# geneInfo

ensembl_gene_id: NAP1_00020
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: NAP1_00025
symbol: EAQ29111.1
gene_biotype: protein_coding
description:
  Putative long-chain fatty-acid-CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.


ensembl_gene_id: NAP1_00045
symbol: EAQ29115.1
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: NAP1_00065
symbol: EAQ29119.1
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase; COG3605 Signal transduction protein containing GAF and PtsI domains; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: NAP1_00085
symbol: tilS
gene_biotype: protein_coding
description:
  ATPase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.


ensembl_gene_id: NAP1_00095
symbol: EAQ29125.1
gene_biotype: protein_coding
description:
  Putative phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.


ensembl_gene_id: NAP1_00105
symbol: edd
gene_biotype: protein_coding
description:
  Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: NAP1_00110
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: NAP1_00120
symbol: rimO
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: NAP1_00135
symbol: surE
gene_biotype: protein_coding
description:
  Stationary-phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: NAP1_00140
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: NAP1_00195
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: NAP1_00240
symbol: EAQ29154.1
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: NAP1_00250
symbol: der
gene_biotype: protein_coding
description:
  Predicted GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: NAP1_00260
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: NAP1_00275
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: NAP1_00280
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: NAP1_00310
symbol: EAQ29168.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: NAP1_00320
symbol: mtgA
gene_biotype: protein_coding
description:
  Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: NAP1_00325
symbol: EAQ29171.1
gene_biotype: protein_coding
description:
  Putative sphingosine-1-phosphate lyase; COG0076 Glutamate decarboxylase and related PLP-dependent proteins.


ensembl_gene_id: NAP1_00350
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: NAP1_00355
symbol: EAQ29177.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase D large subunit; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: NAP1_00405
symbol: nhaA
gene_biotype: protein_coding
description:
  Sodium-proton antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: NAP1_00410
symbol: EAQ29188.1
gene_biotype: protein_coding
description:
  Bacteriophage N4 adsorption protein B; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.


ensembl_gene_id: NAP1_00440
symbol: queE
gene_biotype: protein_coding
description:
  Coenzyme PQQ synthesis protein, conjectural; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: NAP1_00450
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: NAP1_00465
symbol: EAQ29199.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component.


ensembl_gene_id: NAP1_00470
symbol: EAQ29200.1
gene_biotype: protein_coding
description:
  COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component.


ensembl_gene_id: NAP1_00495
symbol: EAQ29205.1
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: NAP1_00500
symbol: ccrB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: NAP1_00515
symbol: gatC
gene_biotype: protein_coding
description:
  Putative glutamyl-trna(gln) amidotransferase subunit c protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: NAP1_00520
symbol: gatA
gene_biotype: protein_coding
description:
  glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: NAP1_00530
symbol: gatB
gene_biotype: protein_coding
description:
  glutamyl-tRNA(gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: NAP1_00565
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: NAP1_00610
symbol: EAQ29228.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_00615
symbol: EAQ29229.1
gene_biotype: protein_coding
description:
  Cell wall endopeptidase, family M23/M37; COG0739 Membrane proteins related to metalloendopeptidases.


ensembl_gene_id: NAP1_00665
symbol: EAQ29239.1
gene_biotype: protein_coding
description:
  Type II secretion system protein; COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.


ensembl_gene_id: NAP1_00705
symbol: thrB
gene_biotype: protein_coding
description:
  COG2334 Putative homoserine kinase type II (protein kinase fold); Belongs to the pseudomonas-type ThrB family.


ensembl_gene_id: NAP1_00710
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: NAP1_00735
symbol: EAQ29253.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: NAP1_00740
symbol: EAQ29254.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: NAP1_00745
symbol: tatA
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: NAP1_00750
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: NAP1_00755
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein secretion pathway component; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: NAP1_00770
symbol: EAQ29260.1
gene_biotype: protein_coding
description:
  Dehydrogenase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: NAP1_00780
symbol: bpt
gene_biotype: protein_coding
description:
  arginyl-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: NAP1_00800
symbol: EAQ29266.1
gene_biotype: protein_coding
description:
  Putative potassium uptake protein, TrkA family protein; COG0569 K+ transport systems, NAD-binding component.


ensembl_gene_id: NAP1_00835
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: NAP1_00855
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: NAP1_00870
symbol: EAQ29280.1
gene_biotype: protein_coding
description:
  ABC-type transport system permease component; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: NAP1_00875
symbol: ccmA
gene_biotype: protein_coding
description:
  ABC-type transport system ATPase component; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: NAP1_00885
symbol: EAQ29283.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_00905
symbol: EAQ29287.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family/hydrolase, alpha/beta fold family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: NAP1_00945
symbol: rsmH
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: NAP1_00960
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: NAP1_00965
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl pentapeptide synthase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: NAP1_00970
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: NAP1_00975
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: NAP1_00985
symbol: murG
gene_biotype: protein_coding
description:
  N-acetylglucosaminyl transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: NAP1_01005
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: NAP1_01010
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: NAP1_01015
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: NAP1_01030
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: NAP1_01050
symbol: obg
gene_biotype: protein_coding
description:
  Predicted GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: NAP1_01055
symbol: proB
gene_biotype: protein_coding
description:
  Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: NAP1_01065
symbol: EAQ29319.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: NAP1_01075
symbol: EAQ29321.1
gene_biotype: protein_coding
description:
  Phosophoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: NAP1_01095
symbol: EAQ29325.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: NAP1_01120
symbol: queF
gene_biotype: protein_coding
description:
  Probable GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.


ensembl_gene_id: NAP1_01130
symbol: EAQ29332.1
gene_biotype: protein_coding
description:
  Outer membrane autotransporter barrel protein; COG3210 Large exoproteins involved in heme utilization or adhesion.


ensembl_gene_id: NAP1_01205
symbol: EAQ29347.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component.


ensembl_gene_id: NAP1_01215
symbol: EAQ29349.1
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: NAP1_01220
symbol: EAQ29350.1
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: NAP1_01250
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: NAP1_01265
symbol: EAQ29359.1
gene_biotype: protein_coding
description:
  RpoE; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: NAP1_01280
symbol: lysA
gene_biotype: protein_coding
description:
  Orn/DAP/Arg decarboxylase, family 2; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: NAP1_01310
symbol: EAQ29368.1
gene_biotype: protein_coding
description:
  Asparaginase family protein; COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D.


ensembl_gene_id: NAP1_01315
symbol: EAQ29369.1
gene_biotype: protein_coding
description:
  Putative Zn-dependent enzyme; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: NAP1_01320
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: NAP1_01325
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: NAP1_01330
symbol: recR
gene_biotype: protein_coding
description:
  Recombinational DNA repair protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: NAP1_01335
symbol: def
gene_biotype: protein_coding
description:
  Polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: NAP1_01350
symbol: EAQ29376.1
gene_biotype: protein_coding
description:
  COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: NAP1_01380
symbol: EAQ29382.1
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: NAP1_01385
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.


ensembl_gene_id: NAP1_01405
symbol: EAQ29387.1
gene_biotype: protein_coding
description:
  Putative thioredoxin reductase; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: NAP1_01480
symbol: EAQ29402.1
gene_biotype: protein_coding
description:
  COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: NAP1_01515
symbol: EAQ29409.1
gene_biotype: protein_coding
description:
  Site-specific DNA-methyltransferase; COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: NAP1_01545
symbol: EAQ29415.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_01570
symbol: EAQ29420.1
gene_biotype: protein_coding
description:
  Probable nad(p) transhydrogenase subunit alpha part 2 transmembrane protein; COG3288 NAD/NADP transhydrogenase alpha subunit.


ensembl_gene_id: NAP1_01575
symbol: EAQ29421.1
gene_biotype: protein_coding
description:
  PntB, NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: NAP1_01610
symbol: EAQ29428.1
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase-like protein; COG0232 dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: NAP1_01645
symbol: EAQ29435.1
gene_biotype: protein_coding
description:
  Putative transporter, RarD family, DMT superfamily protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.


ensembl_gene_id: NAP1_01660
symbol: EAQ29438.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.


ensembl_gene_id: NAP1_01685
symbol: EAQ29443.1
gene_biotype: protein_coding
description:
  flaR protein (flaR); COG3980 Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase.


ensembl_gene_id: NAP1_01695
symbol: EAQ29445.1
gene_biotype: protein_coding
description:
  DegT/DnrJ/EryC1/StrS aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: NAP1_01700
symbol: EAQ29446.1
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthesis protein; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: NAP1_01705
symbol: EAQ29447.1
gene_biotype: protein_coding
description:
  Putative polysaccharide biosynthesis protein CpsL; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: NAP1_01720
symbol: glmS
gene_biotype: protein_coding
description:
  D-fructose-6-phosphate amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: NAP1_01730
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase I (FGAM) synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is tho [...]


ensembl_gene_id: NAP1_01735
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase small subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]


ensembl_gene_id: NAP1_01745
symbol: EAQ29455.1
gene_biotype: protein_coding
description:
  Peptidase, M16 family protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.


ensembl_gene_id: NAP1_01755
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: NAP1_01760
symbol: yacG
gene_biotype: protein_coding
description:
  Zinc-binding protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: NAP1_01770
symbol: EAQ29460.1
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: NAP1_01775
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor 1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: NAP1_01805
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: NAP1_01830
symbol: EAQ29472.1
gene_biotype: protein_coding
description:
  Manganese and iron superoxide dismutase (SODM); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: NAP1_01845
symbol: EAQ29475.1
gene_biotype: protein_coding
description:
  Possible polysaccharide export protein; Similar to GenBank Accession Number AF040104; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: NAP1_01865
symbol: hppA
gene_biotype: protein_coding
description:
  Membrane-bound proton-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: NAP1_01870
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: NAP1_01875
symbol: nusB
gene_biotype: protein_coding
description:
  Transcription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: NAP1_01880
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: NAP1_01885
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.


