# pathwayInfo

id: SM00559
description: Ku70 and Ku80 are 70kDa and 80kDa subunits of the Lupus Ku autoantigen
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00559
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00559_Ku70_and_Ku80_are_70kDa_and_80kDa_subunits_of_the_Lupus_Ku_autoantigen


id: SM00562
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00562
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00562_These_are_enzymes_that_catalyze_nonsubstrate_specific_conversions_of_nucleoside_diphosphates_to_nucleoside_triphosphates._These_enzymes_play_important_roles_in_bacterial_growth,_signal_transduction_and_pathogenicity.

description:
  These are enzymes that catalyze nonsubstrate specific conversions of nucleoside diphosphates to nucleoside triphosphates. These enzymes play important roles in bacterial growth, signal transduction and pathogenicity.


id: SM00568
description: Domain in glucosyltransferases, myotubularins and other putative membrane-associated proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00568
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00568_Domain_in_glucosyltransferases,_myotubularins_and_other_putative_membrane-associated_proteins


id: SM00573
description: Domain in helicases and associated with SANT domains
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00573
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00573_Domain_in_helicases_and_associated_with_SANT_domains


id: SM00576
description: Bromodomain transcription factors and PHD domain containing proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00576
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00576_Bromodomain_transcription_factors_and_PHD_domain_containing_proteins


id: SM00577
description: Catalytic domain of ctd-like phosphatases
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00577
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00577_Catalytic_domain_of_ctd-like_phosphatases


id: SM00580
description: Domain in protein kinases, N-glycanases and other nuclear proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00580
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00580_Domain_in_protein_kinases,_N-glycanases_and_other_nuclear_proteins


id: SM00581
description: Proline-rich domain in spliceosome associated proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00581
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00581_Proline-rich_domain_in_spliceosome_associated_proteins


id: SM00582
description: Domain present in proteins, which are involved in regulation of nuclear pre-mRNA
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00582
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00582_Domain_present_in_proteins,_which_are_involved_in_regulation_of_nuclear_pre-mRNA


id: SM00584
description: Domain in TBC and LysM domain containing proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00584
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00584_Domain_in_TBC_and_LysM_domain_containing_proteins


id: SM00591
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00591
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00591_Domain_in_RING_finger_and_WD_repeat_containing_proteins_and_DEXDc-like_helicases_subfamily_related_to_the_UBCc_domain

description:
  Domain in RING finger and WD repeat containing proteins and DEXDc-like helicases subfamily related to the UBCc domain


id: SM00648
description: Suppressor-of-White-APricot splicing regulator
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00648
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00648_Suppressor-of-White-APricot_splicing_regulator


id: SM00652
description: Eukaryotic translation initiation factor 1A
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00652
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00652_Eukaryotic_translation_initiation_factor_1A


id: SM00653
description: Domain present in translation initiation factor eIF2B and eIF5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00653
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00653_Domain_present_in_translation_initiation_factor_eIF2B_and_eIF5


id: SM00667
description: Lissencephaly type-1-like homology motif
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00667
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00667_Lissencephaly_type-1-like_homology_motif


id: SM00670
description: Large family of predicted nucleotide-binding domains
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00670
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00670_Large_family_of_predicted_nucleotide-binding_domains


id: SM00673
description: Domain in CAPs (cyclase-associated proteins) and X-linked retinitis pigmentosa 2 gene product.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00673
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00673_Domain_in_CAPs_(cyclase-associated_proteins)_and_X-linked_retinitis_pigmentosa_2_gene_product.


id: SM00674
description: Putative DNA-binding domain in centromere protein B, mouse jerky and transposases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00674
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00674_Putative_DNA-binding_domain_in_centromere_protein_B,_mouse_jerky_and_transposases.


id: SM00679
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00679
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00679_Repeated_motif_present_between_transmembrane_helices_in_cystinosin,_yeast_ERS1p,_mannose-P-dolichol_utilization_defect_1,_and_other_hypothetical_proteins.

description:
  Repeated motif present between transmembrane helices in cystinosin, yeast ERS1p, mannose-P-dolichol utilization defect 1, and other hypothetical proteins.


id: SM00695
description: Domain in ubiquitin-specific proteases.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00695
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00695_Domain_in_ubiquitin-specific_proteases.


id: SM00702
description: Prolyl 4-hydroxylase alpha subunit homologues.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00702
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00702_Prolyl_4-hydroxylase_alpha_subunit_homologues.


id: SM00709
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00709
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00709_Duplicated_domain_in_the_epidermal_growth_factor-_and_elongation_factor-1alpha-binding_protein_Zpr1._Also_present_in_archaeal_proteins.

description:
  Duplicated domain in the epidermal growth factor- and elongation factor-1alpha-binding protein Zpr1. Also present in archaeal proteins.


id: SM00715
description: Domain in the RNA-binding Lupus La protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00715
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00715_Domain_in_the_RNA-binding_Lupus_La_protein


id: SM00717
description: SANT SWI3, ADA2, N-CoR and TFIIIB DNA-binding domains
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00717
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00717_SANT__SWI3,_ADA2,_N-CoR_and_TFIIIB_DNA-binding_domains


id: SM00719
description: Short conserved domain in transcriptional regulators.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00719
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00719_Short_conserved_domain_in_transcriptional_regulators.


id: SM00729
description: Elongator protein 3, MiaB family, Radical SAM
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00729
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00729_Elongator_protein_3,_MiaB_family,_Radical_SAM


id: SM00730
description: Presenilin, signal peptide peptidase, family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00730
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00730_Presenilin,_signal_peptide_peptidase,_family


id: SM00737
description: Domain involved in innate immunity and lipid metabolism.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00737
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00737_Domain_involved_in_innate_immunity_and_lipid_metabolism.


id: SM00738
description: In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00738
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00738_In_Spt5p,_this_domain_may_confer_affinity_for_Spt4p._It_possesses_a_RNP-like_fold.


id: SM00742
description: Rho effector or protein kinase C-related kinase homology region 1 homologues
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00742
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00742_Rho_effector_or_protein_kinase_C-related_kinase_homology_region_1_homologues


id: SM00744
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00744
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00744_The_RING-variant_domain_is_a_C4HC3_zinc-finger_like_motif_found_in_a_number_of_cellular_and_viral_proteins._Some_of_these_proteins_have_been_shown_both_in_vivo_and_in_vitro_to_have_ubiquitin_E3_ligase_activity.

description:
  The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.


id: SM00745
description: Microtubule Interacting and Trafficking molecule domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00745
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00745_Microtubule_Interacting_and_Trafficking_molecule_domain


id: SM00751
description: Domain in transcription factors and synapse-associated proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00751
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00751_Domain_in_transcription_factors_and_synapse-associated_proteins


id: SM00755
description: golgin-97, RanBP2alpha,Imh1p and p230/golgin-245
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00755
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00755_golgin-97,_RanBP2alpha,Imh1p_and_p230/golgin-245


id: SM00758
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00758
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00758_Domain_in_bacterial_beta-glucosidases_other_glycosidases,_glycosyltransferases,_proteases,_amidases,_yeast_adhesins,_and_bacterial_toxins.

description:
  Domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins.


id: SM00768
description: Possibly involved in carbohydrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00768
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00768_Possibly_involved_in_carbohydrate_binding


id: SM00775
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00775
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00775_This_domain_is_found_in_Saccharomyces_cerevisiae_protein_SMP2,_proteins_with_an_N-terminal_lipin_domain_and_phosphatidylinositol_transfer_proteins._SMP2_is_involved_in_plasmid_maintenance_and_respiration._Lipin_proteins_are_involved_in_adipose_tissue_...

description:
  This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins. SMP2 is involved in plasmid maintenance and respiration. Lipin proteins are involved in adipose tissue ...


id: SM00777
description: Mad3/BUB1 hoMad3/BUB1 homology region 1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00777
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00777_Mad3/BUB1_hoMad3/BUB1_homology_region_1


id: SM00799
description: Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00799
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00799_Domain_found_in_a_variety_of_signalling_proteins,_always_encircled_by_uDENN_and_dDENN


id: SM00800
description: Domain always found upstream of DENN domain, found in a variety of signalling proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00800
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00800_Domain_always_found_upstream_of_DENN_domain,_found_in_a_variety_of_signalling_proteins


id: SM00801
description: Domain always found downstream of DENN domain, found in a variety of signalling proteins
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00801
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00801_Domain_always_found_downstream_of_DENN_domain,_found_in_a_variety_of_signalling_proteins


id: SM00802
description: Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00802
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00802_Domain_in_UVSB_PI-3_kinase,_MEI-41_and_ESR-1


id: SM00803
description: TATA box binding protein associated factor
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00803
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00803_TATA_box_binding_protein_associated_factor


id: SM00804
description: C-terminal domain of vertebrate Tap protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00804
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00804_C-terminal_domain_of_vertebrate_Tap_protein


id: SM00833
description: Cobalamin synthesis protein cobW C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00833
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00833_Cobalamin_synthesis_protein_cobW_C-terminal_domain


id: SM00839
description: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00839
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00839_Glutamate/Leucine/Phenylalanine/Valine_dehydrogenase


id: SM00846
description: Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00846
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00846_Glyceraldehyde_3-phosphate_dehydrogenase,_NAD_binding_domain


id: SM00847
description: Helicase associated domain (HA2) Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00847
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00847_Helicase_associated_domain_(HA2)__Add_an_annotation


id: SM00859
description: Semialdehyde dehydrogenase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00859
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00859_Semialdehyde_dehydrogenase,_NAD_binding_domain


id: SM00861
description: Transketolase, pyrimidine binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00861
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00861_Transketolase,_pyrimidine_binding_domain


id: SM00863
description: Threonyl and Alanyl tRNA synthetase second additional domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00863
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00863_Threonyl_and_Alanyl_tRNA_synthetase_second_additional_domain


id: SM00870
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00870
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00870_Asparaginase,_which_is_found_in_various_plant,_animal_and_bacterial_cells,_catalyses_the_deamination_of_asparagine_to_yield_aspartic_acid_and_an_ammonium_ion,_resulting_in_a_depletion_of_free_circulatory_asparagine_in_plasma_PUBMED:3026924._The_...

