# geneInfo

ensembl_gene_id: VAB18032_00005
symbol: AEB47085.1
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: VAB18032_00020
symbol: AEB47088.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: VAB18032_00030
symbol: whiB
gene_biotype: protein_coding
description:
  Transcription factor whib; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: VAB18032_00040
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: VAB18032_00045
symbol: rsgA
gene_biotype: protein_coding
description:
  Gtpase engc; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: VAB18032_00050
symbol: AEB47094.1
gene_biotype: protein_coding
description:
  COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: VAB18032_00065
symbol: AEB47097.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase sdr; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: VAB18032_00075
symbol: AEB47099.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, luxr family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_00090
symbol: purC
gene_biotype: protein_coding
description:
  COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family.


ensembl_gene_id: VAB18032_00190
symbol: AEB47122.1
gene_biotype: protein_coding
description:
  Nudix hydrolase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.


ensembl_gene_id: VAB18032_00215
symbol: AEB47127.1
gene_biotype: protein_coding
description:
  UvrD/REP helicase; COG0210 Superfamily I DNA and RNA helicases; Belongs to the helicase family. UvrD subfamily.


ensembl_gene_id: VAB18032_00225
symbol: AEB47129.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1611 Predicted Rossmann fold nucleotide-binding protein; Belongs to the LOG family.


ensembl_gene_id: VAB18032_00245
symbol: dapD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.


ensembl_gene_id: VAB18032_00250
symbol: AEB47134.1
gene_biotype: protein_coding
description:
  Peptidase s8 and s53 subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: VAB18032_00285
symbol: AEB47141.1
gene_biotype: protein_coding
description:
  4fe-4S ferredoxin iron-sulfur binding domain-containing protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.


ensembl_gene_id: VAB18032_00290
symbol: AEB47142.1
gene_biotype: protein_coding
description:
  Gcn5-related n-acetyltransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: VAB18032_00305
symbol: mshB
gene_biotype: protein_coding
description:
  1d-myo-inosityl-2-acetamido-2-deoxy-alpha-d- glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.


ensembl_gene_id: VAB18032_00310
symbol: AEB47146.1
gene_biotype: protein_coding
description:
  Peptidase s9b dipeptidylpeptidase iv domain protein; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases.


ensembl_gene_id: VAB18032_00315
symbol: AEB47147.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 5; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: VAB18032_00330
symbol: AEB47150.1
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATPase subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_00335
symbol: AEB47151.1
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter ATPase subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_00340
symbol: AEB47152.1
gene_biotype: protein_coding
description:
  Peptidase U62 modulator of DNA gyrase; COG0312 Predicted Zn-dependent proteases and their inactivated homologs.


ensembl_gene_id: VAB18032_00395
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: VAB18032_00415
symbol: AEB47167.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_00420
symbol: AEB47168.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_00425
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner.


ensembl_gene_id: VAB18032_00465
symbol: AEB47177.1
gene_biotype: protein_coding
description:
  COG0538 Isocitrate dehydrogenases; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: VAB18032_00485
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: VAB18032_00490
symbol: AEB47182.1
gene_biotype: protein_coding
description:
  Family 5 extracellular solute-binding protein; COG4166 ABC-type oligopeptide transport system, periplasmic component.


ensembl_gene_id: VAB18032_00505
symbol: AEB47185.1
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_00510
symbol: AEB47186.1
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide abc transporter, atpase subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_00515
symbol: purH
gene_biotype: protein_coding
description:
  Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).


ensembl_gene_id: VAB18032_00520
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: VAB18032_00560
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: VAB18032_00565
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: VAB18032_00585
symbol: AEB47201.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: VAB18032_00600
symbol: AEB47204.1
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide ABC transporter, ATPase subunit; COG4608 ABC-type oligopeptide transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_00625
symbol: AEB47209.1
gene_biotype: protein_coding
description:
  Regulatory protein LuxR; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_00650
symbol: AEB47214.1
gene_biotype: protein_coding
description:
  Cdp-alcohol phosphatidyltransferase; COG1183 Phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: VAB18032_00655
symbol: AEB47215.1
gene_biotype: protein_coding
description:
  NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: VAB18032_00660
symbol: AEB47216.1
gene_biotype: protein_coding
description:
  Nudix hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.


ensembl_gene_id: VAB18032_00680
symbol: AEB47220.1
gene_biotype: protein_coding
description:
  LytR/CpsA family cell envelope-related function transcriptional attenuator; COG1316 Transcriptional regulator.


ensembl_gene_id: VAB18032_00695
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: VAB18032_00715
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin groel; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: VAB18032_00720
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: VAB18032_00745
symbol: AEB47233.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4214 ABC-type xylose transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: VAB18032_00770
symbol: AEB47238.1
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: VAB18032_00785
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: VAB18032_00795
symbol: AEB47243.1
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: VAB18032_00800
symbol: nnrD
gene_biotype: protein_coding
description:
  Carbohydrate kinase, yjef related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.


ensembl_gene_id: VAB18032_00815
symbol: glmS
gene_biotype: protein_coding
description:
  Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: VAB18032_00825
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: VAB18032_00835
symbol: rplM
gene_biotype: protein_coding
description:
  50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: VAB18032_00855
symbol: AEB47255.1
gene_biotype: protein_coding
description:
  Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: VAB18032_00865
symbol: AEB47257.1
gene_biotype: protein_coding
description:
  Nitrite reductase (NAD(P)H) large subunit; COG1251 NAD(P)H-nitrite reductase; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: VAB18032_00875
symbol: AEB47259.1
gene_biotype: protein_coding
description:
  Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein; COG1587 Uroporphyrinogen-III synthase.


ensembl_gene_id: VAB18032_00900
symbol: AEB47264.1
gene_biotype: protein_coding
description:
  Extracellular ligand-binding receptor; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: VAB18032_00905
symbol: AEB47265.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: VAB18032_00910
symbol: AEB47266.1
gene_biotype: protein_coding
description:
  Membrane lipoprotein lipid attachment site; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: VAB18032_00915
symbol: AEB47267.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: VAB18032_00920
symbol: AEB47268.1
gene_biotype: protein_coding
description:
  COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_00935
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.


ensembl_gene_id: VAB18032_00950
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: VAB18032_00965
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: VAB18032_01005
symbol: truA
gene_biotype: protein_coding
description:
  tRNA-pseudouridine synthase i; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: VAB18032_01015
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: VAB18032_01020
symbol: rpsD
gene_biotype: protein_coding
description:
  30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: VAB18032_01025
symbol: rpsK
gene_biotype: protein_coding
description:
  30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: VAB18032_01030
symbol: rpsM
gene_biotype: protein_coding
description:
  30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: VAB18032_01040
symbol: infA
gene_biotype: protein_coding
description:
  Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: VAB18032_01050
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: VAB18032_01055
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: VAB18032_01060
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: VAB18032_01065
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: VAB18032_01075
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: VAB18032_01080
symbol: rplR
gene_biotype: protein_coding
description:
  50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: VAB18032_01085
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: VAB18032_01090
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: VAB18032_01095
symbol: rpsZ
gene_biotype: protein_coding
description:
  Ribosomal protein s14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.


ensembl_gene_id: VAB18032_01100
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: VAB18032_01105
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: VAB18032_01110
symbol: rplN
gene_biotype: protein_coding
description:
  50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: VAB18032_01115
symbol: rpsQ
gene_biotype: protein_coding
description:
  30S ribosomal protein s17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: VAB18032_01125
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: VAB18032_01130
symbol: rpsC
gene_biotype: protein_coding
description:
  Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: VAB18032_01135
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: VAB18032_01140
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: VAB18032_01145
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: VAB18032_01150
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: VAB18032_01160
symbol: rplC
gene_biotype: protein_coding
description:
  50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: VAB18032_01165
symbol: rpsJ
gene_biotype: protein_coding
description:
  30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: VAB18032_01170
symbol: tuf
gene_biotype: protein_coding
description:
  Translation elongation factor tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: VAB18032_01175
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: VAB18032_01180
symbol: rpsG
gene_biotype: protein_coding
description:
  30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: VAB18032_01185
symbol: rpsL
gene_biotype: protein_coding
description:
  30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: VAB18032_01200
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: VAB18032_01210
symbol: rplL
gene_biotype: protein_coding
description:
  Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: VAB18032_01215
symbol: rplJ
gene_biotype: protein_coding
description:
  50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: VAB18032_01220
symbol: rplA
gene_biotype: protein_coding
description:
  50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: VAB18032_01225
symbol: rplK
gene_biotype: protein_coding
description:
  50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: VAB18032_01230
symbol: nusG
gene_biotype: protein_coding
description:
  Nusg antitermination factor; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: VAB18032_01235
symbol: secE
gene_biotype: protein_coding
description:
  Preprotein translocase, sece subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.


ensembl_gene_id: VAB18032_01255
symbol: AEB47335.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with gaf sensor; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: VAB18032_01280
symbol: AEB47340.1
gene_biotype: protein_coding
description:
  Putative nucleotide-binding protein; COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family.


ensembl_gene_id: VAB18032_01295
symbol: pyrE-2
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: VAB18032_01310
symbol: htpX
gene_biotype: protein_coding
description:
  Peptidase M48 Ste24p; COG0501 Zn-dependent protease with chaperone function; Belongs to the peptidase M48B family.


ensembl_gene_id: VAB18032_01315
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH/Ubiquinone/plastoquinone (complex I); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: VAB18032_01320
symbol: AEB47348.1
gene_biotype: protein_coding
description:
  Proton-translocating NADH-quinone oxidoreductase, chain M; COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M).


ensembl_gene_id: VAB18032_01325
symbol: AEB47349.1
gene_biotype: protein_coding
description:
  Proton-translocating NADH-quinone oxidoreductase, chain l; COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: VAB18032_01330
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-ubiquinone oxidoreductase chain 4L; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: VAB18032_01335
symbol: AEB47351.1
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 6; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: VAB18032_01340
symbol: nuoI
gene_biotype: protein_coding
description:
  4fe-4S ferredoxin iron-sulfur binding domain-containing protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: VAB18032_01355
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: VAB18032_01360
symbol: AEB47356.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase (ubiquinone) 30 kda subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: VAB18032_01365
symbol: AEB47357.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase groes domain protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: VAB18032_01375
symbol: nuoB
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: VAB18032_01390
symbol: AEB47362.1
gene_biotype: protein_coding
description:
  methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding protein; COG3695 Predicted methylated DNA-protein cysteine methyltransferase.


ensembl_gene_id: VAB18032_01395
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: VAB18032_01400
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: VAB18032_01410
symbol: AEB47366.1
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis-like protein MoeZ; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: VAB18032_01450
symbol: AEB47374.1
gene_biotype: protein_coding
description:
  Dead/deah box helicase domain protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: VAB18032_01485
symbol: AEB47381.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_01490
symbol: AEB47382.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: VAB18032_01495
symbol: AEB47383.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: VAB18032_01500
symbol: AEB47384.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: VAB18032_01505
symbol: AEB47385.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: VAB18032_01545
symbol: AEB47393.1
gene_biotype: protein_coding
description:
  Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.


ensembl_gene_id: VAB18032_01575
symbol: AEB47399.1
gene_biotype: protein_coding
description:
  Glycoprotease family protein; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.


ensembl_gene_id: VAB18032_01590
symbol: AEB47402.1
gene_biotype: protein_coding
description:
  Sua5/ycio/yrdc/ywlc family protein; COG0009 Putative translation factor (SUA5); Belongs to the SUA5 family.


ensembl_gene_id: VAB18032_01595
symbol: tsaD
gene_biotype: protein_coding
description:
  UGMP family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: VAB18032_01605
symbol: AEB47405.1
gene_biotype: protein_coding
description:
  Putative ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: VAB18032_01765
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: VAB18032_01770
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: VAB18032_01775
symbol: rex
gene_biotype: protein_coding
description:
  Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.


ensembl_gene_id: VAB18032_01790
symbol: AEB47442.1
gene_biotype: protein_coding
description:
  COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: VAB18032_01830
symbol: AEB47450.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: VAB18032_01835
symbol: AEB47451.1
gene_biotype: protein_coding
description:
  Efflux transporter RND family, MFP subunit; COG0845 Membrane-fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: VAB18032_01885
symbol: AEB47461.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: VAB18032_01900
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase 1 family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: VAB18032_01930
symbol: mshA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.


ensembl_gene_id: VAB18032_01935
symbol: AEB47471.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity.


ensembl_gene_id: VAB18032_01955
symbol: AEB47475.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_01965
symbol: AEB47477.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: VAB18032_02010
symbol: AEB47486.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_02020
symbol: AEB47488.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase sdr; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_02030
symbol: AEB47490.1
gene_biotype: protein_coding
description:
  Threonyl/alanyl tRNA synthetase SAD; COG2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain.


ensembl_gene_id: VAB18032_02065
symbol: AEB47497.1
gene_biotype: protein_coding
description:
  Folate-binding protein YgfZ; COG0354 Predicted aminomethyltransferase related to GcvT; Belongs to the GcvT family.


ensembl_gene_id: VAB18032_02070
symbol: AEB47498.1
gene_biotype: protein_coding
description:
  Ferric uptake regulator family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: VAB18032_02075
symbol: AEB47499.1
gene_biotype: protein_coding
description:
  Aminotransferase class IV; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: VAB18032_02110
symbol: AEB47506.1
gene_biotype: protein_coding
description:
  COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: VAB18032_02150
symbol: AEB47514.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: VAB18032_02160
symbol: mshD
gene_biotype: protein_coding
description:
  Mycothiol biosynthesis acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.


ensembl_gene_id: VAB18032_02200
symbol: AEB47524.1
gene_biotype: protein_coding
description:
  Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter; Belongs to the GroES chaperonin family.


ensembl_gene_id: VAB18032_02240
symbol: AEB47532.1
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; COG0578 Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: VAB18032_02265
symbol: groEL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: VAB18032_02315
symbol: AEB47547.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.


ensembl_gene_id: VAB18032_02330
symbol: AEB47550.1
gene_biotype: protein_coding
description:
  Histidine kinase HAMP region domain-containing protein; COG0642 Signal transduction histidine kinase.


ensembl_gene_id: VAB18032_02335
symbol: AEB47551.1
gene_biotype: protein_coding
description:
  Roadblock/lc7 family protein; COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid.


ensembl_gene_id: VAB18032_02385
symbol: AEB47561.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, deor family protein; COG1349 Transcriptional regulators of sugar metabolism.


ensembl_gene_id: VAB18032_02390
symbol: AEB47562.1
gene_biotype: protein_coding
description:
  Sugar isomerase (SIS); COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains.


ensembl_gene_id: VAB18032_02420
symbol: AEB47568.1
gene_biotype: protein_coding
description:
  TrkA domain-containing protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: VAB18032_02440
symbol: AEB47572.1
gene_biotype: protein_coding
description:
  COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: VAB18032_02445
symbol: AEB47573.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_02450
symbol: AEB47574.1
gene_biotype: protein_coding
description:
  RNA methyltransferase, trmh family, group 3; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: VAB18032_02500
symbol: AEB47584.1
gene_biotype: protein_coding
description:
  Helix-turn-helix domain-containing protein; COG1813 Predicted transcription factor, homolog of eukaryotic MBF1.


ensembl_gene_id: VAB18032_02510
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: VAB18032_02525
symbol: AEB47589.1
gene_biotype: protein_coding
description:
  Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: VAB18032_02565
symbol: pat
gene_biotype: protein_coding
description:
  Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: VAB18032_02580
symbol: AEB47600.1
gene_biotype: protein_coding
description:
  Fumarylacetoacetase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: VAB18032_02600
symbol: ispF
gene_biotype: protein_coding
description:
  2c-methyl-d-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: VAB18032_02605
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: VAB18032_02610
symbol: AEB47606.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, card family protein; COG1329 Transcriptional regulators, similar to M. xanthus CarD.