ensembl_gene_id: NAP1_01900
symbol: EAQ29486.1
gene_biotype: protein_coding
description:
  Probable hydrolase protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: NAP1_01905
symbol: EAQ29487.1
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-[acyl-carrier protein] reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_01915
symbol: EAQ29489.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: NAP1_01960
symbol: EAQ29498.1
gene_biotype: protein_coding
description:
  Penicillin-binding protein, 1A family protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).


ensembl_gene_id: NAP1_01990
symbol: EAQ29504.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis).


ensembl_gene_id: NAP1_02005
symbol: acpS
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: NAP1_02015
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthesis protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: NAP1_02020
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: NAP1_02025
symbol: EAQ29511.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: NAP1_02030
symbol: EAQ29512.1
gene_biotype: protein_coding
description:
  Cytochrome-c oxidase chain I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: NAP1_02035
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: NAP1_02045
symbol: ctaG
gene_biotype: protein_coding
description:
  Cytochrome-c oxidase assembly protein; Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I; Belongs to the COX11/CtaG family.


ensembl_gene_id: NAP1_02085
symbol: moaA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: NAP1_02105
symbol: EAQ29527.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: NAP1_02115
symbol: rplU
gene_biotype: protein_coding
description:
  Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: NAP1_02125
symbol: EAQ29531.1
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family protein; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: NAP1_02140
symbol: EAQ29534.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: NAP1_02160
symbol: EAQ29538.1
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: NAP1_02215
symbol: EAQ29549.1
gene_biotype: protein_coding
description:
  Glutamate-cysteine ligase precursor; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.


ensembl_gene_id: NAP1_02220
symbol: EAQ29550.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: NAP1_02230
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: NAP1_02280
symbol: EAQ29562.1
gene_biotype: protein_coding
description:
  Prolyl 4-hydroxylase, alpha subunit; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: NAP1_02365
symbol: EAQ29579.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: NAP1_02405
symbol: EAQ29587.1
gene_biotype: protein_coding
description:
  Bacterial sugar transferase/glycosyl transferase, WecB/TagA/CpsF family protein; COG1922 Teichoic acid biosynthesis proteins.


ensembl_gene_id: NAP1_02450
symbol: EAQ29596.1
gene_biotype: protein_coding
description:
  LUXO_VIBHA Repressor protein luxO; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: NAP1_02510
symbol: EAQ29608.1
gene_biotype: protein_coding
description:
  AccC, acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: NAP1_02515
symbol: EAQ29609.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: NAP1_02520
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: NAP1_02545
symbol: yajC
gene_biotype: protein_coding
description:
  Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: NAP1_02550
symbol: secD
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: NAP1_02650
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: NAP1_02655
symbol: EAQ29637.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: NAP1_02665
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: NAP1_02670
symbol: EAQ29640.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: NAP1_02715
symbol: EAQ29649.1
gene_biotype: protein_coding
description:
  Two-component system regulatory protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: NAP1_02720
symbol: EAQ29650.1
gene_biotype: protein_coding
description:
  NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_02740
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: NAP1_02745
symbol: EAQ29655.1
gene_biotype: protein_coding
description:
  COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: NAP1_02760
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: NAP1_02775
symbol: EAQ29661.1
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase family protein; COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.


ensembl_gene_id: NAP1_02785
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: NAP1_02790
symbol: EAQ29664.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: NAP1_02800
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: NAP1_02810
symbol: bamA
gene_biotype: protein_coding
description:
  Outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: NAP1_02820
symbol: fabZ
gene_biotype: protein_coding
description:
  (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: NAP1_02845
symbol: EAQ29675.1
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: NAP1_02850
symbol: ccmC
gene_biotype: protein_coding
description:
  ABC-type transport system heme exporter; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: NAP1_02855
symbol: EAQ29677.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: NAP1_02860
symbol: ccmE
gene_biotype: protein_coding
description:
  CcmE/CycJ proteins; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: NAP1_02885
symbol: kup
gene_biotype: protein_coding
description:
  K+ transporter; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: NAP1_02890
symbol: EAQ29684.1
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: NAP1_02895
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: NAP1_02905
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: NAP1_02910
symbol: EAQ29688.1
gene_biotype: protein_coding
description:
  Sensory box/GGDEF family protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: NAP1_02920
symbol: EAQ29690.1
gene_biotype: protein_coding
description:
  Probable short chain protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_02930
symbol: EAQ29692.1
gene_biotype: protein_coding
description:
  Acetolactate synthase large subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: NAP1_02940
symbol: EAQ29694.1
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: NAP1_02945
symbol: EAQ29695.1
gene_biotype: protein_coding
description:
  COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: NAP1_02960
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: NAP1_02965
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: NAP1_02980
symbol: EAQ29702.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: NAP1_02995
symbol: EAQ29705.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: NAP1_03000
symbol: mltG
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: NAP1_03010
symbol: EAQ29708.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding domain protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: NAP1_03025
symbol: EAQ29711.1
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: NAP1_03050
symbol: EAQ29716.1
gene_biotype: protein_coding
description:
  Regulatory protein; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: NAP1_03060
symbol: EAQ29718.1
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein, MerR family protein; COG0789 Predicted transcriptional regulators.


ensembl_gene_id: NAP1_03115
symbol: EAQ29729.1
gene_biotype: protein_coding
description:
  Site-specific recombinase, phage integrase family protein; COG0582 Integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: NAP1_03250
symbol: EAQ29756.1
gene_biotype: protein_coding
description:
  Putative acriflavin resistance protein D; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: NAP1_03330
symbol: EAQ29772.1
gene_biotype: protein_coding
description:
  TrwC protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: NAP1_03355
symbol: EAQ29777.1
gene_biotype: protein_coding
description:
  Prophage MuMc02, peptidase, family S24; COG2932 Predicted transcriptional regulator; Belongs to the peptidase S24 family.


ensembl_gene_id: NAP1_03440
symbol: EAQ29794.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: NAP1_03510
symbol: EAQ29808.1
gene_biotype: protein_coding
description:
  Metal ion efflux RND protein family protein; COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: NAP1_03535
symbol: EAQ29813.1
gene_biotype: protein_coding
description:
  Heavy metal RND efflux membrane fusion protein, CzcB family protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: NAP1_03540
symbol: EAQ29814.1
gene_biotype: protein_coding
description:
  Heavy metal efflux pump CzcA; COG3696 Putative silver efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: NAP1_03620
symbol: EAQ29830.1
gene_biotype: protein_coding
description:
  Sigma-24 (FecI-like); COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: NAP1_03750
symbol: EAQ29856.1
gene_biotype: protein_coding
description:
  Putative metabolite exporter, AcrB/D/F family protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: NAP1_03760
symbol: EAQ29858.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: NAP1_03770
symbol: EAQ29860.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: NAP1_03830
symbol: EAQ29872.1
gene_biotype: protein_coding
description:
  Trehalose-6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.


ensembl_gene_id: NAP1_03845
symbol: EAQ29875.1
gene_biotype: protein_coding
description:
  Phosphate regulon transcriptional regulatory protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: NAP1_03870
symbol: EAQ29880.1
gene_biotype: protein_coding
description:
  S-adenosylmethionine-diacylgycerolhomoserine-N- methlytransferase; COG0500 SAM-dependent methyltransferases.


ensembl_gene_id: NAP1_03895
symbol: EAQ29885.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: NAP1_03900
symbol: EAQ29886.1
gene_biotype: protein_coding
description:
  Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.


ensembl_gene_id: NAP1_03955
symbol: plsY
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: NAP1_03960
symbol: EAQ29898.1
gene_biotype: protein_coding
description:
  DNA processing chain A; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: NAP1_03965
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: NAP1_03985
symbol: era
gene_biotype: protein_coding
description:
  GTPase; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: NAP1_03990
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: NAP1_04020
symbol: EAQ29910.1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: NAP1_04070
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: NAP1_04105
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthetase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: NAP1_04110
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: NAP1_04120
symbol: xerC
gene_biotype: protein_coding
description:
  Integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: NAP1_04125
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: NAP1_04145
symbol: EAQ29935.1
gene_biotype: protein_coding
description:
  Mutator mutT protein; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: NAP1_04170
symbol: EAQ29940.1
gene_biotype: protein_coding
description:
  AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: NAP1_04180
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosylhomocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: NAP1_04200
symbol: EAQ29946.1
gene_biotype: protein_coding
description:
  Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: NAP1_04210
symbol: EAQ29948.1
gene_biotype: protein_coding
description:
  COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains).


ensembl_gene_id: NAP1_04215
symbol: EAQ29949.1
gene_biotype: protein_coding
description:
  COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: NAP1_04220
symbol: EAQ29950.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.


ensembl_gene_id: NAP1_04225
symbol: EAQ29951.1
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: NAP1_04230
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: NAP1_04240
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: NAP1_04315
symbol: nadK
gene_biotype: protein_coding
description:
  Predicted sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: NAP1_04330
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: NAP1_04350
symbol: EAQ29976.1
gene_biotype: protein_coding
description:
  COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: NAP1_04360
symbol: EAQ29978.1
gene_biotype: protein_coding
description:
  Putative ubiquinol-cytochrome-c reductase assembly protein; COG0661 Predicted unusual protein kinase.


