# geneInfo

ensembl_gene_id: BSU00010
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression as well as that of other genes.


ensembl_gene_id: BSU00020
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...]


ensembl_gene_id: BSU00040
symbol: recF
gene_biotype: protein_coding
description:
  DNA repair and genetic recombination factor; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Is recruited to repair centers, foci that are the site of double- strand DNA break(s) after RecN and RecO; recruitment may depend on RecO.


ensembl_gene_id: BSU00050
symbol: yaaB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Regulates the biosynthesis of the extracellular matrix and the biofilm formation. May act as an enhancer of biofilm gene expression. Acts in parallel to the pathway that governs SinR derepression.


ensembl_gene_id: BSU00060
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase (subunit B); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: BSU00070
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase (subunit A); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: BSU00080
symbol: yaaC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.


ensembl_gene_id: BSU00090
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.


ensembl_gene_id: BSU00100
symbol: dacA
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Belongs to the peptidase S11 family.


ensembl_gene_id: BSU00110
symbol: pdxS
gene_biotype: protein_coding
description:
  Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.


ensembl_gene_id: BSU00120
symbol: pdxT
gene_biotype: protein_coding
description:
  Glutamine amidotransferase for pyridoxal phosphate synthesis; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: BSU00130
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: BSU00140
symbol: dck
gene_biotype: protein_coding
description:
  Deoxyadenosine/deoxycytidine kinase; Plays an essential role in generating the deoxyribonucleotide precursors dATP AND dCTP for DNA metabolism. The phosphate acceptor specificity is strict toward deoxyadenosine (dAdo) and deoxycytidine (dCyd). The specificity toward the sugar moiety of the nucleoside is less strict. Both 2-deoxyribose, ribose, and arabinose nucleosides are phosphorylated, although the 2-deoxyribonucleosides are preferred. The phosphate donor specificity is dependent on the deoxyribonucleoside substrate, but GTP is efficient with both deoxycytidine and deoxyadenosine. O [...]


ensembl_gene_id: BSU00150
symbol: dgk
gene_biotype: protein_coding
description:
  Deoxyguanosine kinase; Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as phosphate donor than CTP, ATP and GTP.


ensembl_gene_id: BSU00160
symbol: yaaH
gene_biotype: protein_coding
description:
  Spore peptidoglycan hydrolase; N-acetylglucosaminidase involved in cortex peptidoglycan degradation during germination. Cleaves only partially degraded spore peptidoglycans. Recognizes muramic acid delta-lactam residues specific to spore peptidoglycans.


ensembl_gene_id: BSU00170
symbol: yaaI
gene_biotype: protein_coding
description:
  Putative isochorismatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the isochorismatase family.


ensembl_gene_id: BSU00180
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: BSU00190
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III (gamma and tau subunits); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.


ensembl_gene_id: BSU00200
symbol: yaaK
gene_biotype: protein_coding
description:
  DNA binding protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: BSU00210
symbol: recR
gene_biotype: protein_coding
description:
  DNA repair and recombination protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: BSU00230
symbol: bofA
gene_biotype: protein_coding
description:
  Inhibitor of the pro-sigma(K) processing machinery; Involved in the mediation of the intercompartmental coupling of pro-sigma K processing to events in the forespore. Inhibits SpoIVFB- processing activity until a signal has been received from the forespore. Could inhibit SpoIVFB metalloprotease activity by coordinating a zinc in the SpoIVFB active site, preventing access of a water molecule and the sequence of pro-sigma K, which are necessary for peptide bond hydrolysis to produce sigma-K.


ensembl_gene_id: BSU00240
symbol: csfB
gene_biotype: protein_coding
description:
  Forespore-specific anti-sigma factor; An anti-sigma-G factor, prevents premature activation of sigma-G factor in the forespore; overexpression leads to 1000-fold reduction in spore formation, spore formation stops after engulfment. Overexpression also inhibits sigma- G transcription activation activity. When both Gin and sigma-G are expressed in E.coli Gin inhibits sigma-G, strongly suggesting Gin inhibits by direct physical interaction.


ensembl_gene_id: BSU00250
symbol: xpaC
gene_biotype: protein_coding
description:
  Putative phosphatase; In double copy it causes aberrant cell morphology, filamentation and inhibits sporulation. Hydrolyzes 5-bromo-4- chloroindolyl phosphate.


ensembl_gene_id: BSU00260
symbol: yaaN
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12533473; Belongs to the TelA family.


ensembl_gene_id: BSU00270
symbol: yaaO
gene_biotype: protein_coding
description:
  Putative decarboxylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU00280
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: BSU00290
symbol: yaaQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds cyclic di-AMP (c-di-AMP) and is probably involved in c- di-AMP-mediated signaling pathways. In vitro, can also bind cyclic GMP- AMP (3'3'-cGAMP), with lower affinity, but not c-di-GMP or 2'3'-cGAMP.


ensembl_gene_id: BSU00310
symbol: holB
gene_biotype: protein_coding
description:
  DNA polymerase III delta' subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.


ensembl_gene_id: BSU00320
symbol: yaaT
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Essential for the phosphorelay during initiation of sporulation. May control the level of phosphorylated spo0A through spo0E activity during sporulation.


ensembl_gene_id: BSU00340
symbol: yabB
gene_biotype: protein_coding
description:
  Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU00350
symbol: yazA
gene_biotype: protein_coding
description:
  Putative UvrC-Intron-type (URI) endonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF0213 family.


ensembl_gene_id: BSU00360
symbol: rsmI
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase I; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: BSU00370
symbol: abrB
gene_biotype: protein_coding
description:
  Transcriptional regulator for transition state genes; Ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. It controls the expression of genes spovG and tycA. AbrB binds to the tycA promoter region at two A- and T-rich sites, it may be the sole repressor of tycA transcription; To B.subtilis Abh and SpoVT.


ensembl_gene_id: BSU00380
symbol: metS
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.


ensembl_gene_id: BSU00390
symbol: yabD
gene_biotype: protein_coding
description:
  Metal-dependent DNase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU00400
symbol: yabE
gene_biotype: protein_coding
description:
  Putative cell wall shaping enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU00410
symbol: rnmV
gene_biotype: protein_coding
description:
  Ribonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. Releases 5'-phosphoryl and 3'- hydroxy termini.


ensembl_gene_id: BSU00420
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine 16S ribosomal RNA transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.


ensembl_gene_id: BSU00430
symbol: yabG
gene_biotype: protein_coding
description:
  Sporulation-specific protease; Cleaves the spore coat proteins SpoIVA and SafA. May cooperate with tgl to mediate the temperature-dependent cross-linking of coat proteins like GerQ.


ensembl_gene_id: BSU00440
symbol: veg
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Stimulates biofilm formation via transcriptional activation of extracellular matrix genes. Acts by repressing SinR activity, independently of the SinI, SlrA and SlrR pathways. Could also be involved in the regulation of other genes during biofilm and spore formation.


ensembl_gene_id: BSU00450
symbol: sspF
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein (alpha/beta-type SASP); May play some important role in either sporulation or the dormant spore.


ensembl_gene_id: BSU00460
symbol: ispE
gene_biotype: protein_coding
description:
  4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: BSU00470
symbol: purR
gene_biotype: protein_coding
description:
  Transcriptional regulator of the purine biosynthesis operon; Controls the transcription of the pur operon for purine biosynthetic genes, binds to the control region of the operon. DNA binding is inhibited by 5-phosphoribosyl 1-pyrophosphate; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: BSU00480
symbol: yabJ
gene_biotype: protein_coding
description:
  Aminoacrylate/iminopropionate hydrolase/deaminase; Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydratase (IlvA) in the low water environment of the cell. It catalyzes the deamination of enamine/imine intermediates to yield 2-ketobutyrate and ammonia. It is required for the detoxification of reactive intermediates of IlvA due to their highly nucleophilic abilities. Involved in the isoleucine biosynthesis. May have a role in the purine metabolism; Belongs to the RutC family.


ensembl_gene_id: BSU00490
symbol: spoVG
gene_biotype: protein_coding
description:
  Regulator required for spore cortex synthesis (stage V sporulation); Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation. Belongs to the SpoVG family.


ensembl_gene_id: BSU00500
symbol: gcaD
gene_biotype: protein_coding
description:
  Bifunctional glucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belon [...]


ensembl_gene_id: BSU00510
symbol: prs
gene_biotype: protein_coding
description:
  Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).


ensembl_gene_id: BSU00520
symbol: ctc
gene_biotype: protein_coding
description:
  Ribosomal protein Ctc, binding 5S RNA; Not required for exponential growth; probably functions in vegetatively growing cells, maybe required for accurate translation under stress conditions.


ensembl_gene_id: BSU00530
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: BSU00540
symbol: fin
gene_biotype: protein_coding
description:
  Protein required for the switch from F to G during sporulation (anti sigma F); An anti-sigma factor for sporulation specific sigma-F factor, by antagonizing sigma-F it allows the switch to sigma-G factor and progression to the late sporulation development stages. Might stabilize or process Holliday junction intermediates, although this may be due to polar effects on the downstream mfd gene.


ensembl_gene_id: BSU00550
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the N-terminal section; belongs to the UvrB family.


ensembl_gene_id: BSU00560
symbol: spoVT
gene_biotype: protein_coding
description:
  Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh.


ensembl_gene_id: BSU00570
symbol: yabM
gene_biotype: protein_coding
description:
  Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU00580
symbol: yabN
gene_biotype: protein_coding
description:
  Putative fusion methylase and nucleotide pyrophosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU00590
symbol: hslR
gene_biotype: protein_coding
description:
  Ribosomal RNA binding protein involved in 50S recycling; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: BSU00610
symbol: yabQ
gene_biotype: protein_coding
description:
  Membrane protein of the forespore; Required for sporulation. Plays an important role in cortex and coat formation.


ensembl_gene_id: BSU00620
symbol: divIC
gene_biotype: protein_coding
description:
  Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E.


ensembl_gene_id: BSU00630
symbol: yabR
gene_biotype: protein_coding
description:
  Putative RNA degradation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase U57 family.


ensembl_gene_id: BSU00640
symbol: spoIIE
gene_biotype: protein_coding
description:
  SpoIIAA-phosphate serine phosphatase; Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation.


ensembl_gene_id: BSU00660
symbol: yabT
gene_biotype: protein_coding
description:
  Putative serine/threonine-protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU00670
symbol: tilS
gene_biotype: protein_coding
description:
  tRNAile lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: BSU00680
symbol: hprT
gene_biotype: protein_coding
description:
  Hypoxanthine-guanine phosphoribosyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU00690
symbol: ftsH
gene_biotype: protein_coding
description:
  Cell-division protein and general stress protein (class III heat-shock); Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: BSU00700
symbol: coaX
gene_biotype: protein_coding
description:
  Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. Cannot utilize a phosphoryl donor other than ATP; Belongs to the type III pantothenate kinase family.


ensembl_gene_id: BSU00710
symbol: hslO
gene_biotype: protein_coding
description:
  Disulfide bond chaperone (heat shock protein HSP33); Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: BSU00720
symbol: yacD
gene_biotype: protein_coding
description:
  Putative protein secretion PrsA homolog; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU00730
symbol: cysK
gene_biotype: protein_coding
description:
  Cysteine synthase; Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present, the pool of O-acetylserine (OAS) is low, which leads to the formation of a CymR- CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine, the OAS pool is high and the CymR-CysK complex is mostly dissociated, leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression.


ensembl_gene_id: BSU00740
symbol: pabB
gene_biotype: protein_coding
description:
  4-amino-4-deoxychorismate synthase (para-aminobenzoate synthase); Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC.


ensembl_gene_id: BSU00750
symbol: pabA
gene_biotype: protein_coding
description:
  4-amino-4-deoxychorismate synthase; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC. PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB. Also involved in the biosynthesis of anthranilate.


ensembl_gene_id: BSU00760
symbol: pabC
gene_biotype: protein_coding
description:
  4-amino-4-deoxychorismate pyruvate-lyase; Involved in the biosynthesis of p-aminobenzoate (PABA), a precursor of tetrahydrofolate. Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate (By similarity).


ensembl_gene_id: BSU00770
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. Belongs to the DHPS family.


ensembl_gene_id: BSU00780
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: BSU00790
symbol: folK
gene_biotype: protein_coding
description:
  7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the HPPK family.


ensembl_gene_id: BSU00800
symbol: yazB
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU00810
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family.


ensembl_gene_id: BSU00820
symbol: lysS
gene_biotype: protein_coding
description:
  lysyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: BSU00830
symbol: ctsR
gene_biotype: protein_coding
description:
  Transcriptional regulator; Controls the expression of the cellular protein quality control genes clpC, clpE and clpP, as well as mcsA and mcsB. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock, CtsR is degraded by the ClpCP and ClpEP proteolytic systems, ensuring the derepression of clpE, clpP and the clpC operon. CtsR negatively autoregulates its own synthesis.


ensembl_gene_id: BSU00840
symbol: mcsA
gene_biotype: protein_coding
description:
  Activator of protein kinase McsB; Activates the phosphorylation activity of the protein- arginine kinase McsB. Is required for the delocalization of competence proteins from the cell poles.


ensembl_gene_id: BSU00850
symbol: mcsB
gene_biotype: protein_coding
description:
  Protein tyrosine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system, where it is involved in regulating the global heat shock repressor CtsR; phosphorylates arginine residues in the winged helix- turn-helix domain of CtsR, thereby preventing its binding to DNA and consequently inducing the expression of repressed genes. The transcriptional repressor HrcA, the chaperone GroEL, the unfoldase ClpC, together with several ribosomal subunits, represent other physiological targets of McsB under str [...]


ensembl_gene_id: BSU00860
symbol: clpC
gene_biotype: protein_coding
description:
  Class III stress response-related ATPase, AAA+ superfamily; Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK; Belongs to the ClpA/ClpB family. ClpC subfamily.


ensembl_gene_id: BSU00870
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: BSU00880
symbol: disA
gene_biotype: protein_coding
description:
  Diadenylate cyclase; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. Forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. Its ability to scan through the chromosome rapidly is due to its non-specific DNA- binding. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. It is required, at least partially, to inhibit the activity of the transcription factor spo0A, which controls, amo [...]


ensembl_gene_id: BSU00890
symbol: yacL
gene_biotype: protein_coding
description:
  Putative membrane protein; An RNase; In the central section; belongs to the PINc/VapC protein family.


ensembl_gene_id: BSU00900
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, nonmevalonate isoprenoid pathway; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: BSU00910
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP); Belongs to the IspF family.


ensembl_gene_id: BSU00920
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: BSU00930
symbol: cysE
gene_biotype: protein_coding
description:
  Serine acetyltransferase; Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS).


ensembl_gene_id: BSU00940
symbol: cysS
gene_biotype: protein_coding
description:
  cysteinyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: BSU00950
symbol: mrnC
gene_biotype: protein_coding
description:
  Ribonuclease for 23S RNA maturation; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors. Cleaves more efficiently on assembled 50S ribosomal subunits. Cleavage is strongly stimulated by ribosomal protein L3 (RplC); 20-30% DMSO can replace RplC, suggesting RplC may alter rRNA conformation.


ensembl_gene_id: BSU00960
symbol: rlmB
gene_biotype: protein_coding
description:
  23S rRNA methyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: BSU00970
symbol: yacP
gene_biotype: protein_coding
description:
  Putative ribonuclease with PIN and NYN domains; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU00980
symbol: sigH
gene_biotype: protein_coding
description:
  RNA polymerase sigma-30 factor (sigma(H)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in the transition to post- exponential phase in the beginning of sporulation. It is also required for transcription of several stationary phase genes.


ensembl_gene_id: BSU01000
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: BSU01010
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination factor; Participates in transcription elongation, termination and antitermination. Stimulates RNA polymerase pausing at U107 and U144 in the trp leader. NusG-stimulated pausing is sequence specific. Does not affect trp leader termination.


ensembl_gene_id: BSU01020
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11 (BL11); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.


ensembl_gene_id: BSU01030
symbol: rplA
gene_biotype: protein_coding
description:
  Ribosomal protein L1 (BL1); Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. Belongs to the universal ribosomal protein uL1 family.


ensembl_gene_id: BSU01040
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10 (BL5); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (such as IF-2, EF-Tu, EF-G and RF3).


ensembl_gene_id: BSU01050
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L12 (BL9); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.


ensembl_gene_id: BSU01060
symbol: ybxB
gene_biotype: protein_coding
description:
  Ribosomal RNA methyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the methyltransferase superfamily.


ensembl_gene_id: BSU01070
symbol: rpoB
gene_biotype: protein_coding
description:
  RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BSU01080
symbol: rpoC
gene_biotype: protein_coding
description:
  RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BSU01090
symbol: rplGB
gene_biotype: protein_coding
description:
  Alternative ribosomal protein L7A; RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs. Belongs to the eukaryotic ribosomal protein eL8 family.


ensembl_gene_id: BSU01110
symbol: rpsG
gene_biotype: protein_coding
description:
  Ribosomal protein S7 (BS7); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: BSU01120
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).


ensembl_gene_id: BSU01130
symbol: tufA
gene_biotype: protein_coding
description:
  Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: BSU01150
symbol: rpsJ
gene_biotype: protein_coding
description:
  Ribosomal protein S10 (BS13); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: BSU01160
symbol: rplC
gene_biotype: protein_coding
description:
  Ribosomal protein L3 (BL3); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity). Strongly stimulates 23S rRNA precursor processing by mini-ribonuclease 3 (MrnC); 20-30% DMSO can replace L3, suggesting the protein may alter rRNA conformation; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: BSU01170
symbol: rplD
gene_biotype: protein_coding
description:
  Ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.


ensembl_gene_id: BSU01180
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: BSU01190
symbol: rplB
gene_biotype: protein_coding
description:
  Ribosomal protein L2 (BL2); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: BSU01200
symbol: rpsS
gene_biotype: protein_coding
description:
  Ribosomal protein S19 (BS19); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: BSU01210
symbol: rplV
gene_biotype: protein_coding
description:
  Ribosomal protein L22 (BL17); This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).


ensembl_gene_id: BSU01220
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3 (BS3); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: BSU01230
symbol: rplP
gene_biotype: protein_coding
description:
  Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: BSU01240
symbol: rpmC
gene_biotype: protein_coding
description:
  Ribosomal protein L29; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.


ensembl_gene_id: BSU01250
symbol: rpsQ
gene_biotype: protein_coding
description:
  Ribosomal protein S17 (BS16); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: BSU01260
symbol: rplNA
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: BSU01270
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24 (BL23); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. Has also been isolated as a basic, heat-shock stable DNA- binding protein from the B.subtilis nucleoid. It binds cooperatively to double-stranded supercoiled DNA which it further compacts into complexes 15-17 nm in diameter. Overexpression of the protein disrupts nucleoid segregation and positioning.


ensembl_gene_id: BSU01280
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5 (BL6); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: BSU01290
symbol: rpsNA
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity). The major S14 protein in the ribosome. Required for binding of S2 and S3 to the 30S subunit and for association of the 30S with the 50S subunit; Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.


ensembl_gene_id: BSU01300
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8 (BS8); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: BSU01310
symbol: rplF
gene_biotype: protein_coding
description:
  Ribosomal protein L6 (BL8); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.


ensembl_gene_id: BSU01320
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: BSU01330
symbol: rpsE
gene_biotype: protein_coding
description:
  Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations); Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: BSU01340
symbol: rpmD
gene_biotype: protein_coding
description:
  Ribosomal protein L30 (BL27); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure.


ensembl_gene_id: BSU01350
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: BSU01360
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: BSU01370
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: BSU01380
symbol: mapA
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.


ensembl_gene_id: BSU01389
symbol: ybzG
gene_biotype: protein_coding
description:
  Putative ribosomal protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU01390
symbol: infA
gene_biotype: protein_coding
description:
  Initiation factor IF-I; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: BSU01400
symbol: rpmJ
gene_biotype: protein_coding
description:
  Ribosomal protein L36 (ribosomal protein B); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.


ensembl_gene_id: BSU01410
symbol: rpsM
gene_biotype: protein_coding
description:
  Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: BSU01420
symbol: rpsK
gene_biotype: protein_coding
description:
  Ribosomal protein S11 (BS11); Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: BSU01430
symbol: rpoA
gene_biotype: protein_coding
description:
  RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: BSU01440
symbol: rplQ
gene_biotype: protein_coding
description:
  Ribosomal protein L17 (BL15); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.


ensembl_gene_id: BSU01450
symbol: ecfA
gene_biotype: protein_coding
description:
  Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.


ensembl_gene_id: BSU01470
symbol: ecfT
gene_biotype: protein_coding
description:
  Component of the influx ECF transporters; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity). Involved in riboflavin transport.


ensembl_gene_id: BSU01480
symbol: truA
gene_biotype: protein_coding
description:
  Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: BSU01490
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: BSU01500
symbol: rpsI
gene_biotype: protein_coding
description:
  Ribosomal protein S9; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure.


ensembl_gene_id: BSU01510
symbol: ybaJ
gene_biotype: protein_coding
description:
  Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the methyltransferase superfamily.


ensembl_gene_id: BSU01520
symbol: ybaK
gene_biotype: protein_coding
description:
  Putative alkylated deoxynucleotide triphosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU01530
symbol: cwlD
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; Cleaves the peptide side chain from the N-acetylmuramic acid residues in peptidoglycan. This is a step in the formation of muramic delta-lactam residues in spore cortex.


ensembl_gene_id: BSU01540
symbol: salA
gene_biotype: protein_coding
description:
  Mrp family regulator; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: BSU01550
symbol: gerD
gene_biotype: protein_coding
description:
  Lipoprotein with a role in spores' rapid response to nutrient germinants; May be involved in fructose recognition during germination.


ensembl_gene_id: BSU01560
symbol: kbaA
gene_biotype: protein_coding
description:
  Inner membrane protein involved in activation of the KinB signaling pathway to sporulation; Involved in the activation of the KinB signaling pathway of sporulation.


ensembl_gene_id: BSU01570
symbol: ybaN
gene_biotype: protein_coding
description:
  Polysaccharide deacetylase involved in sporulation; Necessary to maintain spores after the late stage of sporulation. Might be involved in cortex formation.


ensembl_gene_id: BSU01580
symbol: ybaR
gene_biotype: protein_coding
description:
  Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m: membrane component.


ensembl_gene_id: BSU01590
symbol: ybaS
gene_biotype: protein_coding
description:
  Putative sodium dependent transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU01600
symbol: ybbA
gene_biotype: protein_coding
description:
  Putative iron-chelator esterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU01610
symbol: feuC
gene_biotype: protein_coding
description:
  Iron-uptake protein; Involved in the uptake of iron. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU01630
symbol: feuA
gene_biotype: protein_coding
description:
  Iron hydroxamate-binding lipoprotein; Involved in the uptake of iron. Belongs to the bacterial solute-binding protein 8 family.


ensembl_gene_id: BSU01640
symbol: btr
gene_biotype: protein_coding
description:
  HTH-type transcriptional activator Btr; In iron-limited conditions, activates expression of the feuABCybbA operon, which encodes the bacillibactin uptake system. Acts by binding directly to a conserved direct repeat element upstream of the feuA promoter. Activity is increased in the presence of bacillibactin.


ensembl_gene_id: BSU01660
symbol: nagZ
gene_biotype: protein_coding
description:
  N-acetylglucosaminidase lipoprotein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Cleaves muropeptides, but not peptidoglycan. Belongs to the glycosyl hydrolase 3 family.


ensembl_gene_id: BSU01670
symbol: amiE
gene_biotype: protein_coding
description:
  Amidase hydrolyzing N-acetylmuramyl-L-Ala bond of MurNAc peptides; Involved in muropeptide recycling. Hydrolyzes the amide bond between N-acetylmuramic acid (MurNAc) and the L-alanine residue of the stem peptide. Cannot hydrolyze muropeptides containing N- acetylglucosamine (GlcNAc) at the non-reducing end.


ensembl_gene_id: BSU01680
symbol: ybbF
gene_biotype: protein_coding
description:
  Putative PTS system EIIBC component ybbF; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.


ensembl_gene_id: BSU01700
symbol: murQ
gene_biotype: protein_coding
description:
  D-lactyl ether N-acetylmuramic-6-phosphate acid etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.


ensembl_gene_id: BSU01710
symbol: ybbJ
gene_biotype: protein_coding
description:
  Putative acyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU01730
symbol: sigW
gene_biotype: protein_coding
description:
  RNA polymerase ECF(extracytoplasmic function)-type sigma factor W; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in response to cell envelope stress such as antimicrobial peptides , alkaline pH , transport processes and detoxification.


ensembl_gene_id: BSU01740
symbol: rsiW
gene_biotype: protein_coding
description:
  anti-sigma(W) factor; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-W (SigW). Holds SigW, its cognate ECF sigma factor, in an inactive form until released by regulated intramembrane proteolysis (RIP). SigW and RsiW mediate cell response to cell wall stress. RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, PrsW) , then within the membrane itself (site-2 protease, S2P [...]


ensembl_gene_id: BSU01750
symbol: ybbP
gene_biotype: protein_coding
description:
  Putative enzyme with DAC domain protein; One of 3 paralogous diadenylate cyclases (DAC) in this bacteria, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP) (Probable). Upon expression in E.coli leads to c-di- AMP synthesis. Probably the main producer of c-di-AMP for the cell; is probably implicated in control of peptidogylcan synthesis. In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.


ensembl_gene_id: BSU01760
symbol: ybbR
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Upon coexpression in E.coli stimulates the diadenylate cyclase activity of CdaA about 20-fold. In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.


ensembl_gene_id: BSU01770
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity). Glucosamine-1-phosphate is used for cell wall biosynthesis (Probable); Belongs to the phosphohexose mutase family.


ensembl_gene_id: BSU01780
symbol: glmS
gene_biotype: protein_coding
description:
  L-glutamine-D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: BSU01800
symbol: alkA
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase; Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Catalyzes the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine and 7- methylguanine from the damaged DNA polymer formed by alkylation lesions.


