# geneInfo

ensembl_gene_id: A0A0N4XC50
symbol: NBR_LOCUS6
gene_biotype: protein_coding
description:
  Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family.


ensembl_gene_id: A0A0N4XC83
symbol: NBR_LOCUS45
gene_biotype: protein_coding
description:
  FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]


ensembl_gene_id: A0A0N4XC87
symbol: NBR_LOCUS49
gene_biotype: protein_coding
description:
  Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]


ensembl_gene_id: A0A0N4XC90
symbol: NBR_LOCUS52
gene_biotype: protein_coding
description:
  LD36273p (inferred by orthology to a D. melanogaster protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4XCB0
symbol: NBR_LOCUS76
gene_biotype: protein_coding
description:
  O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis.


ensembl_gene_id: A0A0N4XCC6
symbol: NBR_LOCUS94
gene_biotype: protein_coding
description:
  FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.


ensembl_gene_id: A0A0N4XCD6
symbol: NBR_LOCUS107
gene_biotype: protein_coding
description:
  Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A0N4XCG7
symbol: NBR_LOCUS143
gene_biotype: protein_coding
description:
  Probable endochitinase (inferred by orthology to a C. elegans protein); Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: A0A0N4XCH3
symbol: NBR_LOCUS150
gene_biotype: protein_coding
description:
  Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: A0A0N4XCK6
symbol: NBR_LOCUS189
gene_biotype: protein_coding
description:
  GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.


ensembl_gene_id: A0A0N4XCN7
symbol: NBR_LOCUS231
gene_biotype: protein_coding
description:
  Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.


ensembl_gene_id: A0A0N4XCQ0
symbol: MCM7
gene_biotype: protein_coding
description:
  DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]


ensembl_gene_id: A0A0N4XCS4
symbol: NBR_LOCUS274
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase Genghis Khan (inferred by orthology to a D. melanogaster protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XCV0
symbol: NBR_LOCUS304
gene_biotype: protein_coding
description:
  2-hydroxyacyl-CoA lyase 1 (inferred by orthology to a human protein); Belongs to the TPP enzyme family.


ensembl_gene_id: A0A0N4XCZ2
symbol: NBR_LOCUS349
gene_biotype: protein_coding
description:
  High-affinity choline transporter 1 (inferred by orthology to a C. elegans protein); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A0N4XCZ9
symbol: NBR_LOCUS358
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A0N4XD13
symbol: NBR_LOCUS374
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 K (inferred by orthology to a human protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A0N4XD64
symbol: NBR_LOCUS439
gene_biotype: protein_coding
description:
  Ubiquitin-like modifier-activating enzyme 6 (inferred by orthology to a human protein); Belongs to the ubiquitin-activating E1 family.


ensembl_gene_id: A0A0N4XD86
symbol: NBR_LOCUS470
gene_biotype: protein_coding
description:
  Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.


ensembl_gene_id: A0A0N4XD93
symbol: NBR_LOCUS477
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase 7 (inferred by orthology to a C. elegans protein); Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A0N4XDA9
symbol: NBR_LOCUS495
gene_biotype: protein_coding
description:
  Dual specificity protein kinase TTK (inferred by orthology to a human protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XDD2
symbol: NBR_LOCUS519
gene_biotype: protein_coding
description:
  Cyclin-dependent kinase 1 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XDD4
symbol: NBR_LOCUS521
gene_biotype: protein_coding
description:
  Cytochrome P450 4V2 (inferred by orthology to a human protein); Belongs to the cytochrome P450 family.


ensembl_gene_id: A0A0N4XDE2
symbol: NBR_LOCUS534
gene_biotype: protein_coding
description:
  Tyrosine-protein kinase transmembrane receptor (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A0N4XDE4
symbol: NBR_LOCUS537
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase SDR family member 13 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4XDE8
symbol: NBR_LOCUS542
gene_biotype: protein_coding
description:
  NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.


ensembl_gene_id: A0A0N4XDH6
symbol: NBR_LOCUS576
gene_biotype: protein_coding
description:
  Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.


ensembl_gene_id: A0A0N4XDJ4
symbol: NBR_LOCUS594
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


ensembl_gene_id: A0A0N4XDK1
symbol: NBR_LOCUS602
gene_biotype: protein_coding
description:
  ATP synthase lipid-binding protein, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the ATPase C chain family.


ensembl_gene_id: A0A0N4XDK5
symbol: NBR_LOCUS606
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.


ensembl_gene_id: A0A0N4XDK8
symbol: NBR_LOCUS610
gene_biotype: protein_coding
description:
  H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine (psi) residues may serve to stabilize the conformation of rRNAs.


ensembl_gene_id: A0A0N4XDL0
symbol: NBR_LOCUS612
gene_biotype: protein_coding
description:
  Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.


ensembl_gene_id: A0A0N4XDL1
symbol: NBR_LOCUS613
gene_biotype: protein_coding
description:
  60S ribosomal protein L11 (inferred by orthology to a human protein); Belongs to the universal ribosomal protein uL5 family.


ensembl_gene_id: A0A0N4XDP1
symbol: NBR_LOCUS644
gene_biotype: protein_coding
description:
  Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.


ensembl_gene_id: A0A0N4XDP3
symbol: NBR_LOCUS646
gene_biotype: protein_coding
description:
  28S ribosomal protein S12, mitochondrial (inferred by orthology to a human protein); Belongs to the universal ribosomal protein uS12 family.


ensembl_gene_id: A0A0N4XDS5
symbol: NBR_LOCUS678
gene_biotype: protein_coding
description:
  Acetylcholine receptor subunit beta-type lev-1 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4XDU3
symbol: NBR_LOCUS696
gene_biotype: protein_coding
description:
  Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).


ensembl_gene_id: A0A0N4XDW7
symbol: NBR_LOCUS720
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: A0A0N4XDX5
symbol: NBR_LOCUS728
gene_biotype: protein_coding
description:
  Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.


ensembl_gene_id: A0A0N4XDZ3
symbol: NBR_LOCUS746
gene_biotype: protein_coding
description:
  Uncharacterized mitochondrial carrier (inferred by orthology to a C. elegans protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4XDZ4
symbol: NBR_LOCUS747
gene_biotype: protein_coding
description:
  Leucine--tRNA ligase (inferred by orthology to a C. elegans protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4XE23
symbol: NBR_LOCUS776
gene_biotype: protein_coding
description:
  Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A0N4XE37
symbol: NBR_LOCUS790
gene_biotype: protein_coding
description:
  Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.


ensembl_gene_id: A0A0N4XE53
symbol: NBR_LOCUS806
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily F member 1 (inferred by orthology to a human protein); Belongs to the potassium channel family.


ensembl_gene_id: A0A0N4XE83
symbol: NBR_LOCUS836
gene_biotype: protein_coding
description:
  Probable leucine--tRNA ligase, mitochondrial (inferred by orthology to a human protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4XE84
symbol: NBR_LOCUS837
gene_biotype: protein_coding
description:
  ADP-ribosylation factor 1-like 2 (inferred by orthology to a C. elegans protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4XEA7
symbol: NBR_LOCUS860
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase 24 (inferred by orthology to a human protein); Belongs to the peptidase C19 family.


ensembl_gene_id: A0A0N4XEB6
symbol: NBR_LOCUS869
gene_biotype: protein_coding
description:
  Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.


ensembl_gene_id: A0A0N4XED1
symbol: NBR_LOCUS884
gene_biotype: protein_coding
description:
  RRM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.


ensembl_gene_id: A0A0N4XEG5
symbol: NBR_LOCUS918
gene_biotype: protein_coding
description:
  Phosphatidylinositol 4-kinase alpha (inferred by orthology to a human protein); Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A0N4XEK0
symbol: NBR_LOCUS953
gene_biotype: protein_coding
description:
  Soluble guanylate cyclase gcy-35 (inferred by orthology to a C. elegans protein); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A0N4XEN8
symbol: NBR_LOCUS991
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel subfamily KQT member 1 (inferred by orthology to a human protein); Belongs to the potassium channel family.


ensembl_gene_id: A0A0N4XEP4
symbol: NBR_LOCUS997
gene_biotype: protein_coding
description:
  Maleylacetoacetate isomerase (inferred by orthology to a human protein); Belongs to the GST superfamily.


ensembl_gene_id: A0A0N4XEP9
symbol: NBR_LOCUS1002
gene_biotype: protein_coding
description:
  Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.


ensembl_gene_id: A0A0N4XEQ1
symbol: NBR_LOCUS1004
gene_biotype: protein_coding
description:
  Guanylate cyclase (inferred by orthology to a C. elegans protein); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A0N4XEQ4
symbol: NBR_LOCUS1007
gene_biotype: protein_coding
description:
  Latrophilin-like protein 1 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 2 family.


ensembl_gene_id: A0A0N4XEQ9
symbol: MED18
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4XES0
symbol: NBR_LOCUS1023
gene_biotype: protein_coding
description:
  GluClalpha (inferred by orthology to a D. melanogaster protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4XET7
symbol: NBR_LOCUS1040
gene_biotype: protein_coding
description:
  Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.


ensembl_gene_id: A0A0N4XEW5
symbol: NBR_LOCUS1068
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.


ensembl_gene_id: A0A0N4XEZ4
symbol: NBR_LOCUS1097
gene_biotype: protein_coding
description:
  S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.


ensembl_gene_id: A0A0N4XEZ6
symbol: NBR_LOCUS1099
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase (inferred by orthology to a C. elegans protein); Belongs to the peptidase C19 family.


ensembl_gene_id: A0A0N4XF02
symbol: NBR_LOCUS1105
gene_biotype: protein_coding
description:
  Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: A0A0N4XF29
symbol: NBR_LOCUS1132
gene_biotype: protein_coding
description:
  F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.


ensembl_gene_id: A0A0N4XF69
symbol: NBR_LOCUS1172
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.


ensembl_gene_id: A0A0N4XF71
symbol: NBR_LOCUS1174
gene_biotype: protein_coding
description:
  GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.


ensembl_gene_id: A0A0N4XF73
symbol: NBR_LOCUS1176
gene_biotype: protein_coding
description:
  Mitotic checkpoint serine/threonine-protein kinase BUB1 (inferred by orthology to a human protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XF83
symbol: NBR_LOCUS1186
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A0N4XF90
symbol: NBR_LOCUS1194
gene_biotype: protein_coding
description:
  60S ribosomal protein L12 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uL11 family.


ensembl_gene_id: A0A0N4XFB0
symbol: NBR_LOCUS1213
gene_biotype: protein_coding
description:
  Fidgetin-like protein 1 (inferred by orthology to a C. elegans protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4XFB1
symbol: NBR_LOCUS1214
gene_biotype: protein_coding
description:
  Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.


ensembl_gene_id: A0A0N4XFB6
symbol: NBR_LOCUS1219
gene_biotype: protein_coding
description:
  Probable 3',5'-cyclic phosphodiesterase pde-3 (inferred by orthology to a C. elegans protein); Belongs to the cyclic nucleotide phosphodiesterase family.


ensembl_gene_id: A0A0N4XFG8
symbol: NBR_LOCUS1271
gene_biotype: protein_coding
description:
  Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.


ensembl_gene_id: A0A0N4XFH5
symbol: NBR_LOCUS1278
gene_biotype: protein_coding
description:
  Isoleucine--tRNA ligase, cytoplasmic (inferred by orthology to a human protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4XFK5
symbol: NBR_LOCUS1308
gene_biotype: protein_coding
description:
  S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.


ensembl_gene_id: A0A0N4XFM3
symbol: NBR_LOCUS1326
gene_biotype: protein_coding
description:
  Putative sodium-coupled neutral amino acid transporter 9 (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4XFN5
symbol: NBR_LOCUS1338
gene_biotype: protein_coding
description:
  Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.


ensembl_gene_id: A0A0N4XFN6
symbol: NBR_LOCUS1339
gene_biotype: protein_coding
description:
  Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.


ensembl_gene_id: A0A0N4XFN8
symbol: NBR_LOCUS1341
gene_biotype: protein_coding
description:
  TWiK family of potassium channels protein 7 (inferred by orthology to a C. elegans protein); Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A0N4XFR0
symbol: NBR_LOCUS1363
gene_biotype: protein_coding
description:
  EKC/KEOPS complex subunit TPRKB (inferred by orthology to a human protein); Belongs to the CGI121/TPRKB family.


ensembl_gene_id: A0A0N4XFS6
symbol: NBR_LOCUS1379
gene_biotype: protein_coding
description:
  Mitochondrial uncoupling protein 4 (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4XFZ3
symbol: NBR_LOCUS1446
gene_biotype: protein_coding
description:
  DNA replication licensing factor MCM2 (inferred by orthology to a human protein); Belongs to the MCM family.


ensembl_gene_id: A0A0N4XFZ6
symbol: NBR_LOCUS1451
gene_biotype: protein_coding
description:
  Dual specificity protein phosphatase 19 (inferred by orthology to a human protein); Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.


ensembl_gene_id: A0A0N4XFZ7
symbol: NBR_LOCUS1452
gene_biotype: protein_coding
description:
  Valine--tRNA ligase, mitochondrial (inferred by orthology to a human protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4XG29
symbol: NBR_LOCUS1484
gene_biotype: protein_coding
description:
  Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A0N4XG38
symbol: NBR_LOCUS1490
gene_biotype: protein_coding
description:
  Multiple exostoses homolog 1 (inferred by orthology to a C. elegans protein); Belongs to the glycosyltransferase 47 family.


ensembl_gene_id: A0A0N4XG53
symbol: NBR_LOCUS1506
gene_biotype: protein_coding
description:
  Glutamine synthetase (inferred by orthology to a human protein); Belongs to the glutamine synthetase family.


ensembl_gene_id: A0A0N4XG72
symbol: NBR_LOCUS1525
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 33A (inferred by orthology to a C. elegans protein); Belongs to the STXBP/unc-18/SEC1 family.


ensembl_gene_id: A0A0N4XGB7
symbol: NBR_LOCUS1573
gene_biotype: protein_coding
description:
  Ligand-gated ion channel 50 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4XGC5
symbol: NBR_LOCUS1580
gene_biotype: protein_coding
description:
  Probable 26S protease regulatory subunit 10B (inferred by orthology to a C. elegans protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4XGD1
symbol: NBR_LOCUS1584
gene_biotype: protein_coding
description:
  Lysosomal protective protein (inferred by orthology to a human protein); Belongs to the peptidase S10 family.


ensembl_gene_id: A0A0N4XGH7
symbol: NBR_LOCUS1630
gene_biotype: protein_coding
description:
  Dynamin-like 120 kDa protein, mitochondrial (inferred by orthology to a human protein); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A0N4XGL7
symbol: NBR_LOCUS1670
gene_biotype: protein_coding
description:
  DNA replication licensing factor mcm-5 (inferred by orthology to a C. elegans protein); Belongs to the MCM family.


ensembl_gene_id: A0A0N4XGM2
symbol: NBR_LOCUS1675
gene_biotype: protein_coding
description:
  AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.


ensembl_gene_id: A0A0N4XGM4
symbol: NBR_LOCUS1677
gene_biotype: protein_coding
description:
  Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.