ensembl_gene_id: NAP1_04370
symbol: EAQ29980.1
gene_biotype: protein_coding
description:
  Possible oxoacyl carrier protein reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_04380
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: NAP1_04385
symbol: EAQ29983.1
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase alpha subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: NAP1_04390
symbol: EAQ29984.1
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase (beta subunit); COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: NAP1_04395
symbol: EAQ29985.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: NAP1_04430
symbol: EAQ29992.1
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: NAP1_04450
symbol: EAQ29996.1
gene_biotype: protein_coding
description:
  COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: NAP1_04485
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: NAP1_04490
symbol: EAQ30004.1
gene_biotype: protein_coding
description:
  Elongation factor P; COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit.


ensembl_gene_id: NAP1_04495
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: NAP1_04545
symbol: EAQ30015.1
gene_biotype: protein_coding
description:
  Two Component Transcriptional Regulator, Fis family protein; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: NAP1_04560
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: NAP1_04565
symbol: EAQ30019.1
gene_biotype: protein_coding
description:
  Sodium-dependent transporter, NSS family protein; COG0733 Na+-dependent transporters of the SNF family.


ensembl_gene_id: NAP1_04600
symbol: dnaE2
gene_biotype: protein_coding
description:
  DNA polymerase III subunit alpha; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: NAP1_04620
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: NAP1_04630
symbol: EAQ30032.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: NAP1_04680
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: NAP1_04695
symbol: EAQ30045.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.


ensembl_gene_id: NAP1_04725
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: NAP1_04735
symbol: EAQ30053.1
gene_biotype: protein_coding
description:
  Acetolactate synthase III large subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: NAP1_04740
symbol: miaA
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate:tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: NAP1_04765
symbol: EAQ30059.1
gene_biotype: protein_coding
description:
  Putative Uncharacterized protein involved in ubiquinone biosynthesis; COG1220 ATP-dependent protease HslVU (ClpYQ), ATPase subunit.


ensembl_gene_id: NAP1_04780
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]


ensembl_gene_id: NAP1_04795
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: NAP1_04800
symbol: EAQ30066.1
gene_biotype: protein_coding
description:
  Geranyltranstransferase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: NAP1_04805
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: NAP1_04810
symbol: EAQ30068.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: NAP1_04815
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA-ribosyltransferase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: NAP1_04820
symbol: EAQ30070.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: NAP1_04830
symbol: tgt
gene_biotype: protein_coding
description:
  tRNA guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]


ensembl_gene_id: NAP1_04840
symbol: EAQ30074.1
gene_biotype: protein_coding
description:
  Hypothetical oxidoreductase; COG2249 Putative NADPH-quinone reductase (modulator of drug activity B).


ensembl_gene_id: NAP1_04845
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: NAP1_04860
symbol: trmJ
gene_biotype: protein_coding
description:
  rRNA methylase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: NAP1_04865
symbol: nrdR
gene_biotype: protein_coding
description:
  Hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: NAP1_04875
symbol: glyA
gene_biotype: protein_coding
description:
  Probable serine hydroxymethyltransferase protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: NAP1_04895
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: NAP1_04900
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: NAP1_04935
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: NAP1_04970
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: NAP1_04985
symbol: ribH
gene_biotype: protein_coding
description:
  Riboflavin synthase beta-chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: NAP1_04990
symbol: ribB
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: NAP1_05005
symbol: EAQ30107.1
gene_biotype: protein_coding
description:
  Two-component transcriptional regulator, LuxR family protein; COG2771 DNA-binding HTH domain-containing proteins.


ensembl_gene_id: NAP1_05010
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: NAP1_05035
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair enzyme; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: NAP1_05055
symbol: ychF
gene_biotype: protein_coding
description:
  GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: NAP1_05065
symbol: EAQ30119.1
gene_biotype: protein_coding
description:
  Probable dehydrogenase/ reductase 7; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_05075
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: NAP1_05085
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: NAP1_05105
symbol: EAQ30127.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1593 TRAP-type C4-dicarboxylate transport system, large permease component.


ensembl_gene_id: NAP1_05160
symbol: EAQ30138.1
gene_biotype: protein_coding
description:
  Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: NAP1_05175
symbol: hisI
gene_biotype: protein_coding
description:
  phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.


ensembl_gene_id: NAP1_05210
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: NAP1_05270
symbol: parE
gene_biotype: protein_coding
description:
  Topoisomerase B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: NAP1_05280
symbol: rsmI
gene_biotype: protein_coding
description:
  Predicted methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: NAP1_05285
symbol: EAQ30163.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: NAP1_05290
symbol: gshB
gene_biotype: protein_coding
description:
  COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: NAP1_05300
symbol: EAQ30166.1
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: NAP1_05305
symbol: EAQ30167.1
gene_biotype: protein_coding
description:
  Putative deoxyribonucleotide triphosphate pyrophosphatase; COG2340 Uncharacterized protein with SCP/PR1 domains.


ensembl_gene_id: NAP1_05310
symbol: EAQ30168.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: NAP1_05315
symbol: rph
gene_biotype: protein_coding
description:
  RNase PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: NAP1_05320
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: NAP1_05325
symbol: grpE
gene_biotype: protein_coding
description:
  Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]


ensembl_gene_id: NAP1_05330
symbol: EAQ30172.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: NAP1_05365
symbol: dnaJ
gene_biotype: protein_coding
description:
  DnaJ molecular chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]


ensembl_gene_id: NAP1_05385
symbol: radA
gene_biotype: protein_coding
description:
  Predicted ATP-dependent serine protease; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: NAP1_05405
symbol: EAQ30187.1
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: NAP1_05415
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: NAP1_05425
symbol: rnr
gene_biotype: protein_coding
description:
  Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: NAP1_05440
symbol: EAQ30194.1
gene_biotype: protein_coding
description:
  COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: NAP1_05485
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: NAP1_05495
symbol: metG
gene_biotype: protein_coding
description:
  methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.


ensembl_gene_id: NAP1_05520
symbol: hflX
gene_biotype: protein_coding
description:
  GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: NAP1_05525
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: NAP1_05535
symbol: EAQ30213.1
gene_biotype: protein_coding
description:
  COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation.


ensembl_gene_id: NAP1_05540
symbol: EAQ30214.1
gene_biotype: protein_coding
description:
  NtrC, nitrogen regulation protein NtrC; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.


ensembl_gene_id: NAP1_05550
symbol: EAQ30216.1
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: NAP1_05555
symbol: ispDF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).


ensembl_gene_id: NAP1_05565
symbol: EAQ30219.1
gene_biotype: protein_coding
description:
  Possible competence-damaged protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: NAP1_05575
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: NAP1_05590
symbol: EAQ30224.1
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: NAP1_05605
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: NAP1_05620
symbol: trmFO
gene_biotype: protein_coding
description:
  Glucose-inhibited division protein A; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.


ensembl_gene_id: NAP1_05650
symbol: EAQ30236.1
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: NAP1_05655
symbol: pdhA
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: NAP1_05675
symbol: EAQ30241.1
gene_biotype: protein_coding
description:
  Haloalkane dehalogenase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: NAP1_05715
symbol: EAQ30249.1
gene_biotype: protein_coding
description:
  Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: NAP1_05720
symbol: EAQ30250.1
gene_biotype: protein_coding
description:
  Heat shock protein; COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: NAP1_05725
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: NAP1_05730
symbol: EAQ30252.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: NAP1_05735
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: NAP1_05745
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: NAP1_05755
symbol: EAQ30257.1
gene_biotype: protein_coding
description:
  Putative proline iminopeptidase protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the peptidase S33 family.


ensembl_gene_id: NAP1_05765
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: NAP1_05775
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: NAP1_05780
symbol: EAQ30262.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: NAP1_05785
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: NAP1_05795
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.


ensembl_gene_id: NAP1_05840
symbol: coaX
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: NAP1_05850
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: NAP1_05860
symbol: EAQ30278.1
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: NAP1_05865
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH dehydrogenase kappa subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: NAP1_05870
symbol: EAQ30280.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: NAP1_05875
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: NAP1_05880
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: NAP1_05885
symbol: EAQ30283.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase gamma subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: NAP1_05895
symbol: EAQ30285.1
gene_biotype: protein_coding
description:
  NADH-ubiquinone dehydrogenase chain F 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: NAP1_05910
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase delta subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: NAP1_05915
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: NAP1_05925
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH dehydrogenase-ubiquinone oxidoreductase, chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: NAP1_05930
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH Dehydrogenase I Chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: NAP1_05955
symbol: EAQ30297.1
gene_biotype: protein_coding
description:
  COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: NAP1_05970
symbol: EAQ30300.1
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: NAP1_05975
symbol: EAQ30301.1
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-ACP dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: NAP1_05985
symbol: prfB
gene_biotype: protein_coding
description:
  Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: NAP1_06010
symbol: rne
gene_biotype: protein_coding
description:
  Ribonuclease; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: NAP1_06030
symbol: EAQ30312.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_06035
symbol: EAQ30313.1
gene_biotype: protein_coding
description:
  COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: NAP1_06040
symbol: EAQ30314.1
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: NAP1_06055
symbol: EAQ30317.1
gene_biotype: protein_coding
description:
  Amidotransferase class-II; Similar to asparagine synthase (glutamine-hydrolyzing); COG0367 Asparagine synthase (glutamine-hydrolyzing).


ensembl_gene_id: NAP1_06080
symbol: EAQ30322.1
gene_biotype: protein_coding
description:
  General secretion pathway protein-related protein; COG3267 Type II secretory pathway, component ExeA (predicted ATPase).


ensembl_gene_id: NAP1_06090
symbol: EAQ30324.1
gene_biotype: protein_coding
description:
  Probable exopolysaccharide biosynthesis protein; COG0489 ATPases involved in chromosome partitioning.


ensembl_gene_id: NAP1_06130
symbol: EAQ30332.1
gene_biotype: protein_coding
description:
  Esterase/lipase/thioesterase family active site protein; COG2945 Predicted hydrolase of the alpha/beta superfamily.