ensembl_gene_id: BSU01810
symbol: adaA
gene_biotype: protein_coding
description:
  methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC/XylS family); Is involved in the adaptive response to alkylation damage in DNA caused by alkylating agents. Repairs the methylphosphotriester lesions in DNA by a direct and irreversible transfer of the methyl group to one of its own cysteine residues.


ensembl_gene_id: BSU01820
symbol: adaB
gene_biotype: protein_coding
description:
  O6-methylguanine-DNA methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: BSU01830
symbol: ndhF
gene_biotype: protein_coding
description:
  Putative NADH dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the complex I subunit 5 family.


ensembl_gene_id: BSU01845
symbol: ybcC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0753 family.


ensembl_gene_id: BSU01860
symbol: ybcF
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: BSU01889
symbol: ybzH
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (ArsR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU01890
symbol: ybcL
gene_biotype: protein_coding
description:
  Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU01900
symbol: ybcM
gene_biotype: protein_coding
description:
  Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU01910
symbol: skfA
gene_biotype: protein_coding
description:
  Sporulation killing factor A; Produces a 26-residue extracellular sporulation filling factor (SKF) that induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, providing a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation. Can also inhibit growth of other bacteria at high concentrations. Addition of SKF to solid cultures induces killing, but it is much less effective than SDP (AC O34344). Has a role in protecting the secreted lipase LipA against pro [...]


ensembl_gene_id: BSU01920
symbol: skfB
gene_biotype: protein_coding
description:
  Synthesis of sporulation killing factor A; Catalyzes the formation of the thioether bond required for production of the sporulation killing factor (SKF) from SkfA. Forms the cysteine-methionine thioether bond found in SKF; the acceptor amino acid can be hydrophobic, aromatic or a small hydrophilic amino acid but not a larger hydrophilic amino acid, i.e. Met=Ala, Phe, Leu, Tyr>Asn, Ser>>Gln, Glu, Lys. The relative position of Cys and Met in the substrate cannot be inverted, in vitro the thioether bond cannot be made in the absence of the SkfA propeptide, suggesting this is the first rea [...]


ensembl_gene_id: BSU01935
symbol: skfC
gene_biotype: protein_coding
description:
  Sporulation killing factor biosynthesis and export; Required for production of the bacteriocin SkfA.


ensembl_gene_id: BSU01950
symbol: skfE
gene_biotype: protein_coding
description:
  Sporulation killing factor biosynthesis and export; Probably part of the ABC transporter SkfEF involved in the export of the bacteriocin SKF. Probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU01960
symbol: skfF
gene_biotype: protein_coding
description:
  Sporulation killing factor biosynthesis and export; Probably part of the ABC transporter SkfEF involved in the export of the bacteriocin SKF. Probably responsible for the translocation of bacteriocin SkfA across the membrane.


ensembl_gene_id: BSU01990
symbol: ybdG
gene_biotype: protein_coding
description:
  Putative hydrolase/transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU02010
symbol: ybdK
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YbdJ]; Member of the two-component regulatory system YbdK/YbdJ. Probably activates YbdJ by phosphorylation.


ensembl_gene_id: BSU02030
symbol: ybdM
gene_biotype: protein_coding
description:
  Putative protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU02040
symbol: ybdN
gene_biotype: protein_coding
description:
  Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: BSU02060
symbol: ybxG
gene_biotype: protein_coding
description:
  Putative amino acid permease; Probable amino-acid or metabolite transport protein; Belongs to the amino acid-polyamine-organocation (APC) superfamily.


ensembl_gene_id: BSU02070
symbol: csgA
gene_biotype: protein_coding
description:
  Sporulation-specific SASP protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU02090
symbol: ybxI
gene_biotype: protein_coding
description:
  Exported beta-lactamase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU02100
symbol: cypC
gene_biotype: protein_coding
description:
  Fatty acid beta-hydroxylating cytochrome P450; Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide; Belongs to the cytochrome P450 family.


ensembl_gene_id: BSU02120
symbol: ybeC
gene_biotype: protein_coding
description:
  Putative H+/amino acid transporter; Uptake of an yet unknown amino-acid with the concomitant import of a proton; Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family.


ensembl_gene_id: BSU02130
symbol: glpQA
gene_biotype: protein_coding
description:
  Glycerophosphoryl diester phosphodiesterase; Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols.


ensembl_gene_id: BSU02140
symbol: glpT
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate permease; Responsible for glycerol-3-phosphate uptake; Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.


ensembl_gene_id: BSU02170
symbol: ybfB
gene_biotype: protein_coding
description:
  Putative carboxylate transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU02200
symbol: ybfG
gene_biotype: protein_coding
description:
  Putative pepdidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU02210
symbol: ybfH
gene_biotype: protein_coding
description:
  Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU02220
symbol: ybfI
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (AraC/XylS family, cupin family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU02230
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Catalyzes two reactions: the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR; the second, a side reaction, is the production of acetyl phosphate and ADP from acetate and ATP.


ensembl_gene_id: BSU02240
symbol: mpr
gene_biotype: protein_coding
description:
  Extracellular glutamyl-endopeptidase; Evidence 1c: Function experimentally demonstrated in the studied genus; Product type e: enzyme; Belongs to the peptidase S1B family.


ensembl_gene_id: BSU02250
symbol: ybfJ
gene_biotype: protein_coding
description:
  Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.


ensembl_gene_id: BSU02270
symbol: pssA
gene_biotype: protein_coding
description:
  Phosphatidylserine synthase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: BSU02280
symbol: ybfM
gene_biotype: protein_coding
description:
  Putative membrane phosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU02290
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.


ensembl_gene_id: BSU02310
symbol: ybfO
gene_biotype: protein_coding
description:
  Putative exported hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU02330
symbol: ybfQ
gene_biotype: protein_coding
description:
  Putative enzyme with rhodanese domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF0176 family.


ensembl_gene_id: BSU02340
symbol: gltP
gene_biotype: protein_coding
description:
  Proton/glutamate symport protein; Catalyzes the proton-dependent, binding-protein-independent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BSU02350
symbol: gamP
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) glucosamine-specific enzyme IICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system may be involved in glucosamine transport.


ensembl_gene_id: BSU02360
symbol: nagBB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.


ensembl_gene_id: BSU02370
symbol: ybgA
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (GntR family); Transcriptional repressor of genes involved in glucosamine transport and utilization. Represses the expression of the gamAP operon by binding to the gamA-gamR intergenic region.


ensembl_gene_id: BSU02380
symbol: ybgB
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 12897008.


ensembl_gene_id: BSU02390
symbol: ilvE
gene_biotype: protein_coding
description:
  Ketomethiobutyrate-branched-chain/aromatic amino acid aminotransferase; Transaminates branched-chain amino acids and ketoglutarate. Involved in the final step of the methionine regeneration pathway, where ketomethiobutyrate (KMTB) is converted to methionine via a transamination. The amino donor preference is isoleucine, leucine, valine, phenylalanine, and tyrosine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU02400
symbol: ybgF
gene_biotype: protein_coding
description:
  Putative aminoacid permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU02410
symbol: ybgG
gene_biotype: protein_coding
description:
  Homocysteine methylase using (R,S)AdoMet; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU02420
symbol: glnT
gene_biotype: protein_coding
description:
  Glutamine transporter; Probably functions as a sodium/glutamine symporter for glutamine uptake; Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.


ensembl_gene_id: BSU02430
symbol: glsA
gene_biotype: protein_coding
description:
  Glutaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU02440
symbol: glnJ
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [GlnL] for glutamine degradation; Member of the two-component regulatory system GlnK/GlnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. It seems that autophosphorylated GlnK transfers a phosphoryl group to GlnL, which positively regulates the expression of the glsA-glnT operon. Interaction between GlnK-AmtB complex and TnrA protects TnrA from proteolytic degradation.


ensembl_gene_id: BSU02450
symbol: glnL
gene_biotype: protein_coding
description:
  Two-component response regulator [GlnJ] for glutamine utilisation; Member of the two-component regulatory system GlnL/GlnK that positively regulates the expression of the glsA-glnT operon in response to glutamine. GlnL binds the promoter region of glsA-glnT in vitro.


ensembl_gene_id: BSU02460
symbol: ycbC
gene_biotype: protein_coding
description:
  5-dehydro-4-deoxyglucarate dehydratase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the DapA family.


ensembl_gene_id: BSU02470
symbol: ycbD
gene_biotype: protein_coding
description:
  2,5-dioxovalerate dehydrogenase (alpha-ketoglutaric semialdehyde dehydrogenase); Catalyzes the NAD(P)(+)-dependent oxidation of alpha- ketoglutaric semialdehyde (alphaKGSA) to alpha-ketoglutarate. Prefers NADP(+) to NAD(+) as a cosubstrate. In vitro, can also use various aldehydes.


ensembl_gene_id: BSU02480
symbol: gudP
gene_biotype: protein_coding
description:
  Glucarate transporter; Uptake of D-glucarate; Belongs to the major facilitator superfamily. Phthalate permease family.


ensembl_gene_id: BSU02490
symbol: gudD
gene_biotype: protein_coding
description:
  Glucarate dehydratase; Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D- glucarate (5-kdGluc); Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.


ensembl_gene_id: BSU02500
symbol: ycbG
gene_biotype: protein_coding
description:
  Transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU02510
symbol: garD
gene_biotype: protein_coding
description:
  D-galactarate dehydratase; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.


ensembl_gene_id: BSU02520
symbol: ycbJ
gene_biotype: protein_coding
description:
  Putative phosphotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aminoglycoside phosphotransferase family.


ensembl_gene_id: BSU02530
symbol: rtpA
gene_biotype: protein_coding
description:
  anti-TRAP regulator; By forming a complex with tryptophan-activated TRAP, and masking its RNA binding site, it inhibits TRAP's RNA binding ability, thereby abolishing TRAP regulation of gene expression, leading to antitermination and increased trp operon expression. AT acts by competing with messenger RNA for the RNA binding domain of TRAP.


ensembl_gene_id: BSU02540
symbol: ycbK
gene_biotype: protein_coding
description:
  Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: BSU02560
symbol: ycbM
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YcbL]; Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation.


ensembl_gene_id: BSU02570
symbol: ycbN
gene_biotype: protein_coding
description:
  Putative ABC efflux transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU02580
symbol: ycbO
gene_biotype: protein_coding
description:
  Putative Na+-driven exporter or maturation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU02590
symbol: ycbP
gene_biotype: protein_coding
description:
  Putative inner integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU02600
symbol: cwlJ
gene_biotype: protein_coding
description:
  Cell wall hydrolase; Probable spore cortex-lytic enzyme involved in the depolymerization of cortex peptidoglycan during germination.


ensembl_gene_id: BSU02620
symbol: phoD
gene_biotype: protein_coding
description:
  Alkaline phosphatase D; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: BSU02630
symbol: tatAD
gene_biotype: protein_coding
description:
  Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for PhoD secretion. The cytosolic fraction of TatAd binds the precursor of PhoD; Belongs to the TatA/E family.


ensembl_gene_id: BSU02640
symbol: tatCD
gene_biotype: protein_coding
description:
  Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Required for PhoD secretion. TatCd promotes membrane localization of TatAd via domain specific interactions. TatCd is required for stabile production of TatAd as well as for its maintenance; Belongs to the TatC family.


ensembl_gene_id: BSU02650
symbol: pcp
gene_biotype: protein_coding
description:
  Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.


ensembl_gene_id: BSU02660
symbol: ycbU
gene_biotype: protein_coding
description:
  Putative cysteine desulfurase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU02670
symbol: lmrB
gene_biotype: protein_coding
description:
  Efflux transporter; Proton-dependent transporter. May mediate the efflux of lincomycin; Belongs to the major facilitator superfamily. EmrB family.


ensembl_gene_id: BSU02680
symbol: lmrA
gene_biotype: protein_coding
description:
  Transcriptional repressor of lmrAB and yxaGH operons; Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons.


ensembl_gene_id: BSU02690
symbol: ansZ
gene_biotype: protein_coding
description:
  L-asparaginase 2 (putative lipoprotein); Catalyzes the conversion of L-asparagine to L-aspartate and ammonium.


ensembl_gene_id: BSU02700
symbol: estA
gene_biotype: protein_coding
description:
  Secreted alkaliphilic lipase; Active toward p-nitrophenyl esters and triacylglycerides with a marked preference for esters with C8 acyl groups. Belongs to the AB hydrolase superfamily.


ensembl_gene_id: BSU02710
symbol: yczC
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU02730
symbol: natK
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [NatR]; Member of the two-component regulatory system NatK/NatR that positively regulates the expression of the natAB operon. Potentially phosphorylates NatR.


ensembl_gene_id: BSU02740
symbol: natR
gene_biotype: protein_coding
description:
  Two-component response regulator [NatK]; Member of the two-component regulatory system NatK/NatR that positively regulates the expression of the natAB operon. Acts by binding directly to the promoter of natAB.


ensembl_gene_id: BSU02750
symbol: natA
gene_biotype: protein_coding
description:
  Na+ ABC efflux transporter (ATP-binding protein); Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU02760
symbol: natB
gene_biotype: protein_coding
description:
  Na+ ABC efflux transporter (permease); Part of an ABC transporter that catalyzes ATP-dependent electrogenic sodium extrusion.


ensembl_gene_id: BSU02770
symbol: yccK
gene_biotype: protein_coding
description:
  Putative ion channel associated enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.


ensembl_gene_id: BSU02780
symbol: ycdA
gene_biotype: protein_coding
description:
  Lipoprotein involved in swarming behaviour; Evidence 1b: Function experimentally demonstrated in the studied species; Product type lp: lipoprotein.


ensembl_gene_id: BSU02790
symbol: ycdB
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis YcdC.


ensembl_gene_id: BSU02800
symbol: ycdC
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis YcdB.


ensembl_gene_id: BSU02810
symbol: cwlK
gene_biotype: protein_coding
description:
  Murein L,D:-endopeptidase; Cleaves the linkage of the L-alanine-D-glutamic acid of B.subtilis cell wall; Belongs to the peptidase M15C family.


ensembl_gene_id: BSU02820
symbol: rapJ
gene_biotype: protein_coding
description:
  Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU02830
symbol: ycdF
gene_biotype: protein_coding
description:
  Putative glucose 1-dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU02840
symbol: ycdG
gene_biotype: protein_coding
description:
  Putative oligo-carbohydrate hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU02850
symbol: znuA
gene_biotype: protein_coding
description:
  Zn(II)-binding lipoprotein; Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). ZnuABC-mediated zinc transport is required for comF expression and competence development.


ensembl_gene_id: BSU02860
symbol: znuC
gene_biotype: protein_coding
description:
  Zn(II) transporter (ATP-binding protein); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for energy coupling to the transport system (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development.


ensembl_gene_id: BSU02870
symbol: znuB
gene_biotype: protein_coding
description:
  High affinity Zn(II) ABC transporter (permease); Part of the high-affinity ABC transporter complex ZnuABC involved in zinc import (Probable). Responsible for the translocation of the substrate across the membrane (By similarity). ZnuABC-mediated zinc transport is required for comF expression and competence development.


ensembl_gene_id: BSU02880
symbol: yceB
gene_biotype: protein_coding
description:
  Putative monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; To bacterial alkanal monooxygenase alpha and beta chains.


ensembl_gene_id: BSU02890
symbol: yceC
gene_biotype: protein_coding
description:
  Putative stress adaptation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the CAPAB/TerDEXZ family.


ensembl_gene_id: BSU02900
symbol: yceD
gene_biotype: protein_coding
description:
  Putative stress adaptation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU02920
symbol: yceF
gene_biotype: protein_coding
description:
  Putative stress adaptation transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU02940
symbol: yceH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the TelA family.


ensembl_gene_id: BSU02950
symbol: naiP
gene_biotype: protein_coding
description:
  Niacin permease; Probably involved in the uptake of amidated and deamidated forms of niacin. Increases the growth rate of E.coli that is unable to make niacin de novo; confers increased sensitivity to the toxic niacin analog 6-amino-nicotinamide to wild-type E.coli. There is probably another mechanism for niacin uptake.


ensembl_gene_id: BSU02980
symbol: opuAA
gene_biotype: protein_coding
description:
  Glycine betaine ABC transporter (ATP-binding protein); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine. Probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU02990
symbol: opuAB
gene_biotype: protein_coding
description:
  Glycine betaine ABC transporter (permease); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU03000
symbol: opuAC
gene_biotype: protein_coding
description:
  Glycine betaine ABC transporter (glycine betaine-binding lipoprotein); Involved in a multicomponent binding-protein-dependent transport system for glycine betaine.


ensembl_gene_id: BSU03010
symbol: amhX
gene_biotype: protein_coding
description:
  Amidohydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase M20 family.


ensembl_gene_id: BSU03040
symbol: amyE
gene_biotype: protein_coding
description:
  Alpha-amylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BSU03090
symbol: ycgF
gene_biotype: protein_coding
description:
  Putative aminoacid export permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU03100
symbol: ycgG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DcsA family.


ensembl_gene_id: BSU03110
symbol: ycgH
gene_biotype: protein_coding
description:
  Putative amino acid transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU03120
symbol: ycgI
gene_biotype: protein_coding
description:
  Putative methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU03130
symbol: nadE
gene_biotype: protein_coding
description:
  Ammonium-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.


ensembl_gene_id: BSU03150
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: BSU03170
symbol: ycgK
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BSU03180
symbol: cah
gene_biotype: protein_coding
description:
  Promiscuous acetyl xylan esterase-cephalosporin C deacetylase; Esterase that removed acetyl groups from a number of O- acetylated small substrates, such as acetylated xylose, short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages. Belongs to the carbohydrate esterase 7 family.


ensembl_gene_id: BSU03200
symbol: putB
gene_biotype: protein_coding
description:
  Proline oxidase; Converts proline to delta-1-pyrroline-5-carboxylate. Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.


ensembl_gene_id: BSU03210
symbol: putC
gene_biotype: protein_coding
description:
  1-pyrroline-5-carboxylate dehydrogenase; Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.


ensembl_gene_id: BSU03220
symbol: putP
gene_biotype: protein_coding
description:
  Proline permease; Catalyzes the high-affinity uptake of extracellular proline. Important for the use of proline as a sole carbon and energy source or a sole nitrogen source.


ensembl_gene_id: BSU03230
symbol: putR
gene_biotype: protein_coding
description:
  Transcriptional activator of proline degradation operon; Activates transcription of the putBCP operon. Requires proline as a coactivator.


ensembl_gene_id: BSU03260
symbol: ycgS
gene_biotype: protein_coding
description:
  Putative aromatic hydrocarbon hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the AB hydrolase superfamily.


ensembl_gene_id: BSU03270
symbol: ycgT
gene_biotype: protein_coding
description:
  Putative ferredoxin/thioredoxin reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU03280
symbol: nasF
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: BSU03290
symbol: nasE
gene_biotype: protein_coding
description:
  Assimilatory nitrite reductase subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity).


ensembl_gene_id: BSU03310
symbol: nasC
gene_biotype: protein_coding
description:
  Assimilatory nitrate reductase (catalytic subunit); Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.


ensembl_gene_id: BSU03340
symbol: folEB
gene_biotype: protein_coding
description:
  GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. Belongs to the GTP cyclohydrolase IV family.


ensembl_gene_id: BSU03350
symbol: yciB
gene_biotype: protein_coding
description:
  Putative metal uptake system lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU03360
symbol: zinT
gene_biotype: protein_coding
description:
  Zinc metallochaperone with NTPase activity; May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc.


ensembl_gene_id: BSU03370
symbol: yckA
gene_biotype: protein_coding
description:
  Putative ABC transporter (permease); Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.


ensembl_gene_id: BSU03380
symbol: yckB
gene_biotype: protein_coding
description:
  Putative ABC transporter (binding lipoprotein); Probably part of a binding-protein-dependent transport system; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: BSU03400
symbol: yckD
gene_biotype: protein_coding
description:
  Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU03410
symbol: bglC
gene_biotype: protein_coding
description:
  Aryl-phospho-beta-d-glucosidase; Is able to catalyze the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D-glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source. Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: BSU03420
symbol: nin
gene_biotype: protein_coding
description:
  Inhibitor of the DNA degrading activity of NucA (competence); Plays a role in the competence of cells to be transformed. It inhibits the activity of the DNA-entry nuclease.


ensembl_gene_id: BSU03430
symbol: nucA
gene_biotype: protein_coding
description:
  Endonuclease; By degrading DNA that enters the cell, plays a role in the competence of cells to be transformed. Degrades both double-stranded, linear and covalently closed circular DNA.


ensembl_gene_id: BSU03440
symbol: tlpC
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; receptor.


ensembl_gene_id: BSU03450
symbol: hxlB
gene_biotype: protein_coding
description:
  6-phospho-3-hexuloisomerase (PHI); Catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate. Together with HxlA, may act as a formaldehyde detoxification system.


ensembl_gene_id: BSU03460
symbol: hxlA
gene_biotype: protein_coding
description:
  3-hexulose-6-phosphate synthase (HPS); Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. Together with HxlB, may act as a formaldehyde detoxification system; Belongs to the HPS/KGPDC family. HPS subfamily.


ensembl_gene_id: BSU03480
symbol: srfAA
gene_biotype: protein_coding
description:
  Surfactin synthetase; This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu, Glu, Asp and Val. Activation sites for these AA consist of individual domains.


ensembl_gene_id: BSU03520
symbol: srfAD
gene_biotype: protein_coding
description:
  Surfactin synthetase; Probable thioesterase involved in the biosynthesis of surfactin; Belongs to the thioesterase family.


ensembl_gene_id: BSU03530
symbol: ycxA
gene_biotype: protein_coding
description:
  Putative carboxylate permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU03560
symbol: ycxD
gene_biotype: protein_coding
description:
  Putative PLP-dependent transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU03580
symbol: yczE
gene_biotype: protein_coding
description:
  N-terminal part of 4'-phosphopantetheinyl transferase (Surfactin synthetase-activating enzyme); Evidence 7: Gene remnant; Product type e: enzyme.


ensembl_gene_id: BSU03590
symbol: tcyC
gene_biotype: protein_coding
description:
  Cystine ABC transporter (ATP-binding protein); Part of the ABC transporter complex TcyABC involved in L- cystine import. Responsible for energy coupling to the transport system (Probable).


ensembl_gene_id: BSU03600
symbol: tcyB
gene_biotype: protein_coding
description:
  Cystine ABC transporter (permease); Part of the ABC transporter complex TcyABC involved in L- cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: BSU03610
symbol: tcyA
gene_biotype: protein_coding
description:
  Cystine ABC transporter (substrate-binding lipoprotein); Part of the ABC transporter complex TcyABC involved in L- cystine import.


ensembl_gene_id: BSU03620
symbol: bsdA
gene_biotype: protein_coding
description:
  HTH-type transcriptional regulator BsdA (LysR family); Could be a positive regulator of bsdBCD expression in response to salicylic acid.


ensembl_gene_id: BSU03630
symbol: bsdB
gene_biotype: protein_coding
description:
  Phenolic acid decarboxylase subunit BsdB; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase (By similarity); Belongs to the UbiX/PAD1 family. YclB subfamily.


ensembl_gene_id: BSU03640
symbol: bsdC
gene_biotype: protein_coding
description:
  Phenolic acid decarboxylase subunit BsdC; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. Phenolic acid decarboxylase that catalyzes the reversible decarboxylation of 4- hydroxybenzoate and vanillate. Could also catalyze the decarboxylation of salicylate (Probable). Is not active on di- and tri-hydroxybenzoate derivatives. Belongs to the UbiD family. YclC subfamily.


ensembl_gene_id: BSU03651
symbol: bsdD
gene_biotype: protein_coding
description:
  Phenolic acid decarboxylase subunit BsdD; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions, however the precise biochemical function of BsdD in metabolism of phenolic acid is unknown.


ensembl_gene_id: BSU03652
symbol: yclD
gene_biotype: protein_coding
description:
  Putative FMN-binding enzyme subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU03660
symbol: yclE
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the AB hydrolase superfamily.


ensembl_gene_id: BSU03670
symbol: dtpT
gene_biotype: protein_coding
description:
  Di-tripeptide-proton ABC symporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter.


ensembl_gene_id: BSU03680
symbol: yclG
gene_biotype: protein_coding
description:
  Putative uronase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU03700
symbol: gerKA
gene_biotype: protein_coding
description:
  Spore germination receptor subunit; Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl; Belongs to the GerABKA family.


ensembl_gene_id: BSU03710
symbol: gerKC
gene_biotype: protein_coding
description:
  Spore germination receptor subunit; Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl; Belongs to the GerABKC lipoprotein family.


ensembl_gene_id: BSU03720
symbol: gerKB
gene_biotype: protein_coding
description:
  Spore germination receptor subunit; Involved in the germination response to the combination of glucose, fructose, L-asparagine, and KCl; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.


ensembl_gene_id: BSU03730
symbol: yclH
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATPase component); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU03740
symbol: yclI
gene_biotype: protein_coding
description:
  Putative transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU03750
symbol: yclJ
gene_biotype: protein_coding
description:
  Two-component response regulator [YclK]; Could be member of the two-component regulatory system YclK/YclJ.


ensembl_gene_id: BSU03760
symbol: yclK
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YclJ]; Could be member of the two-component regulatory system YclK/YclJ. Potentially phosphorylates YclJ.


ensembl_gene_id: BSU03770
symbol: rapC
gene_biotype: protein_coding
description:
  Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family.


ensembl_gene_id: BSU03780
symbol: phrC
gene_biotype: protein_coding
description:
  Phosphatase RapC inhibitor; Inhibitor of the activity of phosphatase RapC; Belongs to the phr family.


ensembl_gene_id: BSU03788
symbol: yczM
gene_biotype: protein_coding
description:
  Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type f: factor.