ensembl_gene_id: A0A0N4XGP4
symbol: NBR_LOCUS1697
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4XGQ6
symbol: NBR_LOCUS1709
gene_biotype: protein_coding
description:
  Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A0N4XGU1
symbol: NBR_LOCUS1744
gene_biotype: protein_coding
description:
  Probable ribosome biogenesis protein NBR_LOCUS1744; Probable pre-rRNA processing protein involved in ribosome biogenesis.


ensembl_gene_id: A0A0N4XGU5
symbol: NBR_LOCUS1748
gene_biotype: protein_coding
description:
  40S ribosomal protein S14 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: A0A0N4XGV3
symbol: NBR_LOCUS1756
gene_biotype: protein_coding
description:
  Protein sly1 homolog (inferred by orthology to a D. melanogaster protein); Belongs to the STXBP/unc-18/SEC1 family.


ensembl_gene_id: A0A0N4XGX6
symbol: NBR_LOCUS1779
gene_biotype: protein_coding
description:
  Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.


ensembl_gene_id: A0A0N4XGY0
symbol: NBR_LOCUS1784
gene_biotype: protein_coding
description:
  Double-strand break repair protein mre-11 (inferred by orthology to a C. elegans protein); Belongs to the MRE11/RAD32 family.


ensembl_gene_id: A0A0N4XGY2
symbol: NBR_LOCUS1785
gene_biotype: protein_coding
description:
  TWiK family of potassium channels protein 9 (inferred by orthology to a C. elegans protein); Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A0N4XGZ5
symbol: NBR_LOCUS1798
gene_biotype: protein_coding
description:
  ADP-ribosylation factor-like protein 3 (inferred by orthology to a C. elegans protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4XH10
symbol: NBR_LOCUS1813
gene_biotype: protein_coding
description:
  GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.


ensembl_gene_id: A0A0N4XH39
symbol: NBR_LOCUS1842
gene_biotype: protein_coding
description:
  Guanosine-diphosphatase, putative (inferred by orthology to a S. mansoni protein); Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A0N4XH79
symbol: NBR_LOCUS1882
gene_biotype: protein_coding
description:
  CSK-1 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A0N4XHB5
symbol: NBR_LOCUS1918
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 H (inferred by orthology to a human protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A0N4XHD0
symbol: NBR_LOCUS1933
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase par-1 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XHD3
symbol: NBR_LOCUS1936
gene_biotype: protein_coding
description:
  Glutamate receptor 2 (inferred by orthology to a C. elegans protein); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.


ensembl_gene_id: A0A0N4XHF5
symbol: NBR_LOCUS1958
gene_biotype: protein_coding
description:
  Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.


ensembl_gene_id: A0A0N4XHJ7
symbol: NBR_LOCUS2000
gene_biotype: protein_coding
description:
  JYalpha (inferred by orthology to a D. melanogaster protein); Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A0N4XHT7
symbol: NBR_LOCUS2090
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger 6, mitochondrial (inferred by orthology to a human protein); Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A0N4XI00
symbol: NBR_LOCUS2153
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: A0A0N4XIE4
symbol: MED4
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4XIE7
symbol: NBR_LOCUS2300
gene_biotype: protein_coding
description:
  Neur_chan_memb domain-containing protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4XIV5
symbol: LSM1
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm1; Probably involved with other LSm subunits in the general process of degradation of mRNAs.


ensembl_gene_id: A0A0N4XIW7
symbol: NBR_LOCUS2469
gene_biotype: protein_coding
description:
  Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.


ensembl_gene_id: A0A0N4XIZ5
symbol: NBR_LOCUS2497
gene_biotype: protein_coding
description:
  Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: A0A0N4XJA3
symbol: NBR_LOCUS2606
gene_biotype: protein_coding
description:
  PAB-dependent poly(A)-specific ribonuclease subunit PAN2 (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4XJC1
symbol: NBR_LOCUS2624
gene_biotype: protein_coding
description:
  Acetyl-CoA acetyltransferase, mitochondrial (inferred by orthology to a human protein); Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A0N4XJD2
symbol: NBR_LOCUS2635
gene_biotype: protein_coding
description:
  Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.


ensembl_gene_id: A0A0N4XJF1
symbol: NBR_LOCUS2652
gene_biotype: protein_coding
description:
  Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.


ensembl_gene_id: A0A0N4XJF7
symbol: NBR_LOCUS2660
gene_biotype: protein_coding
description:
  Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.


ensembl_gene_id: A0A0N4XJF8
symbol: NBR_LOCUS2661
gene_biotype: protein_coding
description:
  Putative structural maintenance of chromosomes smc3 (inferred by orthology to a S. mansoni protein).


ensembl_gene_id: A0A0N4XJJ9
symbol: NBR_LOCUS2702
gene_biotype: protein_coding
description:
  60S ribosomal protein L13a (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uL13 family.


ensembl_gene_id: A0A0N4XJL9
symbol: NBR_LOCUS2723
gene_biotype: protein_coding
description:
  Degenerin-like protein asic-1 (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A0N4XJN0
symbol: NBR_LOCUS2733
gene_biotype: protein_coding
description:
  Cytochrome c 2.1 (inferred by orthology to a C. elegans protein); Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.


ensembl_gene_id: A0A0N4XK11
symbol: NBR_LOCUS2864
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit 1, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the peptidase M16 family.


ensembl_gene_id: A0A0N4XKC0
symbol: NBR_LOCUS2972
gene_biotype: protein_coding
description:
  Cell division control protein 2 cognate (inferred by orthology to a D. melanogaster protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XKC7
symbol: NBR_LOCUS2980
gene_biotype: protein_coding
description:
  Potassium voltage-gated channel protein shk-1 (inferred by orthology to a C. elegans protein); Belongs to the potassium channel family.


ensembl_gene_id: A0A0N4XKG4
symbol: NBR_LOCUS3017
gene_biotype: protein_coding
description:
  T-complex protein 1 subunit zeta (inferred by orthology to a C. elegans protein); Belongs to the TCP-1 chaperonin family.


ensembl_gene_id: A0A0N4XKM3
symbol: NBR_LOCUS3076
gene_biotype: protein_coding
description:
  5-methylcytosine rRNA methyltransferase NSUN4 (inferred by orthology to a human protein); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A0N4XKP6
symbol: NBR_LOCUS3100
gene_biotype: protein_coding
description:
  Phosphate carrier protein, mitochondrial (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4XKQ0
symbol: NBR_LOCUS3102
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.


ensembl_gene_id: A0A0N4XKR0
symbol: NBR_LOCUS3113
gene_biotype: protein_coding
description:
  Lysophospholipid acyltransferase 5 (inferred by orthology to a C. elegans protein); Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A0N4XL09
symbol: NBR_LOCUS3212
gene_biotype: protein_coding
description:
  Probable ribosome biogenesis protein NBR_LOCUS3212; Probable pre-rRNA processing protein involved in ribosome biogenesis.


ensembl_gene_id: A0A0N4XLD7
symbol: NBR_LOCUS3340
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.


ensembl_gene_id: A0A0N4XLJ0
symbol: NBR_LOCUS3393
gene_biotype: protein_coding
description:
  tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family.


ensembl_gene_id: A0A0N4XLP8
symbol: NBR_LOCUS3451
gene_biotype: protein_coding
description:
  Cyclin-dependent kinase 8 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XLQ9
symbol: NBR_LOCUS3462
gene_biotype: protein_coding
description:
  Tricarboxylate transport protein, mitochondrial (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4XLY2
symbol: NBR_LOCUS3535
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase spk-1 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XM32
symbol: NBR_LOCUS3585
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]


ensembl_gene_id: A0A0N4XMF5
symbol: NBR_LOCUS3708
gene_biotype: protein_coding
description:
  Putative glutamyl-tRNA synthetase, cytoplasmic (inferred by orthology to a S. mansoni protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4XML9
symbol: NBR_LOCUS3772
gene_biotype: protein_coding
description:
  Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family.


ensembl_gene_id: A0A0N4XMN0
symbol: NBR_LOCUS3783
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.


ensembl_gene_id: A0A0N4XMW7
symbol: NBR_LOCUS3871
gene_biotype: protein_coding
description:
  Probable 39S ribosomal protein L11, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uL11 family.


ensembl_gene_id: A0A0N4XN83
symbol: NBR_LOCUS3986
gene_biotype: protein_coding
description:
  AP-1 complex subunit mu-1-I (inferred by orthology to a C. elegans protein); Belongs to the adaptor complexes medium subunit family.


ensembl_gene_id: A0A0N4XNH2
symbol: NBR_LOCUS4077
gene_biotype: protein_coding
description:
  Probable signal recognition particle 19 kDa protein (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4XNY8
symbol: NBR_LOCUS4241
gene_biotype: protein_coding
description:
  Transcription elongation factor B polypeptide 1 (inferred by orthology to a human protein); Belongs to the SKP1 family.


ensembl_gene_id: A0A0N4XNZ7
symbol: NBR_LOCUS4249
gene_biotype: protein_coding
description:
  Heat-stable enterotoxin receptor (inferred by orthology to a human protein); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A0N4XP22
symbol: NBR_LOCUS4275
gene_biotype: protein_coding
description:
  60S ribosomal protein L38 (inferred by orthology to a C. elegans protein); Belongs to the eukaryotic ribosomal protein eL38 family.


ensembl_gene_id: A0A0N4XQ04
symbol: NBR_LOCUS4605
gene_biotype: protein_coding
description:
  Dynamin (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A0N4XQC7
symbol: NBR_LOCUS4730
gene_biotype: protein_coding
description:
  Putative cys-loop ligand gated ion channel subunit (inferred by orthology to a S. mansoni protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4XQT1
symbol: NBR_LOCUS4884
gene_biotype: protein_coding
description:
  Protein-cysteine N-palmitoyltransferase HHAT (inferred by orthology to a human protein); Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A0N4XR38
symbol: NBR_LOCUS4991
gene_biotype: protein_coding
description:
  Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.


ensembl_gene_id: A0A0N4XRB9
symbol: NBR_LOCUS5071
gene_biotype: protein_coding
description:
  V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A0N4XRM1
symbol: NBR_LOCUS5174
gene_biotype: protein_coding
description:
  Phorbol ester/diacylglycerol-binding protein unc-13 (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4XS48
symbol: NBR_LOCUS5352
gene_biotype: protein_coding
description:
  Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family.


ensembl_gene_id: A0A0N4XSD3
symbol: NBR_LOCUS5436
gene_biotype: protein_coding
description:
  40S ribosomal protein SA (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: A0A0N4XSW5
symbol: NBR_LOCUS5620
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]


ensembl_gene_id: A0A0N4XSX6
symbol: NBR_LOCUS5632
gene_biotype: protein_coding
description:
  Potassium channel subfamily K member 18 (inferred by orthology to a human protein); Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A0N4XSZ0
symbol: NBR_LOCUS5656
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 4E-4 (inferred by orthology to a C. elegans protein); Belongs to the eukaryotic initiation factor 4E family.


ensembl_gene_id: A0A0N4XT51
symbol: NBR_LOCUS5745
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.


ensembl_gene_id: A0A0N4XT53
symbol: NBR_LOCUS5747
gene_biotype: protein_coding
description:
  Globin-like protein 26 (inferred by orthology to a C. elegans protein); Belongs to the globin family.


ensembl_gene_id: A0A0N4XT74
symbol: NBR_LOCUS5776
gene_biotype: protein_coding
description:
  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.


ensembl_gene_id: A0A0N4XT77
symbol: NBR_LOCUS5780
gene_biotype: protein_coding
description:
  Adenylate cyclase type 3 (inferred by orthology to a human protein); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A0N4XTD1
symbol: NBR_LOCUS5849
gene_biotype: protein_coding
description:
  Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.


ensembl_gene_id: A0A0N4XTD6
symbol: NBR_LOCUS5856
gene_biotype: protein_coding
description:
  Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.


ensembl_gene_id: A0A0N4XTE6
symbol: NBR_LOCUS5867
gene_biotype: protein_coding
description:
  40S ribosomal protein S5 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: A0A0N4XTE7
symbol: NBR_LOCUS5868
gene_biotype: protein_coding
description:
  Probable protein disulfide-isomerase A6 (inferred by orthology to a C. elegans protein); Belongs to the protein disulfide isomerase family.


ensembl_gene_id: A0A0N4XTG8
symbol: NBR_LOCUS5895
gene_biotype: protein_coding
description:
  Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.


ensembl_gene_id: A0A0N4XTH6
symbol: NBR_LOCUS5906
gene_biotype: protein_coding
description:
  Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.


ensembl_gene_id: A0A0N4XTS9
symbol: NBR_LOCUS6039
gene_biotype: protein_coding
description:
  Tyrosine kinase (inferred by orthology to a S. mansoni protein); Belongs to the protein kinase superfamily. Tyr protein kinase family.


ensembl_gene_id: A0A0N4XTV1
symbol: NBR_LOCUS6067
gene_biotype: protein_coding
description:
  Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.


ensembl_gene_id: A0A0N4XTW2
symbol: NBR_LOCUS6084
gene_biotype: protein_coding
description:
  Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family.


ensembl_gene_id: A0A0N4XTW5
symbol: NBR_LOCUS6090
gene_biotype: protein_coding
description:
  60S ribosomal protein L44 (inferred by orthology to a C. elegans protein); Belongs to the eukaryotic ribosomal protein eL42 family.


ensembl_gene_id: A0A0N4XTX0
symbol: NBR_LOCUS6097
gene_biotype: protein_coding
description:
  Mitochondrial import receptor subunit TOM40 homolog (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4XTX8
symbol: NBR_LOCUS6107
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A0N4XTY7
symbol: NBR_LOCUS6118
gene_biotype: protein_coding
description:
  Probable glutamate--tRNA ligase, mitochondrial (inferred by orthology to a human protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4XTY9
symbol: NBR_LOCUS6120
gene_biotype: protein_coding
description:
  Estradiol 17-beta-dehydrogenase 12 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4XU45
symbol: NBR_LOCUS6200
gene_biotype: protein_coding
description:
  Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.


ensembl_gene_id: A0A0N4XU52
symbol: NBR_LOCUS6211
gene_biotype: protein_coding
description:
  tRNA (cytosine(38)-C(5))-methyltransferase (inferred by orthology to a human protein); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: A0A0N4XU57
symbol: NBR_LOCUS6219
gene_biotype: protein_coding
description:
  Probable spastin homolog spas-1 (inferred by orthology to a C. elegans protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4XU72
symbol: NBR_LOCUS6237
gene_biotype: protein_coding
description:
  Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.


ensembl_gene_id: A0A0N4XU88
symbol: NBR_LOCUS6258
gene_biotype: protein_coding
description:
  Facilitated glucose transporter protein 1 (inferred by orthology to a C. elegans protein); Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A0N4XUC5
symbol: NBR_LOCUS6303
gene_biotype: protein_coding
description:
  Myosin-1 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A0N4XUC6
symbol: NBR_LOCUS6304
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A0N4XUH2
symbol: NBR_LOCUS6361
gene_biotype: protein_coding
description:
  Putative mitochondrial glutamate carrier protein (inferred by orthology to a S. mansoni protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4XUJ0
symbol: NBR_LOCUS6384
gene_biotype: protein_coding
description:
  Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. Belongs to the adenylate kinase family. AK6 subfamily.