ensembl_gene_id: NAP1_06135
symbol: EAQ30333.1
gene_biotype: protein_coding
description:
  COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: NAP1_06145
symbol: nnrD
gene_biotype: protein_coding
description:
  Sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of  [...]


ensembl_gene_id: NAP1_06165
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: NAP1_06185
symbol: EAQ30343.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: NAP1_06260
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.


ensembl_gene_id: NAP1_06270
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: NAP1_06275
symbol: EAQ30361.1
gene_biotype: protein_coding
description:
  Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_06295
symbol: EAQ30365.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.


ensembl_gene_id: NAP1_06310
symbol: EAQ30368.1
gene_biotype: protein_coding
description:
  Hydrolase, NUDIX family, NudH subfamily protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family.


ensembl_gene_id: NAP1_06325
symbol: EAQ30371.1
gene_biotype: protein_coding
description:
  COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: NAP1_06335
symbol: guaB
gene_biotype: protein_coding
description:
  IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: NAP1_06345
symbol: EAQ30375.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_06360
symbol: EAQ30378.1
gene_biotype: protein_coding
description:
  Ankyrin-related protein; COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component.


ensembl_gene_id: NAP1_06390
symbol: EAQ30384.1
gene_biotype: protein_coding
description:
  COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: NAP1_06405
symbol: EAQ30387.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_06450
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: NAP1_06465
symbol: bamD
gene_biotype: protein_coding
description:
  DNA uptake lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: NAP1_06480
symbol: EAQ30402.1
gene_biotype: protein_coding
description:
  Cold-shock dead-box protein A; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: NAP1_06485
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: NAP1_06505
symbol: EAQ30407.1
gene_biotype: protein_coding
description:
  Poly(3-hydroxyalkanoate) depolymerase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: NAP1_06540
symbol: EAQ30414.1
gene_biotype: protein_coding
description:
  DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: NAP1_06550
symbol: EAQ30416.1
gene_biotype: protein_coding
description:
  Dehydrogenase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_06585
symbol: EAQ30423.1
gene_biotype: protein_coding
description:
  Putative ABC transport system membrane protein; COG2354 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: NAP1_06595
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: NAP1_06605
symbol: amn
gene_biotype: protein_coding
description:
  AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: NAP1_06625
symbol: rimK
gene_biotype: protein_coding
description:
  S6 modification enzyme RimK; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the RimK family.


ensembl_gene_id: NAP1_06665
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: NAP1_06670
symbol: EAQ30440.1
gene_biotype: protein_coding
description:
  Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: NAP1_06680
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: NAP1_06685
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA-(guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: NAP1_06720
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: NAP1_06730
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual component [...]


ensembl_gene_id: NAP1_06740
symbol: aroA
gene_biotype: protein_coding
description:
  5-enolpyruvylshikimate-3-phosphate synthase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: NAP1_06760
symbol: EAQ30458.1
gene_biotype: protein_coding
description:
  30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: NAP1_06765
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: NAP1_06770
symbol: EAQ30460.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase, zinc-containing; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: NAP1_06775
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: NAP1_06780
symbol: atpF-2
gene_biotype: protein_coding
description:
  ATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: NAP1_06785
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase subunit A; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: NAP1_06790
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: NAP1_06795
symbol: EAQ30465.1
gene_biotype: protein_coding
description:
  Hypothetical protein; A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.


ensembl_gene_id: NAP1_06835
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: NAP1_06850
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: NAP1_06860
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: NAP1_06865
symbol: accD
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: NAP1_06870
symbol: EAQ30480.1
gene_biotype: protein_coding
description:
  Putative folylpolyglutamate/dihydrofolate synthase; COG0285 Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: NAP1_06880
symbol: EAQ30482.1
gene_biotype: protein_coding
description:
  Putative ferredoxin subunits of nitrite reductase andring-hydroxylating dioxygenase; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: NAP1_06885
symbol: EAQ30483.1
gene_biotype: protein_coding
description:
  S4 domain protein; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: NAP1_06970
symbol: EAQ30500.1
gene_biotype: protein_coding
description:
  COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: NAP1_06980
symbol: EAQ30502.1
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: NAP1_06990
symbol: alaS
gene_biotype: protein_coding
description:
  AlaS, alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: NAP1_06995
symbol: recA
gene_biotype: protein_coding
description:
  Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: NAP1_07010
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: NAP1_07020
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: NAP1_07030
symbol: EAQ30512.1
gene_biotype: protein_coding
description:
  Transglycosylase; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: NAP1_07035
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: NAP1_07045
symbol: EAQ30515.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: NAP1_07050
symbol: rlmN
gene_biotype: protein_coding
description:
  Predicted Fe-S-cluster redox enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: NAP1_07075
symbol: EAQ30521.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_07080
symbol: EAQ30522.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein).


ensembl_gene_id: NAP1_07105
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: NAP1_07110
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: NAP1_07150
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: NAP1_07180
symbol: EAQ30542.1
gene_biotype: protein_coding
description:
  Ferrichrome ABC transporter ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: NAP1_07185
symbol: EAQ30543.1
gene_biotype: protein_coding
description:
  ABC cobalamin/Fe3+-siderophore transporter, inner membrane subunit; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: NAP1_07205
symbol: EAQ30547.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: NAP1_07210
symbol: mdh
gene_biotype: protein_coding
description:
  Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.


ensembl_gene_id: NAP1_07220
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: NAP1_07230
symbol: EAQ30552.1
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: NAP1_07260
symbol: EAQ30558.1
gene_biotype: protein_coding
description:
  Beta-lactamase family protein; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: NAP1_07300
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: NAP1_07305
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: NAP1_07310
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: NAP1_07330
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: NAP1_07335
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: NAP1_07340
symbol: rplO
gene_biotype: protein_coding
description:
  Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: NAP1_07350
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: NAP1_07355
symbol: rplR
gene_biotype: protein_coding
description:
  Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: NAP1_07360
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: NAP1_07365
symbol: rpsH
gene_biotype: protein_coding
description:
  Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: NAP1_07370
symbol: rpsN
gene_biotype: protein_coding
description:
  Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: NAP1_07375
symbol: rplE
gene_biotype: protein_coding
description:
  Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: NAP1_07380
symbol: rplX
gene_biotype: protein_coding
description:
  Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: NAP1_07390
symbol: rplN
gene_biotype: protein_coding
description:
  Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: NAP1_07395
symbol: rpsQ
gene_biotype: protein_coding
description:
  Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: NAP1_07405
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: NAP1_07410
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: NAP1_07415
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: NAP1_07420
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: NAP1_07425
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: NAP1_07430
symbol: rplW
gene_biotype: protein_coding
description:
  Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: NAP1_07440
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: NAP1_07450
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein s10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: NAP1_07455
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: NAP1_07460
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 sub [...]


ensembl_gene_id: NAP1_07470
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: NAP1_07475
symbol: rpsL
gene_biotype: protein_coding
description:
  Ribosomal protein S12, bacterial and chloroplast form; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: NAP1_07490
symbol: EAQ30604.1
gene_biotype: protein_coding
description:
  Peptidase S1 and S6, chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: NAP1_07520
symbol: EAQ30610.1
gene_biotype: protein_coding
description:
  Putative formyltransferase protein; COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN.


ensembl_gene_id: NAP1_07535
symbol: metZ
gene_biotype: protein_coding
description:
  Cystathionine beta-lyase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.


ensembl_gene_id: NAP1_07555
symbol: EAQ30617.1
gene_biotype: protein_coding
description:
  Putative dolichol monophosphate mannose synthase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: NAP1_07560
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: NAP1_07635
symbol: EAQ30633.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: NAP1_07645
symbol: azoR
gene_biotype: protein_coding
description:
  Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: NAP1_07655
symbol: nadE
gene_biotype: protein_coding
description:
  NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: NAP1_07705
symbol: EAQ30647.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.


ensembl_gene_id: NAP1_07745
symbol: EAQ30655.1
gene_biotype: protein_coding
description:
  Putative acyltransferase transmembrane protein; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase.


ensembl_gene_id: NAP1_07760
symbol: ybeY
gene_biotype: protein_coding
description:
  Predicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: NAP1_07800
symbol: miaB
gene_biotype: protein_coding
description:
  2-methylthioadenine synthetase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: NAP1_07810
symbol: EAQ30668.1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: NAP1_07850
symbol: EAQ30676.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_07855
symbol: EAQ30677.1
gene_biotype: protein_coding
description:
  Hypothetical 2-hydroxychromene-2-carboxylateisomerase family protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: NAP1_07860
symbol: EAQ30678.1
gene_biotype: protein_coding
description:
  NUDIX hydrolase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding; Belongs to the Nudix hydrolase family.


ensembl_gene_id: NAP1_07905
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor alpha-subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: NAP1_07910
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: NAP1_07915
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: NAP1_07925
symbol: EAQ30691.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3788 Uncharacterized relative of glutathione S-transferase, MAPEG superfamily.


ensembl_gene_id: NAP1_07935
symbol: EAQ30693.1
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, ArsR family protein; COG0640 Predicted transcriptional regulators.


ensembl_gene_id: NAP1_07970
symbol: EAQ30700.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: NAP1_07975
symbol: EAQ30701.1
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: NAP1_08000
symbol: EAQ30706.1
gene_biotype: protein_coding
description:
  COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase).


ensembl_gene_id: NAP1_08005
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.


ensembl_gene_id: NAP1_08015
symbol: EAQ30709.1
gene_biotype: protein_coding
description:
  Beta-lactamase (penicillin-binding protein) (penicillinase); COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: NAP1_08025
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: NAP1_08045
symbol: EAQ30715.1
gene_biotype: protein_coding
description:
  Putative 3-oxoacyl-[ACP] reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_08080
symbol: EAQ30722.1
gene_biotype: protein_coding
description:
  Putative protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: NAP1_08100
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase subunit D; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: NAP1_08105
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: NAP1_08110
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: NAP1_08120
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: NAP1_08130
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: NAP1_08175
symbol: glmU
gene_biotype: protein_coding
description:
  N-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: NAP1_08185
symbol: EAQ30743.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_08220
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: NAP1_08230
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: NAP1_08302
symbol: pepA
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: NAP1_08307
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family.