ensembl_gene_id: BSU03789
symbol: yczN
gene_biotype: protein_coding
description:
  Putative spore and germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; factor.


ensembl_gene_id: BSU03790
symbol: yclM
gene_biotype: protein_coding
description:
  Aspartate kinase III; Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.


ensembl_gene_id: BSU03800
symbol: yclN
gene_biotype: protein_coding
description:
  Putative iron-siderophore ABC transporter (permease); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catecholate siderophore produced by many members of the B.cereus group, including B.anthracis. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: BSU03810
symbol: yclO
gene_biotype: protein_coding
description:
  Putative iron-siderophore ABC transporter (permease); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catecholate siderophore produced by many members of the B.cereus group, including B.anthracis. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU03820
symbol: yclP
gene_biotype: protein_coding
description:
  Putative iron-siderophore ABC transporter (ATP-binding protein); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catecholate siderophore produced by many members of the B.cereus group, including B.anthracis. Probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU03830
symbol: yclQ
gene_biotype: protein_coding
description:
  Putative iron-siderophore ABC transporter (binding lipoprotein); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catecholate siderophore produced by many members of the B.cereus group, including B.anthracis. Binds selectively iron-free and ferric petrobactin and the petrobactin precursor 3,4-dihydroxybenzoic acid (3,4-DHB); Belongs to the bacterial solute-binding protein 8 family.


ensembl_gene_id: BSU03850
symbol: ycnC
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU03860
symbol: nfrAB
gene_biotype: protein_coding
description:
  NADPH-FMN oxidoreductase (nitroreductase); Reduces FMNH(2) to FMN, with NADH or NADPH as reductant. It also reduces nitroaromatic compounds, quinones, chromates and azo dyes. It could supply the reduced form of FMN to luciferase-like protein and contribute to the degradation of aromatic compounds. Belongs to the flavin oxidoreductase frp family.


ensembl_gene_id: BSU03870
symbol: ycnE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Putative monooxygenase that may contribute to the degradation of aromatic compounds; Belongs to the LsrG family.


ensembl_gene_id: BSU03890
symbol: gabR
gene_biotype: protein_coding
description:
  Transcriptional regulator (GntR/MocR family) with PLP binding site; Activates the transcription of the gabTD operon. Is also a repressor of its own expression, both in the presence and absence of GABA. Binds specifically to the DNA region overlapping the -35 region of the gabT promoter and the -10 and +1 regions of the gabR promoter. Principally regulates the utilization of gamma-aminobutyrate. In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU03900
symbol: gabT
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU03910
symbol: gabD
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase; Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate.


ensembl_gene_id: BSU03930
symbol: gdh
gene_biotype: protein_coding
description:
  Glucose 1-dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU03950
symbol: ycnJ
gene_biotype: protein_coding
description:
  Putative copper import protein; Involved in uptake of extracellular oxidized copper under copper-limiting conditions; In the N-terminal section; belongs to the CopC family.


ensembl_gene_id: BSU03960
symbol: ycnK
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (DeoR family); May act as a negative transcriptional regulator of ycnJ in the presence of copper. May use copper as a corepressor.


ensembl_gene_id: BSU03970
symbol: ycnL
gene_biotype: protein_coding
description:
  Putative reductase or disulfide isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU03981
symbol: mtlA
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) mannitol-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.


ensembl_gene_id: BSU03982
symbol: mtlF
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) mannitol-specific enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.


ensembl_gene_id: BSU03990
symbol: mtlD
gene_biotype: protein_coding
description:
  Mannitol-1-phosphate dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU04000
symbol: ycsA
gene_biotype: protein_coding
description:
  Putative tartrate dehydrogenase; Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso- tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: BSU04010
symbol: sipU
gene_biotype: protein_coding
description:
  Type I signal peptidase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase S26 family.


ensembl_gene_id: BSU04020
symbol: yczH
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the dienelactone hydrolase family.


ensembl_gene_id: BSU04030
symbol: ycsD
gene_biotype: protein_coding
description:
  Putative hydroxyacyl-(acyl carrier protein) dehydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the thioester dehydratase family. FabZ subfamily.


ensembl_gene_id: BSU04040
symbol: ycsE
gene_biotype: protein_coding
description:
  Putative phosphatase; Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro. To a lesser extent, may also catalyze the dephosphorylation of a broad range of substrates such as phosphorylated sugars and triphosphate nucleotides in vitro.


ensembl_gene_id: BSU04050
symbol: ycsF
gene_biotype: protein_coding
description:
  Putative nitrogen-containing heterocycle degradation enzyme; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. Belongs to the LamB/PxpA family.


ensembl_gene_id: BSU04060
symbol: ycsG
gene_biotype: protein_coding
description:
  Putative branched chain amino acids transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU04070
symbol: ycsI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321; Belongs to the D-glutamate cyclase family.


ensembl_gene_id: BSU04080
symbol: kipI
gene_biotype: protein_coding
description:
  Putative inhibitor of the autophosphorylation reaction of KinA; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, is a potent inhibitor of the autophosphorylation reaction of kinase A (kinA) and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. Is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is non- competitive with re [...]


ensembl_gene_id: BSU04090
symbol: kipA
gene_biotype: protein_coding
description:
  Putative hydrolase subunit antagonist of KipI; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. In addition, counteracts the inhibitory action of PxpB (KipI) on sporulation, by binding to PxpB and preventing its function as an inhibitor of kinase A.


ensembl_gene_id: BSU04100
symbol: kipR
gene_biotype: protein_coding
description:
  Transcriptional regulator (IclR family); Transcriptional repressor of the kip gene-containing operon.


ensembl_gene_id: BSU04110
symbol: lipC
gene_biotype: protein_coding
description:
  Spore coat phospholipase B; Lipase involved in spore germination. Belongs to the 'GDSL' lipolytic enzyme family.


ensembl_gene_id: BSU04140
symbol: pbpC
gene_biotype: protein_coding
description:
  Penicillin-binding lipoprotein 3; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.


ensembl_gene_id: BSU04150
symbol: ycsN
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.


ensembl_gene_id: BSU04160
symbol: mtlR
gene_biotype: protein_coding
description:
  Transcriptional regulator; Positively regulates the expression of the mtlAFD operon involved in the uptake and catabolism of mannitol.


ensembl_gene_id: BSU04170
symbol: ydaB
gene_biotype: protein_coding
description:
  Putative acyl-CoA ligase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU04190
symbol: ydaD
gene_biotype: protein_coding
description:
  Putative dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU04200
symbol: ydaE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166; Belongs to the D-lyxose ketol-isomerase family.


ensembl_gene_id: BSU04210
symbol: ydaF
gene_biotype: protein_coding
description:
  Putative ribosomal protein N-acetyltransferase; Putative N-acetyltransferase. May act on ribosomal proteins (Potential); Belongs to the acetyltransferase family.


ensembl_gene_id: BSU04220
symbol: ydaG
gene_biotype: protein_coding
description:
  Putative general stress protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU04230
symbol: ydaH
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. May serve as a defense mechanism against naturally occurring MurJ antagonists.


ensembl_gene_id: BSU04250
symbol: lrpC
gene_biotype: protein_coding
description:
  Transcriptional regulator (Lrp/AsnC family); Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition.


ensembl_gene_id: BSU04260
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]


ensembl_gene_id: BSU04270
symbol: ydaJ
gene_biotype: protein_coding
description:
  Putative glycosyl hydrolase lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.


ensembl_gene_id: BSU04280
symbol: ydaK
gene_biotype: protein_coding
description:
  Putative membrane protein with diguanylate cyclase domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU04300
symbol: ydaM
gene_biotype: protein_coding
description:
  Putative glycosyltransferase associated to biofilm formation; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU04310
symbol: ydaN
gene_biotype: protein_coding
description:
  Putative regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU04330
symbol: mutT
gene_biotype: protein_coding
description:
  Putative NTP pyrophosphohydrolase; May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions. MutT specifically degrades 8-oxo- dGTP to the monophosphate (By similarity). Functions, in conjunction with ytkD, to protect vegetatively growing cells from DNA-damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not [...]


ensembl_gene_id: BSU04340
symbol: ydaP
gene_biotype: protein_coding
description:
  Putative enzyme with pyruvate as substrate; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU04359
symbol: ydzK
gene_biotype: protein_coding
description:
  Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU04360
symbol: mntH
gene_biotype: protein_coding
description:
  Manganese transporter; H(+)-stimulated, divalent metal cation uptake system. Involved in manganese uptake. Can probably also transport cadmium, cobalt, copper and zinc, but not iron. May be the predominant transporter of manganese during logarithmic phase growth.


ensembl_gene_id: BSU04400
symbol: gsiB
gene_biotype: protein_coding
description:
  General stress protein; Involved in an adaptive response to nutrient deprivation other than sporulation.


ensembl_gene_id: BSU04410
symbol: ydbB
gene_biotype: protein_coding
description:
  Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the SchB/CurC family.


ensembl_gene_id: BSU04430
symbol: ydbD
gene_biotype: protein_coding
description:
  Putative manganese-containing catalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the manganese catalase family.


ensembl_gene_id: BSU04440
symbol: dctB
gene_biotype: protein_coding
description:
  C4-dicarboxylate binding protein; Part of the binding-protein-dependent transport system for uptake of C4-dicarboxylates. Responsible for growth on fumarate and succinate but not malate. Is not directly involved in C4-dicarboxylate uptake, but plays a sensory role in the DctS/DctR two-component system which regulates the expression of the dctA C4-dicarboxylate transporter; Belongs to the bacterial solute-binding protein 7 family.


ensembl_gene_id: BSU04450
symbol: dctS
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Member of the two-component regulatory system DctS/DctR. Probably activates DctR by phosphorylation (By similarity). Essential for expression of dctP.


ensembl_gene_id: BSU04460
symbol: dctR
gene_biotype: protein_coding
description:
  Two-component response regulator; Member of the two-component regulatory system DctS/DctR. Essential for expression of dctP.


ensembl_gene_id: BSU04470
symbol: dctP
gene_biotype: protein_coding
description:
  C4-dicarboxylate transport protein; Responsible for the transport of succinate and fumarate, but not malate, across the membrane.


ensembl_gene_id: BSU04490
symbol: ydbJ
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU04500
symbol: ydbK
gene_biotype: protein_coding
description:
  Putative efflux ABC-transporter (permease component); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU04520
symbol: ydbM
gene_biotype: protein_coding
description:
  Putative acyl-CoA dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acyl-CoA dehydrogenase family.


ensembl_gene_id: BSU04530
symbol: fbpB
gene_biotype: protein_coding
description:
  Regulator of iron homeostasis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU04540
symbol: ydbO
gene_biotype: protein_coding
description:
  Putative cation efflux system; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU04550
symbol: ydbP
gene_biotype: protein_coding
description:
  Putative thioredoxin or thiol-disulfide isomerase; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family.


ensembl_gene_id: BSU04570
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: BSU04580
symbol: cshA
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; The most abundant DEAD-box RNA helicase. An ATP-dependent RNA helicase with RNA-dependent ATPase activity. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. In vitro, unwinds dsRNA in both 5'- and 3'- directions. Plays a role in ribosomal 50S subunit assembly. Its deletion leads to changes in mRNA levels for over 200 transcripts.


ensembl_gene_id: BSU04610
symbol: ydcA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15616571, 15849754, 16850406.


ensembl_gene_id: BSU04620
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-acyl carrier protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of fatty acid acyl-carrier-protein ACP. Also modifies the D- alanyl carrier protein but fails to recognize PCP and AcpK, an acyl carrier protein of secondary metabolism.


ensembl_gene_id: BSU04640
symbol: alrA
gene_biotype: protein_coding
description:
  D-alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: BSU04650
symbol: ndoAI
gene_biotype: protein_coding
description:
  Antitoxin EndoAI; Antitoxin component of a type II toxin-antitoxin (TA) system. Antitoxin that directly inhibits activity of EndoA in vitro. Upon expression in E.coli counteracts inhibitory effect of endoribonuclease EndoA. The EndoA-EndoAI complex does not seem to bind its own promoter.


ensembl_gene_id: BSU04660
symbol: ndoA
gene_biotype: protein_coding
description:
  Endoribonuclease toxin; Toxic component of a type II toxin-antitoxin (TA) system. Specific for 5'-UACAU-3' sequences, cleaving after the first U. Yields cleavage products with 3' phosphate and 5' hydroxyl groups. Cannot digest substrate with a UUdUACAUAA cleavage site. Overexpression is toxic for cell growth (shown in E.coli), probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antitoxin EndoAI. Toxin activity cannot be inhibited by MazE from E.coli. The EndoA-EndoAI complex does not seem to bind its own promoter.


ensembl_gene_id: BSU04670
symbol: rsbRA
gene_biotype: protein_coding
description:
  Component of the piezosome (stressosome); Acts as a positive regulator of sigma-B activity in response to salt and heat stress by stimulating the activity of the RsbT kinase toward RsbS in vitro. Negative regulator of sigma-B activity. Non-phosphorylated RsbS binds to RsbT, preventing its association with RsbU. Requires any one of RsbRA, RsbRB, RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated, they release RsbT, which can then bind and activate RsbU.


ensembl_gene_id: BSU04680
symbol: rsbS
gene_biotype: protein_coding
description:
  Antagonist of RsbT; Negative regulator of sigma-B activity. Non-phosphorylated RsbS binds to RsbT, preventing its association with RsbU. Requires any one of RsbRA, RsbRB, RsbRC or RsbRD to sequester RsbT. When RsbS and the RsbR paralog(s) are phosphorylated, they release RsbT, which can then bind and activate RsbU.


ensembl_gene_id: BSU04690
symbol: rsbT
gene_biotype: protein_coding
description:
  Switch protein/serine-threonine kinase; Provides the crucial link between the upstream module (communication of environmental stress) and the downstream module (integration of the environmental signals with signals of energy stress) that compose the signal transduction pathway controlling the sigma-B factor. Phosphorylates and inactivates its specific antagonist protein RsbS thanks to its serine kinase activity. Upon phosphorylation of RsbS, RsbT is released to stimulate RsbU, a PP2C phosphatase, thereby initiating the signaling cascade that ultimately activates sigma-B. The activity o [...]


ensembl_gene_id: BSU04700
symbol: rsbU
gene_biotype: protein_coding
description:
  Serine phosphatase; Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to environmental stress conveyed from the RsbXST module.


ensembl_gene_id: BSU04710
symbol: rsbV
gene_biotype: protein_coding
description:
  Anti-anti-sigma factor (antagonist of RsbW); Positive regulator of sigma-B activity. Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B. When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B.


ensembl_gene_id: BSU04720
symbol: rsbW
gene_biotype: protein_coding
description:
  Switch protein/serine kinase and anti-sigma factor (inhibitory sigma-B binding protein); Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).


ensembl_gene_id: BSU04730
symbol: sigB
gene_biotype: protein_coding
description:
  RNA polymerase sigma-37 factor (sigma(B)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation. May play a role in the ability of the bacterium to adapt to various stresses but is not essential for its survival under these conditions. Positively regulates expression of its own operon; Belongs to the sigma-70 fac [...]


ensembl_gene_id: BSU04740
symbol: rsbX
gene_biotype: protein_coding
description:
  Serine phosphatase; Negative regulator of sigma-B activity. Dephosphorylates RsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communicating sigma-B protein levels.


ensembl_gene_id: BSU04760
symbol: ydcG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0310 family.


ensembl_gene_id: BSU04770
symbol: ydcH
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU04780
symbol: ydcI
gene_biotype: protein_coding
description:
  Putative RNA helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU04790
symbol: ydcK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the SprT family.


ensembl_gene_id: BSU04800
symbol: ydcL
gene_biotype: protein_coding
description:
  Putative phage integrase; Putative integrase that is involved in the insertion of the integrative and conjugative element ICEBs1. Required for the excision of ICEBs1 from the donor cell genome and subsequent integration in the recipient cell genome. Appears not to be transferred through the mating pore. Integration of ICEBs1 involves an attachment site in the chromosome, attB, and a site in the circular form of ICEBs1, attICEBs1.


ensembl_gene_id: BSU04810
symbol: immA
gene_biotype: protein_coding
description:
  Site-specific protease cleaving ImmR; Involved in the regulation of horizontal gene transfer through the integrative and conjugative element ICEBs1. Required for degradation of the ICEBs1 repressor protein ImmR/YdcN.


ensembl_gene_id: BSU04820
symbol: immR
gene_biotype: protein_coding
description:
  Phage element (ICEBs1)transcriptional regulator (Xre family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU04830
symbol: sacV
gene_biotype: protein_coding
description:
  Transcriptional regulator; Required for the excision of the integrative and conjugative element ICEBs1. Excision of ICEBs1 requires two sites, attL and attR, at the left and right ends of the integrated ICEBs1.


ensembl_gene_id: BSU04860
symbol: ydcQ
gene_biotype: protein_coding
description:
  Putative DNA wielding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU04870
symbol: ydcR
gene_biotype: protein_coding
description:
  Putative replication protein; Probable DNA relaxase involved in the transfer of the integrative and conjugative element ICEBs1. Required for the transfer of ICEBs1. Probably mediates conjugation of ICEBs1 by nicking at oriT on the conjugative element and facilitates the translocation of a single strand of ICEBs1 DNA through a transmembrane conjugation pore into the recipient cell; Belongs to the plasmid replication initiation factor family.


ensembl_gene_id: BSU04970
symbol: yddH
gene_biotype: protein_coding
description:
  Cell wall hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the peptidase C40 family.


ensembl_gene_id: BSU05010
symbol: rapI
gene_biotype: protein_coding
description:
  Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family.


ensembl_gene_id: BSU05020
symbol: phrI
gene_biotype: protein_coding
description:
  Secreted regulator of the activity of phosphatase RapI; Inhibitor of the activity of phosphatase RapI.


ensembl_gene_id: BSU05030
symbol: yddM
gene_biotype: protein_coding
description:
  Putative helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU05040
symbol: yddN
gene_biotype: protein_coding
description:
  Putative alkanal monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; To bacterial alkanal monooxygenase alpha and beta chains.


ensembl_gene_id: BSU05050
symbol: lrpA
gene_biotype: protein_coding
description:
  Transcriptional regulator (Lrp/AsnC family); Negative regulation of glyA transcription and kinB-dependent sporulation.


ensembl_gene_id: BSU05070
symbol: yddQ
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the isochorismatase family.


ensembl_gene_id: BSU05080
symbol: yddR
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the UPF0173 family.


ensembl_gene_id: BSU05099
symbol: ydzM
gene_biotype: protein_coding
description:
  Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU05110
symbol: ydeA
gene_biotype: protein_coding
description:
  Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase C56 family.


ensembl_gene_id: BSU05120
symbol: cspC
gene_biotype: protein_coding
description:
  Cold-shock protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU05130
symbol: ydeB
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs to the CarD family.


ensembl_gene_id: BSU05150
symbol: ydeC
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU05170
symbol: ydeE
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU05250
symbol: ydeM
gene_biotype: protein_coding
description:
  Putative dehydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU05260
symbol: ydeN
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RBBP9 family.


ensembl_gene_id: BSU05300
symbol: ydeQ
gene_biotype: protein_coding
description:
  Putative NAD(P)H oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NAD(P)H dehydrogenase (quinone) family.


ensembl_gene_id: BSU05320
symbol: ydeS
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (TetR/AcrR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU05330
symbol: aseR
gene_biotype: protein_coding
description:
  Transcriptional regulator (metals sensing ArsR-SmtB repressors family); Metal-responsive transcriptional regulator that represses transcription of the aseR-ydfA operon by binding specifically to its promoter. Binding of arsenite or antimonite causes the repressor to dissociate from the DNA.


ensembl_gene_id: BSU05340
symbol: ydfA
gene_biotype: protein_coding
description:
  Putative metal-anion antiporter protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU05380
symbol: ydfE
gene_biotype: protein_coding
description:
  Putative flavoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU05410
symbol: ydfH
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YdfI]; Member of the two-component regulatory system YdfH/YdfI. May activate YdfI by phosphorylation.


ensembl_gene_id: BSU05420
symbol: ydfI
gene_biotype: protein_coding
description:
  Two-component response regulator [YdfH]; Member of the two-component regulatory system YdfH/YdfI. Regulates the transcription of ydfJ by binding to its promoter region.


ensembl_gene_id: BSU05430
symbol: ydfJ
gene_biotype: protein_coding
description:
  Putative proton metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.


ensembl_gene_id: BSU05440
symbol: nap
gene_biotype: protein_coding
description:
  Carboxylesterase NP; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the AB hydrolase superfamily.


ensembl_gene_id: BSU05460
symbol: ydfL
gene_biotype: protein_coding
description:
  Putative transcriptional regulator of efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU05470
symbol: ydfM
gene_biotype: protein_coding
description:
  Putative divalent cation efflux transporter; Primary efflux pump for manganese. May prevent manganese intoxication; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: BSU05480
symbol: ydfN
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Putative nitroreductase that may contribute to the degradation of aromatic compounds.


ensembl_gene_id: BSU05490
symbol: ydfO
gene_biotype: protein_coding
description:
  Putative dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds.


ensembl_gene_id: BSU05500
symbol: ydfP
gene_biotype: protein_coding
description:
  Putative membrane bound oxidoreductase; Putative oxidoreductase that may contribute to the degradation of aromatic compounds.


ensembl_gene_id: BSU05510
symbol: ydfQ
gene_biotype: protein_coding
description:
  Putative thioredoxin or thiol-disulfide isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU05529
symbol: ydzR
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19383706, 20709900; Belongs to the GerPA/GerPF family.


ensembl_gene_id: BSU05550
symbol: cotP
gene_biotype: protein_coding
description:
  Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU05600
symbol: ydgE
gene_biotype: protein_coding
description:
  Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family.


ensembl_gene_id: BSU05610
symbol: vmlR
gene_biotype: protein_coding
description:
  ATP-binding cassette efflux transporter; Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics. Makes contact with the PTC and both ribosomal subunits. Induces conformational changes in the P-site, which allows it to dislodge the antibiotic from its PTC binding site. Binds to ribosomes either directly following translation initation or subsequent to E tRNA release during elongation. Involved in resistance to a narrow spectrum of antibiotics (the streptogramin A antibiotic virginiamycin M, the lincosamide antibiotic [...]


ensembl_gene_id: BSU05640
symbol: ydgG
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU05650
symbol: ydgH
gene_biotype: protein_coding
description:
  Putative membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.


ensembl_gene_id: BSU05700
symbol: ydhC
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU05710
symbol: ydhD
gene_biotype: protein_coding
description:
  Spore cortex lytic enzyme; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process; Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.


ensembl_gene_id: BSU05720
symbol: ydhE
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the UDP-glycosyltransferase family.


ensembl_gene_id: BSU05730
symbol: ydhF
gene_biotype: protein_coding
description:
  Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein.


ensembl_gene_id: BSU05740
symbol: phoB
gene_biotype: protein_coding
description:
  Alkaline phosphatase III; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the alkaline phosphatase family.


ensembl_gene_id: BSU05750
symbol: fra
gene_biotype: protein_coding
description:
  Frataxin; Possible global iron distributor for the cell. Promotes the biosynthesis of iron-sulfur clusters by delivering Fe to the iron- sulfur cluster assembly scaffold protein SufU. In the presence of SufS and L-cysteine reconstitutes Fe-S clusters on SufU, which when further incubated with apo-aconitase (citB) reconstitutes aconitase activity. Able to reconstitute an Fe-S cluster on Thermotoga maritima IscU.


ensembl_gene_id: BSU05770
symbol: ydhI
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU05780
symbol: ydhJ
gene_biotype: protein_coding
description:
  Putative metal-dependent phosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU05800
symbol: pbuE
gene_biotype: protein_coding
description:
  Hypoxanthine efflux transporter; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and inosine, as well as purine bases guanine, adenine and hypoxanthine, and purine base analogs 2,6-diaminopurine, 6- mercaptopurine and 2-fluoroadenine. Therefore plays a role in maintaining the cellular purine base pools and protecting cells against toxic purine base analogs. Modulates expression of the purR and G-box regulons.


ensembl_gene_id: BSU05810
symbol: gmuB
gene_biotype: protein_coding
description:
  Oligo-alpha-mannoside phosphotransferase system enzyme IIB; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II GmuABC PTS system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose.


ensembl_gene_id: BSU05820
symbol: gmuA
gene_biotype: protein_coding
description:
  Oligo-alpha-mannoside phosphotransferase system enzyme IIA; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II GmuABC PTS system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose.


ensembl_gene_id: BSU05830
symbol: gmuC
gene_biotype: protein_coding
description:
  Oligo-alpha-mannoside phosphotransferase system enzyme IIC; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II GmuABC PTS system is involved in the transport of oligo- glucomannans such as cellobiose or mannobiose.


ensembl_gene_id: BSU05840
symbol: gmuD
gene_biotype: protein_coding
description:
  Mannoside-phospho-beta-d-glucosidase; Phospho-beta-D-glucosidase that seems to be involved in the degradation of glucomannan. Is also capable of hydrolyzing aryl- phospho-beta-D-glucosides, although very weakly, and plays only a minor role, if any, in the degradation of these substrates in vivo. Belongs to the glycosyl hydrolase 1 family.


ensembl_gene_id: BSU05850
symbol: gmuR
gene_biotype: protein_coding
description:
  Transcriptional regulator (GntR family); Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan.


ensembl_gene_id: BSU05870
symbol: gmuF
gene_biotype: protein_coding
description:
  Phosphohexomutase; Seems to be involved in the degradation of glucomannan. Belongs to the mannose-6-phosphate isomerase type 1 family.


ensembl_gene_id: BSU05880
symbol: gmuG
gene_biotype: protein_coding
description:
  Exported mannan endo-1,4-beta-mannosidase; Involved in the degradation of glucomannan. Catalyzes the endo hydrolysis of beta-1,4-linked mannan, galactomannan and glucomannan; Belongs to the glycosyl hydrolase 26 family.