description:
  Asparaginase, which is found in various plant, animal and bacterial cells, catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion, resulting in a depletion of free circulatory asparagine in plasma PUBMED:3026924. The ...


id: SM00876
description: Biotin and Thiamin Synthesis associated domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00876
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00876_Biotin_and_Thiamin_Synthesis_associated_domain


id: SM00879
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00879
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00879_The_Brix_domain_is_found_in_a_number_of_eukaryotic_proteins_including_SSF_proteins_from_yeast_and_humans,_Arabidopsis_thaliana_Peter_Pan-like_protein_and_several_hypothetical_proteins.

description:
  The Brix domain is found in a number of eukaryotic proteins including SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.


id: SM00888
description: EF-1 guanine nucleotide exchange domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00888
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00888_EF-1_guanine_nucleotide_exchange_domain


id: SM00896
description: Ferredoxin-fold anticodon binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00896
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00896_Ferredoxin-fold_anticodon_binding_domain


id: SM00906
description: Fungal specific transcription factor domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00906
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00906_Fungal_specific_transcription_factor_domain


id: SM00910
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00910
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00910_The_HIRAN_protein_(HIP116,_Rad5p_N-terminal)_is_found_in_the_N-terminal_regions_of_the_SWI2/SNF2_proteins_typified_by_HIP116_and_Rad5p._HIRAN_is_found_as_a_standalone_protein_in_several_bacteria_and_prophages,_or_fused_to_other_catalytic_domains,_...

description:
  The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p. HIRAN is found as a standalone protein in several bacteria and prophages, or fused to other catalytic domains, ...


id: SM00916
description: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00916
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00916_Mitochondrial_ribosomal_protein_L51_/_S25_/_CI-B8_domain


id: SM00928
description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00928
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00928_NADH-ubiquinone_oxidoreductase-F_iron-sulfur_binding_region


id: SM00934
description: Orotidine 5-phosphate decarboxylase / HUMPS family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00934
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00934_Orotidine_5-phosphate_decarboxylase_/_HUMPS_family


id: SM00937
description: This domain is found in peptide chain release factors.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00937
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00937_This_domain_is_found_in_peptide_chain_release_factors.


id: SM00948
description: Proteasome subunit A N-terminal signature Add an annotation
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00948
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00948_Proteasome_subunit_A_N-terminal_signature__Add_an_annotation


id: SM00949
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00949
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00949_This_domain_is_named_PAZ_after_the_proteins_Piwi_Argonaut_and_Zwille._This_domain_is_found_in_two_families_of_proteins_that_are_involved_in_post-transcriptional_gene_silencing._These_are_the_Piwi_family_and_the_Dicer_family,_that_includes_the_Carpel_...

description:
  This domain is named PAZ after the proteins Piwi Argonaut and Zwille. This domain is found in two families of proteins that are involved in post-transcriptional gene silencing. These are the Piwi family and the Dicer family, that includes the Carpel ...


id: SM00950
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00950
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00950_This_domain_is_found_in_the_protein_Piwi_and_its_relatives._The_function_of_this_domain_is_the_dsRNA_guided_hydrolysis_of_ssRNA._Determination_of_the_crystal_structure_of_Argonaute_reveals_that_PIWI_is_an_RNase_H_domain,_and_identifies_Argonaute_as_...

description:
  This domain is found in the protein Piwi and its relatives. The function of this domain is the dsRNA guided hydrolysis of ssRNA. Determination of the crystal structure of Argonaute reveals that PIWI is an RNase H domain, and identifies Argonaute as ...


id: SM00951
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00951
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00951_QLQ_is_named_after_the_conserved_Gln,_Leu,_Gln_motif._QLQ_is_found_at_the_N-terminus_of_SWI2/SNF2_protein,_which_has_been_shown_to_be_involved_in_protein-protein_interactions._QLQ_has_been_postulated_to_be_involved_in_mediating_protein_interactions_...

description:
  QLQ is named after the conserved Gln, Leu, Gln motif. QLQ is found at the N-terminus of SWI2/SNF2 protein, which has been shown to be involved in protein-protein interactions. QLQ has been postulated to be involved in mediating protein interactions ...


id: SM00955
description: This domain is the catalytic domain of ribonuclease II.PUBMED:16806266
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00955
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00955_This_domain_is_the_catalytic_domain_of_ribonuclease_II.PUBMED:16806266


id: SM00956
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00956
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00956_This_DNA-binding_domain_is_found_in_the_RecQ_helicase_among_others_and_has_a_helix-turn-helix_structure._The_RQC_domain,_found_only_in_RecQ_family_enzymes,_is_a_high_affinity_G4_DNA_binding_domain_PUBMED:16530788.

description:
  This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain PUBMED:16530788.


id: SM00963
description: SRP54-type protein, helical bundle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00963
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00963_SRP54-type_protein,_helical_bundle_domain


id: SM00967
description: RNA 2-O ribose methyltransferase substrate binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00967
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00967_RNA_2-O_ribose_methyltransferase_substrate_binding


id: SM00975
description: Telomerase ribonucleoprotein complex - RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00975
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00975_Telomerase_ribonucleoprotein_complex_-_RNA_binding_domain


id: SM00976
description: Telomeric single stranded DNA binding POT1/CDC13
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00976
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00976_Telomeric_single_stranded_DNA_binding_POT1/CDC13


id: SM00978
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00978
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00978_Tim44_is_an_essential_component_of_the_machinery_that_mediates_the_translocation_of_nuclear-encoded_proteins_across_the_mitochondrial_inner_membrane_PUBMED:10430866._Tim44_is_thought_to_bind_phospholipids_of_the_mitochondrial_inner_membrane_both_by_...

description:
  Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane PUBMED:10430866. Tim44 is thought to bind phospholipids of the mitochondrial inner membrane both by ...


id: SM00981
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00981
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00981_The_THUMP_domain_is_named_after_after_thiouridine_synthases,_methylases_and_PSUSs_PUBMED:11295541._The_THUMP_domain_consists_of_about_110_amino_acid_residues._The_structure_of_ThiI_reveals_that_the_THUMP_has_a_fold_unlike_that_of_previously_...

description:
  The THUMP domain is named after after thiouridine synthases, methylases and PSUSs PUBMED:11295541. The THUMP domain consists of about 110 amino acid residues. The structure of ThiI reveals that the THUMP has a fold unlike that of previously ...


id: SM00983
description: Thiamin pyrophosphokinase, vitamin B1 binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00983
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00983_Thiamin_pyrophosphokinase,_vitamin_B1_binding_domain


id: SM00985
description: Ubiquitin-activating enzyme e1 C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00985
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00985_Ubiquitin-activating_enzyme_e1_C-terminal_domain


id: SM00987
description: UreE urease accessory protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00987
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00987_UreE_urease_accessory_protein,_C-terminal_domain


id: SM00990
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00990
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00990_This_entry_contains_proteins_with_the_VRR-NUC_domain._It_is_associated_with_members_of_the_PD-(D/E)XK_nuclease_superfamily,_which_include_the_type_III_restriction_modification_enzymes,_for_example_StyLTI.

description:
  This entry contains proteins with the VRR-NUC domain. It is associated with members of the PD-(D/E)XK nuclease superfamily, which include the type III restriction modification enzymes, for example StyLTI.


id: SM00991
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00991
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00991_A_conserved_domain_of_46_amino_acids,_called_WHEP-TRS_has_been_shown_PUBMED:1756734_to_exist_in_a_number_of_higher_eukaryote_aminoacyl-transfer_RNA_synthetases._This_domain_is_present_one_to_six_times_in_the_several_enzymes._There_are_three_copies_in_...

description:
  A conserved domain of 46 amino acids, called WHEP-TRS has been shown PUBMED:1756734 to exist in a number of higher eukaryote aminoacyl-transfer RNA synthetases. This domain is present one to six times in the several enzymes. There are three copies in ...


id: SM00997
description: S-adenosyl-L-homocysteine hydrolase, NAD binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM00997
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM00997_S-adenosyl-L-homocysteine_hydrolase,_NAD_binding_domain


id: SM01002
description: Alanine dehydrogenase/PNT, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01002
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01002_Alanine_dehydrogenase/PNT,_C-terminal_domain


id: SM01003
description: Alanine dehydrogenase/PNT, N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01003
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01003_Alanine_dehydrogenase/PNT,_N-terminal_domain


id: SM01006
description: Siderophore biosynthesis protein domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01006
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01006_Siderophore_biosynthesis_protein_domain


id: SM01007
description: Class II Aldolase and Adducin N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01007
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01007_Class_II_Aldolase_and_Adducin_N-terminal_domain


id: SM01010
description: 5-AMP-activated protein kinase beta subunit, interation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01010
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01010_5-AMP-activated_protein_kinase_beta_subunit,_interation_domain


id: SM01013
description: Anaphase promoting complex (APC) subunit 2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01013
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01013_Anaphase_promoting_complex_(APC)_subunit_2


id: SM01017
description: Arrestin (or S-antigen), C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01017
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01017_Arrestin_(or_S-antigen),_C-terminal_domain


id: SM01024
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01024
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01024_This_domain_is_found_at_the_N_terminal_of_the_mitochondrial_ATPase_BSC1._It_encodes_the_import_and_intramitochondrial_sorting_for_the_protein.