ensembl_gene_id: A0A0N4XUK1
symbol: NBR_LOCUS6397
gene_biotype: protein_coding
description:
  Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.


ensembl_gene_id: A0A0N4XUL5
symbol: NBR_LOCUS6414
gene_biotype: protein_coding
description:
  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors  [...]


ensembl_gene_id: A0A0N4XUM1
symbol: NBR_LOCUS6422
gene_biotype: protein_coding
description:
  Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.


ensembl_gene_id: A0A0N4XUQ4
symbol: NBR_LOCUS6461
gene_biotype: protein_coding
description:
  Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: A0A0N4XUS4
symbol: NBR_LOCUS6482
gene_biotype: protein_coding
description:
  Protein phosphatase 1 regulatory subunit 37 homolog (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4XUW9
symbol: NBR_LOCUS6538
gene_biotype: protein_coding
description:
  rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.


ensembl_gene_id: A0A0N4XUX1
symbol: NBR_LOCUS6544
gene_biotype: protein_coding
description:
  Unconventional myosin heavy chain 6 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A0N4XV11
symbol: NBR_LOCUS6594
gene_biotype: protein_coding
description:
  ADP-ribosylation factor-like protein 8B (inferred by orthology to a human protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4XV21
symbol: NBR_LOCUS6606
gene_biotype: protein_coding
description:
  Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.


ensembl_gene_id: A0A0N4XV48
symbol: NBR_LOCUS6642
gene_biotype: protein_coding
description:
  Putative alpha-L-fucosidase (inferred by orthology to a C. elegans protein); Belongs to the glycosyl hydrolase 29 family.


ensembl_gene_id: A0A0N4XV79
symbol: NBR_LOCUS6682
gene_biotype: protein_coding
description:
  Putative chitinase (inferred by orthology to a S. mansoni protein); Belongs to the glycosyl hydrolase 18 family.


ensembl_gene_id: A0A0N4XVA1
symbol: NBR_LOCUS6707
gene_biotype: protein_coding
description:
  Tyramine receptor Ser-2 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4XVA6
symbol: NBR_LOCUS6712
gene_biotype: protein_coding
description:
  14-3-3-like protein 2 (inferred by orthology to a C. elegans protein); Belongs to the 14-3-3 family.


ensembl_gene_id: A0A0N4XVB0
symbol: NBR_LOCUS6717
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.


ensembl_gene_id: A0A0N4XVB2
symbol: NBR_LOCUS6719
gene_biotype: protein_coding
description:
  Valine--tRNA ligase (inferred by orthology to a C. elegans protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4XVF1
symbol: NBR_LOCUS6776
gene_biotype: protein_coding
description:
  Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.


ensembl_gene_id: A0A0N4XVG0
symbol: NBR_LOCUS6786
gene_biotype: protein_coding
description:
  MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A0N4XVN4
symbol: NBR_LOCUS6875
gene_biotype: protein_coding
description:
  78 kDa glucose-regulated protein (inferred by orthology to a human protein); Belongs to the heat shock protein 70 family.


ensembl_gene_id: A0A0N4XVQ7
symbol: NBR_LOCUS6905
gene_biotype: protein_coding
description:
  Casein kinase I (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4XVU1
symbol: NBR_LOCUS6945
gene_biotype: protein_coding
description:
  Anaphase-promoting complex subunit 2 (inferred by orthology to a C. elegans protein); Belongs to the cullin family.


ensembl_gene_id: A0A0N4XVX1
symbol: NBR_LOCUS6984
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]


ensembl_gene_id: A0A0N4XW04
symbol: NBR_LOCUS7021
gene_biotype: protein_coding
description:
  Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.


ensembl_gene_id: A0A0N4XW73
symbol: NBR_LOCUS7121
gene_biotype: protein_coding
description:
  5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. Plays a role in maintenance of steady-state concentration and turnover of microRNAs (miRNA) by degradation of mature miRNA. Degradation role is enhanced when in complex with paxt-1. Partially redundant to xrn-1 in miRNA guide strand degradation. Implicated in differential regulation of mRNAs such as let-7 by controlling the accumulation of mature miRNA. Positively regulates molting of the pharyngeal cuticle.


ensembl_gene_id: A0A0N4XW78
symbol: NBR_LOCUS7127
gene_biotype: protein_coding
description:
  Guanine nucleotide-binding protein alpha-12 subunit (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4XWC4
symbol: NBR_LOCUS7181
gene_biotype: protein_coding
description:
  Tyramine receptor tyra-2 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4XWC7
symbol: NBR_LOCUS7186
gene_biotype: protein_coding
description:
  Probable G-protein coupled receptor (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4XWG4
symbol: NBR_LOCUS7231
gene_biotype: protein_coding
description:
  Protein lethal(2)essential for life (inferred by orthology to a D. melanogaster protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: A0A0N4XWH9
symbol: NBR_LOCUS7250
gene_biotype: protein_coding
description:
  Putative syntaxin-2 (inferred by orthology to a C. elegans protein); Belongs to the syntaxin family.


ensembl_gene_id: A0A0N4XWK9
symbol: NBR_LOCUS7291
gene_biotype: protein_coding
description:
  Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.


ensembl_gene_id: A0A0N4XWQ5
symbol: NBR_LOCUS7348
gene_biotype: protein_coding
description:
  GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.


ensembl_gene_id: A0A0N4XWV1
symbol: NBR_LOCUS7405
gene_biotype: protein_coding
description:
  Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.


ensembl_gene_id: A0A0N4XX16
symbol: NBR_LOCUS7486
gene_biotype: protein_coding
description:
  Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: A0A0N4XX62
symbol: NBR_LOCUS7546
gene_biotype: protein_coding
description:
  FLR-1 (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A0N4XXL6
symbol: LSM4
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A0N4XXL9
symbol: NBR_LOCUS7750
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: A0A0N4XXN4
symbol: NBR_LOCUS7769
gene_biotype: protein_coding
description:
  40S ribosomal protein S15 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS19 family.


ensembl_gene_id: A0A0N4XXQ8
symbol: NBR_LOCUS7798
gene_biotype: protein_coding
description:
  Probable 3',5'-cyclic phosphodiesterase pde-4 (inferred by orthology to a C. elegans protein); Belongs to the cyclic nucleotide phosphodiesterase family.


ensembl_gene_id: A0A0N4XXS0
symbol: NBR_LOCUS7811
gene_biotype: protein_coding
description:
  Putative methyltransferase NSUN5 (inferred by orthology to a human protein); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A0N4XXW4
symbol: NBR_LOCUS7873
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 G2 (inferred by orthology to a human protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A0N4XXX7
symbol: NBR_LOCUS7892
gene_biotype: protein_coding
description:
  Methylthioribose-1-phosphate isomerase (inferred by orthology to a C. elegans protein); Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: A0A0N4XY38
symbol: NBR_LOCUS7969
gene_biotype: protein_coding
description:
  F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.


ensembl_gene_id: A0A0N4XY61
symbol: NBR_LOCUS7995
gene_biotype: protein_coding
description:
  Probable 3',5'-cyclic phosphodiesterase pde-6 (inferred by orthology to a C. elegans protein); Belongs to the cyclic nucleotide phosphodiesterase family.


ensembl_gene_id: A0A0N4XY63
symbol: NBR_LOCUS7999
gene_biotype: protein_coding
description:
  Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A0N4XY68
symbol: NBR_LOCUS8005
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: A0A0N4XY78
symbol: NBR_LOCUS8016
gene_biotype: protein_coding
description:
  TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4XYB7
symbol: NBR_LOCUS8066
gene_biotype: protein_coding
description:
  DIS3-like exonuclease 2 (inferred by orthology to a C. elegans protein); Belongs to the RNR ribonuclease family.


ensembl_gene_id: A0A0N4XYC3
symbol: NBR_LOCUS8072
gene_biotype: protein_coding
description:
  2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).


ensembl_gene_id: A0A0N4XYM0
symbol: NBR_LOCUS8192
gene_biotype: protein_coding
description:
  Nucleoside-diphosphatase uda-1 (inferred by orthology to a C. elegans protein); Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: A0A0N4XYR6
symbol: NBR_LOCUS8248
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.


ensembl_gene_id: A0A0N4XYR8
symbol: NBR_LOCUS8250
gene_biotype: protein_coding
description:
  ADP-ribosylation factor-like protein 6 (inferred by orthology to a C. elegans protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4XYS8
symbol: NBR_LOCUS8261
gene_biotype: protein_coding
description:
  Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: A0A0N4XYT1
symbol: NBR_LOCUS8264
gene_biotype: protein_coding
description:
  Ribonuclease X25 (inferred by orthology to a D. melanogaster protein); Belongs to the RNase T2 family.


ensembl_gene_id: A0A0N4XYV1
symbol: NBR_LOCUS8295
gene_biotype: protein_coding
description:
  Putative adp,ATP carrier protein (inferred by orthology to a S. mansoni protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4XYX8
symbol: NBR_LOCUS8329
gene_biotype: protein_coding
description:
  Dehydrogenase/reductase SDR family member 1 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4XYZ0
symbol: NBR_LOCUS8347
gene_biotype: protein_coding
description:
  ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.


ensembl_gene_id: A0A0N4XYZ2
symbol: NBR_LOCUS8349
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase 7 (inferred by orthology to a human protein); Belongs to the peptidase C19 family.


ensembl_gene_id: A0A0N4XZ07
symbol: NBR_LOCUS8365
gene_biotype: protein_coding
description:
  Probable 26S protease regulatory subunit 4 (inferred by orthology to a C. elegans protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4XZ08
symbol: NBR_LOCUS8366
gene_biotype: protein_coding
description:
  Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase; Belongs to the ROX family.


ensembl_gene_id: A0A0N4XZ21
symbol: NBR_LOCUS8385
gene_biotype: protein_coding
description:
  Probable ATP-dependent RNA helicase DDX41 (inferred by orthology to a human protein); Belongs to the DEAD box helicase family.


ensembl_gene_id: A0A0N4XZ63
symbol: NBR_LOCUS8436
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: A0A0N4XZ75
symbol: NBR_LOCUS8452
gene_biotype: protein_coding
description:
  MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A0N4XZB3
symbol: NBR_LOCUS8503
gene_biotype: protein_coding
description:
  Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.


ensembl_gene_id: A0A0N4XZC1
symbol: NBR_LOCUS8512
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A0N4XZC9
symbol: NBR_LOCUS8524
gene_biotype: protein_coding
description:
  Glutamate-gated chloride channel subunit beta (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4XZD3
symbol: NBR_LOCUS8530
gene_biotype: protein_coding
description:
  ADP-ribosylation factor 6 (inferred by orthology to a human protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4XZK8
symbol: NBR_LOCUS8625
gene_biotype: protein_coding
description:
  Glucose transporter type 1 (inferred by orthology to a D. melanogaster protein); Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: A0A0N4XZL7
symbol: NBR_LOCUS8635
gene_biotype: protein_coding
description:
  Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A0N4XZN7
symbol: NBR_LOCUS8658
gene_biotype: protein_coding
description:
  Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.


ensembl_gene_id: A0A0N4XZP0
symbol: NBR_LOCUS8661
gene_biotype: protein_coding
description:
  Phosphoglucomutase (inferred by orthology to a D. melanogaster protein); Belongs to the phosphohexose mutase family.


ensembl_gene_id: A0A0N4XZQ7
symbol: NBR_LOCUS8686
gene_biotype: protein_coding
description:
  Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).


ensembl_gene_id: A0A0N4XZR2
symbol: NBR_LOCUS8693
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase ATM (inferred by orthology to a C. elegans protein); Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A0N4XZT1
symbol: NBR_LOCUS8716
gene_biotype: protein_coding
description:
  RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.


ensembl_gene_id: A0A0N4XZU9
symbol: NBR_LOCUS8745
gene_biotype: protein_coding
description:
  5-hydroxytryptamine receptor 7 (inferred by orthology to a human protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4XZW1
symbol: NBR_LOCUS8763
gene_biotype: protein_coding
description:
  Guanine nucleotide-binding protein alpha-10 subunit (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4XZX8
symbol: NBR_LOCUS8787
gene_biotype: protein_coding
description:
  Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: A0A0N4Y001
symbol: NBR_LOCUS8814
gene_biotype: protein_coding
description:
  Mitochondrial import receptor subunit TOM20 homolog (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4Y061
symbol: NBR_LOCUS8881
gene_biotype: protein_coding
description:
  Mitochondrial 2-oxodicarboxylate carrier (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4Y079
symbol: NBR_LOCUS8906
gene_biotype: protein_coding
description:
  Cathepsin B-like cysteine proteinase 6 (inferred by orthology to a C. elegans protein); Belongs to the peptidase C1 family.


ensembl_gene_id: A0A0N4Y098
symbol: NBR_LOCUS8933
gene_biotype: protein_coding
description:
  Proton-gated ion channel subunit pbo-5 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4Y0F3
symbol: NBR_LOCUS9001
gene_biotype: protein_coding
description:
  Glycogen synthase kinase-3 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4Y0G0
symbol: NBR_LOCUS9010
gene_biotype: protein_coding
description:
  Solute carrier family 25 member 44 (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4Y0G1
symbol: NBR_LOCUS9011
gene_biotype: protein_coding
description:
  26S protease regulatory subunit 6A (inferred by orthology to a human protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4Y0H1
symbol: NBR_LOCUS9022
gene_biotype: protein_coding
description:
  Probable methylthioribulose-1-phosphate dehydratase (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4Y0I5
symbol: NBR_LOCUS9041
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A0N4Y0J0
symbol: NBR_LOCUS9048
gene_biotype: protein_coding
description:
  Endoribonuclease dcr-1 (inferred by orthology to a C. elegans protein); Belongs to the helicase family. Dicer subfamily.


ensembl_gene_id: A0A0N4Y0J2
symbol: NBR_LOCUS9050
gene_biotype: protein_coding
description:
  Unconventional myosin-Id (inferred by orthology to a human protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A0N4Y0L4
symbol: NBR_LOCUS9082
gene_biotype: protein_coding
description:
  Methionine--tRNA ligase, cytoplasmic (inferred by orthology to a C. elegans protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4Y0L6
symbol: NBR_LOCUS9086
gene_biotype: protein_coding
description:
  40S ribosomal protein S11 (inferred by orthology to a human protein); Belongs to the universal ribosomal protein uS17 family.


ensembl_gene_id: A0A0N4Y0M4
symbol: NBR_LOCUS9095
gene_biotype: protein_coding
description:
  Cholecystokinin receptor 2 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4Y0P8
symbol: NBR_LOCUS9130
gene_biotype: protein_coding
description:
  Serine/threonine kinase (inferred by orthology to a S. mansoni protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4Y0Q3
symbol: NBR_LOCUS9136
gene_biotype: protein_coding
description:
  Lysophospholipid acyltransferase 7 (inferred by orthology to a C. elegans protein); Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A0N4Y1A6
symbol: NBR_LOCUS9387
gene_biotype: protein_coding
description:
  Putative serine/threonine-protein kinase (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4Y1C2
symbol: NBR_LOCUS9408
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.


