# pathwayInfo

id: SM00963
description: SRP54-type protein, helical bundle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00969
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00969
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00969_The_SOCS_box_acts_as_a_bridge_between_specific_substrate-_binding_domains_and_more_generic_proteins_that_comprise_a_large_family_of_E3_ubiquitin_protein_ligases.

description:
  The SOCS box acts as a bridge between specific substrate- binding domains and more generic proteins that comprise a large family of E3 ubiquitin protein ligases.


id: SM00978
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00978
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00978_Tim44_is_an_essential_component_of_the_machinery_that_mediates_the_translocation_of_nuclear-encoded_proteins_across_the_mitochondrial_inner_membrane_PUBMED:10430866._Tim44_is_thought_to_bind_phospholipids_of_the_mitochondrial_inner_membrane_both_by_...

description:
  Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane PUBMED:10430866. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by ...


id: SM00980
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00980
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00980_The_THAP_domain_is_a_putative_DNA-binding_domain_(DBD)_and_probably_also_binds_a_zinc_ion._It_features_the_conserved_C2CH_architecture_(consensus_sequence:_Cys_-_2-4_residues_-_Cys_-_35-50_residues_-_Cys_-_2_residues_-_His)._Other_universal_features_...

description:
  The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features ...


id: SM00981
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00983
description: Thiamin pyrophosphokinase, vitamin B1 binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00983
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00983_Thiamin_pyrophosphokinase,_vitamin_B1_binding_domain


id: SM00985
description: Ubiquitin-activating enzyme e1 C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00985
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00985_Ubiquitin-activating_enzyme_e1_C-terminal_domain


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00990
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00990
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00990_This_entry_contains_proteins_with_the_VRR-NUC_domain._It_is_associated_with_members_of_the_PD-(D/E)XK_nuclease_superfamily,_which_include_the_type_III_restriction_modification_enzymes,_for_example_StyLTI.

description:
  This entry contains proteins with the VRR-NUC domain. It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes, for example StyLTI.


id: SM00991
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00991
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00991_A_conserved_domain_of_46_amino_acids,_called_WHEP-TRS_has_been_shown_PUBMED:1756734_to_exist_in_a_number_of_higher_eukaryote_aminoacyl-transfer_RNA_synthetases._This_domain_is_present_one_to_six_times_in_the_several_enzymes._There_are_three_copies_in_...

description:
  A conserved domain of 46 amino acids, called WHEP-TRS has been shown PUBMED:1756734 to exist in a number of higher eukaryote aminoacyl-transfer RNA synthetases. This domain is present one to six times in the several enzymes. There are three copies in ...


id: SM00992
description: Hemimethylated DNA-binding protein YccV like
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00992
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00992_Hemimethylated_DNA-binding_protein_YccV_like


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01008
description: Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01008
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01008_Aldehyde_oxidase_and_xanthine_dehydrogenase,_a/b_hammerhead_domain


id: SM01010
description: 5-AMP-activated protein kinase beta subunit, interation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01010
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01010_5-AMP-activated_protein_kinase_beta_subunit,_interation_domain


id: SM01013
description: Anaphase promoting complex (APC) subunit 2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01013
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01013_Anaphase_promoting_complex_(APC)_subunit_2


id: SM01017
description: Arrestin (or S-antigen), C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01017
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01017_Arrestin_(or_S-antigen),_C-terminal_domain


id: SM01020
description: Beta2-adaptin appendage, C-terminal sub-domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01020
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01020_Beta2-adaptin_appendage,_C-terminal_sub-domain


id: SM01024
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01024
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01024_This_domain_is_found_at_the_N_terminal_of_the_mitochondrial_ATPase_BSC1._It_encodes_the_import_and_intramitochondrial_sorting_for_the_protein.

description:
  This domain is found at the N terminal of the mitochondrial ATPase BSC1. It encodes the import and intramitochondrial sorting for the protein.