description:
  This domain is found at the N terminal of the mitochondrial ATPase BSC1. It encodes the import and intramitochondrial sorting for the protein.


id: SM01042
description: Di-sulfide bridge nucleocytoplasmic transport domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01042
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01042_Di-sulfide_bridge_nucleocytoplasmic_transport_domain


id: SM01050
description: Cactus-binding C-terminus of cactin protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01050
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01050_Cactus-binding_C-terminus_of_cactin_protein


id: SM01052
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01052
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01052_Cytoskeleton-associated_proteins_(CAPs)_are_involved_in_the_organisation_of_microtubules_and_transportation_of_vesicles_and_organelles_along_the_cytoskeletal_network._A_conserved_motif,_CAP-Gly,_has_been_identified_in_a_number_of_CAPs,_including_...

description:
  Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including ...


id: SM01060
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01060
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01060_Catalases_are_antioxidant_enzymes_that_catalyse_the_conversion_of_hydrogen_peroxide_to_water_and_molecular_oxygen,_serving_to_protect_cells_from_its_toxic_effects_PUBMED:11351128._Hydrogen_peroxide_is_produced_as_a_consequence_of_oxidative_cellular_...

description:
  Catalases are antioxidant enzymes that catalyse the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects PUBMED:11351128. Hydrogen peroxide is produced as a consequence of oxidative cellular ...


id: SM01072
description: Cell division protein 48 (CDC48) domain 2
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01072
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01072_Cell_division_protein_48_(CDC48)_domain_2


id: SM01073
description: Cell division protein 48 (CDC48) N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01073
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01073_Cell_division_protein_48_(CDC48)_N-terminal_domain


id: SM01077
description: Uncharacterized conserved protein CG6151-P
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01077
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01077_Uncharacterized_conserved_protein_CG6151-P


id: SM01083
description: N-terminal domain of CBF1 interacting co-repressor CIR
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01083
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01083_N-terminal_domain_of_CBF1_interacting_co-repressor_CIR


id: SM01084
description: Cyclin-dependent kinase regulatory subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01084
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01084_Cyclin-dependent_kinase_regulatory_subunit


id: SM01086
description: C-terminal, D2-small domain, of ClpB protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01086
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01086_C-terminal,_D2-small_domain,_of_ClpB_protein


id: SM01096
description: Carbamoyl-phosphate synthetase large chain, oligomerisation domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01096
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01096_Carbamoyl-phosphate_synthetase_large_chain,_oligomerisation_domain


id: SM01097
description: Carbamoyl-phosphate synthase small chain, CPSase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01097
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01097_Carbamoyl-phosphate_synthase_small_chain,_CPSase_domain


id: SM01098
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01098
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01098_This_is_the_C-terminal_conserved_region_of_the_pre-mRNA_3-end-processing_of_the_polyadenylation_factor_CPSF-73/CPSF-100_proteins._The_exact_function_of_this_domain_is_not_known.

description:
  This is the C-terminal conserved region of the pre-mRNA 3-end-processing of the polyadenylation factor CPSF-73/CPSF-100 proteins. The exact function of this domain is not known.


id: SM01104
description: Spt5 C-terminal nonapeptide repeat binding Spt4
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01104
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01104_Spt5_C-terminal_nonapeptide_repeat_binding_Spt4


id: SM01115
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01115
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01115_The_cwf21_family_is_involved_in_mRNA_splicing._It_has_been_isolated_as_a_subcomplex_of_the_splicosome_in_Schizosaccharomyces_pombe_(PUBMED:11884590)._The_function_of_the_cwf21_domain_is_to_bind_directly_to_the_spliceosomal_protein_Prp8._Mutations_in_...

description:
  The cwf21 family is involved in mRNA splicing. It has been isolated as a subcomplex of the splicosome in Schizosaccharomyces pombe (PUBMED:11884590). The function of the cwf21 domain is to bind directly to the spliceosomal protein Prp8. Mutations in ...


id: SM01117
description: Cytochrome b5-like Heme/Steroid binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01117
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01117_Cytochrome_b5-like_Heme/Steroid_binding_domain


id: SM01120
description: This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01120
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01120_This_domain_is_the_predicted_phosphatase_domain_of_the_dihydroxyacetone_kinase_family.


id: SM01124
description: Lariat debranching enzyme, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01124
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01124_Lariat_debranching_enzyme,_C-terminal_domain


id: SM01127
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01127
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01127_The_DDHD_domain_is_180_residues_long_and_contains_four_conserved_residues_that_may_form_a_metal_binding_site._The_domain_is_named_after_these_four_residues._This_pattern_of_conservation_of_metal_binding_residues_is_often_seen_in_phosphoesterase_...

description:
  The DDHD domain is 180 residues long and contains four conserved residues that may form a metal binding site. The domain is named after these four residues. This pattern of conservation of metal binding residues is often seen in phosphoesterase ...


id: SM01131
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01131
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01131_This_domain_is_often_found_adjacent_to_the_DHH_domain_PF01368_and_is_called_DHHA2_for_DHH_associated_domain._This_domain_is_diagnostic_of_DHH_subfamily_2_members_(PUBMED:9478130)._The_domain_is_about_120_residues_long_and_contains_a_conserved_DXK_...

description:
  This domain is often found adjacent to the DHH domain PF01368 and is called DHHA2 for DHH associated domain. This domain is diagnostic of DHH subfamily 2 members (PUBMED:9478130). The domain is about 120 residues long and contains a conserved DXK ...


id: SM01142
description: This C terminal domain is found in DOB1/SK12/helY-like DEAD box helicases [PUBMED:15112237].
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01142
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01142_This_C_terminal_domain_is_found_in_DOB1/SK12/helY-like_DEAD_box_helicases_[PUBMED:15112237].


id: SM01149
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01149
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01149_This_family_contains_a_number_of_hypothetical_proteins_of_about_450_residues_in_length._Their_function_is_unknown,_and_most_are_bacterial._However,_structurally_this_family_is_part_of_the_6_hairpin_glycosidase_superfamily,_suggesting_a_glycosyl_...

description:
  This family contains a number of hypothetical proteins of about 450 residues in length. Their function is unknown, and most are bacterial. However, structurally this family is part of the 6 hairpin glycosidase superfamily, suggesting a glycosyl ...


id: SM01155
description: Mitochondrial domain of unknown function (DUF1713)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01155
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01155_Mitochondrial_domain_of_unknown_function_(DUF1713)


id: SM01156
description: Eukaryotic domain of unknown function (DUF1716)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01156
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01156_Eukaryotic_domain_of_unknown_function_(DUF1716)


id: SM01158
description: This is a eukaryotic domain of unknown function.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01158
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01158_This_is_a_eukaryotic_domain_of_unknown_function.


id: SM01159
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01159
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01159_This_domain_is_found_on_the_epsilon_catalytic_subunit_of_DNA_polymerase._It_is_found_C_terminal_to_POLBc_(SM00486).

description:
  This domain is found on the epsilon catalytic subunit of DNA polymerase. It is found C terminal to POLBc (SM00486).


id: SM01160
description: Eukaryotic integral membrane protein (DUF1751)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01160
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01160_Eukaryotic_integral_membrane_protein_(DUF1751)


id: SM01161
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01161
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01161_Eukaryotic_domain_of_unknown_function._This_domain_is_found_to_the_N-terminus_of_the_nucleic_acid_binding_domain.

description:
  Eukaryotic domain of unknown function. This domain is found to the N-terminus of the nucleic acid binding domain.


id: SM01162
description: This domain is always found adjacent to SMR (SM00463).
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01162
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01162_This_domain_is_always_found_adjacent_to_SMR_(SM00463).


id: SM01163
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01163
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01163_This_region_is_found_in_argonaute_[PUBMED:16216572]_proteins_and_often_co-occurs_with_BAG_(SM00264)_and_Piwi_(SM00950).

description:
  This region is found in argonaute [PUBMED:16216572] proteins and often co-occurs with BAG (SM00264) and Piwi (SM00950).


id: SM01166
description: This set of domains is found in various eukaryotic proteins. Function is unknown.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01166
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01166_This_set_of_domains_is_found_in_various_eukaryotic_proteins._Function_is_unknown.


id: SM01167
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01167
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01167_This_domain_is_predominantly_found_in_the_structural_protein_coronin,_and_is_duplicated_in_some_sequences._It_has_no_known_function_[PUBMED:16172398].

description:
  This domain is predominantly found in the structural protein coronin, and is duplicated in some sequences. It has no known function [PUBMED:16172398].


id: SM01173
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01173
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01173_This_family_is_found_at_the_very_C-terminus_of_proteins_that_carry_a_G-patch_domain_SM00443._The_domain_is_short_and_cysteine-rich_.

description:
  This family is found at the very C-terminus of proteins that carry a G-patch domain SM00443. The domain is short and cysteine-rich .


