coli K-12 ortholog: b4220; Escherichia coli O157:H7 ortholog: z5831.


ensembl_gene_id: c5319
symbol: ytfN
gene_biotype: protein_coding
description:
  Hypothetical protein ytfN; Escherichia coli K-12 ortholog: b4221; Escherichia coli O157:H7 ortholog: z5832.


ensembl_gene_id: c5320
symbol: ytfP
gene_biotype: protein_coding
description:
  Hypothetical protein ytfP; Escherichia coli K-12 ortholog: b4222; Escherichia coli O157:H7 ortholog: z5833; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: c5321
symbol: esiB
gene_biotype: protein_coding
description:
  Putative conserved protein; Upon host (human neutrophil) infection interferes with productive FCAR signaling, inhibiting secreted IgA (SIgA) effector functions and probably avoiding neutrophil activation. Inhibits the SIgA-mediated oxidative burst by neutrophils, decreases generation of ROS (reactive oxygen species) by neutrophils and reduces chemotaxis by neutrophils, all of which are SIgA effector functions used to stimulate the immune response. Does not block SIgA-binding to its receptor (FCAR) on neutrophils, but it decreases SIgA-stimulated phosphorylation of cytoplasmic proteins, [...]


ensembl_gene_id: c5323
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: c5325
symbol: ytfQ
gene_biotype: protein_coding
description:
  ABC transporter Periplasmic binding protein ytfQ precursor; Escherichia coli K-12 ortholog: b4227; Escherichia coli O157:H7 ortholog: z5838.


ensembl_gene_id: c5326
symbol: ytfR
gene_biotype: protein_coding
description:
  Putative ATP-binding component of a transport system; Escherichia coli K-12 ortholog: b4228; Escherichia coli O157:H7 ortholog: z5839.


ensembl_gene_id: c5327
symbol: ytfT
gene_biotype: protein_coding
description:
  Hypothetical ABC transporter permease protein ytfT; Escherichia coli K-12 ortholog: b4230; Escherichia coli O157:H7 ortholog: z5840; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: c5328
symbol: yjfF
gene_biotype: protein_coding
description:
  Hypothetical ABC transporter permease protein yjfF; Escherichia coli K-12 ortholog: b4231; Escherichia coli O157:H7 ortholog: z5841; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: c5329
symbol: fbp
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphatase; Escherichia coli K-12 ortholog: b4232; Escherichia coli O157:H7 ortholog: z5842.


ensembl_gene_id: c5331
symbol: yjfG
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: c5332
symbol: yjgA
gene_biotype: protein_coding
description:
  Hypothetical protein yjgA; X96 protein; Escherichia coli K-12 ortholog: b4234; Escherichia coli O157:H7 ortholog: z5844; Belongs to the UPF0307 family.


ensembl_gene_id: c5335
symbol: cybC
gene_biotype: protein_coding
description:
  Soluble cytochrome b562 precursor; Electron-transport protein of unknown function. Belongs to the cytochrome b562 family.


ensembl_gene_id: c5336
symbol: nrdG
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: c5337
symbol: nrdD
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase; Escherichia coli K-12 ortholog: b4238; Escherichia coli O157:H7 ortholog: z5848.


ensembl_gene_id: c5338
symbol: treC
gene_biotype: protein_coding
description:
  Trehalose-6-phosphate hydrolase; Escherichia coli K-12 ortholog: b4239; Escherichia coli O157:H7 ortholog: z5849.


ensembl_gene_id: c5339
symbol: treB
gene_biotype: protein_coding
description:
  PTS system, trehalose-specific IIBC component; EIIBC-TRE; Escherichia coli K-12 ortholog: b4240; Escherichia coli O157:H7 ortholog: z5850.


ensembl_gene_id: c5340
symbol: treR
gene_biotype: protein_coding
description:
  Trehalose operon repressor; Escherichia coli K-12 ortholog: b4241; Escherichia coli O157:H7 ortholog: z5851.


ensembl_gene_id: c5341
symbol: mgtA
gene_biotype: protein_coding
description:
  Mg(2+) transport ATPase, P-type 1; Escherichia coli K-12 ortholog: b4242; Escherichia coli O157:H7 ortholog: z5853.


ensembl_gene_id: c5342
symbol: yjgF
gene_biotype: protein_coding
description:
  Protein yjgF; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis (By similarity); Belongs to the RutC family.