ensembl_gene_id: BSU05900
symbol: thiL
gene_biotype: protein_coding
description:
  tRNA-Asp; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: BSU05910
symbol: tsaE
gene_biotype: protein_coding
description:
  tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB; this reaction does not require ATP in vitro. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro, which is modulated by the oligo [...]


ensembl_gene_id: BSU05920
symbol: tsaB
gene_biotype: protein_coding
description:
  tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.


ensembl_gene_id: BSU05930
symbol: rimI
gene_biotype: protein_coding
description:
  Ribosomal protein S18 alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: BSU05940
symbol: tsaD
gene_biotype: protein_coding
description:
  tRNA(NNU) t(6)A37 threonylcarbamoyladenosine modification; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB; this reaction does not require ATP in vitro. TsaD likely plays a direct catalytic role in this reaction. Belongs to the KAE1 / TsaD family.


ensembl_gene_id: BSU05950
symbol: ydiF
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily. ABCF family. YdiF subfamily.


ensembl_gene_id: BSU05960
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: BSU05970
symbol: rex
gene_biotype: protein_coding
description:
  Transcription repressor of cydABCD and yjlC-ndh expression; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: BSU05980
symbol: tatAY
gene_biotype: protein_coding
description:
  Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. Required for YwbN secretion; Belongs to the TatA/E family.


ensembl_gene_id: BSU05990
symbol: tatCY
gene_biotype: protein_coding
description:
  Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Required for YwbN secretion; Belongs to the TatC family.


ensembl_gene_id: BSU06010
symbol: ydiL
gene_biotype: protein_coding
description:
  Putative membrane protease; May function as endopeptidase which proteolytically removes the C-terminal three residues of farnesylated peptides containing the CAAX motif where C is cysteine, A is an aliphatic amino acid and X is any amino acid; Belongs to the peptidase U48 family.


ensembl_gene_id: BSU06020
symbol: groES
gene_biotype: protein_coding
description:
  Chaperonin small subunit; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.


ensembl_gene_id: BSU06030
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin large subunit; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: BSU06060
symbol: bsuMA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; This methylase may recognize the double-stranded sequence CTCGAG, causing specific methylation on C-? on both strands, and protects the DNA from cleavage by the BsuMI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: BSU06070
symbol: bsuMB
gene_biotype: protein_coding
description:
  DNA-methyltransferase (cytosine-specific); This methylase may recognize the double-stranded sequence CTCGAG, causing specific methylation on C-? on both strands, and protects the DNA from cleavage by the BsuMI endonuclease. Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: BSU06090
symbol: bsuRA
gene_biotype: protein_coding
description:
  Putative phosphomannomutase; Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.


ensembl_gene_id: BSU06100
symbol: bsuRB
gene_biotype: protein_coding
description:
  Type-2 restriction enzyme BsuMI component BsuRB (YdiS); Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.


ensembl_gene_id: BSU06110
symbol: bsuRC
gene_biotype: protein_coding
description:
  Type-2 restriction enzyme BsuMI component BsuRC (YdjA); Recognizes the double-stranded sequence CTCGAG; the cleavage site is unknown.


ensembl_gene_id: BSU06140
symbol: gutR
gene_biotype: protein_coding
description:
  Transcriptional regulator of the glucitol operon; Activator of the glucitol dehydrogenase gene (gutB).


ensembl_gene_id: BSU06150
symbol: gutB
gene_biotype: protein_coding
description:
  Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2- oxidized products D-fructose, D-xylulose and L-sorbose, respectively.


ensembl_gene_id: BSU06160
symbol: gutP
gene_biotype: protein_coding
description:
  H+-glucitol symporter; Probably involved in glucitol uptake; Belongs to the sodium:galactoside symporter (TC 2.A.2) family.


ensembl_gene_id: BSU06170
symbol: ydjE
gene_biotype: protein_coding
description:
  Putative sugar kinase (ribokinase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: BSU06180
symbol: pspA
gene_biotype: protein_coding
description:
  Phage shock protein A homolog; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU06190
symbol: ydjG
gene_biotype: protein_coding
description:
  Putative phage replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU06220
symbol: ydjJ
gene_biotype: protein_coding
description:
  Putative membrane associated potassium channel; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU06240
symbol: bdhA
gene_biotype: protein_coding
description:
  Acetoin reductase/2,3-butanediol dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU06280
symbol: ydjP
gene_biotype: protein_coding
description:
  Putative peroxydase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU06310
symbol: gabP
gene_biotype: protein_coding
description:
  Gamma-aminobutyrate (GABA) permease; High-affinity uptake system for GABA. Functions also as a low-affinity proline importer; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.


ensembl_gene_id: BSU06320
symbol: yeaB
gene_biotype: protein_coding
description:
  Putative cation efflux transporter; Secondary manganese efflux system. May prevent manganese intoxication; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: BSU06330
symbol: yeaC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the MoxR family.


ensembl_gene_id: BSU06370
symbol: pbuG
gene_biotype: protein_coding
description:
  Hypoxanthine/guanine permease; Involved in the uptake of the purine bases hypoxanthine and guanine; Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily.


ensembl_gene_id: BSU06420
symbol: purE
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: BSU06430
symbol: purK
gene_biotype: protein_coding
description:
  N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family.


ensembl_gene_id: BSU06440
symbol: purB
gene_biotype: protein_coding
description:
  Adenylosuccinate lyase; Influences the affinity of glutamyl--tRNA ligase for its substrates and increases its thermostability; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: BSU06450
symbol: purC
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole succinocarboxamide synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the SAICAR synthetase family.


ensembl_gene_id: BSU06460
symbol: purS
gene_biotype: protein_coding
description:
  Factor required for phosphoribosylformylglycinamidine synthetase activity; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and Pu [...]


ensembl_gene_id: BSU06470
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]


ensembl_gene_id: BSU06480
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assis [...]


ensembl_gene_id: BSU06490
symbol: purF
gene_biotype: protein_coding
description:
  Glutamine phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: BSU06500
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU06510
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: BSU06520
symbol: purH
gene_biotype: protein_coding
description:
  Fused phosphoribosylaminoimidazole carboxy formyl formyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU06530
symbol: purD
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU06540
symbol: yezC
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (Lrp/AsnC family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU06550
symbol: yecA
gene_biotype: protein_coding
description:
  Putative amino acid/polyamine permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU06560
symbol: yerA
gene_biotype: protein_coding
description:
  Putative adenine deaminase YerA; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU06590
symbol: yerD
gene_biotype: protein_coding
description:
  Putative flavoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU06600
symbol: pcrB
gene_biotype: protein_coding
description:
  Heptaprenylglyceryl-phosphate synthase; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales. To a much lesser extent, is also able to use geranyl diphosphate (GPP; C10) and geranylgeranyl diphosphate (GGPP; C20) as the prenyl donors, but not farnesyl pyrophosphate (FPP; C15). Ca [...]


ensembl_gene_id: BSU06610
symbol: pcrA
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase; DNA helicase used for plasmid rolling-circle replication and also involved in UV repair.


ensembl_gene_id: BSU06620
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: BSU06640
symbol: yerI
gene_biotype: protein_coding
description:
  Putative kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: BSU06650
symbol: sapB
gene_biotype: protein_coding
description:
  Membrane component; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.


ensembl_gene_id: BSU06660
symbol: opuE
gene_biotype: protein_coding
description:
  Proline transporter; Catalyzes the uptake of extracellular proline under high- osmolarity growth conditions. Essential for the use of proline present in the environment as an osmoprotectant.


ensembl_gene_id: BSU06670
symbol: gatC
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase (subunit C); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity); Belongs to the GatC family.


ensembl_gene_id: BSU06680
symbol: gatA
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase (subunit A); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: BSU06690
symbol: gatB
gene_biotype: protein_coding
description:
  glutamyl-tRNA(Gln) amidotransferase (subunit B); Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: BSU06710
symbol: swrC
gene_biotype: protein_coding
description:
  Transporter involved in surfactin self-resistance; Required for self-resistance to surfactin, an antimicrobial lipopeptide surfactant produced by B.subtilis. Also required for swarming motility; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: BSU06720
symbol: dagK
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway. Is more active toward long-chain DAG compared with short-chain DAG. Is not able to phosphorylate substrates other than DAG, such as monoacylglycerol, ceramide, undecaprenol, phosphatidylinositol, or sphingosine; Belongs to the diacylglycerol/lipid kinase family.


ensembl_gene_id: BSU06730
symbol: rlmCD
gene_biotype: protein_coding
description:
  Methyltransferase of m5U747 and m5U1939 in 23S RNA; Catalyzes the formation of 5-methyl-uridine at positions 747 (m5U747) and 1939 (m5U1939) in 23S rRNA.


ensembl_gene_id: BSU06740
symbol: yefB
gene_biotype: protein_coding
description:
  Putative site-specific recombinase / invertase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU06750
symbol: yefC
gene_biotype: protein_coding
description:
  Putative resolvase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the site-specific recombinase resolvase family.


ensembl_gene_id: BSU06760
symbol: yeeA
gene_biotype: protein_coding
description:
  Putative restriction type II methylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU06770
symbol: yeeB
gene_biotype: protein_coding
description:
  Putative DNA helicase / endonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the helicase family.


ensembl_gene_id: BSU06780
symbol: yeeC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU06811
symbol: yezG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Probable antitoxin component of a type II toxin-antitoxin (TA) system. Probably neutralizes the ability to inhibit growth of cognate toxin YeeF. Probably does not have antitoxin activity on other toxins with the LXG toxin domain (Probable).


ensembl_gene_id: BSU06812
symbol: yeeF
gene_biotype: protein_coding
description:
  Putative DNA binding protein; Probable toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 500-669) may have RNase activity and probably inhibits growth. Its toxic effects are probably neutralized by its cognate antitoxin YezG, but not by antitoxins specific to other toxins with the LXG domain (Probable).


ensembl_gene_id: BSU06820
symbol: yeeG
gene_biotype: protein_coding
description:
  Putative phage receptor protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU06839
symbol: phrH
gene_biotype: protein_coding
description:
  Hexapeptide inhibitor of regulatory cascade; Inhibitor of the activity of phosphatase RapH. May inhibit the rapH promoter after import into the cytoplasm.


ensembl_gene_id: BSU06860
symbol: yezE
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (TetR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU06870
symbol: yesE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the limonene-1,2-epoxide hydrolase family.


ensembl_gene_id: BSU06880
symbol: yesF
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NmrA-type oxidoreductase family.


ensembl_gene_id: BSU06890
symbol: cotJA
gene_biotype: protein_coding
description:
  Component of the inner spore coat; The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat.


ensembl_gene_id: BSU06920
symbol: yesJ
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family.


ensembl_gene_id: BSU06950
symbol: yesM
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YesN]; Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation.


ensembl_gene_id: BSU06970
symbol: yesO
gene_biotype: protein_coding
description:
  Pectin degradation byproducts-binding lipoprotein; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BSU06980
symbol: rhgP
gene_biotype: protein_coding
description:
  Rhamnogalacturonan permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.


ensembl_gene_id: BSU07000
symbol: rhgH
gene_biotype: protein_coding
description:
  Rhamnogalacturonan hydrolase; Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D-glucuronic acid at the non-reducing terminus, although the active pockets of YesR and UGL are very similar. Belongs to the glycosyl hydrolase 105 family.


ensembl_gene_id: BSU07010
symbol: yesS
gene_biotype: protein_coding
description:
  Transcriptional regulator (AraC/XylS family); Probable transcription factor regulating the pathway responsible for rhamnogalacturonan depolymerization.


ensembl_gene_id: BSU07020
symbol: rhgT
gene_biotype: protein_coding
description:
  Rhamnogalacturonan acetylesterase; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. This enzyme has a broad substrate specificity, and shows strong preference for glucose pentaacetate, beta-naphthylacetate, and p-nitrophenyl acetate (pNPA). Also active toward acetylated xylan.


ensembl_gene_id: BSU07030
symbol: yesU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16781735, 17449691.


ensembl_gene_id: BSU07040
symbol: yesV
gene_biotype: protein_coding
description:
  Putative integral inner membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU07050
symbol: rhgW
gene_biotype: protein_coding
description:
  Rhamnogalacturonan endolyase; Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan, polygalacturonic acid, pectic acid and pectin ; Belongs to the polysaccharide lyase 11 family.


ensembl_gene_id: BSU07060
symbol: rhgX
gene_biotype: protein_coding
description:
  Rhamnogalacturonan exolyase YesX; Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases disaccharide products. Degrades rhamnogalacturonan, polygalacturonic acid and pectic acid. Has very low activity on pectin ; Belongs to the polysaccharide lyase 11 family.


ensembl_gene_id: BSU07070
symbol: yesY
gene_biotype: protein_coding
description:
  Rhamnogalacturonan acetylesterase; May play a role in the degradation of rhamnogalacturonan derived from plant cell walls. Probably has broad substrate specificity and may degrade several types of acetylated substrates. Belongs to the 'GDSL' lipolytic enzyme family.


ensembl_gene_id: BSU07080
symbol: rhgZ
gene_biotype: protein_coding
description:
  Beta-galacturonidase; May play a role in the degradation of rhamnogalacturonan derived from plant cell walls; Belongs to the glycosyl hydrolase 42 family.


ensembl_gene_id: BSU07100
symbol: lplA
gene_biotype: protein_coding
description:
  Lipoprotein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.


ensembl_gene_id: BSU07110
symbol: lplB
gene_biotype: protein_coding
description:
  Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU07130
symbol: lplD
gene_biotype: protein_coding
description:
  Putative glycosidase; Alpha-galacturonidase able to catalyze the hydrolysis of the chromogenic substrate p-nitrophenyl-alpha-D-galacturonic acid (pNPalphaGalUA), and of the probable natural substrate alpha-1,4-di- galacturonate (GalUA(2)). Can neither hydrolyze pNPbetaGalUA, nor the stereoisomeric pNPalphaGlcUA. Does not display alpha- or beta- glucosidase activity as it fails to hydrolyze melibiose, raffinose, lactose and the chromogenic analogs, pNPalphaGal and pNPbetaGal. Cannot use the following compounds as substrates: pNP-N-acetyl-alpha- and beta-D-galactosaminide, pNP-N-acetyl-a [...]


ensembl_gene_id: BSU07150
symbol: hmoA
gene_biotype: protein_coding
description:
  Heme-degrading monooxygenase; Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron; Belongs to the antibiotic biosynthesis monooxygenase family.


ensembl_gene_id: BSU07160
symbol: yetH
gene_biotype: protein_coding
description:
  Putative lyase/dioxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU07200
symbol: yetJ
gene_biotype: protein_coding
description:
  Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU07230
symbol: yetM
gene_biotype: protein_coding
description:
  Putative hydroxylase/monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU07250
symbol: cypD
gene_biotype: protein_coding
description:
  Putative bifunctional P-450/NADPH-P450 reductase 1; Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of long-chain fatty acids, with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 position. Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain. Is also able to catalyze efficient oxidation of sodium dodecyl sulfate (SDS).


ensembl_gene_id: BSU07260
symbol: ltaSA
gene_biotype: protein_coding
description:
  Exported glycerol phosphate lipoteichoic acid synthetase and anion-binding protein; Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate.


ensembl_gene_id: BSU07270
symbol: yfnH
gene_biotype: protein_coding
description:
  Putative glucose-1-phosphate cytidylyltransferase; Catalyzes the transfer of a CMP moiety from CTP to glucose 1- phosphate.


ensembl_gene_id: BSU07280
symbol: yfnG
gene_biotype: protein_coding
description:
  Putative CDP-sugar-dehydratase/epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU07290
symbol: yfnF
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU07300
symbol: yfnE
gene_biotype: protein_coding
description:
  Putative glycosyltransferase (complex carbohydrate synthase); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase 2 family.


ensembl_gene_id: BSU07310
symbol: yfnD
gene_biotype: protein_coding
description:
  Putative glycosyltransferase (complex carbohydrate synthase); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU07330
symbol: yfnB
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HAD-like hydrolase superfamily. YjjG family.


ensembl_gene_id: BSU07350
symbol: yfmT
gene_biotype: protein_coding
description:
  Putative aldehyde dehydrogenase; A benzaldehyde dehydrogenase able to act on substrates with 3- and 4-hydroxy and methoxy substitutions; converts vanillin (4- hydroxy-3-methoxybenzaldehyde) to vanillic acid in vitro. The physiological substrate is unknown.


ensembl_gene_id: BSU07360
symbol: yfmS
gene_biotype: protein_coding
description:
  Putative chemotaxis sensory transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity).


ensembl_gene_id: BSU07370
symbol: uup
gene_biotype: protein_coding
description:
  Putative ABC protein involved in RecA-independent precise excision of transposons; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU07390
symbol: yfmP
gene_biotype: protein_coding
description:
  Transcriptional regulator (MerR family) of metal efflux transporter expression; Repressor of the yfmOP operon. A mutation in yfmP leads to overexpression of yfmO, probably causing a decrease in cellular copper that is eventually responsible for a reduced copper induction of copZA.


ensembl_gene_id: BSU07400
symbol: yfmO
gene_biotype: protein_coding
description:
  Metal efflux transporter; Acts to efflux copper or a copper complex. It is possible that YfmO could contribute to copper resistance. Belongs to the major facilitator superfamily.


ensembl_gene_id: BSU07420
symbol: yfmM
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU07430
symbol: yfmL
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase; A probable DEAD-box RNA helicase that plays a role in ribosomal 50S subunit assembly. May be a non-specific RNA helicase. Belongs to the DEAD box helicase family.


ensembl_gene_id: BSU07450
symbol: yfmJ
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds; Belongs to the NADP-dependent oxidoreductase L4BD family.


ensembl_gene_id: BSU07490
symbol: yfmF
gene_biotype: protein_coding
description:
  Iron-dicitrate ABC transporter (ATP-binding protein); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Responsible for energy coupling to the transport system (Probable).


ensembl_gene_id: BSU07500
symbol: yfmE
gene_biotype: protein_coding
description:
  Iron-dicitrate ABC transporter (permease); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Involved in the translocation of the substrate across the membrane (Probable).


ensembl_gene_id: BSU07520
symbol: yfmC
gene_biotype: protein_coding
description:
  Iron-dicitrate ABC transporter (binding lipoprotein); Part of the ABC transporter complex YfmCDEF involved in citrate-dependent Fe(3+) import. Binds citrate-dependent Fe(3+) and delivers it to the surface of YfmDE (Probable). Belongs to the bacterial solute-binding protein 8 family.


ensembl_gene_id: BSU07550
symbol: yflT
gene_biotype: protein_coding
description:
  Heat stress induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU07580
symbol: citS
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Functions probably as a membrane-associated protein kinase that phosphorylates CitT in response to environmental citrate or Mg(2+)-citrate complex.


ensembl_gene_id: BSU07590
symbol: citT
gene_biotype: protein_coding
description:
  Two-component response regulator; Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM- yflN operon.


ensembl_gene_id: BSU07600
symbol: yflP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0065 (bug) family.


ensembl_gene_id: BSU07610
symbol: citM
gene_biotype: protein_coding
description:
  Transporter of divalent metal ions/citrate complexes; Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+), Mn(2+), Co(2+), and Zn(2+); Belongs to the CitM (TC 2.A.11) transporter family.


ensembl_gene_id: BSU07620
symbol: yflN
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the metallo-beta-lactamase superfamily.


ensembl_gene_id: BSU07630
symbol: nosA
gene_biotype: protein_coding
description:
  Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily.


ensembl_gene_id: BSU07640
symbol: yflL
gene_biotype: protein_coding
description:
  Putative acylphosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acylphosphatase family.


ensembl_gene_id: BSU07650
symbol: yflK
gene_biotype: protein_coding
description:
  Putative sulfur carrier; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.


ensembl_gene_id: BSU07680
symbol: yflH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1070366, 1266368.


ensembl_gene_id: BSU07690
symbol: mapB
gene_biotype: protein_coding
description:
  Methionine aminopeptidase B; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.


ensembl_gene_id: BSU07700
symbol: nagP
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) N-acetylglucosamine-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylglucosamine transport (By similarity).


ensembl_gene_id: BSU07710
symbol: ltaSB
gene_biotype: protein_coding
description:
  Enzyme responsible for polyglycerolphosphate LTA synthesis; Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate; Belongs to the LTA synthase family.


ensembl_gene_id: BSU07750
symbol: yflA
gene_biotype: protein_coding
description:
  Putative aminoacid transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU07760
symbol: yfkT
gene_biotype: protein_coding
description:
  Putative spore germination integral inner membrane protein; May be involved in spore germination. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.


ensembl_gene_id: BSU07780
symbol: yfkR
gene_biotype: protein_coding
description:
  Putative spore germination protein; May be involved in spore germination. Belongs to the GerABKC lipoprotein family.


ensembl_gene_id: BSU07790
symbol: yfkQ
gene_biotype: protein_coding
description:
  Putative spore germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU07800
symbol: treP
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) trehalose-specific enzyme IIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in trehalose transport.


ensembl_gene_id: BSU07810
symbol: treA
gene_biotype: protein_coding
description:
  Trehalose-6-phosphate hydrolase; Hydrolyzes trehalose-6-phosphate to glucose and glucose 6- phosphate. Can also very effectively hydrolyzes p-nitrophenyl-alpha-D- glucopyranoside, but not lactose, maltose, sucrose or sucrose-6- phosphate. Trehalose is also hydrolyzed, but to a much smaller extent than trehalose-6-phosphate; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BSU07820
symbol: treR
gene_biotype: protein_coding
description:
  Transcriptional regulator (GntR family); Repressor for the trePA operon. It is able to bind trehalose- 6-phosphate.


ensembl_gene_id: BSU07830
symbol: nfsB
gene_biotype: protein_coding
description:
  NAD(P)H-flavin oxidoreductase (nitroreductase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the nitroreductase family.


ensembl_gene_id: BSU07840
symbol: yfkN
gene_biotype: protein_coding
description:
  Exported 2',3'-cyclic-nucleotide 2'-phosphodiesterase, 2' (or 3') nucleotidase and 5' nucleotidase; Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'-nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3',5'-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium, under conditions of phosphate shortage.


ensembl_gene_id: BSU07850
symbol: yfkM
gene_biotype: protein_coding
description:
  General stress protein 18; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins.


ensembl_gene_id: BSU07860
symbol: yfkL
gene_biotype: protein_coding
description:
  Efflux transporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: BSU07870
symbol: yfkK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0435 family.


ensembl_gene_id: BSU07880
symbol: yfkJ
gene_biotype: protein_coding
description:
  Protein-tyrosine-phosphatase; Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance.


ensembl_gene_id: BSU07890
symbol: yfkI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210.


ensembl_gene_id: BSU07900
symbol: rbn
gene_biotype: protein_coding
description:
  Putative ribonuclease BN; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU07920
symbol: yfkE
gene_biotype: protein_coding
description:
  Putative H+/Ca2+ antiporter; Ca(+)/H(+) antiporter that extrudes calcium in exchange for external protons. Does not transport sodium or potassium. Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.


ensembl_gene_id: BSU07940
symbol: yfkC
gene_biotype: protein_coding
description:
  Putative mechanosensitive ion channel; May play a role in resistance to osmotic downshock. Belongs to the MscS (TC 1.A.23) family.


ensembl_gene_id: BSU07955
symbol: yfkA
gene_biotype: protein_coding
description:
  Putative Fe-S oxidoreductase, radical SAM superfamily; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU07980
symbol: pdaA
gene_biotype: protein_coding
description:
  Exported N-acetylmuramic acid deacetylase; Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in glycan strands of peptidoglycan, leading to the formation of muramic delta-lactam residues in spore cortex, after transpeptidation of deacetylated muramic acid residues. PdaA probably carries out both deacetylation and lactam ring formation and requires the product of CwlD activity on peptidoglycan as a substrate. Is required for germination. Cannot use chitin oligomer (hexa-N- acetylchitohexaose) as a substrate; Belongs to the polysaccharide deacetylase family.


ensembl_gene_id: BSU07990
symbol: yfjR
gene_biotype: protein_coding
description:
  Putative beta-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HIBADH-related family.


ensembl_gene_id: BSU08000
symbol: yfjQ
gene_biotype: protein_coding
description:
  Putative divalent cation transport protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: BSU08010
symbol: yfjP
gene_biotype: protein_coding
description:
  Putative DNA-modified purine glycosidase; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine, 3-methylguanine, 7-methylguanine, O2-methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions; Belongs to the alkylbase DNA glycosidase AlkA family.


ensembl_gene_id: BSU08020
symbol: yfjO
gene_biotype: protein_coding
description:
  Putative RNA methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: BSU08030
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase 2; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family.


ensembl_gene_id: BSU08060
symbol: acoA
gene_biotype: protein_coding
description:
  Acetoin dehydrogenase E1 component (TPP-dependent alpha subunit); Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde. The alpha subunit is probably the catalytic subunit of the enzyme (By similarity).


ensembl_gene_id: BSU08070
symbol: acoB
gene_biotype: protein_coding
description:
  Acetoin dehydrogenase E1 component (TPP-dependent beta subunit); Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde.


ensembl_gene_id: BSU08080
symbol: acoC
gene_biotype: protein_coding
description:
  Acetoin dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU08090
symbol: acoL
gene_biotype: protein_coding
description:
  Acetoin dehydrogenase E3 component (dihydrolipoamide dehydrogenase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: BSU08100
symbol: acoR
gene_biotype: protein_coding
description:
  Transcriptional regulator; Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex.


ensembl_gene_id: BSU08110
symbol: sspH
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the SspH family.


ensembl_gene_id: BSU08170
symbol: yfjA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the WXG100 family.