id: SM01176
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01176
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01176_This_domain_is_found_at_the_C-terminus_of_chromodomain-helicase-DNA-binding_proteins._The_exact_function_of_the_domain_is_undetermined.

description:
  This domain is found at the C-terminus of chromodomain-helicase-DNA-binding proteins. The exact function of the domain is undetermined.


id: SM01177
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01177
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01177_This_short_domain_is_found_in_fungi,_plants_and_animals,_and_the_proteins_appear_to_be_necessary_for_chromosome_segregation_during_meiosis.

description:
  This short domain is found in fungi, plants and animals, and the proteins appear to be necessary for chromosome segregation during meiosis.


id: SM01178
description: This short domain is found at the C-terminus of many helicase proteins.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01178
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01178_This_short_domain_is_found_at_the_C-terminus_of_many_helicase_proteins.


id: SM01180
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01180
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01180_DWNN_is_a_ubiquitin_like_domain_found_at_the_N-terminus_of_the_RBBP6_family_of_splicing-associated_proteins_PUBMED:16396680._The_DWNN_domain_is_independently_expressed_in_higher_vertebrates_so_it_may_function_as_a_novel_ubiquitin-like_modifier_of_...

description:
  DWNN is a ubiquitin like domain found at the N-terminus of the RBBP6 family of splicing-associated proteins PUBMED:16396680. The DWNN domain is independently expressed in higher vertebrates so it may function as a novel ubiquitin-like modifier of ...


id: SM01181
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01181
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01181_E1_and_E2_enzymes_play_a_central_role_in_ubiquitin_and_ubiquitin-like_protein_transfer_cascades._This_is_an_E2_binding_domain_that_is_found_on_NEDD8_activating_E1_enzyme._The_domain_resembles_ubiquitin,_and_recruits_the_catalytic_core_of_the_E2_...

description:
  E1 and E2 enzymes play a central role in ubiquitin and ubiquitin-like protein transfer cascades. This is an E2 binding domain that is found on NEDD8 activating E1 enzyme. The domain resembles ubiquitin, and recruits the catalytic core of the E2 ...


id: SM01182
description: Eukaryotic elongation factor 1 beta central acidic region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01182
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01182_Eukaryotic_elongation_factor_1_beta_central_acidic_region


id: SM01183
description: Elongation factor 1 gamma, conserved domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01183
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01183_Elongation_factor_1_gamma,_conserved_domain


id: SM01194
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01194
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01194_The_release_factor_eRF1_terminates_protein_biosynthesis_by_recognising_stop_codons_at_the_A_site_of_the_ribosome_and_stimulating_peptidyl-tRNA_bond_hydrolysis_at_the_peptidyl_transferase_centre._The_crystal_structure_of_human_eRF1_is_known_...

description:
  The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of human eRF1 is known ...


id: SM01199
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01199
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01199_The_FDF_domain,_so_called_because_of_the_conserved_FDF_at_its_N_termini,_is_an_entirely_alpha-helical_domain_with_multiple_exposed_hydrophilic_loops._It_is_found_at_the_C_terminus_of_Scd6p-like_SM_domains._It_is_also_found_with_other_divergent_Sm_...

description:
  The FDF domain, so called because of the conserved FDF at its N termini, is an entirely alpha-helical domain with multiple exposed hydrophilic loops. It is found at the C terminus of Scd6p-like SM domains. It is also found with other divergent Sm ...


id: SM01209
description: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01209
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01209_Phosphoribosylglycinamide_synthetase,_ATP-grasp_(A)_domain


id: SM01210
description: Phosphoribosylglycinamide synthetase, C domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01210
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01210_Phosphoribosylglycinamide_synthetase,_C_domain


id: SM01211
description: CobB/CobQ-like glutamine amidotransferase domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01211
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01211_CobB/CobQ-like_glutamine_amidotransferase_domain


id: SM01213
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01213
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01213_This_presumed_domain_is_found_at_the_N-terminus_of_the_S._cerevisiae_Flo11_protein._Flo11_is_required_for_diploid_pseudohyphal_formation_and_haploid_invasive_growth._It_belongs_to_a_family_of_proteins_involved_in_invasive_growth,_cell-cell_adhesion,_...

description:
  This presumed domain is found at the N-terminus of the S. cerevisiae Flo11 protein. Flo11 is required for diploid pseudohyphal formation and haploid invasive growth. It belongs to a family of proteins involved in invasive growth, cell-cell adhesion, ...


id: SM01214
description: RNA pol II promoter Fmp27 protein domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01214
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01214_RNA_pol_II_promoter_Fmp27_protein_domain


id: SM01215
description: RNA pol II promoter Fmp27 protein domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01215
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01215_RNA_pol_II_promoter_Fmp27_protein_domain


id: SM01216
description: RNA pol II promoter Fmp27 protein domain Provide feedback
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01216
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01216_RNA_pol_II_promoter_Fmp27_protein_domain_Provide_feedback


id: SM01218
description: C-terminal duplication domain of Friend of PRMT1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01218
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01218_C-terminal_duplication_domain_of_Friend_of_PRMT1


id: SM01238
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01238
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01238_This_domain_is_found_in_fungal_proteins_and_contains_a_conserved_IGR_motif._Its_function_is_unknown.

description:
  This domain is found in fungal proteins and contains a conserved IGR motif. Its function is unknown.


id: SM01252
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01252
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01252_Conserved_DNA-binding_domain_that_is_found_in_a_wide_range_of_proteins_of_large_bacterial_and_eukaryotic_DNA_viruses.

description:
  Conserved DNA-binding domain that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses.


id: SM01253
description: Domain of Kin17 curved DNA-binding protein
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01253
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01253_Domain_of_Kin17_curved_DNA-binding_protein


id: SM01272
description: This domain is found associated with Lsm domain PMID:16115810.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01272
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01272_This_domain_is_found_associated_with_Lsm_domain_PMID:16115810.


id: SM01281
description: Transcription mediator complex subunit Med12
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01281
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01281_Transcription_mediator_complex_subunit_Med12


id: SM01285
description: FACT complex subunit SPT16 N-terminal lobe domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01285
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01285_FACT_complex_subunit_SPT16_N-terminal_lobe_domain


id: SM01291
description: COMPASS (Complex proteins associated with Set1p) component N
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01291
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01291_COMPASS_(Complex_proteins_associated_with_Set1p)_component_N


id: SM01296
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01296
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01296_This_family_features_sequences_that_are_similar_to_a_region_of_hypothetical_yeast_gene_product_N2227._This_is_thought_to_be_expressed_during_meiosis_and_may_be_involved_in_the_defence_response_to_stressful_conditions_PMID:8771715.

description:
  This family features sequences that are similar to a region of hypothetical yeast gene product N2227. This is thought to be expressed during meiosis and may be involved in the defence response to stressful conditions PMID:8771715.


id: SM01303
description: Rapamycin-insensitive companion of mTOR RasGEF_N domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01303
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01303_Rapamycin-insensitive_companion_of_mTOR_RasGEF_N_domain


id: SM01307
description: Rapamycin-insensitive companion of mTOR, middle domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01307
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01307_Rapamycin-insensitive_companion_of_mTOR,_middle_domain


id: SM01308
description: Rapamycin-insensitive companion of mTOR, N-term
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01308
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01308_Rapamycin-insensitive_companion_of_mTOR,_N-term


id: SM01310
description: Rapamycin-insensitive companion of mTOR, domain 5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01310
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01310_Rapamycin-insensitive_companion_of_mTOR,_domain_5


id: SM01313
description: Exocyst complex component SEC3 N-terminal PIP2 binding PH
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01313
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01313_Exocyst_complex_component_SEC3_N-terminal_PIP2_binding_PH


id: SM01314
description: Snf2-ATP coupling, chromatin remodelling complex
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01314
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01314_Snf2-ATP_coupling,_chromatin_remodelling_complex


id: SM01327
description: Activator of mitotic machinery Cdc14 phosphatase activation C-term
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01327
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01327_Activator_of_mitotic_machinery_Cdc14_phosphatase_activation_C-term


id: SM01329
description: Isocitrate/isopropylmalate dehydrogenase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01329
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01329_Isocitrate/isopropylmalate_dehydrogenase


id: SM01332
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01332
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01332_Cyclins_are_a_family_of_proteins_that_control_the_progression_of_cells_through_the_cell_cycle_by_activating_cyclin-dependent_kinase_(Cdk)_enzymes.

description:
  Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.


id: SM01336
description: Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01336
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01336_Poly(ADP-ribose)_polymerase_and_DNA-Ligase_Zn-finger_region


id: SM01337
description: Anaphase-promoting complex, subunit 10 (APC10)
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01337
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01337_Anaphase-promoting_complex,_subunit_10_(APC10)


id: SM01340
description: DNA mismatch repair protein, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01340
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01340_DNA_mismatch_repair_protein,_C-terminal_domain


id: SM01342
description: Telomere-length maintenance and DNA damage repair
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01342
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01342_Telomere-length_maintenance_and_DNA_damage_repair


id: SM01343
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01343
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01343_The_FATC_domain_is_named_after_FRAP,_ATM,_TRRAP_C-terminal_(PMID:10782091)._The_solution_structure_of_the_FATC_domain_suggests_it_plays_a_role_in_redox-dependent_structural_and_cellular_stability_(PMID:15772072).

description:
  The FATC domain is named after FRAP, ATM, TRRAP C-terminal (PMID:10782091). The solution structure of the FATC domain suggests it plays a role in redox-dependent structural and cellular stability (PMID:15772072).