ensembl_gene_id: A0A0N4Y1C7
symbol: LSM3
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A0N4Y1F1
symbol: NBR_LOCUS9445
gene_biotype: protein_coding
description:
  Protein ROP (inferred by orthology to a D. melanogaster protein); Belongs to the STXBP/unc-18/SEC1 family.


ensembl_gene_id: A0A0N4Y1I0
symbol: NBR_LOCUS9480
gene_biotype: protein_coding
description:
  40S ribosomal protein S3 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: A0A0N4Y1I8
symbol: NBR_LOCUS9491
gene_biotype: protein_coding
description:
  Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family.


ensembl_gene_id: A0A0N4Y1S8
symbol: NBR_LOCUS9599
gene_biotype: protein_coding
description:
  Glycosylphosphatidylinositol anchor attachment 1 protein (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4Y1U8
symbol: NBR_LOCUS9623
gene_biotype: protein_coding
description:
  Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.


ensembl_gene_id: A0A0N4Y1Z0
symbol: NBR_LOCUS9671
gene_biotype: protein_coding
description:
  GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.


ensembl_gene_id: A0A0N4Y214
symbol: NBR_LOCUS9706
gene_biotype: protein_coding
description:
  Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: A0A0N4Y262
symbol: NBR_LOCUS9770
gene_biotype: protein_coding
description:
  DNA ligase 3 (inferred by orthology to a human protein); Belongs to the ATP-dependent DNA ligase family.


ensembl_gene_id: A0A0N4Y287
symbol: NBR_LOCUS9804
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.


ensembl_gene_id: A0A0N4Y298
symbol: NBR_LOCUS9820
gene_biotype: protein_coding
description:
  Sodium-dependent multivitamin transporter (inferred by orthology to a human protein); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: A0A0N4Y2A2
symbol: NBR_LOCUS9827
gene_biotype: protein_coding
description:
  Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A0N4Y2D2
symbol: NBR_LOCUS9863
gene_biotype: protein_coding
description:
  Ethanolaminephosphotransferase 1 (inferred by orthology to a human protein); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: A0A0N4Y2F6
symbol: NBR_LOCUS9896
gene_biotype: protein_coding
description:
  N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.


ensembl_gene_id: A0A0N4Y2L4
symbol: NBR_LOCUS9971
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.


ensembl_gene_id: A0A0N4Y2L5
symbol: NBR_LOCUS9972
gene_biotype: protein_coding
description:
  Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).


ensembl_gene_id: A0A0N4Y2L6
symbol: NBR_LOCUS9973
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the dus family.


ensembl_gene_id: A0A0N4Y2L9
symbol: NBR_LOCUS9977
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.


ensembl_gene_id: A0A0N4Y2M2
symbol: NBR_LOCUS9980
gene_biotype: protein_coding
description:
  Cyclin-dependent kinase CDK-4 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4Y364
symbol: NBR_LOCUS10222
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase family 8 member A1 (inferred by orthology to a human protein); Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: A0A0N4Y382
symbol: NBR_LOCUS10245
gene_biotype: protein_coding
description:
  Carnitine O-palmitoyltransferase 2, mitochondrial (inferred by orthology to a human protein); Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: A0A0N4Y389
symbol: NBR_LOCUS10254
gene_biotype: protein_coding
description:
  40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.


ensembl_gene_id: A0A0N4Y3A5
symbol: NBR_LOCUS10272
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit beta (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4Y3C5
symbol: NBR_LOCUS10297
gene_biotype: protein_coding
description:
  Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.


ensembl_gene_id: A0A0N4Y3E1
symbol: NBR_LOCUS10315
gene_biotype: protein_coding
description:
  U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.


ensembl_gene_id: A0A0N4Y3E5
symbol: NBR_LOCUS10320
gene_biotype: protein_coding
description:
  Probable L-xylulose reductase (inferred by orthology to a C. elegans protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4Y3H1
symbol: NBR_LOCUS10357
gene_biotype: protein_coding
description:
  Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.


ensembl_gene_id: A0A0N4Y3I1
symbol: NBR_LOCUS10373
gene_biotype: protein_coding
description:
  Mitochondrial 2-oxoglutarate/malate carrier protein (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4Y3J1
symbol: NBR_LOCUS10386
gene_biotype: protein_coding
description:
  Putative nachr subunit (inferred by orthology to a S. mansoni protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4Y3J6
symbol: NBR_LOCUS10391
gene_biotype: protein_coding
description:
  Probable arginine kinase (inferred by orthology to a C. elegans protein); Belongs to the ATP:guanido phosphotransferase family.


ensembl_gene_id: A0A0N4Y3L0
symbol: NBR_LOCUS10408
gene_biotype: protein_coding
description:
  Probable calcium-binding mitochondrial carrier (inferred by orthology to a C. elegans protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4Y3N1
symbol: NBR_LOCUS10431
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


ensembl_gene_id: A0A0N4Y3N5
symbol: NBR_LOCUS10436
gene_biotype: protein_coding
description:
  Nucleoporin SEH1 (inferred by orthology to a C. elegans protein); Belongs to the WD repeat SEC13 family.


ensembl_gene_id: A0A0N4Y3T6
symbol: NBR_LOCUS10502
gene_biotype: protein_coding
description:
  Degenerin unc-8 (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A0N4Y3T9
symbol: NBR_LOCUS10505
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).


ensembl_gene_id: A0A0N4Y3X5
symbol: NBR_LOCUS10550
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: A0A0N4Y3X7
symbol: NBR_LOCUS10552
gene_biotype: protein_coding
description:
  Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.


ensembl_gene_id: A0A0N4Y3Z6
symbol: NBR_LOCUS10576
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphatase-related (inferred by orthology to a S. mansoni protein); Belongs to the FBPase class 1 family.


ensembl_gene_id: A0A0N4Y421
symbol: NBR_LOCUS10611
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm6 (inferred by orthology to a human protein); Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.


ensembl_gene_id: A0A0N4Y440
symbol: NBR_LOCUS10633
gene_biotype: protein_coding
description:
  Protein-lysine N-methyltransferase NBR_LOCUS10633; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that methylates elongation factor 1-alpha. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.


ensembl_gene_id: A0A0N4Y442
symbol: NBR_LOCUS10635
gene_biotype: protein_coding
description:
  60S ribosomal protein L23 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: A0A0N4Y448
symbol: NBR_LOCUS10643
gene_biotype: protein_coding
description:
  Probable cytochrome P450 CYP44 (inferred by orthology to a C. elegans protein); Belongs to the cytochrome P450 family.


ensembl_gene_id: A0A0N4Y482
symbol: NBR_LOCUS10684
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs.


ensembl_gene_id: A0A0N4Y485
symbol: NBR_LOCUS10687
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.


ensembl_gene_id: A0A0N4Y489
symbol: NBR_LOCUS10693
gene_biotype: protein_coding
description:
  Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.


ensembl_gene_id: A0A0N4Y494
symbol: NBR_LOCUS10698
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 1 (inferred by orthology to a C. elegans protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A0N4Y4C4
symbol: NBR_LOCUS10739
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.


ensembl_gene_id: A0A0N4Y4E7
symbol: NBR_LOCUS10767
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: A0A0N4Y4H3
symbol: NBR_LOCUS10794
gene_biotype: protein_coding
description:
  Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The  [...]


ensembl_gene_id: A0A0N4Y4L7
symbol: NBR_LOCUS10851
gene_biotype: protein_coding
description:
  4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.


ensembl_gene_id: A0A0N4Y4P7
symbol: NBR_LOCUS10894
gene_biotype: protein_coding
description:
  NTR-1 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4Y4U0
symbol: LSM5
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.


ensembl_gene_id: A0A0N4Y4U9
symbol: NBR_LOCUS10956
gene_biotype: protein_coding
description:
  Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: A0A0N4Y4V0
symbol: NBR_LOCUS10957
gene_biotype: protein_coding
description:
  Glutathione S-transferase P (inferred by orthology to a human protein); Belongs to the GST superfamily.


ensembl_gene_id: A0A0N4Y4W1
symbol: NBR_LOCUS10970
gene_biotype: protein_coding
description:
  Alkylglycerol monooxygenase (inferred by orthology to a human protein); Belongs to the sterol desaturase family.


ensembl_gene_id: A0A0N4Y4X0
symbol: NBR_LOCUS10984
gene_biotype: protein_coding
description:
  Alkylglycerol monooxygenase homolog (inferred by orthology to a C. elegans protein); Belongs to the sterol desaturase family.


ensembl_gene_id: A0A0N4Y4X9
symbol: NBR_LOCUS10994
gene_biotype: protein_coding
description:
  Actin-related protein 3 (inferred by orthology to a C. elegans protein); Belongs to the actin family.


ensembl_gene_id: A0A0N4Y4Y5
symbol: NBR_LOCUS11001
gene_biotype: protein_coding
description:
  Frizzled-2 (inferred by orthology to a D. melanogaster protein); Belongs to the G-protein coupled receptor Fz/Smo family.


ensembl_gene_id: A0A0N4Y533
symbol: NBR_LOCUS11069
gene_biotype: protein_coding
description:
  T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.


ensembl_gene_id: A0A0N4Y547
symbol: NBR_LOCUS11085
gene_biotype: protein_coding
description:
  Putative neuropeptide Y receptor 11 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4Y570
symbol: NBR_LOCUS11112
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A0N4Y588
symbol: MED20
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4Y5A6
symbol: NBR_LOCUS11155
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A0N4Y5G9
symbol: NBR_LOCUS11244
gene_biotype: protein_coding
description:
  Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.


ensembl_gene_id: A0A0N4Y5J1
symbol: NBR_LOCUS11269
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


ensembl_gene_id: A0A0N4Y5K1
symbol: NBR_LOCUS11283
gene_biotype: protein_coding
description:
  Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. In the CBC complex, ncbp-2 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp-1 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.


ensembl_gene_id: A0A0N4Y5M0
symbol: NBR_LOCUS11308
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A0N4Y5Z9
symbol: NBR_LOCUS11475
gene_biotype: protein_coding
description:
  Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: A0A0N4Y625
symbol: NBR_LOCUS11505
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A0N4Y638
symbol: NBR_LOCUS11514
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (inferred by orthology to a human protein); Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.


ensembl_gene_id: A0A0N4Y664
symbol: NBR_LOCUS11554
gene_biotype: protein_coding
description:
  Probable G-protein coupled receptor tkr-1 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4Y689
symbol: NBR_LOCUS11588
gene_biotype: protein_coding
description:
  Guanine nucleotide-binding protein alpha-17 subunit (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4Y699
symbol: NBR_LOCUS11599
gene_biotype: protein_coding
description:
  ADP-ribosylation factor-like protein 1 (inferred by orthology to a C. elegans protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4Y6G8
symbol: NBR_LOCUS11678
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]


ensembl_gene_id: A0A0N4Y6H3
symbol: NBR_LOCUS11684
gene_biotype: protein_coding
description:
  O-acyltransferase (inferred by orthology to a C. elegans protein); Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A0N4Y6H7
symbol: NBR_LOCUS11688
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A0N4Y6H8
symbol: NBR_LOCUS11689
gene_biotype: protein_coding
description:
  DNA mismatch repair protein Msh2 (inferred by orthology to a human protein); Component of the post-replicative DNA mismatch repair system (MMR).


ensembl_gene_id: A0A0N4Y6K2
symbol: NBR_LOCUS11719
gene_biotype: protein_coding
description:
  Tat-binding homolog 7 (inferred by orthology to a C. elegans protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4Y6N7
symbol: NBR_LOCUS11760
gene_biotype: protein_coding
description:
  Thyrotropin-releasing hormone receptor (inferred by orthology to a human protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4Y6P7
symbol: NBR_LOCUS11773
gene_biotype: protein_coding
description:
  Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.


ensembl_gene_id: A0A0N4Y6T2
symbol: NBR_LOCUS11818
gene_biotype: protein_coding
description:
  Putative dihydrofolate reductase (inferred by orthology to a C. elegans protein); Belongs to the dihydrofolate reductase family.


ensembl_gene_id: A0A0N4Y6W0
symbol: NBR_LOCUS11852
gene_biotype: protein_coding
description:
  Calx-beta domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A0N4Y6W7
symbol: NBR_LOCUS11862
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery.


ensembl_gene_id: A0A0N4Y6X9
symbol: NBR_LOCUS11878
gene_biotype: protein_coding
description:
  3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.


ensembl_gene_id: A0A0N4Y6Y8
symbol: NBR_LOCUS11889
gene_biotype: protein_coding
description:
  Probable small nuclear ribonucleoprotein F (inferred by orthology to a C. elegans protein); Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.


ensembl_gene_id: A0A0N4Y709
symbol: NBR_LOCUS11915
gene_biotype: protein_coding
description:
  Transcription-associated protein 1 (inferred by orthology to a D. melanogaster protein); Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A0N4Y777
symbol: NBR_LOCUS11996
gene_biotype: protein_coding
description:
  DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.


ensembl_gene_id: A0A0N4Y778
symbol: NBR_LOCUS11997
gene_biotype: protein_coding
description:
  Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: A0A0N4Y799
symbol: NBR_LOCUS12023
gene_biotype: protein_coding
description:
  Putative transmembrane 4 superfamily member (inferred by orthology to a S. mansoni protein); Belongs to the tetraspanin (TM4SF) family.


ensembl_gene_id: A0A0N4Y7D6
symbol: NBR_LOCUS12066
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein VTA1 homolog (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4Y7E5
symbol: NBR_LOCUS12078
gene_biotype: protein_coding
description:
  Suppressor of presenilin-2 (inferred by orthology to a C. elegans protein); Belongs to the nucleosome assembly protein (NAP) family.


ensembl_gene_id: A0A0N4Y7F7
symbol: NBR_LOCUS12091
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.


ensembl_gene_id: A0A0N4Y7G1
symbol: NBR_LOCUS12095
gene_biotype: protein_coding
description:
  Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family.


ensembl_gene_id: A0A0N4Y7H6
symbol: NBR_LOCUS12112
gene_biotype: protein_coding
description:
  N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4Y7I5
symbol: NBR_LOCUS12122
gene_biotype: protein_coding
description:
  Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A0N4Y7J3
symbol: NBR_LOCUS12131
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase, mitochondrial (inferred by orthology to a human protein); Belongs to the IPP transferase family.


ensembl_gene_id: A0A0N4Y7N1
symbol: NBR_LOCUS12174
gene_biotype: protein_coding
description:
  Intermediate filament protein ifa-1 (inferred by orthology to a C. elegans protein); Belongs to the intermediate filament family.


ensembl_gene_id: A0A0N4Y7P9
symbol: NBR_LOCUS12196
gene_biotype: protein_coding
description:
  39S ribosomal protein L22, mitochondrial (inferred by orthology to a human protein); Belongs to the universal ribosomal protein uL22 family.


