# geneInfo

ensembl_gene_id: SO_0003
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification system GTPase subunit MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: SO_0004
symbol: yidC
gene_biotype: protein_coding
description:
  Membrane protein insertase YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: SO_0005
symbol: yidD
gene_biotype: protein_coding
description:
  Membrane insertion associated protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: SO_0006
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein RnpA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: SO_0008
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.


ensembl_gene_id: SO_0009
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]


ensembl_gene_id: SO_0010
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: SO_0011
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase B subunit GyrB; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SO_0019
symbol: tusA
gene_biotype: protein_coding
description:
  tRNA 2-thiouridine synthesizing protein TusA; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: SO_0020
symbol: fadA
gene_biotype: protein_coding
description:
  Aerobic fatty oxidation complex 3-ketoacyl-CoA thiolase beta subunit FadA; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: SO_0021
symbol: fadB
gene_biotype: protein_coding
description:
  Aerobic fatty oxidation complex 3-hydroxyacyl-CoA epimerase alpha subunit FadB; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: SO_0024
symbol: trkH
gene_biotype: protein_coding
description:
  Potassium uptake transporter TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: SO_0028
symbol: trkI
gene_biotype: protein_coding
description:
  Potassium uptake transporter TrkI; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: SO_0030
symbol: rsmB
gene_biotype: protein_coding
description:
  16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: SO_0031
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase Fmt; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: SO_0032
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase Def; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: SO_0037
symbol: rimN
gene_biotype: protein_coding
description:
  Threonylcarbamoyladenosine t(6)A tRNA modification protein RimN; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: SO_0038
symbol: hemF
gene_biotype: protein_coding
description:
  Aerobic coproporphyrinogen III oxidase HemF; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: SO_0040
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: SO_0049
symbol: gpmA
gene_biotype: protein_coding
description:
  2,3-bisphosphoglycerate-independent phosphoglycerate mutase GpmA; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: SO_0052
symbol: secB
gene_biotype: protein_coding
description:
  Protein export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: SO_0053
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase (NADP+) GpsA; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: SO_0059
symbol: kdpE
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, KDP operon response regulator KdpE; Two component signal transduction system controlling the osmosenstive K+ channel response regulator KdpE.


ensembl_gene_id: SO_0060
symbol: kdpD
gene_biotype: protein_coding
description:
  Two component signal transduction system controlling the osmosenstive K+ channel histidine kinase KdpD.


ensembl_gene_id: SO_0084
symbol: mtnC
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthio-1-phosphopentane phosphatase MtnC; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: SO_0101
symbol: fdnG
gene_biotype: protein_coding
description:
  Nitrate-inducible formate dehydrogenase molybdopterin-binding subunit FdnG; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SO_0102
symbol: fdnH
gene_biotype: protein_coding
description:
  Nitrate-inducible formate dehydrogenase iron-sulfur subunit FdnH; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: SO_0104
symbol: fdhE
gene_biotype: protein_coding
description:
  Nitrate-inducible formate dehydrogenase chaperone FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: SO_0105
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA selenium transferase SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: SO_0107
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase assembly/maturation protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: SO_0131
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate-pyruvate lyase UbiC; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: SO_0132
symbol: SO_0132
gene_biotype: protein_coding
description:
  Periplasmic FliL-like protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: SO_0134
symbol: rlmF
gene_biotype: protein_coding
description:
  23S rRNA (adenine1618-N6)-methyltransferase RlmF; Specifically methylates the adenine in position 1618 of 23S rRNA.


ensembl_gene_id: SO_0138
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: SO_0141
symbol: SO_0141
gene_biotype: protein_coding
description:
  Nitrate/nitrite-responsive bifunctional diguanylate cyclase/phosphodiesterase with PAS sensory domain.


ensembl_gene_id: SO_0142
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase RibB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: SO_0157
symbol: SO_0157
gene_biotype: protein_coding
description:
  Proton:glutamate symporter DAACS family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SO_0162
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase PckA; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: SO_0163
symbol: hslO
gene_biotype: protein_coding
description:
  Redox regulated chaperone HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: SO_0167
symbol: gspE
gene_biotype: protein_coding
description:
  T2aSS secretion system assembly ATPase GspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: SO_0174
symbol: gspL
gene_biotype: protein_coding
description:
  T2aSSsecretion system inner membrane platform protein GspL; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: SO_0175
symbol: gspM
gene_biotype: protein_coding
description:
  T2aSS secretion system inner membrane platform protein GspM; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: SO_0191
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2')5'-bisphosphate nucleotidase CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: SO_0194
symbol: SO_0194
gene_biotype: protein_coding
description:
  Bifunctional lysophospholipid transporter-2-acyl glycerophosphoethanolamine acyl transferase/acyl ACP synthetase.


ensembl_gene_id: SO_0195
symbol: selU
gene_biotype: protein_coding
description:
  Selenophosphate-dependent tRNA 2-selenouridine synthase SelU; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: SO_0206
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase TrmA; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: SO_0214
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: SO_0217
symbol: tufB
gene_biotype: protein_coding
description:
  Translation elongation factor Tu TufB; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: SO_0218
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: SO_0219
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: SO_0220
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11 RplK; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: SO_0221
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1 RplA; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: SO_0222
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: SO_0223
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12 RplL; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: SO_0224
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta subunit RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SO_0225
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' subunit RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SO_0227
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7 RpsG; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: SO_0228
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor G FusA; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/E [...]


ensembl_gene_id: SO_0229
symbol: tufA
gene_biotype: protein_coding
description:
  Translation elongation factor Tu TufA; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: SO_0230
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10 RpsJ; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: SO_0231
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3 RplC; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: SO_0232
symbol: rplD
gene_biotype: protein_coding
description:
  50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.


ensembl_gene_id: SO_0233
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23 RplW; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: SO_0234
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2 RplB; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: SO_0235
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19 RpsS; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: SO_0236
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22 RplV; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).


ensembl_gene_id: SO_0237
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3 RpsC; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: SO_0238
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16 RplP; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: SO_0240
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein S17 RpsQ; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: SO_0241
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14 RplN; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: SO_0242
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24 RplX; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: SO_0243
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5 RplE; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: SO_0244
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14 RpsN; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: SO_0245
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8 RpsH; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: SO_0246
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: SO_0247
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18 RplR; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: SO_0248
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5 RpsE; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: SO_0250
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15 RplO; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: SO_0251
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: SO_0253
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13 RpsM; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: SO_0254
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11 RpsK; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: SO_0255
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4 RpsD; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: SO_0256
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: SO_0259
symbol: ccmE
gene_biotype: protein_coding
description:
  ABC-type heme export system chaperone component CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity); Belongs to the CcmE/CycJ family.


ensembl_gene_id: SO_0260
symbol: ccmD
gene_biotype: protein_coding
description:
  ABC-type heme export system CcmE-interacting component CcmD; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: SO_0261
symbol: ccmC
gene_biotype: protein_coding
description:
  ABC-type heme export system permease component 2 CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: SO_0262
symbol: ccmB
gene_biotype: protein_coding
description:
  ABC-type heme export system permease component 1 CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: SO_0263
symbol: ccmA
gene_biotype: protein_coding
description:
  ABC-type heme export system ATPase component CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: SO_0272
symbol: pncC
gene_biotype: protein_coding
description:
  Nicotinamide deamidase PncC; One of the key enzymes of the pyridine nucleotide cycle which permits cells to recycle the by products of NAD consumption back to NAD. Has no activity on NAD, NADP, nicotinamide or nicotinamide riboside.


ensembl_gene_id: SO_0274
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase Ppc; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.


ensembl_gene_id: SO_0275
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase ArgC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: SO_0276
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase ArgB; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: SO_0277
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase ArgF; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.


ensembl_gene_id: SO_0278
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: SO_0286
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: SO_0287
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase AroB; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: SO_0293
symbol: gph
gene_biotype: protein_coding
description:
  2-phosphoglycolate phosphatase Gph; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: SO_0294
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase TrpS; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: SO_0298
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: SO_0299
symbol: SO_0299
gene_biotype: protein_coding
description:
  Predicted endonuclease distantly related to archael Holliday junction resolvase TIGR00252 family; Belongs to the UPF0102 family.


ensembl_gene_id: SO_0301
symbol: rsmI
gene_biotype: protein_coding
description:
  16S rRNA (cytidine1402-2'-O)-methyltransferase RsmI; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: SO_0313
symbol: potE
gene_biotype: protein_coding
description:
  Putrescine:ornithine antiporter PotE; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.


ensembl_gene_id: SO_0330
symbol: selO
gene_biotype: protein_coding
description:
  Uncharacterized protein UPF0061 family; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).


ensembl_gene_id: SO_0332
symbol: rdoA
gene_biotype: protein_coding
description:
  Serine/threonine protein kinase RdoA; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: SO_0335
symbol: zapB
gene_biotype: protein_coding
description:
  Septal ring assembly factor ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: SO_0342
symbol: prpF
gene_biotype: protein_coding
description:
  2-methyl aconitate cis-trans isomerase PrpF; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle II (propionate degradation route). PrpF catalyzes the cis-trans isomerization of 2-methyl-aconitate through a base-catalyzed proton abstraction coupled with a rotation about C2-C3 bond of 2-methyl-aconitate.


ensembl_gene_id: SO_0343
symbol: acnD
gene_biotype: protein_coding
description:
  2-methyl citrate dehydratase Fe-S dependent AcnD; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle II (propionate degradation route). In vivo under anaerobic conditions, AcnD catalyzes the stereospecific dehydration of (2S,3S)-methylcitrate (2-MC) to yield the trans isomer of 2-methyl-aconitate (2-MCA). AcnD can also accept citrate and cis- aconitate, but with a lower efficiency. 2-methylisocitrate and isocitrate are not substrates.


ensembl_gene_id: SO_0344
symbol: prpC
gene_biotype: protein_coding
description:
  2-methylcitrate synthase PrpC; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle II (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Catalyzes the condensation of oxaloacetate with acetyl-CoA (By similarity).


ensembl_gene_id: SO_0345
symbol: prpB
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase PrpB; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate.


ensembl_gene_id: SO_0359
symbol: spoT
gene_biotype: protein_coding
description:
  Bifunctional ppGpp phosphohydrolase/GTP diphosphokinase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: SO_0360
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase omega subunit RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: SO_0380
symbol: hsdR
gene_biotype: protein_coding
description:
  Type I restriction-modification system restriction endonuclease cleavage subunit HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: SO_0393
symbol: fis
gene_biotype: protein_coding
description:
  Global transcriptional activator Fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: SO_0394
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: SO_0395
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase PrmA; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: SO_0401
symbol: SO_0401
gene_biotype: protein_coding
description:
  Putative NADPH-dependent quinone oxidoreductase; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: SO_0405
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: SO_0407
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlB; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: SO_0411
symbol: yacG
gene_biotype: protein_coding
description:
  Putative zinc-binding protein of unknown function DUF329 YacG; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: SO_0412
symbol: yacF
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1342 YacF; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: SO_0413
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: SO_0414
symbol: pilD
gene_biotype: protein_coding
description:
  Type IV prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: SO_0424
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: SO_0425
symbol: aceF
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: SO_0435
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase HemE; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: SO_0437
symbol: pdeB
gene_biotype: protein_coding
description:
  Signalling protein with PAS GGDEF and EAL domains; Affects motility and biofilm formation, and is linked to the regulation of sulfate uptake and assimilation.