id: SM01025
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01025
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01025_The_BEN_domain_is_found_in_diverse_animal_proteins_such_as_BANP/SMAR1,_NAC1_and_the_Drosophila_mod(mdg4)_isoform_C,_in_the_chordopoxvirus_virosomal_protein_E5R_and_in_several_proteins_of_polydnaviruses._Computational_analysis_suggests_that_the_BEN_...

description:
  The BEN domain is found in diverse animal proteins such as BANP/SMAR1, NAC1 and the Drosophila mod(mdg4) isoform C, in the chordopoxvirus virosomal protein E5R and in several proteins of polydnaviruses. Computational analysis suggests that the BEN ...


id: SM01039
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01039
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01039_The_BRICHOS_domain_is_about_100_amino_acids_long._It_is_found_in_a_variety_of_proteins_implicated_in_dementia,_respiratory_distress_and_cancer._Its_exact_function_is_unknown

description:
  The BRICHOS domain is about 100 amino acids long. It is found in a variety of proteins implicated in dementia, respiratory distress and cancer. Its exact function is unknown


id: SM01050
description: Cactus-binding C-terminus of cactin protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01050
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01050_Cactus-binding_C-terminus_of_cactin_protein


id: SM01051
description: Microtubule-binding calmodulin-regulated spectrin-associated
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01051
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01051_Microtubule-binding_calmodulin-regulated_spectrin-associated


id: SM01052
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01052
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01052_Cytoskeleton-associated_proteins_(CAPs)_are_involved_in_the_organisation_of_microtubules_and_transportation_of_vesicles_and_organelles_along_the_cytoskeletal_network._A_conserved_motif,_CAP-Gly,_has_been_identified_in_a_number_of_CAPs,_including_...

description:
  Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including ...


id: SM01060
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01062
description: Voltage gated calcium channel IQ domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01062
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01062_Voltage_gated_calcium_channel_IQ_domain


id: SM01072
description: Cell division protein 48 (CDC48) domain 2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01072
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01072_Cell_division_protein_48_(CDC48)_domain_2


id: SM01073
description: Cell division protein 48 (CDC48) N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01073
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01073_Cell_division_protein_48_(CDC48)_N-terminal_domain


id: SM01076
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01076
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01076_CG-1_domains_are_highly_conserved_domains_of_about_130_amino-acid_residues_containing_a_predicted_bipartite_NLS_and_named_after_a_partial_cDNA_clone_isolated_from_parsley_encoding_a_sequence-specific_DNA-binding_protein_PUBMED:8075408._CG-1_domains_...

description:
  CG-1 domains are highly conserved domains of about 130 amino-acid residues containing a predicted bipartite NLS and named after a partial cDNA clone isolated from parsley encoding a sequence-specific DNA-binding protein PUBMED:8075408. CG-1 domains ...


id: SM01077
description: Uncharacterized conserved protein CG6151-P
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01077
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01077_Uncharacterized_conserved_protein_CG6151-P


id: SM01083
description: N-terminal domain of CBF1 interacting co-repressor CIR
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01083
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01083_N-terminal_domain_of_CBF1_interacting_co-repressor_CIR


id: SM01084
description: Cyclin-dependent kinase regulatory subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01084
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01084_Cyclin-dependent_kinase_regulatory_subunit


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01092
description: CO dehydrogenase flavoprotein C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01092
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01092_CO_dehydrogenase_flavoprotein_C-terminal_domain


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01109
description: The CUT domain is a DNA-binding domain often found in combination with a downstream homeodomain.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01109
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01109_The_CUT_domain_is_a_DNA-binding_domain_often_found_in_combination_with_a_downstream_homeodomain.


id: SM01115
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01115
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01115_The_cwf21_family_is_involved_in_mRNA_splicing._It_has_been_isolated_as_a_subcomplex_of_the_splicosome_in_Schizosaccharomyces_pombe_(PUBMED:11884590)._The_function_of_the_cwf21_domain_is_to_bind_directly_to_the_spliceosomal_protein_Prp8._Mutations_in_...

description:
  The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe (PUBMED:11884590). The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in ...