ensembl_gene_id: NAP1_08317
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: NAP1_08322
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: NAP1_08332
symbol: glcB
gene_biotype: protein_coding
description:
  Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.


ensembl_gene_id: NAP1_08337
symbol: EAQ27586.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: NAP1_08347
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: NAP1_08367
symbol: mscL
gene_biotype: protein_coding
description:
  Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: NAP1_08417
symbol: recF
gene_biotype: protein_coding
description:
  Recombinational DNA repair ATPase; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: NAP1_08427
symbol: EAQ27604.1
gene_biotype: protein_coding
description:
  ABC efflux transporter, ATPase subunit; COG4181 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component.


ensembl_gene_id: NAP1_08432
symbol: EAQ27605.1
gene_biotype: protein_coding
description:
  ABC transporter, permease protein; COG3127 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component.


ensembl_gene_id: NAP1_08467
symbol: EAQ27612.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_08472
symbol: EAQ27613.1
gene_biotype: protein_coding
description:
  Proline/sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: NAP1_08537
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: NAP1_08557
symbol: EAQ27630.1
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein; COG4233 Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis.


ensembl_gene_id: NAP1_08572
symbol: EAQ27633.1
gene_biotype: protein_coding
description:
  uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: NAP1_08577
symbol: EAQ27634.1
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.


ensembl_gene_id: NAP1_08582
symbol: tsaD
gene_biotype: protein_coding
description:
  Metal-dependent protease; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: NAP1_08587
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: NAP1_08597
symbol: EAQ27638.1
gene_biotype: protein_coding
description:
  Putative secreted protein; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.


ensembl_gene_id: NAP1_08622
symbol: EAQ27643.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: NAP1_08657
symbol: EAQ27650.1
gene_biotype: protein_coding
description:
  Adenylate/guanylate cyclase catalytic domain protein; COG4252 Predicted transmembrane sensor domain.


ensembl_gene_id: NAP1_08677
symbol: EAQ27654.1
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: NAP1_08682
symbol: EAQ27655.1
gene_biotype: protein_coding
description:
  Metallo-beta-lactamase family protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.


ensembl_gene_id: NAP1_08722
symbol: EAQ27663.1
gene_biotype: protein_coding
description:
  Putative transcription regulator protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: NAP1_08757
symbol: EAQ27670.1
gene_biotype: protein_coding
description:
  Secretion protein HlyD; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: NAP1_08777
symbol: EAQ27674.1
gene_biotype: protein_coding
description:
  Glutathione S-transferase, N-terminal:Glutathione S-transferase, C-terminal; COG0625 Glutathione S-transferase.


ensembl_gene_id: NAP1_08782
symbol: EAQ27675.1
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase-like, FMN-binding; COG3576 Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase.


ensembl_gene_id: NAP1_08797
symbol: EAQ27678.1
gene_biotype: protein_coding
description:
  ABC sugar (glycerol) transporter, periplasmic binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: NAP1_08807
symbol: EAQ27680.1
gene_biotype: protein_coding
description:
  ABC sugar (glycerol) transporter, inner membrane subunit; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: NAP1_08812
symbol: EAQ27681.1
gene_biotype: protein_coding
description:
  ABC sugar (glycerol) transporter, inner membrane subunit; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: NAP1_08817
symbol: EAQ27682.1
gene_biotype: protein_coding
description:
  COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: NAP1_08887
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: NAP1_08892
symbol: rpsO
gene_biotype: protein_coding
description:
  Ribosomal protein S15P; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: NAP1_08897
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: NAP1_08902
symbol: EAQ27699.1
gene_biotype: protein_coding
description:
  Putative sodium/myo-inositol cotransporter; COG4146 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: NAP1_08912
symbol: EAQ27701.1
gene_biotype: protein_coding
description:
  COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: NAP1_08947
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: NAP1_08967
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: NAP1_08977
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: NAP1_08982
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: NAP1_08992
symbol: EAQ27717.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: NAP1_09012
symbol: EAQ27721.1
gene_biotype: protein_coding
description:
  COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain.


ensembl_gene_id: NAP1_09097
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: NAP1_09112
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: NAP1_09127
symbol: EAQ27744.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0271 Stress-induced morphogen (activity unknown); Belongs to the BolA/IbaG family.


ensembl_gene_id: NAP1_09147
symbol: EAQ27748.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: NAP1_09157
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: NAP1_09162
symbol: EAQ27751.1
gene_biotype: protein_coding
description:
  Type IV secretion system protein B11, putative; Part of the Type IV secretion system. Belongs to the GSP E family.


ensembl_gene_id: NAP1_09167
symbol: EAQ27752.1
gene_biotype: protein_coding
description:
  Type IV secretion system protein B10, putative; COG2948 Type IV secretory pathway, VirB10 components.


ensembl_gene_id: NAP1_09197
symbol: EAQ27758.1
gene_biotype: protein_coding
description:
  Transglycosylase SLT domain protein; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: NAP1_09217
symbol: EAQ27762.1
gene_biotype: protein_coding
description:
  Two-component phosphate transcriptional regulator PhoB; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: NAP1_09227
symbol: EAQ27764.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_09252
symbol: EAQ27769.1
gene_biotype: protein_coding
description:
  Iron binding protein component of ABC iron transporter; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: NAP1_09257
symbol: EAQ27770.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components.


ensembl_gene_id: NAP1_09262
symbol: EAQ27771.1
gene_biotype: protein_coding
description:
  iron(III) ABC transporter permease protein; COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: NAP1_09267
symbol: EAQ27772.1
gene_biotype: protein_coding
description:
  Putative Mg chelatase subunit Bchl; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.


ensembl_gene_id: NAP1_09307
symbol: EAQ27780.1
gene_biotype: protein_coding
description:
  Bacteriochlorophyllide reductase subunit BchX; COG1348 Nitrogenase subunit NifH (ATPase); Belongs to the NifH/BchL/ChlL family.


ensembl_gene_id: NAP1_09312
symbol: EAQ27781.1
gene_biotype: protein_coding
description:
  Bacteriochlorophyllide reductase subunit BchY; COG2710 Nitrogenase molybdenum-iron protein, alpha and beta chains.


ensembl_gene_id: NAP1_09317
symbol: EAQ27782.1
gene_biotype: protein_coding
description:
  Bacteriochlorophyllide reductase subunit; COG2710 Nitrogenase molybdenum-iron protein, alpha and beta chains.


ensembl_gene_id: NAP1_09322
symbol: EAQ27783.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.


ensembl_gene_id: NAP1_09332
symbol: EAQ27785.1
gene_biotype: protein_coding
description:
  Photosynthetic reaction center L subunit; COG0477 Permeases of the major facilitator superfamily; Belongs to the reaction center PufL/M/PsbA/D family.


ensembl_gene_id: NAP1_09337
symbol: EAQ27786.1
gene_biotype: protein_coding
description:
  Photosynthetic reaction center M protein; The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis.


ensembl_gene_id: NAP1_09362
symbol: EAQ27791.1
gene_biotype: protein_coding
description:
  Possible Bch2, light harvesting pigment Major Facilitator Family(MFS) transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: NAP1_09367
symbol: EAQ27792.1
gene_biotype: protein_coding
description:
  Putative bacteriochlorophyll synthase, 34 kDa subunit; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases.


ensembl_gene_id: NAP1_09377
symbol: EAQ27794.1
gene_biotype: protein_coding
description:
  Coenzyme B12-binding protein; COG2185 Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).


ensembl_gene_id: NAP1_09382
symbol: EAQ27795.1
gene_biotype: protein_coding
description:
  Possible 2-vinyl bacteriochlorophillide hydratase BchF; COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component.


ensembl_gene_id: NAP1_09387
symbol: bchN
gene_biotype: protein_coding
description:
  Light-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.


ensembl_gene_id: NAP1_09392
symbol: bchB
gene_biotype: protein_coding
description:
  Protochlorophyllide reductase BchB subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.


ensembl_gene_id: NAP1_09397
symbol: EAQ27798.1
gene_biotype: protein_coding
description:
  Magnesium-protoporphyrin O-methyltransferase BchH subunit; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.


ensembl_gene_id: NAP1_09402
symbol: bchL
gene_biotype: protein_coding
description:
  Protochlorophyllide reductase iron-sulfur ATP-binding protein BchL; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.


ensembl_gene_id: NAP1_09407
symbol: EAQ27800.1
gene_biotype: protein_coding
description:
  Mg-protoporphyrin IX methyl transferase; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase.


ensembl_gene_id: NAP1_09417
symbol: EAQ27802.1
gene_biotype: protein_coding
description:
  H subunit of photosynthetic reaction center complex; COG3861 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: NAP1_09437
symbol: acsF
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family.


ensembl_gene_id: NAP1_09472
symbol: EAQ27813.1
gene_biotype: protein_coding
description:
  Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamidedehydrogenase (E3) component and related enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: NAP1_09487
symbol: EAQ27816.1
gene_biotype: protein_coding
description:
  Toxin secretion ABC transporter ATP-binding protein; COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: NAP1_09502
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: NAP1_09522
symbol: EAQ27823.1
gene_biotype: protein_coding
description:
  Aldehyde oxidase; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: NAP1_09527
symbol: EAQ27824.1
gene_biotype: protein_coding
description:
  Isoquinoline 1-oxidoreductase, alpha subunit; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


ensembl_gene_id: NAP1_09572
symbol: EAQ27833.1
gene_biotype: protein_coding
description:
  Cytochrome c family protein; COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain.