ensembl_gene_id: SO_0438
symbol: SO_0438
gene_biotype: protein_coding
description:
  Oxidoreductase short chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SO_0468
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase UbiA; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: SO_0479
symbol: sirA
gene_biotype: protein_coding
description:
  Sulfite reductase octaheme cytochrome c SirA; Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process. Required for sulfite respiration under anaerobic growth conditions. Does not contribute to nitrite reduction.


ensembl_gene_id: SO_0500
symbol: SO_0500
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein; Chemotaxis signal transduction system methyl accepting sensory transducer with 4HB_MCP sensory domain.


ensembl_gene_id: SO_0506
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase UbiD; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: SO_0511
symbol: accB
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase biotin carboxyl carrier protein AccB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: SO_0512
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase type II AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: SO_0520
symbol: SO_0520
gene_biotype: protein_coding
description:
  Heavy metal efflux pump permease component CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_0522
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive ion channel protein MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: SO_0529
symbol: trpI
gene_biotype: protein_coding
description:
  Transcriptional activator of tryptophan biosynthesis TrpI; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_0533
symbol: arsC2
gene_biotype: protein_coding
description:
  Thioredoxin-coupled cytoplasmic arsenate reductase ArsC2; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: SO_0538
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase (NAD+) GapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SO_0545
symbol: SO_0545
gene_biotype: protein_coding
description:
  Two component signal transduction system response regulator with diguanylate cyclase/phosphodiesterase acitivity.


ensembl_gene_id: SO_0548
symbol: SO_0548
gene_biotype: protein_coding
description:
  Histone-like DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: SO_0558
symbol: smtA
gene_biotype: protein_coding
description:
  SAM-dependent methyltransferase SmtA; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: SO_0567
symbol: plsC
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase PlsC; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: SO_0568
symbol: rraB
gene_biotype: protein_coding
description:
  Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: SO_0575
symbol: rapA
gene_biotype: protein_coding
description:
  RNA polymerase-associated helicase RapA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: SO_0582
symbol: tpmT
gene_biotype: protein_coding
description:
  Thiopurine S-methyltransferase TpmT; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: SO_0590
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase Psd; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: SO_0591
symbol: rsgA
gene_biotype: protein_coding
description:
  30S ribosome assembly GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: SO_0592
symbol: orn
gene_biotype: protein_coding
description:
  3'-5' oligoribonuclease Orn; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: SO_0598
symbol: yjeF
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole kinase-related protein YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to  [...]


ensembl_gene_id: SO_0601
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: SO_0602
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase MiaA; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: SO_0603
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding pleiotrophic regulator Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: SO_0604
symbol: hflX
gene_biotype: protein_coding
description:
  50S ribosome assembly GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: SO_0605
symbol: hflK
gene_biotype: protein_coding
description:
  Membrane anchored FtsH modulator component 1 HflK; HflC and HflK could encode or regulate a protease.


ensembl_gene_id: SO_0608
symbol: petA
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase FeS subunit PetA; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: SO_0609
symbol: petB
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase cytochrome b subunit PetB; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: SO_0617
symbol: argD
gene_biotype: protein_coding
description:
  Bifunctional acetylornithine aminotransferase/succinyl-diaminopimelate aminotransferase/succinylornithine transaminase ArgD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: SO_0619
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase AstD; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: SO_0627
symbol: ligT
gene_biotype: protein_coding
description:
  2'-5' RNA ligase LigT; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: SO_0633
symbol: mrcB
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B MrcB; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: SO_0695
symbol: SO_0695
gene_biotype: protein_coding
description:
  Potassium efflux protein CPA2 family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: SO_0696
symbol: dsbD
gene_biotype: protein_coding
description:
  Protein-disulfide reductase DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: SO_0702
symbol: bfe
gene_biotype: protein_coding
description:
  Multidrug and toxin efflux protein MATE family; Flavin adenine dinucleotide (FAD) transporter that facilitates export of flavin electron shuttles.


ensembl_gene_id: SO_0703
symbol: groES
gene_biotype: protein_coding
description:
  10 kDa chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: SO_0704
symbol: groEL
gene_biotype: protein_coding
description:
  60 kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: SO_0705
symbol: hipB
gene_biotype: protein_coding
description:
  Toxin-antitoxin system antidote transcriptional repressor Xre family; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate toxin HipA; overexpression in wild-type or a hipAB deletion temporarily inhibits cell growth. Binds operator DNA; in the ternary phosphoserine-HipA-HipB-DNA complex the DNA is bent about 125 degrees.


ensembl_gene_id: SO_0706
symbol: hipA
gene_biotype: protein_coding
description:
  Toxin-antitoxin system toxin HipA family; Toxic component of a type II toxin-antitoxin (TA) system; overexpression in wild-type temporarily inhibits cell growth, overexpression in a hipAB deletion leads to acute growth inhibition. The toxic effect of HipA is neutralized by its cognate antitoxin HipB. In the ternary phosphoserine-HipA-HipB-DNA complex the DNA is bent about 125 degrees; all HipA in the crystallized ternary complex is phosphorylated. In E.coli phosphorylation of HipA is thought to release HipB from the HipA-HipB-DNA complex, suggesting the complex functions differently in [...]


ensembl_gene_id: SO_0725
symbol: katG
gene_biotype: protein_coding
description:
  Bifunctional catalase/peroxidase HPI KatG; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: SO_0756
symbol: aroG
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: SO_0769
symbol: argR
gene_biotype: protein_coding
description:
  Arginine-responsive transcriptional repressor of arginine metabolism ArgR; Regulates arginine biosynthesis genes.


ensembl_gene_id: SO_0770
symbol: mdh
gene_biotype: protein_coding
description:
  NAD dependent malate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate.


ensembl_gene_id: SO_0774
symbol: ygfA
gene_biotype: protein_coding
description:
  5-formyltetrahydrofolate cyclo-ligase YgfA; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: SO_0775
symbol: zapA
gene_biotype: protein_coding
description:
  Cell division protein interacting with FtsZ ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: SO_0780
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system carrier of aminomethyl moiety GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: SO_0781
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase (decarboxylating) GcvP; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: SO_0810
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: SO_0811
symbol: rihA
gene_biotype: protein_coding
description:
  Pyrimidine-specific ribonucleoside hydrolase RihA; Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.


ensembl_gene_id: SO_0817
symbol: metR
gene_biotype: protein_coding
description:
  Transcription regulator of methionine biosynthesis MetR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_0818
symbol: metE
gene_biotype: protein_coding
description:
  B12-independent 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: SO_0820
symbol: macA
gene_biotype: protein_coding
description:
  ABC-type macrolide export systemMFP component MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_0821
symbol: macB
gene_biotype: protein_coding
description:
  ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: SO_0827
symbol: SO_0827
gene_biotype: protein_coding
description:
  Lactate transport protein LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: SO_0828
symbol: rsmC
gene_biotype: protein_coding
description:
  16S rRNA (guanine1207-N2)-methyltransferase RsmC; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: SO_0832
symbol: rsmE
gene_biotype: protein_coding
description:
  16S rRNA (uracil1498-N3)-methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: SO_0842
symbol: fusB
gene_biotype: protein_coding
description:
  Translation elongation factor G FusA-like protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase f [...]


ensembl_gene_id: SO_0845
symbol: napB
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase cytochrome c subunit NapB; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from the membrane-anchored tetraheme c-type CymA protein and transfers these to NapA subunit, thus allowing electron flow between membrane and periplasm. Not essential for nitrate reduction but confers advantage to the organism when grown on nitrate and thereby a fitness gain in utilizing nitrate. Belongs to the NapB family.


ensembl_gene_id: SO_0848
symbol: napA
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase molybdopterin-binding subunit NapA; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: SO_0849
symbol: napD
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase chaperone NapD; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: SO_0859
symbol: SO_0859
gene_biotype: protein_coding
description:
  Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.


ensembl_gene_id: SO_0861
symbol: ygfZ
gene_biotype: protein_coding
description:
  Folate-dependent protein involved in synthesis and repair of FeS clusters YgfZ; Belongs to the GcvT family.


ensembl_gene_id: SO_0862
symbol: serA
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SO_0869
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: SO_0870
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: SO_0872
symbol: pcnB
gene_biotype: protein_coding
description:
  polyA polymerase PcnB; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: SO_0873
symbol: yadB
gene_biotype: protein_coding
description:
  glutamyl-Q-tRNA-Asp synthetase YadB; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: SO_0874
symbol: dksA
gene_biotype: protein_coding
description:
  RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: SO_0902
symbol: nqrA
gene_biotype: protein_coding
description:
  Na-translocating NADH-quinone reductase subunit A NqrA; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: SO_0903
symbol: nqrB
gene_biotype: protein_coding
description:
  Na-translocating NADH-quinone reductase subunit B NqrB; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: SO_0904
symbol: nqrC
gene_biotype: protein_coding
description:
  Na-translocating NADH-quinone reductase subunit C NqrC; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: SO_0905
symbol: nqrD
gene_biotype: protein_coding
description:
  Na-translocating NADH-quinone reductase subunit D NqrD; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: SO_0906
symbol: nqrE
gene_biotype: protein_coding
description:
  Na-translocating NADH-quinone reductase subunit E NqrE; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: SO_0907
symbol: nqrF
gene_biotype: protein_coding
description:
  Na-translocating NADH-quinone reductase subunit F NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: SO_0917
symbol: yjjX
gene_biotype: protein_coding
description:
  Inosine/xanthosine triphosphatase YjjX; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: SO_0922
symbol: SO_0922
gene_biotype: protein_coding
description:
  Dicarboxylate:amino acid:cation symporter DAACS family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SO_0929
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase MetK; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: SO_0931
symbol: e4pd
gene_biotype: protein_coding
description:
  D-erythrose-4-phosphate dehydrogenase E4pd; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: SO_0933
symbol: fba
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase class II Calvin cycle subtype Fba; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: SO_0945
symbol: SO_0945
gene_biotype: protein_coding
description:
  RND superfamily efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_0946
symbol: SO_0946
gene_biotype: protein_coding
description:
  RND superfamily efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_0947
symbol: srmB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: SO_0948
symbol: yfiC
gene_biotype: protein_coding
description:
  tRNA (adenine-N(6)-)-methyltransferase YfiC; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: SO_0949
symbol: brnQ
gene_biotype: protein_coding
description:
  Branched-chain amino acid: cation symporter BrnQ; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: SO_0950
symbol: xerD
gene_biotype: protein_coding
description:
  Integrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: SO_0951
symbol: dsbC
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: SO_0958
symbol: ahpC
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase peroxiredoxin component AhpC; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: SO_0959
symbol: pepA1
gene_biotype: protein_coding
description:
  Periplasmic leucyl metal-dependent aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).