id: SM01349
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01349
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01349_XMAP215/Dis1_proteins,_such_as_Alp14_and_XMAP215,_increase_microtubules_dynamic_polymerization_rates_by_recruiting_soluble_αβ-tubulin_via_their_conserved_TOG_domains_to_polymerizing_microtubule_plus_ends.

description:
  XMAP215/Dis1 proteins, such as Alp14 and XMAP215, increase microtubules dynamic polymerization rates by recruiting soluble αβ-tubulin via their conserved TOG domains to polymerizing microtubule plus ends.


id: SM01350
description: 6-phosphogluconate dehydrogenase, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01350
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01350_6-phosphogluconate_dehydrogenase,_C-terminal_domain


id: SM01371
description: Transcription factor IIA, alpha/beta subunit
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01371
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01371_Transcription_factor_IIA,_alpha/beta_subunit


id: SM01376
description: Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01376
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01376_Eukaryotic_elongation_factor_5A_hypusine,_DNA-binding_OB_fold


id: SM01377
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01377
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01377_Bovine_L40_has_been_identified_as_a_secondary_RNA_binding_protein_(PMID:3129699)._L40_is_fused_to_a_ubiquitin_protein_(PMID:7488009).

description:
  Bovine L40 has been identified as a secondary RNA binding protein (PMID:3129699). L40 is fused to a ubiquitin protein (PMID:7488009).


id: SM01378
description: Reactive mitochondrial oxygen species modulator 1
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01378
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01378_Reactive_mitochondrial_oxygen_species_modulator_1


id: SM01382
description: Ribosomal Proteins L2, C-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01382
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01382_Ribosomal_Proteins_L2,_C-terminal_domain


id: SM01383
description: Ribosomal Proteins L2, RNA binding domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01383
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01383_Ribosomal_Proteins_L2,_RNA_binding_domain


id: SM01385
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01385
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01385_This_family_contains_the_breast_cancer_tumour_suppressor_BRCA2-interacting_protein_DSS1_and_its_homologue_SEM1,_both_of_which_are_short_acidic_proteins._DSS1_has_been_shown_to_be_a_conserved_component_of_the_Rae1_mediated_mRNA_export_pathway_in_...

description:
  This family contains the breast cancer tumour suppressor BRCA2-interacting protein DSS1 and its homologue SEM1, both of which are short acidic proteins. DSS1 has been shown to be a conserved component of the Rae1 mediated mRNA export pathway in ...


id: SM01390
description: Ribosomal protein S4/S9 N-terminal domain
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01390
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01390_Ribosomal_protein_S4/S9_N-terminal_domain


id: SM01393
description: This family includes ribosomal protein L32 from eukaryotes and archaebacteria.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01393
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01393_This_family_includes_ribosomal_protein_L32_from_eukaryotes_and_archaebacteria.


id: SM01395
description: Transcription factor TFIIH complex subunit Tfb5
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01395
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01395_Transcription_factor_TFIIH_complex_subunit_Tfb5


id: SM01400
description: N-terminal domain of ribose phosphate pyrophosphokinase
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01400
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01400_N-terminal_domain_of_ribose_phosphate_pyrophosphokinase


id: SM01406
description: Family of proteins with a conserved region found in PAPA-1, a PAP-1 binding protein.
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01406
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01406_Family_of_proteins_with_a_conserved_region_found_in_PAPA-1,_a_PAP-1_binding_protein.


id: SM01408
description: Inhibitor of growth proteins N-terminal histone-binding
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01408
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01408_Inhibitor_of_growth_proteins_N-terminal_histone-binding


id: SM01477
description: DDE transposase retroviral integrase sub-family
memo: http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=SM01477
name:
  Protein Domains (SMART).STRING_v12.0_284812_STRINGid_SM01477_DDE_transposase_retroviral_integrase_sub-family


id: SPO-110313
description: Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
memo: https://reactome.org/content/detail/SPO-110313
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-110313_Translesion_synthesis_by_Y_family_DNA_polymerases_bypasses_lesions_on_DNA_template


id: SPO-110314
description: Recognition of DNA damage by PCNA-containing replication complex
memo: https://reactome.org/content/detail/SPO-110314
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-110314_Recognition_of_DNA_damage_by_PCNA-containing_replication_complex


id: SPO-110373
description: Resolution of AP sites via the multiple-nucleotide patch replacement pathway
memo: https://reactome.org/content/detail/SPO-110373
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-110373_Resolution_of_AP_sites_via_the_multiple-nucleotide_patch_replacement_pathway


id: SPO-111457
description: Release of apoptotic factors from the mitochondria
memo: https://reactome.org/content/detail/SPO-111457
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-111457_Release_of_apoptotic_factors_from_the_mitochondria


id: SPO-112314
description: Neurotransmitter receptors and postsynaptic signal transmission
memo: https://reactome.org/content/detail/SPO-112314
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-112314_Neurotransmitter_receptors_and_postsynaptic_signal_transmission


id: SPO-113501
description: Inhibition of replication initiation of damaged DNA by RB1/E2F1
memo: https://reactome.org/content/detail/SPO-113501
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-113501_Inhibition_of_replication_initiation_of_damaged_DNA_by_RB1/E2F1


id: SPO-113510
description: E2F mediated regulation of DNA replication
memo: https://reactome.org/content/detail/SPO-113510
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-113510_E2F_mediated_regulation_of_DNA_replication


id: SPO-1168372
description: Downstream signaling events of B Cell Receptor (BCR)
memo: https://reactome.org/content/detail/SPO-1168372
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1168372_Downstream_signaling_events_of_B_Cell_Receptor_(BCR)


id: SPO-1236978
description: Cross-presentation of soluble exogenous antigens (endosomes)
memo: https://reactome.org/content/detail/SPO-1236978
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1236978_Cross-presentation_of_soluble_exogenous_antigens_(endosomes)


id: SPO-1362409
description: Mitochondrial iron-sulfur cluster biogenesis
memo: https://reactome.org/content/detail/SPO-1362409
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1362409_Mitochondrial_iron-sulfur_cluster_biogenesis


id: SPO-141405
memo: https://reactome.org/content/detail/SPO-141405
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-141405_Inhibition_of_the_proteolytic_activity_of_APC/C_required_for_the_onset_of_anaphase_by_mitotic_spindle_checkpoint_components

description:
  Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components


id: SPO-141430
description: Inactivation of APC/C via direct inhibition of the APC/C complex
memo: https://reactome.org/content/detail/SPO-141430
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-141430_Inactivation_of_APC/C_via_direct_inhibition_of_the_APC/C_complex


id: SPO-1428517
description: The citric acid (TCA) cycle and respiratory electron transport
memo: https://reactome.org/content/detail/SPO-1428517
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1428517_The_citric_acid_(TCA)_cycle_and_respiratory_electron_transport


id: SPO-1474151
description: Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
memo: https://reactome.org/content/detail/SPO-1474151
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1474151_Tetrahydrobiopterin_(BH4)_synthesis,_recycling,_salvage_and_regulation


id: SPO-156827
description: L13a-mediated translational silencing of Ceruloplasmin expression
memo: https://reactome.org/content/detail/SPO-156827
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-156827_L13a-mediated_translational_silencing_of_Ceruloplasmin_expression


id: SPO-159227
description: Transport of the SLBP independent Mature mRNA
memo: https://reactome.org/content/detail/SPO-159227
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-159227_Transport_of_the_SLBP_independent_Mature_mRNA


id: SPO-159231
description: Transport of Mature mRNA Derived from an Intronless Transcript
memo: https://reactome.org/content/detail/SPO-159231
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-159231_Transport_of_Mature_mRNA_Derived_from_an_Intronless_Transcript


id: SPO-159234
description: Transport of Mature mRNAs Derived from Intronless Transcripts
memo: https://reactome.org/content/detail/SPO-159234
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-159234_Transport_of_Mature_mRNAs_Derived_from_Intronless_Transcripts


id: SPO-159236
description: Transport of Mature mRNA derived from an Intron-Containing Transcript
memo: https://reactome.org/content/detail/SPO-159236
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-159236_Transport_of_Mature_mRNA_derived_from_an_Intron-Containing_Transcript


id: SPO-162658
description: Golgi Cisternae Pericentriolar Stack Reorganization
memo: https://reactome.org/content/detail/SPO-162658
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-162658_Golgi_Cisternae_Pericentriolar_Stack_Reorganization


id: SPO-162710
description: Synthesis of glycosylphosphatidylinositol (GPI)
memo: https://reactome.org/content/detail/SPO-162710
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-162710_Synthesis_of_glycosylphosphatidylinositol_(GPI)


id: SPO-163125
description: Post-translational modification: synthesis of GPI-anchored proteins
memo: https://reactome.org/content/detail/SPO-163125
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-163125_Post-translational_modification:_synthesis_of_GPI-anchored_proteins


id: SPO-163200
memo: https://reactome.org/content/detail/SPO-163200
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-163200_Respiratory_electron_transport,_ATP_synthesis_by_chemiosmotic_coupling,_and_heat_production_by_uncoupling_proteins.

description:
  Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.


