# geneInfo

ensembl_gene_id: BSU16570
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: BSU16580
symbol: polC
gene_biotype: protein_coding
description:
  DNA polymerase III (alpha subunit); Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity; Belongs to the DNA polymerase type-C family. PolC subfamily.


ensembl_gene_id: BSU16590
symbol: rimP
gene_biotype: protein_coding
description:
  Ribosome maturation factor; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: BSU16600
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription translation coupling factor involved in Rho-dependent transcription termination; Participates in both transcription termination and antitermination.


ensembl_gene_id: BSU16610
symbol: ylxR
gene_biotype: protein_coding
description:
  Putative RNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU16620
symbol: rplGA
gene_biotype: protein_coding
description:
  Ribosomal protein L7Ae; RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs.


ensembl_gene_id: BSU16630
symbol: infB
gene_biotype: protein_coding
description:
  Initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: BSU16650
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: BSU16660
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: BSU16670
symbol: ribC
gene_biotype: protein_coding
description:
  Bifunctional riboflavin kinase FAD synthase; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.


ensembl_gene_id: BSU16680
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15 (BS18); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.


ensembl_gene_id: BSU16690
symbol: pnpA
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. Necessary for competence development in Bacillus subtilis. May be necessary for modification of the srfA transcript (stabilization or translation activation).


ensembl_gene_id: BSU16700
symbol: ylxY
gene_biotype: protein_coding
description:
  Putative sugar deacetylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the polysaccharide deacetylase family.


ensembl_gene_id: BSU16710
symbol: mlpA
gene_biotype: protein_coding
description:
  Specific processing protease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU16720
symbol: ymxH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the YlmC/YmxH family.


ensembl_gene_id: BSU16730
symbol: spoVFA
gene_biotype: protein_coding
description:
  Spore dipicolinate synthase subunit A; Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore.


ensembl_gene_id: BSU16740
symbol: spoVFB
gene_biotype: protein_coding
description:
  Spore dipicolinate synthase subunit B; Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore.


ensembl_gene_id: BSU16750
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: BSU16760
symbol: dapG
gene_biotype: protein_coding
description:
  Aspartokinase I (alpha and beta subunits); Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. Belongs to the aspartokinase family.


ensembl_gene_id: BSU16770
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: BSU16780
symbol: rnjB
gene_biotype: protein_coding
description:
  Ribonuclease J2; Endonucleolytically cleaves the 5'-leader sequence of certain mRNAs. Endonuclease digestion by the RNase J1/J2 complex occurs at a different site and in some cases more efficiently than J1 or J2 alone. The exonuclease activity of the J1/J2 complex is highly processive on substrates longer than 5 nucleotides, on shorter substrates is distributive. Plays a role in mRNA maturation and stability. Appears to have a limited effect on 16S rRNA maturation, despite its similarity to RNase J1. This subunit alone has very poor 5'-3' exonuclease activity. Belongs to the metallo-be [...]


ensembl_gene_id: BSU16790
symbol: tepA
gene_biotype: protein_coding
description:
  Protein export-enhancing factor; Required for efficient translocation of pre-proteins across the membrane; Belongs to the peptidase S14 family. TepA subfamily.


ensembl_gene_id: BSU16800
symbol: spoIIIE
gene_biotype: protein_coding
description:
  Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...]


ensembl_gene_id: BSU16845
symbol: ymfF
gene_biotype: protein_coding
description:
  Putative metalloprotease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase M16 family.


ensembl_gene_id: BSU16860
symbol: ymfH
gene_biotype: protein_coding
description:
  Putative processing protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU16920
symbol: pgsA
gene_biotype: protein_coding
description:
  CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: BSU16930
symbol: cinA
gene_biotype: protein_coding
description:
  Competence-damage inducible regulator; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the CinA family.


ensembl_gene_id: BSU16940
symbol: recA
gene_biotype: protein_coding
description:
  Multifunctional SOS repair factor; Multifunctional protein involved in homologous recombination, DNA repair and competence. Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange). RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP. It interacts with LexA causing its activation and leading to its autocatalytic clea [...]


ensembl_gene_id: BSU16950
symbol: pbpX
gene_biotype: protein_coding
description:
  Penicillin-binding endopeptidase X; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the beta-lactamase family.


ensembl_gene_id: BSU16960
symbol: rny
gene_biotype: protein_coding
description:
  Endoribonuclease Y; Endoribonuclease that initiates mRNA decay. Initiates the decay of all SAM-dependent riboswitches, such as yitJ riboswitch. Involved in processing of the gapA operon mRNA, it cleaves between cggR and gapA. Is also the decay-initiating endonuclease for rpsO mRNA. Belongs to the RNase Y family.


ensembl_gene_id: BSU16970
symbol: ymdB
gene_biotype: protein_coding
description:
  Putative hydrolase involved in biofilm formation; Plays a central, regulatory role in the late adaptive responses and affects the levels of many genes. May act via regulation of cAMP levels. Decreases the expression of motility genes and induces genes involved in biofilm formation, by controlling the expression of SlrR. Required for formation of intercellular nanotubes that bridge neighboring cells to allow molecular exchange. Plays a key role in directing the early stages of colony development. In vitro, has a metal-dependent phosphodiesterase activity against 2',3'-cAMP and 2',3'-cGM [...]


ensembl_gene_id: BSU16980
symbol: spoVS
gene_biotype: protein_coding
description:
  Stage V sporulation protein S; Induced early in sporulation under the control of sigma-H. Interferes with sporulation at an early stage. Seems to play a positive role in allowing cells to progress beyond stage V of sporulation.


ensembl_gene_id: BSU16990
symbol: tdh
gene_biotype: protein_coding
description:
  Threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: BSU17000
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate CoA ligase (glycine acetyl transferase); Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: BSU17010
symbol: miaB
gene_biotype: protein_coding
description:
  Enzyme for ms(2)i(6)A formation for tRNA modification; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: BSU17020
symbol: ymcA
gene_biotype: protein_coding
description:
  Master regulator for biofilm formation; May work together with YlbF to regulate community development.


ensembl_gene_id: BSU17030
symbol: cotE
gene_biotype: protein_coding
description:
  Morphogenic spore protein; Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA, cotB, cotC, cotH and other genes encoding spore outer coat proteins.


ensembl_gene_id: BSU17040
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair recognition factor; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). Overexpression of mutSL partially suppresses the high spontaneous mutation frequency of a ytkD/mutM/mutY triple disruption which lacks the system required to prevent damage by oxidized guanine (8-oxo-dGTP). This suggests that MutSL also functions to repair mismatches due to oxidative stress in both growing and stationary phase cells.


ensembl_gene_id: BSU17050
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair factor; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). Overexpression of mutSL partially suppresses the high spontaneous mutation frequency of a ytkD/mutM/mutY triple disruption which lacks the system required to prevent damage by oxidized guanine (8-oxo [...]


ensembl_gene_id: BSU17090
symbol: pksB
gene_biotype: protein_coding
description:
  Putative hydrolase; Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism; Belongs to the metallo-beta-lactamase superfamily.


ensembl_gene_id: BSU17100
symbol: pksC
gene_biotype: protein_coding
description:
  malonyl-CoA-acyltransferase involved in polyketide synthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the transfer of the malonyl-CoA group to the acyl-carrier-protein AcpK (Mal-AcpK); Belongs to the FabD family.


ensembl_gene_id: BSU17110
symbol: pksD
gene_biotype: protein_coding
description:
  Enzyme involved in polyketide synthesis; Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.


ensembl_gene_id: BSU17120
symbol: pksE
gene_biotype: protein_coding
description:
  Enzyme involved in polyketide synthesis; Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductase activity; In the N-terminal section; belongs to the FabD family.


ensembl_gene_id: BSU17130
symbol: acpK
gene_biotype: protein_coding
description:
  Acyl-carrier protein; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.


ensembl_gene_id: BSU17140
symbol: pksF
gene_biotype: protein_coding
description:
  Decarboxylase converting malonyl-S-AcpK to acetyl-S-AcpK for polyketide synthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It decarboxylates selectively the malonyl group attached on the acyl-carrier-protein AcpK (Mal-AcpK); Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: BSU17150
symbol: pksG
gene_biotype: protein_coding
description:
  acetyl-S-AcpK beta-ketothioester polyketide intermediate transferase; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. It catalyzes the aldol condensation between the acetyl group attached to the acyl-carrier-protein AcpK (Ac-AcpK) and a beta- ketothioester polyketide intermediate linked to one of the consecutive thiolation domains of PksL; Belongs to the thiolase-like superfamily. HMG-CoA synthase family.


ensembl_gene_id: BSU17160
symbol: pksH
gene_biotype: protein_coding
description:
  Dehydratase for polyketide biosynthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. Probably catalyzes the dehydration of the (S)-3-hydroxy-3- methylglutaryl group attached to PksL.


ensembl_gene_id: BSU17170
symbol: pksI
gene_biotype: protein_coding
description:
  Decarboxylase involved in polyketide synthesis; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism. May have a role in the decarboxylation of the (S)-3- methylglutaryl group attached to PksL.


ensembl_gene_id: BSU17180
symbol: pksJ
gene_biotype: protein_coding
description:
  Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.


ensembl_gene_id: BSU17200
symbol: pksM
gene_biotype: protein_coding
description:
  Polyketide synthase; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.


ensembl_gene_id: BSU17230
symbol: pksS
gene_biotype: protein_coding
description:
  Cytochrome P450 of bacillaene metabolism; Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene.


ensembl_gene_id: BSU17260
symbol: aprX
gene_biotype: protein_coding
description:
  Alkaline serine protease; Displays serine protease activity. Seems to have a broad substrate specificity.


ensembl_gene_id: BSU17280
symbol: ymaD
gene_biotype: protein_coding
description:
  Putative peroxiredoxin-related protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the OsmC/Ohr family.


ensembl_gene_id: BSU17290
symbol: ebrB
gene_biotype: protein_coding
description:
  Small multidrug efflux transporter; Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O. The efflux is probably coupled to an influx of protons (By similarity).


ensembl_gene_id: BSU17300
symbol: ebrA
gene_biotype: protein_coding
description:
  Small multidrug resistance efflux transporter; Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O. The efflux is probably coupled to an influx of protons (By similarity).


ensembl_gene_id: BSU17310
symbol: ymaG
gene_biotype: protein_coding
description:
  Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU17330
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: BSU17340
symbol: hfq
gene_biotype: protein_coding
description:
  Hfq RNA chaperone; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: BSU17370
symbol: nrdI
gene_biotype: protein_coding
description:
  Co-factor of ribonucleotide diphosphate reductase; Probably involved in ribonucleotide reductase function.


ensembl_gene_id: BSU17380
symbol: nrdE
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase (major subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).


ensembl_gene_id: BSU17390
symbol: nrdF
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase (minor subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).


ensembl_gene_id: BSU17400
symbol: ymaB
gene_biotype: protein_coding
description:
  Putative enzyme involved in deoxyribonucleotide synthesis; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU17410
symbol: cwlC
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella - in particular of its basal body - and sporulation. CwlC is able to hydrolyze type A cell walls such as B.subtilis. Its main function is to lyze the mother cell wall peptidoglycan, playing a role during sporulation. Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.


ensembl_gene_id: BSU17420
symbol: spoVK
gene_biotype: protein_coding
description:
  Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU17430
symbol: hflX
gene_biotype: protein_coding
description:
  Ribosome associating GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.


ensembl_gene_id: BSU17440
symbol: ynbB
gene_biotype: protein_coding
description:
  Putative C-S lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU17450
symbol: glnR
gene_biotype: protein_coding
description:
  Transcriptional regulator (nitrogen metabolism); Transcription repressor that represses many genes including ureABC and tnrA, during nitrogen excess. On the contrary of the MerR members, which require longer DNA sites for high-affinity binding, GlnR requires a DNA sequence of 17 nucleotides as minimal binding site.


ensembl_gene_id: BSU17460
symbol: glnA
gene_biotype: protein_coding
description:
  Glutamine synthetase; Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism. It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. Feedback-inhibited GlnA interacts with and regulates the activity of the transcriptional regulator TnrA. During nitrogen limitation, TnrA is in its DNA- binding active state and turns on the transcription of genes required for nitrogen assimilation. Under condi [...]


ensembl_gene_id: BSU17490
symbol: ynzG
gene_biotype: protein_coding
description:
  Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; Belongs to the UPF0457 family.


ensembl_gene_id: BSU17560
symbol: ynaI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To L.lactis TrpF C-terminal region.


ensembl_gene_id: BSU17570
symbol: xynP
gene_biotype: protein_coding
description:
  Putative H+-xyloside symporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU17580
symbol: xynB
gene_biotype: protein_coding
description:
  Xylan beta-1,4-xylosidase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: BSU17600
symbol: xylA
gene_biotype: protein_coding
description:
  Xylose isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the xylose isomerase family.


ensembl_gene_id: BSU17610
symbol: xylB
gene_biotype: protein_coding
description:
  Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: BSU17620
symbol: yncB
gene_biotype: protein_coding
description:
  DNA nuclease, lipoprotein; Shows DNase activity on double strand DNA. Belongs to the thermonuclease family.


ensembl_gene_id: BSU17640
symbol: alrB
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: BSU17650
symbol: yncE
gene_biotype: protein_coding
description:
  Putative prophage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU17660
symbol: yncF
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.


ensembl_gene_id: BSU17680
symbol: thyA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: BSU17700
symbol: cotC
gene_biotype: protein_coding
description:
  Spore coat protein (outer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.


ensembl_gene_id: BSU17710
symbol: tatAC
gene_biotype: protein_coding
description:
  Component of the twin-arginine pre-protein translocation pathway; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: BSU17730
symbol: yndB
gene_biotype: protein_coding
description:
  Putative stress-related ATPase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the AHA1 family.


ensembl_gene_id: BSU17760
symbol: yndE
gene_biotype: protein_coding
description:
  Putative spore germination integral inner membrane protein; Involved in the germinative response to L-alanine. Could be an amino acid transporter (By similarity); Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.


ensembl_gene_id: BSU17770
symbol: yndF
gene_biotype: protein_coding
description:
  Putative spore germination lipoprotein; May be involved in spore germination. Belongs to the GerABKC lipoprotein family.


ensembl_gene_id: BSU17810
symbol: yndK
gene_biotype: protein_coding
description:
  Putative phage/plasmid replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU17820
symbol: yndL
gene_biotype: protein_coding
description:
  Putative phage-related replication protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; Belongs to the UPF0714 family.


ensembl_gene_id: BSU17840
symbol: fosB
gene_biotype: protein_coding
description:
  Metallothiol transferase; Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.


ensembl_gene_id: BSU17850
symbol: lexA
gene_biotype: protein_coding
description:
  Transcriptional repressor of the SOS regulon; Represses dinA, dinB, dinC, recA genes and itself by binding to the 14 bp palindromic sequence 5'-CGAACNNNNGTTCG-3'; some genes have a tandem consensus sequence and their binding is cooperative. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair; autocleavage is maximal at pH 11 in the absence of RecA and ssDNA.


ensembl_gene_id: BSU17860
symbol: yneA
gene_biotype: protein_coding
description:
  Cell division inhibitor; Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and/or DivIC to the division machinery (By similarity).


ensembl_gene_id: BSU17870
symbol: yneB
gene_biotype: protein_coding
description:
  Putative cell division protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process.


ensembl_gene_id: BSU17880
symbol: ynzC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12581363, 16267290, 18431750, 19306341; Belongs to the UPF0291 family.


ensembl_gene_id: BSU17890
symbol: tkt
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: BSU17900
symbol: pcfA
gene_biotype: protein_coding
description:
  Factor controlling DNA replication; Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation.


ensembl_gene_id: BSU17930
symbol: ccdA
gene_biotype: protein_coding
description:
  Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat.


ensembl_gene_id: BSU17940
symbol: yneI
gene_biotype: protein_coding
description:
  Putative response regulator (CheY homolog); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU17970
symbol: cotM
gene_biotype: protein_coding
description:
  Spore coat protein (outer); Involved in spore outer coat assembly. May be part of a cross-linked insoluble skeleton that surrounds the spore, serves as a matrix for the assembly of additional outer coat material, and confers structural stability to the final structure.


ensembl_gene_id: BSU17980
symbol: sspP
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspP family.


ensembl_gene_id: BSU17990
symbol: sspO
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspO family.


ensembl_gene_id: BSU18000
symbol: citB
gene_biotype: protein_coding
description:
  Aconitate hydratase (aconitase); Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles. Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the rehydration of 2- methyl-cis-aconitate to produce 2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein which plays a role in the regulation of citrate concentration and in the sporulation. To prevent the accumulation of excessive levels of citrate, it binds near the 5' end of the citZ mRNA, decreasing its stability and thereby limiting the conce [...]


ensembl_gene_id: BSU18010
symbol: yneN
gene_biotype: protein_coding
description:
  Putative membrane-bound proteins with a thioredoxin-like domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thioredoxin family.


ensembl_gene_id: BSU18020
symbol: sspN
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspN family.


ensembl_gene_id: BSU18030
symbol: tlp
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein (thioredoxin-like protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the Tlp family.


ensembl_gene_id: BSU18060
symbol: yneR
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the HesB/IscA family.


ensembl_gene_id: BSU18070
symbol: plsY
gene_biotype: protein_coding
description:
  Acylphosphate:glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP; Belongs to the PlsY family.


ensembl_gene_id: BSU18080
symbol: yneT
gene_biotype: protein_coding
description:
  Putative CoA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU18090
symbol: parE
gene_biotype: protein_coding
description:
  Subunit B of DNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily.


ensembl_gene_id: BSU18100
symbol: parC
gene_biotype: protein_coding
description:
  Subunit A of DNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 2 subfamily.


ensembl_gene_id: BSU18120
symbol: alsT
gene_biotype: protein_coding
description:
  Amino acid carrier protein; Evidence 2b: Function of strongly homologous gene; Product type t: transporter; Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.


ensembl_gene_id: BSU18130
symbol: eglS
gene_biotype: protein_coding
description:
  Endo-1,4-beta-glucanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU18150
symbol: xynC
gene_biotype: protein_coding
description:
  Endo-xylanase; Catalyzes the depolymerization of methylglucuronoxylan (MeGAXn) from different sources. It cleaves the beta-1,4-xylosidic bond penultimate to that linking carbon one of the xylose residue substituted with alpha-1,2-linked 4-O-methyl-D-glucuronate (MeGA). Belongs to the glycosyl hydrolase 30 family.


ensembl_gene_id: BSU18160
symbol: xynD
gene_biotype: protein_coding
description:
  Arabinoxylan arabinofuranohydrolase; Cleaves arabinose units from O-2- or O-3-monosubstituted xylose residues, thereby assisting in arabinoxylan (AX) and short-chain arabinoxylo-oligosaccharide (AXOS) degradation. Is more active on wheat bran AXOS than on wheat water-extractable AX and rye water-extractable AX. Does not display endoxylanase, xylosidase or arabinanase activity.


ensembl_gene_id: BSU18170
symbol: yngA
gene_biotype: protein_coding
description:
  Putative conserved membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU18180
symbol: yngB
gene_biotype: protein_coding
description:
  Putative UTP-glucose-1-phosphate uridylyltransferase; Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) (By similarity).


ensembl_gene_id: BSU18200
symbol: nrnB
gene_biotype: protein_coding
description:
  Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines.


ensembl_gene_id: BSU18210
symbol: yngE
gene_biotype: protein_coding
description:
  Putative methylcrotonoyl-CoA carboxylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the AccD/PCCB family.


ensembl_gene_id: BSU18220
symbol: yngF
gene_biotype: protein_coding
description:
  Putative Methylglutaconyl-CoA hydratase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: BSU18230
symbol: yngG
gene_biotype: protein_coding
description:
  Putative hydroxymethylglutaryl-CoA lyase; Involved in the catabolism of branched amino acids such as leucine; Belongs to the HMG-CoA lyase family.


ensembl_gene_id: BSU18239
symbol: yngHB
gene_biotype: protein_coding
description:
  acyl-CoA carboxylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type c: carrier.


ensembl_gene_id: BSU18240
symbol: yngHA
gene_biotype: protein_coding
description:
  Biotin carboxylase/methylcrotonoyl-CoA carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: BSU18250
symbol: yngI
gene_biotype: protein_coding
description:
  Putative acetoacetyl-CoA synthetase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e: enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU18260
symbol: yngJ
gene_biotype: protein_coding
description:
  acyl-CoA dehydrogenase, short-chain specific; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the acyl-CoA dehydrogenase family.


ensembl_gene_id: BSU18280
symbol: yngK
gene_biotype: protein_coding
description:
  Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.


ensembl_gene_id: BSU18300
symbol: ppsE
gene_biotype: protein_coding
description:
  Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acid Ile as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The activation sites for this amino acid consist of individual domains; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU18310
symbol: ppsD
gene_biotype: protein_coding
description:
  Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Pro, Gln and Tyr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Tyr residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU18320
symbol: ppsC
gene_biotype: protein_coding
description:
  Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Ala/Val residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU18330
symbol: ppsB
gene_biotype: protein_coding
description:
  Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Tyr and Thr as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The Thr residue is further converted to the D-allo-isomer form. The activation sites for these amino acids consist of individual domains. Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU18340
symbol: ppsA
gene_biotype: protein_coding
description:
  Plipastatin synthetase; This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Orn as part of the biosynthesis of the lipopeptide antibiotic lipastatin. The Orn residue is further epimerized to the D-isomer form. The activation sites for these amino acids consist of individual domains; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU18360
symbol: galM
gene_biotype: protein_coding
description:
  Aldose 1-epimerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the aldose epimerase family.


ensembl_gene_id: BSU18380
symbol: iseA
gene_biotype: protein_coding
description:
  Inhibitor of cell-separation enzymes; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU18390
symbol: yoeC
gene_biotype: protein_coding
description:
  Putative bacteriophage integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the 'phage' integrase family.


ensembl_gene_id: BSU18400
symbol: yoeD
gene_biotype: protein_coding
description:
  Putative excisionase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU18410
symbol: ggt
gene_biotype: protein_coding
description:
  Membrane bound gamma-glutamyltranspeptidase; Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases; Belongs to the gamma-glutamyltransferase family.


ensembl_gene_id: BSU18420
symbol: ftsR
gene_biotype: protein_coding
description:
  Transcriptional regulator (LysR family); Regulates expression of the cell division protein ftsW, and is essential for cell viability during stationary phase.


ensembl_gene_id: BSU18430
symbol: yogA
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU18440
symbol: gltB
gene_biotype: protein_coding
description:
  Glutamate synthase (small subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU18450
symbol: gltA
gene_biotype: protein_coding
description:
  Glutamate synthase (large subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glutamate synthase family.


ensembl_gene_id: BSU18460
symbol: gltC
gene_biotype: protein_coding
description:
  Transcriptional regulator (LysR family); Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression.


ensembl_gene_id: BSU18480
symbol: proH
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: BSU18490
symbol: rtp
gene_biotype: protein_coding
description:
  Replication terminator protein; Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat.


ensembl_gene_id: BSU18500
symbol: yoxD
gene_biotype: protein_coding
description:
  Putative oxido-reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU18530
symbol: yoaA
gene_biotype: protein_coding
description:
  Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransferase family.


ensembl_gene_id: BSU18540
symbol: yoaB
gene_biotype: protein_coding
description:
  Negatively charged metabolite transporter; Evidence 2b: Function of strongly homologous gene; Product type t: transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. CsbX subfamily.


ensembl_gene_id: BSU18550
symbol: yoaC
gene_biotype: protein_coding
description:
  Hydroxylated metabolite kinase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.


ensembl_gene_id: BSU18560
symbol: yoaD
gene_biotype: protein_coding
description:
  Putative 2-hydroxyacid dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU18590
symbol: yoaG
gene_biotype: protein_coding
description:
  Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU18610
symbol: yoaH
gene_biotype: protein_coding
description:
  Putative methyl-accepting chemotaxis protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU18620
symbol: yoaI
gene_biotype: protein_coding
description:
  Putative 4-hydroxyphenylacetate-3-hydroxylase; Catalyzes the hydroxylation of 4-hydroxyphenylacetic acid (4HPA), leading to the production of 3,4-dihydroxyphenylacetic acid (DHPA).


ensembl_gene_id: BSU18630
symbol: exlX
gene_biotype: protein_coding
description:
  Extracellular endoglucanase precursor (expansin); May promote colonization of plant roots. May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. Has very low expansin activity (in vitro). No enzymatic activity has been found. Binds to peptidoglycan and to plant cell walls.


ensembl_gene_id: BSU18650
symbol: pelB
gene_biotype: protein_coding
description:
  Pectin lyase; Catalyzes the depolymerization of pectins of methyl esterification degree from 13 to 75%, with an endo mode of action. Cannot degrade polygalacturonate (By similarity).


ensembl_gene_id: BSU18660
symbol: yoaM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross- link with DNA (By similarity). May act as a protease: mediates autocatalytic processing of its N-terminal methionine in order to expose the catalytic cysteine (By similarity).


ensembl_gene_id: BSU18690
symbol: yoaP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the acetyltransferase family.


ensembl_gene_id: BSU18720
symbol: yoaR
gene_biotype: protein_coding
description:
  Putative factor for cell wall maintenance or synthesis; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU18760
symbol: yoaU
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (LysR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BSU18770
symbol: cyeA
gene_biotype: protein_coding
description:
  Cysteine and O-acetyl serine efflux permease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: BSU18780
symbol: yoaW
gene_biotype: protein_coding
description:
  Biofilm forming exported protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.


ensembl_gene_id: BSU18790
symbol: yoaZ
gene_biotype: protein_coding
description:
  Putative factor of the oxidative stress response; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the peptidase C56 family.


ensembl_gene_id: BSU18800
symbol: penP
gene_biotype: protein_coding
description:
  Beta-lactamase precursor; This protein is a beta-lactamase with a substrate specificity for penicillins.


ensembl_gene_id: BSU18830
symbol: pps
gene_biotype: protein_coding
description:
  Putative PEP-dependent enzyme; Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate.