ensembl_gene_id: c5344
symbol: pyrI
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.


ensembl_gene_id: c5345
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase catalytic chain; Escherichia coli K-12 ortholog: b4245; Escherichia coli O157:H7 ortholog: z5856; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: c5347
symbol: c5347
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 16 to 482 of 482 are 89.93 pct identical to residues 1 to 467 of 467 from GenPept.129 : >emb|CAD06924.1| (AL627283) putative membrane protein [Salmonella enterica subsp. enterica serovar Typhi].


ensembl_gene_id: c5348
symbol: arcB-2
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.


ensembl_gene_id: c5350
symbol: arcA-2
gene_biotype: protein_coding
description:
  Putative arginine deiminase; Residues 7 to 407 of 407 are 47.79 pct identical to residues 10 to 416 of 418 from SwissProt.40 : >sp|P13981|ARCA_PSEAE Arginine deiminase (ADI) (Arginine dihydrolase) (AD).


ensembl_gene_id: c5354
symbol: yjgD
gene_biotype: protein_coding
description:
  Hypothetical protein yjgD; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: c5355
symbol: c5355
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 7 to 173 of 173 are 91.61 pct identical to residues 1 to 167 of 167 from SwissProt.40 : >sp|P39337|YJGM_ECOLI HYPOTHETICAL 18.6 KDA PROTEIN IN ARGI-VALS INTERGENIC REGION.


ensembl_gene_id: c5356
symbol: c5356
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 144 of 176 are 64.58 pct identical to residues 1 to 144 of 395 from GenPept.129 : >gb|AAL23293.1| (AE008910) putative inner membrane protein [Salmonella typhimurium LT2].


ensembl_gene_id: c5357
symbol: c5357
gene_biotype: protein_coding
description:
  Putative conserved protein; Residues 4 to 229 of 229 are 37.44 pct identical to residues 167 to 393 of 393 from MG1655 : b4257.


ensembl_gene_id: c5358
symbol: valS
gene_biotype: protein_coding
description:
  Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: c5359
symbol: holC
gene_biotype: protein_coding
description:
  DNA polymerase III, chi subunit; Escherichia coli K-12 ortholog: b4259; Escherichia coli O157:H7 ortholog: z5871.


ensembl_gene_id: c5360
symbol: pepA
gene_biotype: protein_coding
description:
  Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Required for plasmid ColE1 site-specific recombination but not in its aminopeptidase activity. Could act as a structural component of the putative nucleoprotein complex in which the Xer recombination reaction takes place (By similarity); Belongs to the peptidase M17 family.


ensembl_gene_id: c5362
symbol: yjgP
gene_biotype: protein_coding
description:
  Hypothetical protein yjgP; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.


ensembl_gene_id: c5363
symbol: yjgQ
gene_biotype: protein_coding
description:
  Hypothetical protein yjgQ; Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.


ensembl_gene_id: c5364
symbol: yjgR
gene_biotype: protein_coding
description:
  Hypothetical protein yjgR; Escherichia coli K-12 ortholog: b4263; Escherichia coli O157:H7 ortholog: z5875.


ensembl_gene_id: c5365
symbol: idnR
gene_biotype: protein_coding
description:
  L-idonate Regulatory protein; Escherichia coli K-12 ortholog: b4264; Escherichia coli O157:H7 ortholog: z4806.


ensembl_gene_id: c5366
symbol: idnT
gene_biotype: protein_coding
description:
  Gnt-II system L-idonate transporter; L-Ido transporter; Escherichia coli K-12 ortholog: b4265; Escherichia coli O157:H7 ortholog: z4770.


ensembl_gene_id: c5367
symbol: idnO
gene_biotype: protein_coding
description:
  Gluconate 5-dehydrogenase; Catalyzes the reduction of 5-keto-D-gluconate to D-gluconate, using either NADH or NADPH. Is likely involved in an L-idonate degradation pathway that allows E.coli to utilize L-idonate as the sole carbon and energy source. Is also able to catalyze the reverse reaction in vitro, but the D-gluconate oxidation by the enzyme can only proceed with NAD; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: c5369
symbol: idnK
gene_biotype: protein_coding
description:
  Thermosensitive gluconokinase; Escherichia coli K-12 ortholog: b4268; Escherichia coli O157:H7 ortholog: z4805.