id: SM01117
description: Cytochrome b5-like Heme/Steroid binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01117
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01117_Cytochrome_b5-like_Heme/Steroid_binding_domain


id: SM01118
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01118
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01118_These_sequences_are_functionally_identified_as_members_of_the_adenylate_cyclase_family,_which_catalyses_the_conversion_of_ATP_to_3,5-cyclic_AMP_and_pyrophosphate._Six_distinct_non-homologous_classes_of_AC_have_been_identified._The_structure_of_...

description:
  These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3,5-cyclic AMP and pyrophosphate. Six distinct non-homologous classes of AC have been identified. The structure of ...


id: SM01120
description: This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01120
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01120_This_domain_is_the_predicted_phosphatase_domain_of_the_dihydroxyacetone_kinase_family.


id: SM01124
description: Lariat debranching enzyme, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01124
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01124_Lariat_debranching_enzyme,_C-terminal_domain


id: SM01127
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01127
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01127_The_DDHD_domain_is_180_residues_long_and_contains_four_conserved_residues_that_may_form_a_metal_binding_site._The_domain_is_named_after_these_four_residues._This_pattern_of_conservation_of_metal_binding_residues_is_often_seen_in_phosphoesterase_...

description:
  The DDHD domain is 180 residues long and contains four conserved residues that may form a metal binding site. The domain is named after these four residues. This pattern of conservation of metal binding residues is often seen in phosphoesterase ...


id: SM01128
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01128
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01128_This_is_a_family_of_proteins_of_approximately_300_residues,_found_in_plants_and_vertebrates._They_contain_a_highly_conserved_DDRGK_motif.

description:
  This is a family of proteins of approximately 300 residues, found in plants and vertebrates. They contain a highly conserved DDRGK motif.


id: SM01131
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01131
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01131_This_domain_is_often_found_adjacent_to_the_DHH_domain_PF01368_and_is_called_DHHA2_for_DHH_associated_domain._This_domain_is_diagnostic_of_DHH_subfamily_2_members_(PUBMED:9478130)._The_domain_is_about_120_residues_long_and_contains_a_conserved_DXK_...

description:
  This domain is often found adjacent to the DHH domain PF01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members (PUBMED:9478130). The domain is about 120 residues long and contains a conserved DXK ...


id: SM01135
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01135
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01135_DIRP_(Domain_in_Rb-related_Pathway)_is_postulated_to_be_involved_in_the_Rb-related_pathway,_which_is_encoded_by_multiple_eukaryotic_genomes_and_is_present_in_proteins_including_lin-9_of_Caenorhabditis_elegans,_aly_of_fruit_fly_and_mustard_weed._...

description:
  DIRP (Domain in Rb-related Pathway) is postulated to be involved in the Rb-related pathway, which is encoded by multiple eukaryotic genomes and is present in proteins including lin-9 of Caenorhabditis elegans, aly of fruit fly and mustard weed. ...


id: SM01142
description: This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases [PUBMED:15112237].
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01142
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01142_This_C_terminal_domain_is_found_in_DOB1/SK12/helY-like_DEAD_box_helicases_[PUBMED:15112237].


id: SM01144
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01144
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01144_This_presumed_domain_is_found_in_bacterial_and_eukaryotic_proteins._Its_function_is_unknown._The_domain_contains_multiple_conserved_motifs_including_a_DTXW_motif_that_this_domain_has_been_named_after.

description:
  This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.


id: SM01147
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01147
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01147_Members_of_this_family_are_found_in_various_chromatin_remodelling_factors_and_transposases._Their_exact_function_is,_as_yet,_unknown.

description:
  Members of this family are found in various chromatin remodelling factors and transposases. Their exact function is, as yet, unknown.


id: SM01156
description: Eukaryotic domain of unknown function (DUF1716)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01156
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01156_Eukaryotic_domain_of_unknown_function_(DUF1716)


id: SM01158
description: This is a eukaryotic domain of unknown function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01158
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01158_This_is_a_eukaryotic_domain_of_unknown_function.