ensembl_gene_id: NAP1_09577
symbol: cpdA
gene_biotype: protein_coding
description:
  Putative cAMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: NAP1_09722
symbol: EAQ27863.1
gene_biotype: protein_coding
description:
  Putative sodium/hexose cotransport protein; COG4146 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: NAP1_09852
symbol: EAQ27889.1
gene_biotype: protein_coding
description:
  Guanosine polyphosphate pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: NAP1_09872
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor 3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: NAP1_09937
symbol: pal
gene_biotype: protein_coding
description:
  Probable peptidoglycan-associated lipoprotein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: NAP1_09942
symbol: tolB
gene_biotype: protein_coding
description:
  Translocation protein TolB precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: NAP1_09967
symbol: EAQ27912.1
gene_biotype: protein_coding
description:
  Hypothetical HIT-like protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: NAP1_09977
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazoleglycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: NAP1_09987
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: NAP1_10017
symbol: EAQ27922.1
gene_biotype: protein_coding
description:
  Putative beta-ketoacyl reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_10073
symbol: dapD
gene_biotype: protein_coding
description:
  COG2171 Tetrahydrodipicolinate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: NAP1_10193
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: NAP1_10288
symbol: EAQ27975.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: NAP1_10318
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: NAP1_10333
symbol: EAQ27984.1
gene_biotype: protein_coding
description:
  Possible Dps protein family starvation-inducible DNA-binding protein; COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family.


ensembl_gene_id: NAP1_10348
symbol: EAQ27987.1
gene_biotype: protein_coding
description:
  4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconatealdolase (eda); COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: NAP1_10393
symbol: EAQ27996.1
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: NAP1_10398
symbol: EAQ27997.1
gene_biotype: protein_coding
description:
  COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family.


ensembl_gene_id: NAP1_10408
symbol: EAQ27999.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: NAP1_10418
symbol: EAQ28001.1
gene_biotype: protein_coding
description:
  Glycine dehydrogenase subunit 2; COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain.


ensembl_gene_id: NAP1_10423
symbol: gcvPA
gene_biotype: protein_coding
description:
  Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.


ensembl_gene_id: NAP1_10428
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: NAP1_10468
symbol: EAQ28011.1
gene_biotype: protein_coding
description:
  Putative curlin production assembly/transport component csgg precursor; COG1462 Uncharacterized protein involved in formation of curli polymers.


ensembl_gene_id: NAP1_10478
symbol: EAQ28013.1
gene_biotype: protein_coding
description:
  5-methyltetrahydrofolate-homocysteine methyltransferase; COG1410 Methionine synthase I, cobalamin-binding domain.


ensembl_gene_id: NAP1_10488
symbol: EAQ28015.1
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: NAP1_10528
symbol: EAQ28023.1
gene_biotype: protein_coding
description:
  Transcriptional regulator lysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: NAP1_10548
symbol: EAQ28027.1
gene_biotype: protein_coding
description:
  Transcriptional regulator araC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: NAP1_10553
symbol: EAQ28028.1
gene_biotype: protein_coding
description:
  Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.


ensembl_gene_id: NAP1_10558
symbol: EAQ28029.1
gene_biotype: protein_coding
description:
  Putative hypoxanthine-guanine phosphoribosyltransferase; COG2236 Predicted phosphoribosyltransferases.


ensembl_gene_id: NAP1_10603
symbol: EAQ28038.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma-70 factor, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: NAP1_10693
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: NAP1_10753
symbol: EAQ28068.1
gene_biotype: protein_coding
description:
  COG1301 Na+/H+-dicarboxylate symporters; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: NAP1_10758
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: NAP1_10778
symbol: rlmE
gene_biotype: protein_coding
description:
  23S rRNA methylase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: NAP1_10808
symbol: EAQ28079.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: NAP1_10843
symbol: EAQ28086.1
gene_biotype: protein_coding
description:
  Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_10888
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: NAP1_10898
symbol: EAQ28097.1
gene_biotype: protein_coding
description:
  Putative protein disulfide isomerase; COG1331 Highly conserved protein containing a thioredoxin domain.


ensembl_gene_id: NAP1_10903
symbol: mntP
gene_biotype: protein_coding
description:
  Hypothetical protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: NAP1_10908
symbol: EAQ28099.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein.


ensembl_gene_id: NAP1_10958
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction resolvasome helicase subunit; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: NAP1_10968
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase motor protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: NAP1_10973
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: NAP1_11013
symbol: EAQ28120.1
gene_biotype: protein_coding
description:
  Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: NAP1_11023
symbol: katG
gene_biotype: protein_coding
description:
  Catalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: NAP1_11063
symbol: secB
gene_biotype: protein_coding
description:
  Preprotein translocase subunit; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: NAP1_11068
symbol: murJ
gene_biotype: protein_coding
description:
  Putative virulence factor mvin-like transmembrane protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: NAP1_11073
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: NAP1_11088
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: NAP1_11103
symbol: EAQ28138.1
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.


ensembl_gene_id: NAP1_11108
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: NAP1_11113
symbol: mutM
gene_biotype: protein_coding
description:
  formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: NAP1_11123
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: NAP1_11128
symbol: EAQ28143.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: NAP1_11143
symbol: EAQ28146.1
gene_biotype: protein_coding
description:
  Class II aldolase/adducin domain protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: NAP1_11148
symbol: cobB
gene_biotype: protein_coding
description:
  COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: NAP1_11153
symbol: EAQ28148.1
gene_biotype: protein_coding
description:
  Putative membrane-located cell surface saccharide saccharideacetylase protein; COG1835 Predicted acyltransferases.


ensembl_gene_id: NAP1_11158
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: NAP1_11168
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: NAP1_11183
symbol: dapE
gene_biotype: protein_coding
description:
  Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: NAP1_11188
symbol: EAQ28155.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: NAP1_11218
symbol: engB
gene_biotype: protein_coding
description:
  GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: NAP1_11223
symbol: yidC
gene_biotype: protein_coding
description:
  Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: NAP1_11228
symbol: EAQ28163.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: NAP1_11233
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: NAP1_11318
symbol: EAQ28181.1
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: NAP1_11333
symbol: EAQ28184.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: NAP1_11338
symbol: EAQ28185.1
gene_biotype: protein_coding
description:
  Phospholipase D/Transphosphatidylase; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: NAP1_11343
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: NAP1_11358
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent Zn protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: NAP1_11368
symbol: EAQ28191.1
gene_biotype: protein_coding
description:
  ABC-transporter permease protein, putative; COG0577 ABC-type antimicrobial peptide transport system, permease component.


ensembl_gene_id: NAP1_11373
symbol: EAQ28192.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: NAP1_11418
symbol: EAQ28201.1
gene_biotype: protein_coding
description:
  Glycosyltransferase-like (PssD) protein; COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase.


ensembl_gene_id: NAP1_11428
symbol: EAQ28203.1
gene_biotype: protein_coding
description:
  UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: NAP1_11433
symbol: EAQ28204.1
gene_biotype: protein_coding
description:
  COG0381 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.


ensembl_gene_id: NAP1_11453
symbol: EAQ28208.1
gene_biotype: protein_coding
description:
  Glycosyl transferase, group 2 family protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.


ensembl_gene_id: NAP1_11463
symbol: EAQ28210.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family).


ensembl_gene_id: NAP1_11483
symbol: EAQ28214.1
gene_biotype: protein_coding
description:
  Hypothetical polysaccharide biosynthesis related protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: NAP1_11538
symbol: EAQ28225.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: NAP1_11563
symbol: EAQ28230.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.


ensembl_gene_id: NAP1_11588
symbol: EAQ28235.1
gene_biotype: protein_coding
description:
  Putative NADH dehydrogenase (ubiquinone) 1 alpha subcomplex; COG0702 Predicted nucleoside-diphosphate-sugar epimerases.


ensembl_gene_id: NAP1_11603
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: NAP1_11618
symbol: purT
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: NAP1_11638
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: NAP1_11648
symbol: EAQ28247.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family.


ensembl_gene_id: NAP1_11658
symbol: ruvC
gene_biotype: protein_coding
description:
  Holliday junction resolvasome endonuclease subunit; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: NAP1_11723
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase 160 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: NAP1_11728
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: NAP1_11753
symbol: rplJ
gene_biotype: protein_coding
description:
  Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: NAP1_11758
symbol: rplL
gene_biotype: protein_coding
description:
  50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: NAP1_11773
symbol: groES
gene_biotype: protein_coding
description:
  Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: NAP1_11778
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: NAP1_11808
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: NAP1_11838
symbol: EAQ28285.1
gene_biotype: protein_coding
description:
  COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: NAP1_11848
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: NAP1_11853
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: NAP1_11863
symbol: prmC
gene_biotype: protein_coding
description:
  Protein chain release factors methylase subunit; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: NAP1_11868
symbol: prfA
gene_biotype: protein_coding
description:
  Protein chain release factor A; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: NAP1_11878
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: NAP1_11903
symbol: EAQ28298.1
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit N; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: NAP1_11918
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: NAP1_11938
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: NAP1_11958
symbol: EAQ28309.1
gene_biotype: protein_coding
description:
  ATP:cob(I)alamin adenosyltransferase, putative; Belongs to the Cob(I)alamin adenosyltransferase family.


ensembl_gene_id: NAP1_11968
symbol: EAQ28311.1
gene_biotype: protein_coding
description:
  COG0008 Glutamyl- and glutaminyl-tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: NAP1_11988
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: NAP1_11993
symbol: kynB
gene_biotype: protein_coding
description:
  Putative cyclase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation.