ensembl_gene_id: c5370
symbol: yjgB
gene_biotype: protein_coding
description:
  Hypothetical zinc-type alcohol dehydrogenase-like protein yjgB; Escherichia coli K-12 ortholog: b4269; Escherichia coli O157:H7 ortholog: z5876.


ensembl_gene_id: c5371
symbol: c5371
gene_biotype: protein_coding
description:
  Prophage P4 integrase; Int(P4); Escherichia coli K-12 ortholog: b4271; Escherichia coli O157:H7 ortholog: z5890; Belongs to the 'phage' integrase family.


ensembl_gene_id: c5372
symbol: c5372
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 1022 of 1023 are 51.23 pct identical to residues 1 to 1041 of 1043 from GenPept.129 : >gb|AAK02783.1| (AE006106) unknown [Pasteurella multocida].


ensembl_gene_id: c5373
symbol: c5373
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 2 to 668 of 670 are 43.91 pct identical to residues 3 to 634 of 636 from GenPept.129 : >gb|AAK02782.1| (AE006106) unknown [Pasteurella multocida].


ensembl_gene_id: c5377
symbol: c5377
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 11 to 227 of 233 are 37.94 pct identical to residues 1 to 220 of 220 from GenPept.129 : >gb|AAK02781.1| (AE006106) unknown [Pasteurella multocida].


ensembl_gene_id: c5378
symbol: c5378
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 1090 of 1092 are 60.92 pct identical to residues 1 to 1088 of 1089 from GenPept.129 : >gb|AAK02780.1| (AE006106) unknown [Pasteurella multocida].


ensembl_gene_id: c5379
symbol: c5379
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 9 to 293 of 301 are 47.90 pct identical to residues 20 to 305 of 308 from GenPept.129 : >gb|AAM08019.1| (AY090559) hypothetical protein [Providencia rettgeri].


ensembl_gene_id: c5381
symbol: c5381
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 14 to 75 of 95 are 82.25 pct identical to residues 1 to 62 of 200 from GenPept.129 : >gb|AAL23316.1| (AE008911) putative inner membrane protein [Salmonella typhimurium LT2].


ensembl_gene_id: c5382
symbol: c5382
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 87 to 229 of 237 are 81.81 pct identical to residues 1 to 143 of 245 from GenPept.129 : >gb|AAL23321.1| (AE008912) putative inner membrane protein [Salmonella typhimurium LT2].


ensembl_gene_id: c5383
symbol: c5383
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 46 to 199 of 223 are 30.57 pct identical to residues 20 to 172 of 188 from GenPept.129 : >dbj|BAB06239.1| (AP001515) transposase related protein (20) [Bacillus halodurans].


ensembl_gene_id: c5385
symbol: c5385
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 6 to 106 of 109 are 70.29 pct identical to residues 143 to 243 of 245 from GenPept.129 : >gb|AAL23321.1| (AE008912) putative inner membrane protein [Salmonella typhimurium LT2].


ensembl_gene_id: c5387
symbol: c5387
gene_biotype: protein_coding
description:
  Hypothetical protein yjhS precursor; Escherichia coli K-12 ortholog: b4309; Escherichia coli O157:H7 ortholog: z5905.


ensembl_gene_id: c5389
symbol: nanC
gene_biotype: protein_coding
description:
  Hypothetical protein yjhA precursor; Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria. NanC proteins form high-conductance channels which are open at low membrane potentials and which have a weak anion selectivity (By similarity).


ensembl_gene_id: c5392
symbol: fimE
gene_biotype: protein_coding
description:
  Type 1 fimbriae Regulatory protein fimE; FimE is one of the 2 regulatory proteins which control the phase variation of type 1 fimbriae in E.coli. These proteins mediate the periodic inversion of a 300bp DNA segment that harbors the promoter for the fimbrial structural gene, fimA. FimE switches fimA off (By similarity).


ensembl_gene_id: c5393
symbol: fimA
gene_biotype: protein_coding
description:
  Type-1 fimbrial protein, A chain precursor; Type-1A pilin; Escherichia coli K-12 ortholog: b4314; Escherichia coli O157:H7 ortholog: z5912.


ensembl_gene_id: c5394
symbol: fimI
gene_biotype: protein_coding
description:
  Fimbrin-like protein fimI precursor; Escherichia coli K-12 ortholog: b4315; Escherichia coli O157:H7 ortholog: z5913.