ensembl_gene_id: BSU08180
symbol: malA
gene_biotype: protein_coding
description:
  6-phospho-alpha-glucosidase; Hydrolyzes maltose-6'-phosphate and trehalose-6'-phosphate. Is involved in the catabolism of alpha-glycosides accumulated via a phosphoenolpyruvate-dependent maltose phosphotransferase system (PEP- PTS). Is also able to significantly catalyze the hydrolysis of both 6- phospho-alpha- and 6-phospho-beta-glucosides containing activated leaving groups such as p-nitrophenol and does so with retention and inversion, respectively, of the substrate anomeric configuration.


ensembl_gene_id: BSU08190
symbol: malR
gene_biotype: protein_coding
description:
  Transcriptional activator of the Mal operon; Positive regulator of the glv operon expression, which consists of GlvA, GlvR and GlvC.


ensembl_gene_id: BSU08200
symbol: malP
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) maltose-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport.


ensembl_gene_id: BSU08210
symbol: malQ
gene_biotype: protein_coding
description:
  Maltose and maltodextrin ABC transporter subunit (ATP-binding protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter.


ensembl_gene_id: BSU08220
symbol: yfiC
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU08230
symbol: catD
gene_biotype: protein_coding
description:
  Catechol-2,3-dioxygenase membrane subunit; Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol.


ensembl_gene_id: BSU08240
symbol: catE
gene_biotype: protein_coding
description:
  Catechol-2,3-dioxygenase subunit; Involved in the meta cleavage of catechol to 2-hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol.


ensembl_gene_id: BSU08250
symbol: yfiF
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (AraC/XylS family; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU08260
symbol: yfiG
gene_biotype: protein_coding
description:
  Putative sugar transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU08270
symbol: yfiH
gene_biotype: protein_coding
description:
  Putative sugar-phosphate epimerase/isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU08280
symbol: yfiI
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the Gfo/Idh/MocA family.


ensembl_gene_id: BSU08290
symbol: yfiJ
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YfiK]; Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Member of the two-component regulatory system LnrJ/LnrK, which induces expression of the LnrLMN ABC transporter in response to linearmycins and other polyenes. Acts as a specific sensor for linearmycin, either directly through binding or indirectly through membrane perturbation. Probably activates LnrK by phosphorylation. May also promote biofilm formation.


ensembl_gene_id: BSU08300
symbol: yfiK
gene_biotype: protein_coding
description:
  Two-component response regulator [YfiJ]; Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Member of the two-component regulatory system LnrJ/LnrK, which induces expression of the LnrLMN ABC transporter in response to linearmycins and other polyenes. Probably binds to the promoter region of the lnrLMN operon and directly regulates its expression (Probable). May also promote biofilm formation.


ensembl_gene_id: BSU08310
symbol: yfiL
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Part of the ABC transporter complex LnrLMN that probably facilitates linearmycin removal from the membrane. Responsible for energy coupling to the transport system. Also mediates KinC-dependent biofilm morphology.


ensembl_gene_id: BSU08320
symbol: yfiM
gene_biotype: protein_coding
description:
  Putative ABC transporter (permease); Required for resistance to linearmycins, a family of antibiotic-specialized metabolites produced by some streptomycetes. Part of the ABC transporter complex LnrLMN that probably facilitates linearmycin removal from the membrane. Responsible for the translocation of the substrate across the membrane. Also mediates KinC-dependent biofilm morphology ; Belongs to the ABC-2 integral membrane protein family.


ensembl_gene_id: BSU08340
symbol: padR
gene_biotype: protein_coding
description:
  Transcriptional regulator of PadC; Negative transcriptional regulator of padC phenolic acid decarboxylase.


ensembl_gene_id: BSU08350
symbol: estB
gene_biotype: protein_coding
description:
  Secreted esterase / lipase; An esterase which preferentially hydrolyzes triacylglyceride substrates with short chain fatty acids (less than C10) with the maximum activity towards tricaprylin (C8:0). Active against p- nitrophenylesters with fatty acid chain lengths from C6 to C18.


ensembl_gene_id: BSU08360
symbol: yfiQ
gene_biotype: protein_coding
description:
  Putative membrane component involved in biofilm formation; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU08370
symbol: yfiR
gene_biotype: protein_coding
description:
  Transcriptional regulator (TetR/AcrR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU08390
symbol: bst
gene_biotype: protein_coding
description:
  Bacillithiol S-transferase; Possible metal-dependent hydrolase; Belongs to the metal hydrolase YfiT family.


ensembl_gene_id: BSU08425
symbol: mprF
gene_biotype: protein_coding
description:
  Phosphatidylglycerol lysyltransferase involved in lysinylation of phospholipids; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects B.subtilis against its own CAMPs and against those produced by competiting microorganisms (bacteriocins). In fact, the modification of anionic phosphatidylglycerol with po [...]


ensembl_gene_id: BSU08440
symbol: yfiY
gene_biotype: protein_coding
description:
  Putative iron(III) dicitrate transporter binding lipoprotein; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable).


ensembl_gene_id: BSU08450
symbol: yfiZ
gene_biotype: protein_coding
description:
  iron(III) siderophore transport permease; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen.


ensembl_gene_id: BSU08470
symbol: yfhB
gene_biotype: protein_coding
description:
  Putative isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the PhzF family.


ensembl_gene_id: BSU08480
symbol: yfhC
gene_biotype: protein_coding
description:
  Putative oxidoreductase (nitroreductase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU08510
symbol: yfhF
gene_biotype: protein_coding
description:
  Putative nucleotide binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.


ensembl_gene_id: BSU08550
symbol: sspK
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the SspK family.


ensembl_gene_id: BSU08580
symbol: yfhL
gene_biotype: protein_coding
description:
  SdpC immunity factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU08590
symbol: yfhM
gene_biotype: protein_coding
description:
  Epoxide hydrolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.


ensembl_gene_id: BSU08600
symbol: csbB
gene_biotype: protein_coding
description:
  Putative glycosyl transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase 2 family. GtrB subfamily.


ensembl_gene_id: BSU08620
symbol: yfhP
gene_biotype: protein_coding
description:
  Putative membrane hydrolase; May act as a negative regulator for the transcription of mutY, fabL, sspE and yfhP.


ensembl_gene_id: BSU08630
symbol: mutY
gene_biotype: protein_coding
description:
  A/G-specific adenine glycosylase or DNA-(apurinic or apyrimidinic site) lyase; Base excision repair (BER) glycosylase that initiates repair of A:oxoG to C:G by removing the inappropriately paired adenine base from the DNA backbone, generating an abasic site product. 8-oxoguanine (oxoG) is a genotoxic DNA lesion resulting from oxidation of guanine; this residue is misread by replicative DNA polymerases, that insert adenine instead of cytosine opposite the oxidized damaged base. Shows a powerful dicrimination of A versus C, since it does not cleave cytosine in oxoG:C pairs. May also be a [...]


ensembl_gene_id: BSU08640
symbol: yfhS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10463184.


ensembl_gene_id: BSU08650
symbol: fabL
gene_biotype: protein_coding
description:
  Enoyl-acyl carrier protein reductase III; Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It confers resistance to triclosan. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU08660
symbol: sspE
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein (gamma-type SASP); SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light.


ensembl_gene_id: BSU08680
symbol: ygaC
gene_biotype: protein_coding
description:
  Putative factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0374 family.


ensembl_gene_id: BSU08690
symbol: ygaD
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); May be involved in multidrug export. Transmembrane domains (TMD) form a pore in the cell membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity); Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU08710
symbol: gsaB
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde aminotransferase, class III aminotransferase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.


ensembl_gene_id: BSU08720
symbol: ygaF
gene_biotype: protein_coding
description:
  Putative bacterioferritin comigratory protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events; Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.


ensembl_gene_id: BSU08730
symbol: perR
gene_biotype: protein_coding
description:
  Transcriptional regulator (Fur family); Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA; Belongs to the Fur family.


ensembl_gene_id: BSU08760
symbol: spo0M
gene_biotype: protein_coding
description:
  Sporulation-control gene; Controls the expression of spo0A and is required to pass the morphological stage 0 of sporulation; Belongs to the spo0M family.


ensembl_gene_id: BSU08780
symbol: ygaJ
gene_biotype: protein_coding
description:
  Putative peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase S51 family.


ensembl_gene_id: BSU08790
symbol: thiC
gene_biotype: protein_coding
description:
  Biosynthesis of the pyrimidine moiety from 5-aminoimidazole ribotide (AIR) (thiamin biosynthesis); Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: BSU08800
symbol: ygaK
gene_biotype: protein_coding
description:
  Putative FAD-dependent oxido-reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU08810
symbol: senS
gene_biotype: protein_coding
description:
  Transcriptional regulator (activator); Regulates the expression of extracellular-protein genes of Bacillus subtilis.


ensembl_gene_id: BSU08820
symbol: katA
gene_biotype: protein_coding
description:
  Vegetative catalase 1; Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.


ensembl_gene_id: BSU08830
symbol: ssuB
gene_biotype: protein_coding
description:
  Aliphatic sulfonate ABC transporter (ATP-binding protein); Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable). Is also involved in taurine transport.


ensembl_gene_id: BSU08840
symbol: ssuA
gene_biotype: protein_coding
description:
  Aliphatic sulfonate ABC transporter (binding lipoprotein); Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein.


ensembl_gene_id: BSU08850
symbol: ssuC
gene_biotype: protein_coding
description:
  Aliphatic sulfonate ABC transporter (permease); Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU08860
symbol: ssuD
gene_biotype: protein_coding
description:
  FMNH2-dependent aliphatic sulfonate monooxygenase; Catalyzes the desulfonation of aliphatic sulfonates.


ensembl_gene_id: BSU08870
symbol: ygaN
gene_biotype: protein_coding
description:
  Putative sulfur-related oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU08880
symbol: rpsNB
gene_biotype: protein_coding
description:
  Alternative ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: BSU08899
symbol: ygzD
gene_biotype: protein_coding
description:
  Putative HTH-type transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU08910
symbol: queG
gene_biotype: protein_coding
description:
  Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: BSU08930
symbol: trmL
gene_biotype: protein_coding
description:
  tRNA (cytidine(34)-2'-O)-methyltransferase TrmL; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.


ensembl_gene_id: BSU08940
symbol: yhbD
gene_biotype: protein_coding
description:
  Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU08970
symbol: prkA
gene_biotype: protein_coding
description:
  Serine protein kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the PrkA family.


ensembl_gene_id: BSU08980
symbol: yhbH
gene_biotype: protein_coding
description:
  Factor involved in shape determination (sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU09020
symbol: yhcB
gene_biotype: protein_coding
description:
  NADH:quinone oxidoreductase associated to stress; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU09050
symbol: yhcE
gene_biotype: protein_coding
description:
  Putative integral inner membrane orphan protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU09070
symbol: yhcG
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU09100
symbol: cspB
gene_biotype: protein_coding
description:
  Major cold-shock protein, RNA helicase co-factor, RNA co-chaperone; Binds to the pentamer sequences ATTGG and CCAAT with highest affinity in single-stranded DNA, and also to other sequences. Has greater affinity for ATTGG than CCAAT. Can act as transcriptional activator of cold shock genes by recognizing putative ATTGG-box elements present in promoter regions of genes induced under cold shock conditions.


ensembl_gene_id: BSU09110
symbol: yhcJ
gene_biotype: protein_coding
description:
  Putative ABC transporter (binding lipoprotein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.


ensembl_gene_id: BSU09120
symbol: yhcK
gene_biotype: protein_coding
description:
  Putative diguanylate cyclase or phosphodiesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU09130
symbol: tcyP
gene_biotype: protein_coding
description:
  Sodium-cystine symporter; Mediates uptake of L-cystine, the oxidized form of L- cysteine. Although it is more specific for L-cystine, it could also transport a much broader range of amino acids and sulfur compounds including S-methylcysteine; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: BSU09150
symbol: yhcN
gene_biotype: protein_coding
description:
  Putative lipoprotein; Probably contributes, directly or indirectly, to early events in germination. May play a role in spore outgrowth.


ensembl_gene_id: BSU09190
symbol: yhcR
gene_biotype: protein_coding
description:
  Non specific extracellular endonuclease cleaving RNA and DNA; Sugar-nonspecific endonuclease that yields nucleotide 3'- monophosphate products. No 5'-nucleotidase activity was detected, using 5'-AMP as the substrate, in the presence of diverse divalent metals and with various pH values.


ensembl_gene_id: BSU09200
symbol: srtA
gene_biotype: protein_coding
description:
  Sortase A; Transpeptidase that anchors surface proteins to the cell wall. Recognizes and modifies its substrate by proteolytic cleavage of a C-terminal sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the sortase and its substrate, which is then transferred and covalently attached to the cell wall (Probable). This sortase recognizes a Leu-Pro-Asp-Thr-Ser/Ala (LPDTS/A) motif. It has two substrates, YhcR and YfkN. Belongs to the bacterial sortase family. Class D subfamily.


ensembl_gene_id: BSU09210
symbol: yhcT
gene_biotype: protein_coding
description:
  Putative RNA pseudouridine synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU09230
symbol: yhcV
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU09240
symbol: glpW
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type pe: putative enzyme.


ensembl_gene_id: BSU09250
symbol: yhcX
gene_biotype: protein_coding
description:
  Putative amidohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.


ensembl_gene_id: BSU09260
symbol: yhxA
gene_biotype: protein_coding
description:
  Hypothetical protein; Essential for glycerol catabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU09270
symbol: glpP
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate responding transcription antiterminator; Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA. May also regulate expression of the glpFK operon.


ensembl_gene_id: BSU09280
symbol: glpF
gene_biotype: protein_coding
description:
  Glycerol permease; Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: BSU09290
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: BSU09300
symbol: glpD
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate oxidase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU09310
symbol: pgcA
gene_biotype: protein_coding
description:
  Alpha-phosphoglucomutase; Catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers, since glucose-1-phosphate is the precursor of UDP-glucose, which serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required fo [...]


ensembl_gene_id: BSU09320
symbol: yhcY
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YhcZ]; Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation.


ensembl_gene_id: BSU09340
symbol: yhdA
gene_biotype: protein_coding
description:
  Oxidoreductase, NAD(P)H-FMN and ferric iron reductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity; Belongs to the azoreductase type 2 family.


ensembl_gene_id: BSU09370
symbol: lytF
gene_biotype: protein_coding
description:
  gamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin); Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan. LytF is necessary and sufficient for vegetative daughter cell separation, and also seems to play a role in cell autolysis.


ensembl_gene_id: BSU09380
symbol: nsrR
gene_biotype: protein_coding
description:
  NO-dependent activator of the ResDE regulon; Nitric oxide-responsive transcriptional regulator. It represses the expression of flavohemoprotein hmp and the nitrite reductase nasD. Probably plays a role in the up-regulation of the resDE regulon in the presence of nitric oxide.


ensembl_gene_id: BSU09400
symbol: spoVR
gene_biotype: protein_coding
description:
  Involved in spore cortex synthesis (stage V sporulation); Appears to be involved in spore cortex formation.


ensembl_gene_id: BSU09410
symbol: phoA
gene_biotype: protein_coding
description:
  Alkaline phosphatase A; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the alkaline phosphatase family.


ensembl_gene_id: BSU09420
symbol: lytE
gene_biotype: protein_coding
description:
  Cell wall hydrolase; Cell wall hydrolase that cleaves gamma-D-glutamate-meso- diaminopimelate bonds in peptidoglycan (By similarity). Seems to play a role in cell separation during vegetative growth.


ensembl_gene_id: BSU09430
symbol: citR
gene_biotype: protein_coding
description:
  Transcriptional regulator CitR (LysR family); Negative regulatory protein for the citA gene for citrate synthase I; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BSU09440
symbol: citA
gene_biotype: protein_coding
description:
  Citrate synthase I; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect; Belongs to the citrate synthase family.


ensembl_gene_id: BSU09450
symbol: yhdF
gene_biotype: protein_coding
description:
  Putative NAD(P)-dependent dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU09460
symbol: bcaP
gene_biotype: protein_coding
description:
  Branched-chain amino acid transporter; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; Belongs to the amino acid-polyamine-organocation (APC) superfamily.


ensembl_gene_id: BSU09470
symbol: yhdH
gene_biotype: protein_coding
description:
  Putative sodium-dependent transporter; Putative sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: BSU09490
symbol: yhdJ
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransferase family.


ensembl_gene_id: BSU09500
symbol: yhdK
gene_biotype: protein_coding
description:
  Negative regulator of the activity of sigma-M; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.


ensembl_gene_id: BSU09520
symbol: sigM
gene_biotype: protein_coding
description:
  RNA polymerase ECF (extracytoplasmic function)-type sigma factor (sigma(M)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by a cognate anti-sigma factor (YhdL) until released. This sigma factor is involved in the maintenance of membrane and cell wall integrity in response to environmental stresses including salt, acid, ethanol and antibiotics stress. Partially regulates transcription from a number of genes including disA.


ensembl_gene_id: BSU09530
symbol: yhdN
gene_biotype: protein_coding
description:
  Aldo/keto reductase specific for NADPH; Aldo-keto reductase (AKR) that displays broad substrate specificity in vitro. Is able to reduce the standard AKR substrates DL- glyceraldehyde, D-erythrose, methylglyoxal, p-nitrobenzaldehyde, benzaldehyde and butyraldehyde, in the presence of NADPH. Cannot use NADH as a cosubstrate. Does not act on glucose, 2-pyridine carboxyaldehyde, fructose and xylose. The physiological function of this enzyme is not clear. May play a role in bacterial stress response and/or in detoxification of reactive aldehydes. Belongs to the aldo/keto reductase family. A [...]


ensembl_gene_id: BSU09540
symbol: plsC
gene_biotype: protein_coding
description:
  1-acylglycerol-phosphate (1-acyl-G3P) acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: BSU09550
symbol: yhdP
gene_biotype: protein_coding
description:
  Putative transporter or sensor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: BSU09570
symbol: yhdR
gene_biotype: protein_coding
description:
  Putative aspartate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU09600
symbol: crcBA
gene_biotype: protein_coding
description:
  Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: BSU09620
symbol: yhdW
gene_biotype: protein_coding
description:
  Putative glycerophosphodiester phosphodiesterase; Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to sn-glycerol 3-phosphate (G3P) and the corresponding alcohols.


ensembl_gene_id: BSU09650
symbol: srtN
gene_biotype: protein_coding
description:
  Sirtuin NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.


ensembl_gene_id: BSU09660
symbol: yheN
gene_biotype: protein_coding
description:
  Putative polysaccharide deacetylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU09670
symbol: dat
gene_biotype: protein_coding
description:
  D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essen [...]


ensembl_gene_id: BSU09680
symbol: nhaC
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Is a secondary, electrogenic Na(+)/H(+) antiporter that catalyzes Na(+) uptake and proton efflux. Makes modest contributions to pH homeostasis in the alkaline range of pH but is not contributor to Na(+) resistance. Appears to have a repressive effect on growth and on alkaline phosphatases production in the presence of sodium, by affecting the transcription of the phoP/phoR two-component regulatory system.


ensembl_gene_id: BSU09710
symbol: yheI
gene_biotype: protein_coding
description:
  Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI; Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU09720
symbol: yheH
gene_biotype: protein_coding
description:
  Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH; Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU09730
symbol: yheG
gene_biotype: protein_coding
description:
  Putative NADH-flavin oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU09750
symbol: sspB
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein (beta-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.


ensembl_gene_id: BSU09780
symbol: yheC
gene_biotype: protein_coding
description:
  Spore coat associated protein, similar to YheD; Involved in sporulation; Belongs to the YheC/YheD family.


ensembl_gene_id: BSU09790
symbol: yheB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16684363.


ensembl_gene_id: BSU09800
symbol: yheA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19429628; Belongs to the UPF0342 family.


ensembl_gene_id: BSU09810
symbol: yhaZ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290.


ensembl_gene_id: BSU09830
symbol: yhaX
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU09840
symbol: hemZ
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Involved in the biosynthesis of porphyrin-containing compound; Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemZ subfamily.


ensembl_gene_id: BSU09850
symbol: yhaU
gene_biotype: protein_coding
description:
  Transporter involved in K+ efflux; Potassium/proton antiporter that mediates the efflux of potassium ions from the cell. Can also mediate rubidium/proton antiport, but has no permeability for sodium or lithium ions. In the absence of KhtT, does not have antiport activity, but can catalyze potassium efflux. Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis, via activation by S-lactoyl-BSH of the antiporter activity, leading to cytoplasmic acidification and methylglyoxal resistance ; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transpo [...]


ensembl_gene_id: BSU09860
symbol: khtT
gene_biotype: protein_coding
description:
  K+/H+ antiporter for K+ efflux; Required for activity of the potassium/proton antiporter KhtU. Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis.


ensembl_gene_id: BSU09870
symbol: khtS
gene_biotype: protein_coding
description:
  K+/H+ antiporter for K+ efflux; Modulates the activity of the potassium/proton antiporter KhtU. Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis.


ensembl_gene_id: BSU09880
symbol: yhaR
gene_biotype: protein_coding
description:
  Putative dehydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU09890
symbol: yhaQ
gene_biotype: protein_coding
description:
  Na+-efflux ABC transporter (ATP-binding protein); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: BSU09900
symbol: yhaP
gene_biotype: protein_coding
description:
  Na+ exporter (ABC permease); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; To M.jannaschii MJ1024.


ensembl_gene_id: BSU09910
symbol: yhaO
gene_biotype: protein_coding
description:
  Putative exonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the metallophosphoesterase superfamily.


ensembl_gene_id: BSU09920
symbol: sbcE
gene_biotype: protein_coding
description:
  ATPase involved in DNA double strand break repair and recombination; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU09930
symbol: yhaM
gene_biotype: protein_coding
description:
  3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family.


ensembl_gene_id: BSU09950
symbol: prsA
gene_biotype: protein_coding
description:
  Molecular chaperone lipoprotein; Essential protein that plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins. Has PPIase activity but it is not essential for its function in vivo; Belongs to the PrsA family.


ensembl_gene_id: BSU09958
symbol: sscA
gene_biotype: protein_coding
description:
  Spore assembly and germination protein; Spore protein involved in the assembly of several components of the spore coat, including CotB, CotG and CotH, and in spore germination.


ensembl_gene_id: BSU09959
symbol: sscB
gene_biotype: protein_coding
description:
  Spore and germination protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU09965
symbol: yhaJ
gene_biotype: protein_coding
description:
  Putative bacteriocin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU09990
symbol: scoC
gene_biotype: protein_coding
description:
  HTH-type transcriptional regulator Hpr; Negative regulator of protease production and sporulation. Acts by binding directly to the promoter of protease genes (aprE and nprE), and by repressing oligopeptide permease operons (appABCDF and oppABCDF), thereby preventing uptake of oligopeptides required for initiation of sporulation. Acts with SinR as a corepressor of epr expression.


ensembl_gene_id: BSU10000
symbol: yhaH
gene_biotype: protein_coding
description:
  Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: BSU10010
symbol: trpP
gene_biotype: protein_coding
description:
  Tryptophan transporter; Probably involved in tryptophan uptake; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. TrpP subfamily.


ensembl_gene_id: BSU10020
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: BSU10030
symbol: hinT
gene_biotype: protein_coding
description:
  Hit-family hydrolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU10040
symbol: ecsA
gene_biotype: protein_coding
description:
  ABC transporter (ATP-binding protein); Has a role in exoprotein production, sporulation and competence.


ensembl_gene_id: BSU10050
symbol: ecsB
gene_biotype: protein_coding
description:
  ABC transporter (membrane protein); Presumed to form part of an ABC-transporter, it may form a transport channel.


ensembl_gene_id: BSU10070
symbol: yhaA
gene_biotype: protein_coding
description:
  Putative amidohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU10100
symbol: hmoB
gene_biotype: protein_coding
description:
  Heme-degrading monooxygenase; Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron; Belongs to the antibiotic biosynthesis monooxygenase family.


ensembl_gene_id: BSU10110
symbol: pbpF
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2C required for spore germination; Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall; In the N-terminal section; belongs to the glycosyltransferase 51 family.


ensembl_gene_id: BSU10120
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: BSU10130
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX; Belongs to the ferrochelatase family.


ensembl_gene_id: BSU10140
symbol: hemY
gene_biotype: protein_coding
description:
  Protoporphyrinogen IX and coproporphyrinogen III oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. Also oxidizes the pathway intermediate coproporphyrinogen-III.


ensembl_gene_id: BSU10160
symbol: yhgE
gene_biotype: protein_coding
description:
  Putative methyl-accepting protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU10170
symbol: fabHB
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl carrier protein synthase III 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA, determining the biosynthesis of branched-chain of fatty acids instead of straight-chain.


ensembl_gene_id: BSU10180
symbol: yhfC
gene_biotype: protein_coding
description:
  Putative integral membrane protein, putative chaperone; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU10200
symbol: yhfE
gene_biotype: protein_coding
description:
  Putative endoglucanase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU10220
symbol: gltT
gene_biotype: protein_coding
description:
  Proton/sodium-glutamate symport protein; This carrier protein is part of the Na(+)-dependent, binding- protein-independent glutamate-aspartate transport system.


ensembl_gene_id: BSU10240
symbol: yhfI
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU10250
symbol: lplJ
gene_biotype: protein_coding
description:
  Lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate.


ensembl_gene_id: BSU10260
symbol: yhfK
gene_biotype: protein_coding
description:
  Putative epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU10270
symbol: lcfB
gene_biotype: protein_coding
description:
  Long-chain fatty-acid-CoA ligase (degradative); Involved in the degradation of long-chain fatty acids; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU10290
symbol: yhfN
gene_biotype: protein_coding
description:
  Putative membrane metalloprotease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU10300
symbol: aprE
gene_biotype: protein_coding
description:
  Serine alkaline protease (subtilisin E); Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides; Belongs to the peptidase S8 family.


ensembl_gene_id: BSU10320
symbol: yhfP
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.


ensembl_gene_id: BSU10330
symbol: yhfQ
gene_biotype: protein_coding
description:
  Putative iron(III) dicitrate-binding lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the bacterial solute-binding protein 8 family.