id: SM01160
description: Eukaryotic integral membrane protein (DUF1751)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01160
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01160_Eukaryotic_integral_membrane_protein_(DUF1751)


id: SM01161
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01161
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01161_Eukaryotic_domain_of_unknown_function._This_domain_is_found_to_the_N-terminus_of_the_nucleic_acid_binding_domain.

description:
  Eukaryotic domain of unknown function. This domain is found to the N-terminus of the nucleic acid binding domain.


id: SM01163
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01163
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01163_This_region_is_found_in_argonaute_[PUBMED:16216572]_proteins_and_often_co-occurs_with_BAG_(SM00264)_and_Piwi_(SM00950).

description:
  This region is found in argonaute [PUBMED:16216572] proteins and often co-occurs with BAG (SM00264) and Piwi (SM00950).


id: SM01165
description: This domain, found in Synaptojanin, has no known function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01165
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01165_This_domain,_found_in_Synaptojanin,_has_no_known_function.


id: SM01166
description: This set of domains is found in various eukaryotic proteins. Function is unknown.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01166
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01166_This_set_of_domains_is_found_in_various_eukaryotic_proteins._Function_is_unknown.


id: SM01167
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01167
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01167_This_domain_is_predominantly_found_in_the_structural_protein_coronin,_and_is_duplicated_in_some_sequences._It_has_no_known_function_[PUBMED:16172398].

description:
  This domain is predominantly found in the structural protein coronin, and is duplicated in some sequences. It has no known function [PUBMED:16172398].


id: SM01168
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01168
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01168_The_structure_of_this_domain_displays_an_alpha-beta-beta-alpha_four_layer_topology,_with_an_HxHxxxxxxxxxH_motif_that_coordinates_a_zinc_ion,_and_an_acetate_anion_at_a_site_that_likely_supports_the_enzymatic_activity_of_an_ester_hydrolase_...

description:
  The structure of this domain displays an alpha-beta-beta-alpha four layer topology, with an HxHxxxxxxxxxH motif that coordinates a zinc ion, and an acetate anion at a site that likely supports the enzymatic activity of an ester hydrolase ...


id: SM01169
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01169
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01169_Members_of_this_family_adopt_a_structure_consisting_of_several_large_open_beta-sheets._Their_exact_function_has_not,_as_yet,_been_determined_[PUBMED:12135361].

description:
  Members of this family adopt a structure consisting of several large open beta-sheets. Their exact function has not, as yet, been determined [PUBMED:12135361].


id: SM01173
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01173
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01173_This_family_is_found_at_the_very_C-terminus_of_proteins_that_carry_a_G-patch_domain_SM00443._The_domain_is_short_and_cysteine-rich_.

description:
  This family is found at the very C-terminus of proteins that carry a G-patch domain SM00443. The domain is short and cysteine-rich .


id: SM01175
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01175
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01175_This_is_a_family_of_cysteine-rich_proteins._Many_members_also_carry_a_pleckstrin-homology_domain,SM00233.

description:
  This is a family of cysteine-rich proteins. Many members also carry a pleckstrin-homology domain,SM00233.


id: SM01177
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01177
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01177_This_short_domain_is_found_in_fungi,_plants_and_animals,_and_the_proteins_appear_to_be_necessary_for_chromosome_segregation_during_meiosis.

description:
  This short domain is found in fungi, plants and animals, and the proteins appear to be necessary for chromosome segregation during meiosis.


id: SM01178
description: This short domain is found at the C-terminus of many helicase proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01178
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01178_This_short_domain_is_found_at_the_C-terminus_of_many_helicase_proteins.


id: SM01181
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01181
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01181_E1_and_E2_enzymes_play_a_central_role_in_ubiquitin_and_ubiquitin-like_protein_transfer_cascades._This_is_an_E2_binding_domain_that_is_found_on_NEDD8_activating_E1_enzyme._The_domain_resembles_ubiquitin,_and_recruits_the_catalytic_core_of_the_E2_...