id: SPO-163359
description: Glucagon signaling in metabolic regulation
memo: https://reactome.org/content/detail/SPO-163359
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-163359_Glucagon_signaling_in_metabolic_regulation


id: SPO-163680
description: AMPK inhibits chREBP transcriptional activation activity
memo: https://reactome.org/content/detail/SPO-163680
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-163680_AMPK_inhibits_chREBP_transcriptional_activation_activity


id: SPO-163765
description: ChREBP activates metabolic gene expression
memo: https://reactome.org/content/detail/SPO-163765
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-163765_ChREBP_activates_metabolic_gene_expression


id: SPO-163841
description: Gamma carboxylation, hypusine formation and arylsulfatase activation
memo: https://reactome.org/content/detail/SPO-163841
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-163841_Gamma_carboxylation,_hypusine_formation_and_arylsulfatase_activation


id: SPO-165181
description: Inhibition of TSC complex formation by PKB
memo: https://reactome.org/content/detail/SPO-165181
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-165181_Inhibition_of_TSC_complex_formation_by_PKB


id: SPO-1660516
description: Synthesis of PIPs at the early endosome membrane
memo: https://reactome.org/content/detail/SPO-1660516
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1660516_Synthesis_of_PIPs_at_the_early_endosome_membrane


id: SPO-1660517
description: Synthesis of PIPs at the late endosome membrane
memo: https://reactome.org/content/detail/SPO-1660517
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1660517_Synthesis_of_PIPs_at_the_late_endosome_membrane


id: SPO-166058
description: MyD88:MAL(TIRAP) cascade initiated on plasma membrane
memo: https://reactome.org/content/detail/SPO-166058
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-166058_MyD88:MAL(TIRAP)_cascade_initiated_on_plasma_membrane


id: SPO-168643
description: Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
memo: https://reactome.org/content/detail/SPO-168643
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-168643_Nucleotide-binding_domain,_leucine_rich_repeat_containing_receptor_(NLR)_signaling_pathways


id: SPO-170822
description: Regulation of Glucokinase by Glucokinase Regulatory Protein
memo: https://reactome.org/content/detail/SPO-170822
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-170822_Regulation_of_Glucokinase_by_Glucokinase_Regulatory_Protein


id: SPO-174143
description: APC/C-mediated degradation of cell cycle proteins
memo: https://reactome.org/content/detail/SPO-174143
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-174143_APC/C-mediated_degradation_of_cell_cycle_proteins


id: SPO-174824
description: Plasma lipoprotein assembly, remodeling, and clearance
memo: https://reactome.org/content/detail/SPO-174824
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-174824_Plasma_lipoprotein_assembly,_remodeling,_and_clearance


id: SPO-176187
description: Activation of ATR in response to replication stress
memo: https://reactome.org/content/detail/SPO-176187
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-176187_Activation_of_ATR_in_response_to_replication_stress


id: SPO-176407
description: Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
memo: https://reactome.org/content/detail/SPO-176407
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-176407_Conversion_from_APC/C:Cdc20_to_APC/C:Cdh1_in_late_anaphase


id: SPO-176408
description: Regulation of APC/C activators between G1/S and early anaphase
memo: https://reactome.org/content/detail/SPO-176408
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-176408_Regulation_of_APC/C_activators_between_G1/S_and_early_anaphase


id: SPO-176409
description: APC/C:Cdc20 mediated degradation of mitotic proteins
memo: https://reactome.org/content/detail/SPO-176409
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-176409_APC/C:Cdc20_mediated_degradation_of_mitotic_proteins


id: SPO-176814
description: Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
memo: https://reactome.org/content/detail/SPO-176814
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-176814_Activation_of_APC/C_and_APC/C:Cdc20_mediated_degradation_of_mitotic_proteins


id: SPO-179419
memo: https://reactome.org/content/detail/SPO-179419
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-179419_APC:Cdc20_mediated_degradation_of_cell_cycle_proteins_prior_to_satisfation_of_the_cell_cycle_checkpoint

description:
  APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint


id: SPO-1799339
description: SRP-dependent cotranslational protein targeting to membrane
memo: https://reactome.org/content/detail/SPO-1799339
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1799339_SRP-dependent_cotranslational_protein_targeting_to_membrane


id: SPO-1855167
description: Synthesis of pyrophosphates in the cytosol
memo: https://reactome.org/content/detail/SPO-1855167
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1855167_Synthesis_of_pyrophosphates_in_the_cytosol


id: SPO-1855183
description: Synthesis of IP2, IP, and Ins in the cytosol
memo: https://reactome.org/content/detail/SPO-1855183
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-1855183_Synthesis_of_IP2,_IP,_and_Ins_in_the_cytosol


id: SPO-193368
description: Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
memo: https://reactome.org/content/detail/SPO-193368
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-193368_Synthesis_of_bile_acids_and_bile_salts_via_7alpha-hydroxycholesterol


id: SPO-193775
description: Synthesis of bile acids and bile salts via 24-hydroxycholesterol
memo: https://reactome.org/content/detail/SPO-193775
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-193775_Synthesis_of_bile_acids_and_bile_salts_via_24-hydroxycholesterol


id: SPO-193807
description: Synthesis of bile acids and bile salts via 27-hydroxycholesterol
memo: https://reactome.org/content/detail/SPO-193807
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-193807_Synthesis_of_bile_acids_and_bile_salts_via_27-hydroxycholesterol


id: SPO-196849
description: Metabolism of water-soluble vitamins and cofactors
memo: https://reactome.org/content/detail/SPO-196849
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-196849_Metabolism_of_water-soluble_vitamins_and_cofactors


id: SPO-198725
description: Nuclear Events (kinase and transcription factor activation)
memo: https://reactome.org/content/detail/SPO-198725
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-198725_Nuclear_Events_(kinase_and_transcription_factor_activation)


id: SPO-199418
description: Negative regulation of the PI3K/AKT network
memo: https://reactome.org/content/detail/SPO-199418
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-199418_Negative_regulation_of_the_PI3K/AKT_network


id: SPO-202131
description: Metabolism of nitric oxide: NOS3 activation and regulation
memo: https://reactome.org/content/detail/SPO-202131
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-202131_Metabolism_of_nitric_oxide:_NOS3_activation_and_regulation


id: SPO-2029480
description: Fcgamma receptor (FCGR) dependent phagocytosis
memo: https://reactome.org/content/detail/SPO-2029480
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2029480_Fcgamma_receptor_(FCGR)_dependent_phagocytosis


id: SPO-2029482
description: Regulation of actin dynamics for phagocytic cup formation
memo: https://reactome.org/content/detail/SPO-2029482
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2029482_Regulation_of_actin_dynamics_for_phagocytic_cup_formation


id: SPO-204174
description: Regulation of pyruvate dehydrogenase (PDH) complex
memo: https://reactome.org/content/detail/SPO-204174
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-204174_Regulation_of_pyruvate_dehydrogenase_(PDH)_complex


id: SPO-2142691
description: Synthesis of Leukotrienes (LT) and Eoxins (EX)
memo: https://reactome.org/content/detail/SPO-2142691
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2142691_Synthesis_of_Leukotrienes_(LT)_and_Eoxins_(EX)


id: SPO-2162123
description: Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
memo: https://reactome.org/content/detail/SPO-2162123
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2162123_Synthesis_of_Prostaglandins_(PG)_and_Thromboxanes_(TX)


id: SPO-2404192
description: Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
memo: https://reactome.org/content/detail/SPO-2404192
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2404192_Signaling_by_Type_1_Insulin-like_Growth_Factor_1_Receptor_(IGF1R)


id: SPO-2514859
description: Inactivation, recovery and regulation of the phototransduction cascade
memo: https://reactome.org/content/detail/SPO-2514859
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2514859_Inactivation,_recovery_and_regulation_of_the_phototransduction_cascade


id: SPO-2559582
description: Senescence-Associated Secretory Phenotype (SASP)
memo: https://reactome.org/content/detail/SPO-2559582
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2559582_Senescence-Associated_Secretory_Phenotype_(SASP)


id: SPO-2559586
description: DNA Damage/Telomere Stress Induced Senescence
memo: https://reactome.org/content/detail/SPO-2559586
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2559586_DNA_Damage/Telomere_Stress_Induced_Senescence


id: SPO-2995383
description: Initiation of Nuclear Envelope (NE) Reformation
memo: https://reactome.org/content/detail/SPO-2995383
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-2995383_Initiation_of_Nuclear_Envelope_(NE)_Reformation


id: SPO-3065678
description: SUMO is transferred from E1 to E2 (UBE2I, UBC9)
memo: https://reactome.org/content/detail/SPO-3065678
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-3065678_SUMO_is_transferred_from_E1_to_E2_(UBE2I,_UBC9)


id: SPO-3108214
description: SUMOylation of DNA damage response and repair proteins
memo: https://reactome.org/content/detail/SPO-3108214
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-3108214_SUMOylation_of_DNA_damage_response_and_repair_proteins


id: SPO-3108232
description: SUMO E3 ligases SUMOylate target proteins
memo: https://reactome.org/content/detail/SPO-3108232
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-3108232_SUMO_E3_ligases_SUMOylate_target_proteins


id: SPO-3299685
description: Detoxification of Reactive Oxygen Species
memo: https://reactome.org/content/detail/SPO-3299685
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-3299685_Detoxification_of_Reactive_Oxygen_Species


id: SPO-3371453
description: Regulation of HSF1-mediated heat shock response
memo: https://reactome.org/content/detail/SPO-3371453
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-3371453_Regulation_of_HSF1-mediated_heat_shock_response


id: SPO-3371497
description: HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
memo: https://reactome.org/content/detail/SPO-3371497
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-3371497_HSP90_chaperone_cycle_for_steroid_hormone_receptors_(SHR)_in_the_presence_of_ligand