ensembl_gene_id: BSU10340
symbol: phoE
gene_biotype: protein_coding
description:
  Phosphatase; Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activity; Belongs to the phosphoglycerate mutase family. GpmB subfamily.


ensembl_gene_id: BSU10350
symbol: yhfS
gene_biotype: protein_coding
description:
  Putative acetyl-CoA C-acetyltransferase; May be involved in fatty acid metabolism; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: BSU10360
symbol: yhfT
gene_biotype: protein_coding
description:
  Putative long-chain fatty-acid-CoA ligase; May be involved in fatty acid metabolism; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU10380
symbol: hemAT
gene_biotype: protein_coding
description:
  Haem-based dioxygen sensor; Heme-containing signal transducer responsible for aerotaxis, the migratory response toward or away from oxygen.


ensembl_gene_id: BSU10390
symbol: yhfW
gene_biotype: protein_coding
description:
  Putative Rieske [2Fe-2S] oxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU10400
symbol: yhxC
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU10420
symbol: comK
gene_biotype: protein_coding
description:
  Competence transcription factor (CTF); A master regulator required for the expression of late competence genes including comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes. Represses transcription of rok. May repress expression of a few genes.


ensembl_gene_id: BSU10450
symbol: yhjB
gene_biotype: protein_coding
description:
  Putative Na+/metabolite cotransporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU10460
symbol: yhjC
gene_biotype: protein_coding
description:
  Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU10500
symbol: yhjG
gene_biotype: protein_coding
description:
  Putative aromatic compound monooxygenase/hydroxylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU10520
symbol: glcP
gene_biotype: protein_coding
description:
  glucose/mannose:H+ symporter; Can transport glucose, mannose, 2-deoxyglucose and methyl alpha-glucoside, but not galactose.


ensembl_gene_id: BSU10530
symbol: ntdC
gene_biotype: protein_coding
description:
  Biosynthesis of neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose), dehydrogenase; Involved in the biosynthesis of kanosamine (3-amino-3-deoxy- D-glucose), which is known to have antibiotic and antifungal properties, and to be a precursor of the antibiotic neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose (NTD)). Catalyzes the oxidation of glucose 6-phosphate to 3-oxo-D-glucose 6-phosphate. It can only use NAD.


ensembl_gene_id: BSU10540
symbol: ntdB
gene_biotype: protein_coding
description:
  Biosynthesis of neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha, beta-trehalose);hydrolase; Involved in the biosynthesis of kanosamine (3-amino-3-deoxy- D-glucose), which is known to have antibiotic and antifungal properties, and to be a precursor of the antibiotic neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose (NTD)). Catalyzes the dephosphorylation of kanosamine 6-phosphate to yield kanosamine. There is a trace amount of activity using glucosamine-6-phosphate. Belongs to the HAD-like hydrolase superfamily. Cof family.


ensembl_gene_id: BSU10550
symbol: ntdA
gene_biotype: protein_coding
description:
  3-oxo-glucose-6-phosphate:glutamate aminotransferase; Involved in the biosynthesis of kanosamine (3-amino-3-deoxy- D-glucose), which is known to have antibiotic and antifungal properties, and to be a precursor of the antibiotic neotrehalosadiamine (3,3'-diamino-3,3'-dideoxy-alpha,beta-trehalose (NTD)). Catalyzes the reversible pyridoxal phosphate-dependent transamination of 3-dehydro- alpha-D-glucose 6-phosphate to form alpha-D-kanosamine-6-phosphate. It can only use alpha-anomer and glutamate is the only amino donor.


ensembl_gene_id: BSU10560
symbol: yhjM
gene_biotype: protein_coding
description:
  Transcriptional regulator of the ntd operon; Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription.


ensembl_gene_id: BSU10580
symbol: yhjO
gene_biotype: protein_coding
description:
  Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU10590
symbol: yhjP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; In the C-terminal section; belongs to the bacterial solute- binding protein 5 family.


ensembl_gene_id: BSU10600
symbol: yhjQ
gene_biotype: protein_coding
description:
  Putative ferredoxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: putative carrier.


ensembl_gene_id: BSU10610
symbol: yhjR
gene_biotype: protein_coding
description:
  Putative electron carrier protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: putative carrier.


ensembl_gene_id: BSU10620
symbol: addB
gene_biotype: protein_coding
description:
  ATP-dependent deoxyribonuclease (subunit B); The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent single-stranded exonuclease, acting in both directions. Recognizes the B.subtilis chi site (5'-AGCGG-3') which transforms the enzyme from a helicase which degrades both DNA strands to one with only 5' to 3' exonuclease activity. This generates a double-stranded DNA with a protruding 3'-terminated single-stranded tail suitable for the initiation of homologous recombination (chi fragment). The AddB nuclease domain is not required for chi fragment generation; this s [...]


ensembl_gene_id: BSU10630
symbol: addA
gene_biotype: protein_coding
description:
  ATP-dependent deoxyribonuclease (subunit A); An essential component of the DNA double-stranded break repair machinery, the heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the B.subtilis chi site (5'-AGCGG-3') which transforms the enzyme from a helicase which degrades both DNA strands to one with only 5' -> 3' exonuclease activity. This generates a double-stranded DNA with a protruding 3'-terminated single-stranded tail suitable for the initiation of homologous recombination (chi fragment). The AddA nucl [...]


ensembl_gene_id: BSU10640
symbol: sbcD
gene_biotype: protein_coding
description:
  DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity); Belongs to the SbcD family.


ensembl_gene_id: BSU10650
symbol: sbcC
gene_biotype: protein_coding
description:
  DNA ATP-dependent repair enzyme; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity); Belongs to the SMC family. SbcC subfamily.


ensembl_gene_id: BSU10660
symbol: yisB
gene_biotype: protein_coding
description:
  Putative nuclease component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU10670
symbol: gerPF
gene_biotype: protein_coding
description:
  Spore germination protein; Required for the formation of functionally normal spores. Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor.


ensembl_gene_id: BSU10730
symbol: yisI
gene_biotype: protein_coding
description:
  Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family.


ensembl_gene_id: BSU10740
symbol: yisJ
gene_biotype: protein_coding
description:
  Putative spore coat protein; Involved in the assembly of several proteins in the inner and outer layer of the spore coat; Belongs to the CotH family.


ensembl_gene_id: BSU10750
symbol: yisK
gene_biotype: protein_coding
description:
  Putative catabolic enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU10770
symbol: wprA
gene_biotype: protein_coding
description:
  Cell wall-associated protease; CWBP52 is a serine-type protease that could be involved in proteoglycan peptide bridges; Belongs to the peptidase S8 family.


ensembl_gene_id: BSU10800
symbol: yizA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DinB family.


ensembl_gene_id: BSU10810
symbol: yisP
gene_biotype: protein_coding
description:
  Putative squalene/phytoene synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the phytoene/squalene synthase family.


ensembl_gene_id: BSU10820
symbol: yisQ
gene_biotype: protein_coding
description:
  Putative Na+driven efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU10840
symbol: degA
gene_biotype: protein_coding
description:
  Transcriptional regulator (LacI family); Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease.


ensembl_gene_id: BSU10850
symbol: yisS
gene_biotype: protein_coding
description:
  Putative myo-inositol 2-dehydrogenase; Catalyzes the reversible NAD(+)-dependent oxidation of scyllo-inositol (SI) to 2,4,6/3,5-pentahydroxycyclohexanone (scyllo- inosose or SIS). Is required for SI catabolism that allows B.subtilis to utilize SI as the sole carbon source for growth. Cannot use NADP(+) instead of NAD(+); Belongs to the Gfo/Idh/MocA family.


ensembl_gene_id: BSU10870
symbol: yisU
gene_biotype: protein_coding
description:
  Putative aminoacid related metabolite efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU10920
symbol: yitA
gene_biotype: protein_coding
description:
  Putative sulfate adenylyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the sulfate adenylyltransferase family.


ensembl_gene_id: BSU10930
symbol: yitB
gene_biotype: protein_coding
description:
  Putative phospho-adenylylsulfate sulfotransferase; Reduction of activated sulfate into sulfite; Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: BSU10940
symbol: slpH
gene_biotype: protein_coding
description:
  2-phosphosulfolactate phosphatase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the ComB family.


ensembl_gene_id: BSU10950
symbol: slpS
gene_biotype: protein_coding
description:
  Phosphosulfolactate synthase; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL) (By similarity). Is probably involved in the biosynthesis of L-sulfolactate, which is a major constituent of sporulating cells and mature spores. Belongs to the phosphosulfolactate synthase family.


ensembl_gene_id: BSU10970
symbol: yitF
gene_biotype: protein_coding
description:
  Putative enolase superfamily enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: BSU11010
symbol: samT
gene_biotype: protein_coding
description:
  Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU11020
symbol: yitK
gene_biotype: protein_coding
description:
  Putative RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UPF0234 family.


ensembl_gene_id: BSU11030
symbol: yitL
gene_biotype: protein_coding
description:
  RNA-binding protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.


ensembl_gene_id: BSU11055
symbol: yitO
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein with HTTM domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU11070
symbol: yitP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 6289325.


ensembl_gene_id: BSU11079
symbol: yizB
gene_biotype: protein_coding
description:
  Putative DNA/RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU11100
symbol: nprB
gene_biotype: protein_coding
description:
  Extracellular neutral protease B; Protease able to cleave casein in vitro. Belongs to the peptidase M4 family.


ensembl_gene_id: BSU11110
symbol: yitS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.


ensembl_gene_id: BSU11130
symbol: ipi
gene_biotype: protein_coding
description:
  Intracellular proteinase inhibitor BsuPI; Directly regulates the major intracellular proteinase (ISP-1) activity in vivo. Inhibits ISP-1 in the early stages of sporulation. It may be then inactivated by a membrane-bound proteinase.


ensembl_gene_id: BSU11140
symbol: yitU
gene_biotype: protein_coding
description:
  Putative phosphatase; Catalyzes the dephosphorylation of the riboflavin precursor 5-amino-6-(5-phospho-D-ribitylamino)uracil and of flavin mononucleotide (FMN) in vitro.


ensembl_gene_id: BSU11150
symbol: yitV
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU11160
symbol: yitW
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the maturation of iron-sulfur (Fe-S) proteins. May function as a Fe-S cluster carrier.


ensembl_gene_id: BSU11170
symbol: yitY
gene_biotype: protein_coding
description:
  Putative FMN/FAD-binding oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU11180
symbol: yitZ
gene_biotype: protein_coding
description:
  Putative transport protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU11190
symbol: argC
gene_biotype: protein_coding
description:
  N-acetylglutamate gamma-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: BSU11200
symbol: argJ
gene_biotype: protein_coding
description:
  Ornithine acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.


ensembl_gene_id: BSU11210
symbol: argB
gene_biotype: protein_coding
description:
  N-acetylglutamate 5-phosphotransferase (acetylglutamate kinase); Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: BSU11220
symbol: argD
gene_biotype: protein_coding
description:
  N-acetylornithine aminotransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: BSU11230
symbol: carA
gene_biotype: protein_coding
description:
  Arginine-specific carbamoyl-phosphate synthetase (small subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU11240
symbol: carB
gene_biotype: protein_coding
description:
  Arginine-specific carbamoyl-phosphate synthetase (large subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the CarB family.


ensembl_gene_id: BSU11250
symbol: argF
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.


ensembl_gene_id: BSU11290
symbol: yjaV
gene_biotype: protein_coding
description:
  Putative NAD(P) binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU11300
symbol: med
gene_biotype: protein_coding
description:
  Positive regulator of comK; Positive activator of the comK gene; Belongs to the BMP lipoprotein family.


ensembl_gene_id: BSU11320
symbol: yjzB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16391061.


ensembl_gene_id: BSU11330
symbol: fabHA
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl carrier protein synthase III 1; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for branched chain acyl-CoA, determining the biosynthesis of branched-chain of fatty acids instead of straight-chain.


ensembl_gene_id: BSU11340
symbol: fabF
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl carrier protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: BSU11360
symbol: appD
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (ATP-binding protein); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU11390
symbol: appB
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (oligopeptide-binding lipoprotein); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.


ensembl_gene_id: BSU11400
symbol: appC
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (permease); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.


ensembl_gene_id: BSU11410
symbol: yjbA
gene_biotype: protein_coding
description:
  Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the UPF0736 family.


ensembl_gene_id: BSU11420
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: BSU11430
symbol: oppA
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (binding lipoprotein); This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, It binds peptides up to five amino acids long with high affinity. Also required for sporulation and competence.


ensembl_gene_id: BSU11440
symbol: oppB
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence.


ensembl_gene_id: BSU11460
symbol: oppD
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (ATP-binding protein); Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence.


ensembl_gene_id: BSU11470
symbol: oppF
gene_biotype: protein_coding
description:
  Oligopeptide ABC transporter (ATP-binding protein); Component of the oligopeptide permease, a binding protein- dependent transport system. Necessary for genetic competence but not sporulation. Probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU11490
symbol: yjbC
gene_biotype: protein_coding
description:
  Putative thiol oxidation management factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU11500
symbol: spxA
gene_biotype: protein_coding
description:
  Redox-sensitive regulator enzyme; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Negatively affects competence and sporulation. Its degradation by the MecA/ClpXP complex is needed for competence development; Belongs to the ArsC family. Spx subfamily.


ensembl_gene_id: BSU11510
symbol: yjbE
gene_biotype: protein_coding
description:
  Putative transporter component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU11520
symbol: mecA
gene_biotype: protein_coding
description:
  Adaptor protein controlling oligomerization of the AAA+ protein ClpC; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.


ensembl_gene_id: BSU11530
symbol: coiA
gene_biotype: protein_coding
description:
  Protein involved in establishment of DNA transport in competence; Required for optimal transformation.


ensembl_gene_id: BSU11550
symbol: yjbH
gene_biotype: protein_coding
description:
  Putative thiol management oxidoreductase component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU11560
symbol: yjbI
gene_biotype: protein_coding
description:
  Putative thiol management oxidoreductase component; Hemoglobin-like protein that exhibits a low peroxidase activity. Its very high oxygen affinity may rule out the possibility that it is involved in oxygen transport.


ensembl_gene_id: BSU11570
symbol: yjbJ
gene_biotype: protein_coding
description:
  Putative murein lytic transglycosylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the transglycosylase Slt family.


ensembl_gene_id: BSU11580
symbol: yjbK
gene_biotype: protein_coding
description:
  Putative RNA/thiamine triphosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU11590
symbol: yjbL
gene_biotype: protein_coding
description:
  Putative phosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the UPF0738 family.


ensembl_gene_id: BSU11600
symbol: relP
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase; Functions as a (p)ppGpp synthase; GDP can be used instead of GTP, resulting in an increase of (p)ppGpp synthesis. The enzyme binds ATP, then GDP or GTP and catalysis is highly cooperative. In eubacteria ppGpp (guanosine 3'- diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. Probably has a minor role in the stringent response ; Belongs to the RelA/SpoT family.


ensembl_gene_id: BSU11610
symbol: ppnKA
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates (GTP, UTP) as well as inorganic polyphosphate (poly(P)) as a source of phosphorus.


ensembl_gene_id: BSU11620
symbol: yjbO
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.


ensembl_gene_id: BSU11630
symbol: prpE
gene_biotype: protein_coding
description:
  Phosphorylated protein phosphatase E and diadenosine-polyphosphate hydrolase; Asymmetrically hydrolyzes Ap4p to yield AMP and ATP. Does not hydrolyze Ap2a or Ap6A. Also has an ATPase activity. Was shown to dephosphorylate phosphotyrosine but not phosphoserine or phosphothreonine from phosphorylated peptides. Involved in spore germination by controlling expression of genes coding for GerA and GerK receptors.


ensembl_gene_id: BSU11640
symbol: yjbQ
gene_biotype: protein_coding
description:
  Putative Na+/H+ antiporter; Probable Na(+)/H(+) antiporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: BSU11650
symbol: tenA
gene_biotype: protein_coding
description:
  Thiaminase II; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP). To a lesser extent, is also able to catalyze the hydrolytic cleavage of thiamine; however, this thiaminase activity is unlikely to be physiologically relevant. Therefore, is involved in the regeneration of the thiamine pyrimidine from thiamine degraded products present in the enviro [...]


ensembl_gene_id: BSU11660
symbol: tenI
gene_biotype: protein_coding
description:
  Thiazole tautomerase; Catalyzes the irreversible aromatization of 2-((2R,5Z)-2- carboxy-4-methylthiazol-5(2H)-ylidene)ethyl phosphate (cThz*-P) to 2- (2-carboxy-4-methylthiazol-5-yl)ethyl phosphate (cThz-P), a step in the biosynthesis of the thiazole phosphate moiety of thiamine. Cannot use cThz* as substrate, indicating that the phosphate group is essential. Has no thiamine phosphate synthase activity, despite a high sequence similarity with ThiE.


ensembl_gene_id: BSU11670
symbol: thiO
gene_biotype: protein_coding
description:
  FAD-dependent glycine oxidase; Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha-keto acids, ammonia/amine, and hydrogen peroxide. Oxidizes sarcosine (N- methylglycine), N-ethylglycine and glycine. Can also oxidize the herbicide glyphosate (N-phosphonomethylglycine). Displays lower activities on D-alanine, D-valine, D-proline and D-methionine. Does not act on L-amino acids and other D-amino acids. Is essential for thiamine biosynthesis since the oxidation of glycine catalyzed by ThiO generates the glycine imine interm [...]


ensembl_gene_id: BSU11680
symbol: thiS
gene_biotype: protein_coding
description:
  Sulfur carrier for synthesis of hydroxyethylthiazole phosphate; Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate; Belongs to the sulfur carrier protein ThiS family.


ensembl_gene_id: BSU11690
symbol: thiG
gene_biotype: protein_coding
description:
  Hydroxyethylthiazole phosphate synthetase (thiamine biosynthesis); Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: BSU11700
symbol: thiF
gene_biotype: protein_coding
description:
  Adenylate transferase and sulfur transferase (thiamine biosynthesis); Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS; Belongs to the HesA/MoeB/ThiF family.


ensembl_gene_id: BSU11710
symbol: thiD
gene_biotype: protein_coding
description:
  Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. Shows no activity with pyridoxal, pyridoxamine or pyridoxine.


ensembl_gene_id: BSU11720
symbol: fabI
gene_biotype: protein_coding
description:
  Enoyl-acyl carrier protein reductase; Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism.


ensembl_gene_id: BSU11730
symbol: cotO
gene_biotype: protein_coding
description:
  Spore outer coat protein; Has an important morphogenetic role. Involved in the assembly of at least five coat proteins, including CotB, CotG, CotS, CotSA and CotW. Required for appearance of a morphologically normal outer coat. To a large degree, CotO and CotH act at a late stage of coat assembly from within the outer coat to direct maturation of this structure.


ensembl_gene_id: BSU11740
symbol: cotZ
gene_biotype: protein_coding
description:
  Spore coat protein (insoluble fraction, outermost layer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.


ensembl_gene_id: BSU11750
symbol: cotY
gene_biotype: protein_coding
description:
  Outer spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU11760
symbol: cotX
gene_biotype: protein_coding
description:
  Spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU11809
symbol: yjcZ
gene_biotype: protein_coding
description:
  Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU11810
symbol: spoVIF
gene_biotype: protein_coding
description:
  Sporulation-specific protein needed for heat resistance; Transcription factor involved in spore coat assembly and spore resistance. Regulates the transcription of at least cgeA, cotG and cotS.


ensembl_gene_id: BSU11820
symbol: yjcD
gene_biotype: protein_coding
description:
  Putative ATP-dependent DNA helicase; May be involved in the generation of recombinogenic substrates for the subsequent action of RecA.


ensembl_gene_id: BSU11839
symbol: yjzE
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 11976315.


ensembl_gene_id: BSU11850
symbol: yjcG
gene_biotype: protein_coding
description:
  Putative RNA ligase or phosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU11870
symbol: metI
gene_biotype: protein_coding
description:
  Cystathionine gamma-synthase and O-acetylhomoserine thiolyase; Catalyzes the formation of L-cystathionine from O-acetyl-L- homoserine and L-cysteine. Cannot use O-succinyl-L-homoserine as substrate. Also exhibits O-acetylhomoserine thiolyase activity, catalyzing the synthesis of L-homocysteine from O-acetyl-L-homoserine and sulfide.


ensembl_gene_id: BSU11880
symbol: metC
gene_biotype: protein_coding
description:
  Cystathionine beta-lyase; Catalyzes the transformation of cystathionine into homocysteine. Also exhibits cysteine desulfhydrase activity in vitro, producing sulfide from cysteine; Belongs to the trans-sulfuration enzymes family.


ensembl_gene_id: BSU11890
symbol: yjcK
gene_biotype: protein_coding
description:
  Putative ribosomal-protein-alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S5.


ensembl_gene_id: BSU11930
symbol: yjcO
gene_biotype: protein_coding
description:
  Putative DNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU11940
symbol: yjcP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535.


ensembl_gene_id: BSU11960
symbol: yjcR
gene_biotype: protein_coding
description:
  Putative phage-related nucleic acid binding terminase small subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU11980
symbol: yjdA
gene_biotype: protein_coding
description:
  Putative acyl-carrier protein oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU11990
symbol: yjdB
gene_biotype: protein_coding
description:
  Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU12000
symbol: manR
gene_biotype: protein_coding
description:
  Transcriptional antiterminator; Positively regulates the expression of the mannose operon that consists of three genes, manP, manA, and yjdF, which are responsible for the transport and utilization of mannose. Also activates its own expression.


ensembl_gene_id: BSU12010
symbol: manP
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) mannose-specific enzyme IIBCA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannose transport.


ensembl_gene_id: BSU12020
symbol: manA
gene_biotype: protein_coding
description:
  Mannose-6 phosphate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family.


ensembl_gene_id: BSU12030
symbol: yjdF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 20139185.


ensembl_gene_id: BSU12060
symbol: trnE
gene_biotype: protein_coding
description:
  tRNA editing protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.


ensembl_gene_id: BSU12080
symbol: ctaO
gene_biotype: protein_coding
description:
  Minor protoheme IX farnesyltransferase 1 (heme O synthase); Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: BSU12090
symbol: cotT
gene_biotype: protein_coding
description:
  Spore coat protein (inner coat); Inner spore coat protein which seems to play a role in germination.


ensembl_gene_id: BSU12100
symbol: pdaC
gene_biotype: protein_coding
description:
  N-acetylmuramic acid deacetylase; Catalyzes the deacetylation of N-acetylmuramic acid (MurNAc) residues in peptidoglycan, a modification that confers resistance to lysosyme. Is not able to deacetylate N-acetylglucosamine (GlcNAc) residues in peptidoglycan, but can deacylate chitin oligomers such as GlcNAc4 and GlcNAc5. Is essentially not active toward chitosan (partially deacetylated GlcNAc polymer) and has very low activity toward chitin (GlcNAc polymer). Does not deacetylate GlcNAc. In the N-terminal section; belongs to the RsiV family.


ensembl_gene_id: BSU12140
symbol: yjgA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406.


ensembl_gene_id: BSU12150
symbol: yjgB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1580552.


ensembl_gene_id: BSU12160
symbol: yjgC
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU12190
symbol: yjhB
gene_biotype: protein_coding
description:
  Putative ADP-ribose pyrophosphatase; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.


ensembl_gene_id: BSU12210
symbol: yjiB
gene_biotype: protein_coding
description:
  Putative monooxygenase (cytochrome P450); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU12250
symbol: yjkB
gene_biotype: protein_coding
description:
  Putative phosphate ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU12270
symbol: yjlB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10704478.


ensembl_gene_id: BSU12280
symbol: yjlC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17015645.


ensembl_gene_id: BSU12290
symbol: ndh
gene_biotype: protein_coding
description:
  NADH dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the NADH dehydrogenase family.


ensembl_gene_id: BSU12300
symbol: uxaC
gene_biotype: protein_coding
description:
  Galacturonate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU12310
symbol: exuM
gene_biotype: protein_coding
description:
  Putative Na+:altronate/mannonate symporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t: transporter.


ensembl_gene_id: BSU12340
symbol: uxuA
gene_biotype: protein_coding
description:
  D-mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.


ensembl_gene_id: BSU12350
symbol: uxuB
gene_biotype: protein_coding
description:
  Fructuronate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU12360
symbol: exuT
gene_biotype: protein_coding
description:
  Hexuronate transporter; Aldohexuronate transport system; Belongs to the major facilitator superfamily. Phthalate permease family.


ensembl_gene_id: BSU12370
symbol: exuR
gene_biotype: protein_coding
description:
  Transcriptional regulator (LacI family); Transcriptional repressor for the exu locus which is required for galacturonate utilization.


ensembl_gene_id: BSU12380
symbol: uxaB
gene_biotype: protein_coding
description:
  Tagaturonate reductase (altronate oxidoreductase); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the mannitol dehydrogenase family. UxaB subfamily.


ensembl_gene_id: BSU12430
symbol: rapA
gene_biotype: protein_coding
description:
  Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. Belongs to the RAP family.


ensembl_gene_id: BSU12440
symbol: phrA
gene_biotype: protein_coding
description:
  Secreted inhibitor of the activity of phosphatase RapA; Inhibitor of the activity of phosphatase RapA.


ensembl_gene_id: BSU12450
symbol: yjpA
gene_biotype: protein_coding
description:
  Putative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the YciI family.


ensembl_gene_id: BSU12460
symbol: xlyB
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation.


ensembl_gene_id: BSU12480
symbol: yjqB
gene_biotype: protein_coding
description:
  Putative PBSX phage-related replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; Belongs to the UPF0714 family.


ensembl_gene_id: BSU12490
symbol: yjqC
gene_biotype: protein_coding
description:
  Putative PBSX phage manganese-containing catalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; Belongs to the manganese catalase family.