ensembl_gene_id: VAB18032_02625
symbol: AEB47609.1
gene_biotype: protein_coding
description:
  Chalcone and stilbene synthase domain-containing protein; COG3424 Predicted naringenin-chalcone synthase.


ensembl_gene_id: VAB18032_02635
symbol: AEB47611.1
gene_biotype: protein_coding
description:
  Methyltransferase type 11; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase.


ensembl_gene_id: VAB18032_02650
symbol: radA
gene_biotype: protein_coding
description:
  DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: VAB18032_02655
symbol: disA
gene_biotype: protein_coding
description:
  DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.


ensembl_gene_id: VAB18032_02665
symbol: def-2
gene_biotype: protein_coding
description:
  Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: VAB18032_02685
symbol: AEB47621.1
gene_biotype: protein_coding
description:
  Atpase aaa-2 domain protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: VAB18032_02700
symbol: coaX
gene_biotype: protein_coding
description:
  Transcriptional acitvator, baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.


ensembl_gene_id: VAB18032_02720
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: VAB18032_02725
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: VAB18032_02740
symbol: nuoD
gene_biotype: protein_coding
description:
  NADH dehydrogenase (quinone); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: VAB18032_02750
symbol: AEB47634.1
gene_biotype: protein_coding
description:
  COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein).


ensembl_gene_id: VAB18032_02780
symbol: AEB47640.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: VAB18032_02790
symbol: AEB47642.1
gene_biotype: protein_coding
description:
  2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.


ensembl_gene_id: VAB18032_02795
symbol: AEB47643.1
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: VAB18032_02800
symbol: AEB47644.1
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: VAB18032_02860
symbol: ftsH
gene_biotype: protein_coding
description:
  ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: VAB18032_02865
symbol: AEB47657.1
gene_biotype: protein_coding
description:
  COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: VAB18032_02875
symbol: AEB47659.1
gene_biotype: protein_coding
description:
  ThiJ/PfpI domain-containing protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: VAB18032_02880
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: VAB18032_02895
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: VAB18032_02915
symbol: AEB47667.1
gene_biotype: protein_coding
description:
  Phosphoesterase, PA-phosphatase related protein; COG0671 Membrane-associated phospholipid phosphatase.


ensembl_gene_id: VAB18032_02920
symbol: AEB47668.1
gene_biotype: protein_coding
description:
  Peptidase S1 and S6 chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: VAB18032_02935
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: VAB18032_02940
symbol: AEB47672.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation).


ensembl_gene_id: VAB18032_02950
symbol: AEB47674.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, crp/fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: VAB18032_02980
symbol: AEB47680.1
gene_biotype: protein_coding
description:
  Tap domain protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: VAB18032_03040
symbol: whiB-4
gene_biotype: protein_coding
description:
  Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.


ensembl_gene_id: VAB18032_03045
symbol: AEB47693.1
gene_biotype: protein_coding
description:
  Glycosyl transferase family protein; COG0744 Membrane carboxypeptidase (penicillin-binding protein).


ensembl_gene_id: VAB18032_03090
symbol: AEB47702.1
gene_biotype: protein_coding
description:
  LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_03110
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: VAB18032_03115
symbol: trpA-2
gene_biotype: protein_coding
description:
  Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: VAB18032_03155
symbol: cpdA
gene_biotype: protein_coding
description:
  Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: VAB18032_03165
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: VAB18032_03185
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.


ensembl_gene_id: VAB18032_03190
symbol: AEB47722.1
gene_biotype: protein_coding
description:
  EmrB/QacA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: VAB18032_03225
symbol: AEB47729.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: VAB18032_03230
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: VAB18032_03235
symbol: AEB47731.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: VAB18032_03270
symbol: AEB47738.1
gene_biotype: protein_coding
description:
  COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: VAB18032_03280
symbol: AEB47740.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: VAB18032_03285
symbol: AEB47741.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: VAB18032_03355
symbol: tadA
gene_biotype: protein_coding
description:
  CMP/dCMP deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: VAB18032_03485
symbol: AEB47781.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.


ensembl_gene_id: VAB18032_03655
symbol: AEB47813.1
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase gCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: VAB18032_03675
symbol: AEB47817.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: VAB18032_03690
symbol: AEB47820.1
gene_biotype: protein_coding
description:
  Two component LuxR family transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_03725
symbol: AEB47827.1
gene_biotype: protein_coding
description:
  Globin; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; Belongs to the globin family.


ensembl_gene_id: VAB18032_03730
symbol: def-3
gene_biotype: protein_coding
description:
  XRE family transcriptional regulator; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: VAB18032_03845
symbol: AEB47851.1
gene_biotype: protein_coding
description:
  Nad(p)h quinone oxidoreductase, pig3 family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: VAB18032_03900
symbol: AEB47862.1
gene_biotype: protein_coding
description:
  Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: VAB18032_03910
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein cora; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: VAB18032_03915
symbol: AEB47865.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, gntr family protein; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: VAB18032_03935
symbol: AEB47869.1
gene_biotype: protein_coding
description:
  Nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon).


ensembl_gene_id: VAB18032_03945
symbol: AEB47871.1
gene_biotype: protein_coding
description:
  Cdp-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: VAB18032_03965
symbol: AEB47875.1
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate galactose phosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.


ensembl_gene_id: VAB18032_03975
symbol: AEB47877.1
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, lyttr family protein; COG3279 Response regulator of the LytR/AlgR family.


ensembl_gene_id: VAB18032_04005
symbol: AEB47883.1
gene_biotype: protein_coding
description:
  COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: VAB18032_04015
symbol: AEB47885.1
gene_biotype: protein_coding
description:
  Sss sodium solute transporter superfamily protein; COG4147 Predicted symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: VAB18032_04100
symbol: AEB47902.1
gene_biotype: protein_coding
description:
  Peroxiredoxin, osmc subfamily protein; COG1764 Predicted redox protein, regulator of disulfide bond formation.


ensembl_gene_id: VAB18032_04145
symbol: AEB47911.1
gene_biotype: protein_coding
description:
  COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats.


ensembl_gene_id: VAB18032_04165
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: VAB18032_04185
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein a; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: VAB18032_04250
symbol: AEB47932.1
gene_biotype: protein_coding
description:
  MoeA domain-containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: VAB18032_04260
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein c; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: VAB18032_04270
symbol: AEB47936.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: VAB18032_04290
symbol: AEB47940.1
gene_biotype: protein_coding
description:
  Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: VAB18032_04305
symbol: rpsR
gene_biotype: protein_coding
description:
  30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: VAB18032_04360
symbol: AEB47954.1
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: VAB18032_04370
symbol: AEB47956.1
gene_biotype: protein_coding
description:
  Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: VAB18032_04385
symbol: AEB47959.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: VAB18032_04415
symbol: AEB47965.1
gene_biotype: protein_coding
description:
  COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: VAB18032_04420
symbol: ddl
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: VAB18032_04430
symbol: AEB47968.1
gene_biotype: protein_coding
description:
  parB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.


ensembl_gene_id: VAB18032_04440
symbol: gidB
gene_biotype: protein_coding
description:
  16S rRNA methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.


ensembl_gene_id: VAB18032_04445
symbol: AEB47971.1
gene_biotype: protein_coding
description:
  Single-stranded nucleic acid binding R3H domain-containing protein; COG1847 Predicted RNA-binding protein.


ensembl_gene_id: VAB18032_04455
symbol: AEB47973.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: VAB18032_04460
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: VAB18032_04470
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: VAB18032_04475
symbol: AEB47977.1
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: VAB18032_04485
symbol: recF
gene_biotype: protein_coding
description:
  Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: VAB18032_04490
symbol: AEB47980.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG5512 Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives.


ensembl_gene_id: VAB18032_04500
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: VAB18032_04505
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: VAB18032_04610
symbol: AEB42048.1
gene_biotype: protein_coding
description:
  Thiol-specific antioxidant related protein/peroxidoxin BcpB; COG0789 Predicted transcriptional regulators.


ensembl_gene_id: VAB18032_04640
symbol: AEB42054.1
gene_biotype: protein_coding
description:
  DSBA oxidoreductase; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: VAB18032_04655
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: VAB18032_04790
symbol: AEB42084.1
gene_biotype: protein_coding
description:
  Peptidase S8/S53 subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: VAB18032_04795
symbol: AEB42085.1
gene_biotype: protein_coding
description:
  WecB/TagA/CpsF family glycosyl transferase; COG1922 Teichoic acid biosynthesis proteins; Belongs to the glycosyltransferase 26 family.


ensembl_gene_id: VAB18032_04830
symbol: AEB42092.1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase-like domain-containing protein; COG0515 Serine/threonine protein kinase.


ensembl_gene_id: VAB18032_04885
symbol: dcd
gene_biotype: protein_coding
description:
  Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.


ensembl_gene_id: VAB18032_04935
symbol: AEB42113.1
gene_biotype: protein_coding
description:
  Luciferase family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_04960
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein a; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: VAB18032_05005
symbol: pxpA
gene_biotype: protein_coding
description:
  Lamb/ycsf family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: VAB18032_05010
symbol: AEB42128.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase/ thiol specific antioxidant/ mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins.


ensembl_gene_id: VAB18032_05030
symbol: AEB42132.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: VAB18032_05035
symbol: AEB42133.1
gene_biotype: protein_coding
description:
  Transketolase, central region; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: VAB18032_05040
symbol: AEB42134.1
gene_biotype: protein_coding
description:
  COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: VAB18032_05080
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: VAB18032_05085
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: VAB18032_05110
symbol: clpB
gene_biotype: protein_coding
description:
  ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: VAB18032_05130
symbol: AEB42152.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG0300 Short-chain dehydrogenases of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: VAB18032_05170
symbol: AEB42160.1
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: VAB18032_05195
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: VAB18032_05285
symbol: purA-2
gene_biotype: protein_coding
description:
  Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: VAB18032_05310
symbol: fabG
gene_biotype: protein_coding
description:
  3-ketoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_05340
symbol: purS
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...]


ensembl_gene_id: VAB18032_05345
symbol: purQ
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase i; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]


ensembl_gene_id: VAB18032_05350
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist  [...]


ensembl_gene_id: VAB18032_05370
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.


ensembl_gene_id: VAB18032_05375
symbol: purM
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine cyclo-ligase; COG0150 Phosphoribosylaminoimidazole (AIR) synthetase.


ensembl_gene_id: VAB18032_05395
symbol: AEB42205.1
gene_biotype: protein_coding
description:
  Glu/Leu/Phe/Val dehydrogenase dimerization region; COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: VAB18032_05405
symbol: AEB42207.1
gene_biotype: protein_coding
description:
  DNA binding domain protein, excisionase family; COG2452 Predicted site-specific integrase-resolvase.


ensembl_gene_id: VAB18032_05460
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: VAB18032_05470
symbol: AEB42220.1
gene_biotype: protein_coding
description:
  Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: VAB18032_05510
symbol: AEB42228.1
gene_biotype: protein_coding
description:
  Rieske (2fe-2S) iron-sulfur domain protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: VAB18032_05580
symbol: AEB42242.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase family 65 central catalytic; COG1554 Trehalose and maltose hydrolases (possible phosphorylases).


ensembl_gene_id: VAB18032_05605
symbol: AEB42247.1
gene_biotype: protein_coding
description:
  Monooxygenase FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_05665
symbol: vapC
gene_biotype: protein_coding
description:
  Toxin; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: VAB18032_05775
symbol: mscL
gene_biotype: protein_coding
description:
  Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: VAB18032_05790
symbol: AEB42284.1
gene_biotype: protein_coding
description:
  COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: VAB18032_05885
symbol: AEB42303.1
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COG0526 Thiol-disulfide isomerase and thioredoxins.


ensembl_gene_id: VAB18032_05910
symbol: AEB42308.1
gene_biotype: protein_coding
description:
  Ubid family decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family.


ensembl_gene_id: VAB18032_05915
symbol: ubiA
gene_biotype: protein_coding
description:
  Prenyltransferase; COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: VAB18032_05970
symbol: mqnE
gene_biotype: protein_coding
description:
  Radical sam domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.


ensembl_gene_id: VAB18032_05990
symbol: AEB42324.1
gene_biotype: protein_coding
description:
  Periplasmic binding protein; COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component.


ensembl_gene_id: VAB18032_05995
symbol: AEB42325.1
gene_biotype: protein_coding
description:
  COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: VAB18032_06000
symbol: AEB42326.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: VAB18032_06020
symbol: AEB42328.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG3324 Predicted enzyme related to lactoylglutathione lyase.


ensembl_gene_id: VAB18032_06040
symbol: mqnA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: VAB18032_06060
symbol: paaB
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase subunit PaaB; COG3460 Uncharacterized enzyme of phenylacetate metabolism.


ensembl_gene_id: VAB18032_06070
symbol: AEB42338.1
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase, paaj subunit; COG2151 Predicted metal-sulfur cluster biosynthetic enzyme.


ensembl_gene_id: VAB18032_06075
symbol: AEB42339.1
gene_biotype: protein_coding
description:
  phenylacetate-CoA oxygenase/reductase, PaaK subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: VAB18032_06080
symbol: mqnC
gene_biotype: protein_coding
description:
  Radical sam domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: VAB18032_06090
symbol: menG
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).


ensembl_gene_id: VAB18032_06105
symbol: nuoA
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: VAB18032_06110
symbol: nuoB-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: VAB18032_06115
symbol: nuoC
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.


ensembl_gene_id: VAB18032_06120
symbol: nuoD-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: VAB18032_06130
symbol: AEB42350.1
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: VAB18032_06135
symbol: AEB42351.1
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: VAB18032_06140
symbol: nuoH-2
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: VAB18032_06145
symbol: nuoI-2
gene_biotype: protein_coding
description:
  NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: VAB18032_06150
symbol: AEB42354.1
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: VAB18032_06155
symbol: nuoK-2
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: VAB18032_06160
symbol: AEB42356.1
gene_biotype: protein_coding
description:
  COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit.


ensembl_gene_id: VAB18032_06170
symbol: nuoN-2
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: VAB18032_06235
symbol: AEB42371.1
gene_biotype: protein_coding
description:
  Peptidase S8 and S53 subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: VAB18032_06260
symbol: acsA
gene_biotype: protein_coding
description:
  acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: VAB18032_06330
symbol: AEB42390.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: VAB18032_06345
symbol: hppA
gene_biotype: protein_coding
description:
  Membrane-bound proton-translocating pyrophosphatase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.


ensembl_gene_id: VAB18032_06365
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: VAB18032_06390
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: VAB18032_06455
symbol: AEB42415.1
gene_biotype: protein_coding
description:
  COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: VAB18032_06470
symbol: AEB42418.1
gene_biotype: protein_coding
description:
  rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: VAB18032_06480
symbol: AEB42420.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, emrb/qaca subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: VAB18032_06490
symbol: AEB42422.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: VAB18032_06510
symbol: ku
gene_biotype: protein_coding
description:
  Ku family containing protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.


ensembl_gene_id: VAB18032_06570
symbol: mqnD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.


ensembl_gene_id: VAB18032_06575
symbol: mqnB
gene_biotype: protein_coding
description:
  Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).


ensembl_gene_id: VAB18032_06615
symbol: AEB42447.1
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: VAB18032_06625
symbol: AEB42449.1
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.


ensembl_gene_id: VAB18032_06635
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: VAB18032_06675
symbol: AEB42459.1
gene_biotype: protein_coding
description:
  Abc-2 type transporter; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: VAB18032_06680
symbol: AEB42460.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component.


ensembl_gene_id: VAB18032_06690
symbol: AEB42462.1
gene_biotype: protein_coding
description:
  CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: VAB18032_06740
symbol: AEB42472.1
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: VAB18032_06775
symbol: AEB42479.1
gene_biotype: protein_coding
description:
  Csbd family protein; COG3237 Uncharacterized protein conserved in bacteria; Belongs to the UPF0337 (CsbD) family.