id: SPO-350562
description: Regulation of ornithine decarboxylase (ODC)
memo: https://reactome.org/content/detail/SPO-350562
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-350562_Regulation_of_ornithine_decarboxylase_(ODC)


id: SPO-379401
description: Dopamine clearance from the synaptic cleft
memo: https://reactome.org/content/detail/SPO-379401
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-379401_Dopamine_clearance_from_the_synaptic_cleft


id: SPO-380972
description: Energy dependent regulation of mTOR by LKB1-AMPK
memo: https://reactome.org/content/detail/SPO-380972
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-380972_Energy_dependent_regulation_of_mTOR_by_LKB1-AMPK


id: SPO-381771
description: Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
memo: https://reactome.org/content/detail/SPO-381771
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-381771_Synthesis,_secretion,_and_inactivation_of_Glucagon-like_Peptide-1_(GLP-1)


id: SPO-389661
description: Glyoxylate metabolism and glycine degradation
memo: https://reactome.org/content/detail/SPO-389661
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-389661_Glyoxylate_metabolism_and_glycine_degradation


id: SPO-390471
description: Association of TriC/CCT with target proteins during biosynthesis
memo: https://reactome.org/content/detail/SPO-390471
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-390471_Association_of_TriC/CCT_with_target_proteins_during_biosynthesis


id: SPO-400451
description: Free fatty acids regulate insulin secretion
memo: https://reactome.org/content/detail/SPO-400451
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-400451_Free_fatty_acids_regulate_insulin_secretion


id: SPO-400508
description: Incretin synthesis, secretion, and inactivation
memo: https://reactome.org/content/detail/SPO-400508
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-400508_Incretin_synthesis,_secretion,_and_inactivation


id: SPO-425366
description: Transport of bile salts and organic acids, metal ions and amine compounds
memo: https://reactome.org/content/detail/SPO-425366
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-425366_Transport_of_bile_salts_and_organic_acids,_metal_ions_and_amine_compounds


id: SPO-425393
description: Transport of inorganic cations/anions and amino acids/oligopeptides
memo: https://reactome.org/content/detail/SPO-425393
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-425393_Transport_of_inorganic_cations/anions_and_amino_acids/oligopeptides


id: SPO-425397
description: Transport of vitamins, nucleosides, and related molecules
memo: https://reactome.org/content/detail/SPO-425397
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-425397_Transport_of_vitamins,_nucleosides,_and_related_molecules


id: SPO-432040
description: Vasopressin regulates renal water homeostasis via Aquaporins
memo: https://reactome.org/content/detail/SPO-432040
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-432040_Vasopressin_regulates_renal_water_homeostasis_via_Aquaporins


id: SPO-434313
description: Intracellular metabolism of fatty acids regulates insulin secretion
memo: https://reactome.org/content/detail/SPO-434313
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-434313_Intracellular_metabolism_of_fatty_acids_regulates_insulin_secretion


id: SPO-434316
description: Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
memo: https://reactome.org/content/detail/SPO-434316
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-434316_Fatty_Acids_bound_to_GPR40_(FFAR1)_regulate_insulin_secretion


id: SPO-435368
description: Zinc efflux and compartmentalization by the SLC30 family
memo: https://reactome.org/content/detail/SPO-435368
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-435368_Zinc_efflux_and_compartmentalization_by_the_SLC30_family


id: SPO-442720
description: CREB1 phosphorylation through the activation of Adenylate Cyclase
memo: https://reactome.org/content/detail/SPO-442720
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-442720_CREB1_phosphorylation_through_the_activation_of_Adenylate_Cyclase


id: SPO-442755
description: Activation of NMDA receptors and postsynaptic events
memo: https://reactome.org/content/detail/SPO-442755
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-442755_Activation_of_NMDA_receptors_and_postsynaptic_events


id: SPO-446193
memo: https://reactome.org/content/detail/SPO-446193
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-446193_Biosynthesis_of_the_N-glycan_precursor_(dolichol_lipid-linked_oligosaccharide,_LLO)_and_transfer_to_a_nascent_protein

description:
  Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein


id: SPO-446219
description: Synthesis of substrates in N-glycan biosythesis
memo: https://reactome.org/content/detail/SPO-446219
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-446219_Synthesis_of_substrates_in_N-glycan_biosythesis


id: SPO-450282
description: MAPK targets/ Nuclear events mediated by MAP kinases
memo: https://reactome.org/content/detail/SPO-450282
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-450282_MAPK_targets/_Nuclear_events_mediated_by_MAP_kinases


id: SPO-450302
description: Activated TAK1 mediates p38 MAPK activation
memo: https://reactome.org/content/detail/SPO-450302
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-450302_Activated_TAK1_mediates_p38_MAPK_activation


id: SPO-450341
description: Activation of the AP-1 family of transcription factors
memo: https://reactome.org/content/detail/SPO-450341
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-450341_Activation_of_the_AP-1_family_of_transcription_factors


id: SPO-450531
description: Regulation of mRNA stability by proteins that bind AU-rich elements
memo: https://reactome.org/content/detail/SPO-450531
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-450531_Regulation_of_mRNA_stability_by_proteins_that_bind_AU-rich_elements


id: SPO-4551638
description: SUMOylation of chromatin organization proteins
memo: https://reactome.org/content/detail/SPO-4551638
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-4551638_SUMOylation_of_chromatin_organization_proteins


id: SPO-499943
description: Interconversion of nucleotide di- and triphosphates
memo: https://reactome.org/content/detail/SPO-499943
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-499943_Interconversion_of_nucleotide_di-_and_triphosphates


id: SPO-5223345
description: Miscellaneous transport and binding events
memo: https://reactome.org/content/detail/SPO-5223345
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5223345_Miscellaneous_transport_and_binding_events


id: SPO-532668
description: N-glycan trimming in the ER and Calnexin/Calreticulin cycle
memo: https://reactome.org/content/detail/SPO-532668
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-532668_N-glycan_trimming_in_the_ER_and_Calnexin/Calreticulin_cycle


id: SPO-5358565
description: Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
memo: https://reactome.org/content/detail/SPO-5358565
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5358565_Mismatch_repair_(MMR)_directed_by_MSH2:MSH6_(MutSalpha)


id: SPO-5358606
description: Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
memo: https://reactome.org/content/detail/SPO-5358606
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5358606_Mismatch_repair_(MMR)_directed_by_MSH2:MSH3_(MutSbeta)


id: SPO-5620912
description: Anchoring of the basal body to the plasma membrane
memo: https://reactome.org/content/detail/SPO-5620912
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5620912_Anchoring_of_the_basal_body_to_the_plasma_membrane


id: SPO-5620920
description: Cargo trafficking to the periciliary membrane
memo: https://reactome.org/content/detail/SPO-5620920
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5620920_Cargo_trafficking_to_the_periciliary_membrane


id: SPO-5633008
description: TP53 Regulates Transcription of Cell Death Genes
memo: https://reactome.org/content/detail/SPO-5633008
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5633008_TP53_Regulates_Transcription_of_Cell_Death_Genes


id: SPO-5651801
description: PCNA-Dependent Long Patch Base Excision Repair
memo: https://reactome.org/content/detail/SPO-5651801
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5651801_PCNA-Dependent_Long_Patch_Base_Excision_Repair


id: SPO-5674499
description: Negative feedback regulation of MAPK pathway
memo: https://reactome.org/content/detail/SPO-5674499
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5674499_Negative_feedback_regulation_of_MAPK_pathway


id: SPO-5685942
description: HDR through Homologous Recombination (HRR)
memo: https://reactome.org/content/detail/SPO-5685942
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5685942_HDR_through_Homologous_Recombination_(HRR)


id: SPO-5693565
memo: https://reactome.org/content/detail/SPO-5693565
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5693565_Recruitment_and_ATM-mediated_phosphorylation_of_repair_and_signaling_proteins_at_DNA_double_strand_breaks

description:
  Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks


id: SPO-5693567
description: HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
memo: https://reactome.org/content/detail/SPO-5693567
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5693567_HDR_through_Homologous_Recombination_(HRR)_or_Single_Strand_Annealing_(SSA)


id: SPO-5693568
description: Resolution of D-loop Structures through Holliday Junction Intermediates
memo: https://reactome.org/content/detail/SPO-5693568
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5693568_Resolution_of_D-loop_Structures_through_Holliday_Junction_Intermediates


id: SPO-5693579
description: Homologous DNA Pairing and Strand Exchange
memo: https://reactome.org/content/detail/SPO-5693579
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5693579_Homologous_DNA_Pairing_and_Strand_Exchange


id: SPO-5693607
description: Processing of DNA double-strand break ends
memo: https://reactome.org/content/detail/SPO-5693607
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5693607_Processing_of_DNA_double-strand_break_ends


id: SPO-5693616
description: Presynaptic phase of homologous DNA pairing and strand exchange
memo: https://reactome.org/content/detail/SPO-5693616
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5693616_Presynaptic_phase_of_homologous_DNA_pairing_and_strand_exchange


id: SPO-5696397
description: Gap-filling DNA repair synthesis and ligation in GG-NER
memo: https://reactome.org/content/detail/SPO-5696397
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5696397_Gap-filling_DNA_repair_synthesis_and_ligation_in_GG-NER


id: SPO-5696399
description: Global Genome Nucleotide Excision Repair (GG-NER)
memo: https://reactome.org/content/detail/SPO-5696399
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-5696399_Global_Genome_Nucleotide_Excision_Repair_(GG-NER)