ensembl_gene_id: A0A0N4Y7U9
symbol: NBR_LOCUS12258
gene_biotype: protein_coding
description:
  Actin-depolymerizing factor 1 (inferred by orthology to a C. elegans protein); Belongs to the actin-binding proteins ADF family.


ensembl_gene_id: A0A0N4Y7V5
symbol: NBR_LOCUS12265
gene_biotype: protein_coding
description:
  Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4Y7W7
symbol: NBR_LOCUS12278
gene_biotype: protein_coding
description:
  Spermidine synthase (inferred by orthology to a human protein); Belongs to the spermidine/spermine synthase family.


ensembl_gene_id: A0A0N4Y7X3
symbol: NBR_LOCUS12285
gene_biotype: protein_coding
description:
  Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.


ensembl_gene_id: A0A0N4Y7Z0
symbol: NBR_LOCUS12303
gene_biotype: protein_coding
description:
  General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.


ensembl_gene_id: A0A0N4Y834
symbol: NBR_LOCUS12354
gene_biotype: protein_coding
description:
  Probable enoyl-CoA hydratase, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A0N4Y839
symbol: NBR_LOCUS12362
gene_biotype: protein_coding
description:
  Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.


ensembl_gene_id: A0A0N4Y852
symbol: NBR_LOCUS12378
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A0N4Y869
symbol: NBR_LOCUS12399
gene_biotype: protein_coding
description:
  Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.


ensembl_gene_id: A0A0N4Y898
symbol: NBR_LOCUS12436
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: A0A0N4Y8A4
symbol: NBR_LOCUS12444
gene_biotype: protein_coding
description:
  Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.


ensembl_gene_id: A0A0N4Y8A7
symbol: NBR_LOCUS12448
gene_biotype: protein_coding
description:
  Neuropeptide Y receptor (inferred by orthology to a D. melanogaster protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4Y8A8
symbol: NBR_LOCUS12449
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A0N4Y8A9
symbol: NBR_LOCUS12450
gene_biotype: protein_coding
description:
  Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: A0A0N4Y8D7
symbol: NBR_LOCUS12482
gene_biotype: protein_coding
description:
  Proton-gated ion channel subunit pbo-6 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4Y8E1
symbol: NBR_LOCUS12486
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.


ensembl_gene_id: A0A0N4Y8F3
symbol: NBR_LOCUS12501
gene_biotype: protein_coding
description:
  ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...]


ensembl_gene_id: A0A0N4Y8I1
symbol: NBR_LOCUS12532
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase DDX42 (inferred by orthology to a human protein); Belongs to the DEAD box helicase family.


ensembl_gene_id: A0A0N4Y8J3
symbol: NBR_LOCUS12548
gene_biotype: protein_coding
description:
  Globin-like protein 6 (inferred by orthology to a C. elegans protein); Belongs to the globin family.


ensembl_gene_id: A0A0N4Y8T6
symbol: NBR_LOCUS12664
gene_biotype: protein_coding
description:
  Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.


ensembl_gene_id: A0A0N4Y8Z9
symbol: NBR_LOCUS12746
gene_biotype: protein_coding
description:
  GrpE protein homolog, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the GrpE family.


ensembl_gene_id: A0A0N4Y927
symbol: NBR_LOCUS12781
gene_biotype: protein_coding
description:
  Myosin-3 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A0N4Y987
symbol: NBR_LOCUS12851
gene_biotype: protein_coding
description:
  Translationally-controlled tumor protein homolog (inferred by orthology to a C. elegans protein); Belongs to the TCTP family.


ensembl_gene_id: A0A0N4Y989
symbol: NBR_LOCUS12853
gene_biotype: protein_coding
description:
  Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.


ensembl_gene_id: A0A0N4Y9W7
symbol: NBR_LOCUS13141
gene_biotype: protein_coding
description:
  Exostosin-2 (inferred by orthology to a C. elegans protein); Belongs to the glycosyltransferase 47 family.


ensembl_gene_id: A0A0N4Y9X2
symbol: NBR_LOCUS13147
gene_biotype: protein_coding
description:
  RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.


ensembl_gene_id: A0A0N4Y9Y7
symbol: FEN1
gene_biotype: protein_coding
description:
  Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as  [...]


ensembl_gene_id: A0A0N4Y9Z9
symbol: NBR_LOCUS13180
gene_biotype: protein_coding
description:
  60S ribosomal protein L27a (inferred by orthology to a human protein); Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: A0A0N4YA02
symbol: NBR_LOCUS13183
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.


ensembl_gene_id: A0A0N4YA54
symbol: EIF6
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.


ensembl_gene_id: A0A0N4YA91
symbol: NBR_LOCUS13290
gene_biotype: protein_coding
description:
  Intermediate filament protein ifb-1 (inferred by orthology to a C. elegans protein); Belongs to the intermediate filament family.


ensembl_gene_id: A0A0N4YAF1
symbol: NBR_LOCUS13364
gene_biotype: protein_coding
description:
  Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.


ensembl_gene_id: A0A0N4YAL6
symbol: NBR_LOCUS13442
gene_biotype: protein_coding
description:
  S-adenosylmethionine mitochondrial carrier protein (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4YAM0
symbol: NBR_LOCUS13447
gene_biotype: protein_coding
description:
  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: A0A0N4YAQ1
symbol: NBR_LOCUS13488
gene_biotype: protein_coding
description:
  Uncharacterized serine carboxypeptidase F13S12.6 (inferred by orthology to a C. elegans protein); Belongs to the peptidase S10 family.


ensembl_gene_id: A0A0N4YAQ2
symbol: NBR_LOCUS13489
gene_biotype: protein_coding
description:
  Set1/Ash2 histone methyltransferase complex subunit ASH2 (inferred by orthology to a human protein).


ensembl_gene_id: A0A0N4YAR6
symbol: NBR_LOCUS13505
gene_biotype: protein_coding
description:
  Carrier protein (inferred by orthology to a C. elegans protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4YAS4
symbol: NBR_LOCUS13514
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase pelle (inferred by orthology to a D. melanogaster protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YAS9
symbol: NBR_LOCUS13522
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4YAT0
symbol: NBR_LOCUS13523
gene_biotype: protein_coding
description:
  Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.


ensembl_gene_id: A0A0N4YAU9
symbol: NBR_LOCUS13544
gene_biotype: protein_coding
description:
  Muscarinic acetylcholine receptor gar-3 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4YB01
symbol: NBR_LOCUS13606
gene_biotype: protein_coding
description:
  60S acidic ribosomal protein P2 (inferred by orthology to a human protein); Belongs to the eukaryotic ribosomal protein P1/P2 family.


ensembl_gene_id: A0A0N4YB05
symbol: NBR_LOCUS13611
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A0N4YB17
symbol: NBR_LOCUS11019
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family.


ensembl_gene_id: A0A0N4YB31
symbol: NBR_LOCUS13645
gene_biotype: protein_coding
description:
  Bifunctional glutamate/proline--tRNA ligase (inferred by orthology to a D. melanogaster protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4YB36
symbol: NBR_LOCUS13650
gene_biotype: protein_coding
description:
  26S protease regulatory subunit 8 (inferred by orthology to a human protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4YB55
symbol: NBR_LOCUS13672
gene_biotype: protein_coding
description:
  Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.


ensembl_gene_id: A0A0N4YB66
symbol: NBR_LOCUS13685
gene_biotype: protein_coding
description:
  MAGUK p55 subfamily member 5 (inferred by orthology to a human protein); Belongs to the MAGUK family.


ensembl_gene_id: A0A0N4YB67
symbol: NBR_LOCUS13686
gene_biotype: protein_coding
description:
  Aurora/IPL1-related protein kinase 2 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YB81
symbol: NBR_LOCUS13702
gene_biotype: protein_coding
description:
  Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.


ensembl_gene_id: A0A0N4YBA2
symbol: NBR_LOCUS13725
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: A0A0N4YBC0
symbol: NBR_LOCUS13747
gene_biotype: protein_coding
description:
  Nudix hydrolase 3 (inferred by orthology to a C. elegans protein); Belongs to the Nudix hydrolase family.


ensembl_gene_id: A0A0N4YBC8
symbol: NBR_LOCUS13756
gene_biotype: protein_coding
description:
  Protein SEC13 homolog (inferred by orthology to a C. elegans protein); Belongs to the WD repeat SEC13 family.


ensembl_gene_id: A0A0N4YBD5
symbol: NBR_LOCUS13765
gene_biotype: protein_coding
description:
  Aurora/Ipl1-related protein kinase 1 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YBG2
symbol: NBR_LOCUS13798
gene_biotype: protein_coding
description:
  Mpv17-like protein 2 (inferred by orthology to a human protein); Belongs to the peroxisomal membrane protein PXMP2/4 family.


ensembl_gene_id: A0A0N4YBH2
symbol: NBR_LOCUS13810
gene_biotype: protein_coding
description:
  Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.


ensembl_gene_id: A0A0N4YBI8
symbol: NBR_LOCUS13833
gene_biotype: protein_coding
description:
  Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.


ensembl_gene_id: A0A0N4YBK8
symbol: NBR_LOCUS13857
gene_biotype: protein_coding
description:
  Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).


ensembl_gene_id: A0A0N4YBQ1
symbol: NBR_LOCUS13911
gene_biotype: protein_coding
description:
  Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.


ensembl_gene_id: A0A0N4YBR8
symbol: NBR_LOCUS13936
gene_biotype: protein_coding
description:
  Peroxisomal multifunctional enzyme type 2 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4YBW7
symbol: NBR_LOCUS13997
gene_biotype: protein_coding
description:
  Transmembrane GTPase fzo-1 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A0N4YC12
symbol: NBR_LOCUS14055
gene_biotype: protein_coding
description:
  Alpha-tubulin N-acetyltransferase; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynam [...]


ensembl_gene_id: A0A0N4YC39
symbol: NBR_LOCUS14088
gene_biotype: protein_coding
description:
  Frizzled-4 (inferred by orthology to a D. melanogaster protein); Belongs to the G-protein coupled receptor Fz/Smo family.


ensembl_gene_id: A0A0N4YC72
symbol: NBR_LOCUS14127
gene_biotype: protein_coding
description:
  Probable cytochrome c 2.2 (inferred by orthology to a C. elegans protein); Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.


ensembl_gene_id: A0A0N4YC82
symbol: NBR_LOCUS14141
gene_biotype: protein_coding
description:
  Alanine--tRNA ligase, cytoplasmic (inferred by orthology to a C. elegans protein); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.


ensembl_gene_id: A0A0N4YCA7
symbol: NBR_LOCUS14167
gene_biotype: protein_coding
description:
  Integrin alpha ina-1 (inferred by orthology to a C. elegans protein); Belongs to the integrin alpha chain family.


ensembl_gene_id: A0A0N4YCF5
symbol: NBR_LOCUS14223
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.


ensembl_gene_id: A0A0N4YCF9
symbol: NBR_LOCUS14228
gene_biotype: protein_coding
description:
  Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.


ensembl_gene_id: A0A0N4YCG0
symbol: NBR_LOCUS14229
gene_biotype: protein_coding
description:
  40S ribosomal protein S23 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS12 family.


ensembl_gene_id: A0A0N4YCH2
symbol: NBR_LOCUS14241
gene_biotype: protein_coding
description:
  Translation initiation factor eIF-2B subunit beta (inferred by orthology to a human protein); Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: A0A0N4YCI4
symbol: NBR_LOCUS14253
gene_biotype: protein_coding
description:
  40S ribosomal protein S15a (inferred by orthology to a human protein); Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: A0A0N4YCJ0
symbol: NBR_LOCUS14259
gene_biotype: protein_coding
description:
  DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.


ensembl_gene_id: A0A0N4YCK3
symbol: NBR_LOCUS14274
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase nep-1 (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4YCR9
symbol: NBR_LOCUS14360
gene_biotype: protein_coding
description:
  Phosphatidylinositol 3-kinase age-1 (inferred by orthology to a C. elegans protein); Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: A0A0N4YCT0
symbol: NBR_LOCUS14376
gene_biotype: protein_coding
description:
  Tubulin_C domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


ensembl_gene_id: A0A0N4YD13
symbol: NBR_LOCUS14482
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.


ensembl_gene_id: A0A0N4YD28
symbol: NBR_LOCUS14499
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A0N4YD56
symbol: NBR_LOCUS14533
gene_biotype: protein_coding
description:
  Putative cytochrome b5 (inferred by orthology to a S. mansoni protein); Belongs to the cytochrome b5 family.


ensembl_gene_id: A0A0N4YD69
symbol: NBR_LOCUS14547
gene_biotype: protein_coding
description:
  Eukaryotic initiation factor 4A (inferred by orthology to a D. melanogaster protein); Belongs to the DEAD box helicase family.


ensembl_gene_id: A0A0N4YD85
symbol: NBR_LOCUS14563
gene_biotype: protein_coding
description:
  FMRFamide receptor (inferred by orthology to a D. melanogaster protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4YD92
symbol: NBR_LOCUS14573
gene_biotype: protein_coding
description:
  Piwi-like protein 1 (inferred by orthology to a zebrafish protein); Belongs to the argonaute family.


ensembl_gene_id: A0A0N4YDD7
symbol: NBR_LOCUS14630
gene_biotype: protein_coding
description:
  Probable muscarinic acetylcholine receptor gar-2 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4YDG6
symbol: NBR_LOCUS14664
gene_biotype: protein_coding
description:
  Guanine nucleotide-binding protein alpha-11 subunit (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4YDJ6
symbol: NBR_LOCUS14699
gene_biotype: protein_coding
description:
  Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-.


ensembl_gene_id: A0A0N4YDK8
symbol: NBR_LOCUS14712
gene_biotype: protein_coding
description:
  60S ribosomal protein L17 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uL22 family.


ensembl_gene_id: A0A0N4YDL3
symbol: NBR_LOCUS14717
gene_biotype: protein_coding
description:
  Putative ribosomal RNA methyltransferase NOP2 (inferred by orthology to a human protein); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: A0A0N4YDM0
symbol: NBR_LOCUS14725
gene_biotype: protein_coding
description:
  MAP kinase-activated protein kinase 2 (inferred by orthology to a D. melanogaster protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YDM3
symbol: NBR_LOCUS14728
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase Chk1 (inferred by orthology to a human protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YDN2
symbol: NBR_LOCUS14740
gene_biotype: protein_coding
description:
  Acetylcholine receptor subunit alpha-type acr-16 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4YDP7
symbol: NBR_LOCUS14761
gene_biotype: protein_coding
description:
  Tetraspanin-17 (inferred by orthology to a C. elegans protein); Belongs to the tetraspanin (TM4SF) family.


ensembl_gene_id: A0A0N4YDP9
symbol: MED6
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4YDT1
symbol: NBR_LOCUS14810
gene_biotype: protein_coding
description:
  GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.