description:
  E1 and E2 enzymes play a central role in ubiquitin and ubiquitin-like protein transfer cascades. This is an E2 binding domain that is found on NEDD8 activating E1 enzyme. The domain resembles ubiquitin, and recruits the catalytic core of the E2 ...


id: SM01182
description: Eukaryotic elongation factor 1 beta central acidic region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01182
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01182_Eukaryotic_elongation_factor_1_beta_central_acidic_region


id: SM01183
description: Elongation factor 1 gamma, conserved domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01183
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01183_Elongation_factor_1_gamma,_conserved_domain


id: SM01189
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01189
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01189_The_ELM2_(Egl-27_and_MTA1_homology_2)_domain_is_a_small_domain_of_unknown_function._It_is_found_in_the_MTA1_protein_that_is_part_of_the_NuRD_complex_PUBMED:10226007._The_domain_is_usually_found_to_the_N_terminus_of_a_myb-like_DNA_binding_domain_SANT_...

description:
  The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex PUBMED:10226007. The domain is usually found to the N terminus of a myb-like DNA binding domain SANT ...


id: SM01191
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01191
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01191_This_presumed_domain_is_named_after_Emsy_N_Terminus_(ENT)._Emsy_is_a_protein_that_is_amplified_in_breast_cancer_and_interacts_with_BRCA2._The_N_terminus_of_this_protein_is_found_to_be_similar_to_other_vertebrate_and_plant_proteins_of_unknown_...

description:
  This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant proteins of unknown ...


id: SM01194
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01194
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01194_The_release_factor_eRF1_terminates_protein_biosynthesis_by_recognising_stop_codons_at_the_A_site_of_the_ribosome_and_stimulating_peptidyl-tRNA_bond_hydrolysis_at_the_peptidyl_transferase_centre._The_crystal_structure_of_human_eRF1_is_known_...

description:
  The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known ...


id: SM01199
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01199
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01199_The_FDF_domain,_so_called_because_of_the_conserved_FDF_at_its_N_termini,_is_an_entirely_alpha-helical_domain_with_multiple_exposed_hydrophilic_loops._It_is_found_at_the_C_terminus_of_Scd6p-like_SM_domains._It_is_also_found_with_other_divergent_Sm_...

description:
  The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C terminus of Scd6p-like SM domains. It is also found with other divergent Sm ...


id: SM01203
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01203
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01203_This_domain_is_found_in_eukaryotes._This_domain_is_typically_between_135_and_149_amino_acids_in_length_and_is_found_associated_with_the_CH_domain.

description:
  This domain is found in eukaryotes. This domain is typically between 135 and 149 amino acids in length and is found associated with the CH domain.


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01241
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01241
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01241_Integrins_are_a_group_of_transmembrane_proteins_which_function_as_extracellular_matrix_receptors_and_in_cell_adhesion._Integrins_are_ubiquitously_expressed_and_are_heterodimeric,_each_composed_of_an_alpha_and_beta_subunit._Several_variations_of_the_...

description:
  Integrins are a group of transmembrane proteins which function as extracellular matrix receptors and in cell adhesion. Integrins are ubiquitously expressed and are heterodimeric, each composed of an alpha and beta subunit. Several variations of the ...


id: SM01242
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01242
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01242_This_is_the_beta_tail_domain_of_the_Integrin_protein._Integrins_are_receptors_which_are_involved_in_cell-cell_and_cell-extracellular_matrix_interactions.

description:
  This is the beta tail domain of the Integrin protein. Integrins are receptors which are involved in cell-cell and cell-extracellular matrix interactions.