ensembl_gene_id: BSU18840
symbol: xynA
gene_biotype: protein_coding
description:
  Endo-1,4-beta-xylanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 11 (cellulase G) family.


ensembl_gene_id: BSU18850
symbol: yobD
gene_biotype: protein_coding
description:
  Transcriptional regulator (phage-related, Xre family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU18880
symbol: yobE
gene_biotype: protein_coding
description:
  Putative phage protein; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross- link with DNA (By similarity). May act as a protease: mediates autocatalytic processing of its N-terminal methionine in order to expose the catalytic cysteine (By similarity).


ensembl_gene_id: BSU18908
symbol: yozY
gene_biotype: protein_coding
description:
  Putative transcriptional regulator from bacteriophage; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU18910
symbol: rapK
gene_biotype: protein_coding
description:
  Putative phage holin (fragment); Evidence 7: Gene remnant; extrachromosomal origin; Belongs to the RAP family.


ensembl_gene_id: BSU18920
symbol: phrK
gene_biotype: protein_coding
description:
  Secreted regulator of the activity of phosphatase RapK; Inhibitor of the activity of phosphatase RapK.


ensembl_gene_id: BSU18930
symbol: yobH
gene_biotype: protein_coding
description:
  Putative DNA repair protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the DNA polymerase type-Y family.


ensembl_gene_id: BSU18940
symbol: yozK
gene_biotype: protein_coding
description:
  Putative DNA repair protein fragment; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.


ensembl_gene_id: BSU18950
symbol: yozL
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951.


ensembl_gene_id: BSU18960
symbol: yozM
gene_biotype: protein_coding
description:
  Putative bacteriophage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU18970
symbol: yobI
gene_biotype: protein_coding
description:
  Putative NTPase with transmembrane helices; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU18980
symbol: yobJ
gene_biotype: protein_coding
description:
  Small regulatory RNA; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type n: RNA.


ensembl_gene_id: BSU18990
symbol: rttM
gene_biotype: protein_coding
description:
  Antitoxin inhibiting Rnase RttL; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the RNase activity of cognate toxin YobL, as well as its ability to inhibit growth upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain.


ensembl_gene_id: BSU19000
symbol: rttL
gene_biotype: protein_coding
description:
  Phage toxin ribonuclease; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 449-600) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK, but not by antitoxins specific to other toxins with the LXG domain.


ensembl_gene_id: BSU19020
symbol: yobN
gene_biotype: protein_coding
description:
  Putative amine oxidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the flavin monoamine oxidase family. FIG1 subfamily.


ensembl_gene_id: BSU19030
symbol: yobO
gene_biotype: protein_coding
description:
  Putative phage-related pre-neck appendage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU19040
symbol: csaA
gene_biotype: protein_coding
description:
  Molecular chaperone; Can suppress growth and secretion defects in E.coli secA and secB mutants. Probably a molecular chaperone for exported proteins or may act by stabilizing the SecA protein.


ensembl_gene_id: BSU19090
symbol: yobU
gene_biotype: protein_coding
description:
  Putative effector of transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU19110
symbol: yobW
gene_biotype: protein_coding
description:
  Mother cell-specific membrane sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU19120
symbol: czrA
gene_biotype: protein_coding
description:
  Transcriptional regulator (multiple metal-sensing ArsR-SmtB transcriptional repressors family); Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA.


ensembl_gene_id: BSU19130
symbol: yocA
gene_biotype: protein_coding
description:
  Putative transposon-related lytic enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU19170
symbol: yocD
gene_biotype: protein_coding
description:
  Putative carboxypeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase S66 family.


ensembl_gene_id: BSU19180
symbol: des
gene_biotype: protein_coding
description:
  Fatty acid desaturase; Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids.


ensembl_gene_id: BSU19190
symbol: desK
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [DesR]; Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase. Acts as a sensor of the membrane fluidity. Probably activates DesR by phosphorylation.


ensembl_gene_id: BSU19200
symbol: desR
gene_biotype: protein_coding
description:
  Two-component response regulator [DesK]; Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase.


ensembl_gene_id: BSU19210
symbol: yocH
gene_biotype: protein_coding
description:
  Putative exported cell wall-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU19220
symbol: rtbI
gene_biotype: protein_coding
description:
  Ribonuclease toxin of toxin-antitoxin systems RttI-RttJ; Probable DNA helicase. Required for DNA repair and intramolecular recombination; probably has overlapping function with RecS (AC P50729). It probably acts to help generate ss-DNA from ds-DNA breaks; Belongs to the helicase family. RecQ subfamily.


ensembl_gene_id: BSU19230
symbol: rtbJ
gene_biotype: protein_coding
description:
  Antitoxin of ribonuclease RttI; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity. Confers resistance to catechol, 2- methylhydroquinone (2-MHQ), and diamide. Probably could also reduce benzoquinones produce by the auto-oxidation of catechol and 2- methylhydroquinone.


ensembl_gene_id: BSU19259
symbol: yoyB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19383706, 20709900.


ensembl_gene_id: BSU19260
symbol: yocM
gene_biotype: protein_coding
description:
  Putative spore coat protein; Part of the cellular protein quality control system with a specific role in salt stress response. May facilitate protein homeostasis, together with chemical chaperones that accumulate during the salt stress response. Increased levels of YocM protects against both heat and salt stress. In vitro, displays an unusual aggregase chaperone activity.


ensembl_gene_id: BSU19310
symbol: dhaS
gene_biotype: protein_coding
description:
  Putative aldehyde dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: BSU19320
symbol: sqhC
gene_biotype: protein_coding
description:
  Squalene-hopene cyclase; Catalyzes the cyclization of tetraprenyl beta-curcumene into sporulenol; Belongs to the terpene cyclase/mutase family.


ensembl_gene_id: BSU19330
symbol: sodF
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.


ensembl_gene_id: BSU19350
symbol: yocS
gene_biotype: protein_coding
description:
  Putative sodium-dependent transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU19360
symbol: odhB
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase complex (dihydrolipoamide transsuccinylase, E2 subunit); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: BSU19370
symbol: odhA
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase (E1 subunit); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: BSU19380
symbol: yojO
gene_biotype: protein_coding
description:
  Putative activator of nitric oxide reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU19390
symbol: yojN
gene_biotype: protein_coding
description:
  Putative nitric-oxide reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the CbbQ/NirQ/NorQ/GpvN family.


ensembl_gene_id: BSU19400
symbol: sodC
gene_biotype: protein_coding
description:
  Superoxide dismutase (exported lipoprotein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.


ensembl_gene_id: BSU19410
symbol: cwlS
gene_biotype: protein_coding
description:
  Peptidoglycan hydrolase (cell wall-binding d,l-endopeptidase); Probably functions as a cell separation enzyme in addition to LytE and LytF.


ensembl_gene_id: BSU19430
symbol: yojJ
gene_biotype: protein_coding
description:
  Putative enzyme with DAC domain; One of 3 paralogous diadenylate cyclases (DAC) in this bacteria, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP) (Probable). Upon expression in E.coli leads to c-di- AMP synthesis. Overexpression of the hyperactive mutant (L44F) in the absence of c-di-AMP phosphodiesterase GdpP leads to growth defects in log phase (long curly cell filaments) that disappear upon sporulation; spore formation is normal, showing sporulation is insensitive to the excess c-di-AMP. In B.subtilis c-di-AMP is a second messenger that mediates growth,  [...]


ensembl_gene_id: BSU19440
symbol: norM
gene_biotype: protein_coding
description:
  MatE Na+-driven efflux family protein; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.


ensembl_gene_id: BSU19460
symbol: bshBB
gene_biotype: protein_coding
description:
  Malate N-acetylglucosamine deacetylase (second enzyme); Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family.


ensembl_gene_id: BSU19490
symbol: gerT
gene_biotype: protein_coding
description:
  Component of the spore coat; Involved in spore germination; probably required at the earliest stage of germination.


ensembl_gene_id: BSU19520
symbol: yojA
gene_biotype: protein_coding
description:
  Putative H+/anion permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU19530
symbol: yodA
gene_biotype: protein_coding
description:
  Putative tautomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the 4-oxalocrotonate tautomerase family.


ensembl_gene_id: BSU19540
symbol: arxR
gene_biotype: protein_coding
description:
  Transcriptional repressor; Negatively regulates yodC and azoR1 which may contribute to the degradation of aromatic compounds. Probably positively regulates the catechol-specific transcription of mhqNOP, mhqED, and mhqA.


ensembl_gene_id: BSU19560
symbol: yodD
gene_biotype: protein_coding
description:
  Putative hydrolase; Putative hydrolase that may contribute to the degradation of aromatic compounds.


ensembl_gene_id: BSU19570
symbol: yodE
gene_biotype: protein_coding
description:
  Putative lyase/dioxygenase; Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds.


ensembl_gene_id: BSU19580
symbol: yodF
gene_biotype: protein_coding
description:
  Putative Na+/metabolite permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: BSU19590
symbol: ctpA
gene_biotype: protein_coding
description:
  Carboxy-terminal processing protease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU19600
symbol: yodH
gene_biotype: protein_coding
description:
  Putative S-adenosylmethionine-dependent methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the methyltransferase superfamily.


ensembl_gene_id: BSU19620
symbol: yodJ
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase lipoprotein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU19630
symbol: deoD
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; Cleavage of adenosine and its derivatives; Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: BSU19650
symbol: yodM
gene_biotype: protein_coding
description:
  Putative phospholipid phosphatase; Catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol. Also has undecaprenyl pyrophosphate phosphatase activity, required for the biosynthesis of the lipid carrier undecaprenyl phosphate.


ensembl_gene_id: BSU19680
symbol: yozE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0346 family.


ensembl_gene_id: BSU19690
symbol: kamA
gene_biotype: protein_coding
description:
  Lysine 2,3-aminomutase; Catalyzes the interconversion of L-alpha-lysine and L-beta- lysine; Belongs to the radical SAM superfamily. KamA family.


ensembl_gene_id: BSU19700
symbol: kamB
gene_biotype: protein_coding
description:
  Epsilon-amino-beta-lysine acetyl transferase; In vitro, is able to catalyze the acetylation of beta-lysine to N6-acetyl-beta-lysine, an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated.


ensembl_gene_id: BSU19710
symbol: yodQ
gene_biotype: protein_coding
description:
  Putative deacylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU19720
symbol: yodR
gene_biotype: protein_coding
description:
  Putative acyloate-acetoacetate CoA-transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU19730
symbol: yodS
gene_biotype: protein_coding
description:
  Putative aminoacyloate CoA-transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU19740
symbol: yodT
gene_biotype: protein_coding
description:
  Putative aminovalerate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU19749
symbol: yoyG
gene_biotype: protein_coding
description:
  Putative sporulation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU19750
symbol: cgeE
gene_biotype: protein_coding
description:
  Protein involved in maturation of the outermost layer of the spore; May be involved in maturation of the outermost layer of the spore.


ensembl_gene_id: BSU19800
symbol: phy
gene_biotype: protein_coding
description:
  Phytase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU19820
symbol: yotN
gene_biotype: protein_coding
description:
  Putative capsular polysaccharide biosynthesis enzyme fragment; Evidence 7: Gene remnant; putative enzyme.


ensembl_gene_id: BSU19830
symbol: yotM
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; extrachromosomal origin.


ensembl_gene_id: BSU19940
symbol: yotB
gene_biotype: protein_coding
description:
  Putative metallo-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU20020
symbol: yosS
gene_biotype: protein_coding
description:
  SPbeta phage deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: BSU20030
symbol: yosR
gene_biotype: protein_coding
description:
  SPbeta phage putative thiol disulfide oxidoreductase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; Belongs to the thioredoxin family.


ensembl_gene_id: BSU20040
symbol: yosP
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase 2, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: BSU20050
symbol: yosQ
gene_biotype: protein_coding
description:
  SPbeta phage endodeoxyribonuclease (homing endonuclease, responsible for intron mobility); A possible homing endonuclease, it is entirely encoded within the YosP intron.


ensembl_gene_id: BSU20060
symbol: nrdEB
gene_biotype: protein_coding
description:
  SPbeta phage ribonucleoside reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase large chain family.


ensembl_gene_id: BSU20070
symbol: nrdIB
gene_biotype: protein_coding
description:
  SPbeta phage subunit of nucleoside diphosphate reductase; Probably involved in ribonucleotide reductase function.


ensembl_gene_id: BSU20130
symbol: yosG
gene_biotype: protein_coding
description:
  Putative cell wall hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU20250
symbol: mtbP
gene_biotype: protein_coding
description:
  DNA (cytosine-5-)-methyltransferase; This enzyme methylates the first cytosine within the sequences GGCC and GCNGC; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: BSU20270
symbol: yorS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Dephosphorylates nucleoside monophosphates such as the 5' and 2'(3')-phosphates of deoxyribonucleotides in vitro. Also catalyzes the dephosphorylation of coenzyme A (CoA), pyridoxal-5'-phosphate (PLP), riboflavine-5-phosphate (FMN) and nicotinamide adenine dinucleotide phosphate (NADP) in vitro; Belongs to the 5'(3')-deoxyribonucleotidase family.


ensembl_gene_id: BSU20280
symbol: yorR
gene_biotype: protein_coding
description:
  Putative nucleotide kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU20360
symbol: yorJ
gene_biotype: protein_coding
description:
  Putative DNA replication initiation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU20370
symbol: yorI
gene_biotype: protein_coding
description:
  Putative replicative DNA helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU20450
symbol: yorA
gene_biotype: protein_coding
description:
  Putative capsid component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.


ensembl_gene_id: BSU20460
symbol: yoqZ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0714 family.


ensembl_gene_id: BSU20480
symbol: yoqX
gene_biotype: protein_coding
description:
  Putative SPbeta phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU20500
symbol: ligB
gene_biotype: protein_coding
description:
  Bacteriophage SPbeta DNA ligase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; Belongs to the ATP-dependent DNA ligase family.


ensembl_gene_id: BSU20580
symbol: yoqM
gene_biotype: protein_coding
description:
  Putative membrane bound protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU20590
symbol: yoqL
gene_biotype: protein_coding
description:
  Putative endonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HNH nuclease family.


ensembl_gene_id: BSU20670
symbol: yoqD
gene_biotype: protein_coding
description:
  Putative DNA-binding protein anti-repressor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU20680
symbol: yoqC
gene_biotype: protein_coding
description:
  Putative nucleotide-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU20790
symbol: yopR
gene_biotype: protein_coding
description:
  Putative integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU20810
symbol: yopP
gene_biotype: protein_coding
description:
  Putative phage integrase; Probable recombinase that does not seem to have a role in chromosome dimer resolution per se but rather may have some facilitative role during chromosome partitioning in general. Belongs to the 'phage' integrase family.


ensembl_gene_id: BSU20870
symbol: yopJ
gene_biotype: protein_coding
description:
  Putative nucleotide binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU20930
symbol: yopD
gene_biotype: protein_coding
description:
  Putative conserved hypothetical membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU20940
symbol: yopC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; May be the toxic component of a type II toxin-antitoxin (TA) system. Neutralized by its cognate antitoxin YopB. In the C-terminal section; belongs to the MbcT/ParT/Res family.


ensembl_gene_id: BSU20950
symbol: yopB
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; May be the antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the activity of cognate toxin YopC.


ensembl_gene_id: BSU21010
symbol: yonS
gene_biotype: protein_coding
description:
  Putative glycosyl hydrolase lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU21020
symbol: yonR
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (Xre family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU21040
symbol: yonO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; A single subunit DNA-dependent RNA polymerase (RNAP) that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates (rNTPs) as substrates. The enzyme is more highly processive than the multisubunit RNAP from E.coli but is considerably more error-prone. It has no detectable proof-reading function but can perform pyrophosphorolysis. Transcribes the late genes of the SPbeta prophage starting from yonK (approximately 35 genes are encoded in the prophage downstream from yonK).


ensembl_gene_id: BSU21050
symbol: yonN
gene_biotype: protein_coding
description:
  Putative HU-related DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family.


ensembl_gene_id: BSU21090
symbol: yonH
gene_biotype: protein_coding
description:
  Putative capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.


ensembl_gene_id: BSU21110
symbol: yonF
gene_biotype: protein_coding
description:
  Putative prophage terminase, ATP subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU21240
symbol: yomS
gene_biotype: protein_coding
description:
  Putative phage-related lytic exoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU21300
symbol: yomM
gene_biotype: protein_coding
description:
  Putative integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the 'phage' integrase family.


ensembl_gene_id: BSU21329
symbol: youB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10931276.


ensembl_gene_id: BSU21340
symbol: yomJ
gene_biotype: protein_coding
description:
  Putative phage immunity protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU21350
symbol: cwlP
gene_biotype: protein_coding
description:
  Lytic transglycosylase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; Belongs to the transglycosylase Slt family.


ensembl_gene_id: BSU21370
symbol: yomG
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU21390
symbol: yomE
gene_biotype: protein_coding
description:
  Putative glycosyl hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU21410
symbol: blyA
gene_biotype: protein_coding
description:
  Bacteriophage SPbeta N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Involved in prophage SP-beta-mediated cell lysis.


ensembl_gene_id: BSU21430
symbol: bhlB
gene_biotype: protein_coding
description:
  Holin-like bacteriophage SPbeta protein; May be involved in the secretion of the autolysin BlyA; Belongs to the SPP1 holin family.


ensembl_gene_id: BSU21440
symbol: bdbB
gene_biotype: protein_coding
description:
  Bacteriophage SPbeta thiol-disulfide oxidoreductase; Important but not absolutely essential for the production of the lantibiotic sublancin 168, it may also be required for the stability of other secreted proteins. Not required for competence for DNA uptake; Belongs to the DsbB family. BdbC subfamily.


ensembl_gene_id: BSU21450
symbol: sunS
gene_biotype: protein_coding
description:
  Sublancin glycosyltransferase; Transfers a hexose moiety onto 'Cys-41' of bacteriocin sublancin-168 (SunA). Accepts UDP-glucose (UDP-Glc), UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-galactose (UDP-Gal), UDP-xylose (UDP-Xyl) and GDP-mannose as substrate.


ensembl_gene_id: BSU21460
symbol: bdbA
gene_biotype: protein_coding
description:
  Bacteriophage SPbeta thiol-disulfide oxidoreductase; Unknown; dispensable for production of the lantibiotic sublancin 168 and for competence for DNA uptake; Belongs to the thioredoxin family.


ensembl_gene_id: BSU21470
symbol: sunT
gene_biotype: protein_coding
description:
  Sublancin 168 lantibiotic transporter; SunT (TC 3.A.1.112.4) is required for production of the lantibiotic sublancin-168, probably by both processing the signal peptide and exporting the resulting mature lantibiotic.


ensembl_gene_id: BSU21480
symbol: sunA
gene_biotype: protein_coding
description:
  Sublancin 168 lantibiotic antimicrobial precursor peptide in SPBeta prophage; Bacteriocin active against Gram-positive bacteria. Inhibits B.cereus spore outgrowth, after the germination stage, approximately 1000-fold better than it inhibits exponential growth of the same cells. Inhibits B.subtilis strain ATCC 6633.


ensembl_gene_id: BSU21490
symbol: sunI
gene_biotype: protein_coding
description:
  Protein of immunity to sublancin; Is essential and sufficient to confer resistance to the bacteriocin sublancin 168.


ensembl_gene_id: BSU21520
symbol: yolC
gene_biotype: protein_coding
description:
  SP beta phage protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU21540
symbol: yolA
gene_biotype: protein_coding
description:
  Putative exported protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU21546
symbol: bsrG
gene_biotype: protein_coding
description:
  Phage toxin; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.


ensembl_gene_id: BSU21570
symbol: yokJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the ability to inhibit growth of cognate toxin YokI upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain.


ensembl_gene_id: BSU21580
symbol: yokI
gene_biotype: protein_coding
description:
  Putative DNA wielding protein; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 449-571) inhibits growth upon expression in E.coli which is neutralized by cognate antitoxin YokJ, but not by antitoxins specific to other toxins with the LXG domain.


ensembl_gene_id: BSU21600
symbol: yokG
gene_biotype: protein_coding
description:
  Putative transposase fragment; Evidence 7: Gene remnant; putative enzyme; Belongs to the cry6A endotoxin family.


ensembl_gene_id: BSU21610
symbol: yokF
gene_biotype: protein_coding
description:
  SPbeta phage DNA nuclease, lipoprotein; Catalyzes the hydrolysis of supercoiled double and single strand DNA and RNA. Involved in chromosomal DNA degradation and cell death caused by thermal stress.


ensembl_gene_id: BSU21630
symbol: yokD
gene_biotype: protein_coding
description:
  Aminoglycoside N3'-acetyltransferase; May contribute to antibiotic resistance; Belongs to the antibiotic N-acetyltransferase family.


ensembl_gene_id: BSU21640
symbol: yokC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10376821.


ensembl_gene_id: BSU21650
symbol: yokB
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821.


ensembl_gene_id: BSU21660
symbol: yokA
gene_biotype: protein_coding
description:
  Putative DNA recombinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; In the N-terminal section; belongs to the site-specific recombinase resolvase family.


ensembl_gene_id: BSU21690
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. May deal with oxidative damage to alpha/beta-type SASP in spores.


ensembl_gene_id: BSU21710
symbol: dinF
gene_biotype: protein_coding
description:
  Damage inducible, Na+ driven multidrug efflux pump; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: BSU21740
symbol: ypmR
gene_biotype: protein_coding
description:
  Putative exported lipase/acylhydrolase (lipoprotein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU21750
symbol: scuA
gene_biotype: protein_coding
description:
  Assembly factor BSco of the Cu(A) site of cytochrome c oxidase; Necessary for insertion of copper into the active site of cytochrome c oxidase. May play a role in copper homeostasis or redox signaling; Belongs to the SCO1/2 family.


ensembl_gene_id: BSU21760
symbol: ypmP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15060025.


ensembl_gene_id: BSU21770
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity).


ensembl_gene_id: BSU21790
symbol: yplQ
gene_biotype: protein_coding
description:
  Putative membrane hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU21810
symbol: dfrA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).


ensembl_gene_id: BSU21820
symbol: thyB
gene_biotype: protein_coding
description:
  Thymidylate synthase B; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: BSU21830
symbol: ypjQ
gene_biotype: protein_coding
description:
  Putative phosphatidylglycerophosphatase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; To B.subtilis YutG.


ensembl_gene_id: BSU21860
symbol: bshR
gene_biotype: protein_coding
description:
  Protein disulfide isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the UPF0403 family.


ensembl_gene_id: BSU21870
symbol: ilvD
gene_biotype: protein_coding
description:
  Dihydroxy-acid dehydratase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the IlvD/Edd family.


ensembl_gene_id: BSU21880
symbol: ypgR
gene_biotype: protein_coding
description:
  Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU21900
symbol: bsaA
gene_biotype: protein_coding
description:
  Putative bacillithiol peroxidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glutathione peroxidase family.


ensembl_gene_id: BSU21910
symbol: metA
gene_biotype: protein_coding
description:
  Putative homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: BSU21920
symbol: ugtP
gene_biotype: protein_coding
description:
  UDP-glucose diacylglyceroltransferase; Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta- monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O- (beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D- glucopyranosyl)-1,2-diac [...]


ensembl_gene_id: BSU21930
symbol: cspD
gene_biotype: protein_coding
description:
  Cold-shock protein, molecular chaperone, RNA-helicase co-factor; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU21940
symbol: degR
gene_biotype: protein_coding
description:
  Activation of degradative enzymes (aprE, nprE, sacB) production or activity; Stabilizes the phosphorylated form of DegU, leading to enhanced production of levansucrase, alkaline protease, and neutral protease.


ensembl_gene_id: BSU21970
symbol: ypeP
gene_biotype: protein_coding
description:
  Ribonuclease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU21980
symbol: ypdP
gene_biotype: protein_coding
description:
  Putative integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: BSU21990
symbol: ypdQ
gene_biotype: protein_coding
description:
  Putative RNA binding protein; Not known; does not have RNase H activity; Belongs to the RNase H family. EbsB subfamily.


ensembl_gene_id: BSU22000
symbol: sspL
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU22030
symbol: dynA
gene_biotype: protein_coding
description:
  Dynamin-like GTPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU22040
symbol: bpsB
gene_biotype: protein_coding
description:
  Alkylpyrone methyltransferase BpsB; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: BSU22050
symbol: bpsA
gene_biotype: protein_coding
description:
  Promiscuous alkylpyrone synthase BpsA; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU22060
symbol: pbuX
gene_biotype: protein_coding
description:
  Xanthine permease; Transport of xanthine in the cell; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily.


ensembl_gene_id: BSU22070
symbol: xpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so that it can be reused for RNA or DNA synthesis; Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.


ensembl_gene_id: BSU22080
symbol: ypwA
gene_biotype: protein_coding
description:
  Metal-dependent carboxypeptidase; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues. Has lower activity with substrates ending with His or Trp; Belongs to the peptidase M32 family.


ensembl_gene_id: BSU22090
symbol: kdgT
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate permease; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity).


ensembl_gene_id: BSU22100
symbol: kdgA
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate-6-phosphate aldolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU22110
symbol: kdgK
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate kinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: BSU22120
symbol: kdgR
gene_biotype: protein_coding
description:
  Kdg operon transcriptional regulator (LacI family); Transcriptional repressor of the kdgRKAT and kduID operons for pectin utilization.


ensembl_gene_id: BSU22130
symbol: kduI
gene_biotype: protein_coding
description:
  4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.


ensembl_gene_id: BSU22140
symbol: kduD
gene_biotype: protein_coding
description:
  2-keto-3-deoxygluconate oxidoreductase; Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3-deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU22150
symbol: ypvA
gene_biotype: protein_coding
description:
  Putative ATP-dependent helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU22170
symbol: ypsC
gene_biotype: protein_coding
description:
  Putative methylase with RNA interaction domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the methyltransferase superfamily.