ensembl_gene_id: SO_0968
symbol: ldhA
gene_biotype: protein_coding
description:
  Fermentative lactate dehydrogenase NADH dependent LdhA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SO_0970
symbol: fccA
gene_biotype: protein_coding
description:
  Periplasmic fumarate reductase FccA; Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO). This enzyme is essentially unidirectional (By similarity); In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: SO_0980
symbol: rumB
gene_biotype: protein_coding
description:
  23S rRNA (uracil747-C5)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.


ensembl_gene_id: SO_0988
symbol: SO_0988
gene_biotype: protein_coding
description:
  Molybdopterin-binding oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SO_0991
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2 PrfB; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: SO_1009
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit N NuoN; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: SO_1012
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit K NuoK; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: SO_1013
symbol: nuoJ
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit J NuoJ; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SO_1014
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit I NuoI; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SO_1015
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit H NuoH; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: SO_1016
symbol: nuoG
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit G NuoG; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).


ensembl_gene_id: SO_1017
symbol: nuoF
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit F NuoF; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: SO_1019
symbol: nuoCD
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit CD NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: SO_1020
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit B NuoB; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: SO_1021
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase subunit A NuoA; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: SO_1030
symbol: metH
gene_biotype: protein_coding
description:
  B12-dependent 5-methyltetrahydrofolate--homocysteine methyltransferase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: SO_1034
symbol: btuC
gene_biotype: protein_coding
description:
  ABC-type cobalamin uptake system permease component BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SO_1035
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: SO_1036
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin 5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: SO_1037
symbol: cobU
gene_biotype: protein_coding
description:
  Bifunctional cobinamide kinase/cobinamide phosphate guanylyltransferase CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: SO_1038
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: SO_1039
symbol: cobO
gene_biotype: protein_coding
description:
  cob(I)alamin adenosyltransferase CobO; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: SO_1044
symbol: artI
gene_biotype: protein_coding
description:
  ABC-type arginine uptakesystem substrate-binding component ArtI; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: SO_1051
symbol: opgD
gene_biotype: protein_coding
description:
  Periplasmic glucan biosynthesis protein OpgD; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: SO_1072
symbol: gbpA
gene_biotype: protein_coding
description:
  N-acetylglucosamine-binding protein A GbpA; Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin. Belongs to the GbpA family.


ensembl_gene_id: SO_1075
symbol: SO_1075
gene_biotype: protein_coding
description:
  Dipeptydil peptidase S46 family; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.


ensembl_gene_id: SO_1090
symbol: SO_1090
gene_biotype: protein_coding
description:
  Cytoplasmic ApbE family protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: SO_1097
symbol: rlmG
gene_biotype: protein_coding
description:
  23S rRNA (guanine1835-N2)-methyltransferase RlmG; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: SO_1100
symbol: SO_1100
gene_biotype: protein_coding
description:
  TRAP transporter substrate-binding component; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.


ensembl_gene_id: SO_1101
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: SO_1109
symbol: apbE
gene_biotype: protein_coding
description:
  Fe-S assembly/repair lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: SO_1111
symbol: brf2
gene_biotype: protein_coding
description:
  Bacterioferritin subunit 2 Bfr2; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: SO_1112
symbol: brf1
gene_biotype: protein_coding
description:
  Bacterioferritin subunit 1 Bfr1; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: SO_1114
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV DinB; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: SO_1121
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: SO_1122
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: SO_1127
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: SO_1140
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.


ensembl_gene_id: SO_1149
symbol: rlmI
gene_biotype: protein_coding
description:
  23S rRNA (cytosine1962-C5)-methyltransferase RlmI; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.


ensembl_gene_id: SO_1150
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose 5-phosphate isomerase RpiA; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: SO_1161
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoic acid synthetase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: SO_1162
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyl(octanoyl) transferase LipB; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: SO_1165
symbol: rlpA
gene_biotype: protein_coding
description:
  Septal ring lipoprotein RlpA; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: SO_1167
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: SO_1168
symbol: mrdA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2 MrdA; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: SO_1169
symbol: rlmH
gene_biotype: protein_coding
description:
  23S rRNA (pseudouridine1915-N3)-methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: SO_1170
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: SO_1171
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: SO_1173
symbol: lptE
gene_biotype: protein_coding
description:
  OM lipoprotein component of lipopolysaccharide assembly complex chaperone LptE; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: SO_1177
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase Lnt; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: SO_1179
symbol: ybeY
gene_biotype: protein_coding
description:
  rRNA maturation factor YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: SO_1181
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: SO_1184
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase Pth; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: SO_1185
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding and nucleic acid-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: SO_1191
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: SO_1193
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: SO_1194
symbol: secF
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: SO_1196
symbol: rrmJ
gene_biotype: protein_coding
description:
  23S rRNA (uridine2552-2'-O)-methyltransferase RrmJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: SO_1197
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent zinc metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: SO_1198
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: SO_1199
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase GlmM; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: SO_1200
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomeraseTpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: SO_1201
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: SO_1202
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation factor RimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: SO_1203
symbol: nusA
gene_biotype: protein_coding
description:
  N utilization substance protein A NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: SO_1204
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2 InfB; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: SO_1205
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A RbfA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: SO_1206
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine55 synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: SO_1207
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15 RpsO; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.


ensembl_gene_id: SO_1209
symbol: pnpA
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase PnpA; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: SO_1211
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3 PrfC; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: SO_1214
symbol: SO_1214
gene_biotype: protein_coding
description:
  Na+ dependent nucleoside transporter NupC family; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: SO_1217
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: SO_1218
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase DeoA; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: SO_1219
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase DeoB; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: SO_1226
symbol: radA
gene_biotype: protein_coding
description:
  ATP-dependent protease RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: SO_1227
symbol: SO_1227
gene_biotype: protein_coding
description:
  c-di-GMP-binding protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: SO_1230
symbol: torS
gene_biotype: protein_coding
description:
  Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS.


ensembl_gene_id: SO_1231
symbol: torD
gene_biotype: protein_coding
description:
  TorA-specific chaperone TorD; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily.


ensembl_gene_id: SO_1232
symbol: torA
gene_biotype: protein_coding
description:
  trimethylamine-N-oxide reductase TorA; Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.


ensembl_gene_id: SO_1233
symbol: torC
gene_biotype: protein_coding
description:
  Trimethylamine N-oxide reductase membrane anchored cytochrome c component TorC; Belongs to the TorC/TorY family.


ensembl_gene_id: SO_1258
symbol: purA-2
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: SO_1270
symbol: potF
gene_biotype: protein_coding
description:
  ABC-type putrescine uptake system substrate-binding component PotF; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: SO_1271
symbol: potG
gene_biotype: protein_coding
description:
  ABC-type putrescine uptake system ATPase component PotG; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SO_1275
symbol: puuC
gene_biotype: protein_coding
description:
  Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SO_1276
symbol: puuE
gene_biotype: protein_coding
description:
  GABA aminotransferase PLP-dependent PuuE; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SO_1284
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma-70 factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: SO_1286
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: SO_1289
symbol: ygiD
gene_biotype: protein_coding
description:
  Essential endopeptidase YgiD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: SO_1290
symbol: plyY
gene_biotype: protein_coding
description:
  acyl-PO4 glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: SO_1291
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: SO_1293
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenol diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: SO_1296
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase Cca; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: SO_1301
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: SO_1304
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: SO_1307
symbol: aqpZ
gene_biotype: protein_coding
description:
  Aquaporin Z AqpZ; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: SO_1313
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: SO_1315
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase TyrS; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: SO_1322
symbol: mtnN
gene_biotype: protein_coding
description:
  5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase MtnN; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: SO_1328
symbol: oxyR
gene_biotype: protein_coding
description:
  Transcriptional regulator of oxidative stress OxyR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_1330
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family.


ensembl_gene_id: SO_1331
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase RppH; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: SO_1334
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase Lgt; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: SO_1335
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: SO_1336
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: SO_1338
symbol: nhaR
gene_biotype: protein_coding
description:
  Transcriptional activator of osmotic stress protection NhaR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_1339
symbol: sdhE
gene_biotype: protein_coding
description:
  Protein of unknown function DUF339; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.


ensembl_gene_id: SO_1341
symbol: nadB
gene_biotype: protein_coding
description:
  L-aspartate oxidase component of quinolinate synthetase NadB; Catalyzes the oxidation of L-aspartate to iminoaspartate.


ensembl_gene_id: SO_1343
symbol: rseA
gene_biotype: protein_coding
description:
  sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]


ensembl_gene_id: SO_1346
symbol: lepA
gene_biotype: protein_coding
description:
  Elongation factor 4 LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: SO_1348
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III Rnc; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: SO_1349
symbol: era
gene_biotype: protein_coding
description:
  30S ribosome assembly GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: SO_1351
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate synthase PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: SO_1352
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-(acyl-carrier protein) synthase AcpS; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: SO_1356
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...]


ensembl_gene_id: SO_1358
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: SO_1359
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N1)-methyltransferase TrmD; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: SO_1360
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19 RplS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: SO_1361
symbol: aroF
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase tyr-sensitive AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: SO_1368
symbol: pepA
gene_biotype: protein_coding
description:
  Cytoplasmic leucine metal-dependent aminopeptidase PepA; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).


ensembl_gene_id: SO_1375
symbol: SO_1375
gene_biotype: protein_coding
description:
  Thermostable carboxypeptidase 1; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: SO_1414
symbol: SO_1414
gene_biotype: protein_coding
description:
  Flavocytochrome c flavin subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: SO_1418
symbol: SO_1418
gene_biotype: protein_coding
description:
  ApbE family protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: SO_1421
symbol: ifcA
gene_biotype: protein_coding
description:
  Periplasmic tetraheme flavocytochrome IfcA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: SO_1422
symbol: ifcR
gene_biotype: protein_coding
description:
  Fe(III)-induced transcriptional regulator IfcR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_1429
symbol: dmsA
gene_biotype: protein_coding
description:
  Extracellular dimethyl sulfoxide/manganese oxide reductase molybdopterin-binding subunit DmsA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SO_1473
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein SmpB; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...]


ensembl_gene_id: SO_1476
symbol: bamE
gene_biotype: protein_coding
description:
  Beta barrel protein translocation component BamE; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: SO_1481
symbol: kefC
gene_biotype: protein_coding
description:
  Glutathione-gated K(+)-efflux system KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: SO_1492
symbol: SO_1492
gene_biotype: protein_coding
description:
  Surface bound cyclophilin-type A-like peptidylprolyl cis-trans isomerase lipoprotein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: SO_1494
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme GlgB; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: SO_1496
symbol: glgP
gene_biotype: protein_coding
description:
  Glycogen phosphorylase GlgP; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: SO_1498
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase GlgC; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: SO_1523
symbol: nadF
gene_biotype: protein_coding
description:
  NAD kinase NadF; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: SO_1524
symbol: grpE
gene_biotype: protein_coding
description:
  Heat shock nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sev [...]