ensembl_gene_id: A0A0N4YDW5
symbol: NBR_LOCUS14847
gene_biotype: protein_coding
description:
  Heat shock protein Hsp-12.2 (inferred by orthology to a C. elegans protein); Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: A0A0N4YDX1
symbol: NBR_LOCUS14854
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A0N4YE49
symbol: NBR_LOCUS14943
gene_biotype: protein_coding
description:
  26S protease regulatory subunit 4 (inferred by orthology to a human protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4YEF1
symbol: NBR_LOCUS15063
gene_biotype: protein_coding
description:
  Mitochondrial folate transporter/carrier (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4YEK9
symbol: NBR_LOCUS15142
gene_biotype: protein_coding
description:
  Oxoglutarate/malate carrier protein (inferred by orthology to a C. elegans protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A0N4YEP3
symbol: NBR_LOCUS15186
gene_biotype: protein_coding
description:
  Epidermal retinol dehydrogenase 2 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4YEP7
symbol: NBR_LOCUS15190
gene_biotype: protein_coding
description:
  Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.


ensembl_gene_id: A0A0N4YES1
symbol: NBR_LOCUS15219
gene_biotype: protein_coding
description:
  Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.


ensembl_gene_id: A0A0N4YET4
symbol: NBR_LOCUS15233
gene_biotype: protein_coding
description:
  Ca2+/calmodulin-dependent protein kinase kinase (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YF17
symbol: NBR_LOCUS15326
gene_biotype: protein_coding
description:
  DNA mismatch repair protein Msh6 (inferred by orthology to a human protein); Component of the post-replicative DNA mismatch repair system (MMR).


ensembl_gene_id: A0A0N4YF30
symbol: NBR_LOCUS15341
gene_biotype: protein_coding
description:
  Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.


ensembl_gene_id: A0A0N4YF44
symbol: NBR_LOCUS15359
gene_biotype: protein_coding
description:
  Calcium/calmodulin-dependent protein kinase type II (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4YF52
symbol: NBR_LOCUS15370
gene_biotype: protein_coding
description:
  Cytochrome P450 daf-9 (inferred by orthology to a C. elegans protein); Belongs to the cytochrome P450 family.


ensembl_gene_id: A0A0N4YF67
symbol: NBR_LOCUS15386
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase dkf-2 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YFG4
symbol: NBR_LOCUS15498
gene_biotype: protein_coding
description:
  Mitochondrial GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: A0A0N4YFQ7
symbol: NBR_LOCUS15602
gene_biotype: protein_coding
description:
  NEDD8-conjugating enzyme ubc-12 (inferred by orthology to a C. elegans protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A0N4YFU6
symbol: NBR_LOCUS15646
gene_biotype: protein_coding
description:
  Ethylmalonyl-CoA decarboxylase (inferred by orthology to a human protein); Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A0N4YFW5
symbol: NBR_LOCUS15671
gene_biotype: protein_coding
description:
  Cathepsin L (inferred by orthology to a D. melanogaster protein); Belongs to the peptidase C1 family.


ensembl_gene_id: A0A0N4YG05
symbol: NBR_LOCUS15717
gene_biotype: protein_coding
description:
  ADP-ribosylation factor 1-like 1 (inferred by orthology to a C. elegans protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4YG29
symbol: NBR_LOCUS15744
gene_biotype: protein_coding
description:
  Sterol 4-C-methyltransferase strm-1 (inferred by orthology to a C. elegans protein); Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.


ensembl_gene_id: A0A0N4YG77
symbol: PAN3
gene_biotype: protein_coding
description:
  PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]


ensembl_gene_id: A0A0N4YGA2
symbol: NBR_LOCUS15831
gene_biotype: protein_coding
description:
  40S ribosomal protein S2 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: A0A0N4YGB6
symbol: NBR_LOCUS15846
gene_biotype: protein_coding
description:
  Farnesyl pyrophosphate synthase (inferred by orthology to a human protein); Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: A0A0N4YGB7
symbol: NBR_LOCUS15847
gene_biotype: protein_coding
description:
  Histone H4 (inferred by orthology to a zebrafish protein); Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.


ensembl_gene_id: A0A0N4YGC3
symbol: NBR_LOCUS15856
gene_biotype: protein_coding
description:
  Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.


ensembl_gene_id: A0A0N4YGC7
symbol: NBR_LOCUS15860
gene_biotype: protein_coding
description:
  Aquaporin-8 (inferred by orthology to a human protein); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: A0A0N4YGE2
symbol: NBR_LOCUS15878
gene_biotype: protein_coding
description:
  Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.


ensembl_gene_id: A0A0N4YGG1
symbol: NBR_LOCUS15897
gene_biotype: protein_coding
description:
  Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family.


ensembl_gene_id: A0A0N4YGK2
symbol: MED15
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4YGS0
symbol: NBR_LOCUS16020
gene_biotype: protein_coding
description:
  Fructose-1,6-bisphosphatase (inferred by orthology to a C. elegans protein); Belongs to the FBPase class 1 family.


ensembl_gene_id: A0A0N4YGT1
symbol: NBR_LOCUS16031
gene_biotype: protein_coding
description:
  Putative bolA-like protein (inferred by orthology to a C. elegans protein); Belongs to the BolA/IbaG family.


ensembl_gene_id: A0A0N4YGX2
symbol: NBR_LOCUS16077
gene_biotype: protein_coding
description:
  V-type proton ATPase 21 kDa proteolipid subunit (inferred by orthology to a human protein); Belongs to the V-ATPase proteolipid subunit family.


ensembl_gene_id: A0A0N4YH21
symbol: NBR_LOCUS16135
gene_biotype: protein_coding
description:
  Putative syntaxin 6 (inferred by orthology to a C. elegans protein); Belongs to the syntaxin family.


ensembl_gene_id: A0A0N4YH89
symbol: NBR_LOCUS16209
gene_biotype: protein_coding
description:
  Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.


ensembl_gene_id: A0A0N4YHA3
symbol: NBR_LOCUS16225
gene_biotype: protein_coding
description:
  Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A0N4YHF0
symbol: NBR_LOCUS16288
gene_biotype: protein_coding
description:
  Malate dehydrogenase (inferred by orthology to a C. elegans protein); Belongs to the LDH/MDH superfamily.


ensembl_gene_id: A0A0N4YHI0
symbol: NBR_LOCUS16319
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase-like protein 1 (inferred by orthology to a C. elegans protein); Belongs to the alpha-carbonic anhydrase family.


ensembl_gene_id: A0A0N4YHM5
symbol: NBR_LOCUS16372
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase II (inferred by orthology to a S. mansoni protein); Belongs to the alpha-carbonic anhydrase family.


ensembl_gene_id: A0A0N4YHM6
symbol: NBR_LOCUS16373
gene_biotype: protein_coding
description:
  Neuromedin U receptor (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A0N4YHN1
symbol: NBR_LOCUS16378
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.


ensembl_gene_id: A0A0N4YHR1
symbol: NBR_LOCUS16414
gene_biotype: protein_coding
description:
  G2/mitotic-specific cyclin-B3 (inferred by orthology to a C. elegans protein); Belongs to the cyclin family.


ensembl_gene_id: A0A0N4YHX5
symbol: NBR_LOCUS16489
gene_biotype: protein_coding
description:
  G1/S-specific cyclin-E (inferred by orthology to a C. elegans protein); Belongs to the cyclin family.


ensembl_gene_id: A0A0N4YHX7
symbol: NBR_LOCUS16491
gene_biotype: protein_coding
description:
  Methyltransferase-like protein 20 homolog (inferred by orthology to a C. elegans protein); Belongs to the eukaryotic ribosomal protein P1/P2 family.


ensembl_gene_id: A0A0N4YI60
symbol: NBR_LOCUS16583
gene_biotype: protein_coding
description:
  Frizzled (inferred by orthology to a D. melanogaster protein); Belongs to the G-protein coupled receptor Fz/Smo family.


ensembl_gene_id: A0A0N4YI87
symbol: NBR_LOCUS16615
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.


ensembl_gene_id: A0A0N4YIH4
symbol: NBR_LOCUS16714
gene_biotype: protein_coding
description:
  Sodium/potassium/calcium exchanger Nckx30C (inferred by orthology to a D. melanogaster protein); Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: A0A0N4YIJ3
symbol: NBR_LOCUS16737
gene_biotype: protein_coding
description:
  Putative clathrin coat assembly protein ap-1 (inferred by orthology to a S. mansoni protein); Belongs to the adaptor complexes medium subunit family.


ensembl_gene_id: A0A0N4YIJ6
symbol: NBR_LOCUS16740
gene_biotype: protein_coding
description:
  Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.


ensembl_gene_id: A0A0N4YIK0
symbol: NBR_LOCUS16745
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 33B (inferred by orthology to a human protein); Belongs to the STXBP/unc-18/SEC1 family.


ensembl_gene_id: A0A0N4YIR6
symbol: NBR_LOCUS16819
gene_biotype: protein_coding
description:
  RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.


ensembl_gene_id: A0A0N4YIT4
symbol: NBR_LOCUS16841
gene_biotype: protein_coding
description:
  26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.


ensembl_gene_id: A0A0N4YJ30
symbol: NBR_LOCUS16953
gene_biotype: protein_coding
description:
  Probable ubiquitin carboxyl-terminal hydrolase 46 (inferred by orthology to a C. elegans protein); Belongs to the peptidase C19 family.


ensembl_gene_id: A0A0N4YJ58
symbol: NBR_LOCUS16986
gene_biotype: protein_coding
description:
  ADP-ribosylation factor related (inferred by orthology to a C. elegans protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A0N4YJ72
symbol: NBR_LOCUS17000
gene_biotype: protein_coding
description:
  Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.


ensembl_gene_id: A0A0N4YJD7
symbol: NBR_LOCUS17072
gene_biotype: protein_coding
description:
  Alanine--glyoxylate aminotransferase 2-like (inferred by orthology to a C. elegans protein); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A0N4YJF7
symbol: NBR_LOCUS17096
gene_biotype: protein_coding
description:
  Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.


ensembl_gene_id: A0A0N4YJI2
symbol: MED19
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4YJM3
symbol: NBR_LOCUS17177
gene_biotype: protein_coding
description:
  Retinol dehydrogenase 10 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4YJM9
symbol: NBR_LOCUS17184
gene_biotype: protein_coding
description:
  Probable ATP-dependent RNA helicase DDX55 homolog (inferred by orthology to a C. elegans protein); Belongs to the DEAD box helicase family.


ensembl_gene_id: A0A0N4YJP1
symbol: NBR_LOCUS17199
gene_biotype: protein_coding
description:
  Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.


ensembl_gene_id: A0A0N4YJQ1
symbol: NBR_LOCUS17209
gene_biotype: protein_coding
description:
  Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.


ensembl_gene_id: A0A0N4YJT1
symbol: NBR_LOCUS17246
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase-like protein 2 (inferred by orthology to a C. elegans protein); Belongs to the alpha-carbonic anhydrase family.


ensembl_gene_id: A0A0N4YJU6
symbol: NBR_LOCUS17263
gene_biotype: protein_coding
description:
  NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: A0A0N4YJV4
symbol: NBR_LOCUS17274
gene_biotype: protein_coding
description:
  Probable ubiquitin carboxyl-terminal hydrolase (inferred by orthology to a C. elegans protein); Belongs to the peptidase C19 family.


ensembl_gene_id: A0A0N4YJY2
symbol: NBR_LOCUS17308
gene_biotype: protein_coding
description:
  Carbonic anhydrase 4 (inferred by orthology to a human protein); Belongs to the alpha-carbonic anhydrase family.


ensembl_gene_id: A0A0N4YK76
symbol: NBR_LOCUS17425
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4YKB4
symbol: NBR_LOCUS17470
gene_biotype: protein_coding
description:
  Neutral alpha-glucosidase AB (inferred by orthology to a human protein); Belongs to the glycosyl hydrolase 31 family.


ensembl_gene_id: A0A0N4YKH1
symbol: NBR_LOCUS17540
gene_biotype: protein_coding
description:
  Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A0N4YKQ0
symbol: NBR_LOCUS17637
gene_biotype: protein_coding
description:
  rRNA 2'-O-methyltransferase fibrillarin (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: A0A0N4YL27
symbol: NBR_LOCUS17782
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.


ensembl_gene_id: A0A0N4YL86
symbol: NBR_LOCUS17851
gene_biotype: protein_coding
description:
  Thioredoxin reductase 1 (inferred by orthology to a C. elegans protein); Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: A0A0N4YLG0
symbol: NBR_LOCUS17948
gene_biotype: protein_coding
description:
  60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.


ensembl_gene_id: A0A0N4YLH3
symbol: NBR_LOCUS17963
gene_biotype: protein_coding
description:
  GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.


ensembl_gene_id: A0A0N4YLH8
symbol: NBR_LOCUS17969
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.


ensembl_gene_id: A0A0N4YLJ9
symbol: MED11
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4YLK1
symbol: NBR_LOCUS17995
gene_biotype: protein_coding
description:
  Chaperonin homolog Hsp-60, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the chaperonin (HSP60) family.


ensembl_gene_id: A0A0N4YLK3
symbol: NBR_LOCUS17997
gene_biotype: protein_coding
description:
  Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.


ensembl_gene_id: A0A0N4YLP3
symbol: NBR_LOCUS18042
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A0N4YLQ8
symbol: NBR_LOCUS18059
gene_biotype: protein_coding
description:
  Retinoid-inducible serine carboxypeptidase (inferred by orthology to a human protein); Belongs to the peptidase S10 family.


ensembl_gene_id: A0A0N4YLS2
symbol: NBR_LOCUS18074
gene_biotype: protein_coding
description:
  5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.


ensembl_gene_id: A0A0N4YLW3
symbol: NBR_LOCUS18124
gene_biotype: protein_coding
description:
  Tryptophan--tRNA ligase, cytoplasmic (inferred by orthology to a human protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4YLW8
symbol: NBR_LOCUS18129
gene_biotype: protein_coding
description:
  ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: A0A0N4YLW9
symbol: NBR_LOCUS18130
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily.


ensembl_gene_id: A0A0N4YM68
symbol: NBR_LOCUS18248
gene_biotype: protein_coding
description:
  Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.


ensembl_gene_id: A0A0N4YME4
symbol: NBR_LOCUS18339
gene_biotype: protein_coding
description:
  Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.


ensembl_gene_id: A0A0N4YME6
symbol: NBR_LOCUS18341
gene_biotype: protein_coding
description:
  DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.


ensembl_gene_id: A0A0N4YMF9
symbol: NBR_LOCUS18354
gene_biotype: protein_coding
description:
  Decaprenyl-diphosphate synthase subunit 1 (inferred by orthology to a human protein); Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: A0A0N4YMG9
symbol: NBR_LOCUS18365
gene_biotype: protein_coding
description:
  Cyclin-dependent kinase 5 (inferred by orthology to a human protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YML5
symbol: NBR_LOCUS18424
gene_biotype: protein_coding
description:
  GTP-binding protein SAR1 (inferred by orthology to a C. elegans protein); Belongs to the small GTPase superfamily. SAR1 family.


ensembl_gene_id: A0A0N4YMP3
symbol: NBR_LOCUS18458
gene_biotype: protein_coding
description:
  Methionine--tRNA ligase, mitochondrial (inferred by orthology to a human protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4YMT5
symbol: NBR_LOCUS18510
gene_biotype: protein_coding
description:
  Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family.