ensembl_gene_id: BSU22180
symbol: gpsB
gene_biotype: protein_coding
description:
  Cell division protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation; Belongs to the GpsB family.


ensembl_gene_id: BSU22190
symbol: ypsA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0398 family.


ensembl_gene_id: BSU22200
symbol: cotD
gene_biotype: protein_coding
description:
  Spore coat protein (inner); Evidence 1a: Function experimentally demonstrated in the studied strain; cell process.


ensembl_gene_id: BSU22210
symbol: yprB
gene_biotype: protein_coding
description:
  Putative nucleic acid binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU22220
symbol: yprA
gene_biotype: protein_coding
description:
  Putative ATP-dependent helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the helicase family.


ensembl_gene_id: BSU22230
symbol: ypqE
gene_biotype: protein_coding
description:
  Putative phosphotransferase system enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.


ensembl_gene_id: BSU22240
symbol: ypqA
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: BSU22260
symbol: yppF
gene_biotype: protein_coding
description:
  Putative site-specific integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU22280
symbol: yppD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15687200.


ensembl_gene_id: BSU22310
symbol: recU
gene_biotype: protein_coding
description:
  Holliday junction resolvase; Has at least 2 separable functions; Holliday junction resolution with generation of monomeric chromosomes, and modulation of RecA activity. Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation. Partially inhibits the hydrolysis of dATP or rATP by RecA. Holliday junction resolution is stimulated by RuvB.


ensembl_gene_id: BSU22320
symbol: ponA
gene_biotype: protein_coding
description:
  Peptidoglycan glycosyltransferase (penicillin-binding proteins 1A and 1B); Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: BSU22340
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate; Belongs to the Nth/MutY family.


ensembl_gene_id: BSU22350
symbol: dnaD
gene_biotype: protein_coding
description:
  DNA-remodelling primosomal protein; Probable component of primosome involved in the initiation of DNA replication.


ensembl_gene_id: BSU22360
symbol: asnS
gene_biotype: protein_coding
description:
  asparaginyl-tRNA synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU22370
symbol: aspB
gene_biotype: protein_coding
description:
  Putative aspartate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU22410
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: BSU22420
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: BSU22430
symbol: panB
gene_biotype: protein_coding
description:
  Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: BSU22440
symbol: birA
gene_biotype: protein_coding
description:
  Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.


ensembl_gene_id: BSU22450
symbol: cca
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity.


ensembl_gene_id: BSU22460
symbol: bshA
gene_biotype: protein_coding
description:
  Malate glycosyltransferase for bacillithiol synthesis; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the first step of the pathway, the formation of N-acetylglucosaminylmalate (GlcNAc-Mal) from UDP-N-acetylglucosamine (UDP-GlcNAc) and L-malate. Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.


ensembl_gene_id: BSU22470
symbol: bshBA
gene_biotype: protein_coding
description:
  Malate N-acetylglucosamine N-acetyl hydrolase; Involved in bacillithiol (BSH) biosynthesis. Catalyzes the second step of the pathway, the deacetylation of N- acetylglucosaminylmalate (GlcNAc-Mal) to glucosamine malate (GlcN-Mal). Belongs to the PIGL family.


ensembl_gene_id: BSU22490
symbol: dapB
gene_biotype: protein_coding
description:
  (4S)-4-hydroxy-2,3,4, 5-tetrahydro-(2S)-dipicolinic acid (HTPA) dehydratase reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.


ensembl_gene_id: BSU22500
symbol: ypjD
gene_biotype: protein_coding
description:
  Nucleotide phosphohydrolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU22520
symbol: ypjB
gene_biotype: protein_coding
description:
  Spore formation membrane associated protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.


ensembl_gene_id: BSU22540
symbol: qcrC
gene_biotype: protein_coding
description:
  Menaquinol:cytochrome c oxidoreductase (cytochrome cc subunit); Component of the menaquinol-cytochrome c reductase complex.


ensembl_gene_id: BSU22550
symbol: qcrB
gene_biotype: protein_coding
description:
  Menaquinol:cytochrome c oxidoreductase (cytochrome b subunit); Component of the menaquinol-cytochrome c reductase complex.


ensembl_gene_id: BSU22560
symbol: qcrA
gene_biotype: protein_coding
description:
  Menaquinol:cytochrome c oxidoreductase (iron-sulfur subunit); Component of the menaquinol-cytochrome c reductase complex. The Rieske protein is a high potential 2Fe-2S protein.


ensembl_gene_id: BSU22580
symbol: ypiB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16847875; Belongs to the UPF0302 family.


ensembl_gene_id: BSU22600
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvoylshikimate-3-phosphate synthase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: BSU22610
symbol: tyrA
gene_biotype: protein_coding
description:
  Prephenate dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the prephenate/arogenate dehydrogenase family.


ensembl_gene_id: BSU22620
symbol: hisC
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: BSU22630
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase (alpha subunit); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Belongs to the TrpA family.


ensembl_gene_id: BSU22640
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase (beta subunit); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: BSU22650
symbol: trpF
gene_biotype: protein_coding
description:
  Phosphoribosyl anthranilate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the TrpF family.


ensembl_gene_id: BSU22670
symbol: trpD
gene_biotype: protein_coding
description:
  Indole-3-glycerol phosphate synthase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: BSU22680
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of am [...]


ensembl_gene_id: BSU22690
symbol: aroH
gene_biotype: protein_coding
description:
  Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.


ensembl_gene_id: BSU22700
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: BSU22710
symbol: aroF
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: BSU22720
symbol: cheR
gene_biotype: protein_coding
description:
  Methyl-accepting chemotaxis proteins (MCPs) methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents.


ensembl_gene_id: BSU22730
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: BSU22740
symbol: hepT
gene_biotype: protein_coding
description:
  Heptaprenyl diphosphate synthase component II; Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7). Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: BSU22750
symbol: menH
gene_biotype: protein_coding
description:
  Menaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: BSU22760
symbol: hepS
gene_biotype: protein_coding
description:
  Heptaprenyl diphosphate synthase component I; Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7).


ensembl_gene_id: BSU22770
symbol: mtrB
gene_biotype: protein_coding
description:
  Tryptophan operon RNA-binding attenuation protein (TRAP); Required for transcription attenuation control in the trp operon. This trans-acting factor binds to trinucleotide repeats (GAG or UAG) located in the trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan. Belongs to the MtrB family.


ensembl_gene_id: BSU22780
symbol: folEA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase I; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the GTP cyclohydrolase I family.


ensembl_gene_id: BSU22790
symbol: hbs
gene_biotype: protein_coding
description:
  Non-specific DNA-binding protein HBsu; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Binds evenly across chromosome, does not display a preference for AT content.


ensembl_gene_id: BSU22800
symbol: spoIVA
gene_biotype: protein_coding
description:
  Morphogenetic stage IV sporulation protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat outer layers. Its ATP hydrolysis is required for proper assembly of the spore coat. Forms a basement layer around the outside surface of the forespore and self-assembles irreversibly into higher order structures by binding and hydrolyzing ATP thus creating a durable and stable platform upon which thereafter morphogenesis of the coat can take place. Required for proper localization of spore coat protein CotE and sporulation-specific proteins including SpoVM.


ensembl_gene_id: BSU22830
symbol: gpsA
gene_biotype: protein_coding
description:
  NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Involved in the biosynthesis of the sn-glycerol 3-phosphate required for phospholipid synthesis.


ensembl_gene_id: BSU22840
symbol: engA
gene_biotype: protein_coding
description:
  GTPase essential for ribosome 50S subunit assembly; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: BSU22870
symbol: fni
gene_biotype: protein_coding
description:
  Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: BSU22880
symbol: rpfA
gene_biotype: protein_coding
description:
  RNA degradation presenting factor (ribosomal protein S1 homolog); Plays a role in sporulation; Belongs to the bacterial ribosomal protein bS1 family.


ensembl_gene_id: BSU22910
symbol: ypfA
gene_biotype: protein_coding
description:
  Putative cyclic diGMP binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU22920
symbol: ypeB
gene_biotype: protein_coding
description:
  Spore membrane component; Required for spore cortex hydrolysis during germination. Appears to be required for either expression, localization, activation or function of SleB.


ensembl_gene_id: BSU22930
symbol: sleB
gene_biotype: protein_coding
description:
  Spore cortex-lytic enzyme; Could be a lytic transglycosylase. Required for spore cortex hydrolysis during germination. Interacts strongly but noncovalently with spore components.


ensembl_gene_id: BSU22940
symbol: prsW
gene_biotype: protein_coding
description:
  Protease required for RsiW anti-sigma(W) degradation; Involved in the degradation of anti-sigma-W factor RsiW. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor. Seems to be responsible for sensing antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress. Therefore it is a protease governing regulated intramembrane proteolysis and r [...]


ensembl_gene_id: BSU22950
symbol: ypdA
gene_biotype: protein_coding
description:
  Putative FAD-dependent disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU22960
symbol: gudB
gene_biotype: protein_coding
description:
  Cryptic glutamate dehydrogenase; GudB seems to be intrinsically inactive, however spontaneous mutations removing a 9-bp direct repeat within the wild-type gudB sequence activated the GudB protein and allowed more-efficient utilization of amino acids of the glutamate family. This insertion presumably causes severe destabilization of the fold of the protein, leading to an inactive enzyme that is very quickly degraded. The cryptic GudB serves as a buffer that may compensate for mutations in the rocG gene and that can also be decryptified for the utilization of glutamate as a single carbon [...]


ensembl_gene_id: BSU22970
symbol: mecB
gene_biotype: protein_coding
description:
  Regulator of competence and sporulation; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved in Spx degradation by ClpC (By similarity). Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation.


ensembl_gene_id: BSU22980
symbol: ypbG
gene_biotype: protein_coding
description:
  Putative phosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU23000
symbol: ypbE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855244.


ensembl_gene_id: BSU23010
symbol: ypbD
gene_biotype: protein_coding
description:
  Putative membrane protease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU23020
symbol: recQ
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase; Probable DNA helicase. Required in synaptic and/or post- synaptic stages of recombination. Probably has overlapping function with RecQ (AC O34748). It probably acts to help generate ss-DNA from ds-DNA breaks.


ensembl_gene_id: BSU23040
symbol: fer
gene_biotype: protein_coding
description:
  Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. This ferredoxin may act as a phosphodonor to cytochrome P450 BioI.


ensembl_gene_id: BSU23050
symbol: fmnP
gene_biotype: protein_coding
description:
  FMN permease; Mediates uptake of riboflavin and roseoflavin, a toxic riboflavin analog; may also transport FMN. Probably a riboflavin- binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity). Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.


ensembl_gene_id: BSU23070
symbol: serA
gene_biotype: protein_coding
description:
  3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.


ensembl_gene_id: BSU23080
symbol: aroC
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.


ensembl_gene_id: BSU23090
symbol: rsiX
gene_biotype: protein_coding
description:
  Negative regulator of sigma(X) activity; The anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigX, inhibits SigX activity and stabilizes it.


ensembl_gene_id: BSU23100
symbol: sigX
gene_biotype: protein_coding
description:
  RNA polymerase ECF(extracytoplasmic function)-type sigma factor sigma(X); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. May be involved in the regulation of iron metabolism; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: BSU23110
symbol: resE
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Member of the two-component regulatory system ResD/ResE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates ResD.


ensembl_gene_id: BSU23120
symbol: resD
gene_biotype: protein_coding
description:
  Two-component response regulator; Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration.


ensembl_gene_id: BSU23150
symbol: resA
gene_biotype: protein_coding
description:
  Extracytoplasmic thioredoxin involved in cytochrome c maturation (lipoprotein); Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached. Does not play a role in sporulation. Belongs to the thioredoxin family. ResA subfamily.


ensembl_gene_id: BSU23160
symbol: rluB
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-2633 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: BSU23170
symbol: spmB
gene_biotype: protein_coding
description:
  Spore maturation protein; Involved in spore core dehydration; might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure; Belongs to the SpmB family.


ensembl_gene_id: BSU23180
symbol: spmA
gene_biotype: protein_coding
description:
  Spore maturation protein; Involved in spore core dehydration; might be involved in the transport of something into or out of the forespore or could be required for some modification of the cortex peptidoglycan structure.


ensembl_gene_id: BSU23190
symbol: dacB
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5*); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. Required specifically for the synthesis of the spore form of peptidoglycan (cortex).


ensembl_gene_id: BSU23200
symbol: ypuI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12065423.


ensembl_gene_id: BSU23210
symbol: spcB
gene_biotype: protein_coding
description:
  Chromosome condensation and segregation factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves; Belongs to the ScpB family.


ensembl_gene_id: BSU23220
symbol: scpA
gene_biotype: protein_coding
description:
  Chromosome condensation and partitioning factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves; Belongs to the ScpA family.


ensembl_gene_id: BSU23250
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. Is able to use the non-natural R enantiomer of 3,4- dihydroxy-2-butanone 4-phosphate as a substrate, but with less efficiency than the natural S enantiomer. Cannot use unphosphorylated 3,4-dihydroxy-2-butanone, 3,4-dihydroxy-2-butanone 3-phosphate or diacetyl as substrates.


ensembl_gene_id: BSU23260
symbol: ribAB
gene_biotype: protein_coding
description:
  Fused GTP cyclohydrolase II and 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.


ensembl_gene_id: BSU23270
symbol: ribE
gene_biotype: protein_coding
description:
  Riboflavin synthase (alpha subunit); Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil.


ensembl_gene_id: BSU23280
symbol: ribD
gene_biotype: protein_coding
description:
  Fused diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: BSU23310
symbol: sipS
gene_biotype: protein_coding
description:
  Type I signal peptidase; Not essential for cell viability, but required for efficient secretion of many proteins.


ensembl_gene_id: BSU23350
symbol: ypzD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the GerPA/GerPF family.


ensembl_gene_id: BSU23360
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: BSU23380
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: BSU23390
symbol: spoVAF
gene_biotype: protein_coding
description:
  Stage V sporulation protein AF; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU23401
symbol: spoVAEA
gene_biotype: protein_coding
description:
  Stage V sporulation germinant protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU23402
symbol: spoVAEB
gene_biotype: protein_coding
description:
  Spore germinant protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU23410
symbol: spoVAD
gene_biotype: protein_coding
description:
  Stage V sporulation protein AD; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU23420
symbol: spoVAC
gene_biotype: protein_coding
description:
  Stage V sporulation protein AC; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU23430
symbol: spoVAB
gene_biotype: protein_coding
description:
  Stage V sporulation protein AB; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU23440
symbol: spoVAA
gene_biotype: protein_coding
description:
  Stage V sporulation protein AA; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU23450
symbol: sigF
gene_biotype: protein_coding
description:
  RNA polymerase sporulation-specific sigma factor (sigma-F); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. Interaction with SpoIIAB inhibits sigma-F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore. Responsible for expression of csfB (the anti-sigma-G factor Gin).


ensembl_gene_id: BSU23460
symbol: spoIIAB
gene_biotype: protein_coding
description:
  Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.


ensembl_gene_id: BSU23470
symbol: spoIIAA
gene_biotype: protein_coding
description:
  Anti-anti-sigma factor (antagonist of SpoIIAB); In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition; Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: BSU23480
symbol: dacF
gene_biotype: protein_coding
description:
  D-alanyl-D-alanine carboxypeptidase (penicilin binding protein); Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.


ensembl_gene_id: BSU23490
symbol: pupG
gene_biotype: protein_coding
description:
  Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.


ensembl_gene_id: BSU23500
symbol: drm
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: BSU23520
symbol: fur
gene_biotype: protein_coding
description:
  Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes.


ensembl_gene_id: BSU23530
symbol: spoIIM
gene_biotype: protein_coding
description:
  Autolysin component for dissolution of the septal cell wall (stage II sporulation); Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.


ensembl_gene_id: BSU23550
symbol: mleA
gene_biotype: protein_coding
description:
  NAD-dependent malic enzyme (conversion of malate into pyruvate); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU23560
symbol: mleN
gene_biotype: protein_coding
description:
  malate-H+/Na+-lactate antiporter; Couples proton uptake and Na(+) efflux to the substrate- product malate/lactate antiport, in an electroneutral malate- 2H(+)/Na(+)-lactate exchange. Plays a role in supporting growth to high density on malate at reduced protonmotive force; Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter family.


ensembl_gene_id: BSU23570
symbol: ansB
gene_biotype: protein_coding
description:
  L-aspartase (aspartate ammonia lyase); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.


ensembl_gene_id: BSU23580
symbol: ansA
gene_biotype: protein_coding
description:
  Exported L-asparaginase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the asparaginase 1 family.


ensembl_gene_id: BSU23590
symbol: ansR
gene_biotype: protein_coding
description:
  Transcriptional regulator of ansAB (Xre family); Transcriptional repressor for the ans operon coding for L- asparaginase and L-aspartase. NH4(+) may influence this repression.


ensembl_gene_id: BSU23600
symbol: yqxK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To M.jannaschii MJ0043 N-terminal region.


ensembl_gene_id: BSU23610
symbol: nudF
gene_biotype: protein_coding
description:
  ADP-ribose pyrophosphatase; Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process (By similarity).


ensembl_gene_id: BSU23616
symbol: mciZ
gene_biotype: protein_coding
description:
  Cell division factor; Blocks Z-ring formation in the mother cell during sporulation by inhibiting the polymerization of FtsZ. Binds to the minus end of FtsZ and functions as a filament-capping protein. At high concentrations, is capable of both capping and sequestration of FtsZ. Decreases the GTPase activity of FtsZ.


ensembl_gene_id: BSU23620
symbol: yqkF
gene_biotype: protein_coding
description:
  NADPH-dependent aldo-keto reductase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.


ensembl_gene_id: BSU23670
symbol: yqkA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; In the C-terminal section; belongs to the UPF0157 (GrpB) family.


ensembl_gene_id: BSU23680
symbol: yqjZ
gene_biotype: protein_coding
description:
  Putative degradation enzyme (oxygenase); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU23690
symbol: yqjY
gene_biotype: protein_coding
description:
  Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU23700
symbol: yqjX
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951, 16267290.


ensembl_gene_id: BSU23710
symbol: polYB
gene_biotype: protein_coding
description:
  Y family DNA polymerase V bypassing lesions during replication; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).


ensembl_gene_id: BSU23760
symbol: coaA
gene_biotype: protein_coding
description:
  Pantothenate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type pe: putative enzyme.


ensembl_gene_id: BSU23770
symbol: dsdA
gene_biotype: protein_coding
description:
  D-serine ammonia-lyase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the serine/threonine dehydratase family. DsdA subfamily.


ensembl_gene_id: BSU23780
symbol: yqjQ
gene_biotype: protein_coding
description:
  Putative metabolite dehydrogenase, NAD-binding; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU23810
symbol: yqjN
gene_biotype: protein_coding
description:
  Putative N-deacylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis RocB.


ensembl_gene_id: BSU23820
symbol: yqjM
gene_biotype: protein_coding
description:
  NADPH-dependent flavin oxidoreductase; Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.


ensembl_gene_id: BSU23840
symbol: rnz
gene_biotype: protein_coding
description:
  Ribosomal protein L31C pseudogene; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.


ensembl_gene_id: BSU23850
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: BSU23860
symbol: gndA
gene_biotype: protein_coding
description:
  NADP+-dependent 6-P-gluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. Is the predominant 6-P-gluconate dehydrogenase isoenzyme in B.subtilis during growth on glucose and gluconate.


ensembl_gene_id: BSU23870
symbol: polYA
gene_biotype: protein_coding
description:
  DNA-damage lesion bypass DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII (By similarity).


ensembl_gene_id: BSU23880
symbol: mifM
gene_biotype: protein_coding
description:
  Regulator of OxaAB translation; Sensor protein that upregulates translation of the secondary membrane protein insertase (MisCB/YqjG) when activity of the primary membrane protein insertase (MisCA/SpoIIIJ) is limited. Acts as a ribosome-nascent chain complex. When the primary membrane protein insertase activity or level is reduced, the membrane insertion of MifM is impaired, which induces arrest of MifM translation and unfolding of the mRNA hairpin. Unfolding leads to translation of the downstream gene, which encodes the secondary membrane protein insertase MisCB/YqjG. Translation arres [...]


ensembl_gene_id: BSU23890
symbol: oxaAB
gene_biotype: protein_coding
description:
  Sec-independent factor for membrane protein insertion (YidC/SpoIIIJ family); Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity). Also involved in protein secretion processes. It has an overlapping, although partly distinct, function compared to SpoIIIJ(MisCB).


ensembl_gene_id: BSU23920
symbol: yqjD
gene_biotype: protein_coding
description:
  Putative propionyl-CoA carboxylase beta chain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU23930
symbol: yqjC
gene_biotype: protein_coding
description:
  Putative methylmalonyl-CoA epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the methylmalonyl-CoA epimerase family.


ensembl_gene_id: BSU23960
symbol: artR
gene_biotype: protein_coding
description:
  High affinity arginine ABC transporter (ATP-binding protein); Part of a binding-protein-dependent transport system for arginine. Probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU23970
symbol: artQ
gene_biotype: protein_coding
description:
  High affinity arginine ABC transporter (permease); Part of a binding-protein-dependent transport system for arginine. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU23980
symbol: artP
gene_biotype: protein_coding
description:
  High affinity arginine ABC transporter binding lipoprotein; Part of a binding-protein-dependent transport system for arginine.


ensembl_gene_id: BSU23990
symbol: yqiW
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0403 family.


ensembl_gene_id: BSU24000
symbol: bmrU
gene_biotype: protein_coding
description:
  Putative lipid kinase BmrU; May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro.


ensembl_gene_id: BSU24010
symbol: bmr
gene_biotype: protein_coding
description:
  Multidrug-efflux transporter; Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances, including such structurally diverse compounds as ethidium bromide, rhodamine and acridine dyes, tetraphenylphosphonium, puromycin, chloramphenicol, doxorubicin, and fluoroquinolone antibiotics; Belongs to the major facilitator superfamily. TCR/Tet family.


ensembl_gene_id: BSU24020
symbol: bmrR
gene_biotype: protein_coding
description:
  Transcriptional regulator (MerR family); Activates transcription of the bmr gene in response to structurally dissimilar drugs. Binds rhodamine as an inducer.


ensembl_gene_id: BSU24030
symbol: bkdB
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase E2 subunit (lipoamide acyltransferase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: BSU24040
symbol: bkdAB
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase E1 subunit; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: BSU24050
symbol: bkdAA
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase E1 subunit; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3); Belongs to the BCKDHA family.


ensembl_gene_id: BSU24060
symbol: lpdV
gene_biotype: protein_coding
description:
  Branched-chain alpha-keto acid dehydrogenase E3 subunit (dihydrolipoamide dehydrogenase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of 3 enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: BSU24070
symbol: buk
gene_biotype: protein_coding
description:
  Branched-chain fatty-acid kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the acetokinase family.


ensembl_gene_id: BSU24080
symbol: bcd
gene_biotype: protein_coding
description:
  Branched-chain amino acid dehydrogenase; Catalyzes the reversible deamination of L-leucine to 4- methyl-2-oxopentanoate.


ensembl_gene_id: BSU24090
symbol: ptb
gene_biotype: protein_coding
description:
  Phosphate butyryl coenzyme A transferase; Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate; Belongs to the phosphate acetyltransferase and butyryltransferase family.


ensembl_gene_id: BSU24100
symbol: bkdR
gene_biotype: protein_coding
description:
  Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU24120
symbol: mmgF
gene_biotype: protein_coding
description:
  2-methylisocitrate lyase; Involved in the methylcitric acid cycle. Catalyzes the cleavage of 2-methylisocitrate to yield pyruvate and succinate.


ensembl_gene_id: BSU24130
symbol: mmgE
gene_biotype: protein_coding
description:
  2-methylcitrate dehydratase; Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles. Has both 2-methylcitrate dehydratase and citrate dehydratase activities. Catalyzes the dehydration of 2-methylcitrate (2-MC) to yield 2-methyl-cis-aconitate, and the dehydration of citrate to yield cis-aconitate. Cannot form isocitrate. Uses either (2S,3R)- or (2R,3S)-2-methylcitrate.


ensembl_gene_id: BSU24140
symbol: mmgD
gene_biotype: protein_coding
description:
  2-methylcitrate synthase/citrate synthase III; Involved in both the tricarboxylic acid (TCA) and methylcitric acid cycles. Has both 2-methylcitrate synthase and citrate synthase activities. Catalyzes the condensation of propionyl-CoA and oxaloacetate to yield 2-methylcitrate (2-MC) and CoA, and the condensation of acetyl-CoA and oxaloacetate to yield citrate and CoA. Has 2.3-fold higher activity as a 2-methylcitrate synthase. Catalyzes the formation of either (2S,3R)- or (2R,3S)-2-methylcitrate.


ensembl_gene_id: BSU24150
symbol: mmgC
gene_biotype: protein_coding
description:
  Short chain acyl-CoA dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the acyl-CoA dehydrogenase family.


ensembl_gene_id: BSU24160
symbol: mmgB
gene_biotype: protein_coding
description:
  3-hydroxybutyryl-CoA dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: BSU24170
symbol: mmgA
gene_biotype: protein_coding
description:
  Degradative acetoacetyl-CoA thiolase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: BSU24180
symbol: yqiK
gene_biotype: protein_coding
description:
  Putative glycerophosphodiester phosphodiesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU24190
symbol: yqiI
gene_biotype: protein_coding
description:
  Putative N-acetylmuramoyl-L-alanine amidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family.


ensembl_gene_id: BSU24210
symbol: yqiG
gene_biotype: protein_coding
description:
  Putative NADH-dependent flavin oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.


ensembl_gene_id: BSU24220
symbol: spo0A
gene_biotype: protein_coding
description:
  Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box).


ensembl_gene_id: BSU24230
symbol: spoIVB
gene_biotype: protein_coding
description:
  Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter.