ensembl_gene_id: VAB18032_06780
symbol: AEB42480.1
gene_biotype: protein_coding
description:
  ATP-binding region atpase domain protein; COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase).


ensembl_gene_id: VAB18032_06790
symbol: AEB42482.1
gene_biotype: protein_coding
description:
  Sigma-70, region 4 type 2; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: VAB18032_06820
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: VAB18032_06825
symbol: crcB-2
gene_biotype: protein_coding
description:
  Camphor resistance CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: VAB18032_06845
symbol: AEB42493.1
gene_biotype: protein_coding
description:
  Putative ECF subfamily RNA polymerase sigma-24 subunit; COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_06880
symbol: AEB42500.1
gene_biotype: protein_coding
description:
  Molybdenum ABC transporter, periplasmic molybdate-binding protein; COG0725 ABC-type molybdate transport system, periplasmic component.


ensembl_gene_id: VAB18032_06885
symbol: AEB42501.1
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: VAB18032_06890
symbol: AEB42502.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_06915
symbol: AEB42507.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: VAB18032_06920
symbol: AEB42508.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_06940
symbol: AEB42512.1
gene_biotype: protein_coding
description:
  EmrB/QacA family drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: VAB18032_06975
symbol: AEB42519.1
gene_biotype: protein_coding
description:
  Alkanesulfonate monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_06980
symbol: AEB42520.1
gene_biotype: protein_coding
description:
  Condensation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: VAB18032_07000
symbol: AEB42524.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2764 Uncharacterized protein conserved in bacteria.


ensembl_gene_id: VAB18032_07010
symbol: AEB42526.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: VAB18032_07025
symbol: AEB42529.1
gene_biotype: protein_coding
description:
  Thiazolinyl imide reductase; COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis.


ensembl_gene_id: VAB18032_07110
symbol: AEB42546.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.


ensembl_gene_id: VAB18032_07135
symbol: AEB42551.1
gene_biotype: protein_coding
description:
  L-carnitine dehydratase/bile acid-inducible protein F; COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: VAB18032_07140
symbol: AEB42552.1
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_07145
symbol: AEB42553.1
gene_biotype: protein_coding
description:
  Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases.


ensembl_gene_id: VAB18032_07160
symbol: AEB42556.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: VAB18032_07175
symbol: AEB42559.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: VAB18032_07195
symbol: AEB42563.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: VAB18032_07215
symbol: AEB42567.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_07225
symbol: AEB42569.1
gene_biotype: protein_coding
description:
  Luciferase-like monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_07230
symbol: AEB42570.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: VAB18032_07265
symbol: AEB42577.1
gene_biotype: protein_coding
description:
  Periplasmic binding protein/laci transcriptional regulator; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_07290
symbol: AEB42582.1
gene_biotype: protein_coding
description:
  COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_07365
symbol: AEB42595.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: VAB18032_07370
symbol: AEB42596.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: VAB18032_07440
symbol: AEB42610.1
gene_biotype: protein_coding
description:
  DNA methylase N-4/N-6 domain-containing protein; COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: VAB18032_07560
symbol: AEB42632.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_07650
symbol: AEB42650.1
gene_biotype: protein_coding
description:
  Transcriptional activator domain-containing protein; COG1652 Uncharacterized protein containing LysM domain.


ensembl_gene_id: VAB18032_07710
symbol: AEB42662.1
gene_biotype: protein_coding
description:
  DNA-cytosine methyltransferase; COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: VAB18032_07860
symbol: AEB42690.1
gene_biotype: protein_coding
description:
  COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: VAB18032_07880
symbol: AEB42694.1
gene_biotype: protein_coding
description:
  COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: VAB18032_07970
symbol: AEB42712.1
gene_biotype: protein_coding
description:
  Peptidase S1 and S6 chymotrypsin/Hap; COG3591 V8-like Glu-specific endopeptidase; Belongs to the peptidase S1B family.


ensembl_gene_id: VAB18032_08020
symbol: clpP
gene_biotype: protein_coding
description:
  Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: VAB18032_08035
symbol: AEB42725.1
gene_biotype: protein_coding
description:
  2-oxoglutarate synthase; COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.


ensembl_gene_id: VAB18032_08040
symbol: AEB42726.1
gene_biotype: protein_coding
description:
  Pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.


ensembl_gene_id: VAB18032_08045
symbol: nuoA-2
gene_biotype: protein_coding
description:
  NADH-ubiquinone/plastoquinone oxidoreductase chain 3; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: VAB18032_08080
symbol: AEB42734.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, paax family protein; COG3327 Phenylacetic acid-responsive transcriptional repressor.


ensembl_gene_id: VAB18032_08090
symbol: AEB42736.1
gene_biotype: protein_coding
description:
  Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Belongs to the peptidase M17 family.


ensembl_gene_id: VAB18032_08100
symbol: AEB42738.1
gene_biotype: protein_coding
description:
  Peptidase s1 and s6 chymotrypsin/hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: VAB18032_08110
symbol: AEB42740.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: VAB18032_08220
symbol: AEB42762.1
gene_biotype: protein_coding
description:
  Phosphotransferase domain-containing protein; COG0613 Predicted metal-dependent phosphoesterases (PHP family).


ensembl_gene_id: VAB18032_08265
symbol: AEB42771.1
gene_biotype: protein_coding
description:
  COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: VAB18032_08270
symbol: AEB42772.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.


ensembl_gene_id: VAB18032_08280
symbol: AEB42774.1
gene_biotype: protein_coding
description:
  Molybdenum cofactor synthesis domain-containing protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: VAB18032_08285
symbol: AEB42775.1
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: VAB18032_08315
symbol: AEB42781.1
gene_biotype: protein_coding
description:
  Sigma factor; COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_08335
symbol: metXA
gene_biotype: protein_coding
description:
  Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.


ensembl_gene_id: VAB18032_08345
symbol: AEB42787.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: VAB18032_08355
symbol: AEB42789.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: VAB18032_08360
symbol: AEB42790.1
gene_biotype: protein_coding
description:
  Alpha-arabinofuranosidase II; COG3940 Predicted beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: VAB18032_08390
symbol: AEB42796.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG4209 ABC-type polysaccharide transport system, permease component.


ensembl_gene_id: VAB18032_08395
symbol: AEB42797.1
gene_biotype: protein_coding
description:
  Family 1 extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_08405
symbol: AEB42799.1
gene_biotype: protein_coding
description:
  Von willebrand factor type a; COG2304 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain.


ensembl_gene_id: VAB18032_08420
symbol: AEB42802.1
gene_biotype: protein_coding
description:
  COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: VAB18032_08430
symbol: AEB42804.1
gene_biotype: protein_coding
description:
  Glycosyl transferase family 39 protein; COG1928 Dolichyl-phosphate-mannose--protein O-mannosyl transferase.


ensembl_gene_id: VAB18032_08435
symbol: rsmI
gene_biotype: protein_coding
description:
  uroporphyrin-III C/tetrapyrrole methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: VAB18032_08445
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: VAB18032_08465
symbol: ksgA
gene_biotype: protein_coding
description:
  16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: VAB18032_08470
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: VAB18032_08505
symbol: glmU
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: VAB18032_08510
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: VAB18032_08515
symbol: rplY
gene_biotype: protein_coding
description:
  Ribosomal 5S rRNA e-loop binding protein ctc/l25/tl5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.


ensembl_gene_id: VAB18032_08520
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: VAB18032_08530
symbol: AEB42824.1
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes.


ensembl_gene_id: VAB18032_08535
symbol: AEB42825.1
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: VAB18032_08540
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: VAB18032_08555
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: VAB18032_08585
symbol: AEB42835.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_08605
symbol: AEB42839.1
gene_biotype: protein_coding
description:
  Basic membrane lipoprotein; COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein.


ensembl_gene_id: VAB18032_08610
symbol: AEB42840.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG3845 ABC-type uncharacterized transport systems, ATPase components.


ensembl_gene_id: VAB18032_08615
symbol: AEB42841.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG4603 ABC-type uncharacterized transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: VAB18032_08620
symbol: AEB42842.1
gene_biotype: protein_coding
description:
  Inner-membrane translocator; COG1079 Uncharacterized ABC-type transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: VAB18032_08645
symbol: add
gene_biotype: protein_coding
description:
  COG1816 Adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: VAB18032_08695
symbol: AEB42857.1
gene_biotype: protein_coding
description:
  ABC transporter CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydC; COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components.


ensembl_gene_id: VAB18032_08700
symbol: AEB42858.1
gene_biotype: protein_coding
description:
  ABC transporter CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydD; COG4988 ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components.


ensembl_gene_id: VAB18032_08735
symbol: AEB42865.1
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.


ensembl_gene_id: VAB18032_08775
symbol: AEB42873.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain-containing protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.


ensembl_gene_id: VAB18032_08795
symbol: AEB42877.1
gene_biotype: protein_coding
description:
  Flavoprotein disulfide reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: VAB18032_08810
symbol: AEB42880.1
gene_biotype: protein_coding
description:
  ABC transporter transmembrane protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_08835
symbol: AEB42885.1
gene_biotype: protein_coding
description:
  Chromosome replication initiation inhibitor protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: VAB18032_08840
symbol: AEB42886.1
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase l chain ATP-binding protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit.


ensembl_gene_id: VAB18032_08845
symbol: AEB42887.1
gene_biotype: protein_coding
description:
  Daunorubicin resistance abc transporter atpase subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: VAB18032_08885
symbol: AEB42895.1
gene_biotype: protein_coding
description:
  Maf protein; COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; Belongs to the Maf family.


ensembl_gene_id: VAB18032_08965
symbol: pckG
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.


ensembl_gene_id: VAB18032_08975
symbol: AEB42913.1
gene_biotype: protein_coding
description:
  Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.


ensembl_gene_id: VAB18032_09005
symbol: AEB42919.1
gene_biotype: protein_coding
description:
  Phoh family protein; COG1875 Predicted ATPase related to phosphate starvation-inducible protein PhoH.


ensembl_gene_id: VAB18032_09055
symbol: xseB
gene_biotype: protein_coding
description:
  Exonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: VAB18032_09070
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease vii, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: VAB18032_09075
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: VAB18032_09090
symbol: AEB42936.1
gene_biotype: protein_coding
description:
  Tripeptidyl-peptidase II; COG1404 Subtilisin-like serine proteases; Belongs to the peptidase S8 family.


ensembl_gene_id: VAB18032_09110
symbol: AEB42940.1
gene_biotype: protein_coding
description:
  Iron abc transporter substrate-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: VAB18032_09115
symbol: AEB42941.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_09120
symbol: AEB42942.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1178 ABC-type Fe3+ transport system, permease component.


ensembl_gene_id: VAB18032_09140
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: VAB18032_09145
symbol: AEB42947.1
gene_biotype: protein_coding
description:
  Peptidase U61 LD-carboxypeptidase A; COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF.


ensembl_gene_id: VAB18032_09150
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: VAB18032_09160
symbol: AEB42950.1
gene_biotype: protein_coding
description:
  Nucleoside triphosphate pyrophosphohydrolase; COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain.


ensembl_gene_id: VAB18032_09175
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.


ensembl_gene_id: VAB18032_09190
symbol: AEB42956.1
gene_biotype: protein_coding
description:
  COG1246 N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family.


ensembl_gene_id: VAB18032_09200
symbol: AEB42958.1
gene_biotype: protein_coding
description:
  XRE family plasmid maintenance system antidote protein; COG1396 Predicted transcriptional regulators.


ensembl_gene_id: VAB18032_09250
symbol: AEB42968.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain).


ensembl_gene_id: VAB18032_09260
symbol: AEB42970.1
gene_biotype: protein_coding
description:
  Fad-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: VAB18032_09305
symbol: rnz
gene_biotype: protein_coding
description:
  Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.


ensembl_gene_id: VAB18032_09325
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: VAB18032_09330
symbol: AEB42984.1
gene_biotype: protein_coding
description:
  Histidine triad (HIT) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: VAB18032_09340
symbol: AEB42986.1
gene_biotype: protein_coding
description:
  Cys/Met metabolism pyridoxal-phosphate-dependent protein; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.


ensembl_gene_id: VAB18032_09355
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor grea; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: VAB18032_09365
symbol: mca
gene_biotype: protein_coding
description:
  Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.


ensembl_gene_id: VAB18032_09375
symbol: AEB42993.1
gene_biotype: protein_coding
description:
  Diguanylate cyclase; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.


ensembl_gene_id: VAB18032_09385
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: VAB18032_09390
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: VAB18032_09515
symbol: AEB43021.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: VAB18032_09535
symbol: AEB43025.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1; COG0687 Spermidine/putrescine-binding periplasmic protein.


ensembl_gene_id: VAB18032_09540
symbol: AEB43026.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_09545
symbol: AEB43027.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1176 ABC-type spermidine/putrescine transport system, permease component I.


ensembl_gene_id: VAB18032_09550
symbol: AEB43028.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transport systems inner membrane component; COG1177 ABC-type spermidine/putrescine transport system, permease component II.


ensembl_gene_id: VAB18032_09565
symbol: AEB43031.1
gene_biotype: protein_coding
description:
  Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: VAB18032_09600
symbol: AEB43038.1
gene_biotype: protein_coding
description:
  Peptidase m15d vanx d-ala-d-ala dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.


ensembl_gene_id: VAB18032_09610
symbol: AEB43040.1
gene_biotype: protein_coding
description:
  COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: VAB18032_09665
symbol: AEB43051.1
gene_biotype: protein_coding
description:
  Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like protein; COG0166 Glucose-6-phosphate isomerase.


ensembl_gene_id: VAB18032_09680
symbol: ahcY
gene_biotype: protein_coding
description:
  S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.


ensembl_gene_id: VAB18032_09745
symbol: hpf
gene_biotype: protein_coding
description:
  Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.


ensembl_gene_id: VAB18032_09760
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.


ensembl_gene_id: VAB18032_09770
symbol: AEB43072.1
gene_biotype: protein_coding
description:
  DNA binding domain protein, excisionase family; COG1910 Periplasmic molybdate-binding protein/domain.


ensembl_gene_id: VAB18032_09795
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: VAB18032_09800
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein ftse; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: VAB18032_09805
symbol: AEB43079.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: VAB18032_09810
symbol: smpB-2
gene_biotype: protein_coding
description:
  Ssra-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: VAB18032_09820
symbol: AEB43082.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate tpp-binding domain-containing protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: VAB18032_09825
symbol: AEB43083.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: VAB18032_09865
symbol: AEB43091.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, arac family protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: VAB18032_09920
symbol: AEB43102.1
gene_biotype: protein_coding
description:
  TipAS antibiotic-recognition domain-containing protein; COG0789 Predicted transcriptional regulators.


ensembl_gene_id: VAB18032_09940
symbol: AEB43106.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: VAB18032_09960
symbol: AEB43110.1
gene_biotype: protein_coding
description:
  Bcr/CflA subfamily drug resistance transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: VAB18032_10020
symbol: AEB43122.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD/NAD(P)-binding domain-containing protein; COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases.


ensembl_gene_id: VAB18032_10080
symbol: AEB43134.1
gene_biotype: protein_coding
description:
  OmpA/MotB domain protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.


ensembl_gene_id: VAB18032_10100
symbol: AEB43138.1
gene_biotype: protein_coding
description:
  Crp/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: VAB18032_10110
symbol: AEB43140.1
gene_biotype: protein_coding
description:
  CRP/FNR family transcriptional regulator; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: VAB18032_10320
symbol: AEB43182.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase family 12; COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase 12 (cellulase H) family.


ensembl_gene_id: VAB18032_10325
symbol: AEB43183.1
gene_biotype: protein_coding
description:
  Fad dependent oxidoreductase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_10330
symbol: AEB43184.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit i; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: VAB18032_10345
symbol: AEB43187.1
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.