ensembl_gene_id: SO_1525
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: SO_1526
symbol: ispA
gene_biotype: protein_coding
description:
  Geranyl-diphosphate synthase/farnesyl-diphosphate synthase IspA; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: SO_1527
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit XseB; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: SO_1531
symbol: thiI
gene_biotype: protein_coding
description:
  Thiazole biosynthesis/tRNA modification proteinThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: SO_1533
symbol: gcvA
gene_biotype: protein_coding
description:
  Transcriptional activator of glycine metabolism GcvA; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_1536
symbol: rlmM
gene_biotype: protein_coding
description:
  23S rRNA (cytidine2498-2'-O)-methyltransferase RlmM; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: SO_1549
symbol: xni
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease III associated protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: SO_1559
symbol: phoR
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Phosphate-responsive two component signal transduction system histidine kinase with PAS and DUF3329 domains PhoR.


ensembl_gene_id: SO_1575
symbol: rsmB-2
gene_biotype: protein_coding
description:
  tRNA/rRNA cytosine-C5-methylase RsmB; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: SO_1599
symbol: pfaC
gene_biotype: protein_coding
description:
  Multi-domain beta-ketoacyl synthase PfaC; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SO_1608
symbol: queF
gene_biotype: protein_coding
description:
  NADPH-dependent preQ0 reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: SO_1609
symbol: syd
gene_biotype: protein_coding
description:
  SecY binding protein Syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: SO_1624
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: SO_1625
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase DapD; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: SO_1626
symbol: glnD
gene_biotype: protein_coding
description:
  protein-P-II uridylyltransferase GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: SO_1627
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase Map; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: SO_1630
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor EF-Ts Tsf; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: SO_1632
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor Frr; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: SO_1633
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase UppS; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: SO_1635
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: SO_1637
symbol: bamA
gene_biotype: protein_coding
description:
  Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: SO_1639
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-(3-hydroxymyristoyl) glucosamine n-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: SO_1640
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: SO_1641
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: SO_1642
symbol: lpxB
gene_biotype: protein_coding
description:
  Lipid A disaccharide synthase LpxB; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: SO_1643
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease HII RnhB; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: SO_1645
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: SO_1647
symbol: kefB
gene_biotype: protein_coding
description:
  Glutathione-gated K(+)-efflux system KefB; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: SO_1653
symbol: SO_1653
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase family; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: SO_1663
symbol: napF
gene_biotype: protein_coding
description:
  Nitrate reductase (NapA) maturase NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: SO_1676
symbol: metA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase MetA; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: SO_1691
symbol: blc
gene_biotype: protein_coding
description:
  Lipocalin family lipoprotein Blc; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: SO_1725
symbol: pstB
gene_biotype: protein_coding
description:
  ABC-type high affinity phosphate uptake system ATPase component PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: SO_1726
symbol: phoU
gene_biotype: protein_coding
description:
  Transcriptional regulator of high affinity phosphate uptake system PhoU; Plays a role in the regulation of phosphate uptake.


ensembl_gene_id: SO_1742
symbol: oleA
gene_biotype: protein_coding
description:
  Polyolefin biosynthetic pathway thiolase OleA; Involved in olefin biosynthesis. Catalyzes a non-decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28- hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.


ensembl_gene_id: SO_1743
symbol: oleB
gene_biotype: protein_coding
description:
  Polyolefin biosynthetic pathway thioesterase OleB; Involved in olefin biosynthesis. Catalyzes the elimination of carbon dioxide from beta-lactones to form the final olefin product (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.


ensembl_gene_id: SO_1744
symbol: oleC
gene_biotype: protein_coding
description:
  Polyolefin biosynthetic pathway AMP transfer protein OleC; Involved in olefin biosynthesis. Catalyzes the conversion of 2-alkyl-3-hydroxyalkanoic acids to beta-lactones in the presence of ATP (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28-hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.


ensembl_gene_id: SO_1745
symbol: oleD
gene_biotype: protein_coding
description:
  Polyolefin biosynthetic pathway dehydrogenase/isomerase OleD; Involved in olefin biosynthesis. Catalyzes the reversible stereospecific NADPH-dependent reduction of 2-alkyl-3- oxoalkanoic acids to 2-alkyl-3-hydroxyalkanoic acids (By similarity). The S.oneidensis oleABCD genes produce 3,6,9,12,15,19,22,25,28- hentriacontanonaene, which may aid the cells in adapting to a sudden drop in temperature.


ensembl_gene_id: SO_1784
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: SO_1789
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-23-diacylglucosamine hydrolase LpxH; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: SO_1790
symbol: ppiB
gene_biotype: protein_coding
description:
  Cytoplasmic peptidyl-prolyl cis-trans isomerase PpiB; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: SO_1792
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: SO_1793
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor peptidyl-prolyl cis-trans isomerase Tig; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: SO_1794
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: SO_1795
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: SO_1796
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La Lon; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: SO_1797
symbol: hupB
gene_biotype: protein_coding
description:
  Histone-like DNA-binding protein HupB; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: SO_1800
symbol: fabV
gene_biotype: protein_coding
description:
  Enoyl acyl-carrier-protein reductase FabV; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: SO_1828
symbol: tonB2
gene_biotype: protein_coding
description:
  TonB2 mediated energy transduction system energy transducer component TonB2; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: SO_1851
symbol: rlmL
gene_biotype: protein_coding
description:
  23S rRNA (guanine2445-N2)-methyltransferase RlmL; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: SO_1855
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor Rmf; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: SO_1856
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: SO_1861
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC C subunit UvrC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: SO_1862
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SO_1870
symbol: speA
gene_biotype: protein_coding
description:
  Biosynthetic arginine decarboxylase SpeA; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.


ensembl_gene_id: SO_1879
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: SO_1880
symbol: bamD
gene_biotype: protein_coding
description:
  Beta barrel protein translocation component BamD; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: SO_1881
symbol: SO_1881
gene_biotype: protein_coding
description:
  HAE1 family efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_1882
symbol: SO_1882
gene_biotype: protein_coding
description:
  HAE1 family efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_1902
symbol: gnd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase decarboxylating Gnd; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: SO_1910
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: SO_1916
symbol: SO_1916
gene_biotype: protein_coding
description:
  DMSO-responsive transcriptional activator of efflux pump LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_1923
symbol: SO_1923
gene_biotype: protein_coding
description:
  RND superfamily efflux pump permease component 1; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_1924
symbol: SO_1924
gene_biotype: protein_coding
description:
  RND superfamily efflux pump permease component 2; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_1928
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase flavoprotein subunit SdhA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: SO_1929
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase iron-sulfur protein SdhB; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: SO_1931
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: SO_1932
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthase beta subunit SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: SO_1933
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthase alpha subunit SucD; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: SO_1938
symbol: cobB
gene_biotype: protein_coding
description:
  Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.


ensembl_gene_id: SO_1941
symbol: corA
gene_biotype: protein_coding
description:
  Divalent cation (Mg2+, Co2+, Ni2+) transporter CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: SO_1948
symbol: gltP
gene_biotype: protein_coding
description:
  Glutamate/aspartate:proton symporter GltP; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SO_1965
symbol: hmgR
gene_biotype: protein_coding
description:
  Homogentisate-responsive transcriptional repressor of homogenetisate degradation HmgR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_2006
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C DusC; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: SO_2012
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: SO_2014
symbol: ybaB
gene_biotype: protein_coding
description:
  DNA-binding protein YbaB; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: SO_2015
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: SO_2018
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: SO_2019
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase HemH; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: SO_2021
symbol: nadE
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: SO_2042
symbol: yedY
gene_biotype: protein_coding
description:
  Oxidoreductase molybdenum-binding subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able t [...]


ensembl_gene_id: SO_2043
symbol: yedZ
gene_biotype: protein_coding
description:
  Oxidoreductase cytochrome b subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic sub [...]


ensembl_gene_id: SO_2044
symbol: gloA
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase GloA; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: SO_2054
symbol: frmA
gene_biotype: protein_coding
description:
  S-(hydroxymethyl)glutathione dehydrogenase FrmA; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: SO_2055
symbol: frmB
gene_biotype: protein_coding
description:
  S-formylglutathione hydrolase FrmB; Serine hydrolase involved in the detoxification of formaldehyde.


ensembl_gene_id: SO_2067
symbol: hisIE
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase HisIE; In the C-terminal section; belongs to the PRA-PH family.


ensembl_gene_id: SO_2068
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase cyclase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: SO_2069
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HisA.


ensembl_gene_id: SO_2070
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase glutamine amidotransferase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: SO_2071
symbol: hisB
gene_biotype: protein_coding
description:
  Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.


ensembl_gene_id: SO_2072
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase HisC; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: SO_2073
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: SO_2074
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase HisG; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: SO_2085
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase alpha subunit PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: SO_2086
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase beta subunit PheT; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: SO_2087
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor alpha subunit IhfA; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: SO_2088
symbol: lpxM
gene_biotype: protein_coding
description:
  KDO 2-(lauroyl)-lipid IVA acyltransferase LpxM; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: SO_2089
symbol: hypA
gene_biotype: protein_coding
description:
  NiFe hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: SO_2094
symbol: hypF
gene_biotype: protein_coding
description:
  NiFe hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: SO_2098
symbol: hyaB
gene_biotype: protein_coding
description:
  Periplasmic [Ni-Fe] hydrogenase large subunit HyaB; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: SO_2107
symbol: opgG
gene_biotype: protein_coding
description:
  Periplasmic glucan biosynthesis protein OpgG; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: SO_2108
symbol: opgH
gene_biotype: protein_coding
description:
  Glucan biosynthesis glucosyltransferase family 2 OpgH; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: SO_2112
symbol: rplY
gene_biotype: protein_coding
description:
  50S ribosomal protein L25 RplY; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: SO_2124
symbol: cheR
gene_biotype: protein_coding
description:
  Chemotaxis signal transduction system MCP methyltransferase CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: SO_2125
symbol: cheD
gene_biotype: protein_coding
description:
  Chemotaxis signal transduction system chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: SO_2126
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis signal transduction system response regulator with glutamate methylesterase domain CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: SO_2136
symbol: adhE
gene_biotype: protein_coding
description:
  Aldehyde-alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: SO_2147
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V alpha subunit RecD; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination a [...]


ensembl_gene_id: SO_2148
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V beta subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination an [...]


ensembl_gene_id: SO_2149
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V gamma subunit RecC; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination a [...]


ensembl_gene_id: SO_2203
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase DgkA; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: SO_2215
symbol: SO_2215
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase RsmB family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: SO_2216
symbol: SO_2216
gene_biotype: protein_coding
description:
  Bifunctional diguanylate cyclase with GAF and PAS sensory domains/signalling protein with EAL domain.