id: SM01253
description: Domain of Kin17 curved DNA-binding protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01253
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01253_Domain_of_Kin17_curved_DNA-binding_protein


id: SM01254
description: Predicted coiled-coil domain-containing protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01254
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01254_Predicted_coiled-coil_domain-containing_protein


id: SM01257
description: Ki-ras-induced actin-interacting protein-IP3R-interacting domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01257
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01257_Ki-ras-induced_actin-interacting_protein-IP3R-interacting_domain


id: SM01262
description: Late endosomal/lysosomal adaptor and MAPK and MTOR activator
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01262
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01262_Late_endosomal/lysosomal_adaptor_and_MAPK_and_MTOR_activator


id: SM01265
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01265
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01265_This_family_contains_Mab-21_and_Mab-21_like_proteins._In_C._elegans_these_proteins_are_required_for_several_aspects_of_embryonic_development_PUBMED:8582275

description:
  This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development PUBMED:8582275


id: SM01272
description: This domain is found associated with Lsm domain PMID:16115810.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01272
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01272_This_domain_is_found_associated_with_Lsm_domain_PMID:16115810.


id: SM01278
description: Mitogen-activated protein kinase kinase 1 interacting
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01278
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01278_Mitogen-activated_protein_kinase_kinase_1_interacting


id: SM01281
description: Transcription mediator complex subunit Med12
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01281
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01281_Transcription_mediator_complex_subunit_Med12


id: SM01285
description: FACT complex subunit SPT16 N-terminal lobe domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01285
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01285_FACT_complex_subunit_SPT16_N-terminal_lobe_domain


id: SM01296
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01296
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01296_This_family_features_sequences_that_are_similar_to_a_region_of_hypothetical_yeast_gene_product_N2227._This_is_thought_to_be_expressed_during_meiosis_and_may_be_involved_in_the_defence_response_to_stressful_conditions_PMID:8771715.

description:
  This family features sequences that are similar to a region of hypothetical yeast gene product N2227. This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions PMID:8771715.


id: SM01300
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01300
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01300_This_domain_was_first_identified_in_drosophila_MSL1_(male-specific_lethal_1)_PMID:12698291._In_drosophila_it_binds_to_the_histone_acetyltransferase_males-absent_on_the_first_protein_(MOF)_and_to_protein_male-specific_lethal-3_(MSL3)_PMID:15141166

description:
  This domain was first identified in drosophila MSL1 (male-specific lethal 1) PMID:12698291. In drosophila it binds to the histone acetyltransferase males-absent on the first protein (MOF) and to protein male-specific lethal-3 (MSL3) PMID:15141166


id: SM01313
description: Exocyst complex component SEC3 N-terminal PIP2 binding PH
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01313
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01313_Exocyst_complex_component_SEC3_N-terminal_PIP2_binding_PH


id: SM01318
description: Single domain von Willebrand factor type C
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01318
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01318_Single_domain_von_Willebrand_factor_type_C


id: SM01326
description: C2 domain of PTEN tumour-suppressor protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01326
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01326_C2_domain_of_PTEN_tumour-suppressor_protein


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01330
description: Frizzled/Smoothened family membrane region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01330
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01330_Frizzled/Smoothened_family_membrane_region


id: SM01332
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01332
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01332_Cyclins_are_a_family_of_proteins_that_control_the_progression_of_cells_through_the_cell_cycle_by_activating_cyclin-dependent_kinase_(Cdk)_enzymes.

description:
  Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.


id: SM01335
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01335
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01335_This_domain_is_found_in_poly(ADP-ribose)-synthetases_(PMID:15112237)._The_function_of_this_domain_is_unknown.

description:
  This domain is found in poly(ADP-ribose)-synthetases (PMID:15112237). The function of this domain is unknown.


id: SM01336
description: Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01336
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01336_Poly(ADP-ribose)_polymerase_and_DNA-Ligase_Zn-finger_region


id: SM01337
description: Anaphase-promoting complex, subunit 10 (APC10)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01337
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01337_Anaphase-promoting_complex,_subunit_10_(APC10)


id: SM01338
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01338
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01338_NOTCH_signalling_plays_a_fundamental_role_during_a_great_number_of_developmental_processes_in_multicellular_animals_(PMID:10221902,_11112321)._NOD_and_NODP_represent_a_region_present_in_many_NOTCH_proteins_and_NOTCH_homologs_in_multiple_species_such_...

description:
  NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals (PMID:10221902, 11112321). NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such ...