ensembl_gene_id: c5395
symbol: fimC
gene_biotype: protein_coding
description:
  Chaperone protein fimC precursor; Required for the biogenesis of type 1 fimbriae. Binds and interact with FimH (By similarity); Belongs to the periplasmic pilus chaperone family.


ensembl_gene_id: c5396
symbol: fimD
gene_biotype: protein_coding
description:
  Outer membrane usher protein fimD precursor; Escherichia coli K-12 ortholog: b4317; Escherichia coli O157:H7 ortholog: z5915.


ensembl_gene_id: c5397
symbol: fimF
gene_biotype: protein_coding
description:
  FimF protein precursor; Escherichia coli K-12 ortholog: b4318; Escherichia coli O157:H7 ortholog: z5916.


ensembl_gene_id: c5399
symbol: fimG
gene_biotype: protein_coding
description:
  FimG protein precursor; Escherichia coli K-12 ortholog: b4319; Escherichia coli O157:H7 ortholog: z5917.


ensembl_gene_id: c5400
symbol: fimH
gene_biotype: protein_coding
description:
  FimH protein precursor; Escherichia coli K-12 ortholog: b4320; Escherichia coli O157:H7 ortholog: z5918.


ensembl_gene_id: c5401
symbol: gntP
gene_biotype: protein_coding
description:
  High-affinity gluconate transporter; Gluconate permease 3; Escherichia coli K-12 ortholog: b4321; Escherichia coli O157:H7 ortholog: z5919.


ensembl_gene_id: c5402
symbol: uxuA
gene_biotype: protein_coding
description:
  Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.


ensembl_gene_id: c5403
symbol: uxuB
gene_biotype: protein_coding
description:
  D-mannonate oxidoreductase; Escherichia coli K-12 ortholog: b4323; Escherichia coli O157:H7 ortholog: z5921; Belongs to the mannitol dehydrogenase family.


ensembl_gene_id: c5404
symbol: uxuR
gene_biotype: protein_coding
description:
  Uxu operon transcriptional regulator; Escherichia coli K-12 ortholog: b4324; Escherichia coli O157:H7 ortholog: z5922.


ensembl_gene_id: c5405
symbol: yjiD
gene_biotype: protein_coding
description:
  Hypothetical protein yjiD; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.


ensembl_gene_id: c5406
symbol: c5406
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 113 of 113 are 95.57 pct identical to residues 424 to 536 of 536 from GenPept.129 : >gb|AAL61895.1| (AF289032) putative phosphoenolpyruvate-protein phosphoryltransferase PptE [Escherichia coli].


ensembl_gene_id: c5407
symbol: yjiE
gene_biotype: protein_coding
description:
  Hypothetical transcriptional regulator yjiE; Escherichia coli K-12 ortholog: b4327; Escherichia coli O157:H7 ortholog: z5926; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: c5408
symbol: iadA
gene_biotype: protein_coding
description:
  Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.


ensembl_gene_id: c5409
symbol: yjiG
gene_biotype: protein_coding
description:
  Hypothetical protein yjiG; Escherichia coli K-12 ortholog: b4329; Escherichia coli O157:H7 ortholog: z5928.


ensembl_gene_id: c5410
symbol: yjiH
gene_biotype: protein_coding
description:
  Hypothetical protein yjiH; Escherichia coli K-12 ortholog: b4330; Escherichia coli O157:H7 ortholog: z5929.


ensembl_gene_id: c5414
symbol: yjiJ
gene_biotype: protein_coding
description:
  Hypothetical protein yjiJ; Escherichia coli K-12 ortholog: b4332; Escherichia coli O157:H7 ortholog: z5933.


ensembl_gene_id: c5415
symbol: yjiK
gene_biotype: protein_coding
description:
  Hypothetical protein yjiK; Escherichia coli K-12 ortholog: b4333; Escherichia coli O157:H7 ortholog: z5934; Belongs to the YjiK family.


ensembl_gene_id: c5416
symbol: c5416
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 80 of 85 are 87.50 pct identical to residues 1 to 80 of 88 from GenPept.129 : >dbj|BAB38719.1| (AP002569) hypothetical protein [Escherichia coli O157:H7].