ensembl_gene_id: SO_2222
symbol: fumB
gene_biotype: protein_coding
description:
  Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: SO_2237
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) phosphoenolpyruvate-protein phosphotransferase PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: SO_2250
symbol: nagZ
gene_biotype: protein_coding
description:
  beta-N-acetylglucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: SO_2255
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor Mfd; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: SO_2258
symbol: lolD
gene_biotype: protein_coding
description:
  ABC-type lipoprotein release system ATPase component LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: SO_2261
symbol: trmJ
gene_biotype: protein_coding
description:
  tRNA (cytidine32/uridine32-2'-O)-methyltransferase TrmJ; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: SO_2263
symbol: iscR
gene_biotype: protein_coding
description:
  Transcriptional repressor of iron-sulfur cluster assembly genes IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: SO_2264
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: SO_2265
symbol: iscU
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: SO_2266
symbol: iscA
gene_biotype: protein_coding
description:
  FeS cluster assembly acessory protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: SO_2267
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone Hsc20 HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: SO_2268
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: SO_2274
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: SO_2295
symbol: norM
gene_biotype: protein_coding
description:
  drug:Na+ antiporter NorM; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.


ensembl_gene_id: SO_2299
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase ThrS; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).


ensembl_gene_id: SO_2300
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor IF-3 InfC; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: SO_2302
symbol: rplT
gene_biotype: protein_coding
description:
  50S ribosomal protein L20 RplT; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: SO_2306
symbol: ftsK
gene_biotype: protein_coding
description:
  Double-stranded DNA translocase FtsK; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the directi [...]


ensembl_gene_id: SO_2307
symbol: lolA
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: SO_2309
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: SO_2310
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase SerS; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: SO_2328
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P Efp; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: SO_2330
symbol: fldA
gene_biotype: protein_coding
description:
  Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: SO_2335
symbol: seqA
gene_biotype: protein_coding
description:
  Negative regulator of DNA replication SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: SO_2337
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: SO_2338
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase AstE; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: SO_2342
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: SO_2347
symbol: gapB
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase GapB; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: SO_2351
symbol: SO_2351
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0052; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: SO_2354
symbol: ydaO
gene_biotype: protein_coding
description:
  tRNA(Cytosine32)-2-thiocytidine synthetaseYdaO; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: SO_2356
symbol: fnr
gene_biotype: protein_coding
description:
  Oxygen-responsive transcriptional regulator of anaerobiosis response Fnr; Regulates anaerobic growth on fumarate, nitrite, Fe(3+), TMAO, DMSO, thiosulfate and sulfite, but not on nitrate nor Mn(4+).


ensembl_gene_id: SO_2361
symbol: ccoP
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome c oxidase subunit III CcoP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: SO_2364
symbol: ccoN
gene_biotype: protein_coding
description:
  Cbb3-type cytochrome c oxidase subunit I CcoN; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: SO_2398
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: SO_2399
symbol: yciM
gene_biotype: protein_coding
description:
  Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: SO_2400
symbol: lapA
gene_biotype: protein_coding
description:
  Membrane protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: SO_2401
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor beta subunit IhfB; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: SO_2402
symbol: rpsA
gene_biotype: protein_coding
description:
  Ribosomal protein S1 RpsA; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: SO_2404
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: SO_2410
symbol: serC
gene_biotype: protein_coding
description:
  Bifunctional 3-phosphoserine aminotransferase/phosphohydroxythreonine SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: SO_2411
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: SO_2413
symbol: ubiG
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: SO_2415
symbol: nrdA
gene_biotype: protein_coding
description:
  Aerobic ribonucleoside-diphosphate reductase alpha subunit NrdA; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: SO_2429
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: SO_2430
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: SO_2431
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: SO_2433
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase AspS; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: SO_2435
symbol: cmoA
gene_biotype: protein_coding
description:
  tRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase CmoA; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: SO_2436
symbol: cmoB
gene_biotype: protein_coding
description:
  tRNA (5-methoxyuridine) 34 synthase CmoD; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: SO_2441
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole-phosphate synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: SO_2444
symbol: thiDE
gene_biotype: protein_coding
description:
  Bifunctional hydroxy-(phospho)methylpyrimidine kinase/thiamine-phosphate pyrophosphorylase ThiDE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: SO_2445
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamin biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: SO_2471
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase DapE; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: SO_2474
symbol: can
gene_biotype: protein_coding
description:
  Beta-class carbonic anhydrase Can; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: SO_2476
symbol: kdnA
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate); Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: SO_2477
symbol: kdnB
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase iron-containing; Catalyzes the first step of the biosynthesis of Kdo8N (8- amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate).


ensembl_gene_id: SO_2478
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase KdsB; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family.


ensembl_gene_id: SO_2484
symbol: yfbR
gene_biotype: protein_coding
description:
  5' nucleotidase YfbR; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: SO_2485
symbol: dgt
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase Dgt; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: SO_2487
symbol: edd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydratase Edd; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: SO_2489
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase Zwf; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: SO_2490
symbol: hexR
gene_biotype: protein_coding
description:
  RpiR family transcriptional regulator, carbohydrate utilization regulator; 2-keto-3-deoxy-6-phosphogluconate-responsive transcriptional regulator of central carbohydrate metabolism HexR.


ensembl_gene_id: SO_2501
symbol: queE
gene_biotype: protein_coding
description:
  Queuosine biosynthesis radical activating enzyme QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: SO_2503
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: SO_2506
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC B subunit UvrB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissoc [...]


ensembl_gene_id: SO_2508
symbol: rnfA
gene_biotype: protein_coding
description:
  Ion (H+ or Na+)-translocating NADH:ferredoxin oxidoreductase subunit RnfA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: SO_2509
symbol: rnfB
gene_biotype: protein_coding
description:
  Ion (H+ or Na+)-translocating NADH:ferredoxin oxidoreductase subunit RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: SO_2510
symbol: rnfC
gene_biotype: protein_coding
description:
  Ion (H+ or Na+)-translocating NADH:ferredoxin oxidoreductase subunit RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: SO_2511
symbol: rnfD
gene_biotype: protein_coding
description:
  Ion (H+ or Na+)-translocating NADH:ferredoxin oxidoreductase subunit RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: SO_2512
symbol: rnfG
gene_biotype: protein_coding
description:
  Ion (H+ or Na+)-translocating NADH:ferredoxin oxidoreductase subunit RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: SO_2513
symbol: rnfE
gene_biotype: protein_coding
description:
  Ion (H+ or Na+)-translocating NADH:ferredoxin oxidoreductase subunit RnfE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: SO_2514
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III Nth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: SO_2537
symbol: SO_2537
gene_biotype: protein_coding
description:
  Sodium:proton antiporter CPA1 family; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: SO_2539
symbol: SO_2539
gene_biotype: protein_coding
description:
  Two component signal transduction system response regulator with cyclic diguanylate phosphodiesterase activity and PAS sensory domain.


ensembl_gene_id: SO_2544
symbol: SO_2544
gene_biotype: protein_coding
description:
  Two component signal transduction system hybrid histidine kinase/response regulator with Hpt domain.


ensembl_gene_id: SO_2559
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III epsilon subunit DnaQ; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: SO_2563
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase GloB; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: SO_2567
symbol: SO_2567
gene_biotype: protein_coding
description:
  Rra-like regulator of RNAse E; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).


ensembl_gene_id: SO_2576
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: SO_2578
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: SO_2580
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D Rnd; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: SO_2588
symbol: selR
gene_biotype: protein_coding
description:
  methionine-R-sulfoxide reductase SelR; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: SO_2590
symbol: rbgA
gene_biotype: protein_coding
description:
  50s ribosomal subunit maturation GTPase RbgA; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: SO_2591
symbol: zapC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1379; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: SO_2592
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: SO_2602
symbol: proQ
gene_biotype: protein_coding
description:
  Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.


ensembl_gene_id: SO_2609
symbol: rsmF
gene_biotype: protein_coding
description:
  16S rRNA (cytosine1407-C5)-methyltransferase RsmF; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.


ensembl_gene_id: SO_2613
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: SO_2614
symbol: yceG
gene_biotype: protein_coding
description:
  Protein YceG; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: SO_2618
symbol: apbC
gene_biotype: protein_coding
description:
  Scaffold protein for [4Fe-4S] cluster assembly ApbC; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: SO_2619
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase MetG; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: SO_2623
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase Aat; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: SO_2624
symbol: bpt
gene_biotype: protein_coding
description:
  leucyl-tRNA-protein transferase Bpt; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: SO_2625
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1 InfA; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: SO_2627
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: SO_2633
symbol: trmU
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TrmU; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: SO_2644
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: SO_2645
symbol: ydiA
gene_biotype: protein_coding
description:
  Putative phosphotransferase YdiA; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: SO_2646
symbol: aroH
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase trp-sensitive AroH; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: SO_2648
symbol: SO_2648
gene_biotype: protein_coding
description:
  Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family.


ensembl_gene_id: SO_2649
symbol: cysB
gene_biotype: protein_coding
description:
  Transcriptional activator of cys regulon CysB; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_2705
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...]


ensembl_gene_id: SO_2706
symbol: astB
gene_biotype: protein_coding
description:
  N-succinylarginine dihydrolase AstB; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: SO_2730
symbol: pepE
gene_biotype: protein_coding
description:
  Dipeptidase E PepE; Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.


ensembl_gene_id: SO_2731
symbol: mdoG
gene_biotype: protein_coding
description:
  Periplasmic glucan biosynthesis protein MdoG; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).


ensembl_gene_id: SO_2737
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: SO_2738
symbol: bioC
gene_biotype: protein_coding
description:
  SAM-dependent methylase involved in biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: SO_2740
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: SO_2741
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SO_2742
symbol: prlS
gene_biotype: protein_coding
description:
  Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS.


ensembl_gene_id: SO_2743
symbol: acs
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: SO_2746
symbol: ybgF
gene_biotype: protein_coding
description:
  TolA energy-transducing system periplasmic component YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: SO_2747
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: SO_2748
symbol: tolB
gene_biotype: protein_coding
description:
  TonB biopolymer transport system periplasmic component TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: SO_2750
symbol: tolR
gene_biotype: protein_coding
description:
  TolA energy-transducing system inner membrane component TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: SO_2751
symbol: tolQ
gene_biotype: protein_coding
description:
  TolA energy-transducing system inner membrane component TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: SO_2755
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: SO_2759
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: SO_2761
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: SO_2774
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase II FabF; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: SO_2775
symbol: acpP
gene_biotype: protein_coding
description:
  Acyl carrier protein AcpP; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: SO_2776
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SO_2778
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase III FabH; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SO_2779
symbol: plsX
gene_biotype: protein_coding
description:
  phosphate:acyl-ACP acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: SO_2782
symbol: yceF
gene_biotype: protein_coding
description:
  Maf septum formation family protein YceF; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: SO_2784
symbol: rluC
gene_biotype: protein_coding
description:
  23S rRNA pseudouridine955/2504/2580 synthase RluC; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: SO_2785
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease E Rne; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: SO_2791
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase Cdd; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: SO_2801
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase LpxK; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: SO_2802
symbol: msbA
gene_biotype: protein_coding
description:
  ABC-type lipid A export system bifunctional ATPase and permease components MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: SO_2831
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II RibA; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: SO_2833
symbol: nrdG
gene_biotype: protein_coding
description:
  Anaerobic ribonucleoside-triphosphate reductase activating protein NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: SO_2844
symbol: sbcD
gene_biotype: protein_coding
description:
  dsDNA exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: SO_2853
symbol: fabH-2
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: SO_2857
symbol: SO_2857
gene_biotype: protein_coding
description:
  Putative solute:sodium symporter large subunit; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: SO_2866
symbol: argP
gene_biotype: protein_coding
description:
  Arginine/lysine-responsive transcriptional regulator ArgP; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_2869
symbol: yfgC
gene_biotype: protein_coding
description:
  Periplasmic Zn-dependent protease YfgC; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: SO_2881
symbol: sodB
gene_biotype: protein_coding
description:
  Fe/Mn superoxide dismutase SodB; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: SO_2885
symbol: fadR
gene_biotype: protein_coding
description:
  Transcriptional regulator of fatty acid metabolism FadR; Multifunctional regulator of fatty acid metabolism.