ensembl_gene_id: NAP1_11998
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: NAP1_12008
symbol: EAQ28319.1
gene_biotype: protein_coding
description:
  Putative oligopeptide uptake ABC transporter periplasmic solute-binding protein precursor; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: NAP1_12023
symbol: dksA
gene_biotype: protein_coding
description:
  DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.


ensembl_gene_id: NAP1_12078
symbol: EAQ28333.1
gene_biotype: protein_coding
description:
  MIP family protein; COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: NAP1_12183
symbol: queC
gene_biotype: protein_coding
description:
  ExsB; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: NAP1_12193
symbol: EAQ28356.1
gene_biotype: protein_coding
description:
  Chaperone protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.


ensembl_gene_id: NAP1_12198
symbol: EAQ28357.1
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: NAP1_12203
symbol: argD
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: NAP1_12253
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: NAP1_12258
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase beta subunit; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: NAP1_12263
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: NAP1_12278
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: NAP1_12313
symbol: prs
gene_biotype: protein_coding
description:
  Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: NAP1_12328
symbol: EAQ28383.1
gene_biotype: protein_coding
description:
  glpX protein; COG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins.


ensembl_gene_id: NAP1_12353
symbol: EAQ28388.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: NAP1_12403
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: NAP1_12413
symbol: EAQ28400.1
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: NAP1_12418
symbol: cysC
gene_biotype: protein_coding
description:
  Sulfate adenylate transferase, subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: NAP1_12423
symbol: EAQ28402.1
gene_biotype: protein_coding
description:
  Putative inositol monophosphatase; COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase.


ensembl_gene_id: NAP1_12428
symbol: EAQ28403.1
gene_biotype: protein_coding
description:
  Photosystem I P700 chlorophyll A apoprotein A2; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: NAP1_12438
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: NAP1_12448
symbol: EAQ28407.1
gene_biotype: protein_coding
description:
  PetB, ubiquinol-cytochrome c reductase, cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: NAP1_12453
symbol: EAQ28408.1
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome-c reductase; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: NAP1_12508
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: NAP1_12513
symbol: purE
gene_biotype: protein_coding
description:
  Probable phosphoribosylaminoimidazole carboxylase catalytic subunit protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: NAP1_12518
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: NAP1_12523
symbol: EAQ28422.1
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: NAP1_12538
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: NAP1_12543
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: NAP1_12563
symbol: EAQ28430.1
gene_biotype: protein_coding
description:
  Putative myo-inositol monophosphatase 2 family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: NAP1_12568
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: NAP1_12598
symbol: EAQ28437.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: NAP1_12603
symbol: EAQ28438.1
gene_biotype: protein_coding
description:
  HlyD family secretion protein; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: NAP1_12623
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: NAP1_12643
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: NAP1_12673
symbol: EAQ28452.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein CapD type; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: NAP1_12718
symbol: EAQ28461.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: NAP1_12763
symbol: coq7
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis.


ensembl_gene_id: NAP1_12783
symbol: rlmH
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: NAP1_12788
symbol: rsfS
gene_biotype: protein_coding
description:
  Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: NAP1_12793
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinic acid mononucleotide adenyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: NAP1_12798
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: NAP1_12848
symbol: EAQ28487.1
gene_biotype: protein_coding
description:
  ATPase; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: NAP1_12853
symbol: EAQ28488.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing.


ensembl_gene_id: NAP1_12898
symbol: EAQ28497.1
gene_biotype: protein_coding
description:
  COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog).


ensembl_gene_id: NAP1_12903
symbol: EAQ28498.1
gene_biotype: protein_coding
description:
  Ferredoxin II; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: NAP1_12928
symbol: EAQ28503.1
gene_biotype: protein_coding
description:
  Putative translation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.


ensembl_gene_id: NAP1_12973
symbol: EAQ28512.1
gene_biotype: protein_coding
description:
  Chromosome partitioning protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: NAP1_12983
symbol: rsmG
gene_biotype: protein_coding
description:
  Glucose inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: NAP1_12988
symbol: mnmG
gene_biotype: protein_coding
description:
  Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: NAP1_12993
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: NAP1_13013
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: NAP1_13023
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: NAP1_13028
symbol: EAQ28523.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: NAP1_13033
symbol: EAQ28524.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: NAP1_13038
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: NAP1_13043
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: NAP1_13048
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: NAP1_13053
symbol: hpf
gene_biotype: protein_coding
description:
  Ribosome-associated protein Y; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: NAP1_13058
symbol: EAQ28529.1
gene_biotype: protein_coding
description:
  PtsN, PTS system, nitrogen regulatory IIA component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).


ensembl_gene_id: NAP1_13123
symbol: fumC
gene_biotype: protein_coding
description:
  Probable fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: NAP1_13133
symbol: EAQ28544.1
gene_biotype: protein_coding
description:
  Putative response regulator in two-component regulatory system; COG3279 Response regulator of the LytR/AlgR family.


ensembl_gene_id: NAP1_13168
symbol: rplM
gene_biotype: protein_coding
description:
  Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: NAP1_13183
symbol: ctaA
gene_biotype: protein_coding
description:
  Cytochrome c oxidase assembly protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 2 subfamily.


ensembl_gene_id: NAP1_13193
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: NAP1_13213
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: NAP1_13253
symbol: EAQ28568.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.


ensembl_gene_id: NAP1_13263
symbol: EAQ28570.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: NAP1_13268
symbol: EAQ28571.1
gene_biotype: protein_coding
description:
  Selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: NAP1_13318
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: NAP1_13348
symbol: tadA
gene_biotype: protein_coding
description:
  Cytidine/deoxycytidylate deaminase, zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: NAP1_13373
symbol: EAQ28592.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: NAP1_13388
symbol: EAQ28595.1
gene_biotype: protein_coding
description:
  Two-component signal transduction histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.


ensembl_gene_id: NAP1_13458
symbol: EAQ28609.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase.


ensembl_gene_id: NAP1_13483
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: NAP1_13498
symbol: msrA
gene_biotype: protein_coding
description:
  Possible peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: NAP1_13508
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: NAP1_13573
symbol: EAQ28632.1
gene_biotype: protein_coding
description:
  Integration host factor beta-subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: NAP1_13578
symbol: EAQ28633.1
gene_biotype: protein_coding
description:
  COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: NAP1_13628
symbol: EAQ28643.1
gene_biotype: protein_coding
description:
  5-methylcytosine-specific restriction enzyme A; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase.


ensembl_gene_id: NAP1_13633
symbol: EAQ28644.1
gene_biotype: protein_coding
description:
  DNA mismatch endonuclease Vsr, putative; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: NAP1_13643
symbol: EAQ28646.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4973 Site-specific recombinase XerC; Belongs to the 'phage' integrase family.


ensembl_gene_id: NAP1_13668
symbol: EAQ28651.1
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase.


ensembl_gene_id: NAP1_13683
symbol: EAQ28654.1
gene_biotype: protein_coding
description:
  ABC transporter, ATP-binding protein; COG4152 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: NAP1_13688
symbol: queG
gene_biotype: protein_coding
description:
  Iron-sulfur cluster-binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: NAP1_13698
symbol: EAQ28657.1
gene_biotype: protein_coding
description:
  Putative ferredoxin reductase component (dioxygenase); COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: NAP1_13708
symbol: EAQ28659.1
gene_biotype: protein_coding
description:
  Flavin dependant oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: NAP1_13763
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: NAP1_13793
symbol: EAQ28676.1
gene_biotype: protein_coding
description:
  Putative glutamate-ammonia-ligase adenylyltransferase protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds  [...]


ensembl_gene_id: NAP1_13838
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: NAP1_13848
symbol: EAQ28687.1
gene_biotype: protein_coding
description:
  COG4321 Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis.


ensembl_gene_id: NAP1_13873
symbol: EAQ28692.1
gene_biotype: protein_coding
description:
  acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: NAP1_13923
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: NAP1_13938
symbol: EAQ28705.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: NAP1_13943
symbol: EAQ28706.1
gene_biotype: protein_coding
description:
  Glutamate synthase, NADH/NADPH small subunit; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: NAP1_13983
symbol: EAQ28714.1
gene_biotype: protein_coding
description:
  Putative 3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: NAP1_14003
symbol: EAQ28718.1
gene_biotype: protein_coding
description:
  Similar to protein up-regulated by thyroid hormone-putative PQQ-dependent glucose dehydrogenase; COG2133 Glucose/sorbosone dehydrogenases.


ensembl_gene_id: NAP1_14028
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: NAP1_14103
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: NAP1_14118
symbol: EAQ28741.1
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein-sorting protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: NAP1_14203
symbol: EAQ28758.1
gene_biotype: protein_coding
description:
  Phosphate binding protein, putative; COG0226 ABC-type phosphate transport system, periplasmic component.


ensembl_gene_id: NAP1_14228
symbol: EAQ28763.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: NAP1_14243
symbol: glnD
gene_biotype: protein_coding
description:
  PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: NAP1_14253
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglycerol transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: NAP1_14273
symbol: EAQ28772.1
gene_biotype: protein_coding
description:
  ABC transporter permease protein; COG1174 ABC-type proline/glycine betaine transport systems, permease component.


ensembl_gene_id: NAP1_14283
symbol: EAQ28774.1
gene_biotype: protein_coding
description:
  ABC transporter, ATPase subunit; COG1125 ABC-type proline/glycine betaine transport systems, ATPase components.


ensembl_gene_id: NAP1_14313
symbol: EAQ28780.1
gene_biotype: protein_coding
description:
  propionyl-CoA carboxylase, beta subunit, putative; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).