ensembl_gene_id: c5417
symbol: yjiL
gene_biotype: protein_coding
description:
  Hypothetical protein yjiL; Escherichia coli K-12 ortholog: b4334; Escherichia coli O157:H7 ortholog: z5936.


ensembl_gene_id: c5418
symbol: yjiM
gene_biotype: protein_coding
description:
  Hypothetical protein yjiM; Escherichia coli K-12 ortholog: b4335; Escherichia coli O157:H7 ortholog: z5937.


ensembl_gene_id: c5419
symbol: yjiN
gene_biotype: protein_coding
description:
  Hypothetical protein yjiN; Escherichia coli K-12 ortholog: b4336; Escherichia coli O157:H7 ortholog: z5938.


ensembl_gene_id: c5420
symbol: yfcI
gene_biotype: protein_coding
description:
  Hypothetical protein yfcI; Escherichia coli K-12 ortholog: b2305; Escherichia coli O157:H7 ortholog: z5940.


ensembl_gene_id: c5421
symbol: c5421
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 43 to 734 of 739 are 65.23 pct identical to residues 1 to 697 of 702 from GenPept.129 : >gb|AAM05803.1| (AE010933) conserved hypothetical protein [Methanosarcina acetivorans str. C2A].


ensembl_gene_id: c5422
symbol: yjiW
gene_biotype: protein_coding
description:
  Hypothetical protein yjiW; Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease Lon. Belongs to the SymE family.


ensembl_gene_id: c5424
symbol: c5424
gene_biotype: protein_coding
description:
  Putative restriction modification enzyme M subunit; Methylase; Escherichia coli O157:H7 ortholog: z5947.


ensembl_gene_id: c5425
symbol: c5425
gene_biotype: protein_coding
description:
  Putative restriction modification enzyme R subunit; Endonuclease; Escherichia coli O157:H7 ortholog: z5948.


ensembl_gene_id: c5427
symbol: yjiA
gene_biotype: protein_coding
description:
  Hypothetical protein yjiA; Escherichia coli K-12 ortholog: b4352; Escherichia coli O157:H7 ortholog: z5951.


ensembl_gene_id: c5428
symbol: yjiX
gene_biotype: protein_coding
description:
  Hypothetical protein yjiX; Escherichia coli K-12 ortholog: b4353; Escherichia coli O157:H7 ortholog: z5952; To E.coli YbdD.


ensembl_gene_id: c5429
symbol: yjiY
gene_biotype: protein_coding
description:
  Hypothetical protein yjiY; Escherichia coli K-12 ortholog: b4354; Escherichia coli O157:H7 ortholog: z5953.


ensembl_gene_id: c5430
symbol: tsr
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein I; MCP-I; Escherichia coli K-12 ortholog: b4355; Escherichia coli O157:H7 ortholog: z5955.


ensembl_gene_id: c5431
symbol: c5431
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 1 to 422 of 423 are 42.31 pct identical to residues 1 to 423 of 428 from GenPept.129 : >gb|AAL95452.1| (AE010631) C4-dicarboxylate transporter large subunit [Fusobacterium nucleatum subsp. nucleatum ATCC 25586].


ensembl_gene_id: c5432
symbol: c5432
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 19 to 144 of 157 are 29.92 pct identical to residues 7 to 133 of 174 from GenPept.129 : >emb|CAC26718.1| (AX066981) RXN02955 [Corynebacterium glutamicum].


ensembl_gene_id: c5433
symbol: c5433
gene_biotype: protein_coding
description:
  Putative C4-dicarboxylate-binding periplasmic protein; Residues 4 to 268 of 269 are 32.33 pct identical to residues 58 to 323 of 325 from GenPept.129 : >emb|CAC49506.1| (AL603646) putative C4-dicarboxylate transporter periplasmic solute-binding protein precursor [Sinorhizobium meliloti].


ensembl_gene_id: c5436
symbol: yjjM
gene_biotype: protein_coding
description:
  Hypothetical protein yjjM; Escherichia coli K-12 ortholog: b4357; Escherichia coli O157:H7 ortholog: z5957.


ensembl_gene_id: c5438
symbol: mdoB
gene_biotype: protein_coding
description:
  Phosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family.


ensembl_gene_id: c5439
symbol: yjjA
gene_biotype: protein_coding
description:
  Hypothetical protein yjjA precursor; Protein P-18; Escherichia coli K-12 ortholog: b4360; Escherichia coli O157:H7 ortholog: z5960.