ensembl_gene_id: SO_2886
symbol: nhaB
gene_biotype: protein_coding
description:
  Sodium:proton antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: SO_2887
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: SO_2895
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine-phosphate oxidase PdxH; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: SO_2896
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase NAD-dependent LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: SO_2897
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: SO_2898
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome partition protein Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: SO_2899
symbol: cysZ
gene_biotype: protein_coding
description:
  Putative sulfate transporter CysZ; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: SO_2913
symbol: pflA
gene_biotype: protein_coding
description:
  Pyruvate formate-lyase 1 activating enzyme PflA; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: SO_2915
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: SO_2916
symbol: pta
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: SO_2923
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium:glutamate symporter GltS; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: SO_2993
symbol: SO_2993
gene_biotype: protein_coding
description:
  Lambda phage type II DNA modification methyltransferase; Belongs to the methyltransferase superfamily.


ensembl_gene_id: SO_3014
symbol: scpB
gene_biotype: protein_coding
description:
  Segregation and condensation protein ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SO_3015
symbol: scpA
gene_biotype: protein_coding
description:
  Segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: SO_3021
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: SO_3022
symbol: trpCF
gene_biotype: protein_coding
description:
  Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family.


ensembl_gene_id: SO_3023
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta subunit TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: SO_3024
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: SO_3035
symbol: ispZ
gene_biotype: protein_coding
description:
  Intracellular septation protein IspZ; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: SO_3048
symbol: SO_3048
gene_biotype: protein_coding
description:
  Isoquinoline 1-oxidoreductase subunit beta; Aldehyde oxidase / xanthine dehydrogenase family molybdopterin cytosine dinucleotide-binding subunit.


ensembl_gene_id: SO_3061
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase III TopB; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...]


ensembl_gene_id: SO_3064
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: SO_3067
symbol: folC
gene_biotype: protein_coding
description:
  Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: SO_3068
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: SO_3070
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate semialdehyde dehydrogenese Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: SO_3071
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase PdxB; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: SO_3072
symbol: fabB
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase I FabB; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SO_3073
symbol: mnmC
gene_biotype: protein_coding
description:
  Bifunctional 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.


ensembl_gene_id: SO_3079
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase AroC; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: SO_3080
symbol: prmB
gene_biotype: protein_coding
description:
  50S subunit L3 protein glutamine methyltransferase PrmB; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: SO_3088
symbol: fadJ
gene_biotype: protein_coding
description:
  Anaerobic fatty oxidation complex alpha subunit FadJ; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: SO_3089
symbol: fadI
gene_biotype: protein_coding
description:
  Anaerobic fatty oxidation complex beta subunit FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: SO_3102
symbol: SO_3102
gene_biotype: protein_coding
description:
  Thiophosphate efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_3103
symbol: SO_3103
gene_biotype: protein_coding
description:
  Thiophosphate efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_3112
symbol: yajC
gene_biotype: protein_coding
description:
  SecDF preprotein translocase-associated protein YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: SO_3113
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to for [...]


ensembl_gene_id: SO_3114
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: SO_3120
symbol: agaO
gene_biotype: protein_coding
description:
  Sugar oxidoreductase AgaO; Glycosidase that has specific alpha-N-acetylgalactosaminidase activity; Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.


ensembl_gene_id: SO_3122
symbol: sstT
gene_biotype: protein_coding
description:
  serine/threonine:Na+ symporter SstT; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SO_3126
symbol: ogt
gene_biotype: protein_coding
description:
  Constitutive O6-methylguanine-DNA methyltransferase II Ogt; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: SO_3127
symbol: SO_3127
gene_biotype: protein_coding
description:
  Multifunctional transcriptional regulator of DNA repair AraC family/ DNA glycosylase / 8-oxoguanine DNA glycosylase.


ensembl_gene_id: SO_3130
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase GltX; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: SO_3138
symbol: dctD
gene_biotype: protein_coding
description:
  Two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD; C4-dicarboxylate-responsive two component Sigma54-dependent signal transduction system response regulator DctD.


ensembl_gene_id: SO_3154
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase ProS; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involve [...]


ensembl_gene_id: SO_3160
symbol: rfbc
gene_biotype: protein_coding
description:
  dTDP-4-keto-L-rhamnose-35-epimerase RfbC; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: SO_3167
symbol: rffG
gene_biotype: protein_coding
description:
  dTDP-glucose-4,6-dehydratase RffG; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: SO_3186
symbol: rmlA
gene_biotype: protein_coding
description:
  Glucose-1-phosphate-thymidylyltransferase RmlA; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: SO_3190
symbol: wbpA
gene_biotype: protein_coding
description:
  UDP-N-acetyl-d-glucosamine 6-dehydrogenase WbpA; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: SO_3194
symbol: rfaH
gene_biotype: protein_coding
description:
  Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family.


ensembl_gene_id: SO_3208
symbol: cheZ
gene_biotype: protein_coding
description:
  Chemotaxis signal transduction system CheY phosphatase CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: SO_3210
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase sigma-28 factor for flagellar operon FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: SO_3213
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar export protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: SO_3215
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar export protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: SO_3216
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar export protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: SO_3217
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar export protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: SO_3218
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar export protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: SO_3220
symbol: fliN
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing component FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: SO_3221
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing component FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: SO_3222
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar basal body protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: SO_3227
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing component FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: SO_3228
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar basal-body MS-ring and collar protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: SO_3230
symbol: flrC
gene_biotype: protein_coding
description:
  Two-component system, response regulator FlrC; Two component signal transduction system controlling flagella biosynthesis Sigma54-dependent response regulator FlrC.


ensembl_gene_id: SO_3231
symbol: flrB
gene_biotype: protein_coding
description:
  Two-component system, sensor histidine kinase FlrB; Two component signal transduction system controlling flagellar biosynthesis histidine kinase with PAS sensory domain FlrB.


ensembl_gene_id: SO_3235
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar filament capping protein FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: SO_3237
symbol: fliC
gene_biotype: protein_coding
description:
  Flagellin FliC; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: SO_3240
symbol: flgK
gene_biotype: protein_coding
description:
  Flagellar hook-filament junction protein FlgK; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: SO_3242
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein FlgI; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: SO_3243
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein FlgH; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: SO_3244
symbol: flgG
gene_biotype: protein_coding
description:
  Flagellar component of cell-distal portion of basal-body rod FlgG; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: SO_3245
symbol: flgF
gene_biotype: protein_coding
description:
  Flagellar component of cell-proximal portion of basal-body rod FlgF; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: SO_3248
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar hook assembly protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: SO_3250
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: SO_3253
symbol: flgA
gene_biotype: protein_coding
description:
  Assembly protein for flagellar basal-body P ring FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: SO_3287
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: SO_3288
symbol: mltF
gene_biotype: protein_coding
description:
  Membrane bound lytic transglycosylase MltF; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: SO_3291
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-specific adenosine deaminase TadA; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: SO_3293
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: SO_3294
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit XseA; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: SO_3308
symbol: der
gene_biotype: protein_coding
description:
  50S ribosome assembly GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: SO_3309
symbol: bamB
gene_biotype: protein_coding
description:
  Beta barrel protein translocation lipoprotein component BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: SO_3312
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: SO_3315
symbol: rlmN
gene_biotype: protein_coding
description:
  23S rRNA (adenine2503-C2)-methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: SO_3341
symbol: tpx
gene_biotype: protein_coding
description:
  Thiol peroxidase Tpx; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: SO_3347
symbol: yqgF
gene_biotype: protein_coding
description:
  Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.


ensembl_gene_id: SO_3352
symbol: yggS
gene_biotype: protein_coding
description:
  PLP-dependent amino acid racemase YggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: SO_3354
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: SO_3358
symbol: yggV
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase YggV; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: SO_3359
symbol: yggW
gene_biotype: protein_coding
description:
  Radical SAM superfamily protein YggW; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: SO_3367
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase TrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: SO_3369
symbol: yggX
gene_biotype: protein_coding
description:
  Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: SO_3411
symbol: SO_3411
gene_biotype: protein_coding
description:
  Predicted non-catalytic member of peptidase subfamily S41B; Degrades oligopeptides; Belongs to the peptidase S41B family.


ensembl_gene_id: SO_3414
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase ThrB; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: SO_3415
symbol: thrA
gene_biotype: protein_coding
description:
  Bifunctional aspartokinase I / homoserine dehydrogenase I ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: SO_3424
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: SO_3426
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: SO_3428
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase AlaS; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: SO_3430
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: SO_3431
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: SO_3432
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase sigma-38 factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: SO_3434
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate O-methyltransferase Pcm; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: SO_3435
symbol: surE
gene_biotype: protein_coding
description:
  5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: SO_3436
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine13 synthase TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: SO_3437
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 24-cyclodiphosphate synthase IspF; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).


ensembl_gene_id: SO_3438
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: SO_3439
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: SO_3440
symbol: eno
gene_biotype: protein_coding
description:
  Enolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: SO_3441
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: SO_3455
symbol: relA
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: SO_3456
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: SO_3457
symbol: barA
gene_biotype: protein_coding
description:
  Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA.


ensembl_gene_id: SO_3460
symbol: lldR
gene_biotype: protein_coding
description:
  Transcriptional regulator of L-lactate utilization LldR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_3463
symbol: pgpA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A PgpA; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: SO_3464
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-phosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: SO_3465
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: SO_3466
symbol: ribE
gene_biotype: protein_coding
description:
  Riboflavin synthase beta subunit RibE; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: SO_3467
symbol: ribBA
gene_biotype: protein_coding
description:
  Bifunctional 34-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: SO_3469
symbol: ribD
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: SO_3470
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional repressor of deoxyribonucleotide biosynthesis NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: SO_3471
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: SO_3493
symbol: mexE
gene_biotype: protein_coding
description:
  HAE1 family efflux pump MFP component MexE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_3497
symbol: aptA
gene_biotype: protein_coding
description:
  Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: SO_3505
symbol: nagA
gene_biotype: protein_coding
description:
  N-acetylglucosamine-6-phosphate deacetylase NagA; Belongs to the metallo-dependent hydrolases superfamily. NagA family.