ensembl_gene_id: VAB18032_10350
symbol: AEB43188.1
gene_biotype: protein_coding
description:
  ATP-dependent transcriptional regulator, malt-like, luxr family protein; COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member.


ensembl_gene_id: VAB18032_10360
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent clp protease adaptor protein clps; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: VAB18032_10370
symbol: AEB43192.1
gene_biotype: protein_coding
description:
  Mov34/MPN/PAD-1 family protein; COG1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily.


ensembl_gene_id: VAB18032_10385
symbol: AEB43195.1
gene_biotype: protein_coding
description:
  Beta-lactamase domain protein; COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III.


ensembl_gene_id: VAB18032_10390
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: VAB18032_10395
symbol: AEB43197.1
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: VAB18032_10410
symbol: AEB43200.1
gene_biotype: protein_coding
description:
  N-formimino-L-glutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.


ensembl_gene_id: VAB18032_10415
symbol: AEB43201.1
gene_biotype: protein_coding
description:
  Allantoate amidohydrolase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: VAB18032_10430
symbol: AEB43204.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: VAB18032_10460
symbol: AEB43210.1
gene_biotype: protein_coding
description:
  Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: VAB18032_10465
symbol: AEB43211.1
gene_biotype: protein_coding
description:
  Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.


ensembl_gene_id: VAB18032_10500
symbol: AEB43218.1
gene_biotype: protein_coding
description:
  Cobalamin (vitamin B12) biosynthesis CbiM protein; COG0310 ABC-type Co2+ transport system, permease component.


ensembl_gene_id: VAB18032_10510
symbol: AEB43220.1
gene_biotype: protein_coding
description:
  Cobalt ABC transporter, inner membrane subunit CbiQ; COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters.


ensembl_gene_id: VAB18032_10515
symbol: AEB43221.1
gene_biotype: protein_coding
description:
  Cobalt abc transporter, atpase subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.


ensembl_gene_id: VAB18032_10575
symbol: AEB43233.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component; COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: VAB18032_10580
symbol: AEB43234.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component; COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components.


ensembl_gene_id: VAB18032_10590
symbol: AEB43236.1
gene_biotype: protein_coding
description:
  Proline iminopeptidase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: VAB18032_10625
symbol: AEB43243.1
gene_biotype: protein_coding
description:
  Glycosyltransferase, MGT family protein; COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase.


ensembl_gene_id: VAB18032_10630
symbol: AEB43244.1
gene_biotype: protein_coding
description:
  COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: VAB18032_10660
symbol: AEB43250.1
gene_biotype: protein_coding
description:
  ABC transporter ATPase/permease; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_10670
symbol: coaD-2
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: VAB18032_10715
symbol: AEB43261.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase; COG2730 Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.


ensembl_gene_id: VAB18032_10725
symbol: AEB43263.1
gene_biotype: protein_coding
description:
  Oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_10765
symbol: AEB43271.1
gene_biotype: protein_coding
description:
  COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family.


ensembl_gene_id: VAB18032_10780
symbol: AEB43274.1
gene_biotype: protein_coding
description:
  NMT1/THI5 like domain protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: VAB18032_10790
symbol: AEB43276.1
gene_biotype: protein_coding
description:
  Putative ABC transporter; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: VAB18032_10795
symbol: AEB43277.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: VAB18032_10800
symbol: AEB43278.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, PaaX family protein; COG3327 Phenylacetic acid-responsive transcriptional repressor.


ensembl_gene_id: VAB18032_10845
symbol: AEB43287.1
gene_biotype: protein_coding
description:
  Phthalate 4,5-dioxygenase reductase subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: VAB18032_10855
symbol: AEB43289.1
gene_biotype: protein_coding
description:
  Oxidoreductase subunit alpha; COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.


ensembl_gene_id: VAB18032_10950
symbol: AEB43308.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG1119 ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA.


ensembl_gene_id: VAB18032_10955
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase-like domain-containing protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: VAB18032_10960
symbol: AEB43310.1
gene_biotype: protein_coding
description:
  Thij/pfpi domain-containing protein; COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain.


ensembl_gene_id: VAB18032_10995
symbol: AEB43317.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: VAB18032_11000
symbol: AEB43318.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.


ensembl_gene_id: VAB18032_11060
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: VAB18032_11080
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: VAB18032_11090
symbol: gatC
gene_biotype: protein_coding
description:
  glutamyl-tRNA(gln) amidotransferase, c subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.


ensembl_gene_id: VAB18032_11095
symbol: gatA
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).


ensembl_gene_id: VAB18032_11105
symbol: gatB
gene_biotype: protein_coding
description:
  aspartyl/glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: VAB18032_11110
symbol: AEB43340.1
gene_biotype: protein_coding
description:
  Transketolase domain-containing protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: VAB18032_11125
symbol: AEB43343.1
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase nad-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: VAB18032_11195
symbol: AEB43357.1
gene_biotype: protein_coding
description:
  Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: VAB18032_11205
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: VAB18032_11210
symbol: AEB43360.1
gene_biotype: protein_coding
description:
  COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: VAB18032_11220
symbol: AEB43362.1
gene_biotype: protein_coding
description:
  Apbe family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: VAB18032_11245
symbol: AEB43367.1
gene_biotype: protein_coding
description:
  Putative alpha-isopropylmalate/homocitrate synthase family transferase; COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family.


ensembl_gene_id: VAB18032_11275
symbol: AEB43373.1
gene_biotype: protein_coding
description:
  Peptidase S1 and S6, chymotrypsin/Hap; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain.


ensembl_gene_id: VAB18032_11305
symbol: AEB43379.1
gene_biotype: protein_coding
description:
  5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: VAB18032_11315
symbol: leuC
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: VAB18032_11320
symbol: leuD
gene_biotype: protein_coding
description:
  Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: VAB18032_11325
symbol: AEB43383.1
gene_biotype: protein_coding
description:
  Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: VAB18032_11340
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: VAB18032_11360
symbol: gpsA
gene_biotype: protein_coding
description:
  COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: VAB18032_11370
symbol: AEB43390.1
gene_biotype: protein_coding
description:
  Modification methylase, HemK family protein; COG2890 Methylase of polypeptide chain release factors.


ensembl_gene_id: VAB18032_11410
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: VAB18032_11470
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid synthesis plsX protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: VAB18032_11475
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease iii; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: VAB18032_11480
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: VAB18032_11500
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: VAB18032_11505
symbol: AEB43415.1
gene_biotype: protein_coding
description:
  Haloacid dehalogenase domain-containing protein hydrolase; COG1011 Predicted hydrolase (HAD superfamily).


ensembl_gene_id: VAB18032_11535
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).


ensembl_gene_id: VAB18032_11560
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: VAB18032_11570
symbol: proS-2
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).


ensembl_gene_id: VAB18032_11590
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA-processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: VAB18032_11595
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: VAB18032_11600
symbol: rplS
gene_biotype: protein_coding
description:
  50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: VAB18032_11640
symbol: xerC
gene_biotype: protein_coding
description:
  Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: VAB18032_11645
symbol: AEB43443.1
gene_biotype: protein_coding
description:
  DNA protecting protein DprA; COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.


ensembl_gene_id: VAB18032_11655
symbol: AEB43445.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.


ensembl_gene_id: VAB18032_11670
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: VAB18032_11680
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: VAB18032_11690
symbol: rlmN
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: VAB18032_11705
symbol: AEB43455.1
gene_biotype: protein_coding
description:
  Rieske (2fe-2S) iron-sulfur domain protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold.


ensembl_gene_id: VAB18032_11725
symbol: AEB43459.1
gene_biotype: protein_coding
description:
  Gcn5-related n-acetyltransferase; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.


ensembl_gene_id: VAB18032_11740
symbol: nfi
gene_biotype: protein_coding
description:
  Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: VAB18032_11745
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: VAB18032_11755
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: VAB18032_11770
symbol: AEB43468.1
gene_biotype: protein_coding
description:
  NADH:flavin oxidoreductase/NADH oxidase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.


ensembl_gene_id: VAB18032_11785
symbol: AEB43471.1
gene_biotype: protein_coding
description:
  Beta-ketoadipyl CoA thiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: VAB18032_11885
symbol: AEB43491.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_11895
symbol: AEB43493.1
gene_biotype: protein_coding
description:
  Sulfate transporter/antisigma-factor antagonist stas; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor).


ensembl_gene_id: VAB18032_11920
symbol: AEB43498.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: VAB18032_11940
symbol: rimP
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: VAB18032_11945
symbol: nusA
gene_biotype: protein_coding
description:
  Transcription elongation factor NusA; Participates in both transcription termination and antitermination.


ensembl_gene_id: VAB18032_11950
symbol: AEB43504.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.


ensembl_gene_id: VAB18032_11955
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: VAB18032_11965
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: VAB18032_11995
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: VAB18032_12005
symbol: rpsO
gene_biotype: protein_coding
description:
  30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: VAB18032_12010
symbol: pnp
gene_biotype: protein_coding
description:
  Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: VAB18032_12015
symbol: AEB43517.1
gene_biotype: protein_coding
description:
  Peptidase M16 domain-containing protein; COG0612 Predicted Zn-dependent peptidases; Belongs to the peptidase M16 family.


ensembl_gene_id: VAB18032_12020
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: VAB18032_12050
symbol: thyX
gene_biotype: protein_coding
description:
  FAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.


ensembl_gene_id: VAB18032_12055
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: VAB18032_12060
symbol: rnj
gene_biotype: protein_coding
description:
  RNA-metabolising metallo-beta-lactamase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.


ensembl_gene_id: VAB18032_12100
symbol: rimO
gene_biotype: protein_coding
description:
  Miab-like tRNA modifying enzyme ylig; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: VAB18032_12105
symbol: AEB43535.1
gene_biotype: protein_coding
description:
  Cdp-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: VAB18032_12110
symbol: AEB43536.1
gene_biotype: protein_coding
description:
  Cina domain protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family.


ensembl_gene_id: VAB18032_12135
symbol: AEB43541.1
gene_biotype: protein_coding
description:
  DNA-(apurinic or apyrimidinic site) lyase; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.


ensembl_gene_id: VAB18032_12180
symbol: AEB43550.1
gene_biotype: protein_coding
description:
  NADH/ubiquinone/plastoquinone (complex i); COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit.


ensembl_gene_id: VAB18032_12195
symbol: AEB43553.1
gene_biotype: protein_coding
description:
  Monovalent cation/proton antiporter, mnhg/phag subunit; COG1320 Multisubunit Na+/H+ antiporter, MnhG subunit.


ensembl_gene_id: VAB18032_12245
symbol: recA
gene_biotype: protein_coding
description:
  recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: VAB18032_12315
symbol: AEB43577.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: VAB18032_12320
symbol: AEB43578.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 3; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: VAB18032_12325
symbol: AEB43579.1
gene_biotype: protein_coding
description:
  ABC transporter related protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: VAB18032_12345
symbol: miaB
gene_biotype: protein_coding
description:
  (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: VAB18032_12365
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: VAB18032_12370
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: VAB18032_12380
symbol: hflX
gene_biotype: protein_coding
description:
  Gtp-binding proten hflx; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: VAB18032_12390
symbol: lexA
gene_biotype: protein_coding
description:
  LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: VAB18032_12395
symbol: nrdR
gene_biotype: protein_coding
description:
  Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: VAB18032_12400
symbol: AEB43594.1
gene_biotype: protein_coding
description:
  Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.


ensembl_gene_id: VAB18032_12425
symbol: AEB43599.1
gene_biotype: protein_coding
description:
  Putative RNA polymerase, sigma-24 subunit, ECF subfamily protein; COG4941 Predicted RNA polymerase sigma factor containing a TPR repeat domain; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_12440
symbol: AEB43602.1
gene_biotype: protein_coding
description:
  Iron (metal) dependent repressor, dtxr family protein; COG1321 Mn-dependent transcriptional regulator.


ensembl_gene_id: VAB18032_12455
symbol: AEB43605.1
gene_biotype: protein_coding
description:
  CoA-binding domain-containing protein; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: VAB18032_12475
symbol: AEB43609.1
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: VAB18032_12485
symbol: dtd
gene_biotype: protein_coding
description:
  d-tyrosyl-tRNA(tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: VAB18032_12490
symbol: AEB43612.1
gene_biotype: protein_coding
description:
  Methyltransferase small; COG2890 Methylase of polypeptide chain release factors; Belongs to the methyltransferase superfamily.


ensembl_gene_id: VAB18032_12510
symbol: AEB43616.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein; COG1840 ABC-type Fe3+ transport system, periplasmic component.


ensembl_gene_id: VAB18032_12545
symbol: psuG
gene_biotype: protein_coding
description:
  Indigoidine synthase a family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: VAB18032_12570
symbol: sigA
gene_biotype: protein_coding
description:
  RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: VAB18032_12600
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: VAB18032_12635
symbol: AEB43641.1
gene_biotype: protein_coding
description:
  Deoxyribonuclease/rho motif-related TRAM; COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: VAB18032_12640
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: VAB18032_12695
symbol: AEB43653.1
gene_biotype: protein_coding
description:
  Benzoylformate decarboxylase; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: VAB18032_12700
symbol: AEB43654.1
gene_biotype: protein_coding
description:
  COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: VAB18032_12710
symbol: AEB43656.1
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase nad-binding protein; COG1024 Enoyl-CoA hydratase/carnithine racemase.


ensembl_gene_id: VAB18032_12730
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: VAB18032_12735
symbol: AEB43661.1
gene_biotype: protein_coding
description:
  Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.


ensembl_gene_id: VAB18032_12775
symbol: AEB43669.1
gene_biotype: protein_coding
description:
  Methionine-r-sulfoxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.


ensembl_gene_id: VAB18032_12900
symbol: sbcD
gene_biotype: protein_coding
description:
  Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: VAB18032_12990
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: VAB18032_13000
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: VAB18032_13180
symbol: AEB43750.1
gene_biotype: protein_coding
description:
  F420-dependent oxidoreductase, g6pdh family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_13220
symbol: AEB43758.1
gene_biotype: protein_coding
description:
  Glyoxalase/bleomycin resistance protein/dioxygenase; COG2514 Predicted ring-cleavage extradiol dioxygenase.


ensembl_gene_id: VAB18032_13230
symbol: AEB43760.1
gene_biotype: protein_coding
description:
  Ion transport 2 domain protein; COG1226 Kef-type K+ transport systems, predicted NAD-binding component.


ensembl_gene_id: VAB18032_13380
symbol: AEB43788.1
gene_biotype: protein_coding
description:
  Putative dehydrogenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_13405
symbol: AEB43793.1
gene_biotype: protein_coding
description:
  Sugar transporter; COG0477 Permeases of the major facilitator superfamily; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: VAB18032_13410
symbol: AEB43794.1
gene_biotype: protein_coding
description:
  Urease, gamma subunit; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: VAB18032_13415
symbol: ureB-2
gene_biotype: protein_coding
description:
  Urease, beta subunit; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: VAB18032_13425
symbol: ureE
gene_biotype: protein_coding
description:
  Urease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.


ensembl_gene_id: VAB18032_13430
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accessory protein uref; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: VAB18032_13435
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein ureg; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: VAB18032_13440
symbol: ureD
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: VAB18032_13545
symbol: AEB43821.1
gene_biotype: protein_coding
description:
  Putative Fe4-S4 ferredoxin; COG1139 Uncharacterized conserved protein containing a ferredoxin-like domain.


ensembl_gene_id: VAB18032_13650
symbol: AEB43842.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components.


ensembl_gene_id: VAB18032_13660
symbol: AEB43844.1
gene_biotype: protein_coding
description:
  Iron-hydroxamate transporter permease subunit; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: VAB18032_13665
symbol: AEB43845.1
gene_biotype: protein_coding
description:
  FAD-binding 9, siderophore-interacting domain-containing protein; COG2375 Siderophore-interacting protein.