ensembl_gene_id: c5440
symbol: dnaC
gene_biotype: protein_coding
description:
  DNA replication protein dnaC; This protein is required for chromosomal replication. It forms, in concert with DnaB protein and other prepriming proteins DnaT, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' (By similarity).


ensembl_gene_id: c5441
symbol: dnaT
gene_biotype: protein_coding
description:
  Primosomal protein I; This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.


ensembl_gene_id: c5443
symbol: yjjP
gene_biotype: protein_coding
description:
  Hypothetical protein yjjP; Escherichia coli K-12 ortholog: b4364; Escherichia coli O157:H7 ortholog: z5964.


ensembl_gene_id: c5444
symbol: yjjQ
gene_biotype: protein_coding
description:
  Hypothetical protein yjjQ; Escherichia coli K-12 ortholog: b4365; Escherichia coli O157:H7 ortholog: z5966.


ensembl_gene_id: c5445
symbol: bglJ
gene_biotype: protein_coding
description:
  Transcriptional activator protein bglJ; Escherichia coli K-12 ortholog: b4366; Escherichia coli O157:H7 ortholog: z5967.


ensembl_gene_id: c5446
symbol: fhuF
gene_biotype: protein_coding
description:
  Ferric iron reductase protein fhuF; Escherichia coli K-12 ortholog: b4367; Escherichia coli O157:H7 ortholog: z5968.


ensembl_gene_id: c5447
symbol: c5447
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 38 to 115 of 115 are 96.15 pct identical to residues 1 to 78 of 78 from SwissProt.40 : >sp|P55914|YJJZ_ECOLI Hypothetical protein yjjZ.


ensembl_gene_id: c5450
symbol: yjjT
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: c5452
symbol: holD
gene_biotype: protein_coding
description:
  DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.


ensembl_gene_id: c5453
symbol: rimI
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: c5454
symbol: yjjG
gene_biotype: protein_coding
description:
  Hypothetical protein yjjG; Escherichia coli K-12 ortholog: b4374; Escherichia coli O157:H7 ortholog: z5975.


ensembl_gene_id: c5456
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: c5457
symbol: osmY
gene_biotype: protein_coding
description:
  Osmotically inducible protein Y precursor; Escherichia coli K-12 ortholog: b4376; Escherichia coli O157:H7 ortholog: z5977.


ensembl_gene_id: c5460
symbol: yjjU
gene_biotype: protein_coding
description:
  Hypothetical protein yjjU; Escherichia coli K-12 ortholog: b4377; Escherichia coli O157:H7 ortholog: z5979.


ensembl_gene_id: c5461
symbol: yjjV
gene_biotype: protein_coding
description:
  Putative deoxyribonuclease yjjV; Escherichia coli K-12 ortholog: b4378; Escherichia coli O157:H7 ortholog: z5980.


ensembl_gene_id: c5462
symbol: yjjW
gene_biotype: protein_coding
description:
  Hypothetical protein yjjW; Escherichia coli K-12 ortholog: b4379; Escherichia coli O157:H7 ortholog: z5981.


ensembl_gene_id: c5463
symbol: yjjI
gene_biotype: protein_coding
description:
  Hypothetical protein yjjI; Escherichia coli K-12 ortholog: b4380; Escherichia coli O157:H7 ortholog: z5982.


ensembl_gene_id: c5465
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: c5466
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: c5467
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: c5468
symbol: deoD
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; Escherichia coli K-12 ortholog: b4384; Escherichia coli O157:H7 ortholog: z5986.


ensembl_gene_id: c5471
symbol: lplA
gene_biotype: protein_coding
description:
  Lipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.


ensembl_gene_id: c5473
symbol: serB
gene_biotype: protein_coding
description:
  Phosphoserine phosphatase; Escherichia coli K-12 ortholog: b4388; Escherichia coli O157:H7 ortholog: z5989.


ensembl_gene_id: c5474
symbol: sms
gene_biotype: protein_coding
description:
  DNA repair protein radA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: c5475
symbol: nadR
gene_biotype: protein_coding
description:
  Transcriptional regulator nadR; Escherichia coli K-12 ortholog: b4390; Escherichia coli O157:H7 ortholog: z5991.