ensembl_gene_id: SO_3529
symbol: ispH
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase IspH; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: SO_3531
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II LspA; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: SO_3532
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase IleS; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: SO_3534
symbol: murJ
gene_biotype: protein_coding
description:
  Peptidoglycan lipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: SO_3546
symbol: talB
gene_biotype: protein_coding
description:
  Transaldolase B TalB; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: SO_3554
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: SO_3555
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: SO_3559
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase GshA; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: SO_3562
symbol: SO_3562
gene_biotype: protein_coding
description:
  Proton/sodium:glutamate symporter DAACS family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: SO_3565
symbol: cpdB
gene_biotype: protein_coding
description:
  Bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3`-nucleotidase CpdB; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: SO_3575
symbol: pssA-2
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase PssA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: SO_3577
symbol: clpB
gene_biotype: protein_coding
description:
  Stress-induced multi-chaperone system component ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to [...]


ensembl_gene_id: SO_3579
symbol: rluD
gene_biotype: protein_coding
description:
  23S rRNA pseudouridine1911/1915/1917 synthase RluD; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: SO_3580
symbol: bamC
gene_biotype: protein_coding
description:
  Beta barrel protein translocation lipoprotein component BamC; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: SO_3600
symbol: cysT
gene_biotype: protein_coding
description:
  ABC-type sulfate/thiosulfate uptake system permease component 1 CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SO_3602
symbol: cysA
gene_biotype: protein_coding
description:
  ABC-type sulfate/thiosulfate uptake system ATPase component CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SO_3613
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2 PurT; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: SO_3631
symbol: hprA
gene_biotype: protein_coding
description:
  NADH-dependent hydroxypyruvate reductase HprA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: SO_3633
symbol: djlA
gene_biotype: protein_coding
description:
  DnaK co-chaperone DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: SO_3636
symbol: lptD
gene_biotype: protein_coding
description:
  Lipopolysaccharide export porin LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: SO_3637
symbol: surA
gene_biotype: protein_coding
description:
  Outer membrane protein maturation factor peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: SO_3638
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxy-L-threonine phosphate dehydrogenase PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: SO_3639
symbol: rsmA
gene_biotype: protein_coding
description:
  16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase RsmA; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: SO_3641
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5-nucleosyl)-tetraphosphatase ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: SO_3646
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: SO_3649
symbol: obgE
gene_biotype: protein_coding
description:
  50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: SO_3652
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: SO_3654
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase Ung; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: SO_3674
symbol: hmuC
gene_biotype: protein_coding
description:
  ABC-type hemin uptake system permease component HmuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: SO_3675
symbol: hmuD
gene_biotype: protein_coding
description:
  ABC-type hemin uptake system ATPase component HmuD; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SO_3695
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase homodimeric type PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.


ensembl_gene_id: SO_3706
symbol: nupX
gene_biotype: protein_coding
description:
  Nucleoside:proton symporter NupX; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: SO_3726
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase large subunit CysN; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: SO_3735
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase MtgA; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: SO_3736
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenylyl-sulfate reductase thioredoxin-dependent CysH; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: SO_3737
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) siroheme FeS subunit CysI; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: SO_3738
symbol: cysJ
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) flavoprotein subunit CysJ; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: SO_3740
symbol: pntA
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase alpha subunit PntA; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: SO_3741
symbol: pntB
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase beta subunit PntB; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: SO_3745
symbol: rfaE
gene_biotype: protein_coding
description:
  Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.


ensembl_gene_id: SO_3746
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl acyltransferase LpxL; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: SO_3747
symbol: khaP
gene_biotype: protein_coding
description:
  K+:H+ antiporter KhaP; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.


ensembl_gene_id: SO_3757
symbol: SO_3757
gene_biotype: protein_coding
description:
  Transcriptional regulator of bicarbonate utilization LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_3760
symbol: glnE
gene_biotype: protein_coding
description:
  [glutamate-ammonia-ligase] adenylyltransferase GlnE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal [...]


ensembl_gene_id: SO_3763
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase SpeE; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: SO_3774
symbol: putA-2
gene_biotype: protein_coding
description:
  Bifunctional proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: SO_3783
symbol: rhlE
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: SO_3789
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase SufS; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: SO_3798
symbol: rluA
gene_biotype: protein_coding
description:
  23S rRNA pseudouridine746 synthase RluA; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: SO_3803
symbol: hprT
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase HprT; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: SO_3804
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate decarboxylase UbiX; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: SO_3805
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase Mpl; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: SO_3812
symbol: ppiA
gene_biotype: protein_coding
description:
  Periplasmic peptidyl-prolyl cis-trans isomerase PpiA; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: SO_3817
symbol: panE
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: SO_3832
symbol: prmC
gene_biotype: protein_coding
description:
  Peptide release factor glutamine N5-methylase PrmC; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: SO_3833
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1 PrfA; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: SO_3834
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: SO_3835
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: SO_3836
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2C-methyl-D-erythritol kinase IspE; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: SO_3837
symbol: prsA
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase PrsA; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: SO_3855
symbol: sfcA
gene_biotype: protein_coding
description:
  NAD-dependent malate dehydrogenase (oxaloacetate-decarboxylating) SfcA; Belongs to the malic enzymes family.


ensembl_gene_id: SO_3861
symbol: yjeS
gene_biotype: protein_coding
description:
  4Fe-4S binding protein YjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: SO_3864
symbol: modB
gene_biotype: protein_coding
description:
  ABC-type molybdate uptake system permease component ModB; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SO_3865
symbol: modC
gene_biotype: protein_coding
description:
  ABC-type molybdate uptake system ATPase component ModC; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: SO_3870
symbol: dsbI
gene_biotype: protein_coding
description:
  Disulfide bond formation protein DsbB family; Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT (By similarity).


ensembl_gene_id: SO_3897
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV A subunit ParC; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: SO_3899
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV B subunit ParE; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: SO_3901
symbol: cpdA
gene_biotype: protein_coding
description:
  Cyclic 3', 5'-adenosine monophosphate phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: SO_3912
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA2fMet-dihydrouridine21 synthase DusA; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: SO_3916
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase biosynthetic Alr; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: SO_3917
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: SO_3928
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18 RpsR; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: SO_3929
symbol: priB
gene_biotype: protein_coding
description:
  Primosomal replication protein N PriB; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: SO_3934
symbol: rlmB
gene_biotype: protein_coding
description:
  23S rRNA (guanosine2251-2'-O)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: SO_3935
symbol: rnr
gene_biotype: protein_coding
description:
  3'-5' exoribonuclease R Rnr; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: SO_3937
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: SO_3940
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13 RplM; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: SO_3948
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: SO_3957
symbol: kdsC
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate-8-phosphatase KdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: SO_3958
symbol: lptC
gene_biotype: protein_coding
description:
  ABC-type lipopolysaccharide export system MFP component LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: SO_3959
symbol: lptA
gene_biotype: protein_coding
description:
  ABC-type lipopolysaccharide export system chaperone component LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: SO_3961
symbol: rpoN
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: SO_3980
symbol: nrfA
gene_biotype: protein_coding
description:
  Ammonia-forming nitrite reductase NrfA; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process. Has very low activity toward hydroxylamine. Has even lower activity toward sulfite. Sulfite reductase activity is maximal at neutral pH (By similarity); Belongs to the cytochrome c-552 family.


ensembl_gene_id: SO_4002
symbol: SO_4002
gene_biotype: protein_coding
description:
  Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain.


ensembl_gene_id: SO_4014
symbol: SO_4014
gene_biotype: protein_coding
description:
  HAE1 family effllux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_4015
symbol: SO_4015
gene_biotype: protein_coding
description:
  HAE1 family effllux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_4028
symbol: ssb
gene_biotype: protein_coding
description:
  Single-strand binding protein Ssb; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: SO_4030
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC A subunit UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: SO_4034
symbol: deaD
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase DeaD; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: SO_4054
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase MetF; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: SO_4055
symbol: metL
gene_biotype: protein_coding
description:
  Bifunctional aspartokinase II/homoserine dehydrogenase methionine-sensitive MetL; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: SO_4057
symbol: metJ
gene_biotype: protein_coding
description:
  Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.


ensembl_gene_id: SO_4061
symbol: phsB
gene_biotype: protein_coding
description:
  Sulfur reductase FeS subunit PhsB; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: SO_4062
symbol: phsA
gene_biotype: protein_coding
description:
  Sulfur reductase molybdoperterin-binding subunit PhsA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SO_4066
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family.


ensembl_gene_id: SO_4072
symbol: rimO
gene_biotype: protein_coding
description:
  Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: SO_4095
symbol: yhdE
gene_biotype: protein_coding
description:
  Maf septum formation family protein YhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: SO_4096
symbol: mreD
gene_biotype: protein_coding
description:
  Cell wall structural complex component MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: SO_4122
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal replication protein N' PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: SO_4133
symbol: udp
gene_biotype: protein_coding
description:
  Uridine phosphorylase Udp; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: SO_4141
symbol: SO_4141
gene_biotype: protein_coding
description:
  Oxidoreductase short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: SO_4155
symbol: ttrS
gene_biotype: protein_coding
description:
  Thiosulfate/tetrathionate-responsive two component signal transduction system histidine kinase TtrS.


ensembl_gene_id: SO_4157
symbol: ttrR
gene_biotype: protein_coding
description:
  Two-component system, LuxR family, response regulator TtrR; Thiosulfate/tetrathionate-responsive two component signal transduction system response regulator TtrR.


ensembl_gene_id: SO_4162
symbol: hslV
gene_biotype: protein_coding
description:
  HlsVU protease peptidase component HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: SO_4163
symbol: hslU
gene_biotype: protein_coding
description:
  HlsVU protease ATPase component HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: SO_4172
symbol: prrA
gene_biotype: protein_coding
description:
  Two-component system, response regulator RegA; Oxygen-responsive two component signal transduction system controlling redox affected systems response regulator PrrA.


ensembl_gene_id: SO_4173
symbol: prrB
gene_biotype: protein_coding
description:
  Two-component system, sensor histidine kinase RegB; Oxygen-responsive two component signal transduction system controlling redox affected systems histidine kinase PrrB.