ensembl_gene_id: BSU12500
symbol: xkdA
gene_biotype: protein_coding
description:
  PBSX phage protein, putative peptidase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; To B.subtilis YqaB.


ensembl_gene_id: BSU12510
symbol: xre
gene_biotype: protein_coding
description:
  Phage PBSX transcriptional regulator; Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state.


ensembl_gene_id: BSU12520
symbol: xkdB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqaL.


ensembl_gene_id: BSU12530
symbol: xkdC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein in PBSX phage element; May function as a transcriptional antiterminator.


ensembl_gene_id: BSU12550
symbol: xtrA
gene_biotype: protein_coding
description:
  PBSX phage protein, homolog of YqaO of the skin element; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; To B.subtilis YqaO.


ensembl_gene_id: BSU12560
symbol: xpf
gene_biotype: protein_coding
description:
  Putative RNA polymerase PBSX sigma factor-like; Positive regulatory protein that acts at the late promoter PL.


ensembl_gene_id: BSU12570
symbol: xtmA
gene_biotype: protein_coding
description:
  PBSX defective prophage terminase (small subunit); Functions as a terminase; To B.subtilis YqaS and B.subtilis phage SPP1 terminase small subunit.


ensembl_gene_id: BSU12580
symbol: xtmB
gene_biotype: protein_coding
description:
  PBSX defective prophage terminase (large subunit); Functions as a terminase; To B.subtilis YqaT and phage SPP1 terminase large subunit.


ensembl_gene_id: BSU12590
symbol: xkdE
gene_biotype: protein_coding
description:
  Putative phage capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure; Belongs to the phage portal family. PBSX subfamily.


ensembl_gene_id: BSU12600
symbol: xkdF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbD.


ensembl_gene_id: BSU12610
symbol: xkdG
gene_biotype: protein_coding
description:
  Putative capsid protein of PBSX prophage; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.


ensembl_gene_id: BSU12620
symbol: xkdH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbH.


ensembl_gene_id: BSU12630
symbol: xkdI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbI.


ensembl_gene_id: BSU12640
symbol: xkdJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbJ.


ensembl_gene_id: BSU12649
symbol: ykzM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein from phage origin; Evidence 4: Homologs of previously reported genes of unknown function.


ensembl_gene_id: BSU12650
symbol: xkdK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein in phage element PBSX; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the myoviridae tail sheath protein family.


ensembl_gene_id: BSU12660
symbol: xkdM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbM.


ensembl_gene_id: BSU12671
symbol: xkdN
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbN.


ensembl_gene_id: BSU12680
symbol: xkdO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbO.


ensembl_gene_id: BSU12690
symbol: xkdP
gene_biotype: protein_coding
description:
  Putative PBSX prophage murein binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU12700
symbol: xkdQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbQ.


ensembl_gene_id: BSU12710
symbol: xkdR
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbR.


ensembl_gene_id: BSU12720
symbol: xkdS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqbS.


ensembl_gene_id: BSU12730
symbol: xkdT
gene_biotype: protein_coding
description:
  Putative base plate assembly protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the Mu gp47/PBSX XkdT family.


ensembl_gene_id: BSU12740
symbol: xkdU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqcA.


ensembl_gene_id: BSU12750
symbol: xkdV
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqcC.


ensembl_gene_id: BSU12770
symbol: xkdX
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YqcE.


ensembl_gene_id: BSU12780
symbol: xepA
gene_biotype: protein_coding
description:
  Lytic exoenzyme associated with defective prophage PBSX; Not known; does not seem to be involved in host cell lysis.


ensembl_gene_id: BSU12790
symbol: xhlA
gene_biotype: protein_coding
description:
  Defective prophage PBSX putative enzyme; Associated with cell lysis upon induction of PbsX; To B.licheniformis xpaF1 and xpaL1.


ensembl_gene_id: BSU12800
symbol: xhlB
gene_biotype: protein_coding
description:
  Bacteriophage PBSX holin; Involved in cell lysis upon induction of PbsX; Belongs to the SPP1 holin family.


ensembl_gene_id: BSU12810
symbol: xlyA
gene_biotype: protein_coding
description:
  Bacteriophage PBSX N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation.


ensembl_gene_id: BSU12820
symbol: spoIISB
gene_biotype: protein_coding
description:
  Two-component apoptotic control system component B (antitoxin); Antitoxin component of a type II toxin-antitoxin (TA) system. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activity; unlike most antitoxins it does not seem to be highly labile upon expression in E.coli.


ensembl_gene_id: BSU12830
symbol: spoIISA
gene_biotype: protein_coding
description:
  Two-component apoptosis factor (toxin/antitoxin system); Toxic component of a type II toxin-antitoxin (TA) system. Its toxic activity is neutralized by cognate antitoxin SpoIISB. Expression in the absence of SpoIISB permits sporulation to stage II, when plasmolysis zones and holes in the peptidoglycan layer are observed, resulting in cell death. Lethal when synthesized during vegetative growth in the absence of SpoIISB. In E.coli both the membrane bound and soluble domain are required in cis for toxin activity.


ensembl_gene_id: BSU12840
symbol: pit
gene_biotype: protein_coding
description:
  Low-affinity inorganic phosphate transporter; Low-affinity inorganic phosphate transport; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily.


ensembl_gene_id: BSU12850
symbol: ykaA
gene_biotype: protein_coding
description:
  Putative Pit accessory protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the UPF0111 family.


ensembl_gene_id: BSU12860
symbol: ykbA
gene_biotype: protein_coding
description:
  Putative amino acid permease; Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids.


ensembl_gene_id: BSU12870
symbol: mhqA
gene_biotype: protein_coding
description:
  Putative hydroquinone-specific extradiol dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds.


ensembl_gene_id: BSU12900
symbol: htrA
gene_biotype: protein_coding
description:
  Membrane bound serine protease Do, quality control protease (heat-shock protein); Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family.


ensembl_gene_id: BSU12910
symbol: proG
gene_biotype: protein_coding
description:
  Redundant pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: BSU12920
symbol: dppA
gene_biotype: protein_coding
description:
  D-alanyl-aminopeptidase; Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear; Belongs to the peptidase M55 family.


ensembl_gene_id: BSU12930
symbol: dppB
gene_biotype: protein_coding
description:
  Dipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions.


ensembl_gene_id: BSU12940
symbol: dppC
gene_biotype: protein_coding
description:
  Dipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation.


ensembl_gene_id: BSU12950
symbol: dppD
gene_biotype: protein_coding
description:
  Dipeptide ABC transporter (ATP-binding protein); Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. Expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU12960
symbol: dppE
gene_biotype: protein_coding
description:
  Dipeptide ABC transporter (dipeptide-binding lipoprotein); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation; Belongs to the bacterial solute-binding protein 5 family.


ensembl_gene_id: BSU12970
symbol: ldcA
gene_biotype: protein_coding
description:
  Muropeptide L,D-carboxypeptidase; May be involved in the degradation of peptidoglycan by catalyzing the cleavage of the terminal D-alanine residue from cytoplasmic murein peptides; Belongs to the peptidase S66 family.


ensembl_gene_id: BSU12980
symbol: ykfB
gene_biotype: protein_coding
description:
  L-Ala-D/L-Glu epimerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the reverse reaction and the epimerization of the other Ala-X dipeptides L-Ala-L- Asp, L-Ala-L-Leu, L-Ala-L-Met, and L-Ala-L-Ser. Is not able to epimerize other L-Ala-X dipeptides. Is also active with L-Ser-L-Glu and, oddly, L-Pro-L-Glu, but not with L-Glu-L-Glu, L-Lys-L-Glu, L-Lys- L-Ala, or D-Ala-D-Ala.


ensembl_gene_id: BSU12990
symbol: ykfC
gene_biotype: protein_coding
description:
  gamma-D-glutamyl-L-diaminoacid endopeptidase; Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides, releasing L-Ala-D-Glu.


ensembl_gene_id: BSU13000
symbol: ykfD
gene_biotype: protein_coding
description:
  Putative cell wall oligopeptide ABC transporter (ATP binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU13010
symbol: pgl
gene_biotype: protein_coding
description:
  6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.


ensembl_gene_id: BSU13020
symbol: ykgA
gene_biotype: protein_coding
description:
  Putative aminohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the DDAH family.


ensembl_gene_id: BSU13030
symbol: ykhA
gene_biotype: protein_coding
description:
  Putative acyl-CoA hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acyl coenzyme A hydrolase family.


ensembl_gene_id: BSU13040
symbol: hmp
gene_biotype: protein_coding
description:
  Flavohemoglobin; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: BSU13080
symbol: ykkB
gene_biotype: protein_coding
description:
  Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU13090
symbol: ykkC
gene_biotype: protein_coding
description:
  Efflux transporter; Probably involved in guanidinium transport. In vitro, confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials.


ensembl_gene_id: BSU13110
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: BSU13120
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: BSU13130
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: BSU13150
symbol: ohrR
gene_biotype: protein_coding
description:
  Transcriptional regulator sensing organic peroxides; Organic peroxide sensor. Represses the expression of the peroxide-inducible gene ohrA by cooperative binding to two inverted repeat elements.


ensembl_gene_id: BSU13160
symbol: ohrB
gene_biotype: protein_coding
description:
  Organic hydroperoxide resistance reductase B; Involved in organic hydroperoxide resistance. Belongs to the OsmC/Ohr family.


ensembl_gene_id: BSU13180
symbol: metE
gene_biotype: protein_coding
description:
  Cobalamin-independent methionine synthase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation.


ensembl_gene_id: BSU13200
symbol: rsbRB
gene_biotype: protein_coding
description:
  Component of the piezosome (stressosome); One of 4 functionally non-identical RsbR paralogs, it functions in the environmental signaling branch of the general stress response.


ensembl_gene_id: BSU13210
symbol: thiX
gene_biotype: protein_coding
description:
  Thiamine transporter, permease component; Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable).


ensembl_gene_id: BSU13220
symbol: thiW
gene_biotype: protein_coding
description:
  Thiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable).


ensembl_gene_id: BSU13240
symbol: thiU
gene_biotype: protein_coding
description:
  Thiamine binding protein; Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Binds thiamine via its HMP moiety.


ensembl_gene_id: BSU13250
symbol: ykoG
gene_biotype: protein_coding
description:
  Two-component response regulator [YkoH]; Probable member of the two-component regulatory system YkoH/YkoG.


ensembl_gene_id: BSU13260
symbol: ykoH
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YkoG]; Probable member of the two-component regulatory system YkoH/YkoG. Potentially phosphorylates YkoG.


ensembl_gene_id: BSU13280
symbol: ykoJ
gene_biotype: protein_coding
description:
  Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype.


ensembl_gene_id: BSU13310
symbol: tnrA
gene_biotype: protein_coding
description:
  Nitrogen sensing transcriptional regulator; Transcription regulator that actives the transcription of genes required for nitrogen assimilation such as nrgAB (ammonium transport), nasABCDEF (nitrate/nitrite assimilation), ureABC (urea degradation) and gabP (GABA transport), during nitrogen limitation. Also represses glnRA and gltAB in the absence of ammonium. On the contrary of the MerR members, which require longer DNA sites for high-affinity binding, TnrA requires a DNA sequence of 17 nucleotides as minimal binding site.


ensembl_gene_id: BSU13320
symbol: ykzB
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441.


ensembl_gene_id: BSU13350
symbol: ykoN
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase 28 family.


ensembl_gene_id: BSU13370
symbol: ykoQ
gene_biotype: protein_coding
description:
  Putative metallophosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU13390
symbol: ykoT
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase 2 family.


ensembl_gene_id: BSU13400
symbol: ykoU
gene_biotype: protein_coding
description:
  ATP-dependent DNA ligase subunit; With Ku forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity (Probable). Probably involved in DNA repair during spore germination. In the N-terminal section; belongs to the LigD polymerase family.


ensembl_gene_id: BSU13410
symbol: ykoV
gene_biotype: protein_coding
description:
  ATP-dependent DNA ligase subunit; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (By similarity). Probably involved in DNA repair during spore germination. Belongs to the prokaryotic Ku family.


ensembl_gene_id: BSU13420
symbol: ykoW
gene_biotype: protein_coding
description:
  Putative sensor diguanylate cyclase; Probable signaling protein whose physiological role is not yet known.


ensembl_gene_id: BSU13450
symbol: sigI
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of cell wall metabolism in response to heat stress. Acts by regulating the expression of genes such as bcrC, mreBH and lytE. Also plays a role in survival at low temperatures. Belongs to the sigma-70 factor family. SigI subfamily.


ensembl_gene_id: BSU13460
symbol: rsgI
gene_biotype: protein_coding
description:
  sigmaI modulating factor; Anti-sigma factor for SigI. Negatively regulates SigI activity through direct interaction.


ensembl_gene_id: BSU13470
symbol: sspD
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein (alpha/beta-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.


ensembl_gene_id: BSU13480
symbol: htpK
gene_biotype: protein_coding
description:
  Regulator of quality control; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU13490
symbol: htpX
gene_biotype: protein_coding
description:
  Membrane protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the peptidase M48B family.


ensembl_gene_id: BSU13500
symbol: ktrD
gene_biotype: protein_coding
description:
  K+-transporting ATPase; Integral membrane subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress; Belongs to the TrkH potassium transport family. Ktr (TC 2.A.38.4) subfamily.


ensembl_gene_id: BSU13520
symbol: ykrP
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU13530
symbol: kinE
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F.


ensembl_gene_id: BSU13540
symbol: ogt
gene_biotype: protein_coding
description:
  O6-alkylguanine DNA alkyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: BSU13550
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase (methionine salvage pathway); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).


ensembl_gene_id: BSU13560
symbol: mtnK
gene_biotype: protein_coding
description:
  Methylthioribose kinase (methionine salvage pathway); Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.


ensembl_gene_id: BSU13570
symbol: mtnU
gene_biotype: protein_coding
description:
  Ketoglutaramate omega-amidase; May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway; Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.


ensembl_gene_id: BSU13580
symbol: mtnE
gene_biotype: protein_coding
description:
  Methionine-glutamine aminotransferase; Catalyzes the formation of methionine from 2-keto-4- methylthiobutyrate (KMTB).


ensembl_gene_id: BSU13590
symbol: mtnW
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthiopentyl-1-phosphate enolase (DK-MTP-1-P enolase); Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily.


ensembl_gene_id: BSU13600
symbol: mtnX
gene_biotype: protein_coding
description:
  2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphatephosphatase (HK-MTPenyl-1-P phosphatase); Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene).


ensembl_gene_id: BSU13610
symbol: mtnB
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase); Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: BSU13620
symbol: mtnD
gene_biotype: protein_coding
description:
  Acireductone dioxygenase (Ni2+ or Fe2+-requiring); Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.


ensembl_gene_id: BSU13640
symbol: spo0E
gene_biotype: protein_coding
description:
  Negative regulatory phosphatase acting on Spo0A-P (sporulation); Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family.


ensembl_gene_id: BSU13650
symbol: eag
gene_biotype: protein_coding
description:
  Putative small membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU13660
symbol: kinD
gene_biotype: protein_coding
description:
  Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions.


ensembl_gene_id: BSU13670
symbol: mhqR
gene_biotype: protein_coding
description:
  Transcriptional regulator (MarR family); Negatively regulates mhqA, mhqED, mhqNOP, and azoR2 which may contribute to the degradation of aromatic compounds.


ensembl_gene_id: BSU13680
symbol: motB
gene_biotype: protein_coding
description:
  Motility protein B; MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity).


ensembl_gene_id: BSU13690
symbol: motA
gene_biotype: protein_coding
description:
  Motility protein A; MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel (By similarity).


ensembl_gene_id: BSU13700
symbol: clpE
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease (class III stress gene); ATPase essential both for efficient CtsR-dependent gene derepression during heat stress and for rerepression. Together with ClpP, degrades the global regulator CtsR after heat shock. Is also involved in disaggregation of heat-denatured proteins. Has thus a role in overall protein quality control in response to heat stress.


ensembl_gene_id: BSU13720
symbol: queC
gene_biotype: protein_coding
description:
  Pre-queuosine 0 synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Uses ammonia as nitrogen donor.


ensembl_gene_id: BSU13730
symbol: queD
gene_biotype: protein_coding
description:
  6-carboxy-5,6,7,8-tetrahydropterin synthase; Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Belongs to the PTPS family. QueD subfamily.


ensembl_gene_id: BSU13740
symbol: queE
gene_biotype: protein_coding
description:
  7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: BSU13750
symbol: queF
gene_biotype: protein_coding
description:
  NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine pathway; Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: BSU13770
symbol: ykvO
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU13780
symbol: ykvP
gene_biotype: protein_coding
description:
  Spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU13789
symbol: ykzQ
gene_biotype: protein_coding
description:
  Putative peptidoglycan binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU13790
symbol: ykvQ
gene_biotype: protein_coding
description:
  Putative sporulation-specific glycosylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: BSU13799
symbol: ykzR
gene_biotype: protein_coding
description:
  Putative spore-specific glycosyl hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: BSU13820
symbol: ykvT
gene_biotype: protein_coding
description:
  Cell wall hydrolase related to spore cortex-lytic enzymes; Evidence 2b: Function of strongly homologous gene; enzyme.


ensembl_gene_id: BSU13830
symbol: ykvU
gene_biotype: protein_coding
description:
  Spore membrane protein involved in germination; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.


ensembl_gene_id: BSU13840
symbol: stoA
gene_biotype: protein_coding
description:
  Thiol-disulfide isomerase; Thiol-disulfide oxidoreductase with a reductive function, involved in spore cortex synthesis. It could be involved either in breaking disulfide bonds in cortex components or in proteins that are important for cortex synthesis, or in thiol/disulfide bond interchange. Belongs to the thioredoxin family.


ensembl_gene_id: BSU13850
symbol: zosA
gene_biotype: protein_coding
description:
  Zn transporter; Couples the hydrolysis of ATP with the transport of zinc into the cell. Plays an important role in protecting cells against oxidative stress. ZosA-mediated zinc transport is required for post- transcriptional control of comK and competence development.


ensembl_gene_id: BSU13860
symbol: ykvY
gene_biotype: protein_coding
description:
  Putative Xaa-Pro dipeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU13870
symbol: ykvZ
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (LacI family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU13880
symbol: glcT
gene_biotype: protein_coding
description:
  Transcriptional antiterminator (BglG family); Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of GlcT directly binds to the RNA antiterminator (RAT) sequence and prevents transcriptional termination. GlcT binding requires two identical and nearly symmetrical triple base pairings in the RAT sequence.


ensembl_gene_id: BSU13890
symbol: ptsG
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) glucose-specific enzyme IICBA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.


ensembl_gene_id: BSU13900
symbol: ptsH
gene_biotype: protein_coding
description:
  Histidine-containing phosphocarrier protein of the phosphotransferase system (PTS) (HPr protein); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.


ensembl_gene_id: BSU13910
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: BSU13930
symbol: splB
gene_biotype: protein_coding
description:
  Spore photoproduct (thymine dimer) lyase; Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5,6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines.


ensembl_gene_id: BSU13950
symbol: mcpC
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. All amino acids serve as attractants in B.subtilis, they appear to cause an increase in the turnover methyl groups, leading to methylation of an unidentified acceptor, while repellents have been shown to cause a decrease in methyl group turnover. The methyl groups are added by a methyl [...]


ensembl_gene_id: BSU13980
symbol: pbpH
gene_biotype: protein_coding
description:
  Penicillin-binding enzyme for formation of rod-shaped peptidoglycan cell wall; Involved in the polymerization of peptidoglycan. Plays a redundant role with PBP2a in determining the rod shape of the cell during vegetative growth and spore outgrowth. Belongs to the transpeptidase family.


ensembl_gene_id: BSU13990
symbol: kinA
gene_biotype: protein_coding
description:
  Sporulation-specific ATP-dependent protein histidine kinase; Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP.


ensembl_gene_id: BSU14000
symbol: dapX
gene_biotype: protein_coding
description:
  N-acetyl-L,L-diaminopimelate aminotransferase; Essential for murein biosynthesis. Probably catalyzes the conversion of L-2-acetamido-6-oxopimelate to N-acetyl-LL- 2,6-diaminopimelate (Probable); Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU14010
symbol: cheV
gene_biotype: protein_coding
description:
  Coupling protein and response regulator for CheA activity in response to attractants (chemotaxis); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW are involved in the coupling of the methyl- accepting chemoreceptors to the central two-component kinase CheA; they are both necessary for efficient chemotaxis. Moreover, CheA-dependent phosphorylation of CheV is required for adaptation to attractants during B.subtilis chemotaxis.


ensembl_gene_id: BSU14040
symbol: ykuD
gene_biotype: protein_coding
description:
  Murein transglycosylase; Probable enzyme that may play an important role in cell wall biology; Belongs to the YkuD family.


ensembl_gene_id: BSU14050
symbol: ykuE
gene_biotype: protein_coding
description:
  Putative metallophosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallophosphoesterase superfamily.


ensembl_gene_id: BSU14060
symbol: fadH
gene_biotype: protein_coding
description:
  Putative 2,4-dienoyl-CoA reductase; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.


ensembl_gene_id: BSU14071
symbol: ykuG
gene_biotype: protein_coding
description:
  Putative cell wall protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: BSU14100
symbol: ykuJ
gene_biotype: protein_coding
description:
  Putative RNA-specific modification enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU14110
symbol: ykuK
gene_biotype: protein_coding
description:
  Putative RNAse; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU14120
symbol: abbA
gene_biotype: protein_coding
description:
  Regulator of AbrB repressor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU14130
symbol: ykuL
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11985717.


ensembl_gene_id: BSU14140
symbol: ccpC
gene_biotype: protein_coding
description:
  Transcriptional repressor of citB and citZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BSU14150
symbol: ykuN
gene_biotype: protein_coding
description:
  Short-chain flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: BSU14160
symbol: ykuO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229.


ensembl_gene_id: BSU14180
symbol: dapH
gene_biotype: protein_coding
description:
  Tetrahydrodipicolinate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.


ensembl_gene_id: BSU14190
symbol: dapL
gene_biotype: protein_coding
description:
  N-acetyl-diaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.


ensembl_gene_id: BSU14200
symbol: ykuS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0180 family.


ensembl_gene_id: BSU14210
symbol: ykuT
gene_biotype: protein_coding
description:
  Putative small-conductance mechanosensitive channel; May play a role in resistance to osmotic downshock. Belongs to the MscS (TC 1.A.23) family.


ensembl_gene_id: BSU14220
symbol: ykuU
gene_biotype: protein_coding
description:
  Putative 2-cys peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: BSU14230
symbol: ykuV
gene_biotype: protein_coding
description:
  Thiol-disulfide isomerase; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.


ensembl_gene_id: BSU14240
symbol: rok
gene_biotype: protein_coding
description:
  Repressor of comK; Repressor of comK, the master regulator of competence development. Overexpression seems to be lethal. Represses at least 20 genes that specify membrane- localized and secreted proteins, including some that encode products with antibiotic activity. Binds to many AT-rich sites in the chromosome, many of which are known or thought to derive from horizontal gene transfer; helps keep mobile element ICEBs1 quiescent in the genome. Binds to its own promoter and is thus probably autoregulatory.


ensembl_gene_id: BSU14250
symbol: yknT
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 15383836, 15743949.


ensembl_gene_id: BSU14260
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.


ensembl_gene_id: BSU14270
symbol: moeB
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis adenylyltransferase; Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein MoaD.


ensembl_gene_id: BSU14280
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdene to molybdopterin ligation enzyme; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP; Belongs to the MoeA family.


ensembl_gene_id: BSU14290
symbol: mobB
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein B; GTP-binding protein that is not required for the biosynthesis of Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor, and not necessary for the formation of active molybdoenzymes using this form of molybdenum cofactor. May act as an adapter protein to achieve the efficient biosynthesis and utilization of MGD. Displays a weak intrinsic GTPase activity (By similarity).


ensembl_gene_id: BSU14300
symbol: moaE
gene_biotype: protein_coding
description:
  Molybdopterin synthase (large subunit); Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family.


ensembl_gene_id: BSU14310
symbol: moaD
gene_biotype: protein_coding
description:
  Molybdopterin synthase (small subunit); Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin; Belongs to the MoaD family.


ensembl_gene_id: BSU14340
symbol: yknW
gene_biotype: protein_coding
description:
  Putative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex.


ensembl_gene_id: BSU14350
symbol: yknX
gene_biotype: protein_coding
description:
  Putative efflux permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).


ensembl_gene_id: BSU14360
symbol: yknY
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).


ensembl_gene_id: BSU14370
symbol: yknZ
gene_biotype: protein_coding
description:
  Putative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).


ensembl_gene_id: BSU14380
symbol: fruR
gene_biotype: protein_coding
description:
  Transcriptional regulator (DeoR family); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type r: regulator.


ensembl_gene_id: BSU14390
symbol: fruK
gene_biotype: protein_coding
description:
  Fructose-1-phosphate kinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU14400
symbol: fruA
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) fructose-specific enzyme IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport.


ensembl_gene_id: BSU14430
symbol: ykpA
gene_biotype: protein_coding
description:
  ABC efflux transporter (ATP-binding protein); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU14440
symbol: panE
gene_biotype: protein_coding
description:
  Ketopantoate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the ketopantoate reductase family.


ensembl_gene_id: BSU14470
symbol: mreBH
gene_biotype: protein_coding
description:
  Cell-shape determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreBH localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature (By similarity). Filaments rotate around the cell circumference in concert with the cell wall synthesis enzymes. The process is driven by the cell wall synthesis machinery and does not depend on MreBH polymerization. O [...]


ensembl_gene_id: BSU14480
symbol: abh
gene_biotype: protein_coding
description:
  Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; To B.subtilis AbrB and SpoVT.


ensembl_gene_id: BSU14510
symbol: ktrC
gene_biotype: protein_coding
description:
  Potassium uptake protein; Catalytic subunit of the KtrCD potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress.