ensembl_gene_id: BSU24240
symbol: recN
gene_biotype: protein_coding
description:
  Factor for double strand breaks DNA repair and genetic recombination; Involved in recombinational repair of damaged DNA. Seems to be the first protein recruited to repair centers, foci that are the site of double-strand DNA break(s), followed by RecO and then RecF.


ensembl_gene_id: BSU24250
symbol: ahrC
gene_biotype: protein_coding
description:
  Transcriptional regulator; Represses the synthesis of biosynthetic enzymes and activates the arginine catabolism. Controls the transcription of the two operons rocABC and rocDEF.


ensembl_gene_id: BSU24260
symbol: yqxC
gene_biotype: protein_coding
description:
  Putative methyltransferase with RNA binding domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the TlyA family.


ensembl_gene_id: BSU24270
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: BSU24280
symbol: ispA
gene_biotype: protein_coding
description:
  Geranyltranstransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU24290
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII (small subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: BSU24300
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII (large subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: BSU24310
symbol: folD
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: BSU24320
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription termination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: BSU24340
symbol: accC
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase subunit (biotin carboxylase subunit); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: BSU24350
symbol: accB
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase subunit (biotin carboxyl carrier subunit); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA (By similarity). Binds biotin.


ensembl_gene_id: BSU24360
symbol: spoIIIAH
gene_biotype: protein_coding
description:
  Stage III sporulation ratchet engulfment protein; Involved in forespore engulfment. Forms a channel with SpoIIIAH that is open on the forespore end and closed (or gated) on the mother cell end. This allows sigma-E-directed gene expression in the mother-cell compartment of the sporangium to trigger the activation of sigma-G forespore-specific gene expression by a pathway of intercellular signaling.


ensembl_gene_id: BSU24370
symbol: spoIIIAG
gene_biotype: protein_coding
description:
  Stage III sporulation engulfment assembly protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU24380
symbol: spoIIIAF
gene_biotype: protein_coding
description:
  Stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU24390
symbol: spoIIIAE
gene_biotype: protein_coding
description:
  Stage III sporulation protein; Required during sporulation for activation of sigma factor SpoIIIG/SigG after engulfment is completed in the prespore. Overexpression in the absence of SpoIIIJ is synthetically lethal.


ensembl_gene_id: BSU24430
symbol: spoIIIAA
gene_biotype: protein_coding
description:
  ATP-binding stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU24450
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).


ensembl_gene_id: BSU24460
symbol: yqhT
gene_biotype: protein_coding
description:
  Putative aminopeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU24470
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase, type II; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU24520
symbol: mntR
gene_biotype: protein_coding
description:
  Transcriptional regulator (DtxR family); Central regulator of manganese homeostasis that regulates the expression of both manganese uptake and efflux systems. In the presence of high levels of manganese, it mediates repression of the manganese uptake systems MntH and MntABCD and activation of the efflux systems MneP and MneS. Binds with high affinity to the regulatory regions of its target genes. The manganese concentration required for activation of efflux is higher than that for repression of uptake ; Belongs to the DtxR/MntR family.


ensembl_gene_id: BSU24530
symbol: lipM
gene_biotype: protein_coding
description:
  Protein octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. Is also able to catalyze the reverse reaction. Octanoyl-CoA can also act as a substrate although very poorly. Does not display lipoate protein ligase activity, despite its sequence similarity to LplA; Belongs to the octanoyltransferase LipM family.


ensembl_gene_id: BSU24540
symbol: yqhL
gene_biotype: protein_coding
description:
  Putative sulfur transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU24550
symbol: gcvPB
gene_biotype: protein_coding
description:
  Glycine decarboxylase (subunit 2) (glycine cleavage system protein P); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity); Belongs to the GcvP family. C-terminal subunit subfamily.


ensembl_gene_id: BSU24560
symbol: gcvPA
gene_biotype: protein_coding
description:
  Glycine decarboxylase (subunit 1) (glycine cleavage system protein P); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).


ensembl_gene_id: BSU24570
symbol: gcvT
gene_biotype: protein_coding
description:
  Aminomethyltransferase (glycine cleavage system protein T); The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: BSU24580
symbol: yqhH
gene_biotype: protein_coding
description:
  Putative RNA polymerase-associated helicase protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the SNF2/RAD54 helicase family.


ensembl_gene_id: BSU24600
symbol: sinI
gene_biotype: protein_coding
description:
  Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE.


ensembl_gene_id: BSU24610
symbol: sinR
gene_biotype: protein_coding
description:
  Master regulator of biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swarm and a state in which bacteria assemb [...]


ensembl_gene_id: BSU24620
symbol: tasA
gene_biotype: protein_coding
description:
  Major biofilm matrix component; TasA is the major protein component of the biofilm extracellular matrix. It forms amyloid fibers that bind cells together in the biofilm. Exhibits an antibacterial activity against a variety of Gram-positive and Gram-negative bacteria. In laboratory strains, is also involved in proper spore coat assembly.


ensembl_gene_id: BSU24630
symbol: sipW
gene_biotype: protein_coding
description:
  Type I signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation. Belongs to the peptidase S26B family.


ensembl_gene_id: BSU24640
symbol: tapA
gene_biotype: protein_coding
description:
  Lipoprotein for biofilm formation; Required for biofilm formation. Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface. Is also a minor component of TasA fibers.


ensembl_gene_id: BSU24710
symbol: comGC
gene_biotype: protein_coding
description:
  Pilin-like component of the DNA transport membrane platform; Required for transformation and DNA binding. Belongs to the ComGC family.


ensembl_gene_id: BSU24720
symbol: comGB
gene_biotype: protein_coding
description:
  Membrane platform component of the DNA transport machinery; Required for transformation and DNA binding. Belongs to the GSP F family.


ensembl_gene_id: BSU24740
symbol: yqxL
gene_biotype: protein_coding
description:
  Putative CorA-type Mg(2+) transporter; Mediates influx of magnesium ions. Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high. May also mediate uptake of Co(2+).


ensembl_gene_id: BSU24750
symbol: yqhB
gene_biotype: protein_coding
description:
  Putative membrane associated protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU24770
symbol: mgsR
gene_biotype: protein_coding
description:
  Transcriptional regulator of stress; Regulates transcription of a subregulon within the general stress response. Exerts positive and negative effects in response to ethanol stress.


ensembl_gene_id: BSU24790
symbol: yqgX
gene_biotype: protein_coding
description:
  Putative metal-binding hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU24810
symbol: yqgV
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0045 family.


ensembl_gene_id: BSU24830
symbol: yqgT
gene_biotype: protein_coding
description:
  Putative gamma-D-glutamyl-L-diamino acid endopeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase M14 family.


ensembl_gene_id: BSU24840
symbol: ltaSC
gene_biotype: protein_coding
description:
  Enzyme responsible for polyglycerolphosphate LTA synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the LTA synthase family.


ensembl_gene_id: BSU24850
symbol: glcK
gene_biotype: protein_coding
description:
  Glucose kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the ROK (NagC/XylR) family.


ensembl_gene_id: BSU24860
symbol: yqgQ
gene_biotype: protein_coding
description:
  Putative single strand nucleic acid binding transcription factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU24870
symbol: glpG
gene_biotype: protein_coding
description:
  Membrane endopeptidase; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter.


ensembl_gene_id: BSU24890
symbol: folN
gene_biotype: protein_coding
description:
  5-formyltetrahydrofolate cyclo-ligase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: BSU24900
symbol: rpmGA
gene_biotype: protein_coding
description:
  Ribosomal protein L33; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: BSU24910
symbol: yqgM
gene_biotype: protein_coding
description:
  Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.


ensembl_gene_id: BSU24950
symbol: pstBB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter (ATP-binding protein); Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: BSU24970
symbol: pstA
gene_biotype: protein_coding
description:
  Phosphate ABC transporter (permease); Part of the binding-protein-dependent transport system YqgGHIJK. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BSU24990
symbol: pstS
gene_biotype: protein_coding
description:
  Phosphate ABC transporter (binding lipoprotein); Part of the ABC transporter complex PstSACB involved in phosphate import.


ensembl_gene_id: BSU25000
symbol: pbpA
gene_biotype: protein_coding
description:
  Transpeptidase (penicillin-binding protein 2A); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU25020
symbol: sodA
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: BSU25040
symbol: yqgB
gene_biotype: protein_coding
description:
  Factor involved in motility; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type ph: phenotype.


ensembl_gene_id: BSU25070
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin); Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: BSU25090
symbol: yqfW
gene_biotype: protein_coding
description:
  Putative nucleotidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the 5'(3')-deoxyribonucleotidase family.


ensembl_gene_id: BSU25100
symbol: zur
gene_biotype: protein_coding
description:
  Transcriptional regulator (Fur family); Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes. Required for the zinc-specific repression of two operons implicated in zinc uptake, yciC and ycdHIyceA. Also represses the expression of rpmE2, the gene for ribosomal protein L31B, which is expressed only after the end of exponential growth.


ensembl_gene_id: BSU25130
symbol: nfo
gene_biotype: protein_coding
description:
  Type IV apurinic/apyrimidinic endonuclease; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.


ensembl_gene_id: BSU25140
symbol: cshB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase that plays a role in 70S ribosome assembly. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures.


ensembl_gene_id: BSU25160
symbol: ispH
gene_biotype: protein_coding
description:
  1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: BSU25180
symbol: trmK
gene_biotype: protein_coding
description:
  tRNA (adenine(22)-N(1))-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 22 (m1A22) in tRNA.


ensembl_gene_id: BSU25200
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase major sigma-43 factor (sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth; Belongs to the sigma-70 factor family. RpoD/SigA subfamily.


ensembl_gene_id: BSU25210
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: BSU25220
symbol: antE
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 9864351.


ensembl_gene_id: BSU25230
symbol: yqxD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9387153; Belongs to the UPF0178 family.


ensembl_gene_id: BSU25240
symbol: yqfL
gene_biotype: protein_coding
description:
  Positive regulator of gluconeogenesis; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: BSU25250
symbol: ccpN
gene_biotype: protein_coding
description:
  Negative regulator of gluconeogenesis; Transcription repressor that binds to the promoter of gapB and pckA genes, preventing their expression. Acts as a regulator for catabolite repression of gluconeogenic genes.


ensembl_gene_id: BSU25260
symbol: glyS
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase (beta subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU25270
symbol: glyQ
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase (alpha subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU25280
symbol: recO
gene_biotype: protein_coding
description:
  DNA double strand break repair and homologous recombination factor; Plays a role in DNA double-stranded break repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecR. Is recruited to repair centers, foci that are the site of double-strand break(s) after RecN and before RecF; may actively recruit RecF.


ensembl_gene_id: BSU25290
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity). Binds both GDP and GTP. Complements an E.coli era disruption mutant; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.


ensembl_gene_id: BSU25300
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine/deoxycytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: BSU25310
symbol: dgkA
gene_biotype: protein_coding
description:
  Undecaprenol kinase; Catalyzes the phosphorylation of undecaprenol in vitro, which is probably the physiological substrate. Exhibits no detectable activity against other substrates such as monoacylglycerol, ceramide, or diacylglycerol (DAG). Appears indispensable for the maintenance of spore stability and viability in B.subtilis.


ensembl_gene_id: BSU25320
symbol: yqfG
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: BSU25330
symbol: yqfF
gene_biotype: protein_coding
description:
  Putative membrane associate hydrolase; Probably has phosphodiesterase (PDE) activity against cyclic- di-AMP (c-di-AMP); may be the major c-di-AMP PDE in the cell. In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess.


ensembl_gene_id: BSU25340
symbol: phoH
gene_biotype: protein_coding
description:
  Phosphate starvation-induced protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.


ensembl_gene_id: BSU25350
symbol: yqfD
gene_biotype: protein_coding
description:
  Stage IV sporulation protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process.


ensembl_gene_id: BSU25360
symbol: yqfC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12662922.


ensembl_gene_id: BSU25380
symbol: yqfA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type cp: cell process.


ensembl_gene_id: BSU25390
symbol: yqeZ
gene_biotype: protein_coding
description:
  Putative membrane bound hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU25410
symbol: rpsU
gene_biotype: protein_coding
description:
  Ribosomal protein S21; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type s: structure; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: BSU25420
symbol: yqeW
gene_biotype: protein_coding
description:
  Putative Na+/anion cotransporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU25430
symbol: mtaB
gene_biotype: protein_coding
description:
  tRNA N(6)-threonylcarbamoyladenosine (t(6)A) methylthiotransferase; Catalyzes the methylthiolation of N6- threonylcarbamoyladenosine (t(6)A), leading to the formation of 2- methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. Belongs to the methylthiotransferase family. MtaB subfamily.


ensembl_gene_id: BSU25440
symbol: rsmE
gene_biotype: protein_coding
description:
  Methylase of U1498 in 16S rRNA; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).


ensembl_gene_id: BSU25450
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: BSU25460
symbol: dnaJ
gene_biotype: protein_coding
description:
  Co-factor of molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...]


ensembl_gene_id: BSU25480
symbol: grpE
gene_biotype: protein_coding
description:
  Nucleotide exchange factor for DnaK activity; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. S [...]


ensembl_gene_id: BSU25490
symbol: hrcA
gene_biotype: protein_coding
description:
  Transcriptional regulator of heat-shock genes; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: BSU25500
symbol: hemN
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently (By similarity). Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine (By similarity).


ensembl_gene_id: BSU25510
symbol: lepA
gene_biotype: protein_coding
description:
  Ribosomal elongation factor, GTPase; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: BSU25530
symbol: spoIIP
gene_biotype: protein_coding
description:
  Spore autolysin (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU25540
symbol: gpr
gene_biotype: protein_coding
description:
  Spore endopeptidase; Initiates the degradation of small, acid-soluble proteins during spore germination.


ensembl_gene_id: BSU25550
symbol: rpsT
gene_biotype: protein_coding
description:
  Ribosomal protein S20 (BS20); Binds directly to 16S ribosomal RNA; Belongs to the bacterial ribosomal protein bS20 family.


ensembl_gene_id: BSU25560
symbol: holA
gene_biotype: protein_coding
description:
  DNA polymerase delta subunit; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.


ensembl_gene_id: BSU25570
symbol: comEC
gene_biotype: protein_coding
description:
  DNA channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding; To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI.


ensembl_gene_id: BSU25580
symbol: comEB
gene_biotype: protein_coding
description:
  Putative enzyme associated to DNA transport (competence); Dispensable for transformability; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: BSU25590
symbol: comEA
gene_biotype: protein_coding
description:
  Membrane bound high-affinity DNA-binding receptor; Needed for both DNA binding and transport. It is absolutely required for the uptake of transforming DNA but not for binding. Its role in binding may be indirect.


ensembl_gene_id: BSU25600
symbol: comER
gene_biotype: protein_coding
description:
  Putative pyrroline-5'-carboxylate reductase; Dispensable for transformability. Not known if it can act as a pyrroline-5-carboxylate reductase.


ensembl_gene_id: BSU25620
symbol: rsfS
gene_biotype: protein_coding
description:
  Ribosomal silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: BSU25640
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD); Belongs to the NadD family.


ensembl_gene_id: BSU25650
symbol: yqeI
gene_biotype: protein_coding
description:
  Putative RNA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU25660
symbol: aroD
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: BSU25690
symbol: sda
gene_biotype: protein_coding
description:
  Check point factor coupling initiation of sporulation and replication initiation; Mediates a developmental checkpoint inhibiting initiation of sporulation (by preventing phosphorylation of spo0A) in response to defects in the replication initiation machinery. Inhibits autophosphorylation of the histidine protein kinase KinA, forming a molecular barricade that prevents productive interaction between the ATP-binding site in the catalytic domain and the phosphorylatable His in the phosphotransfer domain of KinA. Probably also inhibits the activity of KinB, but has relatively little effect [...]


ensembl_gene_id: BSU25700
symbol: yqeF
gene_biotype: protein_coding
description:
  Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU25710
symbol: cwlH
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Could play a role in mother cell lysis with CwlC; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.


ensembl_gene_id: BSU25720
symbol: yqeD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 15855514, 16850406.


ensembl_gene_id: BSU25750
symbol: nucB
gene_biotype: protein_coding
description:
  Nuclease; Degrades both double-stranded linear and covalently closed circular DNA. Likely to play a scavenging role in order to supply nutrients under starvation conditions; To B.subtilis NucA/ComI.


ensembl_gene_id: BSU25770
symbol: spoIVCA
gene_biotype: protein_coding
description:
  RNA polymerase sporulation-specific sigma-K factor precursor (Sigma-27) (N-terminal half); Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of SpoIIIC and SpoIVCB to form sigma K factor.


ensembl_gene_id: BSU25780
symbol: arsC
gene_biotype: protein_coding
description:
  Thioredoxin-coupled arsenate reductase; Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. In vitro, can dephosphorylate para- nitrophenyl phosphate (pNPP). Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.


ensembl_gene_id: BSU25790
symbol: arsB
gene_biotype: protein_coding
description:
  Arsenite efflux transporter; Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump.


ensembl_gene_id: BSU25800
symbol: yqcK
gene_biotype: protein_coding
description:
  Putative thiol lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To M.tuberculosis Rv2641.


ensembl_gene_id: BSU25820
symbol: yqcI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin; Belongs to the DcsA family.


ensembl_gene_id: BSU25830
symbol: rapE
gene_biotype: protein_coding
description:
  Response regulator aspartate phosphatase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type r: regulator; Belongs to the RAP family.


ensembl_gene_id: BSU25860
symbol: rttG
gene_biotype: protein_coding
description:
  Phage ribonuclease toxin; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 379-531) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YqcF, but not by antitoxins specific to other toxins with the LXG domain.


ensembl_gene_id: BSU25870
symbol: rttF
gene_biotype: protein_coding
description:
  Antitoxin factor of ribonuclease toxin RttG; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the RNase activity of cognate toxin YqcG, as well as its ability to inhibit growth upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain.


ensembl_gene_id: BSU25900
symbol: cwlA
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation; Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.


ensembl_gene_id: BSU25910
symbol: yqxH
gene_biotype: protein_coding
description:
  Putative holin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU25920
symbol: yqxG
gene_biotype: protein_coding
description:
  Putative phage-related lytic exoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis XkdY/XepA.


ensembl_gene_id: BSU25930
symbol: yqcE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdX.


ensembl_gene_id: BSU25940
symbol: yqcD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdW.


ensembl_gene_id: BSU25950
symbol: yqcC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; To B.subtilis XkdV.


ensembl_gene_id: BSU25970
symbol: yqcA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; To B.subtilis XkdU.


ensembl_gene_id: BSU25980
symbol: yqbT
gene_biotype: protein_coding
description:
  Putative phage capsid assembly protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure; Belongs to the Mu gp47/PBSX XkdT family.


ensembl_gene_id: BSU25990
symbol: yqbS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdS.


ensembl_gene_id: BSU26000
symbol: yqbR
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdR.


ensembl_gene_id: BSU26010
symbol: yqbQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdQ.


ensembl_gene_id: BSU26030
symbol: yqbO
gene_biotype: protein_coding
description:
  Putative lytic transglycosylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis XkdO.


ensembl_gene_id: BSU26050
symbol: txpA
gene_biotype: protein_coding
description:
  Conserved unknown protein (fragment); Toxic component of a type I toxin-antitoxin (TA) system. Overexpression of txpA causes cell lysis; the TxpA protein has been suggested to act on the cell membrane or might possibly block cell wall synthesis. Overexpression in E.coli is not toxic.


ensembl_gene_id: BSU26060
symbol: yqbM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; To B.subtilis XkdM.


ensembl_gene_id: BSU26075
symbol: yqbK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the myoviridae tail sheath protein family.


ensembl_gene_id: BSU26090
symbol: yqbJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdJ.


ensembl_gene_id: BSU26100
symbol: yqbI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdI.


ensembl_gene_id: BSU26110
symbol: yqbH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XkdH.


ensembl_gene_id: BSU26140
symbol: yqbE
gene_biotype: protein_coding
description:
  Putative phage capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure; To B.subtilis XkdG.


ensembl_gene_id: BSU26170
symbol: yqbB
gene_biotype: protein_coding
description:
  Putative phage head morphogenesis protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.


ensembl_gene_id: BSU26190
symbol: yqaT
gene_biotype: protein_coding
description:
  Putative phage-related terminase large subunit; May function as a terminase; To B.subtilis XtmB and phage SPP1 terminase large subunit.


ensembl_gene_id: BSU26200
symbol: yqaS
gene_biotype: protein_coding
description:
  Putative phage-related terminase small subunit; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU26220
symbol: yqaQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis pcf and to sigma factors.


ensembl_gene_id: BSU26240
symbol: yqaO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis XtrA.


ensembl_gene_id: BSU26250
symbol: yqaN
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU26260
symbol: yqaM
gene_biotype: protein_coding
description:
  Putative replication-related ATPase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis YqxC and T.hyodysenteriae hemolysin TlyA.


ensembl_gene_id: BSU26270
symbol: yqaL
gene_biotype: protein_coding
description:
  Putative DNA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU26280
symbol: yqaK
gene_biotype: protein_coding
description:
  Putative DNA recombination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU26290
symbol: yqaJ
gene_biotype: protein_coding
description:
  Putative nuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU26370
symbol: yqaC
gene_biotype: protein_coding
description:
  Putative kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU26400
symbol: yrkS
gene_biotype: protein_coding
description:
  RNA polymerase sporulation-specific sigma-K factor precursor (Sigma-27) (C-terminal fragment); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU26410
symbol: psiE
gene_biotype: protein_coding
description:
  Phosphate starvation inducible protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; membrane component.


ensembl_gene_id: BSU26420
symbol: yrkQ
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YrkP]; Member of the two-component regulatory system YrkQ/YrkP. Probably activates YrkP by phosphorylation.


ensembl_gene_id: BSU26450
symbol: yrkN
gene_biotype: protein_coding
description:
  Putative N-acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU26470
symbol: yrkL
gene_biotype: protein_coding
description:
  Putative NAD(P)H oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the NAD(P)H dehydrogenase (quinone) family.


ensembl_gene_id: BSU26500
symbol: yrkI
gene_biotype: protein_coding
description:
  Putative sulfur-carrier protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: BSU26530
symbol: yrkF
gene_biotype: protein_coding
description:
  Putative rhodanese-related sulfur transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: BSU26580
symbol: bltR
gene_biotype: protein_coding
description:
  Transcriptional regulator; Activates transcription of the blt gene in response to structurally dissimilar drugs.


ensembl_gene_id: BSU26590
symbol: blt
gene_biotype: protein_coding
description:
  Efflux transporter; Energy-dependent efflux pump responsible for decreased drug accumulation in multi-drug-resistant cells. Probably uses a transmembrane proton gradient as the energy source. Causes the efflux of a variety of toxic substances, including such structurally diverse compounds as ethidium bromide, rhodamine and acridine dyes, tetraphenylphosphonium, puromycin, chloramphenicol, doxorubicin, and fluoroquinolone antibiotics; Belongs to the major facilitator superfamily. TCR/Tet family.


ensembl_gene_id: BSU26600
symbol: bltD
gene_biotype: protein_coding
description:
  Spermine/spermidine acetyltransferase; Acetylates both spermidine and spermine at primary propyl amine moieties, with spermine being the preferred substrate.


ensembl_gene_id: BSU26610
symbol: yrkA
gene_biotype: protein_coding
description:
  Putative membrane associated protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.


ensembl_gene_id: BSU26640
symbol: yrdP
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Involved in potassium and divalent cation transport. Enhances the transport activity of the cation/potassium transporter CzcD.


ensembl_gene_id: BSU26650
symbol: czcD
gene_biotype: protein_coding
description:
  Potassium/proton-divalent cation antiporter; Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions.


ensembl_gene_id: BSU26670
symbol: gltR
gene_biotype: protein_coding
description:
  Transcriptional regulator (LysR family); Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: BSU26690
symbol: brnQ
gene_biotype: protein_coding
description:
  Low-affinity branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force.


ensembl_gene_id: BSU26700
symbol: azlD
gene_biotype: protein_coding
description:
  Branched-chain amino acid transporter; Involved in branched-chain amino acid transport; Belongs to the AzlD/HI_1737/HP1330 family.


ensembl_gene_id: BSU26710
symbol: azlC
gene_biotype: protein_coding
description:
  Branched-chain amino acid transporter; Involved in branched-chain amino acid transport; Belongs to the AzlC family.


ensembl_gene_id: BSU26720
symbol: azlB
gene_biotype: protein_coding
description:
  Transcriptional regulator (Lrp/AsnC family); Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport.


ensembl_gene_id: BSU26730
symbol: yrdF
gene_biotype: protein_coding
description:
  Putative ribonuclease inhibitor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU26740
symbol: cypA
gene_biotype: protein_coding
description:
  Cytochrome P450; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU26790
symbol: aadK
gene_biotype: protein_coding
description:
  Aminoglycoside 6-adenylyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; To E.faecalis AadE.


ensembl_gene_id: BSU26800
symbol: yrpB
gene_biotype: protein_coding
description:
  Putative anionic nitroalkane dioxygenase; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism.


ensembl_gene_id: BSU26820
symbol: yrpD
gene_biotype: protein_coding
description:
  Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; To B.subtilis YncM.


ensembl_gene_id: BSU26826
symbol: yrpDX
gene_biotype: protein_coding
description:
  Expressed polypeptide of unknown function; Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 20709900.


ensembl_gene_id: BSU26830
symbol: yrpE
gene_biotype: protein_coding
description:
  Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; Belongs to the calycin superfamily. ZinT family.


ensembl_gene_id: BSU26840
symbol: sigZ
gene_biotype: protein_coding
description:
  RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma-Z); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: BSU26860
symbol: yraO
gene_biotype: protein_coding
description:
  Putative citrate transporter; Transports the free citrate anion; Belongs to the CitM (TC 2.A.11) transporter family.


ensembl_gene_id: BSU26880
symbol: yraM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the PrpF family.