ensembl_gene_id: VAB18032_13700
symbol: AEB43852.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD-binding subunit; COG1017 Hemoglobin-like flavoprotein; Belongs to the globin family.


ensembl_gene_id: VAB18032_13745
symbol: AEB43861.1
gene_biotype: protein_coding
description:
  Acylneuraminate cytidylyltransferase; COG1861 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase homolog.


ensembl_gene_id: VAB18032_13760
symbol: AEB43864.1
gene_biotype: protein_coding
description:
  Pyridoxal-phosphate-dependent aminotransferase enzyme; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: VAB18032_13765
symbol: AEB43865.1
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein CapD; COG1086 Predicted nucleoside-diphosphate sugar epimerases.


ensembl_gene_id: VAB18032_13780
symbol: AEB43868.1
gene_biotype: protein_coding
description:
  Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.


ensembl_gene_id: VAB18032_13800
symbol: AEB43872.1
gene_biotype: protein_coding
description:
  Cdp-glycerol:poly(glycerophosphate) glycerophosphotransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: VAB18032_13835
symbol: ispD-2
gene_biotype: protein_coding
description:
  2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: VAB18032_13840
symbol: AEB43880.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component.


ensembl_gene_id: VAB18032_13845
symbol: AEB43881.1
gene_biotype: protein_coding
description:
  ABC-2 type transporter; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.


ensembl_gene_id: VAB18032_13875
symbol: AEB43887.1
gene_biotype: protein_coding
description:
  TRAP transporter solute receptor TAXI family protein; COG2358 TRAP-type uncharacterized transport system, periplasmic component.


ensembl_gene_id: VAB18032_13900
symbol: glgB
gene_biotype: protein_coding
description:
  Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: VAB18032_13905
symbol: glgE
gene_biotype: protein_coding
description:
  Alpha amylase catalytic sub domain protein; Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.


ensembl_gene_id: VAB18032_13910
symbol: AEB43894.1
gene_biotype: protein_coding
description:
  Putative short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_13915
symbol: AEB43895.1
gene_biotype: protein_coding
description:
  3-ketosteroid-delta-1-dehydrogenase; COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.


ensembl_gene_id: VAB18032_13935
symbol: AEB43899.1
gene_biotype: protein_coding
description:
  PilT domain-containing protein; COG1487 Predicted nucleic acid-binding protein, contains PIN domain.


ensembl_gene_id: VAB18032_13945
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: VAB18032_13990
symbol: AEB43910.1
gene_biotype: protein_coding
description:
  Degt/dnrj/eryc1/strs aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: VAB18032_14015
symbol: AEB43915.1
gene_biotype: protein_coding
description:
  Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family protein; COG0110 Acetyltransferase (isoleucine patch superfamily).


ensembl_gene_id: VAB18032_14050
symbol: AEB43922.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, lysr family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: VAB18032_14090
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: VAB18032_14105
symbol: AEB43933.1
gene_biotype: protein_coding
description:
  Antibiotic biosynthesis monooxygenase; COG2329 Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides.


ensembl_gene_id: VAB18032_14160
symbol: AEB43944.1
gene_biotype: protein_coding
description:
  Epoxide hydrolase domain protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: VAB18032_14190
symbol: AEB43950.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 28 subunit, sig b/f/g subfamily protein; COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_14220
symbol: AEB43956.1
gene_biotype: protein_coding
description:
  Amino acid adenylation domain-containing protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: VAB18032_14255
symbol: AEB43963.1
gene_biotype: protein_coding
description:
  COG5297 Cellobiohydrolase A (1,4-beta-cellobiosidase A); Belongs to the glycosyl hydrolase family 6.


ensembl_gene_id: VAB18032_14320
symbol: AEB43976.1
gene_biotype: protein_coding
description:
  Dolichyl-phosphate beta-D-mannosyltransferase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: VAB18032_14350
symbol: AEB43982.1
gene_biotype: protein_coding
description:
  Cytidyltransferase-like protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: VAB18032_14355
symbol: AEB43983.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG4221 Short-chain alcohol dehydrogenase of unknown specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: VAB18032_14375
symbol: AEB43987.1
gene_biotype: protein_coding
description:
  Daunorubicin resistance ABC transporter ATPase; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: VAB18032_14500
symbol: AEB44012.1
gene_biotype: protein_coding
description:
  Putative muramoyl-pentapeptide carboxypeptidase; COG3409 Putative peptidoglycan-binding domain-containing protein.


ensembl_gene_id: VAB18032_14505
symbol: AEB44013.1
gene_biotype: protein_coding
description:
  Histidine triad (hit) protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases.


ensembl_gene_id: VAB18032_14520
symbol: AEB44016.1
gene_biotype: protein_coding
description:
  CDP-alcohol phosphatidyltransferase; COG0558 Phosphatidylglycerophosphate synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: VAB18032_14540
symbol: pdxS
gene_biotype: protein_coding
description:
  Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.


ensembl_gene_id: VAB18032_14545
symbol: pdxT
gene_biotype: protein_coding
description:
  Sno glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.


ensembl_gene_id: VAB18032_14570
symbol: vapC-2
gene_biotype: protein_coding
description:
  PilT protein domain-containing protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: VAB18032_14615
symbol: AEB44035.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG4152 ABC-type uncharacterized transport system, ATPase component.


ensembl_gene_id: VAB18032_14700
symbol: AEB44052.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_14705
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease ruvc; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: VAB18032_14710
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: VAB18032_14715
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: VAB18032_14725
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: VAB18032_14730
symbol: secF
gene_biotype: protein_coding
description:
  Protein-export membrane protein secf; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: VAB18032_14735
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: VAB18032_14740
symbol: AEB44060.1
gene_biotype: protein_coding
description:
  RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: VAB18032_14765
symbol: AEB44065.1
gene_biotype: protein_coding
description:
  Thioesterase superfamily protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.


ensembl_gene_id: VAB18032_14790
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: VAB18032_14820
symbol: AEB44076.1
gene_biotype: protein_coding
description:
  Recombination factor protein RarA; COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase.


ensembl_gene_id: VAB18032_14845
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: VAB18032_14850
symbol: AEB44082.1
gene_biotype: protein_coding
description:
  Holliday junction resolvase yqgf; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: VAB18032_14855
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.


ensembl_gene_id: VAB18032_14875
symbol: AEB44087.1
gene_biotype: protein_coding
description:
  Shikimate-5-dehydrogenase; COG0169 Shikimate 5-dehydrogenase; Belongs to the shikimate dehydrogenase family.


ensembl_gene_id: VAB18032_14915
symbol: AEB44095.1
gene_biotype: protein_coding
description:
  Oligosaccharide biosynthesis Alg14-like protein; COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase.


ensembl_gene_id: VAB18032_14935
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: VAB18032_14940
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: VAB18032_14945
symbol: AEB44101.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase caa3-type, assembly factor ctag-related protein; COG3336 Predicted membrane protein.


ensembl_gene_id: VAB18032_14955
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: VAB18032_14960
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: VAB18032_14965
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor p; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: VAB18032_14970
symbol: nusB
gene_biotype: protein_coding
description:
  Nusb antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: VAB18032_14980
symbol: pyrR
gene_biotype: protein_coding
description:
  Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.


ensembl_gene_id: VAB18032_14985
symbol: pyrB
gene_biotype: protein_coding
description:
  COG0540 Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: VAB18032_14990
symbol: pyrC
gene_biotype: protein_coding
description:
  Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.


ensembl_gene_id: VAB18032_15005
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: VAB18032_15010
symbol: bioA
gene_biotype: protein_coding
description:
  Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: VAB18032_15015
symbol: pyrF
gene_biotype: protein_coding
description:
  COG0284 Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.


ensembl_gene_id: VAB18032_15030
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: VAB18032_15035
symbol: AEB44119.1
gene_biotype: protein_coding
description:
  Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: VAB18032_15040
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: VAB18032_15045
symbol: priA
gene_biotype: protein_coding
description:
  Hypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: VAB18032_15060
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: VAB18032_15065
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: VAB18032_15070
symbol: AEB44126.1
gene_biotype: protein_coding
description:
  Fmu (Sun) domain-containing protein; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: VAB18032_15095
symbol: AEB44131.1
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein ribd; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: VAB18032_15110
symbol: ribBA
gene_biotype: protein_coding
description:
  Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: VAB18032_15115
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.


ensembl_gene_id: VAB18032_15125
symbol: AEB44137.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: VAB18032_15130
symbol: AEB44138.1
gene_biotype: protein_coding
description:
  Glutamine ABC transporter permease protein; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: VAB18032_15145
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: VAB18032_15155
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor if-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: VAB18032_15165
symbol: rplT
gene_biotype: protein_coding
description:
  Ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: VAB18032_15170
symbol: AEB44146.1
gene_biotype: protein_coding
description:
  tRNA/rRNA methyltransferase; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: VAB18032_15175
symbol: pheS
gene_biotype: protein_coding
description:
  COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: VAB18032_15180
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase subunit beta; COG0073 EMAP domain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: VAB18032_15185
symbol: AEB44149.1
gene_biotype: protein_coding
description:
  Cyclic nucleotide-binding protein; COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases.


ensembl_gene_id: VAB18032_15205
symbol: AEB44153.1
gene_biotype: protein_coding
description:
  Nucleotide sugar dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: VAB18032_15220
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: VAB18032_15225
symbol: argJ
gene_biotype: protein_coding
description:
  Bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.


ensembl_gene_id: VAB18032_15230
symbol: argB
gene_biotype: protein_coding
description:
  Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: VAB18032_15235
symbol: argD
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: VAB18032_15240
symbol: AEB44160.1
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: VAB18032_15275
symbol: AEB44167.1
gene_biotype: protein_coding
description:
  Luciferase-like protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_15335
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: VAB18032_15375
symbol: nadK
gene_biotype: protein_coding
description:
  ATP-nad/acox kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: VAB18032_15385
symbol: AEB44189.1
gene_biotype: protein_coding
description:
  Thiamin pyrophosphokinase catalytic domain-containing protein; COG4825 Uncharacterized membrane-anchored protein conserved in bacteria.


ensembl_gene_id: VAB18032_15415
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.


ensembl_gene_id: VAB18032_15435
symbol: xerD
gene_biotype: protein_coding
description:
  Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: VAB18032_15445
symbol: AEB44201.1
gene_biotype: protein_coding
description:
  Chromosome segregation and condensation protein scpa; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: VAB18032_15450
symbol: AEB44202.1
gene_biotype: protein_coding
description:
  Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: VAB18032_15455
symbol: AEB44203.1
gene_biotype: protein_coding
description:
  Pseudouridine synthase; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: VAB18032_15465
symbol: der
gene_biotype: protein_coding
description:
  GTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: VAB18032_15675
symbol: AEB44247.1
gene_biotype: protein_coding
description:
  Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.


ensembl_gene_id: VAB18032_15810
symbol: AEB44272.1
gene_biotype: protein_coding
description:
  Appr-1-p processing domain-containing protein; COG2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1.


ensembl_gene_id: VAB18032_15965
symbol: AEB44303.1
gene_biotype: protein_coding
description:
  DNA methylase n-4/n-6 domain protein; COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family.


ensembl_gene_id: VAB18032_16220
symbol: cas1
gene_biotype: protein_coding
description:
  CRISPR-associated Cas1 family protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: VAB18032_16265
symbol: AEB44359.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 1 protein; COG1653 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_16335
symbol: AEB44373.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: VAB18032_16340
symbol: AEB44374.1
gene_biotype: protein_coding
description:
  Putative ABC transporter substrate-binding protein; COG4521 ABC-type taurine transport system, periplasmic component.


ensembl_gene_id: VAB18032_16345
symbol: AEB44375.1
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: VAB18032_16365
symbol: orfU
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain-containing protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: VAB18032_16370
symbol: abyT
gene_biotype: protein_coding
description:
  Oleoyl-(acyl-carrier-protein) hydrolase; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: VAB18032_16390
symbol: abyF4
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4172 ABC-type uncharacterized transport system, duplicated ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_16440
symbol: abyA5
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); Belongs to the UPF0255 family.


ensembl_gene_id: VAB18032_16445
symbol: abyA4
gene_biotype: protein_coding
description:
  Dehydrogenase catalytic domain-containing protein; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: VAB18032_16475
symbol: AEB44401.1
gene_biotype: protein_coding
description:
  SARP family pathway specific transcriptional activator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: VAB18032_16480
symbol: AEB44402.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_16505
symbol: orfP
gene_biotype: protein_coding
description:
  protein-L-isoaspartate(D-aspartate) O-methyltransferase; COG2518 Protein-L-isoaspartate carboxylmethyltransferase.


ensembl_gene_id: VAB18032_16530
symbol: AEB44410.1
gene_biotype: protein_coding
description:
  Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: VAB18032_16535
symbol: AEB44411.1
gene_biotype: protein_coding
description:
  Putative rhizopine-binding ABC transporter protein; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_16665
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: VAB18032_16685
symbol: AEB44441.1
gene_biotype: protein_coding
description:
  Periplasmic solute binding protein; COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: VAB18032_16850
symbol: AEB44474.1
gene_biotype: protein_coding
description:
  COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: VAB18032_16960
symbol: AEB44496.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase, zinc-binding protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: VAB18032_17030
symbol: AEB44510.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.


ensembl_gene_id: VAB18032_17040
symbol: AEB44512.1
gene_biotype: protein_coding
description:
  COG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: VAB18032_17070
symbol: AEB44518.1
gene_biotype: protein_coding
description:
  Putative oxidoreductase; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: VAB18032_17165
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: VAB18032_17265
symbol: AEB44555.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_17425
symbol: AEB44587.1
gene_biotype: protein_coding
description:
  Succinate semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: VAB18032_17430
symbol: AEB44588.1
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter ATP-binding protein, CUT1 family; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_17470
symbol: AEB44596.1
gene_biotype: protein_coding
description:
  Bnr repeat-containing protein; COG5184 Alpha-tubulin suppressor and related RCC1 domain-containing proteins.


ensembl_gene_id: VAB18032_17505
symbol: AEB44603.1
gene_biotype: protein_coding
description:
  Putative peptidase; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: VAB18032_17520
symbol: AEB44606.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase family protein; COG3507 Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.


ensembl_gene_id: VAB18032_17525
symbol: AEB44607.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: VAB18032_17540
symbol: AEB44610.1
gene_biotype: protein_coding
description:
  LuxR family two component transcriptional regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_17565
symbol: AEB44615.1
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; COG1680 Beta-lactamase class C and other penicillin binding proteins.


ensembl_gene_id: VAB18032_17605
symbol: AEB44623.1
gene_biotype: protein_coding
description:
  Pyridine nucleotide-disulfide oxidoreductase dimerization region; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: VAB18032_17705
symbol: AEB44643.1
gene_biotype: protein_coding
description:
  ATP-dependent transcriptional regulator, malt-like, luxr family protein; COG2771 DNA-binding HTH domain-containing proteins.


ensembl_gene_id: VAB18032_17730
symbol: AEB44648.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase zinc-binding domain protein; COG1062 Zn-dependent alcohol dehydrogenases, class III.


ensembl_gene_id: VAB18032_17785
symbol: AEB44659.1
gene_biotype: protein_coding
description:
  4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.


ensembl_gene_id: VAB18032_17790
symbol: AEB44660.1
gene_biotype: protein_coding
description:
  Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.


ensembl_gene_id: VAB18032_17800
symbol: AEB44662.1
gene_biotype: protein_coding
description:
  2-hydroxymuconic semialdehyde dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: VAB18032_17810
symbol: AEB44664.1
gene_biotype: protein_coding
description:
  Microcompartments protein; COG4577 Carbon dioxide concentrating mechanism/carboxysome shell protein.