ensembl_gene_id: BSU14520
symbol: adeC
gene_biotype: protein_coding
description:
  Adenine deaminase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.


ensembl_gene_id: BSU14530
symbol: rnjA
gene_biotype: protein_coding
description:
  Ribonuclease J1; An RNase that has endonuclease and 5'-3' exonuclease activity, playing a role in both rRNA and mRNA stability and degradation. Endonuclease activity can cleave within 4 nucleotides of the 5'-end of a triphosphorylated RNA. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides, on shorter substrates is distributive. Preferentially cleaves ssRNA, possibly in AU-rich regions. The 5'-exonuc [...]


ensembl_gene_id: BSU14540
symbol: rnpZA
gene_biotype: protein_coding
description:
  Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family.


ensembl_gene_id: BSU14560
symbol: defB
gene_biotype: protein_coding
description:
  Formylmethionine deformylase A; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: BSU14568
symbol: BSU14568
gene_biotype: protein_coding
description:
  Putative antitoxin; Evidence 5: No homology to any previously reported sequences; Product type pr: putative regulator.


ensembl_gene_id: BSU14570
symbol: ykyA
gene_biotype: protein_coding
description:
  Putative chromosome partitioning protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU14580
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (E1 alpha subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: BSU14590
symbol: pdhB
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (E1 beta subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: BSU14600
symbol: pdhC
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase (dihydrolipoamide acetyltransferase E2 subunit); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: BSU14610
symbol: pdhD
gene_biotype: protein_coding
description:
  Dihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: BSU14620
symbol: slp
gene_biotype: protein_coding
description:
  Small peptidoglycan-associated lipoprotein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.


ensembl_gene_id: BSU14629
symbol: rgpA
gene_biotype: protein_coding
description:
  Regulator of GapA synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU14640
symbol: yktA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19429628; Belongs to the UPF0223 family.


ensembl_gene_id: BSU14650
symbol: yktB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0637 family.


ensembl_gene_id: BSU14670
symbol: suhB
gene_biotype: protein_coding
description:
  Inositol monophosphatase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the inositol monophosphatase superfamily.


ensembl_gene_id: BSU14700
symbol: nprE
gene_biotype: protein_coding
description:
  Extracellular neutral metalloprotease; Extracellular zinc metalloprotease; Belongs to the peptidase M4 family.


ensembl_gene_id: BSU14710
symbol: ylaA
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307.


ensembl_gene_id: BSU14730
symbol: ylaC
gene_biotype: protein_coding
description:
  RNA polymerase ECF-type sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance.


ensembl_gene_id: BSU14740
symbol: ylaD
gene_biotype: protein_coding
description:
  anti-YlaC sigma factor; Anti-sigma factor for YlaC; Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily.


ensembl_gene_id: BSU14770
symbol: bipA
gene_biotype: protein_coding
description:
  GTPase; A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.


ensembl_gene_id: BSU14810
symbol: ylaK
gene_biotype: protein_coding
description:
  Putative phosphate starvation inducible protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; In the C-terminal section; belongs to the PhoH family.


ensembl_gene_id: BSU14860
symbol: pycA
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic function in B.subtilis as it is necessary for growth on glucose, but is not required for sporulation.


ensembl_gene_id: BSU14870
symbol: ctaA
gene_biotype: protein_coding
description:
  heme-A synthase; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group. Also involved in the sporulation.


ensembl_gene_id: BSU14880
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase 2; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.


ensembl_gene_id: BSU14890
symbol: ctaC
gene_biotype: protein_coding
description:
  Cytochrome caa3 oxidase (subunit II); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: BSU14900
symbol: ctaD
gene_biotype: protein_coding
description:
  Cytochrome caa3 oxidase (subunit I); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme a of subunit 1 to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer.


ensembl_gene_id: BSU14910
symbol: ctaE
gene_biotype: protein_coding
description:
  Cytochrome caa3 oxidase (subunit III); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the cytochrome c oxidase subunit 3 family.


ensembl_gene_id: BSU14920
symbol: ctaF
gene_biotype: protein_coding
description:
  Cytochrome caa3 oxidase (subunit IV); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the cytochrome c oxidase bacterial subunit 4 family.


ensembl_gene_id: BSU14930
symbol: ctaG
gene_biotype: protein_coding
description:
  Cytochrome aa(3) assembly factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU14990
symbol: ylbF
gene_biotype: protein_coding
description:
  Putative regulatory protein; Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation, stability or activity of ComS. May work together with YmcA to regulate community development.


ensembl_gene_id: BSU15010
symbol: rsmD
gene_biotype: protein_coding
description:
  Putative ribosomal RNA small subunit methyltransferase D; May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA.


ensembl_gene_id: BSU15020
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: BSU15040
symbol: ylbK
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NTE family.


ensembl_gene_id: BSU15050
symbol: ylbL
gene_biotype: protein_coding
description:
  Putative degradative enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU15060
symbol: ylbM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.


ensembl_gene_id: BSU15070
symbol: ylbN
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11700356.


ensembl_gene_id: BSU15080
symbol: rpmF
gene_biotype: protein_coding
description:
  Ribosomal protein L32; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.


ensembl_gene_id: BSU15090
symbol: gerR
gene_biotype: protein_coding
description:
  DNA-binding regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU15110
symbol: panE-2
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: BSU15120
symbol: bshC
gene_biotype: protein_coding
description:
  Malate glucosamine cysteine ligase; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.


ensembl_gene_id: BSU15130
symbol: mraZ
gene_biotype: protein_coding
description:
  Putative protein involved in cell division or replication; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process; Belongs to the MraZ family.


ensembl_gene_id: BSU15140
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-dependent methyltransferase active on membrane-located substrates; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: BSU15150
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell-division protein; Essential cell division protein that may play a structural role. Probably involved in the regulation of the timing of cell division. Also required for sporulation.


ensembl_gene_id: BSU15160
symbol: pbpB
gene_biotype: protein_coding
description:
  Penicillin-binding protein 2B; Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. PBP-2B is required for vegetative cell division and sporulation septation. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins, thereby interrupting normal cell wall synthesis; Belongs to the transpeptidase family.


ensembl_gene_id: BSU15170
symbol: spoVD
gene_biotype: protein_coding
description:
  Penicillin-binding protein; Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell.


ensembl_gene_id: BSU15180
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: BSU15190
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: BSU15200
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: BSU15210
symbol: spoVE
gene_biotype: protein_coding
description:
  Factor for spore cortex peptidoglycan synthesis (stage V sporulation); May play an essential role not only during sporulation, but also during vegetative growth; Belongs to the SEDS family. SpoVE subfamily.


ensembl_gene_id: BSU15220
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: BSU15240
symbol: divIB
gene_biotype: protein_coding
description:
  Cell-division initiation protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex. Plays an essential role in division at high temperatures, maybe by protecting FtsL from degradation or by promoting formation of the FtsL-DivIC complex. May modulate the transpeptidase activity of PBP-2B. Also required for efficient sporulation at all temperatures. Could be directly involved in the engulfment process or be required to form a sporulation septum competent for engulfment. Influences the Spo0J/Soj system of chromosome segregation. B [...]


ensembl_gene_id: BSU15250
symbol: ylxW
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; May be involved in cell division and sporulation. Belongs to the UPF0749 family.


ensembl_gene_id: BSU15280
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell-division protein essential fo Z-ring assembly; Cell division protein that is required for the assembly of the Z ring. May serve as a membrane anchor for the Z ring (By similarity). Binds and hydrolyzes ATP. Also involved in sporulation (Probable). Belongs to the FtsA/MreB family.


ensembl_gene_id: BSU15290
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell-division initiation protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: BSU15310
symbol: spoIIGA
gene_biotype: protein_coding
description:
  Protease processing pro-sigma-E; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.


ensembl_gene_id: BSU15320
symbol: sigE
gene_biotype: protein_coding
description:
  RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes.


ensembl_gene_id: BSU15330
symbol: sigG
gene_biotype: protein_coding
description:
  RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore.


ensembl_gene_id: BSU15340
symbol: ylmA
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: BSU15350
symbol: thiQ
gene_biotype: protein_coding
description:
  N-formyl-4-amino-5-aminomethyl-2- methylpyrimidinedeformylase; Catalyzes the deformylation of the formylaminopyrimidine N- formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP) to give the corresponding aminopyrimidine; Belongs to the peptidase M20A family.


ensembl_gene_id: BSU15360
symbol: ylmC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060.


ensembl_gene_id: BSU15380
symbol: ylmE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.


ensembl_gene_id: BSU15390
symbol: sepF
gene_biotype: protein_coding
description:
  Cell division machinery factor; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA; Belongs to the SepF family.


ensembl_gene_id: BSU15400
symbol: ylmG
gene_biotype: protein_coding
description:
  Factor involved in shape determination and osmotic tolerance; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.


ensembl_gene_id: BSU15410
symbol: ylmH
gene_biotype: protein_coding
description:
  Factor involved in shape determination, RNA-binding fold; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.


ensembl_gene_id: BSU15420
symbol: divIVA
gene_biotype: protein_coding
description:
  Cell-division initiation protein; May act as a pilot protein, directing MinCD to the polar septation sites or by inhibiting MinCD at the midcell site of division. Required for polar localization of the chromosome during sporulation.


ensembl_gene_id: BSU15430
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).


ensembl_gene_id: BSU15440
symbol: ylyA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987.


ensembl_gene_id: BSU15450
symbol: lspA
gene_biotype: protein_coding
description:
  Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.


ensembl_gene_id: BSU15470
symbol: pyrR
gene_biotype: protein_coding
description:
  Transcriptional attenuator and uracil phosphoribosyltransferase activity; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.


ensembl_gene_id: BSU15480
symbol: pyrP
gene_biotype: protein_coding
description:
  Uracil permease; Transport of uracil in the cell; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.


ensembl_gene_id: BSU15490
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU15510
symbol: pyrAA
gene_biotype: protein_coding
description:
  Pyrimidine-specific carbamoyl-phosphate synthetase (small subunit, glutaminase subunit); Evidence 2b: Function of strongly homologous gene; enzyme.


ensembl_gene_id: BSU15520
symbol: pyrAB
gene_biotype: protein_coding
description:
  Pyrimidine-specific carbamoyl-phosphate synthetase (large subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the CarB family.


ensembl_gene_id: BSU15530
symbol: pyrK
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (electron transfer subunit); Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD subunit to the ultimate electron acceptor NAD(+); Belongs to the PyrK family.


ensembl_gene_id: BSU15540
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (catalytic subunit); Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.


ensembl_gene_id: BSU15550
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: BSU15560
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: BSU15590
symbol: sat
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU15600
symbol: cysC
gene_biotype: protein_coding
description:
  Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate; Belongs to the APS kinase family.


ensembl_gene_id: BSU15610
symbol: sumT
gene_biotype: protein_coding
description:
  Uroporphyrinogen III and precorrin-1 C-methyltransferase; Catalyzes both methylations at C-2 and C-7 of uroporphyrinogen III leading to precorrin-1 and precorrin-2; their oxidative esterification gives respectively factor I octamethyl ester and sirohydrochlorin.


ensembl_gene_id: BSU15620
symbol: sirB
gene_biotype: protein_coding
description:
  Sirohydrochlorin ferrochelatase; Chelates iron to the siroheme precursor; Belongs to the CbiX family. SirB subfamily.


ensembl_gene_id: BSU15630
symbol: sirC
gene_biotype: protein_coding
description:
  Precorrin-2 dehydrogenase; Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin which is used as a precursor in both siroheme biosynthesis and in the anaerobic branch of adenosylcobalamin biosynthesis; Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: BSU15640
symbol: yloA
gene_biotype: protein_coding
description:
  Putative persistent RNA/DNA binding protein; Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. Selectively binds tRNA(Ala)(UGC), which is presumably the sole source of tRNA(Ala) used for Ala tailing directed by this protein. May add between 1 and at least 8 Ala residues; detection of the Ala tail requires either deletion of clpP or its inhibition. Binds to 50S ribosomal  [...]


ensembl_gene_id: BSU15650
symbol: yloB
gene_biotype: protein_coding
description:
  P-type calcium transport ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.


ensembl_gene_id: BSU15660
symbol: yloC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0701 family.


ensembl_gene_id: BSU15670
symbol: ylzA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Regulates the biosynthesis of the extracellular matrix and the biofilm formation. Activates the transcription of the matrix biosynthesis operons eps and tapA-sipW- tasA. Also activates expression of the opuA operon, involved in osmoprotection. Acts by binding specifically to the promoter region of the target genes. Acts in parallel to the pathway that governs SinR derepression. Required for endosporulation.


ensembl_gene_id: BSU15690
symbol: rpoZ
gene_biotype: protein_coding
description:
  Omega subunit of RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).


ensembl_gene_id: BSU15700
symbol: coaBC
gene_biotype: protein_coding
description:
  Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'- phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'- phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: BSU15710
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal replication factor Y (primosomal protein N'); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: BSU15720
symbol: defA
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).


ensembl_gene_id: BSU15730
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: BSU15750
symbol: rlmN
gene_biotype: protein_coding
description:
  23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: BSU15760
symbol: prpC
gene_biotype: protein_coding
description:
  Phosphorylated protein phosphatase; Protein phosphatase that dephosphorylates PrkC and EF-G (elongation factor G, fusA). prpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, PrpC's primary role being possibly to counter the action of PrkC. May be involved in sporulation and biofilm formation. Does not seem to be involved in stress response. Dephosphorylates phosphorylated CgsA, EF-Tu and YezB.


ensembl_gene_id: BSU15770
symbol: prkC
gene_biotype: protein_coding
description:
  Protein kinase; Protein kinase that is responsible for triggering spore germination in response to muropeptides, signaling bacteria to exit dormancy. PrkC is thus a germination receptor that binds peptidoglycan fragments containing m-Dpm (meso-diaminopimelate), which act as spore germinants. Autophosphorylates and phosphorylates EF-G (elongation factor G, fusA); the latter modification is likely necessary for germination in response to peptidoglycan. Another group did not detect phosphorylation of EF-G. PrkC is a substrate in vitro of the cotranscribed phosphatase PrpC, which suggests  [...]


ensembl_gene_id: BSU15780
symbol: cpgA
gene_biotype: protein_coding
description:
  GTPase involved in ribosome and sacculus morphogenesis; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase with a low level of activity and slow catalytic turnover, does not act on ATP. GTPase activity is stimulated by the presence of 30S or 70S ribosomes, phosphorylation increases stimulation. Depletion results in increased sensitivity to protein synthesis inhibitors that block the [...]


ensembl_gene_id: BSU15790
symbol: rpe
gene_biotype: protein_coding
description:
  Ribulose-5-phosphate 3-epimerase; Catalyzes the reversible epimerization of D-ribulose 5- phosphate to D-xylulose 5-phosphate; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: BSU15810
symbol: spoVM
gene_biotype: protein_coding
description:
  Factor required for normal spore cortex and coat synthesis (stage V sporulation); Coordinates cortex and coat assembly during sporulation. Associates with the spore coat protein SpoIVA and with the outer forespore membrane, thereby serving as a membrane anchor that tethers SpoIVA and the entire spore coat to the forespore surface. May also serve as a competitive inhibitor of FtsH activity during sporulation.


ensembl_gene_id: BSU15820
symbol: rpmB
gene_biotype: protein_coding
description:
  Ribosomal protein L28; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.


ensembl_gene_id: BSU15830
symbol: yloU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16014871, 17114254; Belongs to the asp23 family.


ensembl_gene_id: BSU15840
symbol: yloV
gene_biotype: protein_coding
description:
  Putative dihydroxyacetone/glyceraldehyde kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU15850
symbol: sdaAB
gene_biotype: protein_coding
description:
  L-serine dehydratase (beta chain); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: BSU15860
symbol: sdaAA
gene_biotype: protein_coding
description:
  L-serine dehydratase (alpha chain); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: BSU15870
symbol: recG
gene_biotype: protein_coding
description:
  Branch migrating ATP-dependent DNA helicase involved in DNA recombination and repair; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA) (By similarity); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: BSU15880
symbol: fapR
gene_biotype: protein_coding
description:
  Transcription factor controlling fatty acid and phospholipid metabolism; Transcription factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. Binds to the 5'-TTAGTANNNNNTANTAA-3' consensus sequence found in the promoter of fabHAF operon (containing fabHA and fabF genes), yhdO and fapR genes and prevents their expression. Its action is probably modulated by malonyl-CoA.


ensembl_gene_id: BSU15890
symbol: plsX
gene_biotype: protein_coding
description:
  phosphate:acyl-ACP acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: BSU15900
symbol: fabD
gene_biotype: protein_coding
description:
  Malonyl CoA:acyl carrier protein transacylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the FabD family.


ensembl_gene_id: BSU15910
symbol: fabG
gene_biotype: protein_coding
description:
  Beta-ketoacyl-acyl carrier protein reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU15920
symbol: acpA
gene_biotype: protein_coding
description:
  Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: BSU15930
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of ribosomal RNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes pre-scRNA (the precursor of the signal recognition particle RNA). Probably also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Probably processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: BSU15940
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome condensation and segregation SMC ATPase; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: BSU15950
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle (docking protein); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: BSU15970
symbol: ylxM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.


ensembl_gene_id: BSU15980
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle-like (SRP) GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individua [...]


ensembl_gene_id: BSU15990
symbol: rpsP
gene_biotype: protein_coding
description:
  Ribosomal protein S16 (BS17); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU16000
symbol: ylqC
gene_biotype: protein_coding
description:
  Putative RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the UPF0109 family.


ensembl_gene_id: BSU16020
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: BSU16030
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA(m1G37)methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: BSU16040
symbol: rplS
gene_biotype: protein_coding
description:
  Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; Belongs to the bacterial ribosomal protein bL19 family.


ensembl_gene_id: BSU16050
symbol: rbgA
gene_biotype: protein_coding
description:
  Ribosome biogenesis GTPase A; Essential protein that is required for a late step of 50S ribosomal subunit assembly. Has GTPase activity that is stimulated by interaction with the immature 50S ribosome subunit. Binds to the 23S rRNA. Required for the association of ribosomal proteins RplP and RpmA with the large subunit.


ensembl_gene_id: BSU16060
symbol: rnhB
gene_biotype: protein_coding
description:
  Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: BSU16080
symbol: ylqH
gene_biotype: protein_coding
description:
  Putative flagellar biosynthesis protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU16090
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase (beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: BSU16100
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase (alpha subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: BSU16110
symbol: dprA
gene_biotype: protein_coding
description:
  DNA processing Smf single strand binding protein; Protein that helps load RecA onto ssDNA during transformation. Binds cooperatively to circular ssDNA, is able to bridge different segments of DNA. Favors the loading of RecA onto SsbA- or SsbB-coated ssDNA and formation of RecA-DNA filaments. RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP.


ensembl_gene_id: BSU16120
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: BSU16130
symbol: trmFO
gene_biotype: protein_coding
description:
  tRNA:m(5)U-54 methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.


ensembl_gene_id: BSU16140
symbol: codV
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase for chromosome partitioning; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: BSU16150
symbol: clpQ
gene_biotype: protein_coding
description:
  Two-component ATP-dependent protease (N-terminal serine protease); Protease subunit of a proteasome-like degradation complex. Belongs to the peptidase T1B family. HslV subfamily.


ensembl_gene_id: BSU16160
symbol: clpY
gene_biotype: protein_coding
description:
  Two-component ATP-dependent protease (ATPase and chaperone); ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity; Belongs to the ClpX chaperone family. HslU subfamily.


ensembl_gene_id: BSU16170
symbol: codY
gene_biotype: protein_coding
description:
  Transcriptional regulator, GTP and BCAA-dependent; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase and sporulation. It is a GTP- binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor.


ensembl_gene_id: BSU16180
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar component of cell-proximal portion of basal-body rod; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: BSU16190
symbol: flgC
gene_biotype: protein_coding
description:
  Flagellar component of cell-proximal portion of basal-body rod; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: BSU16200
symbol: fliE
gene_biotype: protein_coding
description:
  Flagellar basal body protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure.


ensembl_gene_id: BSU16220
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing component; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation; Belongs to the FliG family.


ensembl_gene_id: BSU16240
symbol: fliI
gene_biotype: protein_coding
description:
  Flagellar-specific ATPase; Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.


ensembl_gene_id: BSU16260
symbol: ylxF
gene_biotype: protein_coding
description:
  Putative kinesin-like protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.


ensembl_gene_id: BSU16280
symbol: flgD
gene_biotype: protein_coding
description:
  Flagellar hook assembly protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type pf: putative factor; Belongs to the FlgD family.


ensembl_gene_id: BSU16290
symbol: flgE
gene_biotype: protein_coding
description:
  Flagellar hook protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: BSU16299
symbol: ylzI
gene_biotype: protein_coding
description:
  Putative flagellar protein; Required for swarming motility. Increases flagellar power, probably via the flagellar stator components MotA and MotB.


ensembl_gene_id: BSU16300
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar basal-body associated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: BSU16310
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing component; One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation; Belongs to the FliM family.


ensembl_gene_id: BSU16320
symbol: fliY
gene_biotype: protein_coding
description:
  Flagellar motor switching and energizing phosphatase; Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attractant to cope with increased levels of CheY-P; Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: BSU16330
symbol: cheY
gene_biotype: protein_coding
description:
  Regulator of chemotaxis and motility; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. Phosphorylated CheY interacts with the flagella switch components FliM and FliY, which causes counterclockwise rotation of the flagella, resulting in smooth swimming.


ensembl_gene_id: BSU16340
symbol: fliZ
gene_biotype: protein_coding
description:
  Flagellar regulatory protein; May be a structural component of the flagellum that anchors the rod to the membrane.


ensembl_gene_id: BSU16350
symbol: fliP
gene_biotype: protein_coding
description:
  Component of the flagellar export machinery; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: BSU16360
symbol: fliQ
gene_biotype: protein_coding
description:
  Component of the flagellar export machinery; Role in flagellar biosynthesis; Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: BSU16370
symbol: fliR
gene_biotype: protein_coding
description:
  Component of the flagellar export machinery; Role in flagellar biosynthesis; Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: BSU16380
symbol: flhB
gene_biotype: protein_coding
description:
  Component of the flagellar export machinery; May be involved in the export of flagellum proteins; Belongs to the type III secretion exporter family.


ensembl_gene_id: BSU16400
symbol: flhF
gene_biotype: protein_coding
description:
  GTPase involved in the export of flagella; Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.


ensembl_gene_id: BSU16410
symbol: ylxH
gene_biotype: protein_coding
description:
  Essential component of the flagellar assembly machinery; Involved in the placement and assembly of flagella (By similarity). Activates the SRP-GTPase activity of FlhF.


ensembl_gene_id: BSU16420
symbol: cheB
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis proteins (MCP)-glutamate methylesterase; Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR. B.subtilis has an effective methylation-independent adaptation system but must utilize the methylation system for adaptation to high concentrations of attractant; Belongs to the CheB family.


ensembl_gene_id: BSU16430
symbol: cheA
gene_biotype: protein_coding
description:
  Chemotactic two-component sensor histidine kinase; Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to CheB, CheY or CheV.


ensembl_gene_id: BSU16440
symbol: cheW
gene_biotype: protein_coding
description:
  Modulation of CheA activity in response to attractants (chemotaxis); Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheV and CheW are involved in the coupling of the methyl-accepting chemoreceptors to the central two- component kinase CheA; they are both necessary for efficient chemotaxis.


ensembl_gene_id: BSU16450
symbol: cheC
gene_biotype: protein_coding
description:
  CheY-P phosphatase CheC; Involved in restoring normal CheY-P levels following the addition of attractant by increasing the rate of CheY-P hydrolysis. Is only 6% as active as FliY, which indicates that CheC may function after addition of an attractant to cope with increased levels of CheY-P whereas FliY may function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P. In addition, it was shown to prevent methylation of the methyl-accepting chemotaxis proteins (MCPs). Inhibits CheD.


ensembl_gene_id: BSU16460
symbol: cheD
gene_biotype: protein_coding
description:
  Chemoreceptor glutamine deamidase CheD; Deamidates 'Gln-593' and 'Gln-594' of the chemoreceptor McpA. In addition, deamidates other chemoreceptors, including McpB and McpC. CheD-mediated MCP (methyl-accepting chemotaxis proteins) deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase. CheD is absolutely required for a behavioral response mediated by McpC but is not required for the response to asparagine mediated by McpB. CheD is necessary for the generation of wild-type prestimulus CheA autophosphorylation levels. Al [...]


ensembl_gene_id: BSU16470
symbol: sigD
gene_biotype: protein_coding
description:
  RNA polymerase sigma-28 factor (sigma-D); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This alternative sigma factor is required for the transcription of the flagellin and motility genes as well as for wild- type chemotaxis.


ensembl_gene_id: BSU16480
symbol: ylxL
gene_biotype: protein_coding
description:
  Coupling factor for flagellin transcription and translation; Required for swarming motility and for maximal sigma-D activity.


ensembl_gene_id: BSU16490
symbol: rpsB
gene_biotype: protein_coding
description:
  Ribosomal protein S2; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: BSU16500
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity); Belongs to the EF-Ts family.


ensembl_gene_id: BSU16510
symbol: pyrH
gene_biotype: protein_coding
description:
  Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP, with ATP or dATP as the most efficient phosphate donors. Is also able to phosphorylate 5-fluoro-UMP and 6-aza-UMP.


ensembl_gene_id: BSU16520
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: BSU16530
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: BSU16540
symbol: cdsA
gene_biotype: protein_coding
description:
  Phosphatidate cytidylyltransferase (CDP-diglyceride synthase); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU16550
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: BSU16560
symbol: rseP
gene_biotype: protein_coding
description:
  Regulator of sigma-W protease RasP; Is responsible for site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor. Can also cleave liberated signal peptides of PenP and Mpr, probably within in the cell membrane.