ensembl_gene_id: BSU26890
symbol: csn
gene_biotype: protein_coding
description:
  Chitosanase; Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.


ensembl_gene_id: BSU26920
symbol: yraJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YraI.


ensembl_gene_id: BSU26930
symbol: yraI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; To B.subtilis YraJ.


ensembl_gene_id: BSU26940
symbol: yraH
gene_biotype: protein_coding
description:
  Putative lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glyoxalase I family.


ensembl_gene_id: BSU26950
symbol: yraG
gene_biotype: protein_coding
description:
  Putative spore coat protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; cell process.


ensembl_gene_id: BSU26970
symbol: adhB
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: BSU27000
symbol: yraB
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (MerR family); Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes.


ensembl_gene_id: BSU27009
symbol: yrzP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17962296.


ensembl_gene_id: BSU27010
symbol: adhA
gene_biotype: protein_coding
description:
  Putative dehydrogenase; Functions in the protection against aldehyde-stress. Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: BSU27020
symbol: yraA
gene_biotype: protein_coding
description:
  General stress protein; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins.


ensembl_gene_id: BSU27030
symbol: sacC
gene_biotype: protein_coding
description:
  Levanase; Exo-fructosidase that can hydrolyze both levan and inulin, leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose, but not melezitose, stachylose, cellobiose, maltose, and lactose.


ensembl_gene_id: BSU27040
symbol: levG
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) fructose-specific enzyme IID component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport.


ensembl_gene_id: BSU27050
symbol: levF
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) fructose-specific enzyme IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system is involved in fructose transport.


ensembl_gene_id: BSU27060
symbol: levE
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) fructose-specific enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LevDE PTS system is involved in fructose transport.


ensembl_gene_id: BSU27070
symbol: levD
gene_biotype: protein_coding
description:
  Phosphotransferase system (PTS) fructose-specific enzyme IIA component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LevDE PTS system is involved in fructose transport.


ensembl_gene_id: BSU27080
symbol: levR
gene_biotype: protein_coding
description:
  Transcriptional regulator (NifA/NtrC family); Involved in positive regulation of the levanase operon which comprises the levDEFG genes for a fructose PTS system, and sacA for levanase.


ensembl_gene_id: BSU27090
symbol: aapA
gene_biotype: protein_coding
description:
  d-Serine/d-alanine/glycine permease; Probable amino-acid or metabolite transport protein; Belongs to the amino acid-polyamine-organocation (APC) superfamily.


ensembl_gene_id: BSU27120
symbol: sigV
gene_biotype: protein_coding
description:
  RNA polymerase ECF(extracytoplasmic function)-type sigma factor (sigma(V)); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Positively regulates the expression of proteins involved in stress responses against bacitracin, paraquat and tellurite. Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: BSU27130
symbol: rsiV
gene_biotype: protein_coding
description:
  anti-sigma(V) factor; Anti-sigma factor for SigV. Negatively regulates SigV activity through direct interaction.


ensembl_gene_id: BSU27140
symbol: oatA
gene_biotype: protein_coding
description:
  Peptidoglycan O-acetyltransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme.


ensembl_gene_id: BSU27160
symbol: cypB
gene_biotype: protein_coding
description:
  Cytochrome P450 CYP102A3; Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of a range of medium to long-chain fatty acids, with a preference for long-chain unsaturated and branched-chain fatty acids over saturated fatty acids. Hydroxylation of myristic acid occurs mainly at the omega-2 and omega-3 positions, in approximately equal proportions. Also displays a NADPH-dependent reductase activity in the C-terminal domain, which allows electron transfer from NADPH to the heme iron of the cytochrome P450 N-terminal domain.


ensembl_gene_id: BSU27170
symbol: bscR
gene_biotype: protein_coding
description:
  Transcriptional regulator for cypB; Negatively regulates the transcription of the fatR-cypB operon. Is displaced from its operator by a range of fatty acids such as oleate, linoleate and phytanate, thereby allowing transcription of the fatR-cypB operon.


ensembl_gene_id: BSU27200
symbol: yrhG
gene_biotype: protein_coding
description:
  Putative formate/nitrite transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU27220
symbol: yrhE
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: BSU27230
symbol: yrhD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079; To A.fulgidus AF1717.


ensembl_gene_id: BSU27240
symbol: yrhC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17056751.


ensembl_gene_id: BSU27250
symbol: mccB
gene_biotype: protein_coding
description:
  Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Catalyzes the conversion of cystathionine to cysteine, and homocysteine to sulfide.


ensembl_gene_id: BSU27260
symbol: mccA
gene_biotype: protein_coding
description:
  Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine.


ensembl_gene_id: BSU27270
symbol: mtnN
gene_biotype: protein_coding
description:
  Methylthioadenosine / S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: BSU27280
symbol: yrrT
gene_biotype: protein_coding
description:
  Putative AdoMet-dependent methyltransferase; Could be a S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the methyltransferase superfamily. YrrT family.


ensembl_gene_id: BSU27300
symbol: yrrS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14679248.


ensembl_gene_id: BSU27310
symbol: pbpI
gene_biotype: protein_coding
description:
  Penicillin-binding protein PBP4B; Penicillin-binding protein with an unknown catalytic activity. Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Beta-lactamase inactivates the PBPs by acylating an essential serine residue in the active site of these proteins, thereby interrupting normal cell wall synthesis; Belongs to the transpeptidase family.


ensembl_gene_id: BSU27320
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity); Belongs to the GreA/GreB family.


ensembl_gene_id: BSU27340
symbol: yrrO
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase U32 family.


ensembl_gene_id: BSU27360
symbol: yrrM
gene_biotype: protein_coding
description:
  Putative acyl-CoA O-methyltransferase; Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.


ensembl_gene_id: BSU27370
symbol: yrrL
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: BSU27380
symbol: yrzB
gene_biotype: protein_coding
description:
  Putative anti-sigma factor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs to the UPF0473 family.


ensembl_gene_id: BSU27390
symbol: yrrK
gene_biotype: protein_coding
description:
  Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.


ensembl_gene_id: BSU27400
symbol: yrzL
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0297 family.


ensembl_gene_id: BSU27410
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: BSU27430
symbol: glnQ
gene_biotype: protein_coding
description:
  Glutamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for energy coupling to the transport system (By similarity).


ensembl_gene_id: BSU27440
symbol: glnH
gene_biotype: protein_coding
description:
  Glutamine ABC transporter (glutamine-binding lipoprotein); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: BSU27450
symbol: glnM
gene_biotype: protein_coding
description:
  Glutamine ABC transporter (permease); Part of the ABC transporter complex GlnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: BSU27480
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V alpha chain; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.


ensembl_gene_id: BSU27490
symbol: yrrB
gene_biotype: protein_coding
description:
  Putative tetratricopeptide repeat family protein; Could be an interacting mediator in the complex formation among RNA sulfuration components, RNA processing components, and aminoacyl-tRNA synthetases.


ensembl_gene_id: BSU27500
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: BSU27510
symbol: iscSA
gene_biotype: protein_coding
description:
  Cysteine desulfurase involved in tRNA thiolation; Catalyzes the removal of elemental sulfur from cysteine to produce alanine.


ensembl_gene_id: BSU27520
symbol: cymR
gene_biotype: protein_coding
description:
  Transcriptional regulator of cysteine biosynthesis; Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulated by CysK in response to cysteine availability. When cysteine is present, the pool of O-acetylserine (OAS) is low, which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine, the OAS pool is high and the Cy [...]


ensembl_gene_id: BSU27530
symbol: rarA
gene_biotype: protein_coding
description:
  DNA-dependent ATPase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.


ensembl_gene_id: BSU27540
symbol: yrvM
gene_biotype: protein_coding
description:
  Putative factor involved in sulfur-containing coenzyme synthesis; Catalyzes the ATP-dependent dehydration of threonylcarbamoyladenosine at position 37 (t(6)A37) to form cyclic t(6)A37 (ct(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: BSU27550
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: BSU27560
symbol: hisS
gene_biotype: protein_coding
description:
  histidyl-tRNA synthetase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU27600
symbol: rsh
gene_biotype: protein_coding
description:
  GTP pyrophosphokinase (RelA/SpoT); In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp, it is probably the hydrolysis activity that is required for optimal growth (Probable); Belongs to the RelA/SpoT family.


ensembl_gene_id: BSU27610
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: BSU27620
symbol: recJ
gene_biotype: protein_coding
description:
  Putative single-strand DNA-specific exonuclease; Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB; Belongs to the RecJ family.


ensembl_gene_id: BSU27640
symbol: yrvC
gene_biotype: protein_coding
description:
  Putative potassium transport accessory component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: BSU27650
symbol: secDF
gene_biotype: protein_coding
description:
  Protein-export membrane protein; Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane. In the N-terminal section; belongs to the SecD/SecF family. SecD subfamily.


ensembl_gene_id: BSU27660
symbol: comN
gene_biotype: protein_coding
description:
  Post-transcriptional regulator; Required for post-transcription initiation control of the comE operon. Promotes the accumulation of its target comE mRNA to septal and polar sites.


ensembl_gene_id: BSU27670
symbol: spoVB
gene_biotype: protein_coding
description:
  Putative putative translocase with flippase function for teichoic acid synthesis; Involved, directly or indirectly, in spore cortex biosynthesis. Affects only indirectly the expression of late sporulation genes.


ensembl_gene_id: BSU27700
symbol: yrbF
gene_biotype: protein_coding
description:
  Component of the preprotein translocase; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: BSU27710
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the  [...]


ensembl_gene_id: BSU27720
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: BSU27730
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase, ATP-dependent component; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity). Stimulates the resolution of Holliday junctions by RecU.


ensembl_gene_id: BSU27740
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: BSU27750
symbol: bofC
gene_biotype: protein_coding
description:
  Bypass of forespore C, intercompartmental signaling factor; Inhibits the SpoIVB zymogen from undergoing autocatalytic activation by an unknown mechanism, and in this way plays a role in the sigma-K checkpoint of sporulation.


ensembl_gene_id: BSU27760
symbol: csbX
gene_biotype: protein_coding
description:
  Putative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. CsbX subfamily.


ensembl_gene_id: BSU27785
symbol: yrzF
gene_biotype: protein_coding
description:
  Putative serine/threonine-protein kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.


ensembl_gene_id: BSU27810
symbol: yrbD
gene_biotype: protein_coding
description:
  Sodium/proton-dependent alanine transporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: BSU27830
symbol: coxA
gene_biotype: protein_coding
description:
  Spore cortex protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type f: factor.


ensembl_gene_id: BSU27840
symbol: safA
gene_biotype: protein_coding
description:
  Morphogenetic protein associated with SpoVID; Probably involved in the assembly of some coat protein components implicated in both lysozyme resistance and germination. Could be required for the assembly of CotG. Associates with SpoIVD during the early stage of coat assembly.


ensembl_gene_id: BSU27850
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: BSU27880
symbol: nifS
gene_biotype: protein_coding
description:
  Putative desulfurase involved in iron-sulfur clusters for NAD biosynthesis; Catalyzes the removal of elemental sulfur from cysteine to produce alanine (By similarity). Seems to be required for NAD biosynthesis.


ensembl_gene_id: BSU27890
symbol: niaR
gene_biotype: protein_coding
description:
  Transcriptional repressor of de novo NAD biosynthesis; In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene, probably regulating it as well. May bind nicotinic acid.


ensembl_gene_id: BSU27900
symbol: pheA
gene_biotype: protein_coding
description:
  Prephenate dehydratase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU27910
symbol: yszB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein containing an ACT domain; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 2537815; Belongs to the UPF0735 family.


ensembl_gene_id: BSU27920
symbol: obg
gene_biotype: protein_coding
description:
  GTPase involved in cell partioning and DNA repair; Necessary for the transition from vegetative growth to stage 0 or stage II of sporulation, but sporulation subsequent to these stages is unaffected at 45 degrees Celsius. This ts effect is probably due solely to the E-79 mutation. Required for expression of early sporulation genes, further suggesting a role in the induction of sporulation. Depletion effects on sporulation can be partially suppressed by missense mutations in spo0A. Strains depleted for obg stop growing after about 3 hours and do not induce the sigma-B factor following e [...]


ensembl_gene_id: BSU27930
symbol: spo0B
gene_biotype: protein_coding
description:
  Sporulation initiation phosphotransferase; Key element in the phosphorelay regulating sporulation initiation. Acts on spo0A. Mediates reversible phosphoryl transfer from spo0F to spo0A.


ensembl_gene_id: BSU27950
symbol: ysxB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11567142; To M.genitalium MG233.


ensembl_gene_id: BSU27960
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21 (BL20); This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: BSU27970
symbol: spoIVFB
gene_biotype: protein_coding
description:
  Membrane metalloprotease; Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation. Processes the pro-sigma K factor.


ensembl_gene_id: BSU27980
symbol: spoIVFA
gene_biotype: protein_coding
description:
  Regulator of SpoIVFB (stage IV sporulation); Implicated in the coupling of mother cell to forespore gene expression. Required for spore formation at 37 degrees Celsius, but not at 30 degrees Celsius. SpoIVFA plays a central role in both maintaining the SpoIVFA/BofA/SpoIVFB complex and anchoring it to the outer forespore membrane. SpoIVFA brings BofA into close proximity to SpoIVFB, allowing BofA to inhibit SpoIVFB. Increased accumulation of SpoIVFA seems to inhibit the activity of SpoIVFB and thus regulates the activation of sigma-K.


ensembl_gene_id: BSU27990
symbol: minD
gene_biotype: protein_coding
description:
  ATPase activator of MinC; ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity); Belongs to the ParA family. MinD subfamily.


ensembl_gene_id: BSU28000
symbol: minC
gene_biotype: protein_coding
description:
  Cell-division regulator (septum placement); Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization. The MinCD complex plays an important role in asymmetric septum formation during sporulation of B.subtilis cells.


ensembl_gene_id: BSU28010
symbol: mreD
gene_biotype: protein_coding
description:
  Cell-shape determining protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins (By similarity).


ensembl_gene_id: BSU28020
symbol: mreC
gene_biotype: protein_coding
description:
  Cell-shape determining protein; Involved in formation and maintenance of cell shape. Required for the formation of proper helical filaments of MreB and for cell wall synthesis in the cylindrical part of the cell leading to cell elongation; Belongs to the MreC family.


ensembl_gene_id: BSU28030
symbol: mreB
gene_biotype: protein_coding
description:
  Cell-shape determining protein; Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature (By similarity). Filaments rotate around the cell circumference in concert with the cell wall synthesis enzymes. The process is driven by the cell wall synthesis machinery and does not depend on MreB polymerization. The [...]


ensembl_gene_id: BSU28040
symbol: radC
gene_biotype: protein_coding
description:
  Putative DNA repair protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU28050
symbol: maf
gene_biotype: protein_coding
description:
  Septum formation DNA-binding protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. Can also hydrolyze CTP and the modified nucleotides pseudo- UTP, 5-methyl-CTP (m(5)CTP) and 5-methyl-UTP (m(5)UTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: BSU28070
symbol: comC
gene_biotype: protein_coding
description:
  Membrane protease and transmethylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue; Belongs to the peptidase A24 family.


ensembl_gene_id: BSU28080
symbol: folC
gene_biotype: protein_coding
description:
  Folyl-polyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate, leading to folylpolyglutamate derivatives.


ensembl_gene_id: BSU28090
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity). Catalyzes the attachment of valine to tRNA(Val); Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: BSU28100
symbol: ysxE
gene_biotype: protein_coding
description:
  Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.


ensembl_gene_id: BSU28110
symbol: spoVID
gene_biotype: protein_coding
description:
  Morphogenetic spore protein (stage VI sporulation); Required for assembly of a normal spore coat. May be a component of the innermost layer of the spore coat that aids in its adherence to the prespore.


ensembl_gene_id: BSU28120
symbol: hemL
gene_biotype: protein_coding
description:
  Glutamate-1-semialdehyde 2,1-aminotransferase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU28130
symbol: hemB
gene_biotype: protein_coding
description:
  Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).


ensembl_gene_id: BSU28140
symbol: hemD
gene_biotype: protein_coding
description:
  Uroporphyrinogen III cosynthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. Belongs to the uroporphyrinogen-III synthase family.


ensembl_gene_id: BSU28150
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: BSU28160
symbol: hemX
gene_biotype: protein_coding
description:
  Negative effector of the concentration of glutamyl-tRNA reductase HemA; Required for HemL synthesis; To M.leprae U1620K.


ensembl_gene_id: BSU28170
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: BSU28190
symbol: ysxC
gene_biotype: protein_coding
description:
  GTPase involved in ribosome 50S subunit assembly; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: BSU28200
symbol: lonA
gene_biotype: protein_coding
description:
  Class III heat-shock ATP-dependent LonA protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity). Has been implicated in preventing sigma(G) activity under non-sporulation conditions.


ensembl_gene_id: BSU28210
symbol: lonB
gene_biotype: protein_coding
description:
  LonB ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity); Belongs to the peptidase S16 family.


ensembl_gene_id: BSU28220
symbol: clpX
gene_biotype: protein_coding
description:
  Protein unfolding ATPase required for presentation of proteins to proteases; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Probably the major protease that degrades proteins tagged by trans-translation.


ensembl_gene_id: BSU28230
symbol: tig
gene_biotype: protein_coding
description:
  Prolyl isomerase (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity). Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: BSU28250
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase (small subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: BSU28260
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase (large subunit); Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate; Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.


ensembl_gene_id: BSU28270
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.


ensembl_gene_id: BSU28280
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: BSU28290
symbol: ilvC
gene_biotype: protein_coding
description:
  Acetohydroxy-acid isomeroreductase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: BSU28300
symbol: ilvH
gene_biotype: protein_coding
description:
  Acetolactate synthase (acetohydroxy-acid synthase) (small subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the acetolactate synthase small subunit family.


ensembl_gene_id: BSU28310
symbol: ilvB
gene_biotype: protein_coding
description:
  Acetolactate synthase (acetohydroxy-acid synthase) (large subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU28330
symbol: ysnE
gene_biotype: protein_coding
description:
  Putative indole acetic acid acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family.


ensembl_gene_id: BSU28340
symbol: ysnF
gene_biotype: protein_coding
description:
  Putative stress response protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; phenotype.


ensembl_gene_id: BSU28350
symbol: ysnB
gene_biotype: protein_coding
description:
  Phosphoesterase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; Belongs to the metallophosphoesterase superfamily. YfcE family.


ensembl_gene_id: BSU28360
symbol: rdgB
gene_biotype: protein_coding
description:
  Inosine/xanthosine triphosphate pyrophosphatase (subunit A); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: BSU28370
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. Plays a role in the secondary pathway of 23S rRNA 3' end maturation.


ensembl_gene_id: BSU28380
symbol: gerM
gene_biotype: protein_coding
description:
  Germination (cortex hydrolysis) and sporulation (stage II, multiple polar septa) lytic enzyme; Unknown. Affects both sporulation and germination.


ensembl_gene_id: BSU28410
symbol: gerE
gene_biotype: protein_coding
description:
  Transcriptional regulator; Involved in the regulation of spore formation. Directs the transcription of several genes that encode structural components of the protein coat that encases the mature spore (CotB, CotC, CotG, CotS, CotV, CotW, CotX, CotY and CotZ). Controls also the cgeAB and cgeCDE operons.


ensembl_gene_id: BSU28430
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase (iron-sulfur protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: BSU28440
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase (flavoprotein subunit); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.


ensembl_gene_id: BSU28450
symbol: sdhC
gene_biotype: protein_coding
description:
  Succinate dehydrogenase (cytochrome b558 subunit); Di-heme cytochrome of the succinate dehydrogenase complex.


ensembl_gene_id: BSU28470
symbol: lysC
gene_biotype: protein_coding
description:
  Aspartokinase II alpha subunit (aa 1->408) and beta subunit (aa 246->408); Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.


ensembl_gene_id: BSU28490
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC (subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: BSU28500
symbol: trxA
gene_biotype: protein_coding
description:
  Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.


ensembl_gene_id: BSU28510
symbol: xsa
gene_biotype: protein_coding
description:
  alpha-L-arabinofuranosidase; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-L-arabinofuranosyl residues in different hemicellulosic homopolysaccharides (branched and debranched arabinans) and heteropolysaccharides (arabinoxylans). It is able to hydrolyze the alpha-(1->5)-glycosidic linkages of linear alpha-(1->5)-L-arabinan (debranched), sugar beet arabinan (branched) and wheat arabinoxylan. Moreover, it displays higher activity towards branched arabinan, a molecule comprising a ba [...]


ensembl_gene_id: BSU28520
symbol: etfA
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein (alpha subunit); The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).


ensembl_gene_id: BSU28530
symbol: etfB
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein (beta subunit); The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).


ensembl_gene_id: BSU28550
symbol: fadR
gene_biotype: protein_coding
description:
  Transcriptional regulator of fatty acids degradation (TetR/AcrR family); Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifically inhibited by long chain fatty acyl-CoA compounds of 14-20 carbon atoms in length.


ensembl_gene_id: BSU28560
symbol: lcfA
gene_biotype: protein_coding
description:
  Long chain acyl-CoA ligase (degradative); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU28580
symbol: mutSB
gene_biotype: protein_coding
description:
  Putative DNA mismatch repair enzyme; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.


ensembl_gene_id: BSU28590
symbol: polX
gene_biotype: protein_coding
description:
  DNA polymerase/3'-5' exonuclease X; Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a single-nucleotide gap, allowing further sealing of the resulting nick by a DNA ligase, points to a putative role in base excision repair (BER) during the B.subtilis life cycle. Moreover, also possesses a 3'-5' exonuclease activity able to edit unpaired 3'-termini in a gapped DNA substrate and likely invo [...]


ensembl_gene_id: BSU28610
symbol: yshA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity); Belongs to the ZapA family. Type 2 subfamily.


ensembl_gene_id: BSU28620
symbol: rnhC
gene_biotype: protein_coding
description:
  Ribonuclease HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. RnhC subfamily.


ensembl_gene_id: BSU28630
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase (beta subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: BSU28640
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase (alpha subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: BSU28650
symbol: ysgA
gene_biotype: protein_coding
description:
  Putative RNA methylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: BSU28660
symbol: sspI
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the SspI family.


ensembl_gene_id: BSU28670
symbol: ysfB
gene_biotype: protein_coding
description:
  Putative regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs to the CdaR family.


ensembl_gene_id: BSU28680
symbol: glcD
gene_biotype: protein_coding
description:
  Glycolate oxidase subunit; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is also able to oxidize D-lactate ((R)- lactate). Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown. Belongs to the FAD-binding oxidoreductase/transferase type 4 family.


ensembl_gene_id: BSU28690
symbol: glcF
gene_biotype: protein_coding
description:
  Glycolate oxidase iron-sulfur subunit; Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is also able to oxidize D-lactate ((R)- lactate). Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown.


ensembl_gene_id: BSU28710
symbol: cstA
gene_biotype: protein_coding
description:
  Carbon starvation-induced membrane protein; Involved in peptide utilization. Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.


ensembl_gene_id: BSU28720
symbol: abfA
gene_biotype: protein_coding
description:
  alpha-L-arabinofuranosidase; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the cleavage of terminal alpha-(1->5)-arabinofuranosyl bonds in different hemicellulosic homopolysaccharides (branched and debranched arabinans). It acts preferentially on arabinotriose, arabinobiose and linear alpha- (1->5)-L-arabinan, and is much less effective on branched sugar beet arabinan; Belongs to the glycosyl hydrolase 51 family.


ensembl_gene_id: BSU28730
symbol: araQ
gene_biotype: protein_coding
description:
  Arabinose/arabinan permease; Part of the binding-protein-dependent transport system for L- arabinose. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU28760
symbol: araM
gene_biotype: protein_coding
description:
  Glycerol-1-phosphate dehydrogenase [NAD(P)+]; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species. Prefers NADH over NADPH as coenzyme. Is also able to catalyze the reverse reaction, i.e. the NAD(+)-dependent oxidation of G1P but not of G3P. Does not possess glycerol dehydrogenase activity.


ensembl_gene_id: BSU28770
symbol: araL
gene_biotype: protein_coding
description:
  Glycolytic and pentose phosphate intermediates phosphatase; Catalyzes the dephosphorylation of C5 and C6 carbon sugars in vitro. Catalyzes the dephosphorylation of 3'-AMP and phosphoserine in vitro.


ensembl_gene_id: BSU28780
symbol: araD
gene_biotype: protein_coding
description:
  L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).


ensembl_gene_id: BSU28790
symbol: araB
gene_biotype: protein_coding
description:
  L-ribulokinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the ribulokinase family.


ensembl_gene_id: BSU28810
symbol: abnA
gene_biotype: protein_coding
description:
  Arabinan-endo 1,5-alpha-L-arabinase; Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall. Catalyzes the internal cleavage of alpha-(1->5)-L-arabinofuranosyl residues of linear 1,5-alpha-L-arabinan and of branched sugar beet arabinan. It displays no activity against heavily substituted arabinans or a range of other polysaccharides (larch wood arabinogalactan, wheat arabinoxylan and p- nitrophenyl-alpha-L-arabinofuranoside). The enzyme activity is progressively reduced as alpha-(1->5)-chains become shorter or more highly substitu [...]


ensembl_gene_id: BSU28830
symbol: ysdB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; May mediate a negative feedback loop that down-regulates the expression of the sigma-W regulon following the activation of sigma-W in response to conditions of cell envelope stress. Might interact with and inhibit the activity of the protease PrsW, or could bind to the anti-sigma-W factor RsiW and thereby protect it from PrsW-mediated cleavage.


ensembl_gene_id: BSU28840
symbol: ysdA
gene_biotype: protein_coding
description:
  Putative membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU28850
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity).


ensembl_gene_id: BSU28860
symbol: rpmI
gene_biotype: protein_coding
description:
  Ribosomal protein L35; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; structure.