ensembl_gene_id: VAB18032_17830
symbol: AEB44668.1
gene_biotype: protein_coding
description:
  5-oxoprolinase (ATP-hydrolyzing); COG0146 N-methylhydantoinase B/acetone carboxylase, alpha subunit.


ensembl_gene_id: VAB18032_17840
symbol: AEB44670.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate enzyme-like TPP binding region; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: VAB18032_17870
symbol: AEB44676.1
gene_biotype: protein_coding
description:
  Abc transporter atpase subunit; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: VAB18032_17920
symbol: AEB44686.1
gene_biotype: protein_coding
description:
  Putative anti-sigma regulatory factor, serine/threonine protein kinase; COG3920 Signal transduction histidine kinase.


ensembl_gene_id: VAB18032_18030
symbol: AEB44708.1
gene_biotype: protein_coding
description:
  O-methyltransferase involved in albicidin biosynthesis protein; COG0500 SAM-dependent methyltransferases.


ensembl_gene_id: VAB18032_18045
symbol: AEB44711.1
gene_biotype: protein_coding
description:
  Putative multi-domain non-ribosomal peptide synthetase; COG2521 Predicted archaeal methyltransferase.


ensembl_gene_id: VAB18032_18055
symbol: AEB44713.1
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: VAB18032_18075
symbol: AEB44717.1
gene_biotype: protein_coding
description:
  Putative GntR family transcriptional regulator; COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs.


ensembl_gene_id: VAB18032_18120
symbol: AEB44726.1
gene_biotype: protein_coding
description:
  Two component system response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_18145
symbol: AEB44731.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, EmrB/QacA subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: VAB18032_18160
symbol: accA
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: VAB18032_18170
symbol: AEB44736.1
gene_biotype: protein_coding
description:
  COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: VAB18032_18195
symbol: AEB44741.1
gene_biotype: protein_coding
description:
  HAD-superfamily hydrolase, subfamily IIA; COG0647 Predicted sugar phosphatases of the HAD superfamily.


ensembl_gene_id: VAB18032_18235
symbol: AEB44749.1
gene_biotype: protein_coding
description:
  Galactonate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: VAB18032_18240
symbol: AEB44750.1
gene_biotype: protein_coding
description:
  Acetoin dehydrogenase alpha subunit; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: VAB18032_18245
symbol: AEB44751.1
gene_biotype: protein_coding
description:
  Dehydrogenase E1 component; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: VAB18032_18250
symbol: AEB44752.1
gene_biotype: protein_coding
description:
  3-ketoacyl-(ACP) reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_18285
symbol: AEB44759.1
gene_biotype: protein_coding
description:
  sugar-ABC transporter transmembrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: VAB18032_18295
symbol: AEB44761.1
gene_biotype: protein_coding
description:
  Racemase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily; Belongs to the mandelate racemase/muconate lactonizing enzyme family.


ensembl_gene_id: VAB18032_18315
symbol: AEB44765.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter ATP-binding protein; COG1129 ABC-type sugar transport system, ATPase component.


ensembl_gene_id: VAB18032_18320
symbol: AEB44766.1
gene_biotype: protein_coding
description:
  Sugar ABC transporter permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: VAB18032_18325
symbol: AEB44767.1
gene_biotype: protein_coding
description:
  Ribose transporter permease RbsC; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: VAB18032_18330
symbol: AEB44768.1
gene_biotype: protein_coding
description:
  Substrate-binding component of ABC transporter; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_18360
symbol: azoR
gene_biotype: protein_coding
description:
  NAD(P)H dehydrogenase (quinone); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: VAB18032_18370
symbol: AEB44776.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: VAB18032_18375
symbol: AEB44777.1
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: VAB18032_18385
symbol: AEB44779.1
gene_biotype: protein_coding
description:
  Putative NRPS-type-I PKS fusion protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: VAB18032_18400
symbol: AEB44782.1
gene_biotype: protein_coding
description:
  AraC/XylS family transcriptional regulator; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: VAB18032_18430
symbol: AEB44788.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: VAB18032_18460
symbol: AEB44794.1
gene_biotype: protein_coding
description:
  Flavin reductase domain-containing protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: VAB18032_18515
symbol: AEB44805.1
gene_biotype: protein_coding
description:
  Ricin b lectin; COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: VAB18032_18710
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: VAB18032_18735
symbol: AEB44849.1
gene_biotype: protein_coding
description:
  TrkA-C domain protein; COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels.


ensembl_gene_id: VAB18032_18770
symbol: AEB44856.1
gene_biotype: protein_coding
description:
  Aminoglycoside phosphotransferase; COG0454 Histone acetyltransferase HPA2 and related acetyltransferases.


ensembl_gene_id: VAB18032_18855
symbol: AEB44873.1
gene_biotype: protein_coding
description:
  Monooxygenase fad-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_18860
symbol: AEB44874.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, atpase, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: VAB18032_18925
symbol: AEB44887.1
gene_biotype: protein_coding
description:
  Class II aldolase/adducin family protein; COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.


ensembl_gene_id: VAB18032_18930
symbol: AEB44888.1
gene_biotype: protein_coding
description:
  NMT1/THI5 like domain-containing protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: VAB18032_18935
symbol: AEB44889.1
gene_biotype: protein_coding
description:
  Binding-protein-dependent transporter inner membrane component; COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component.


ensembl_gene_id: VAB18032_18945
symbol: AEB44891.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component.


ensembl_gene_id: VAB18032_18955
symbol: AEB44893.1
gene_biotype: protein_coding
description:
  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold.


ensembl_gene_id: VAB18032_19040
symbol: AEB44910.1
gene_biotype: protein_coding
description:
  Low molecular weight phosphotyrosine protein phosphatase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: VAB18032_19140
symbol: cobB
gene_biotype: protein_coding
description:
  Silent information regulator protein Sir2; COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: VAB18032_19190
symbol: AEB44940.1
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: VAB18032_19220
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin importer ATP-binding subunit; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: VAB18032_19300
symbol: AEB44962.1
gene_biotype: protein_coding
description:
  FAD-dependent monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_19305
symbol: AEB44963.1
gene_biotype: protein_coding
description:
  Drug resistance transporter, bcr/cfla subfamily protein; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: VAB18032_19320
symbol: AEB44966.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily protein; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: VAB18032_19390
symbol: AEB44980.1
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, inner membrane subunit CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.


ensembl_gene_id: VAB18032_19395
symbol: AEB44981.1
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, inner membrane subunit; COG4208 ABC-type sulfate transport system, permease component.


ensembl_gene_id: VAB18032_19400
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate ABC transporter, ATPase subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: VAB18032_19410
symbol: AEB44984.1
gene_biotype: protein_coding
description:
  PfkB domain-containing protein; COG0524 Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: VAB18032_19460
symbol: AEB44994.1
gene_biotype: protein_coding
description:
  Transporter permease; COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components.


ensembl_gene_id: VAB18032_19485
symbol: AEB44999.1
gene_biotype: protein_coding
description:
  2-deoxy-D-gluconate 3-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_19510
symbol: AEB45004.1
gene_biotype: protein_coding
description:
  Xylose abc transporter, substrate-binding protein; COG4213 ABC-type xylose transport system, periplasmic component.


ensembl_gene_id: VAB18032_19550
symbol: AEB45012.1
gene_biotype: protein_coding
description:
  Periplasmic binding protein/LacI transcriptional regulator; COG1879 ABC-type sugar transport system, periplasmic component.


ensembl_gene_id: VAB18032_19650
symbol: AEB45032.1
gene_biotype: protein_coding
description:
  Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: VAB18032_19665
symbol: AEB45035.1
gene_biotype: protein_coding
description:
  Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).


ensembl_gene_id: VAB18032_19700
symbol: AEB45042.1
gene_biotype: protein_coding
description:
  4-hydroxybenzoate 3-monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_19740
symbol: AEB45050.1
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactonase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: VAB18032_19745
symbol: AEB45051.1
gene_biotype: protein_coding
description:
  3-oxoadipate enol-lactonase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.


ensembl_gene_id: VAB18032_19755
symbol: AEB45053.1
gene_biotype: protein_coding
description:
  Na+/h+ antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: VAB18032_19765
symbol: AEB45055.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD-binding subunit; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: VAB18032_19850
symbol: AEB45072.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter periplasmic phosphate- binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: VAB18032_19855
symbol: AEB45073.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: VAB18032_19860
symbol: AEB45074.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter inner membrane subunit PstA; COG0581 ABC-type phosphate transport system, permease component.


ensembl_gene_id: VAB18032_19865
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: VAB18032_19920
symbol: AEB45086.1
gene_biotype: protein_coding
description:
  Nitrilase/cyanide hydratase and apolipoprotein N- acyltransferase; COG0388 Predicted amidohydrolase.


ensembl_gene_id: VAB18032_19975
symbol: AEB45097.1
gene_biotype: protein_coding
description:
  NADH/Ubiquinone/plastoquinone (complex I); COG0651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit.


ensembl_gene_id: VAB18032_20005
symbol: AEB45103.1
gene_biotype: protein_coding
description:
  NarL family two-component response regulator; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_20035
symbol: AEB45109.1
gene_biotype: protein_coding
description:
  Putative ABC transporter permease protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: VAB18032_20050
symbol: AEB45112.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.


ensembl_gene_id: VAB18032_20060
symbol: AEB45114.1
gene_biotype: protein_coding
description:
  COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.


ensembl_gene_id: VAB18032_20155
symbol: AEB45131.1
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: VAB18032_20185
symbol: AEB45137.1
gene_biotype: protein_coding
description:
  Deaminase-reductase domain-containing protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis.


ensembl_gene_id: VAB18032_20235
symbol: AEB45147.1
gene_biotype: protein_coding
description:
  COG4779 ABC-type enterobactin transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: VAB18032_20410
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: VAB18032_20425
symbol: rbpA
gene_biotype: protein_coding
description:
  Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.


ensembl_gene_id: VAB18032_20470
symbol: AEB45194.1
gene_biotype: protein_coding
description:
  LysR substrate-binding protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: VAB18032_20520
symbol: AEB45204.1
gene_biotype: protein_coding
description:
  Integrase family protein; COG4974 Site-specific recombinase XerD; Belongs to the 'phage' integrase family.


ensembl_gene_id: VAB18032_20590
symbol: AEB45218.1
gene_biotype: protein_coding
description:
  GCN5-related N-acetyltransferase; COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.


ensembl_gene_id: VAB18032_20640
symbol: AEB45228.1
gene_biotype: protein_coding
description:
  COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: VAB18032_20655
symbol: AEB45231.1
gene_biotype: protein_coding
description:
  COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: VAB18032_20680
symbol: AEB45236.1
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.


ensembl_gene_id: VAB18032_20685
symbol: AEB45237.1
gene_biotype: protein_coding
description:
  Flavin reductase-like protein; COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.


ensembl_gene_id: VAB18032_20700
symbol: AEB45240.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_20770
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: VAB18032_20775
symbol: cobB-2
gene_biotype: protein_coding
description:
  Silent information regulator protein sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily.


ensembl_gene_id: VAB18032_20815
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system h protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: VAB18032_20840
symbol: AEB45268.1
gene_biotype: protein_coding
description:
  Protein serine phosphatase with gaf(s) sensor(s); COG2208 Serine phosphatase RsbU, regulator of sigma subunit.


ensembl_gene_id: VAB18032_20845
symbol: AEB45269.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: VAB18032_20890
symbol: selA
gene_biotype: protein_coding
description:
  Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: VAB18032_20905
symbol: AEB45281.1
gene_biotype: protein_coding
description:
  Formate dehydrogenase subunit alpha; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: VAB18032_20910
symbol: AEB45282.1
gene_biotype: protein_coding
description:
  Formate dehydrogenase, alpha subunit; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.


ensembl_gene_id: VAB18032_20965
symbol: AEB45293.1
gene_biotype: protein_coding
description:
  Mycothiol-dependent formaldehyde dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III.


ensembl_gene_id: VAB18032_21010
symbol: AEB45302.1
gene_biotype: protein_coding
description:
  Putative F420-dependent oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_21095
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: VAB18032_21180
symbol: AEB45336.1
gene_biotype: protein_coding
description:
  Bifunctional D-altronate/D-mannonate dehydratase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily.


ensembl_gene_id: VAB18032_21190
symbol: AEB45338.1
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxyphosphogluconate aldolase/4- hydroxy-2-oxoglutarate aldolase; COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase.


ensembl_gene_id: VAB18032_21200
symbol: AEB45340.1
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter membrane protein; COG0395 ABC-type sugar transport system, permease component.


ensembl_gene_id: VAB18032_21205
symbol: AEB45341.1
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: VAB18032_21235
symbol: AEB45347.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ecf subfamily protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_21455
symbol: AEB45391.1
gene_biotype: protein_coding
description:
  Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member; COG4826 Serine protease inhibitor; Belongs to the serpin family.


ensembl_gene_id: VAB18032_21470
symbol: AEB45394.1
gene_biotype: protein_coding
description:
  RNA helicase; COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster.


ensembl_gene_id: VAB18032_21565
symbol: AEB45413.1
gene_biotype: protein_coding
description:
  Monooxygenase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_21590
symbol: AEB45418.1
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.


ensembl_gene_id: VAB18032_21610
symbol: AEB45422.1
gene_biotype: protein_coding
description:
  Binding-protein dependent transport system inner membrane protein; COG1175 ABC-type sugar transport systems, permease components.


ensembl_gene_id: VAB18032_21775
symbol: AEB45455.1
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase family 2; COG5479 Uncharacterized protein potentially involved in peptidoglycan biosynthesis.


ensembl_gene_id: VAB18032_21880
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: VAB18032_21885
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: VAB18032_21890
symbol: kdpC
gene_biotype: protein_coding
description:
  K+ transporting ATPase, KdpC subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: VAB18032_21950
symbol: AEB45490.1
gene_biotype: protein_coding
description:
  Metallophosphoesterase; COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases.


ensembl_gene_id: VAB18032_21990
symbol: AEB45498.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase.


ensembl_gene_id: VAB18032_22115
symbol: AEB45523.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase.


ensembl_gene_id: VAB18032_22155
symbol: AEB45531.1
gene_biotype: protein_coding
description:
  Carbamoyl-phosphate synthase, large subunit, CarB; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ).


ensembl_gene_id: VAB18032_22160
symbol: AEB45532.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: VAB18032_22165
symbol: AEB45533.1
gene_biotype: protein_coding
description:
  Thioesterase type II; COG3208 Predicted thioesterase involved in non-ribosomal peptide biosynthesis.


ensembl_gene_id: VAB18032_22185
symbol: AEB45537.1
gene_biotype: protein_coding
description:
  GHMP kinase; COG4542 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase.


ensembl_gene_id: VAB18032_22195
symbol: AEB45539.1
gene_biotype: protein_coding
description:
  COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: VAB18032_22210
symbol: AEB45542.1
gene_biotype: protein_coding
description:
  McnC protein; COG1020 Non-ribosomal peptide synthetase modules and related proteins; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: VAB18032_22225
symbol: AEB45545.1
gene_biotype: protein_coding
description:
  Aminotransferase; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.


ensembl_gene_id: VAB18032_22230
symbol: AEB45546.1
gene_biotype: protein_coding
description:
  4-hydroxyphenylpyruvic acid dioxygenase; COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.


ensembl_gene_id: VAB18032_22240
symbol: AEB45548.1
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.


ensembl_gene_id: VAB18032_22255
symbol: AEB45551.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate binding domain-containing protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: VAB18032_22275
symbol: AEB45555.1
gene_biotype: protein_coding
description:
  3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_22320
symbol: AEB45564.1
gene_biotype: protein_coding
description:
  Carboxymuconolactone decarboxylase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: VAB18032_22335
symbol: AEB45567.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.


ensembl_gene_id: VAB18032_22355
symbol: AEB45571.1
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate transporter ATP-binding subunit; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_22370
symbol: AEB45574.1
gene_biotype: protein_coding
description:
  Glycosyl hydrolase BNR repeat-containing protein; COG4447 Uncharacterized protein related to plant photosystem II stability/assembly factor.