ensembl_gene_id: NAP1_14343
symbol: gyrB
gene_biotype: protein_coding
description:
  Type IIA topoisomerase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: NAP1_14358
symbol: EAQ28789.1
gene_biotype: protein_coding
description:
  4-coumarate-CoA ligase, putative; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: NAP1_14488
symbol: EAQ28815.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: NAP1_14518
symbol: EAQ28821.1
gene_biotype: protein_coding
description:
  Ribonucleotide reductase beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: NAP1_14593
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: NAP1_14603
symbol: folD
gene_biotype: protein_coding
description:
  Probable tetrahydrofolate dehydrogenase/cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: NAP1_14628
symbol: EAQ28843.1
gene_biotype: protein_coding
description:
  ATP-dependent proteinase; COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease.


ensembl_gene_id: NAP1_14683
symbol: EAQ28854.1
gene_biotype: protein_coding
description:
  PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: NAP1_14708
symbol: mtnP
gene_biotype: protein_coding
description:
  5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.


ensembl_gene_id: NAP1_14723
symbol: EAQ28862.1
gene_biotype: protein_coding
description:
  Tyrosine protein kinase:Aminoglycoside phosphotransferase; COG3173 Predicted aminoglycoside phosphotransferase.


ensembl_gene_id: NAP1_14743
symbol: EAQ28866.1
gene_biotype: protein_coding
description:
  COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: NAP1_14788
symbol: EAQ28875.1
gene_biotype: protein_coding
description:
  Flagellar proximal rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: NAP1_14818
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: NAP1_14823
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: NAP1_14863
symbol: EAQ28890.1
gene_biotype: protein_coding
description:
  Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: NAP1_14878
symbol: EAQ28893.1
gene_biotype: protein_coding
description:
  Flagellar M-Ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: NAP1_14903
symbol: EAQ28898.1
gene_biotype: protein_coding
description:
  Putative nicotinate-nucleotide- dimethylbenzimidazolephosphoribosyltransferase; COG0810 Periplasmic protein TonB, links inner and outer membranes.


ensembl_gene_id: NAP1_14908
symbol: EAQ28899.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: NAP1_14913
symbol: EAQ28900.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1107 Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain.


ensembl_gene_id: NAP1_14918
symbol: EAQ28901.1
gene_biotype: protein_coding
description:
  Flagellar motor switch protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: NAP1_14928
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar transport protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: NAP1_14933
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: NAP1_14948
symbol: EAQ28907.1
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: NAP1_14958
symbol: EAQ28909.1
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase fold:Esterase/lipase/thioesterase, active site protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: NAP1_14963
symbol: nhaA-2
gene_biotype: protein_coding
description:
  Na+/H+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: NAP1_14968
symbol: EAQ28911.1
gene_biotype: protein_coding
description:
  Nitrilotriacetate monooxygenase component B; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: NAP1_14993
symbol: EAQ28916.1
gene_biotype: protein_coding
description:
  COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: NAP1_15008
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: NAP1_15033
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: NAP1_15038
symbol: metXA
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: NAP1_15063
symbol: msrB
gene_biotype: protein_coding
description:
  Methionine sulfoxide reductase B; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: NAP1_15073
symbol: EAQ28932.1
gene_biotype: protein_coding
description:
  COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.


ensembl_gene_id: NAP1_15083
symbol: EAQ28934.1
gene_biotype: protein_coding
description:
  Probable integral membrane proteinase; COG0330 Membrane protease subunits, stomatin/prohibitin homologs.


ensembl_gene_id: NAP1_15088
symbol: EAQ28935.1
gene_biotype: protein_coding
description:
  ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: NAP1_15093
symbol: EAQ28936.1
gene_biotype: protein_coding
description:
  Probable transmembrane isoquinoline 1-oxidoreductase (beta subunit) oxidoreductase protein; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: NAP1_15098
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: NAP1_15133
symbol: msrA-2
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: NAP1_15158
symbol: EAQ28949.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: NAP1_15168
symbol: EAQ28951.1
gene_biotype: protein_coding
description:
  Twin-arginine translocation pathway signal; COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.


ensembl_gene_id: NAP1_15193
symbol: EAQ28956.1
gene_biotype: protein_coding
description:
  Oxidoreductase iron/ascorbate family protein; COG3491 Isopenicillin N synthase and related dioxygenases; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: NAP1_15198
symbol: EAQ28957.1
gene_biotype: protein_coding
description:
  Putative outer membrane protein with a TonB box; COG4771 Outer membrane receptor for ferrienterochelin and colicins.


ensembl_gene_id: NAP1_15203
symbol: EAQ28958.1
gene_biotype: protein_coding
description:
  Sensor histidine kinase with multiple PAS/PAC and a response regulator receiver domain; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: NAP1_15268
symbol: aat
gene_biotype: protein_coding
description:
  leu/phe-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: NAP1_15283
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: NAP1_15288
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antiterminator; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: NAP1_15293
symbol: EAQ28976.1
gene_biotype: protein_coding
description:
  Transcriptional regulator (LysR family protein); COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: NAP1_15298
symbol: EAQ28977.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: NAP1_15318
symbol: EAQ28981.1
gene_biotype: protein_coding
description:
  Putative integral membrane protein; COG1299 Phosphotransferase system, fructose-specific IIC component.


ensembl_gene_id: NAP1_15323
symbol: rplK
gene_biotype: protein_coding
description:
  Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: NAP1_15328
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: NAP1_15358
symbol: EAQ28989.1
gene_biotype: protein_coding
description:
  Monooxygenase, flavin-binding family protein; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: NAP1_15418
symbol: EAQ29001.1
gene_biotype: protein_coding
description:
  Conserved secreted Zn-dependent enzyme fromdeacylase/carboxypeptidase superfamily protein; COG2866 Predicted carboxypeptidase.


ensembl_gene_id: NAP1_15438
symbol: EAQ29005.1
gene_biotype: protein_coding
description:
  Capsular polysaccharide biosynthesis protein; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.


ensembl_gene_id: NAP1_15468
symbol: EAQ29011.1
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase.


ensembl_gene_id: NAP1_15473
symbol: EAQ29012.1
gene_biotype: protein_coding
description:
  CBS domain:Sugar isomerase (SIS):KpsF/GutQ family protein; COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Belongs to the SIS family. GutQ/KpsF subfamily.


ensembl_gene_id: NAP1_15478
symbol: kdsA
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphooctonate aldolase; COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Belongs to the KdsA family.


ensembl_gene_id: NAP1_15528
symbol: EAQ29023.1
gene_biotype: protein_coding
description:
  Capsule polysaccharide export ATP-binding protein; COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component.


ensembl_gene_id: NAP1_15533
symbol: EAQ29024.1
gene_biotype: protein_coding
description:
  Capsule polysaccharide export inner-membrane protein; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: NAP1_15548
symbol: EAQ29027.1
gene_biotype: protein_coding
description:
  Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: NAP1_15553
symbol: EAQ29028.1
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: NAP1_15558
symbol: EAQ29029.1
gene_biotype: protein_coding
description:
  dTDP-6-deoxy-L-mannose-dehydrogenase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: NAP1_15563
symbol: EAQ29030.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: NAP1_15568
symbol: EAQ29031.1
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: NAP1_15578
symbol: EAQ29033.1
gene_biotype: protein_coding
description:
  Phosphomannose isomerase / guanosine 5'-diphospho-D-mannosepyrophosphorylase; COG0836 Mannose-1-phosphate guanylyltransferase.


ensembl_gene_id: NAP1_15598
symbol: EAQ29037.1
gene_biotype: protein_coding
description:
  Acetyltransferase, putative; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: NAP1_15618
symbol: EAQ29041.1
gene_biotype: protein_coding
description:
  ompA family protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: NAP1_15658
symbol: EAQ29049.1
gene_biotype: protein_coding
description:
  Electron transport protein; COG1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems.


ensembl_gene_id: NAP1_15673
symbol: EAQ29052.1
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: NAP1_15683
symbol: EAQ29054.1
gene_biotype: protein_coding
description:
  Predicted transcription regulator, containing DNA-binding HTH domain; COG1476 Predicted transcriptional regulators.


ensembl_gene_id: NAP1_15708
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: NAP1_15718
symbol: EAQ29061.1
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.


ensembl_gene_id: NAP1_15733
symbol: EAQ29064.1
gene_biotype: protein_coding
description:
  COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components.


ensembl_gene_id: NAP1_15743
symbol: EAQ29066.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.


ensembl_gene_id: NAP1_15748
symbol: EAQ29067.1
gene_biotype: protein_coding
description:
  CBS domain protein; COG2905 Predicted signal-transduction protein containing cAMP-binding and CBS domains.


ensembl_gene_id: NAP1_15763
symbol: EAQ29070.1
gene_biotype: protein_coding
description:
  Sodium:solute symporter family protein; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: NAP1_15773
symbol: EAQ29072.1
gene_biotype: protein_coding
description:
  Putative regulator in two-component regulatory system; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: NAP1_15778
symbol: acsA-2
gene_biotype: protein_coding
description:
  Probable acetyl-coenzyme a synthetase protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: NAP1_15798
symbol: EAQ29077.1
gene_biotype: protein_coding
description:
  COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: NAP1_15803
symbol: EAQ29078.1
gene_biotype: protein_coding
description:
  COG3278 Cbb3-type cytochrome oxidase, subunit 1; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: NAP1_15838
symbol: EAQ29085.1
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase; COG3197 Uncharacterized protein, possibly involved in nitrogen fixation.


ensembl_gene_id: NAP1_15848
symbol: EAQ29087.1
gene_biotype: protein_coding
description:
  COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: NAP1_15868
symbol: EAQ29091.1
gene_biotype: protein_coding
description:
  Chemotaxis-specific methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: NAP1_15903
symbol: EAQ29098.1
gene_biotype: protein_coding
description:
  Probable isoquinoline 1-oxidoreductase (alpha subunit)oxidoreductase protein; COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs.