ensembl_gene_id: A0A0N4YNC2
symbol: NBR_LOCUS18729
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase cgh-1 (inferred by orthology to a C. elegans protein); Belongs to the DEAD box helicase family.


ensembl_gene_id: A0A0N4YNC5
symbol: NBR_LOCUS18732
gene_biotype: protein_coding
description:
  Trifunctional enzyme subunit alpha, mitochondrial (inferred by orthology to a human protein); Belongs to the nanos family.


ensembl_gene_id: A0A0N4YNE5
symbol: NBR_LOCUS18757
gene_biotype: protein_coding
description:
  Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: A0A0N4YNG1
symbol: NBR_LOCUS18776
gene_biotype: protein_coding
description:
  Cyclin-dependent kinase 7 (inferred by orthology to a human protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YNJ5
symbol: NBR_LOCUS18810
gene_biotype: protein_coding
description:
  Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: A0A0N4YNT2
symbol: NBR_LOCUS18903
gene_biotype: protein_coding
description:
  Tryptophan--tRNA ligase, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4YNV3
symbol: NBR_LOCUS18925
gene_biotype: protein_coding
description:
  Probable arginine--tRNA ligase, cytoplasmic (inferred by orthology to a C. elegans protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4YNZ3
symbol: NBR_LOCUS18965
gene_biotype: protein_coding
description:
  DNA repair protein RAD51 homolog 1 (inferred by orthology to a human protein); Belongs to the RecA family.


ensembl_gene_id: A0A0N4YP44
symbol: NBR_LOCUS19016
gene_biotype: protein_coding
description:
  SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.


ensembl_gene_id: A0A0N4YP51
symbol: NBR_LOCUS19024
gene_biotype: protein_coding
description:
  Hum-2 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A0N4YPM4
symbol: NBR_LOCUS19196
gene_biotype: protein_coding
description:
  Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family.


ensembl_gene_id: A0A0N4YPP6
symbol: NBR_LOCUS19218
gene_biotype: protein_coding
description:
  DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.


ensembl_gene_id: A0A0N4YPU8
symbol: NBR_LOCUS19270
gene_biotype: protein_coding
description:
  Mpv17-like protein (inferred by orthology to a C. elegans protein); Belongs to the peroxisomal membrane protein PXMP2/4 family.


ensembl_gene_id: A0A0N4YPV1
symbol: NBR_LOCUS19273
gene_biotype: protein_coding
description:
  Uncharacterized peptidase C1-like protein (inferred by orthology to a C. elegans protein); Belongs to the peptidase C1 family.


ensembl_gene_id: A0A0N4YPV3
symbol: NBR_LOCUS19275
gene_biotype: protein_coding
description:
  Acetylcholine receptor subunit alpha-type deg-3 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4YQ41
symbol: NBR_LOCUS19364
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase type-2 (inferred by orthology to a human protein); Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: A0A0N4YQ49
symbol: NBR_LOCUS19374
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.


ensembl_gene_id: A0A0N4YQ50
symbol: NBR_LOCUS19375
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.


ensembl_gene_id: A0A0N4YQ63
symbol: NBR_LOCUS19384
gene_biotype: protein_coding
description:
  G2/mitotic-specific cyclin-A (inferred by orthology to a D. melanogaster protein); Belongs to the cyclin family.


ensembl_gene_id: A0A0N4YQ64
symbol: NBR_LOCUS19385
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase, mitochondrial (inferred by orthology to a human protein); Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A0N4YQ72
symbol: NBR_LOCUS19395
gene_biotype: protein_coding
description:
  Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.


ensembl_gene_id: A0A0N4YQ73
symbol: NBR_LOCUS19396
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: A0A0N4YQ74
symbol: NBR_LOCUS19397
gene_biotype: protein_coding
description:
  Glutamate dehydrogenase, mitochondrial (inferred by orthology to a D. melanogaster protein); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: A0A0N4YQ93
symbol: NBR_LOCUS19416
gene_biotype: protein_coding
description:
  Elongation factor 1-beta (inferred by orthology to a human protein); Belongs to the EF-1-beta/EF-1-delta family.


ensembl_gene_id: A0A0N4YQC1
symbol: NBR_LOCUS19444
gene_biotype: protein_coding
description:
  Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates  [...]


ensembl_gene_id: A0A0N4YQE9
symbol: NBR_LOCUS19472
gene_biotype: protein_coding
description:
  Acetylcholine receptor subunit alpha-type des-2 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4YQL8
symbol: NBR_LOCUS19541
gene_biotype: protein_coding
description:
  Voltage-gated potassium channel, putative (inferred by orthology to a S. mansoni protein); Belongs to the potassium channel family.


ensembl_gene_id: A0A0N4YQR2
symbol: NBR_LOCUS19585
gene_biotype: protein_coding
description:
  G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.


ensembl_gene_id: A0A0N4YQT2
symbol: NBR_LOCUS19605
gene_biotype: protein_coding
description:
  Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.


ensembl_gene_id: A0A0N4YQT8
symbol: NBR_LOCUS19611
gene_biotype: protein_coding
description:
  Probable elongation factor 1-beta/1-delta 1 (inferred by orthology to a C. elegans protein); Belongs to the EF-1-beta/EF-1-delta family.


ensembl_gene_id: A0A0N4YQU3
symbol: NBR_LOCUS19616
gene_biotype: protein_coding
description:
  Acid phosphatase-like protein 2 (inferred by orthology to a human protein); Belongs to the histidine acid phosphatase family.


ensembl_gene_id: A0A0N4YQZ8
symbol: NBR_LOCUS19671
gene_biotype: protein_coding
description:
  Thioredoxin-related transmembrane protein 2 homolog (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A0N4YR62
symbol: NBR_LOCUS19735
gene_biotype: protein_coding
description:
  3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: A0A0N4YRF1
symbol: NBR_LOCUS19824
gene_biotype: protein_coding
description:
  Trifunctional enzyme subunit beta, mitochondrial (inferred by orthology to a human protein); Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A0N4YRK5
symbol: NBR_LOCUS19878
gene_biotype: protein_coding
description:
  Non-specific lipid-transfer protein (inferred by orthology to a human protein); Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: A0A0N4YRL6
symbol: NBR_LOCUS19889
gene_biotype: protein_coding
description:
  Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: A0A0N4YRS6
symbol: NBR_LOCUS19949
gene_biotype: protein_coding
description:
  Probable cyclin-dependent kinase 9 (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YS74
symbol: NBR_LOCUS20093
gene_biotype: protein_coding
description:
  Probable arginine--tRNA ligase, mitochondrial (inferred by orthology to a human protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A0N4YS78
symbol: NBR_LOCUS20101
gene_biotype: protein_coding
description:
  Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family.


ensembl_gene_id: A0A0N4YSJ9
symbol: NBR_LOCUS20222
gene_biotype: protein_coding
description:
  3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.


ensembl_gene_id: A0A0N4YSQ0
symbol: NBR_LOCUS20273
gene_biotype: protein_coding
description:
  Putative pachytene checkpoint protein 2 (inferred by orthology to a C. elegans protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A0N4YSS2
symbol: NBR_LOCUS20295
gene_biotype: protein_coding
description:
  Sulfite oxidase, mitochondrial (inferred by orthology to a human protein); Belongs to the cytochrome b5 family.


ensembl_gene_id: A0A0N4YSW0
symbol: NBR_LOCUS20331
gene_biotype: protein_coding
description:
  Glycine receptor subunit beta-type 4 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A0N4YT05
symbol: NBR_LOCUS20378
gene_biotype: protein_coding
description:
  Putative aspartyl aminopeptidase (inferred by orthology to a C. elegans protein); Belongs to the peptidase M18 family.


ensembl_gene_id: A0A0N4YT76
symbol: NBR_LOCUS20449
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: A0A0N4YTR8
symbol: NBR_LOCUS20641
gene_biotype: protein_coding
description:
  Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family.


ensembl_gene_id: A0A0N4YTW7
symbol: SRP54
gene_biotype: protein_coding
description:
  Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.


ensembl_gene_id: A0A0N4YTX3
symbol: NBR_LOCUS20696
gene_biotype: protein_coding
description:
  Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxid [...]


ensembl_gene_id: A0A0N4YU03
symbol: NBR_LOCUS20726
gene_biotype: protein_coding
description:
  Alpha-(1,6)-fucosyltransferase (inferred by orthology to a human protein); Belongs to the glycosyltransferase 23 family.


ensembl_gene_id: A0A0N4YU59
symbol: NBR_LOCUS20782
gene_biotype: protein_coding
description:
  Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]


ensembl_gene_id: A0A0N4YUF1
symbol: NBR_LOCUS20874
gene_biotype: protein_coding
description:
  Fatty acid binding protein, putative (inferred by orthology to a S. mansoni protein); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A0N4YUF5
symbol: NBR_LOCUS20878
gene_biotype: protein_coding
description:
  Diacylglycerol O-acyltransferase 1 (inferred by orthology to a human protein); Belongs to the membrane-bound acyltransferase family.


ensembl_gene_id: A0A0N4YUF9
symbol: NBR_LOCUS20882
gene_biotype: protein_coding
description:
  10 kDa heat shock protein, mitochondrial (inferred by orthology to a human protein); Belongs to the GroES chaperonin family.


ensembl_gene_id: A0A0N4YUR0
symbol: NBR_LOCUS20983
gene_biotype: protein_coding
description:
  Adenylate cyclase type 2 (inferred by orthology to a D. melanogaster protein); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A0N4YUY2
symbol: NBR_LOCUS21055
gene_biotype: protein_coding
description:
  Cation_ATPase_C domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.


ensembl_gene_id: A0A0N4YUZ5
symbol: NBR_LOCUS21068
gene_biotype: protein_coding
description:
  Probable ornithine aminotransferase, mitochondrial (inferred by orthology to a C. elegans protein); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: A0A0N4YVA8
symbol: NBR_LOCUS21181
gene_biotype: protein_coding
description:
  Eukaryotic initiation factor 4A-III (inferred by orthology to a human protein); Belongs to the DEAD box helicase family.


ensembl_gene_id: A0A0N4YVD6
symbol: NBR_LOCUS21209
gene_biotype: protein_coding
description:
  KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.


ensembl_gene_id: A0A0N4YVE0
symbol: NBR_LOCUS21213
gene_biotype: protein_coding
description:
  Serine/threonine protein kinase (inferred by orthology to a S. mansoni protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YVL9
symbol: LSM8
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: A0A0N4YVZ6
symbol: NBR_LOCUS21419
gene_biotype: protein_coding
description:
  Probable cytochrome P450 CYP36A1 (inferred by orthology to a C. elegans protein); Belongs to the cytochrome P450 family.


ensembl_gene_id: A0A0N4YW03
symbol: NBR_LOCUS21426
gene_biotype: protein_coding
description:
  Sugar transporter SWEET; Mediates sugar transport across membranes. Belongs to the SWEET sugar transporter family.


ensembl_gene_id: A0A0N4YW19
symbol: NBR_LOCUS21442
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.


ensembl_gene_id: A0A0N4YW29
symbol: NBR_LOCUS21452
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 2 (inferred by orthology to a C. elegans protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A0N4YXE7
symbol: NBR_LOCUS21920
gene_biotype: protein_coding
description:
  Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.


ensembl_gene_id: A0A0N4YXM3
symbol: NBR_LOCUS21996
gene_biotype: protein_coding
description:
  Disks large 1 tumor suppressor protein (inferred by orthology to a D. melanogaster protein); Belongs to the MAGUK family.


ensembl_gene_id: A0A0N4YXN0
symbol: NBR_LOCUS22003
gene_biotype: protein_coding
description:
  Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.


ensembl_gene_id: A0A0N4YXZ2
symbol: NBR_LOCUS22115
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.


ensembl_gene_id: A0A0N4YY69
symbol: NBR_LOCUS22194
gene_biotype: protein_coding
description:
  Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.


ensembl_gene_id: A0A0N4YYI9
symbol: NBR_LOCUS22312
gene_biotype: protein_coding
description:
  40S ribosomal protein S5 (inferred by orthology to a human protein); Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: A0A0N4YZP8
symbol: NBR_LOCUS22721
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase Warts (inferred by orthology to a D. melanogaster protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A0N4YZT3
symbol: NBR_LOCUS22756
gene_biotype: protein_coding
description:
  ADP-ribosylation factor 1 (inferred by orthology to a D. melanogaster protein); Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: A0A158QWJ0
symbol: NBR_LOCUS290
gene_biotype: protein_coding
description:
  NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.


ensembl_gene_id: A0A158QWL6
symbol: NBR_LOCUS450
gene_biotype: protein_coding
description:
  Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A158QWL8
symbol: NBR_LOCUS462
gene_biotype: protein_coding
description:
  Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.


ensembl_gene_id: A0A158QWP0
symbol: NBR_LOCUS632
gene_biotype: protein_coding
description:
  Lamin-1 (inferred by orthology to a C. elegans protein); Belongs to the intermediate filament family.


ensembl_gene_id: A0A158QWP3
symbol: NBR_LOCUS5621
gene_biotype: protein_coding
description:
  Degenerin del-1 (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A158QWQ7
symbol: NBR_LOCUS5669
gene_biotype: protein_coding
description:
  Soluble guanylate cyclase gcy-36 (inferred by orthology to a C. elegans protein); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.


ensembl_gene_id: A0A158QWR3
symbol: NBR_LOCUS5687
gene_biotype: protein_coding
description:
  Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.


ensembl_gene_id: A0A158QWY6
symbol: NBR_LOCUS5980
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 N (inferred by orthology to a D. melanogaster protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A158QX08
symbol: NBR_LOCUS6081
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.


ensembl_gene_id: A0A158QX25
symbol: NBR_LOCUS6146
gene_biotype: protein_coding
description:
  Putative carbonic anhydrase 5 (inferred by orthology to a C. elegans protein); Belongs to the alpha-carbonic anhydrase family.


ensembl_gene_id: A0A158QX48
symbol: NBR_LOCUS6215
gene_biotype: protein_coding
description:
  Dynamin-1-like protein (inferred by orthology to a human protein); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: A0A158QX58
symbol: NBR_LOCUS6267
gene_biotype: protein_coding
description:
  Degenerin mec-4 (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A158QX96
symbol: NBR_LOCUS6483
gene_biotype: protein_coding
description:
  Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.


ensembl_gene_id: A0A158QXC4
symbol: NBR_LOCUS6618
gene_biotype: protein_coding
description:
  Uncoordinated protein 58 (inferred by orthology to a C. elegans protein); Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A158QXC7
symbol: NBR_LOCUS6624
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: A0A158QXD1
symbol: NBR_LOCUS6638
gene_biotype: protein_coding
description:
  EGL-17 (inferred by orthology to a C. elegans protein); Belongs to the heparin-binding growth factors family.


ensembl_gene_id: A0A158QXE5
symbol: NBR_LOCUS6724
gene_biotype: protein_coding
description:
  Choline transporter-like protein 1 (inferred by orthology to a C. elegans protein); Belongs to the CTL (choline transporter-like) family.


ensembl_gene_id: A0A158QXH0
symbol: NBR_LOCUS6820
gene_biotype: protein_coding
description:
  10-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.