ensembl_gene_id: VAB18032_22375
symbol: AEB45575.1
gene_biotype: protein_coding
description:
  Pyridoxamine kinase; COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; Belongs to the pyridoxine kinase family.


ensembl_gene_id: VAB18032_22470
symbol: AEB45594.1
gene_biotype: protein_coding
description:
  Rieske (2Fe-2S) domain-containing protein; COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases.


ensembl_gene_id: VAB18032_22480
symbol: AEB45596.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.


ensembl_gene_id: VAB18032_22485
symbol: AEB45597.1
gene_biotype: protein_coding
description:
  ABC transporter ATP-binding protein; COG4674 Uncharacterized ABC-type transport system, ATPase component.


ensembl_gene_id: VAB18032_22490
symbol: AEB45598.1
gene_biotype: protein_coding
description:
  COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: VAB18032_22500
symbol: AEB45600.1
gene_biotype: protein_coding
description:
  ABC transporter substrate-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: VAB18032_22505
symbol: AEB45601.1
gene_biotype: protein_coding
description:
  Regulatory protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.


ensembl_gene_id: VAB18032_22530
symbol: ureD-2
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: VAB18032_22535
symbol: ureG-2
gene_biotype: protein_coding
description:
  Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: VAB18032_22550
symbol: ureB
gene_biotype: protein_coding
description:
  Urease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family.


ensembl_gene_id: VAB18032_22555
symbol: ureA
gene_biotype: protein_coding
description:
  Urease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family.


ensembl_gene_id: VAB18032_22565
symbol: AEB45613.1
gene_biotype: protein_coding
description:
  Polar amino acid abc transporter, inner membrane subunit; COG0765 ABC-type amino acid transport system, permease component.


ensembl_gene_id: VAB18032_22605
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: VAB18032_22640
symbol: AEB45628.1
gene_biotype: protein_coding
description:
  Aliphatic sulfonates family abc transporter, periplasmic ligand-binding protein; COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components.


ensembl_gene_id: VAB18032_22650
symbol: ssuB
gene_biotype: protein_coding
description:
  ABC transporter-like protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: VAB18032_22670
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: VAB18032_22720
symbol: AEB45644.1
gene_biotype: protein_coding
description:
  ABC transporter permease/ATP-binding protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_22725
symbol: AEB45645.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_22745
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase, TatC subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: VAB18032_22750
symbol: tatA
gene_biotype: protein_coding
description:
  Twin arginine translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: VAB18032_22780
symbol: pafA
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.


ensembl_gene_id: VAB18032_22790
symbol: AEB45658.1
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: VAB18032_22795
symbol: AEB45659.1
gene_biotype: protein_coding
description:
  COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: VAB18032_22800
symbol: AEB45660.1
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.


ensembl_gene_id: VAB18032_22825
symbol: prcA
gene_biotype: protein_coding
description:
  Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.


ensembl_gene_id: VAB18032_22830
symbol: prcB
gene_biotype: protein_coding
description:
  20S proteasome a and b subunits; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.


ensembl_gene_id: VAB18032_22835
symbol: pup
gene_biotype: protein_coding
description:
  Hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.


ensembl_gene_id: VAB18032_22850
symbol: arc
gene_biotype: protein_coding
description:
  Aaa atpase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.


ensembl_gene_id: VAB18032_22865
symbol: AEB45673.1
gene_biotype: protein_coding
description:
  tRNA (adenine-n(1)-)-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.


ensembl_gene_id: VAB18032_22930
symbol: AEB45686.1
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: VAB18032_22945
symbol: mshC
gene_biotype: protein_coding
description:
  cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.


ensembl_gene_id: VAB18032_22970
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: VAB18032_23000
symbol: AEB45700.1
gene_biotype: protein_coding
description:
  Bicupin, oxalate decarboxylase family protein; COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes.


ensembl_gene_id: VAB18032_23020
symbol: AEB45704.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.


ensembl_gene_id: VAB18032_23050
symbol: AEB45710.1
gene_biotype: protein_coding
description:
  ATPase AAA-2 domain-containing protein; COG0542 ATPases with chaperone activity, ATP-binding subunit; Belongs to the ClpA/ClpB family.


ensembl_gene_id: VAB18032_23125
symbol: AEB45725.1
gene_biotype: protein_coding
description:
  Transcriptional regulator domain-containing protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: VAB18032_23160
symbol: secA-2
gene_biotype: protein_coding
description:
  Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: VAB18032_23165
symbol: AEB45733.1
gene_biotype: protein_coding
description:
  Putative glucosyl-3-phosphoglycerate synthase; COG0463 Glycosyltransferases involved in cell wall biogenesis.


ensembl_gene_id: VAB18032_23180
symbol: AEB45736.1
gene_biotype: protein_coding
description:
  COG1191 DNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_23190
symbol: AEB45738.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate central domain-containing protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase].


ensembl_gene_id: VAB18032_23270
symbol: argG
gene_biotype: protein_coding
description:
  COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.


ensembl_gene_id: VAB18032_23285
symbol: AEB45755.1
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase.


ensembl_gene_id: VAB18032_23320
symbol: AEB45762.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase.


ensembl_gene_id: VAB18032_23335
symbol: AEB45765.1
gene_biotype: protein_coding
description:
  Glycogen debranching enzyme glgx; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: VAB18032_23365
symbol: AEB45771.1
gene_biotype: protein_coding
description:
  Sulfatase; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.


ensembl_gene_id: VAB18032_23440
symbol: AEB45786.1
gene_biotype: protein_coding
description:
  Sulfate transporter/antisigma-factor antagonist stas; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: VAB18032_23460
symbol: AEB45790.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG1252 NADH dehydrogenase, FAD-containing subunit.


ensembl_gene_id: VAB18032_23470
symbol: AEB45792.1
gene_biotype: protein_coding
description:
  Oxidoreductase FAD/NAD(P)-binding domain-containing protein; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1.


ensembl_gene_id: VAB18032_23530
symbol: AEB45804.1
gene_biotype: protein_coding
description:
  Protein-tyrosine phosphatase, low molecular weight; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: VAB18032_23540
symbol: nhaA
gene_biotype: protein_coding
description:
  pH-dependent sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: VAB18032_23555
symbol: egtD
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.


ensembl_gene_id: VAB18032_23560
symbol: egtC
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.


ensembl_gene_id: VAB18032_23565
symbol: egtB
gene_biotype: protein_coding
description:
  Hypothetical protein; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.


ensembl_gene_id: VAB18032_23570
symbol: egtA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.


ensembl_gene_id: VAB18032_23590
symbol: AEB45816.1
gene_biotype: protein_coding
description:
  UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: VAB18032_23610
symbol: AEB45820.1
gene_biotype: protein_coding
description:
  Histidine kinase, dimerization and phosphoacceptor region; COG4585 Signal transduction histidine kinase.


ensembl_gene_id: VAB18032_23650
symbol: AEB45828.1
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain-containing protein; COG0513 Superfamily II DNA and RNA helicases; Belongs to the DEAD box helicase family.


ensembl_gene_id: VAB18032_23655
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: VAB18032_23700
symbol: AEB45838.1
gene_biotype: protein_coding
description:
  Transketolase central region; COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit.


ensembl_gene_id: VAB18032_23730
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: VAB18032_23940
symbol: AEB45886.1
gene_biotype: protein_coding
description:
  Glycoside hydrolase family 3 domain-containing protein; COG1472 Beta-glucosidase-related glycosidases.


ensembl_gene_id: VAB18032_24060
symbol: AEB45910.1
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases.


ensembl_gene_id: VAB18032_24090
symbol: AEB45916.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase.


ensembl_gene_id: VAB18032_24095
symbol: AEB45917.1
gene_biotype: protein_coding
description:
  Oligopeptide/dipeptide abc transporter, atpase subunit; COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_24110
symbol: AEB45920.1
gene_biotype: protein_coding
description:
  Family 5 extracellular solute-binding protein; COG0747 ABC-type dipeptide transport system, periplasmic component.


ensembl_gene_id: VAB18032_24120
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: VAB18032_24135
symbol: AEB45925.1
gene_biotype: protein_coding
description:
  Sulfate transporter/antisigma-factor antagonist STAS; COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Belongs to the anti-sigma-factor antagonist family.


ensembl_gene_id: VAB18032_24165
symbol: AEB45931.1
gene_biotype: protein_coding
description:
  Putative short-chain oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).


ensembl_gene_id: VAB18032_24230
symbol: AEB45944.1
gene_biotype: protein_coding
description:
  roadblock/LC7 family protein; COG2018 Uncharacterized distant relative of homeotic protein bithoraxoid.


ensembl_gene_id: VAB18032_24295
symbol: AEB45957.1
gene_biotype: protein_coding
description:
  Ferric uptake regulator, Fur family protein; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family.


ensembl_gene_id: VAB18032_24435
symbol: AEB45985.1
gene_biotype: protein_coding
description:
  Abc transporter integral membrane subunit; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_24485
symbol: AEB45995.1
gene_biotype: protein_coding
description:
  NADPH:quinone reductase-like protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases.


ensembl_gene_id: VAB18032_24505
symbol: AEB45999.1
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: VAB18032_24515
symbol: AEB46001.1
gene_biotype: protein_coding
description:
  FAD-dependent oxidoreductase domain containing 2; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: VAB18032_24540
symbol: AEB46006.1
gene_biotype: protein_coding
description:
  Cupin 2, barrel; COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.


ensembl_gene_id: VAB18032_24610
symbol: AEB46020.1
gene_biotype: protein_coding
description:
  Histidine kinase dimerization and phosphoacceptor region; COG4564 Signal transduction histidine kinase.


ensembl_gene_id: VAB18032_24620
symbol: AEB46022.1
gene_biotype: protein_coding
description:
  ABC transporter-like protein; COG1136 ABC-type antimicrobial peptide transport system, ATPase component.


ensembl_gene_id: VAB18032_24635
symbol: AEB46025.1
gene_biotype: protein_coding
description:
  Alcohol dehydrogenase GroES domain-containing protein; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases.


ensembl_gene_id: VAB18032_24710
symbol: AEB46040.1
gene_biotype: protein_coding
description:
  Glutamine--scyllo-inositol transaminase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: VAB18032_24730
symbol: AEB46044.1
gene_biotype: protein_coding
description:
  Aminotransferase class III; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: VAB18032_24765
symbol: AEB46051.1
gene_biotype: protein_coding
description:
  Daunorubicin resistance ABC transporter ATPase subunit; COG1131 ABC-type multidrug transport system, ATPase component.


ensembl_gene_id: VAB18032_24770
symbol: AEB46052.1
gene_biotype: protein_coding
description:
  Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: VAB18032_24775
symbol: AEB46053.1
gene_biotype: protein_coding
description:
  COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: VAB18032_24785
symbol: AEB46055.1
gene_biotype: protein_coding
description:
  (S)-2-hydroxy-acid oxidase; COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases.


ensembl_gene_id: VAB18032_24815
symbol: AEB46061.1
gene_biotype: protein_coding
description:
  UDP-glucose 6-dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: VAB18032_24880
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl carrier protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: VAB18032_24890
symbol: AEB46076.1
gene_biotype: protein_coding
description:
  Siderophore 2,3-dihydroxybenzoate-glycine-threonine trimeric ester bacillibactin synthetase; COG1020 Non-ribosomal peptide synthetase modules and related proteins.


ensembl_gene_id: VAB18032_25025
symbol: AEB46103.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases.


ensembl_gene_id: VAB18032_25060
symbol: AEB46110.1
gene_biotype: protein_coding
description:
  Transglutaminase domain-containing protein; COG1305 Transglutaminase-like enzymes, putative cysteine proteases.


ensembl_gene_id: VAB18032_25065
symbol: AEB46111.1
gene_biotype: protein_coding
description:
  Luciferase-like, subgroup; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_25160
symbol: AEB46130.1
gene_biotype: protein_coding
description:
  L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: VAB18032_25170
symbol: AEB46132.1
gene_biotype: protein_coding
description:
  Abc transporter related protein; COG3839 ABC-type sugar transport systems, ATPase components; Belongs to the ABC transporter superfamily.


ensembl_gene_id: VAB18032_25320
symbol: AEB46162.1
gene_biotype: protein_coding
description:
  Restriction modification system DNA specificity subunit; COG0732 Restriction endonuclease S subunits.


ensembl_gene_id: VAB18032_25325
symbol: AEB46163.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases.


ensembl_gene_id: VAB18032_25370
symbol: AEB46172.1
gene_biotype: protein_coding
description:
  COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: VAB18032_25420
symbol: AEB46182.1
gene_biotype: protein_coding
description:
  ECF subfamily RNA polymerase sigma-24 factor; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_25425
symbol: AEB46183.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: VAB18032_25490
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; Belongs to the MurCDEF family.


ensembl_gene_id: VAB18032_25510
symbol: AEB46200.1
gene_biotype: protein_coding
description:
  Purine catabolism PurC domain-containing protein; COG2508 Regulator of polyketide synthase expression.


ensembl_gene_id: VAB18032_25530
symbol: kptA
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.


ensembl_gene_id: VAB18032_25535
symbol: AEB46205.1
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: VAB18032_25575
symbol: AEB46213.1
gene_biotype: protein_coding
description:
  Thiamine pyrophosphate protein central region; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Belongs to the TPP enzyme family.


ensembl_gene_id: VAB18032_25635
symbol: AEB46225.1
gene_biotype: protein_coding
description:
  Had-superfamily hydrolase, subfamily iia; COG0647 Predicted sugar phosphatases of the HAD superfamily; Belongs to the HAD-like hydrolase superfamily.


ensembl_gene_id: VAB18032_25640
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: VAB18032_25735
symbol: AEB46245.1
gene_biotype: protein_coding
description:
  Alpha-1,6-glucosidase, pullulanase-type; COG0366 Glycosidases; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: VAB18032_25915
symbol: AEB46281.1
gene_biotype: protein_coding
description:
  NifU family SUF system FeS assembly protein; COG0822 NifU homolog involved in Fe-S cluster formation.


ensembl_gene_id: VAB18032_25920
symbol: AEB46282.1
gene_biotype: protein_coding
description:
  SufS subfamily cysteine desulfurase; COG0520 Selenocysteine lyase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: VAB18032_25925
symbol: AEB46283.1
gene_biotype: protein_coding
description:
  FeS assembly ATPase SufC; COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component.


ensembl_gene_id: VAB18032_25935
symbol: AEB46285.1
gene_biotype: protein_coding
description:
  FeS assembly protein SufD; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: VAB18032_25940
symbol: AEB46286.1
gene_biotype: protein_coding
description:
  FeS assembly protein SufB; COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component.


ensembl_gene_id: VAB18032_25950
symbol: AEB46288.1
gene_biotype: protein_coding
description:
  Cytochrome oxidase assembly; COG1612 Uncharacterized protein required for cytochrome oxidase assembly.


ensembl_gene_id: VAB18032_25965
symbol: ctaB
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: VAB18032_25975
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.


ensembl_gene_id: VAB18032_26000
symbol: rbpA-2
gene_biotype: protein_coding
description:
  Electron transport protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.


ensembl_gene_id: VAB18032_26005
symbol: AEB46299.1
gene_biotype: protein_coding
description:
  Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: VAB18032_26010
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: VAB18032_26020
symbol: AEB46302.1
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase, type i; COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: VAB18032_26025
symbol: whiA
gene_biotype: protein_coding
description:
  Putative sporulation transcription regulator whiA; Involved in cell division and chromosome segregation.


ensembl_gene_id: VAB18032_26030
symbol: AEB46304.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: VAB18032_26080
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease abc, c subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: VAB18032_26095
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: VAB18032_26100
symbol: rsgA-2
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: VAB18032_26145
symbol: AEB46327.1
gene_biotype: protein_coding
description:
  COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains).