ensembl_gene_id: SO_4197
symbol: rraA
gene_biotype: protein_coding
description:
  Ribonuclease E inhibitor RraA; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: SO_4199
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: SO_4201
symbol: ubiB
gene_biotype: protein_coding
description:
  2-polyprenylphenol 6-hydroxylase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: SO_4202
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine protein translocase system protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: SO_4203
symbol: tatB
gene_biotype: protein_coding
description:
  Twin arginine protein translocase system protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: SO_4204
symbol: tatC
gene_biotype: protein_coding
description:
  Twin arginine protein translocase system protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: SO_4211
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase ATPase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: SO_4214
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-0-acyl N-acetylglucosamine deacetylase LpxC; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: SO_4215
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division filament FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: SO_4216
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: SO_4217
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: SO_4219
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase MurG; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: SO_4220
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: SO_4221
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: SO_4222
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: SO_4223
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: SO_4224
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase MurE; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: SO_4225
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: SO_4226
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: SO_4227
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA (cytosine1402-N4)-methyltransferase RsmH; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: SO_4230
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: SO_4233
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit LeuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: SO_4234
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit LeuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: SO_4235
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.


ensembl_gene_id: SO_4236
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: SO_4249
symbol: dfp
gene_biotype: protein_coding
description:
  Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: SO_4250
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: SO_4251
symbol: slmA
gene_biotype: protein_coding
description:
  Transcriptional repressor of cell division SlmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: SO_4255
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: SO_4256
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH Rph; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: SO_4266
symbol: mloA
gene_biotype: protein_coding
description:
  Fic family protein MloA; Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.


ensembl_gene_id: SO_4283
symbol: SO_4283
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: SO_4289
symbol: pstB2
gene_biotype: protein_coding
description:
  ABC-type phosphate uptake system permease ATPase component PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: SO_4291
symbol: pstC-2
gene_biotype: protein_coding
description:
  ABC-type phosphate uptake system permease component PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SO_4302
symbol: dnrN
gene_biotype: protein_coding
description:
  Repair of iron centers (RIC) protein DnrN; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: SO_4306
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: SO_4308
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase DapF; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: SO_4309
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: SO_4311
symbol: cyaY
gene_biotype: protein_coding
description:
  Iron donor for FeS cluster assembly CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: SO_4313
symbol: hemC
gene_biotype: protein_coding
description:
  Hydroxymethylbilane synthase HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: SO_4314
symbol: hemD
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase HemD; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: SO_4325
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: SO_4327
symbol: vexB
gene_biotype: protein_coding
description:
  RND-type multidrug/detergent efflux system MFP component VexB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_4328
symbol: vexA
gene_biotype: protein_coding
description:
  RND-type multidrug/detergent efflux system permease component VexA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_4344
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: SO_4349
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase IlvC; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: SO_4350
symbol: ilvY
gene_biotype: protein_coding
description:
  LysR family transcriptional regulator, positive regulator for ilvC; Acetohydroxybutyrate/acetolactate-responsive transcriptional regulator of isoleucine-valine biosynthesis IlvY; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: SO_4358
symbol: SO_4358
gene_biotype: protein_coding
description:
  Extracellular oxidoreductase molybdopterin-binding lipoprotein subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SO_4364
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: SO_4369
symbol: acpP-2
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: SO_4376
symbol: SO_4376
gene_biotype: protein_coding
description:
  Uncharacterized protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: SO_4380
symbol: SO_4380
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SO_4383
symbol: fabF-2
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase II FabF; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: SO_4396
symbol: azoR
gene_biotype: protein_coding
description:
  FMN-dependent NADH-azoreductase AzoR; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: SO_4398
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase Dtd; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: SO_4417
symbol: dcuB
gene_biotype: protein_coding
description:
  Anaerobic C4-dicarboxylate transporter DcuB; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: SO_4444
symbol: rcsB
gene_biotype: protein_coding
description:
  Two-component system, NarL family, captular synthesis response regulator RcsB; Two component signal transduction system response regulator of capsule flagella and curli biosynthesis RcsB.


ensembl_gene_id: SO_4451
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: SO_4452
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: SO_4453
symbol: etfQ
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase EtfQ; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: SO_4467
symbol: ppnP
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: SO_4471
symbol: glnL
gene_biotype: protein_coding
description:
  Nitrogen-responsive two component signal transduction system histidine kinase with PAS sensory domain GlnL.


ensembl_gene_id: SO_4472
symbol: glnG
gene_biotype: protein_coding
description:
  DNA-binding transcriptional regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: SO_4475
symbol: fieF
gene_biotype: protein_coding
description:
  Cadmium and zinc efflux pump FieF; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: SO_4487
symbol: SO_4487
gene_biotype: protein_coding
description:
  Two component signal transduction system response regulator with winged helix family DNA binding domain.


ensembl_gene_id: SO_4503
symbol: fdhD-2
gene_biotype: protein_coding
description:
  Formate dehydrogenase assembly/maturation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: SO_4509
symbol: fdhA
gene_biotype: protein_coding
description:
  Formate dehydrogenase molybdopterin-binding subunit FdhA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SO_4513
symbol: fdhA-2
gene_biotype: protein_coding
description:
  Fnr-inducilble formate dehydrogenase molybdopterin-binding subunit FdhA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: SO_4529
symbol: trmL
gene_biotype: protein_coding
description:
  tRNA (cytidine34-2'-O)-methyltransferase TrmL; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: SO_4564
symbol: tonB-3
gene_biotype: protein_coding
description:
  TonB mediated energy transduction system energy transducer component TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: SO_4573
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase MenD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).


ensembl_gene_id: SO_4574
symbol: menH
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-24-cyclohexadiene-1- carboxylate synthase MenH; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: SO_4575
symbol: menC
gene_biotype: protein_coding
description:
  O-succinylbenzoate-CoA synthase MenC; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: SO_4583
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma-32 factor RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: SO_4584
symbol: ftsX
gene_biotype: protein_coding
description:
  ABC-type cell division-associated export system permease component FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: SO_4585
symbol: ftsE
gene_biotype: protein_coding
description:
  ABC-type cell division-associated export system ATPase component FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: SO_4586
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: SO_4587
symbol: rsmD
gene_biotype: protein_coding
description:
  16S rRNA (guanine966-N2)-methyltransferase RsmD; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: SO_4597
symbol: cusB
gene_biotype: protein_coding
description:
  Copper/silver efflux pump MFP component CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_4598
symbol: cusA
gene_biotype: protein_coding
description:
  Copper/silver efflux pump permease component CusA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: SO_4603
symbol: lexA
gene_biotype: protein_coding
description:
  Bifunctional transcriptional repressor of SOS-response/self-cleaving protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: SO_4604
symbol: sulA
gene_biotype: protein_coding
description:
  UV induced cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: SO_4606
symbol: coxB
gene_biotype: protein_coding
description:
  Aa3-type cytochrome c oxidase subunit II CoxB; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: SO_4607
symbol: coxA
gene_biotype: protein_coding
description:
  Aa3 type cytochrome c oxidase subunit I CoxA; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: SO_4614
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase (heme O synthase) CtaB; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: SO_4619
symbol: nfuA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster biogenesis scaffold protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: SO_4620
symbol: urdA
gene_biotype: protein_coding
description:
  FAD-dependent oxidoreductase; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate [...]


ensembl_gene_id: SO_4626
symbol: bioH
gene_biotype: protein_coding
description:
  Biotin biosynthesis carboxylesterase BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: SO_4631
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: SO_4640
symbol: SO_4640
gene_biotype: protein_coding
description:
  Antioxidant AhpC/Tsa family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: SO_4642
symbol: SO_4642
gene_biotype: protein_coding
description:
  Toxin-antitoxin system antidote Phd family; Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: SO_4653
symbol: cysT-2
gene_biotype: protein_coding
description:
  ABC-type sulfate/thiosulfate uptakesystem permease component 1 CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: SO_4655
symbol: cysA2
gene_biotype: protein_coding
description:
  ABC-type sulfate/thiosulfate uptakesystem ATPase component CysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: SO_4657
symbol: SO_4657
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with PAS and LOV sensory domains and Chase small molecule binding site.


ensembl_gene_id: SO_4658
symbol: rsmJ
gene_biotype: protein_coding
description:
  16S rRNA (guanine1516-G2)-methyltransferase RsmJ; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: SO_4659
symbol: yhiR
gene_biotype: protein_coding
description:
  Exogenous DNA processing protein YhiR; Specifically methylates the adenine in position 2030 of 23S rRNA.


ensembl_gene_id: SO_4667
symbol: yihA
gene_biotype: protein_coding
description:
  50S ribosome assembly GTPase YihA; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: SO_4669
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: SO_4670
symbol: elbB
gene_biotype: protein_coding
description:
  Isoprenoid biosynthesis protein ElbB; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: SO_4672
symbol: glpE
gene_biotype: protein_coding
description:
  Thiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: SO_4673
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase Tdh; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: SO_4674
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase Kbl; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: SO_4676
symbol: kdtA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonic-acid (KDO) transferase KdtA; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: SO_4677
symbol: kdkA
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-oct-2-ulosonic acid (KDO) kinase KdkA; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: SO_4684
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: SO_4693
symbol: vmeA
gene_biotype: protein_coding
description:
  Proton-coupled multidrug efflux pump MFP component VmeA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: SO_4713
symbol: menF
gene_biotype: protein_coding
description:
  Menaquinone-specific isochorismate synthase MenF; Catalyzes the conversion of chorismate to isochorismate.


ensembl_gene_id: SO_4715
symbol: SO_4715
gene_biotype: protein_coding
description:
  Membrane protein of unknown function DUF165; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: SO_4718
symbol: SO_4718
gene_biotype: protein_coding
description:
  Tungstate-responsive two component Sigma54-dependent signal transduction system response regulator Fis family.


ensembl_gene_id: SO_4722
symbol: mobA
gene_biotype: protein_coding
description:
  Tungstopterin-guanine dinucleotide biosynthesis protein A MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: SO_4723
symbol: mobB/moeA
gene_biotype: protein_coding
description:
  Bifunctional tungstopterin-guanine dinucleotide biosynthesis protein MobB/MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: SO_4724
symbol: moaA-2
gene_biotype: protein_coding
description:
  Tungsten cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: SO_4726
symbol: mutM-2
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase MutM; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: SO_4728
symbol: yihI
gene_biotype: protein_coding
description:
  GAP-like protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: SO_4730
symbol: hemN
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase oxygen-independent HemN; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: SO_4731
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase Add; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: SO_4739
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase MenB; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.


ensembl_gene_id: SO_4741
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: SO_4745
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: SO_4746
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase F1 epsilon subunit AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: SO_4747
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1 beta subunit AtpD; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: SO_4748
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase F1 gamma subunit AtpG; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: SO_4749
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase F1 alpha subunit AtpA; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: SO_4750
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase F1 delta subunit AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: SO_4751
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0 B subunit AtpF; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: SO_4752
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0 C subunit AtpE; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: SO_4753
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0 A subunit AtpB; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: SO_4757
symbol: rsmG
gene_biotype: protein_coding
description:
  16S rRNA (guanine527-N7)-methyltransferase RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: SO_4758
symbol: mnmG
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification system MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: SO_4778
symbol: sdhD
gene_biotype: protein_coding
description:
  Succinate dehydrogenase membrane anchor subunit SdhD; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