ensembl_gene_id: BSU28870
symbol: infC
gene_biotype: protein_coding
description:
  Initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: BSU28900
symbol: lrgB
gene_biotype: protein_coding
description:
  Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.


ensembl_gene_id: BSU28910
symbol: lrgA
gene_biotype: protein_coding
description:
  Antiholin factor; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidA/LrgA family. LrgA subfamily.


ensembl_gene_id: BSU28920
symbol: lytT
gene_biotype: protein_coding
description:
  Two-component response regulator [LytS]; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.


ensembl_gene_id: BSU28930
symbol: lytS
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [LytT]; Member of the two-component regulatory system LytS/LytT that probably regulates genes involved in cell wall metabolism.


ensembl_gene_id: BSU28940
symbol: ysaA
gene_biotype: protein_coding
description:
  Putative phosphatase; Catalyzes the last step of the phosphorylated serine biosynthetic pathway, i.e. dephosphorylation of O-phospho-L-serine to form L-serine. To a lesser extent, is also able to dephosphorylate phosphothreonine, phosphoethanolamine, and histidinol phosphate in vitro; Belongs to the HAD-like hydrolase superfamily.


ensembl_gene_id: BSU28950
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr); Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: BSU28990
symbol: dnaB
gene_biotype: protein_coding
description:
  Helicase loading protein; Probable component of primosome involved in the initiation of DNA replication. It is essential for both replication initiation and membrane attachment of the origin region of the chromosome and plasmid pUB110.


ensembl_gene_id: BSU29000
symbol: nrdR
gene_biotype: protein_coding
description:
  Negative regulator of transcription of ribonucleotide reductase nrd genes and operons; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: BSU29010
symbol: speD
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.


ensembl_gene_id: BSU29020
symbol: gapB
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase; Involved in the gluconeogenesis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3- bisphosphoglycerate (BPG) using the cofactor NADP. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NADP to NADPH. The reduced NADPH is then exchanged with the second NADP, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the gl [...]


ensembl_gene_id: BSU29030
symbol: ytcD
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (MarD family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU29050
symbol: ytbE
gene_biotype: protein_coding
description:
  Putative aldo/keto reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the aldo/keto reductase family.


ensembl_gene_id: BSU29060
symbol: coaE
gene_biotype: protein_coding
description:
  Dephosphocoenzyme A kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: BSU29080
symbol: mutM
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosidase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions (By similarity). Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 8-oxo-dGTP. Has AP (apurinic/apyrimidi [...]


ensembl_gene_id: BSU29090
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.


ensembl_gene_id: BSU29100
symbol: phoR
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals.


ensembl_gene_id: BSU29110
symbol: phoP
gene_biotype: protein_coding
description:
  Two-component response regulator; Member of the two-component regulatory system PhoP/PhoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase.


ensembl_gene_id: BSU29130
symbol: icd
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU29140
symbol: citZ
gene_biotype: protein_coding
description:
  Citrate synthase II; Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect; Belongs to the citrate synthase family.


ensembl_gene_id: BSU29180
symbol: pyk
gene_biotype: protein_coding
description:
  Pyruvate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; In the C-terminal section; belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: BSU29190
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub- subfamily.


ensembl_gene_id: BSU29200
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase (carboxyltransferase alpha subunit); Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. Belongs to the AccA family.


ensembl_gene_id: BSU29210
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase (carboxyltransferase beta subunit); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: BSU29220
symbol: ytsJ
gene_biotype: protein_coding
description:
  NADP-dependent malic enzyme (conversion of malate into pyruvate); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU29230
symbol: dnaE
gene_biotype: protein_coding
description:
  DNA polymerase III (alpha subunit); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity); Belongs to the DNA polymerase type-C family. DnaE subfamily.


ensembl_gene_id: BSU29239
symbol: ytrH
gene_biotype: protein_coding
description:
  Membrane protein involved in a sporulation process; Involved in sporulation. May contribute to cortex formation or stability.


ensembl_gene_id: BSU29250
symbol: nrnA
gene_biotype: protein_coding
description:
  Oligoribonuclease (nanoRNAse), 3',5'-bisphosphate nucleotidase; Bifunctional enzyme which has both oligoribonuclease and pAp- phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 3-mers. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction , and 11-mers in a 5' to 3' direction. Converts 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.


ensembl_gene_id: BSU29290
symbol: ytnL
gene_biotype: protein_coding
description:
  Putative aminohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase M20 family.


ensembl_gene_id: BSU29300
symbol: rbfK
gene_biotype: protein_coding
description:
  RNA-binding cryptic riboflavin kinase regulatory protein; May be directly involved in the regulation of the rib genes. C-terminal part of RibR specifically binds to RFN of the rib leader of the riboflavin biosynthetic operon. The RFN element is a sequence within the rib-leader mRNA reported to serve as a receptor for an FMN- dependent riboswitch. Possibly, RibR produces the comodulator FMN through its own N-terminal flavokinase activity. FMN-activated RibR may stabilize the anti-anti terminator structure of RFN mRNA, causing transcription termination of the rib genes in trans.


ensembl_gene_id: BSU29310
symbol: ytnJ
gene_biotype: protein_coding
description:
  Putative monooxygenase; May play a role in methionine degradation. May play a role in a sulfur salvage pathway.


ensembl_gene_id: BSU29320
symbol: ytnI
gene_biotype: protein_coding
description:
  Putative redoxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glutaredoxin family.


ensembl_gene_id: BSU29330
symbol: ytmO
gene_biotype: protein_coding
description:
  Putative monooxygenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To bacterial alkanal monooxygenase alpha and beta chains.


ensembl_gene_id: BSU29340
symbol: tcyN
gene_biotype: protein_coding
description:
  Sulfur-containing amino-acid ABC transporter (ATP-binding protein); Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Responsible for energy coupling to the transport system (Probable). Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the ABC transporter superfamily. L-cystine importer (TC 3.A.1.3.13) family.


ensembl_gene_id: BSU29350
symbol: tcyM
gene_biotype: protein_coding
description:
  Sulfur-containing amino acid ABC transporter (permease); Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Is also involved in cystathionine, djenkolate, and S-methylcysteine transport.


ensembl_gene_id: BSU29370
symbol: tcyK
gene_biotype: protein_coding
description:
  Sulfur-containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: BSU29380
symbol: tcyJ
gene_biotype: protein_coding
description:
  Sulfur containing amino acid ABC transporter binding lipoprotein; Part of the ABC transporter complex TcyJKLMN involved in L- cystine import. Is also involved in cystathionine, djenkolate, and S- methylcysteine transport; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: BSU29400
symbol: ytlI
gene_biotype: protein_coding
description:
  Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources.


ensembl_gene_id: BSU29420
symbol: ytkK
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-acyl-carrier protein reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU29430
symbol: ytzD
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 11423008.


ensembl_gene_id: BSU29440
symbol: argH
gene_biotype: protein_coding
description:
  Argininosuccinate lyase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU29450
symbol: argG
gene_biotype: protein_coding
description:
  Argininosuccinate synthase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: BSU29460
symbol: moaB
gene_biotype: protein_coding
description:
  Molybdopterin GTP-binding precursor Z biosynthesis component; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: BSU29470
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction. Appears to favor the formation of acetate. Involved in the secretion of excess carbohydrate.


ensembl_gene_id: BSU29480
symbol: ytxK
gene_biotype: protein_coding
description:
  Putative nucleic acid methyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To type I restriction system adenine methylases.


ensembl_gene_id: BSU29490
symbol: tpx
gene_biotype: protein_coding
description:
  Putative peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.


ensembl_gene_id: BSU29530
symbol: sppA
gene_biotype: protein_coding
description:
  Signal peptide peptidase; Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides. Belongs to the peptidase S49 family.


ensembl_gene_id: BSU29540
symbol: ppnKB
gene_biotype: protein_coding
description:
  Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: BSU29550
symbol: ytcJ
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the metallo-dependent hydrolases superfamily.


ensembl_gene_id: BSU29560
symbol: ytcI
gene_biotype: protein_coding
description:
  Putative acyl-coenzyme A synthetase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: BSU29570
symbol: sspA
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein (alpha-type SASP); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.


ensembl_gene_id: BSU29580
symbol: thiI
gene_biotype: protein_coding
description:
  Putative persulfide ATP pyrophosphatase involved in thiamine biosynthesis and tRNA modification; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: BSU29600
symbol: braB
gene_biotype: protein_coding
description:
  Branched-chain amino acid-Na+ symporter; Component of the transport system for branched-chain amino acids (leucine, isoleucine and valine) Which is coupled to a proton motive force.


ensembl_gene_id: BSU29610
symbol: ezrA
gene_biotype: protein_coding
description:
  Negative regulator of FtsZ ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization.


ensembl_gene_id: BSU29620
symbol: hisJ
gene_biotype: protein_coding
description:
  Histidinol phosphate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the PHP hydrolase family. HisK subfamily.


ensembl_gene_id: BSU29630
symbol: refZ
gene_biotype: protein_coding
description:
  Regulator of FtsZ; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU29640
symbol: ytsP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the free Met sulfoxide reductase family.


ensembl_gene_id: BSU29650
symbol: ytrP
gene_biotype: protein_coding
description:
  Putative diguanylate cyclase-related enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU29660
symbol: rpsD
gene_biotype: protein_coding
description:
  Ribosomal protein S4 (BS4); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.  S4 represses its own expression; it is not know if this is at the level of translation or of mRNA stability; Belongs to the universal ribosomal protein uS4 family.


ensembl_gene_id: BSU29670
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).


ensembl_gene_id: BSU29680
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity). Has a role in growth and sporulation on acetate.


ensembl_gene_id: BSU29690
symbol: acuA
gene_biotype: protein_coding
description:
  Protein acetyltransferase; Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue.


ensembl_gene_id: BSU29700
symbol: acuB
gene_biotype: protein_coding
description:
  Component of the acetoin degradation regulation pathway; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source.


ensembl_gene_id: BSU29710
symbol: acuC
gene_biotype: protein_coding
description:
  Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family.


ensembl_gene_id: BSU29720
symbol: ytxE
gene_biotype: protein_coding
description:
  Putative flagellar motor apparatus component; May be involved in some transport function; Belongs to the MotB family.


ensembl_gene_id: BSU29730
symbol: ytxD
gene_biotype: protein_coding
description:
  Putative flagellar motor component; May be involved in some transport function; Belongs to the MotA family.


ensembl_gene_id: BSU29740
symbol: ccpA
gene_biotype: protein_coding
description:
  Transcriptional regulator (Lacl family); Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions. Interacts with either P- Ser-HPr or P-Ser-Crh, leading to the formation of a complex that binds to DNA at the catabolite-response elements (cre). Binding to DNA allows activation or repression of many different genes and operons.


ensembl_gene_id: BSU29750
symbol: aroX
gene_biotype: protein_coding
description:
  3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I DAHP synthase family.


ensembl_gene_id: BSU29760
symbol: ytxJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232.


ensembl_gene_id: BSU29770
symbol: ytxH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16291680, 8733232; To C.plantagineum desiccation-related protein clone PCC3- 06.


ensembl_gene_id: BSU29805
symbol: sftA
gene_biotype: protein_coding
description:
  DNA translocase; Required for the accurate completion of chromosome partitioning, in part by promoting efficient resolution of chromosome dimers, before the formation of the division septum. Binds to DNA in a non-specific manner. Shows ATPase activity. Not required for cytokinesis.


ensembl_gene_id: BSU29820
symbol: ytpR
gene_biotype: protein_coding
description:
  Putative tRNA binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU29830
symbol: ytpQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12719520, 21949854; Belongs to the UPF0354 family.


ensembl_gene_id: BSU29840
symbol: ytpP
gene_biotype: protein_coding
description:
  Putative thiol-disulfide oxidoreductase with thioredoxin domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU29850
symbol: ytoQ
gene_biotype: protein_coding
description:
  Putative enzyme with sugar binding fold; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU29860
symbol: ytoP
gene_biotype: protein_coding
description:
  Glutamyl aminopeptidase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU29890
symbol: ytnP
gene_biotype: protein_coding
description:
  Putative metal-dependent hydrolase; Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S.griseus. Thus, serves as a defensive strategy against competing bacteria. The putative target for YtnP may be a gamma-butyrolactone termed A factor, which is the quorum-sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S.griseus.


ensembl_gene_id: BSU29900
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.


ensembl_gene_id: BSU29920
symbol: ytmP
gene_biotype: protein_coding
description:
  Putative kinase/phosphotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the aminoglycoside phosphotransferase family.


ensembl_gene_id: BSU29930
symbol: amyX
gene_biotype: protein_coding
description:
  Pullulanase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BSU29940
symbol: ytlR
gene_biotype: protein_coding
description:
  Putative phospholipid kinase; May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro.


ensembl_gene_id: BSU29960
symbol: ytlP
gene_biotype: protein_coding
description:
  2'-5' RNA-ligase family protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: BSU29970
symbol: ytkP
gene_biotype: protein_coding
description:
  Putative cysteine synthase-like protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU29980
symbol: ytjP
gene_biotype: protein_coding
description:
  Putative dipeptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU29990
symbol: pbuO
gene_biotype: protein_coding
description:
  Hypoxanthine/guanine permease; Involved in the uptake of the purine bases hypoxanthine and guanine. May work at purine concentrations higher than 100 uM.


ensembl_gene_id: BSU30020
symbol: ytzE
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (DeoR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU30035
symbol: ytzG
gene_biotype: protein_coding
description:
  Putative 16S pseudouridylate synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU30050
symbol: ytgP
gene_biotype: protein_coding
description:
  Putative enzyme involved in polysaccharide biosynthesis; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. Not essential for growth.


ensembl_gene_id: BSU30060
symbol: ytfP
gene_biotype: protein_coding
description:
  Putative NAD(FAD) dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU30070
symbol: opuD
gene_biotype: protein_coding
description:
  Glycine betaine transporter; High-affinity uptake of glycine betaine. Does not mediate either carnitine or choline uptake; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: BSU30080
symbol: yteV
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8990290.


ensembl_gene_id: BSU30090
symbol: yteU
gene_biotype: protein_coding
description:
  Putative membrane enzyme for rhamnogalaturonan degradation; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU30100
symbol: yteT
gene_biotype: protein_coding
description:
  Putative dehydrogenase of rhamnogalaturonan degradation; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the Gfo/Idh/MocA family.


ensembl_gene_id: BSU30110
symbol: yteS
gene_biotype: protein_coding
description:
  Putative lipoprotein required for rhamnogalaturonan degradation; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls.


ensembl_gene_id: BSU30120
symbol: yteR
gene_biotype: protein_coding
description:
  Unsaturated rhamnogalacturonyl hydrolase; Catalyzes the hydrolysis of unsaturated rhamnogalacturonan disaccharide to yield unsaturated D-galacturonic acid and L-rhamnose. It cannot act on unsaturated glucuronyl hydrolase (UGL) substrates containing unsaturated D-glucuronic acid at the non-reducing terminus, although the active pockets of YesR and UGL are very similar.


ensembl_gene_id: BSU30135
symbol: yteP
gene_biotype: protein_coding
description:
  Putative permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane. May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls.


ensembl_gene_id: BSU30150
symbol: ytdP
gene_biotype: protein_coding
description:
  Putative membrane bound transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU30160
symbol: ytcQ
gene_biotype: protein_coding
description:
  Putative ABC transporter (binding lipoprotein); Probably part of a binding-protein-dependent transport system; Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BSU30170
symbol: ytcP
gene_biotype: protein_coding
description:
  Putative ABC transporter (permease); Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BSU30180
symbol: ytbQ
gene_biotype: protein_coding
description:
  Putative nucleoside-diphosphate-sugar epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: BSU30190
symbol: bioI
gene_biotype: protein_coding
description:
  Cytochrome P450 for pimelic acid formation for biotin biosynthesis; Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for biotin biosynthesis. It has high affinity for long-chain fatty acids with the greatest affinity for myristic acid; Belongs to the cytochrome P450 family.


ensembl_gene_id: BSU30200
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: BSU30210
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: BSU30220
symbol: bioF
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: BSU30230
symbol: bioK
gene_biotype: protein_coding
description:
  Lysine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from L-lysine to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). B.subtilis is the only bacterium known to utilize L-lysine as an amino donor in the biosynthesis of DAPA. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: BSU30240
symbol: bioW
gene_biotype: protein_coding
description:
  6-carboxyhexanoate-CoA ligase (pimeloyl-CoA synthase); Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.


ensembl_gene_id: BSU30260
symbol: msmR
gene_biotype: protein_coding
description:
  Transcriptional regulator (LacI family); Represses the melibiose operon melREDCA in the absence of melibiose or raffinose. Binds to two binding sites at the promoter region of the operon.


ensembl_gene_id: BSU30270
symbol: msmE
gene_biotype: protein_coding
description:
  Multiple sugar-binding lipoprotein; Part of the ABC transporter complex MelEDC-MsmX involved in melibiose, raffinose and stachyose import. Binds melibiose, raffinose and stachyose.


ensembl_gene_id: BSU30280
symbol: amyD
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter (permease); Part of the ABC transporter complex MelEDC-MsmX involved in melibiose, raffinose and stachyose import. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU30290
symbol: amyC
gene_biotype: protein_coding
description:
  Maltose and multiple sugars ABC transporter (permease); Part of the ABC transporter complex MelEDC-MsmX involved in melibiose, raffinose and stachyose import. Probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU30300
symbol: melA
gene_biotype: protein_coding
description:
  alpha-D-galactoside galactohydrolase; Catalyzes the hydrolysis of melibiose and alpha-galactosides of the raffinose family of oligosaccharides (RFOs) such as raffinose and stachyose. Cannot act on polymeric substrates such as locust bean gum; Belongs to the glycosyl hydrolase 4 family.


ensembl_gene_id: BSU30320
symbol: leuS
gene_biotype: protein_coding
description:
  leucyl-tRNA synthetase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: BSU30330
symbol: ytvB
gene_biotype: protein_coding
description:
  Putative conserved membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.


ensembl_gene_id: BSU30340
symbol: ytvA
gene_biotype: protein_coding
description:
  Blue light GTP-binding receptor; Exhibits the same spectroscopical features and blue-light induced photochemistry as plants phototropins, with the reversible formation of a blue-shifted photoproduct, assigned to an FMN-cysteine thiol adduct. Although it is a positive regulator in the activation of the environmental signaling branch of the general stress transcription factor sigma-B, its precise role is undetermined.


ensembl_gene_id: BSU30360
symbol: yttA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818.


ensembl_gene_id: BSU30370
symbol: bceB
gene_biotype: protein_coding
description:
  ABC transporter (permease); Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export; Belongs to the ABC-4 integral membrane protein family.


ensembl_gene_id: BSU30380
symbol: bceA
gene_biotype: protein_coding
description:
  Bacitracin ABC efflux transporter (ATP-binding protein); Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export. Responsible for energy coupling to the transport system.


ensembl_gene_id: BSU30390
symbol: bceS
gene_biotype: protein_coding
description:
  Sensor protein BceS; Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin.


ensembl_gene_id: BSU30400
symbol: bceR
gene_biotype: protein_coding
description:
  Sensory transduction protein BceR; Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. When activated by BceS, binds to the upstream region of the bceAB promoter and up- regulates the expression of these two genes.


ensembl_gene_id: BSU30410
symbol: ytrF
gene_biotype: protein_coding
description:
  Metabolite permease; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.


ensembl_gene_id: BSU30420
symbol: ytrE
gene_biotype: protein_coding
description:
  ABC transporter (ATP-binding protein); Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.


ensembl_gene_id: BSU30430
symbol: ytrD
gene_biotype: protein_coding
description:
  ABC transporter, permease component; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.


ensembl_gene_id: BSU30460
symbol: ytrA
gene_biotype: protein_coding
description:
  Transcriptional regulator (GntR family); Negatively regulates ABC transporter complex ytrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.


ensembl_gene_id: BSU30480
symbol: ytqA
gene_biotype: protein_coding
description:
  Putative Fe-S oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU30490
symbol: ytqB
gene_biotype: protein_coding
description:
  Putative RNA methylase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily.


ensembl_gene_id: BSU30500
symbol: ytpB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the transformation of a linear C35 prenyl diphosphate chain to form tetraprenyl-beta-curcumene.


ensembl_gene_id: BSU30510
symbol: ytpA
gene_biotype: protein_coding
description:
  Phospholipase component of bacilysocin synthesis or export; Phospholipase involved in the biosynthesis of the antibiotic bacilysocin. It probably catalyzes the hydrolysis of the 2-sn-acyl moiety of phosphatidylglycerol to produce bacilysocin (lysophosphatidylglycerol). Is also able to catalyze the hydrolysis reaction of one acyl bond in phosphatidylcholine in vitro (actual cleavage point is unknown), resulting in lysophosphatidylcholine.


ensembl_gene_id: BSU30520
symbol: ytoA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: BSU30530
symbol: ytnA
gene_biotype: protein_coding
description:
  Putative amino acid permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU30550
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: BSU30560
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.


ensembl_gene_id: BSU30580
symbol: ytmA
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the peptidase S9B family.


ensembl_gene_id: BSU30595
symbol: ytlA
gene_biotype: protein_coding
description:
  Putative ABC transporter component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU30610
symbol: ytlC
gene_biotype: protein_coding
description:
  Putative ABC transporter component, ATP-binding; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU30620
symbol: ytlD
gene_biotype: protein_coding
description:
  Putative permease of ABC transporter; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity).


ensembl_gene_id: BSU30630
symbol: rppG
gene_biotype: protein_coding
description:
  Nucleoside and RNA triphosphate phosphohydrolase; Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo- dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A.T to G.C transversions (By similarity). Functions, in conjunction with MutT, to protect vegetatively growing cells from DNA- damaging agents such as H(2)O(2) or t-BHP (t-butylhydroperoxide). The 2 proteins do not however protect spores. According to phosphohydrola [...]


ensembl_gene_id: BSU30640
symbol: ytkC
gene_biotype: protein_coding
description:
  Putative autolytic amidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.


ensembl_gene_id: BSU30650
symbol: dps
gene_biotype: protein_coding
description:
  DNA-protecting protein, ferritin; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU30670
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD); Belongs to the LuxS family.


ensembl_gene_id: BSU30680
symbol: ytjA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: BSU30700
symbol: rpmEB
gene_biotype: protein_coding
description:
  Ribosomal protein L31; While neither of the L31 paralogs is essential, this protein does not seem to function as the main L31 protein. Has a higher affinity for 70S ribosomes than the zinc-containing L31 paralog; is able to displace it to varying extents, even under zinc-replete conditions.


ensembl_gene_id: BSU30710
symbol: ythA
gene_biotype: protein_coding
description:
  Putative cytochrome bd menaquinol oxidase subunit I; May have a role in sporulation. Can compensate for the loss of cytochrome aa3; Belongs to the cytochrome ubiquinol oxidase subunit 1 family.


ensembl_gene_id: BSU30720
symbol: ythB
gene_biotype: protein_coding
description:
  Putative cytochrome bd menaquinol oxidase subunit II; May have a role in sporulation. Can compensate for the loss of cytochrome aa3; Belongs to the cytochrome ubiquinol oxidase subunit 2 family.


ensembl_gene_id: BSU30740
symbol: mntD
gene_biotype: protein_coding
description:
  Manganese ABC transporter (permease); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for the translocation of the substrate across the membrane; Belongs to the ABC-3 integral membrane protein family.


ensembl_gene_id: BSU30760
symbol: mntB
gene_biotype: protein_coding
description:
  Manganese ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex MntABCD involved in manganese import. Probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU30770
symbol: mntA
gene_biotype: protein_coding
description:
  Manganese ABC transporter (manganese binding lipoprotein); Probably part of the ABC transporter complex MntABCD involved in manganese import.


ensembl_gene_id: BSU30780
symbol: menC
gene_biotype: protein_coding
description:
  O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: BSU30790
symbol: menE
gene_biotype: protein_coding
description:
  O-succinylbenzoic acid-CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.


ensembl_gene_id: BSU30800
symbol: menB
gene_biotype: protein_coding
description:
  Dihydroxynapthoic acid synthetase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: BSU30810
symbol: menH-2
gene_biotype: protein_coding
description:
  Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: BSU30820
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).


ensembl_gene_id: BSU30830
symbol: menF
gene_biotype: protein_coding
description:
  Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.


ensembl_gene_id: BSU30840
symbol: yteA
gene_biotype: protein_coding
description:
  Putative DksA homolog; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.


ensembl_gene_id: BSU30850
symbol: ytdA
gene_biotype: protein_coding
description:
  Putative UTP-glucose-1-phosphate uridylyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU30860
symbol: ytcA
gene_biotype: protein_coding
description:
  Putative UDP-glucose dehydrogenase; Catalyzes the conversion of UDP-glucose into UDP-glucuronate, one of the precursors of teichuronic acid.


ensembl_gene_id: BSU30870
symbol: ytcB
gene_biotype: protein_coding
description:
  Putative UDP-glucose epimerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: BSU30880
symbol: ytcC
gene_biotype: protein_coding
description:
  Putative glucosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.


ensembl_gene_id: BSU30890
symbol: ytxO
gene_biotype: protein_coding
description:
  Outer spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.


ensembl_gene_id: BSU30910
symbol: cotSA
gene_biotype: protein_coding
description:
  Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.


ensembl_gene_id: BSU30920
symbol: cotI
gene_biotype: protein_coding
description:
  Spore coat kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU30930
symbol: ytaB
gene_biotype: protein_coding
description:
  Putative receptor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc: putative receptor.


ensembl_gene_id: BSU30940
symbol: glgP
gene_biotype: protein_coding
description:
  Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: BSU30950
symbol: glgA
gene_biotype: protein_coding
description:
  Bacterial glycogen (starch) synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose; Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.


ensembl_gene_id: BSU30960
symbol: glgD
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase) beta subunit; Required for the synthesis of glycogen; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: BSU30970
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase (ADP-glucose pyrophosphorylase) subunit alpha; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.