id: SM01339
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01339
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01339_NOTCH_signalling_plays_a_fundamental_role_during_a_great_number_of_developmental_processes_in_multicellular_animals_(PMID:10221902,_11112321)._NOD_and_NODP_represent_a_region_present_in_many_NOTCH_proteins_and_NOTCH_homologs_in_multiple_species_such_...

description:
  NOTCH signalling plays a fundamental role during a great number of developmental processes in multicellular animals (PMID:10221902, 11112321). NOD and NODP represent a region present in many NOTCH proteins and NOTCH homologs in multiple species such ...


id: SM01343
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01343
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01343_The_FATC_domain_is_named_after_FRAP,_ATM,_TRRAP_C-terminal_(PMID:10782091)._The_solution_structure_of_the_FATC_domain_suggests_it_plays_a_role_in_redox-dependent_structural_and_cellular_stability_(PMID:15772072).

description:
  The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072).


id: SM01349
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01349
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01349_XMAP215/Dis1_proteins,_such_as_Alp14_and_XMAP215,_increase_microtubules_dynamic_polymerization_rates_by_recruiting_soluble_αβ-tubulin_via_their_conserved_TOG_domains_to_polymerizing_microtubule_plus_ends.

description:
  XMAP215/Dis1 proteins, such as Alp14 and XMAP215, increase microtubules dynamic polymerization rates by recruiting soluble αβ-tubulin via their conserved TOG domains to polymerizing microtubule plus ends.


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01353
description: Apoptosis-inducing factor, mitochondrion-associated, C-term
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01353
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01353_Apoptosis-inducing_factor,_mitochondrion-associated,_C-term


id: SM01355
description: Clathrin-adaptor complex-3 beta-1 subunit C-terminal
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01355
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01355_Clathrin-adaptor_complex-3_beta-1_subunit_C-terminal


id: SM01368
description: Retinoblastoma-associated protein A domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01368
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01368_Retinoblastoma-associated_protein_A_domain


id: SM01371
description: Transcription factor IIA, alpha/beta subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01371
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01371_Transcription_factor_IIA,_alpha/beta_subunit


id: SM01372
description: E2F/DP family winged-helix DNA-binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01372
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01372_E2F/DP_family_winged-helix_DNA-binding_domain


id: SM01378
description: Reactive mitochondrial oxygen species modulator 1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01378
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01378_Reactive_mitochondrial_oxygen_species_modulator_1


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01385
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01385
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01385_This_family_contains_the_breast_cancer_tumour_suppressor_BRCA2-interacting_protein_DSS1_and_its_homologue_SEM1,_both_of_which_are_short_acidic_proteins._DSS1_has_been_shown_to_be_a_conserved_component_of_the_Rae1_mediated_mRNA_export_pathway_in_...

description:
  This family contains the breast cancer tumour suppressor BRCA2-interacting protein DSS1 and its homologue SEM1, both of which are short acidic proteins. DSS1 has been shown to be a conserved component of the Rae1 mediated mRNA export pathway in ...


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01393
description: This family includes ribosomal protein L32 from eukaryotes and archaebacteria.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01393
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01393_This_family_includes_ribosomal_protein_L32_from_eukaryotes_and_archaebacteria.


id: SM01395
description: Transcription factor TFIIH complex subunit Tfb5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01395
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01395_Transcription_factor_TFIIH_complex_subunit_Tfb5


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01406
description: Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01406
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01406_Family_of_proteins_with_a_conserved_region_found_in_PAPA-1,_a_PAP-1_binding_protein.


id: SM01408
description: Inhibitor of growth proteins N-terminal histone-binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01408
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01408_Inhibitor_of_growth_proteins_N-terminal_histone-binding


id: SM01419
description: Alpha-macro-globulin thiol-ester bond-forming region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01419
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01419_Alpha-macro-globulin_thiol-ester_bond-forming_region


id: SM01477
description: DDE transposase retroviral integrase sub-family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01477
name:
  Protein Domains (SMART).STRING_v12.0_224129_STRINGid_SM01477_DDE_transposase_retroviral_integrase_sub-family