ensembl_gene_id: A0A158QXL2
symbol: NBR_LOCUS7042
gene_biotype: protein_coding
description:
  Casein kinase II subunit alpha (inferred by orthology to a C. elegans protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A158QXR7
symbol: NBR_LOCUS7280
gene_biotype: protein_coding
description:
  Cadherin-related hmr-1 (inferred by orthology to a C. elegans protein); Cadherins are calcium-dependent cell adhesion proteins.


ensembl_gene_id: A0A158QXS6
symbol: NBR_LOCUS7326
gene_biotype: protein_coding
description:
  Acetolactate synthase-like protein (inferred by orthology to a C. elegans protein); Belongs to the TPP enzyme family.


ensembl_gene_id: A0A158QXV3
symbol: MED10
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: A0A158QXV8
symbol: NBR_LOCUS7499
gene_biotype: protein_coding
description:
  Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family.


ensembl_gene_id: A0A158QXX4
symbol: NBR_LOCUS7562
gene_biotype: protein_coding
description:
  GDP-L-fucose synthase (inferred by orthology to a human protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A158QY25
symbol: NBR_LOCUS7785
gene_biotype: protein_coding
description:
  Transitional endoplasmic reticulum ATPase (inferred by orthology to a human protein); Belongs to the AAA ATPase family.


ensembl_gene_id: A0A158QY92
symbol: NBR_LOCUS8106
gene_biotype: protein_coding
description:
  60S ribosomal protein L3 (inferred by orthology to a C. elegans protein); Belongs to the universal ribosomal protein uL3 family.


ensembl_gene_id: A0A158QY95
symbol: NBR_LOCUS8117
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: A0A158QYA0
symbol: NBR_LOCUS8135
gene_biotype: protein_coding
description:
  SUMO-conjugating enzyme UBC9 (inferred by orthology to a C. elegans protein); Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: A0A158QYC6
symbol: NBR_LOCUS8282
gene_biotype: protein_coding
description:
  Ligand-gated ion channel 4 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A158QYC8
symbol: NBR_LOCUS8289
gene_biotype: protein_coding
description:
  Acetylcholine-gated chloride channel subunit ACC-3 (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A158QYD8
symbol: NBR_LOCUS8327
gene_biotype: protein_coding
description:
  DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.


ensembl_gene_id: A0A158QYG3
symbol: NBR_LOCUS8451
gene_biotype: protein_coding
description:
  Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.


ensembl_gene_id: A0A158QYG5
symbol: NBR_LOCUS8463
gene_biotype: protein_coding
description:
  Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family.


ensembl_gene_id: A0A158QYI0
symbol: NBR_LOCUS8516
gene_biotype: protein_coding
description:
  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.


ensembl_gene_id: A0A158QYJ7
symbol: NBR_LOCUS8594
gene_biotype: protein_coding
description:
  Regulator of telomere elongation helicase 1 homolog (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A158QYL0
symbol: NBR_LOCUS8665
gene_biotype: protein_coding
description:
  Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.


ensembl_gene_id: A0A158QYP3
symbol: NBR_LOCUS8780
gene_biotype: protein_coding
description:
  Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.


ensembl_gene_id: A0A158QYP9
symbol: NBR_LOCUS8811
gene_biotype: protein_coding
description:
  Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: A0A158QYT0
symbol: NBR_LOCUS8972
gene_biotype: protein_coding
description:
  Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.


ensembl_gene_id: A0A158QYU9
symbol: NBR_LOCUS9061
gene_biotype: protein_coding
description:
  AP-2 complex subunit mu (inferred by orthology to a C. elegans protein); Belongs to the adaptor complexes medium subunit family.


ensembl_gene_id: A0A158QYY8
symbol: NBR_LOCUS9217
gene_biotype: protein_coding
description:
  Guanine nucleotide-binding protein alpha-13 subunit (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A158QYZ2
symbol: NBR_LOCUS9232
gene_biotype: protein_coding
description:
  Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.


ensembl_gene_id: A0A158QZ21
symbol: NBR_LOCUS9399
gene_biotype: protein_coding
description:
  Degenerin deg-1 (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A158QZ23
symbol: NBR_LOCUS9412
gene_biotype: protein_coding
description:
  Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.


ensembl_gene_id: A0A158QZ41
symbol: NBR_LOCUS9523
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.


ensembl_gene_id: A0A158QZ57
symbol: NBR_LOCUS9597
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the DHHC palmitoyltransferase family.


ensembl_gene_id: A0A158QZ80
symbol: NBR_LOCUS9713
gene_biotype: protein_coding
description:
  Putative SMARCAL1-like protein (inferred by orthology to a C. elegans protein); Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.


ensembl_gene_id: A0A158QZ83
symbol: NBR_LOCUS9723
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase 64E (inferred by orthology to a D. melanogaster protein); Belongs to the peptidase C19 family.


ensembl_gene_id: A0A158QZA4
symbol: NBR_LOCUS9807
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.


ensembl_gene_id: A0A158QZI0
symbol: NBR_LOCUS10168
gene_biotype: protein_coding
description:
  RNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs; Belongs to the RtcB family.


ensembl_gene_id: A0A158QZI2
symbol: NTH1
gene_biotype: protein_coding
description:
  Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.


ensembl_gene_id: A0A158QZJ0
symbol: NBR_LOCUS10200
gene_biotype: protein_coding
description:
  Glutamate-gated chloride channel subunit (inferred by orthology to a C. elegans protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A158QZL0
symbol: NBR_LOCUS10311
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase (inferred by orthology to a C. elegans protein); Belongs to the DEAD box helicase family.


ensembl_gene_id: A0A158QZP8
symbol: NBR_LOCUS10485
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.


ensembl_gene_id: A0A158QZP9
symbol: NBR_LOCUS10489
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.


ensembl_gene_id: A0A158QZV7
symbol: NBR_LOCUS10793
gene_biotype: protein_coding
description:
  Mitochondrial coenzyme A transporter SLC25A42 (inferred by orthology to a human protein); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: A0A158QZW8
symbol: NBR_LOCUS10841
gene_biotype: protein_coding
description:
  Probable phosphoribosylformylglycinamidine synthase (inferred by orthology to a C. elegans protein).


ensembl_gene_id: A0A158QZX2
symbol: NBR_LOCUS10863
gene_biotype: protein_coding
description:
  Putative acid phosphatase 1 (inferred by orthology to a C. elegans protein); Belongs to the histidine acid phosphatase family.


ensembl_gene_id: A0A158QZX3
symbol: NBR_LOCUS10865
gene_biotype: protein_coding
description:
  Kinesin-like protein vab-8 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A158R042
symbol: NBR_LOCUS11178
gene_biotype: protein_coding
description:
  Mitogen-activated protein kinase 7 (inferred by orthology to a human protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A158R051
symbol: NBR_LOCUS11208
gene_biotype: protein_coding
description:
  Probable exosome complex exonuclease RRP44 (inferred by orthology to a C. elegans protein); Belongs to the RNR ribonuclease family.


ensembl_gene_id: A0A158R054
symbol: NBR_LOCUS11213
gene_biotype: protein_coding
description:
  UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: A0A158R073
symbol: NBR_LOCUS11303
gene_biotype: protein_coding
description:
  CCA tRNA nucleotidyltransferase 1, mitochondrial (inferred by orthology to a human protein); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: A0A158R082
symbol: NBR_LOCUS11340
gene_biotype: protein_coding
description:
  Kinesin-like protein unc-104 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: A0A158R0C9
symbol: NBR_LOCUS11564
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A158R0E7
symbol: NBR_LOCUS11682
gene_biotype: protein_coding
description:
  Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3.


ensembl_gene_id: A0A158R0L7
symbol: NBR_LOCUS12071
gene_biotype: protein_coding
description:
  Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.


ensembl_gene_id: A0A158R0M4
symbol: NBR_LOCUS12123
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...]


ensembl_gene_id: A0A158R0P6
symbol: NBR_LOCUS12269
gene_biotype: protein_coding
description:
  Transient-receptor-potential-like protein (inferred by orthology to a C. elegans protein); Belongs to the transient receptor (TC 1.A.4) family.


ensembl_gene_id: A0A158R0S0
symbol: KATNA1
gene_biotype: protein_coding
description:
  Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.


ensembl_gene_id: A0A158R0S8
symbol: NBR_LOCUS12469
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (inferred by orthology to a human protein); Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: A0A158R0V0
symbol: NBR_LOCUS12586
gene_biotype: protein_coding
description:
  Glutamate receptor ionotropic, NMDA 1 (inferred by orthology to a human protein); Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.


ensembl_gene_id: A0A158R0W4
symbol: NBR_LOCUS12666
gene_biotype: protein_coding
description:
  Fatty acid-binding protein homolog 9 (inferred by orthology to a C. elegans protein); Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.


ensembl_gene_id: A0A158R123
symbol: NBR_LOCUS12987
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: A0A158R176
symbol: NBR_LOCUS13243
gene_biotype: protein_coding
description:
  Myosin heavy chain-like (inferred by orthology to a D. melanogaster protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A158R191
symbol: NBR_LOCUS13309
gene_biotype: protein_coding
description:
  Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.


ensembl_gene_id: A0A158R1I5
symbol: NBR_LOCUS13863
gene_biotype: protein_coding
description:
  Degenerin-like protein unc-105 (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A158R1I7
symbol: NBR_LOCUS13884
gene_biotype: protein_coding
description:
  TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.


ensembl_gene_id: A0A158R1I8
symbol: NBR_LOCUS13891
gene_biotype: protein_coding
description:
  Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.


ensembl_gene_id: A0A158R1L3
symbol: NBR_LOCUS13986
gene_biotype: protein_coding
description:
  Probable muscarinic acetylcholine receptor gar-1 (inferred by orthology to a C. elegans protein); Belongs to the G-protein coupled receptor 1 family.


ensembl_gene_id: A0A158R1Q1
symbol: NBR_LOCUS14215
gene_biotype: protein_coding
description:
  Calcium/calmodulin-dependent protein kinase I (inferred by orthology to a D. melanogaster protein); Belongs to the protein kinase superfamily.


ensembl_gene_id: A0A158R1W5
symbol: NBR_LOCUS14570
gene_biotype: protein_coding
description:
  Ornithine decarboxylase (inferred by orthology to a C. elegans protein); Belongs to the Orn/Lys/Arg decarboxylase class-II family.


ensembl_gene_id: A0A158R1Z6
symbol: NBR_LOCUS14748
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: A0A158R213
symbol: NBR_LOCUS14808
gene_biotype: protein_coding
description:
  Aspartic protease 3 (inferred by orthology to a C. elegans protein); Belongs to the peptidase A1 family.


ensembl_gene_id: A0A158R240
symbol: NBR_LOCUS15019
gene_biotype: protein_coding
description:
  Choline O-acetyltransferase (inferred by orthology to a C. elegans protein); Belongs to the carnitine/choline acetyltransferase family.


ensembl_gene_id: A0A158R249
symbol: NBR_LOCUS15068
gene_biotype: protein_coding
description:
  NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.


ensembl_gene_id: A0A158R273
symbol: NBR_LOCUS15166
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family.


ensembl_gene_id: A0A158R2B8
symbol: NBR_LOCUS15494
gene_biotype: protein_coding
description:
  CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.


ensembl_gene_id: A0A158R2C2
symbol: NBR_LOCUS15520
gene_biotype: protein_coding
description:
  Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex  [...]


ensembl_gene_id: A0A158R2C8
symbol: NBR_LOCUS15579
gene_biotype: protein_coding
description:
  Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.


ensembl_gene_id: A0A158R2G9
symbol: NBR_LOCUS15865
gene_biotype: protein_coding
description:
  Gamma-aminobutyric acid receptor subunit beta (inferred by orthology to a D. melanogaster protein); Belongs to the ligand-gated ion channel (TC 1.A.9) family.


ensembl_gene_id: A0A158R2I6
symbol: NBR_LOCUS16032
gene_biotype: protein_coding
description:
  Growth hormone-inducible transmembrane protein (inferred by orthology to a human protein); Belongs to the BI1 family.


ensembl_gene_id: A0A158R2J7
symbol: NBR_LOCUS16126
gene_biotype: protein_coding
description:
  Myosin-2 (inferred by orthology to a C. elegans protein); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: A0A158R2K3
symbol: NBR_LOCUS16179
gene_biotype: protein_coding
description:
  Degenerin-like protein (inferred by orthology to a C. elegans protein); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.


ensembl_gene_id: A0A158R2K8
symbol: NBR_LOCUS16230
gene_biotype: protein_coding
description:
  Probable glutamine--tRNA ligase (inferred by orthology to a C. elegans protein); Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: A0A158R2T0
symbol: NBR_LOCUS16750
gene_biotype: protein_coding
description:
  Putative syntaxin-5 (inferred by orthology to a C. elegans protein); Belongs to the syntaxin family.


ensembl_gene_id: A0A158R2T1
symbol: NBR_LOCUS16764
gene_biotype: protein_coding
description:
  Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs.


ensembl_gene_id: A0A158R2X0
symbol: NBR_LOCUS17078
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 4E-3 (inferred by orthology to a C. elegans protein); Belongs to the eukaryotic initiation factor 4E family.


ensembl_gene_id: A0A158R332
symbol: NBR_LOCUS17417
gene_biotype: protein_coding
description:
  Rhomboid-related protein 1 (inferred by orthology to a C. elegans protein); Belongs to the peptidase S54 family.


ensembl_gene_id: A0A158R333
symbol: NBR_LOCUS17423
gene_biotype: protein_coding
description:
  TWiK family of potassium channels protein 12 (inferred by orthology to a C. elegans protein); Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.


ensembl_gene_id: A0A158R343
symbol: NBR_LOCUS17503
gene_biotype: protein_coding
description:
  Neuferricin homolog (inferred by orthology to a C. elegans protein); Belongs to the cytochrome b5 family.


ensembl_gene_id: A0A158R396
symbol: NBR_LOCUS17834
gene_biotype: protein_coding
description:
  Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.


ensembl_gene_id: A0A158R3A6
symbol: NBR_LOCUS17878
gene_biotype: protein_coding
description:
  Integrin alpha pat-2 (inferred by orthology to a C. elegans protein); Belongs to the integrin alpha chain family.


ensembl_gene_id: A0A158R3B8
symbol: NBR_LOCUS17925
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.


ensembl_gene_id: A0A158R3N2
symbol: NBR_LOCUS18638
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: A0A3P7A219
symbol: NBR_LOCUS785
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.


ensembl_gene_id: A0A3P7AGC5
symbol: NBR_LOCUS1419
gene_biotype: protein_coding
description:
  RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: A0A3P7APQ8
symbol: NBR_LOCUS4494
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.


ensembl_gene_id: A0A3P7B0D2
symbol: NBR_LOCUS8744
gene_biotype: protein_coding
description:
  MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: A0A3P7B6R7
symbol: NBR_LOCUS13977
gene_biotype: protein_coding
description:
  Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.


ensembl_gene_id: A0A3P7D6Q0
symbol: NBR_LOCUS19771
gene_biotype: protein_coding
description:
  Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