ensembl_gene_id: BSU30980
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.


ensembl_gene_id: BSU30990
symbol: thiT
gene_biotype: protein_coding
description:
  Thiamin permease; Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins (By similarity); Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Thiamine transporter subfamily.


ensembl_gene_id: BSU31000
symbol: yuaI
gene_biotype: protein_coding
description:
  Putative acetyl-transferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family.


ensembl_gene_id: BSU31010
symbol: yuaG
gene_biotype: protein_coding
description:
  Putative flotillin-like protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU31020
symbol: yuaF
gene_biotype: protein_coding
description:
  Putative membrane integrity integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU31040
symbol: yuaD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11886751.


ensembl_gene_id: BSU31050
symbol: gbsB
gene_biotype: protein_coding
description:
  Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine from choline; Belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: BSU31060
symbol: gbsA
gene_biotype: protein_coding
description:
  Glycine betaine aldehyde dehydrogenase, NAD+-dependent; Involved in the biosynthesis of the osmoprotectant glycine betaine from choline. Catalyzes the oxidation of betaine aldehyde to betaine. Shows specificity for betaine aldehyde as substrate. Can use both NAD(+) and NADP(+), but NAD(+) is strongly preferred.


ensembl_gene_id: BSU31070
symbol: yuaC
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved; Belongs to the GbsR family.


ensembl_gene_id: BSU31080
symbol: bslA
gene_biotype: protein_coding
description:
  Biofilm hydrophobic layer component; Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix.


ensembl_gene_id: BSU31090
symbol: ktrA
gene_biotype: protein_coding
description:
  Potassium uptake protein; Catalytic subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress.


ensembl_gene_id: BSU31100
symbol: ktrB
gene_biotype: protein_coding
description:
  Potassium transporter ATPase; Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress.


ensembl_gene_id: BSU31120
symbol: lytG
gene_biotype: protein_coding
description:
  Exoglucosaminidase; Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Catalyzes the hydrolysis of 1,4-beta-linkages between N-acetyl-D-glucosamine and N- acetylmuramic acid residues in peptidoglycan. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division.


ensembl_gene_id: BSU31140
symbol: cdoA
gene_biotype: protein_coding
description:
  Cysteine dioxygenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU31150
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: BSU31170
symbol: yulF
gene_biotype: protein_coding
description:
  Enzyme involved in biofilm formation; Catalyzes the NADPH-dependent reduction of scyllo-inosose (SIS) to scyllo-inositol (SI) in vitro, but is unable to dehydrogenate scyllo-inositol and myo-inositol. Is less efficient than the functional paralog IolW. Under physiological conditions, may primarily function as an NADPH-dependent oxidoreductase that reduces carbonyl group(s) in its substrates. Cannot use NADH instead of NADPH.


ensembl_gene_id: BSU31180
symbol: rhaA
gene_biotype: protein_coding
description:
  L-rhamnose isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the rhamnose isomerase family.


ensembl_gene_id: BSU31200
symbol: rhaB
gene_biotype: protein_coding
description:
  Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family.


ensembl_gene_id: BSU31220
symbol: rhaD
gene_biotype: protein_coding
description:
  Putative Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU31270
symbol: tgl
gene_biotype: protein_coding
description:
  Protein-glutamine gamma-glutamyltransferase (transglutaminase); Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links. In wild-type spores at 37 degrees Celsius, tgl mediates the cross-linking of GerQ in higher molecular mass forms, probably in cooperation with YabG; Belongs to the bacillus TGase family.


ensembl_gene_id: BSU31280
symbol: yugU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0047 family.


ensembl_gene_id: BSU31290
symbol: yugT
gene_biotype: protein_coding
description:
  Putative oligo-1,6-glucosidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BSU31300
symbol: yugS
gene_biotype: protein_coding
description:
  Putative membrane protein involved in divalent ion export; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU31310
symbol: yugP
gene_biotype: protein_coding
description:
  Putative metal-dependent protease/peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU31319
symbol: yuzI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Product type f: factor.


ensembl_gene_id: BSU31321
symbol: mstX
gene_biotype: protein_coding
description:
  Atypical membrane-integrating protein (Mistic protein); Chaperone that facilitates the production and integration of integral membrane proteins into the bacterial lipid bilayer.


ensembl_gene_id: BSU31322
symbol: yugO
gene_biotype: protein_coding
description:
  Putative potassium channel protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: BSU31350
symbol: pgi
gene_biotype: protein_coding
description:
  Glucose-6-phosphate isomerase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the GPI family.


ensembl_gene_id: BSU31360
symbol: yugK
gene_biotype: protein_coding
description:
  Putative NADH-dependent butanol dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU31390
symbol: yugI
gene_biotype: protein_coding
description:
  Putative RNA degradation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU31400
symbol: yugH
gene_biotype: protein_coding
description:
  Putative aspartate aminotransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU31420
symbol: yugF
gene_biotype: protein_coding
description:
  Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the DmpD/TodF/XylF esterase family.


ensembl_gene_id: BSU31440
symbol: patB
gene_biotype: protein_coding
description:
  Promiscuous cystathionine beta-lyase / cysteine desulfhydrase; Catalyzes the transformation of cystathionine to homocysteine. Also exhibits cysteine desulfhydrase activity in vitro, producing sulfide from cysteine; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily.


ensembl_gene_id: BSU31450
symbol: kinB
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the KinB activity.


ensembl_gene_id: BSU31460
symbol: kapB
gene_biotype: protein_coding
description:
  Factor required for KinB signal transduction and activation of the phosphorelay to sporulation; May play a role in the activation or the expression of KinB.


ensembl_gene_id: BSU31490
symbol: pbpD
gene_biotype: protein_coding
description:
  Penicillin-binding protein 4; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; In the C-terminal section; belongs to the transpeptidase family.


ensembl_gene_id: BSU31500
symbol: yuxK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the DCC thiol-disulfide oxidoreductase family.


ensembl_gene_id: BSU31520
symbol: yufL
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YufM]; Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA, maeN and yflS in presence of malate. Probably activates MalR by phosphorylation.


ensembl_gene_id: BSU31530
symbol: yufM
gene_biotype: protein_coding
description:
  Two-component response regulator [YufL]; Member of a two-component regulatory system MalK/MalR. Activates transcription of maeA, maeN and yflS in presence of malate by binding to their promoter region.


ensembl_gene_id: BSU31540
symbol: nupN
gene_biotype: protein_coding
description:
  Lipoprotein involved in guanosine transport; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.


ensembl_gene_id: BSU31550
symbol: nupO
gene_biotype: protein_coding
description:
  Guanosine ABC transporter (ATP-binding protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU31560
symbol: nupP
gene_biotype: protein_coding
description:
  Permease of ABC guanosine transporter; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.


ensembl_gene_id: BSU31570
symbol: nupQ
gene_biotype: protein_coding
description:
  Permease of ABC guanosine transporter; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity).


ensembl_gene_id: BSU31580
symbol: maeN
gene_biotype: protein_coding
description:
  Na+/malate symporter; Acts as a Na(+)-malate symporter, as it catalyzes malate- dependent uptake of Na(+) and Na(+)-dependent uptake of malate.


ensembl_gene_id: BSU31600
symbol: mrpA
gene_biotype: protein_coding
description:
  Sodium transporter component of a Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+). Belongs  [...]


ensembl_gene_id: BSU31610
symbol: mrpB
gene_biotype: protein_coding
description:
  Na+/H+ antiporter complex; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+). Belongs to the CPA3 antiporters (T [...]


ensembl_gene_id: BSU31620
symbol: mrpC
gene_biotype: protein_coding
description:
  Component of Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+). Belongs to the CPA3 antiporte [...]


ensembl_gene_id: BSU31630
symbol: mrpD
gene_biotype: protein_coding
description:
  Proton transporter component of Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+). Belongs to [...]


ensembl_gene_id: BSU31640
symbol: mrpE
gene_biotype: protein_coding
description:
  Non essential component of Na+/H+ antiporter; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+). Belongs to the  [...]


ensembl_gene_id: BSU31650
symbol: mrpF
gene_biotype: protein_coding
description:
  Efflux transporter for Na+ and cholate; Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual Na(+)/H(+) antiporter, although the six other Mrp proteins are all required for Na(+)/H(+) antiport activity and Na(+) resistance. MrpA is required for initiation of sporulation when external Na(+) concentration increases. Also transports Li(+) but not K(+), Ca(2+) or Mg(2+).


ensembl_gene_id: BSU31660
symbol: mrpG
gene_biotype: protein_coding
description:
  Non essential component of Na+/H+ antiporter; May enhance MrpA stability, assembly, or function. May play chaperone or assembly roles for MrpA and perhaps for other mrp proteins.


ensembl_gene_id: BSU31680
symbol: comA
gene_biotype: protein_coding
description:
  Two-component response regulator; Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes, including genes of the srfA operon, degQ, rapA, rapC, rapE, rapF, etc. Regulates indirectly, through the regulation of comK transcription, the expression of late competence genes.


ensembl_gene_id: BSU31690
symbol: comP
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation, at least partly interchangeable with that of SpoIIJ. Probably activates ComA by phosphorylation.


ensembl_gene_id: BSU31700
symbol: comX
gene_biotype: protein_coding
description:
  Competence pheromone precursor (pheromone peptide aa 46->55, geranyl-modified); Part of a major quorum-sensing system that regulates the development of genetic competence. Acts through the activation of the two-component regulatory system ComP/ComA composed of a sensor histidine kinase, ComP, and a response regulator, ComA, that regulates directly the transcription of over 20 genes. Transport through the membrane may involve Spo0K. Under certain conditions plays a role in sporulation.


ensembl_gene_id: BSU31710
symbol: comQ
gene_biotype: protein_coding
description:
  Isoprenyl transferase (pre-ComX modification); Involved in the maturation of ComX, part of a major quorum- sensing system that regulates the development of genetic competence.


ensembl_gene_id: BSU31720
symbol: degQ
gene_biotype: protein_coding
description:
  Pleiotropic regulator; Stimulates the phosphotransfer from phospho-DegS to DegU. Affects protease and levansucrose production.


ensembl_gene_id: BSU31730
symbol: yuzC
gene_biotype: protein_coding
description:
  Inner spore coat protein; Evidence 2b: Function of strongly homologous gene; Product type cp: cell process.


ensembl_gene_id: BSU31740
symbol: yuxH
gene_biotype: protein_coding
description:
  Putative phosphodiesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU31750
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: BSU31760
symbol: pncA
gene_biotype: protein_coding
description:
  Nicotinamidase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the isochorismatase family.


ensembl_gene_id: BSU31790
symbol: yueG
gene_biotype: protein_coding
description:
  Putative spore germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the GerPA/GerPF family.


ensembl_gene_id: BSU31850
symbol: yueC
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).


ensembl_gene_id: BSU31860
symbol: yueB
gene_biotype: protein_coding
description:
  Bacteriophage SPP1 receptor; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Bacteriophage SPP1 receptor. Essential for the irreversible adsorption of the bacteriophage.


ensembl_gene_id: BSU31875
symbol: yukB
gene_biotype: protein_coding
description:
  Putative cell division protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).


ensembl_gene_id: BSU31890
symbol: yukC
gene_biotype: protein_coding
description:
  Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).


ensembl_gene_id: BSU31900
symbol: yukD
gene_biotype: protein_coding
description:
  Putative bacteriocin; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Belongs to the EsaB family.


ensembl_gene_id: BSU31910
symbol: yukE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783.


ensembl_gene_id: BSU31920
symbol: yukF
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Mediates ald expression in response to alanine availability and is important for normal sporulation in B.subtilis. Belongs to the CdaR family.


ensembl_gene_id: BSU31930
symbol: ald
gene_biotype: protein_coding
description:
  L-alanine dehydrogenase; Catalyzes the reversible oxidative deamination of L-alanine to pyruvate. This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation.


ensembl_gene_id: BSU31959
symbol: ybdZ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11112781.


ensembl_gene_id: BSU31960
symbol: dhbF
gene_biotype: protein_coding
description:
  Siderophore 2,3-dihydroxybenzoate-glycine-threonine trimeric ester bacillibactin synthetase; Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains.


ensembl_gene_id: BSU31970
symbol: dhbB
gene_biotype: protein_coding
description:
  Isochorismatase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.


ensembl_gene_id: BSU31980
symbol: dhbE
gene_biotype: protein_coding
description:
  2,3-dihydroxybenzoate-AMP ligase; Involved in the biosynthesis of the catecholic siderophore bacillibactin. Catalyzes the activation of the carboxylate group of 2,3-dihydroxy-benzoate (DHB), via ATP-dependent PPi exchange reactions, to the acyladenylate.


ensembl_gene_id: BSU31990
symbol: dhbC
gene_biotype: protein_coding
description:
  Isochorismate synthase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the isochorismate synthase family.


ensembl_gene_id: BSU32000
symbol: dhbA
gene_biotype: protein_coding
description:
  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU32010
symbol: besA
gene_biotype: protein_coding
description:
  Bacillibactin trilactone hydrolase; Catalyzes the hydrolysis of the trilactone cycle of ferri- bacillibactin (ferri-BB) complex, leading to the formation of bacillibactin monomers and to cytosolic iron release, thus making iron available for metabolic use. Can also hydrolyze bacillibactin (BB), however the catalytic efficiency for ferri-BB hydrolysis is much higher than for BB.


ensembl_gene_id: BSU32020
symbol: yuiH
gene_biotype: protein_coding
description:
  Putative enzymes similar to sulfite oxidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU32040
symbol: yuiF
gene_biotype: protein_coding
description:
  Amino acid transporter; Evidence 2b: Function of strongly homologous gene; Product type t: transporter.


ensembl_gene_id: BSU32050
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity).


ensembl_gene_id: BSU32100
symbol: yumB
gene_biotype: protein_coding
description:
  Putative NAD-disulfide oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU32110
symbol: yumC
gene_biotype: protein_coding
description:
  ferredoxin-NADP+ reductase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the ferredoxin--NADP reductase type 2 family.


ensembl_gene_id: BSU32130
symbol: guaC
gene_biotype: protein_coding
description:
  GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (Probable).


ensembl_gene_id: BSU32140
symbol: paiB
gene_biotype: protein_coding
description:
  Putative enzyme; Involved in the reduction of extracellular and cell- associated protease levels, as well as in the reduced levels of alpha- amylase, levansucrase, alkaline phosphatase and sporulation inhibition, when present in high copy number.


ensembl_gene_id: BSU32150
symbol: paiA
gene_biotype: protein_coding
description:
  Polyamine N-acetyltransferase; Involved in the protection against polyamine toxicity by regulating their concentration. Also could be involved in the negative control of sporulation as well as production of degradative enzymes such as alpha-amylase, levansucrase and alkaline phosphatase. Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It possesses N1-acetyltransferase activity toward polyamine substrates including spermidine, spermine, aminopropylcadaverine, norspermidine, homospermidine [...]


ensembl_gene_id: BSU32160
symbol: sufA
gene_biotype: protein_coding
description:
  Chaperone involved in Fe-S cluster assembly; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; factor.


ensembl_gene_id: BSU32170
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: BSU32180
symbol: yutK
gene_biotype: protein_coding
description:
  Putative Na+(H+)/nucleoside cotransporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU32190
symbol: yuzB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0349 family.


ensembl_gene_id: BSU32200
symbol: yutJ
gene_biotype: protein_coding
description:
  Putative NADH dehydrogenase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU32210
symbol: yuzD
gene_biotype: protein_coding
description:
  Putative sulfur oxido-reduction management enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU32220
symbol: yutI
gene_biotype: protein_coding
description:
  Putative iron-sulfur scaffold protein; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.


ensembl_gene_id: BSU32230
symbol: yuxL
gene_biotype: protein_coding
description:
  Putative acylaminoacyl-peptidase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S9C family.


ensembl_gene_id: BSU32240
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: BSU32250
symbol: thrC
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: BSU32260
symbol: hom
gene_biotype: protein_coding
description:
  Homoserine dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU32280
symbol: yutG
gene_biotype: protein_coding
description:
  Putative phosphatidylglycerophosphatase A; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; To B.subtilis YpjQ.


ensembl_gene_id: BSU32290
symbol: yutF
gene_biotype: protein_coding
description:
  Putative p-nitrophenyl phosphatase; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family.


ensembl_gene_id: BSU32300
symbol: yutE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0331 family.


ensembl_gene_id: BSU32310
symbol: yutD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12770717.


ensembl_gene_id: BSU32330
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase (lipoic acid synthetase); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family.


ensembl_gene_id: BSU32340
symbol: lytH
gene_biotype: protein_coding
description:
  Sporulation-specific L-Ala-D-Glu endopeptidase; L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation.


ensembl_gene_id: BSU32370
symbol: yunD
gene_biotype: protein_coding
description:
  Putative nuclease/nucleotidase/phosphoesterase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU32390
symbol: yunF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0759 family.


ensembl_gene_id: BSU32410
symbol: pucH
gene_biotype: protein_coding
description:
  Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring.


ensembl_gene_id: BSU32420
symbol: pucR
gene_biotype: protein_coding
description:
  Transcriptional regulator of the purine degradation operon; Activates the expression of pucFG, pucH, pucI, pucJKLM and guaD, while it represses pucABCDE and its own expression. Belongs to the CdaR family.


ensembl_gene_id: BSU32450
symbol: pucL
gene_biotype: protein_coding
description:
  Urate oxidase with peroxide reductase N-terminal domain; Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline (OHCU) to (S)-allantoin.


ensembl_gene_id: BSU32460
symbol: pucM
gene_biotype: protein_coding
description:
  5-hydroxyisourate hydrolase; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).


ensembl_gene_id: BSU32469
symbol: yuzJ
gene_biotype: protein_coding
description:
  Putative type I toxin; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.


ensembl_gene_id: BSU32480
symbol: pucD
gene_biotype: protein_coding
description:
  Xanthine dehydrogenase, substrate and molybdenum cofactor subunit; Oxidizes hypoxanthine and xanthine to uric acid. Belongs to the xanthine dehydrogenase family.


ensembl_gene_id: BSU32500
symbol: pucB
gene_biotype: protein_coding
description:
  Enzyme for molybdopterin cofactor synthesis required for xanthine dehydrogenase; Required for xanthine dehydrogenase activity. Could be involved in formation of the molybdenum cofactor required by xanthine dehydrogenase.


ensembl_gene_id: BSU32510
symbol: pucA
gene_biotype: protein_coding
description:
  Xanthine dehydrogenase molybdopterin recruitment factor; Oxidizes hypoxanthine and xanthine to uric acid. PucA subunit could exert a molybdenum cofactor recruiting function.


ensembl_gene_id: BSU32520
symbol: pucG
gene_biotype: protein_coding
description:
  Vitamin B6-dependent (S)-ureidoglycine glyoxylate aminotransferase; Catalyzes the transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (glyoxylate) to yield oxalurate and glycine. Glyoxylate is the preferred substrate, but other amino-group acceptors can be used. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: BSU32530
symbol: pucF
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; Involved in the anaerobic nitrogen utilization via the assimilation of allantoin. Catalyzes specifically the hydrolysis of allantoate to yield CO2, NH3 and S-ureidoglycine, which is unstable and readily undergoes a second deamination by S- ureidoglycine aminohydrolase AllE to yield S-ureidoglycolate and NH3 (By similarity).


ensembl_gene_id: BSU32540
symbol: bsn
gene_biotype: protein_coding
description:
  Extracellular ribonuclease; Mg(2+)-activated ribonuclease which hydrolyzes RNA apparently nonspecifically into oligonucleotides with 5'-terminal phosphate.


ensembl_gene_id: BSU32550
symbol: yurJ
gene_biotype: protein_coding
description:
  Putative multiple sugar ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU32560
symbol: frlR
gene_biotype: protein_coding
description:
  FrlR transcriptional regulator (GntR family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU32570
symbol: frlD
gene_biotype: protein_coding
description:
  Fructoselysine kinase; Catalyzes the phosphorylation of a range of fructosamines to fructosamine 6-phosphates; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: BSU32580
symbol: frlM
gene_biotype: protein_coding
description:
  Fructose-amino acid permease; Probably part of the binding-protein-dependent transport system YurMNO. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.


ensembl_gene_id: BSU32600
symbol: frlO
gene_biotype: protein_coding
description:
  Fructose amino acid-binding lipoprotein; Probably part of the binding-protein-dependent transport system YurMNO; Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BSU32610
symbol: frlB
gene_biotype: protein_coding
description:
  fructoselysine-6-P-deglycase; Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid.


ensembl_gene_id: BSU32620
symbol: yurQ
gene_biotype: protein_coding
description:
  Putative excinuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


ensembl_gene_id: BSU32640
symbol: sspG
gene_biotype: protein_coding
description:
  Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU32650
symbol: yurS
gene_biotype: protein_coding
description:
  Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 9852018.


ensembl_gene_id: BSU32660
symbol: yurT
gene_biotype: protein_coding
description:
  Putative methylglyoxalase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glyoxalase I family.


ensembl_gene_id: BSU32670
symbol: sufB
gene_biotype: protein_coding
description:
  FeS cluster formation protein; The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity). Belongs to the UPF0051 (ycf24) family.


ensembl_gene_id: BSU32680
symbol: sufU
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly scaffold protein; Its function is controversial. Has been generally assumed to be an iron-sulfur cluster assembly scaffold protein , but more recent evidence suggest it is a sulfurtransferase rather than a scaffold assembly protein. Has been shown to bind low levels of a labile, air- sensitive Fe-S cluster; this can be assembled under anaerobic conditions from FeCl(3) and Li(2)S. Has been shown to be able to transfer this Fe-S cluster to an acceptor protein. Stimulates the cysteine desulfurase activity of SufS, for which it acts as a second substrate. Alkyl [...]


ensembl_gene_id: BSU32690
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Enzyme able to deliver sulfur to partners involved in Fe-S cluster assembly. Catalyzes the removal of elemental sulfur atoms from L-cysteine to produce L-alanine. Activity is stimulated 40- to 100-fold by SufU, which acts as a second substrate for this enzyme following release of Ala, and generating SufU.S. A mixture of SufS, SufU, Fra and L-cysteine is able to reconstitute Fe-S clusters on apo-aconitase (citB), reconstituting aconitase activity.


ensembl_gene_id: BSU32700
symbol: sufD
gene_biotype: protein_coding
description:
  FeS assembly protein SufD; The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation (By similarity). Belongs to the UPF0051 (ycf24) family.


ensembl_gene_id: BSU32710
symbol: sufC
gene_biotype: protein_coding
description:
  Sulfur mobilizing ABC protein, ATPase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the ABC transporter superfamily. Ycf16 family.


ensembl_gene_id: BSU32730
symbol: metQ
gene_biotype: protein_coding
description:
  Methionine ABC transporter, substrate binding lipoprotein; Part of the ABC transporter complex MetNPQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable); Belongs to the NlpA lipoprotein family.


ensembl_gene_id: BSU32740
symbol: metP
gene_biotype: protein_coding
description:
  Methionine ABC transporter, permease component; Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BSU32750
symbol: metN
gene_biotype: protein_coding
description:
  Methionine ABC transporter (ATP-binding protein); Part of the ABC transporter complex MetNPQ involved in methionine import. Responsible for energy coupling to the transport system (Probable). It has also been shown to be involved in methionine sulfoxide transport. Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.


ensembl_gene_id: BSU32770
symbol: yusE
gene_biotype: protein_coding
description:
  Putative thiol-disulfide oxidoreductase with thioredoxin domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU32780
symbol: yusF
gene_biotype: protein_coding
description:
  Putative ribonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.


ensembl_gene_id: BSU32800
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: BSU32810
symbol: yusI
gene_biotype: protein_coding
description:
  Putative oxidoreductase with thioredoxin domain; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the ArsC family.


ensembl_gene_id: BSU32830
symbol: fadA
gene_biotype: protein_coding
description:
  acetyl-CoA C-acyltransferase; Involved in the degradation of long-chain fatty acids; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: BSU32840
symbol: fadN
gene_biotype: protein_coding
description:
  enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Involved in the degradation of long-chain fatty acids; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: BSU32849
symbol: yuzL
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250.


ensembl_gene_id: BSU32870
symbol: yusO
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.


ensembl_gene_id: BSU32880
symbol: yusP
gene_biotype: protein_coding
description:
  Putative multidrug-efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU32940
symbol: yusV
gene_biotype: protein_coding
description:
  iron(III)-siderophore transporter (ATP binding component); Provides the ATPase subunit for at least 2 ABC transporter complexes; YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable), and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity).


ensembl_gene_id: BSU32950
symbol: yusW
gene_biotype: protein_coding
description:
  Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.


ensembl_gene_id: BSU32980
symbol: yusZ
gene_biotype: protein_coding
description:
  Oligoendopeptidase; Evidence 7: Gene remnant; Product type e: enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: BSU32990
symbol: mrgA
gene_biotype: protein_coding
description:
  Metalloregulation DNA-binding stress protein; Forms highly stable, multimeric protein-DNA complexes which accumulate in stationary-phase cells and protect against oxidative killing; Belongs to the Dps family.


ensembl_gene_id: BSU33000
symbol: htrB
gene_biotype: protein_coding
description:
  HtrA-like serine protease; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family.


ensembl_gene_id: BSU33010
symbol: cssR
gene_biotype: protein_coding
description:
  Two-component response regulator; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress.


ensembl_gene_id: BSU33020
symbol: cssS
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase; Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress. Required for the transcription of htrA. Could detect misfolded proteins at the membrane-cell wall interface and then activate CssR by phosphorylation.


ensembl_gene_id: BSU33029
symbol: yuzO
gene_biotype: protein_coding
description:
  Regulator of SpxA degradation; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.


ensembl_gene_id: BSU33040
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: BSU33050
symbol: gerAA
gene_biotype: protein_coding
description:
  Component of the GerA germination receptor; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence.


ensembl_gene_id: BSU33060
symbol: gerAB
gene_biotype: protein_coding
description:
  Component of the germination receptor GerA; Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence.