ensembl_gene_id: c5476
symbol: c5476
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 32 to 135 of 136 are 36.19 pct identical to residues 4 to 108 of 110 from GenPept.129 : >gb|AAF96372.1| (AE004379) hypothetical protein [Vibrio cholerae].


ensembl_gene_id: c5477
symbol: c5477
gene_biotype: protein_coding
description:
  Hypothetical protein; Residues 16 to 85 of 94 are 38.57 pct identical to residues 6 to 75 of 84 from GenPept.129 : >gb|AAL22872.1| (AE008888) putative bacterial regulatory protein, merR family [Salmonella typhimurium LT2].


ensembl_gene_id: c5478
symbol: yjjK
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein yjjK; A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.


ensembl_gene_id: c5479
symbol: slt
gene_biotype: protein_coding
description:
  Soluble lytic murein transglycosylase precursor; Escherichia coli K-12 ortholog: b4392; Escherichia coli O157:H7 ortholog: z5994.


ensembl_gene_id: c5480
symbol: trpR
gene_biotype: protein_coding
description:
  Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.


ensembl_gene_id: c5481
symbol: yjjX
gene_biotype: protein_coding
description:
  Hypothetical protein yjjX; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: c5482
symbol: gpmB
gene_biotype: protein_coding
description:
  Probable phosphoglycerate mutase 2; Escherichia coli K-12 ortholog: b4395; Escherichia coli O157:H7 ortholog: z5997; Belongs to the phosphoglycerate mutase family. GpmB subfamily.


ensembl_gene_id: c5483
symbol: rob
gene_biotype: protein_coding
description:
  Right origin-binding protein; Escherichia coli K-12 ortholog: b4396; Escherichia coli O157:H7 ortholog: z5999.


ensembl_gene_id: c5485
symbol: creB
gene_biotype: protein_coding
description:
  Transcriptional Regulatory protein creB; Escherichia coli K-12 ortholog: b4398; Escherichia coli O157:H7 ortholog: z6001.


ensembl_gene_id: c5486
symbol: creC
gene_biotype: protein_coding
description:
  Sensor protein creC; Escherichia coli K-12 ortholog: b4399; Escherichia coli O157:H7 ortholog: z6002.


ensembl_gene_id: c5487
symbol: creD
gene_biotype: protein_coding
description:
  Inner membrane protein creD; Escherichia coli K-12 ortholog: b4400; Escherichia coli O157:H7 ortholog: z6003.


ensembl_gene_id: c5488
symbol: arcA
gene_biotype: protein_coding
description:
  Aerobic respiration control protein arcA; Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions. It also may be involved in the osmoregulation of envelope proteins. When activated by ArcB, it negatively regulates the expression of genes of aerobic function. Activates the transcription of the plfB operon by binding to its promoter (By similarity).


ensembl_gene_id: c5489
symbol: yjjY
gene_biotype: protein_coding
description:
  Hypothetical protein yjjY; Escherichia coli K-12 ortholog: b4402; Escherichia coli O157:H7 ortholog: z6005.


ensembl_gene_id: c5490
symbol: lasT
gene_biotype: protein_coding
description:
  Hypothetical tRNA/rRNA methyltransferase lasT; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: c5493
symbol: fruL
gene_biotype: protein_coding
description:
  Very hypothetical fruR/shl operon leader peptide; Escherichia coli K-12 ortholog: b0079; Escherichia coli O157:H7 ortholog: z0089.


ensembl_gene_id: c5495
symbol: pheM
gene_biotype: protein_coding
description:
  Phenylalanyl-tRNA synthetase operon leader peptide; PheST attenuator peptide; Escherichia coli K-12 ortholog: b1715.


ensembl_gene_id: c5622
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: c5623
symbol: fdnG
gene_biotype: protein_coding
description:
  Formate dehydrogenase, nitrate-inducible, major subunit; Escherichia coli K-12 ortholog: b1474; Escherichia coli O157:H7 ortholog: z2236.


ensembl_gene_id: c5624
symbol: fdoG
gene_biotype: protein_coding
description:
  Formate dehydrogenase-O, major subunit; Escherichia coli K-12 ortholog: b3894; Escherichia coli O157:H7 ortholog: z5436.


ensembl_gene_id: c5625
symbol: fdhF
gene_biotype: protein_coding
description:
  Formate dehydrogenase H; Escherichia coli K-12 ortholog: b4079; Escherichia coli O157:H7 ortholog: z5678; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