ensembl_gene_id: VAB18032_26180
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: VAB18032_26190
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase/protein folding accessory domain-containing protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: VAB18032_26230
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase i; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: VAB18032_26235
symbol: AEB46345.1
gene_biotype: protein_coding
description:
  Phosphate ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.


ensembl_gene_id: VAB18032_26245
symbol: AEB46347.1
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein family 3; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: VAB18032_26280
symbol: AEB46354.1
gene_biotype: protein_coding
description:
  Response regulator receiver/ANTAR domain-containing protein; COG3707 Response regulator with putative antiterminator output domain.


ensembl_gene_id: VAB18032_26290
symbol: AEB46356.1
gene_biotype: protein_coding
description:
  Cys/met metabolism pyridoxal-phosphate-dependent protein; COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases.


ensembl_gene_id: VAB18032_26300
symbol: AEB46358.1
gene_biotype: protein_coding
description:
  Luciferase family oxidoreductase, group 1; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.


ensembl_gene_id: VAB18032_26345
symbol: AEB46367.1
gene_biotype: protein_coding
description:
  Lipase class 2; COG1075 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold.


ensembl_gene_id: VAB18032_26551
symbol: AEB46387.1
gene_biotype: protein_coding
description:
  Glutamate synthase, NADH/nadph, small subunit; COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases.


ensembl_gene_id: VAB18032_26571
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: VAB18032_26576
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: VAB18032_26601
symbol: trpE
gene_biotype: protein_coding
description:
  Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]


ensembl_gene_id: VAB18032_26621
symbol: AEB46399.1
gene_biotype: protein_coding
description:
  Abc drug efflux pump, inner membrane subunit, drrb family protein; COG0842 ABC-type multidrug transport system, permease component.


ensembl_gene_id: VAB18032_26681
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: VAB18032_26696
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: VAB18032_26711
symbol: hisC
gene_biotype: protein_coding
description:
  COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: VAB18032_26716
symbol: hisD
gene_biotype: protein_coding
description:
  Bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: VAB18032_26721
symbol: AEB46417.1
gene_biotype: protein_coding
description:
  Peptidase S16 lon domain-containing protein; COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease.


ensembl_gene_id: VAB18032_26741
symbol: AEB46421.1
gene_biotype: protein_coding
description:
  RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: VAB18032_26746
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: VAB18032_26776
symbol: sepF
gene_biotype: protein_coding
description:
  Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.


ensembl_gene_id: VAB18032_26781
symbol: AEB46429.1
gene_biotype: protein_coding
description:
  Alanine racemase domain-containing protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: VAB18032_26786
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: VAB18032_26791
symbol: ftsQ
gene_biotype: protein_coding
description:
  Polypeptide-transport-associated domain-containing protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.


ensembl_gene_id: VAB18032_26801
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: VAB18032_26811
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: VAB18032_26816
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-d-glutamyl-2, 6-diaminopimelate/d-alanyl-d-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: VAB18032_26821
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: VAB18032_26836
symbol: rsmH
gene_biotype: protein_coding
description:
  16S rRNA m(4)C1402 methyltranserfase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: VAB18032_26841
symbol: mraZ
gene_biotype: protein_coding
description:
  Cell division protein MraZ; COG2001 Uncharacterized protein conserved in bacteria; Belongs to the MraZ family.


ensembl_gene_id: VAB18032_26896
symbol: dinB-2
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: VAB18032_26901
symbol: AEB46453.1
gene_biotype: protein_coding
description:
  Type I phosphodiesterase/nucleotide pyrophosphatase; COG1524 Uncharacterized proteins of the AP superfamily.


ensembl_gene_id: VAB18032_26911
symbol: dnaE2
gene_biotype: protein_coding
description:
  Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: VAB18032_26966
symbol: AEB46466.1
gene_biotype: protein_coding
description:
  COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: VAB18032_26986
symbol: nfo
gene_biotype: protein_coding
description:
  Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: VAB18032_26996
symbol: AEB46472.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family.


ensembl_gene_id: VAB18032_27026
symbol: AEB46478.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.


ensembl_gene_id: VAB18032_27041
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: VAB18032_27046
symbol: pfp
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.


ensembl_gene_id: VAB18032_27051
symbol: AEB46483.1
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase-related fmn-binding protein; COG3871 Uncharacterized stress protein (general stress protein 26).


ensembl_gene_id: VAB18032_27096
symbol: AEB46492.1
gene_biotype: protein_coding
description:
  Fad-dependent pyridine nucleotide-disulfide oxidoreductase; COG2072 Predicted flavoprotein involved in K+ transport.


ensembl_gene_id: VAB18032_27241
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: VAB18032_27251
symbol: AEB46523.1
gene_biotype: protein_coding
description:
  Cytochrome-c oxidase; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.


ensembl_gene_id: VAB18032_27256
symbol: AEB46524.1
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: VAB18032_27261
symbol: AEB46525.1
gene_biotype: protein_coding
description:
  Aminotransferase, class V; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.


ensembl_gene_id: VAB18032_27266
symbol: AEB46526.1
gene_biotype: protein_coding
description:
  SirA family protein; COG0425 Predicted redox protein, regulator of disulfide bond formation; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: VAB18032_27291
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.


ensembl_gene_id: VAB18032_27296
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: VAB18032_27361
symbol: AEB46545.1
gene_biotype: protein_coding
description:
  Cobalbumin biosynthesis protein; COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase.


ensembl_gene_id: VAB18032_27366
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: VAB18032_27381
symbol: pepA
gene_biotype: protein_coding
description:
  Peptidase m17 leucyl aminopeptidase domain protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: VAB18032_27391
symbol: AEB46551.1
gene_biotype: protein_coding
description:
  COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.


ensembl_gene_id: VAB18032_27396
symbol: AEB46552.1
gene_biotype: protein_coding
description:
  COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.


ensembl_gene_id: VAB18032_27431
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: VAB18032_27436
symbol: aspC
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.


ensembl_gene_id: VAB18032_27441
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: VAB18032_27496
symbol: AEB46572.1
gene_biotype: protein_coding
description:
  Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]


ensembl_gene_id: VAB18032_27526
symbol: nadE
gene_biotype: protein_coding
description:
  NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: VAB18032_27531
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: VAB18032_27636
symbol: AEB46600.1
gene_biotype: protein_coding
description:
  Bifunctional DNA primase/polymerase; COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains.


ensembl_gene_id: VAB18032_27651
symbol: AEB46603.1
gene_biotype: protein_coding
description:
  Non-specific serine/threonine protein kinase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family.


ensembl_gene_id: VAB18032_27721
symbol: AEB46617.1
gene_biotype: protein_coding
description:
  Transketolase domain-containing protein; COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.


ensembl_gene_id: VAB18032_27731
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: VAB18032_27761
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: VAB18032_27786
symbol: fabH-2
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase iii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: VAB18032_27796
symbol: AEB46632.1
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: VAB18032_27836
symbol: AEB46640.1
gene_biotype: protein_coding
description:
  Pfkb domain protein; COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB).


ensembl_gene_id: VAB18032_27906
symbol: AEB46654.1
gene_biotype: protein_coding
description:
  Respiratory-chain NADH dehydrogenase domain 51 kda subunit; COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit.


ensembl_gene_id: VAB18032_28081
symbol: AEB46689.1
gene_biotype: protein_coding
description:
  TatD-related deoxyribonuclease; COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold.


ensembl_gene_id: VAB18032_28141
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: VAB18032_28166
symbol: AEB46704.1
gene_biotype: protein_coding
description:
  Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: VAB18032_28191
symbol: AEB46709.1
gene_biotype: protein_coding
description:
  TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.


ensembl_gene_id: VAB18032_28201
symbol: glyQS
gene_biotype: protein_coding
description:
  glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: VAB18032_28291
symbol: AEB46729.1
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: VAB18032_28321
symbol: era
gene_biotype: protein_coding
description:
  GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: VAB18032_28336
symbol: ybeY
gene_biotype: protein_coding
description:
  Metal-binding heat shock protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: VAB18032_28361
symbol: AEB46743.1
gene_biotype: protein_coding
description:
  Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: VAB18032_28366
symbol: dnaJ-2
gene_biotype: protein_coding
description:
  Chaperone protein dnaj; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: VAB18032_28371
symbol: hrcA
gene_biotype: protein_coding
description:
  Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.


ensembl_gene_id: VAB18032_28381
symbol: AEB46747.1
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: VAB18032_28396
symbol: AEB46750.1
gene_biotype: protein_coding
description:
  Phytanoyl-CoA dioxygenase; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.


ensembl_gene_id: VAB18032_28406
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: VAB18032_28436
symbol: AEB46758.1
gene_biotype: protein_coding
description:
  DNA internalization-related competence protein ComEC/Rec2; COG0658 Predicted membrane metal-binding protein.


ensembl_gene_id: VAB18032_28441
symbol: AEB46759.1
gene_biotype: protein_coding
description:
  Helix-hairpin-helix repeat-containing competence protein ComEA; COG1555 DNA uptake protein and related DNA-binding proteins.


ensembl_gene_id: VAB18032_28461
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: VAB18032_28466
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: VAB18032_28501
symbol: obgE
gene_biotype: protein_coding
description:
  GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: VAB18032_28511
symbol: rplU
gene_biotype: protein_coding
description:
  50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: VAB18032_28546
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.


ensembl_gene_id: VAB18032_28551
symbol: AEB46781.1
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein, ahpd family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: VAB18032_28556
symbol: AEB46782.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma subunit, ECF family protein; COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Belongs to the sigma-70 factor family.


ensembl_gene_id: VAB18032_28561
symbol: ndk
gene_biotype: protein_coding
description:
  Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: VAB18032_28581
symbol: valS-2
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: VAB18032_28601
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: VAB18032_28611
symbol: clpP-3
gene_biotype: protein_coding
description:
  Endopeptidase clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: VAB18032_28616
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: VAB18032_28646
symbol: AEB46800.1
gene_biotype: protein_coding
description:
  Carbohydrate ABC transporter; COG1132 ABC-type multidrug transport system, ATPase and permease components.


ensembl_gene_id: VAB18032_28656
symbol: AEB46802.1
gene_biotype: protein_coding
description:
  RimK domain protein ATP-grasp; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase).


ensembl_gene_id: VAB18032_28681
symbol: AEB46807.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG4552 Predicted acetyltransferase involved in intracellular survival and related acetyltransferases.


ensembl_gene_id: VAB18032_28701
symbol: AEB46811.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG2761 Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis.


ensembl_gene_id: VAB18032_28721
symbol: AEB46815.1
gene_biotype: protein_coding
description:
  Amidase; COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Belongs to the amidase family.


ensembl_gene_id: VAB18032_28731
symbol: nbaC
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.


ensembl_gene_id: VAB18032_28766
symbol: kmo
gene_biotype: protein_coding
description:
  Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.


ensembl_gene_id: VAB18032_28771
symbol: kynU
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.


ensembl_gene_id: VAB18032_28776
symbol: kynA
gene_biotype: protein_coding
description:
  Tryptophan 23-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.


ensembl_gene_id: VAB18032_28831
symbol: AEB46837.1
gene_biotype: protein_coding
description:
  Putative ABC transporter ATP-binding protein; COG0488 ATPase components of ABC transporters with duplicated ATPase domains.


ensembl_gene_id: VAB18032_28851
symbol: AEB46841.1
gene_biotype: protein_coding
description:
  uroporphyrin-III C-methyltransferase; COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain).


ensembl_gene_id: VAB18032_28856
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: VAB18032_28861
symbol: AEB46843.1
gene_biotype: protein_coding
description:
  Hypothetical protein; COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase.


ensembl_gene_id: VAB18032_28881
symbol: ligB
gene_biotype: protein_coding
description:
  ATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.


ensembl_gene_id: VAB18032_28906
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: VAB18032_28911
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: VAB18032_28996
symbol: AEB46870.1
gene_biotype: protein_coding
description:
  DnaB domain-containing protein helicase domain-containing protein; COG0305 Replicative DNA helicase.


ensembl_gene_id: VAB18032_29011
symbol: AEB46873.1
gene_biotype: protein_coding
description:
  Putative epoxide hydrolase; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).


ensembl_gene_id: VAB18032_29036
symbol: AEB46878.1
gene_biotype: protein_coding
description:
  MFS transporter multidrug efflux transporter; COG0477 Permeases of the major facilitator superfamily.


ensembl_gene_id: VAB18032_29046
symbol: AEB46880.1
gene_biotype: protein_coding
description:
  Monooxygenase, FAD-binding protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.


ensembl_gene_id: VAB18032_29156
symbol: AEB46902.1
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: VAB18032_29206
symbol: AEB46912.1
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, rpod subfamily protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: VAB18032_29246
symbol: AEB46920.1
gene_biotype: protein_coding
description:
  Tspo and mbr like protein; COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog).


ensembl_gene_id: VAB18032_29396
symbol: AEB46950.1
gene_biotype: protein_coding
description:
  Arginase/agmatinase/formiminoglutamase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.


ensembl_gene_id: VAB18032_29416
symbol: AEB46954.1
gene_biotype: protein_coding
description:
  Lao/ao transport system atpase; COG1703 Putative periplasmic protein kinase ArgK and related GTPases of G3E family.


ensembl_gene_id: VAB18032_29421
symbol: AEB46955.1
gene_biotype: protein_coding
description:
  Putative acyltransferase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: VAB18032_29496
symbol: nucS
gene_biotype: protein_coding
description:
  Hypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.


ensembl_gene_id: VAB18032_29571
symbol: atpC
gene_biotype: protein_coding
description:
  H+-transporting two-sector ATPase, delta/epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: VAB18032_29581
symbol: atpD
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: VAB18032_29586
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase f1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: VAB18032_29591
symbol: atpA
gene_biotype: protein_coding
description:
  F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: VAB18032_29596
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase f1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: VAB18032_29601
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: VAB18032_29606
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: VAB18032_29611
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: VAB18032_29626
symbol: glyA-2
gene_biotype: protein_coding
description:
  Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: VAB18032_29651
symbol: prmC
gene_biotype: protein_coding
description:
  N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: VAB18032_29661
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: VAB18032_29671
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: VAB18032_29676
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: VAB18032_29686
symbol: AEB47008.1
gene_biotype: protein_coding
description:
  Acriflavin resistance protein; COG0841 Cation/multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: VAB18032_29696
symbol: AEB47010.1
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: VAB18032_29706
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: VAB18032_29821
symbol: AEB47035.1
gene_biotype: protein_coding
description:
  Cellulose-binding family II protein; COG3469 Chitinase; Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: VAB18032_29831
symbol: AEB47037.1
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase gcs2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.


ensembl_gene_id: VAB18032_29836
symbol: AEB47038.1
gene_biotype: protein_coding
description:
  FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.


ensembl_gene_id: VAB18032_29846
symbol: AEB47040.1
gene_biotype: protein_coding
description:
  DNA glycosylase/ap lyase, h2th DNA-binding protein; COG0266 Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family.


ensembl_gene_id: VAB18032_29851
symbol: AEB47041.1
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase SDR; COG0300 Short-chain dehydrogenases of various substrate specificities.


ensembl_gene_id: VAB18032_29961
symbol: kgd
gene_biotype: protein_coding
description:
  Alpha-ketoglutarate decarboxylase; COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes.


ensembl_gene_id: VAB18032_29971
symbol: AEB47065.1
gene_biotype: protein_coding
description:
  Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: VAB18032_29976
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: VAB18032_30041
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: VAB18032_30051
symbol: AEB47081.1
gene_biotype: protein_coding
description:
  COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: VAB18032_30066
symbol: AEB47084.1
gene_biotype: protein_coding
description:
  Glutamine--fructose-6-phosphate transaminase (isomerizing); COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains.