ensembl_gene_id: BSU33070
symbol: gerAC
gene_biotype: protein_coding
description:
  Component of the germination receptor GerA; Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of GerD and GerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence.


ensembl_gene_id: BSU33080
symbol: liaR
gene_biotype: protein_coding
description:
  Two-component response regulator [YvqE] responding to cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. LiaR regulates the transcription of the liaIHGFSR operon.


ensembl_gene_id: BSU33090
symbol: liaS
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YvqC] sensing cell wall stress; Member of the two-component regulatory system LiaS/LiaR probably involved in response to a subset of cell wall-active antibiotics that interfere with the lipid II cycle in the cytoplasmic membrane (bacitracin, nisin, ramoplanin and vancomycin). Seems also involved in response to cationic antimicrobial peptides and secretion stress. Activates probably LiaR by phosphorylation.


ensembl_gene_id: BSU33100
symbol: liaF
gene_biotype: protein_coding
description:
  Integral inner membrane protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type m: membrane component.


ensembl_gene_id: BSU33110
symbol: liaG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein (response to antibiotic stress); Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187.


ensembl_gene_id: BSU33120
symbol: liaH
gene_biotype: protein_coding
description:
  Modulator of liaIHGFSR (yvqIHGFEC) operon expression; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU33130
symbol: liaI
gene_biotype: protein_coding
description:
  Permease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter.


ensembl_gene_id: BSU33140
symbol: yvqJ
gene_biotype: protein_coding
description:
  Putative efflux protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU33150
symbol: pduO
gene_biotype: protein_coding
description:
  Putative ATP:cob(I)alamin adenosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e: enzyme.


ensembl_gene_id: BSU33160
symbol: yvrA
gene_biotype: protein_coding
description:
  Putative vitamin B12 transport system, ATPase component; Probably part of an ABC transporter complex. Probably responsible for energy coupling to the transport system (By similarity).


ensembl_gene_id: BSU33170
symbol: yvrB
gene_biotype: protein_coding
description:
  Putative vitamin B12 permease; Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane (By similarity).


ensembl_gene_id: BSU33200
symbol: yvrE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the SMP-30/CGR1 family.


ensembl_gene_id: BSU33210
symbol: yvrG
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase YvrG innvolved in cell wall processes [YvrH]; Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA-yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX-rsiX), and negatively regulates the lytABC operon. Probably activates YvrH by phosphorylation.


ensembl_gene_id: BSU33221
symbol: yvrH
gene_biotype: protein_coding
description:
  Two-component response regulator YvrH involved in cell wall processes [YvrG]; Member of the two-component regulatory system YvrG/YvrH that positively regulates 7 transcriptional units (wprA, wapA-yxxG, dltABCDE, sunA, sunT-bdbA-yolJ-bdbB, sigO-rsoA, and sigX-rsiX), and negatively regulates the lytABC operon.


ensembl_gene_id: BSU33222
symbol: rsoA
gene_biotype: protein_coding
description:
  Regulator of sigma-O; Together with RNA polymerase sigma factor SigO, positively regulates the expression of at least three operons, including oxdC- yvrL, sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC.


ensembl_gene_id: BSU33230
symbol: sigO
gene_biotype: protein_coding
description:
  Alternative sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Together with its coactivator RsoA, positively regulates the expression of at least three operons, including oxdC-yvrL, sigO-rsoA and yvrJ. Required for the acid stress-dependent induction of the oxalate decarboxylase oxdC.


ensembl_gene_id: BSU33239
symbol: yvrJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 18573182, 19047353.


ensembl_gene_id: BSU33240
symbol: oxdC
gene_biotype: protein_coding
description:
  Oxalate decarboxylase; Converts oxalate to formate and CO(2) in an O(2)-dependent reaction. Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2), and oxalate-dependent, H(2)O(2)-independent dye oxidations.


ensembl_gene_id: BSU33250
symbol: yvrL
gene_biotype: protein_coding
description:
  Putative integral inner membrane protein; Negatively regulates RNA polymerase sigma factor SigO- dependent transcription. Prevents the expression or secretion of OxdC under nonstress conditions. May act as an anti-sigma factor.


ensembl_gene_id: BSU33270
symbol: yvrO
gene_biotype: protein_coding
description:
  Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU33290
symbol: fhuC
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter (ATP-binding protein); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system (By similarity); Belongs to the ABC transporter superfamily. Iron (Fe3+)- hydroxamate importer (TC 3.A.1.14.7) family.


ensembl_gene_id: BSU33300
symbol: fhuG
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter (permease); Part of the ABC transporter complex FhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane (By similarity).


ensembl_gene_id: BSU33320
symbol: fhuD
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter (ferrichrome-binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen.


ensembl_gene_id: BSU33330
symbol: lysP
gene_biotype: protein_coding
description:
  Lysine permease; Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.


ensembl_gene_id: BSU33360
symbol: ltaSP
gene_biotype: protein_coding
description:
  Primase of polyglycerolphosphate lipoteichoic acid (LTA) synthesis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the LTA synthase family.


ensembl_gene_id: BSU33370
symbol: yvgK
gene_biotype: protein_coding
description:
  Putative molybdate binding regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU33380
symbol: yvgL
gene_biotype: protein_coding
description:
  Putative molybdate-binding lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.


ensembl_gene_id: BSU33390
symbol: yvgM
gene_biotype: protein_coding
description:
  Putative molybdenum transport permease; could be part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BSU33400
symbol: yvgN
gene_biotype: protein_coding
description:
  Glyoxal/methylglyoxal reductase; Reduces glyoxal and methylglyoxal (2-oxopropanal). Is not involved in the vitamin B6 biosynthesis; Belongs to the aldo/keto reductase family.


ensembl_gene_id: BSU33410
symbol: yvgO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11988534.


ensembl_gene_id: BSU33430
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase (hemoprotein beta-subunit); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate (Probable); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: BSU33440
symbol: cysJ
gene_biotype: protein_coding
description:
  Sulfite reductase (flavoprotein alpha-subunit); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component (Probable).


ensembl_gene_id: BSU33450
symbol: helD
gene_biotype: protein_coding
description:
  DNA 3'-5' helicase IV; Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP.


ensembl_gene_id: BSU33470
symbol: bdbC
gene_biotype: protein_coding
description:
  Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168, although it can partially substitute for BdbB when the latter is absent. It may also be required for the stability of other secreted proteins. Not required for sporulation; Belongs to the DsbB family. BdbC subfamily.


ensembl_gene_id: BSU33480
symbol: bdbD
gene_biotype: protein_coding
description:
  Thiol-disulfide oxidoreductase; Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. May be required for the stability of secreted proteins with disulfide bonds. Not required for sporulation.


ensembl_gene_id: BSU33490
symbol: copB
gene_biotype: protein_coding
description:
  copper(I)-transporting ATPase; Couples the hydrolysis of ATP with the transport of cadmium, zinc and cobalt out of the cell. Does not seem to transport copper.


ensembl_gene_id: BSU33510
symbol: copZ
gene_biotype: protein_coding
description:
  Copper insertion chaperone and transporter component; Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA. Functions in E.coli to transfer Cu(+) to CopA missing its first metal-binding domain.


ensembl_gene_id: BSU33520
symbol: csoR
gene_biotype: protein_coding
description:
  Repressor of copper utilisation proteins; Copper-sensitive repressor that has a key role in copper homeostasis. Negatively regulates expression of the copZA operon and of ycnJ. In the absence of copper ions, binds with high affinity to the copZA promoter and represses the transcription. In the presence of copper ions, CsoR binds Cu(1+), which significantly decreases its DNA binding affinity and leads to the transcription of the genes.


ensembl_gene_id: BSU33530
symbol: yvaA
gene_biotype: protein_coding
description:
  Putative oxidoreductase; Catalyzes the reversible NADPH-dependent reduction of scyllo- inosose (SIS) to scyllo-inositol (SI). Cannot use NADH instead of NADPH. May be involved in reduction of not only SIS but also various oxidized compounds manifested upon stressful conditions.


ensembl_gene_id: BSU33540
symbol: yvaB
gene_biotype: protein_coding
description:
  NADH:dichloroindophenol oxidoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity. Confers resistance to catechol, 2- methylhydroquinone (2-MHQ), and diamide. Probably could also reduce benzoquinones produce by the auto-oxidation of catechol and 2- methylhydroquinone.


ensembl_gene_id: BSU33570
symbol: yvaE
gene_biotype: protein_coding
description:
  Putative metabolite-efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.


ensembl_gene_id: BSU33600
symbol: smpB
gene_biotype: protein_coding
description:
  tmRNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches t [...]


ensembl_gene_id: BSU33610
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: BSU33620
symbol: yvaK
gene_biotype: protein_coding
description:
  Carboxylesterase; Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones (By similarity).


ensembl_gene_id: BSU33630
symbol: secG
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; Involved in protein export. Participates in an early event of protein translocation (By similarity).


ensembl_gene_id: BSU33660
symbol: rghRA
gene_biotype: protein_coding
description:
  Transcriptional repressor; Represses the expression of yvaM and both rapG and rapH. Binds directly to the promoter regions of yvaM, rapG and rapH.


ensembl_gene_id: BSU33670
symbol: rghRB
gene_biotype: protein_coding
description:
  Putative transcriptional repressor; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.


ensembl_gene_id: BSU33690
symbol: yvaQ
gene_biotype: protein_coding
description:
  Putative methyl-accepting transducer; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Attractants increase the level of methylation while repellents decrease the level of methylation (By similarity).


ensembl_gene_id: BSU33700
symbol: opuBD
gene_biotype: protein_coding
description:
  Choline ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for choline; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU33710
symbol: opuBC
gene_biotype: protein_coding
description:
  Choline ABC transporter (choline-binding lipoprotein); Member of a high affinity multicomponent binding-protein- dependent transport system for choline.


ensembl_gene_id: BSU33730
symbol: opuBA
gene_biotype: protein_coding
description:
  Choline ABC transporter (ATP-binding protein); Involved in a high affinity multicomponent binding-protein- dependent transport system for choline. Probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU33740
symbol: yvaV
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator; Belongs to the GbsR family.


ensembl_gene_id: BSU33750
symbol: sdpA
gene_biotype: protein_coding
description:
  Export of killing factor; Required for the maturation of SdpC to SDP. Not required for SdpC signal peptide cleavage, secretion from the cell or disulfide bond formation.


ensembl_gene_id: BSU33760
symbol: sdpB
gene_biotype: protein_coding
description:
  Exporter of killing factor SpbC; Required for the maturation of SdpC to SDP. Not required for SdpC signal peptide cleavage, secretion from the cell or disulfide bond formation.


ensembl_gene_id: BSU33770
symbol: spbC
gene_biotype: protein_coding
description:
  Killing factor SdpC; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel. Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation. Addition of SDP to liquid cultures halts growth [...]


ensembl_gene_id: BSU33780
symbol: sdpI
gene_biotype: protein_coding
description:
  Integral membrane regulator of autophagy; Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane.


ensembl_gene_id: BSU33790
symbol: sdpR
gene_biotype: protein_coding
description:
  Transcriptional regulator (ArsR family); Represses the transcription of the sdpIR operon and of several other operons that probably contribute to delaying commitment to sporulation.


ensembl_gene_id: BSU33800
symbol: opuCD
gene_biotype: protein_coding
description:
  Glycine betaine/carnitine/choline/choline sulfate ABC transporter (permease); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: BSU33810
symbol: opuCC
gene_biotype: protein_coding
description:
  Glycine betaine/carnitine/choline-binding protein OpuCC; Member of a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine, and choline. Belongs to the OsmX family.


ensembl_gene_id: BSU33830
symbol: opuCA
gene_biotype: protein_coding
description:
  Glycine betaine/carnitine/choline/choline sulfate ABC transporter (ATP-binding protein); Involved in a high affinity multicomponent binding-protein- dependent transport system for glycine betaine, carnitine and choline; probably responsible for energy coupling to the transport system.


ensembl_gene_id: BSU33840
symbol: yvbF
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Negatively regulates the transcription of the opuC operon. In the absence of GbsR, is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons.


ensembl_gene_id: BSU33880
symbol: yvbJ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15155184.


ensembl_gene_id: BSU33900
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: BSU33910
symbol: pgm
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.


ensembl_gene_id: BSU33920
symbol: tpiA
gene_biotype: protein_coding
description:
  Triose phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: BSU33930
symbol: pgk
gene_biotype: protein_coding
description:
  Phosphoglycerate kinase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: BSU33940
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase; Involved in the glycolysis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3- bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.


ensembl_gene_id: BSU33950
symbol: cggR
gene_biotype: protein_coding
description:
  Transcriptional regulator of gapA; In the absence of glucose, represses the transcription of the gapA operon, which encodes five key glycolytic enzymes. Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase, leading to the arrest of the transcription; Belongs to the SorC transcriptional regulatory family.


ensembl_gene_id: BSU33960
symbol: araE
gene_biotype: protein_coding
description:
  Arabinose-related compounds permease; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system).


ensembl_gene_id: BSU33970
symbol: araR
gene_biotype: protein_coding
description:
  Transcriptional repressor of the ara regulon (LacI family); Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter.


ensembl_gene_id: BSU34000
symbol: cyeB
gene_biotype: protein_coding
description:
  Cysteine and O-acetylserine efflux permease; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.


ensembl_gene_id: BSU34010
symbol: yvbW
gene_biotype: protein_coding
description:
  Putative leucine permease; May participate in leucine metabolism. May transport leucine or a compound related to leucine metabolism; Belongs to the amino acid-polyamine-organocation (APC) superfamily.


ensembl_gene_id: BSU34020
symbol: yvbX
gene_biotype: protein_coding
description:
  Putative epimerase modification of peptidoglycan; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: BSU34030
symbol: lutC
gene_biotype: protein_coding
description:
  Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present.


ensembl_gene_id: BSU34040
symbol: lutB
gene_biotype: protein_coding
description:
  Component of an iron-sulfur oxidase; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present.


ensembl_gene_id: BSU34050
symbol: lutA
gene_biotype: protein_coding
description:
  Iron-sulfur oxidase component; Is essential for L-lactate degradation and allows cells to grow with lactate as the sole carbon source. May also allow cells to utilize an alternative carbon source during biofilm formation, since it contributes to the formation of architecturally complex communities when lactate is present.


ensembl_gene_id: BSU34070
symbol: yvfT
gene_biotype: protein_coding
description:
  Two-component sensor histidine kinase [YvfU]; Member of the two-component regulatory system YvfT/YvfU. Probably activates YvfU by phosphorylation.


ensembl_gene_id: BSU34090
symbol: yvfR
gene_biotype: protein_coding
description:
  Putative ABC efflux transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.


ensembl_gene_id: BSU34100
symbol: rsbQ
gene_biotype: protein_coding
description:
  Regulator of RsbP phosphatase; Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for RsbP phosphatase activity; Belongs to the AB hydrolase superfamily.


ensembl_gene_id: BSU34110
symbol: rsbP
gene_biotype: protein_coding
description:
  Serine phosphatase; Positive regulator of sigma-B activity. Dephosphorylates RsbV in response to energy stress.


ensembl_gene_id: BSU34120
symbol: ganB
gene_biotype: protein_coding
description:
  Secreted arabinogalactan oligomer endo-hydrolase; Hydrolyzes the beta-1,4-galactan linkages of arabinogalactan type I, a pectic substance found in plants such as soybeans.


ensembl_gene_id: BSU34130
symbol: ganA
gene_biotype: protein_coding
description:
  Arabinogalactan type I oligomer exo-hydrolase (beta-galactosidase, lactase); Hydrolyzes oligosaccharides released by the endo-1,4-beta- galactosidase GalA from arabinogalactan type I, a pectic plant polysaccharide. It is unable to use lactose as a sole carbon source. Maximal activity with o-nitrophenyl-beta-D-galactopyranoside (ONPG) and p-nitrophenyl-beta-D-galactopyranoside (PNPG) as substrates, trace activity with p-nitrophenyl-alpha-L-arabinopyranoside and o- nitrophenyl-beta-D-fucopyranoside as substrates, but no activity with p-nitrophenyl-alpha-D-galactopyranoside, p-nitrophenyl [...]


ensembl_gene_id: BSU34140
symbol: ganQ
gene_biotype: protein_coding
description:
  Arabinogalactan oligomer permease; Could be part of a binding-protein-dependent transport system for arabinogalactan oligomers; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: BSU34160
symbol: cycB
gene_biotype: protein_coding
description:
  Cyclodextrin-binding lipoprotein; Binding protein for cyclodextrin; involved in its cellular uptake. Interacts with all natural cyclodextrins: alpha, beta and gamma; Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BSU34180
symbol: yvfI
gene_biotype: protein_coding
description:
  Putative transcriptional regulator (GntR family); Negatively regulates the transcription of the lutABC operon, which is required for L-lactate utilization. LutR activity is regulated by lactate, since presence of L-lactate, that probably binds to LutR, leads to derepression of the operon. Also appears to be essential for bacilysin biosynthesis.


ensembl_gene_id: BSU34200
symbol: sigL
gene_biotype: protein_coding
description:
  RNA polymerase sigma-54 factor (sigma-L); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the levanase operon. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein LevR for the expression of the levanase operon.


ensembl_gene_id: BSU34220
symbol: epsO
gene_biotype: protein_coding
description:
  Putative pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the polysaccharide pyruvyl transferase family.


ensembl_gene_id: BSU34230
symbol: epsN
gene_biotype: protein_coding
description:
  Putative aminotransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles.


ensembl_gene_id: BSU34240
symbol: epsM
gene_biotype: protein_coding
description:
  Putative O-acetyltransferase; Catalyzes the conversion of UDP-2,4,6-trideoxy-2-acetamido-4- amino glucose to UDP-2,4,6-trideoxy-2,4-diacetamido glucose, commonly known as UDP-N,N'-diacetylbacillosamine (UDP-diNAcBac). Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: BSU34250
symbol: epsL
gene_biotype: protein_coding
description:
  Putative phosphotransferase involved in extracellular matrix synthesis; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles.


ensembl_gene_id: BSU34265
symbol: epsK
gene_biotype: protein_coding
description:
  Putative extracellular matrix component exporter; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles.


ensembl_gene_id: BSU34280
symbol: epsJ
gene_biotype: protein_coding
description:
  Putative glycosyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the glycosyltransferase 2 family.


ensembl_gene_id: BSU34290
symbol: epsI
gene_biotype: protein_coding
description:
  Putative polysaccharide pyruvyl transferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles; Belongs to the polysaccharide pyruvyl transferase family.


ensembl_gene_id: BSU34300
symbol: epsH
gene_biotype: protein_coding
description:
  Putative glycosyltransferase involved in biofilm formation; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase 2 family.


ensembl_gene_id: BSU34310
symbol: epsG
gene_biotype: protein_coding
description:
  Biofilm extracellular matrix formation enzyme; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance.


ensembl_gene_id: BSU34320
symbol: epsF
gene_biotype: protein_coding
description:
  Putative glycosyltransferase involved in extracellular matrix formation; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.


ensembl_gene_id: BSU34330
symbol: epsE
gene_biotype: protein_coding
description:
  Bifunctional flagellar clutch and glycosyltransferase; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase 2 family.


ensembl_gene_id: BSU34340
symbol: epsD
gene_biotype: protein_coding
description:
  Putative extracellular matrix biosynthesis enzyme; May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation. EPS is responsible for the adhesion of chains of cells into bundles. Required for biofilm maintenance; Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.


ensembl_gene_id: BSU34350
symbol: epsC
gene_biotype: protein_coding
description:
  Putative UDP-sugar epimerase; Involved in biofilm formation; Belongs to the polysaccharide synthase family.


ensembl_gene_id: BSU34360
symbol: epsB
gene_biotype: protein_coding
description:
  Protein tyrosine kinase; Evidence 2b: Function of strongly homologous gene; enzyme; Belongs to the CpsD/CapB family.


ensembl_gene_id: BSU34370
symbol: epsA
gene_biotype: protein_coding
description:
  Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator.


ensembl_gene_id: BSU34380
symbol: slrR
gene_biotype: protein_coding
description:
  Transcriptional regulator of autolysin genes; Represses sigma(D)-dependent flagellar genes and activate the eps and yqxM operons. Repressor activity is regulated by SlrA. Controls the initiation of biofilm formation.


ensembl_gene_id: BSU34390
symbol: pnbA
gene_biotype: protein_coding
description:
  Para-nitrobenzyl esterase (intracellular esterase B); Catalyzes hydrolysis of several beta-lactam antibiotic PNB esters to the corresponding free acid and PNB alcohol; Belongs to the type-B carboxylesterase/lipase family.


ensembl_gene_id: BSU34400
symbol: padC
gene_biotype: protein_coding
description:
  Phenolic acid decarboxylase; Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic, p-coumaric and caffeic acids; Belongs to the PadC family.


ensembl_gene_id: BSU34410
symbol: yveG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0311 family.


ensembl_gene_id: BSU34430
symbol: racX
gene_biotype: protein_coding
description:
  Amino acid racemase; Amino-acid racemase able to utilize a broad range of substrates. Preferentially catalyzes the epimerization of LL- diaminopimelate, as well as the racemization of D-lysine, L-arginine, L-ornithine, L-lysine and D-arginine. Has lower activity against D- ornithine, L-histidine, L-alanine, L-tyrosine, L-phenylalanine, L- serine, L-glutamine, L-methionine, L-asparagine and L-homoserine. Has weak activity against L-norleucine, L-aminobutyric acid and L- norvaline. Has no activity toward nine L-amino acids (Thr, Glu, Asp, Val, Leu, Ile, Trp, Cit and Aad). D-amino acids m [...]


ensembl_gene_id: BSU34440
symbol: pbpE
gene_biotype: protein_coding
description:
  Penicillin-binding protein 4*; Probably involved in peptidoglycan modification during cortex synthesis.


ensembl_gene_id: BSU34450
symbol: sacB
gene_biotype: protein_coding
description:
  Levansucrase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.


ensembl_gene_id: BSU34460
symbol: levB
gene_biotype: protein_coding
description:
  Endolevanase; Catalyzes the degradation of levan mainly into levanbiose (difructose). Is not active on sucrose; Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: BSU34470
symbol: yveA
gene_biotype: protein_coding
description:
  L-aspartate/L-glutamate permease; Uptake of L-aspartate with the concomitant import of a proton. Can also transport aspartate hydroxamate and L-glutamate with lower affinity and efficiency.


ensembl_gene_id: BSU34500
symbol: yvdR
gene_biotype: protein_coding
description:
  Putative membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.


ensembl_gene_id: BSU34520
symbol: yvdP
gene_biotype: protein_coding
description:
  Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the oxygen-dependent FAD-linked oxidoreductase family.


ensembl_gene_id: BSU34530
symbol: cotR
gene_biotype: protein_coding
description:
  Spore coat protein assembly factor CotR; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.


ensembl_gene_id: BSU34540
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a limited peptidase activity in the absence of ATP-binding subunits ClpC, ClpE or ClpX. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcriptional activation of genes under the control of the sigma-W factor. Probably the major protease that degrades prot [...]


ensembl_gene_id: BSU34550
symbol: mdxM
gene_biotype: protein_coding
description:
  Beta-phosphoglucomutase; Catalyzes the interconversion of D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and forming beta-D-glucose 1,6- (bis)phosphate (beta-G16P) as an intermediate. The beta- phosphoglucomutase (Beta-PGM) acts on the beta-C(1) anomer of G1P. It plays a key role in the regulation of the flow of carbohydrate intermediates in glycolysis and the formation of the sugar nucleotide UDP-glucose (By similarity).


ensembl_gene_id: BSU34560
symbol: mdxL
gene_biotype: protein_coding
description:
  Oligo-1,4-1,6-alpha-glucosidase (sucrase-maltase-isomaltase); Hydrolyzes various disaccharides such as sucrose, maltose, and isomaltose with different efficiencies. Also hydrolyzes longer maltodextrins from maltotriose up to maltohexaose, but not maltoheptaose, palatinose, isomaltotriose, or isomaltotetraose. Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: BSU34570
symbol: mdxK
gene_biotype: protein_coding
description:
  Maltose phosphorylase; Catalyzes the phosphorolysis of maltose, leading to the formation of glucose and glucose 1-P.


ensembl_gene_id: BSU34590
symbol: mdxG
gene_biotype: protein_coding
description:
  Maltodextrin ABC transporter (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable).


ensembl_gene_id: BSU34600
symbol: mdxF
gene_biotype: protein_coding
description:
  Maltodextrin ABC transport system (permease); Part of the ABC transporter complex involved in maltodextrin import. Probably responsible for the translocation of the substrate across the membrane (Probable).


ensembl_gene_id: BSU34610
symbol: mdxE
gene_biotype: protein_coding
description:
  Maltose/maltodextrin-binding lipoprotein; Part of the ABC transporter complex involved in maltodextrin import. Binds maltodextrin. Can also bind maltose with low affinity, but is not involved in its uptake; Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: BSU34620
symbol: mdxD
gene_biotype: protein_coding
description:
  Maltogenic alpha-amylase; Hydrolyzes beta-cyclodextrin to maltose and glucose, soluble starch to maltose and glucose, and pullulan to panose with trace amounts of maltose and glucose. It is also able to hydrolyze acarbose. Can also exhibit a transglycosylation activity transferring glucose or maltose to another moiety of sugars by forming alpha-(1,6)- and alpha- (1,3)-glycosidic linkages upon the hydrolysis of substrate at concentrations of 5% or higher (By similarity); Belongs to the glycosyl hydrolase 13 family. BbmA subfamily.


ensembl_gene_id: BSU34630
symbol: mdxR
gene_biotype: protein_coding
description:
  Transcriptional activator of the maltodextrin operon (LacI family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type pr: putative regulator.


ensembl_gene_id: BSU34640
symbol: yvdD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the LOG family.


ensembl_gene_id: BSU34650
symbol: yvdC
gene_biotype: protein_coding
description:
  Putative pyrophosphohydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.