id: SPO-674695
description: RNA Polymerase II Pre-transcription Events
memo: https://reactome.org/content/detail/SPO-674695
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-674695_RNA_Polymerase_II_Pre-transcription_Events


id: SPO-6781827
description: Transcription-Coupled Nucleotide Excision Repair (TC-NER)
memo: https://reactome.org/content/detail/SPO-6781827
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6781827_Transcription-Coupled_Nucleotide_Excision_Repair_(TC-NER)


id: SPO-6782210
description: Gap-filling DNA repair synthesis and ligation in TC-NER
memo: https://reactome.org/content/detail/SPO-6782210
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6782210_Gap-filling_DNA_repair_synthesis_and_ligation_in_TC-NER


id: SPO-6791226
description: Major pathway of rRNA processing in the nucleolus and cytosol
memo: https://reactome.org/content/detail/SPO-6791226
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6791226_Major_pathway_of_rRNA_processing_in_the_nucleolus_and_cytosol


id: SPO-6791312
description: TP53 Regulates Transcription of Cell Cycle Genes
memo: https://reactome.org/content/detail/SPO-6791312
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6791312_TP53_Regulates_Transcription_of_Cell_Cycle_Genes


id: SPO-6796648
description: TP53 Regulates Transcription of DNA Repair Genes
memo: https://reactome.org/content/detail/SPO-6796648
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6796648_TP53_Regulates_Transcription_of_DNA_Repair_Genes


id: SPO-6803204
description: TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
memo: https://reactome.org/content/detail/SPO-6803204
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6803204_TP53_Regulates_Transcription_of_Genes_Involved_in_Cytochrome_C_Release


id: SPO-6803205
memo: https://reactome.org/content/detail/SPO-6803205
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6803205_TP53_regulates_transcription_of_several_additional_cell_death_genes_whose_specific_roles_in_p53-dependent_apoptosis_remain_uncertain

description:
  TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain


id: SPO-6803207
description: TP53 Regulates Transcription of Caspase Activators and Caspases
memo: https://reactome.org/content/detail/SPO-6803207
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6803207_TP53_Regulates_Transcription_of_Caspase_Activators_and_Caspases


id: SPO-6804115
memo: https://reactome.org/content/detail/SPO-6804115
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6804115_TP53_regulates_transcription_of_additional_cell_cycle_genes_whose_exact_role_in_the_p53_pathway_remain_uncertain

description:
  TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain


id: SPO-6804756
description: Regulation of TP53 Activity through Phosphorylation
memo: https://reactome.org/content/detail/SPO-6804756
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6804756_Regulation_of_TP53_Activity_through_Phosphorylation


id: SPO-6804758
description: Regulation of TP53 Activity through Acetylation
memo: https://reactome.org/content/detail/SPO-6804758
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6804758_Regulation_of_TP53_Activity_through_Acetylation


id: SPO-6806003
description: Regulation of TP53 Expression and Degradation
memo: https://reactome.org/content/detail/SPO-6806003
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6806003_Regulation_of_TP53_Expression_and_Degradation


id: SPO-6807505
description: RNA polymerase II transcribes snRNA genes
memo: https://reactome.org/content/detail/SPO-6807505
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6807505_RNA_polymerase_II_transcribes_snRNA_genes


id: SPO-6811434
description: COPI-dependent Golgi-to-ER retrograde traffic
memo: https://reactome.org/content/detail/SPO-6811434
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6811434_COPI-dependent_Golgi-to-ER_retrograde_traffic


id: SPO-6811436
description: COPI-independent Golgi-to-ER retrograde traffic
memo: https://reactome.org/content/detail/SPO-6811436
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6811436_COPI-independent_Golgi-to-ER_retrograde_traffic


id: SPO-6811440
description: Retrograde transport at the Trans-Golgi-Network
memo: https://reactome.org/content/detail/SPO-6811440
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6811440_Retrograde_transport_at_the_Trans-Golgi-Network


id: SPO-6811442
description: Intra-Golgi and retrograde Golgi-to-ER traffic
memo: https://reactome.org/content/detail/SPO-6811442
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6811442_Intra-Golgi_and_retrograde_Golgi-to-ER_traffic


id: SPO-6811558
description: PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
memo: https://reactome.org/content/detail/SPO-6811558
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6811558_PI5P,_PP2A_and_IER3_Regulate_PI3K/AKT_Signaling


id: SPO-6814122
description: Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
memo: https://reactome.org/content/detail/SPO-6814122
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-6814122_Cooperation_of_PDCL_(PhLP1)_and_TRiC/CCT_in_G-protein_beta_folding


id: SPO-68616
description: Assembly of the ORC complex at the origin of replication
memo: https://reactome.org/content/detail/SPO-68616
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-68616_Assembly_of_the_ORC_complex_at_the_origin_of_replication


id: SPO-68689
description: CDC6 association with the ORC:origin complex
memo: https://reactome.org/content/detail/SPO-68689
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-68689_CDC6_association_with_the_ORC:origin_complex


id: SPO-69017
description: CDK-mediated phosphorylation and removal of Cdc6
memo: https://reactome.org/content/detail/SPO-69017
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-69017_CDK-mediated_phosphorylation_and_removal_of_Cdc6


id: SPO-69052
description: Switching of origins to a post-replicative state
memo: https://reactome.org/content/detail/SPO-69052
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-69052_Switching_of_origins_to_a_post-replicative_state


id: SPO-69202
description: Cyclin E associated events during G1/S transition
memo: https://reactome.org/content/detail/SPO-69202
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-69202_Cyclin_E_associated_events_during_G1/S_transition


id: SPO-69273
description: Cyclin A/B1/B2 associated events during G2/M transition
memo: https://reactome.org/content/detail/SPO-69273
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-69273_Cyclin_A/B1/B2_associated_events_during_G2/M_transition


id: SPO-69601
description: Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
memo: https://reactome.org/content/detail/SPO-69601
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-69601_Ubiquitin_Mediated_Degradation_of_Phosphorylated_Cdc25A


id: SPO-69656
description: Cyclin A:Cdk2-associated events at S phase entry
memo: https://reactome.org/content/detail/SPO-69656
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-69656_Cyclin_A:Cdk2-associated_events_at_S_phase_entry


id: SPO-71406
description: Pyruvate metabolism and Citric Acid (TCA) cycle
memo: https://reactome.org/content/detail/SPO-71406
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-71406_Pyruvate_metabolism_and_Citric_Acid_(TCA)_cycle


id: SPO-72202
description: Transport of Mature Transcript to Cytoplasm
memo: https://reactome.org/content/detail/SPO-72202
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-72202_Transport_of_Mature_Transcript_to_Cytoplasm


id: SPO-72203
description: Processing of Capped Intron-Containing Pre-mRNA
memo: https://reactome.org/content/detail/SPO-72203
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-72203_Processing_of_Capped_Intron-Containing_Pre-mRNA


id: SPO-72662
memo: https://reactome.org/content/detail/SPO-72662
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-72662_Activation_of_the_mRNA_upon_binding_of_the_cap-binding_complex_and_eIFs,_and_subsequent_binding_to_43S

description:
  Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S


id: SPO-72695
description: Formation of the ternary complex, and subsequently, the 43S complex
memo: https://reactome.org/content/detail/SPO-72695
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-72695_Formation_of_the_ternary_complex,_and_subsequently,_the_43S_complex


id: SPO-72702
description: Ribosomal scanning and start codon recognition
memo: https://reactome.org/content/detail/SPO-72702
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-72702_Ribosomal_scanning_and_start_codon_recognition


id: SPO-72706
description: GTP hydrolysis and joining of the 60S ribosomal subunit
memo: https://reactome.org/content/detail/SPO-72706
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-72706_GTP_hydrolysis_and_joining_of_the_60S_ribosomal_subunit


id: SPO-73779
description: RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
memo: https://reactome.org/content/detail/SPO-73779
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-73779_RNA_Polymerase_II_Transcription_Pre-Initiation_And_Promoter_Opening


id: SPO-73817
description: Purine ribonucleoside monophosphate biosynthesis
memo: https://reactome.org/content/detail/SPO-73817
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-73817_Purine_ribonucleoside_monophosphate_biosynthesis


id: SPO-75035
description: Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
memo: https://reactome.org/content/detail/SPO-75035
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-75035_Chk1/Chk2(Cds1)_mediated_inactivation_of_Cyclin_B:Cdk1_complex


id: SPO-75815
description: Ubiquitin-dependent degradation of Cyclin D
memo: https://reactome.org/content/detail/SPO-75815
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-75815_Ubiquitin-dependent_degradation_of_Cyclin_D


id: SPO-75876
description: Synthesis of very long-chain fatty acyl-CoAs
memo: https://reactome.org/content/detail/SPO-75876
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-75876_Synthesis_of_very_long-chain_fatty_acyl-CoAs


id: SPO-76002
description: Platelet activation, signaling and aggregation
memo: https://reactome.org/content/detail/SPO-76002
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-76002_Platelet_activation,_signaling_and_aggregation


id: SPO-76005
description: Response to elevated platelet cytosolic Ca2+
memo: https://reactome.org/content/detail/SPO-76005
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-76005_Response_to_elevated_platelet_cytosolic_Ca2+


id: SPO-76042
description: RNA Polymerase II Transcription Initiation And Promoter Clearance
memo: https://reactome.org/content/detail/SPO-76042
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-76042_RNA_Polymerase_II_Transcription_Initiation_And_Promoter_Clearance


id: SPO-76046
description: RNA Polymerase III Transcription Initiation
memo: https://reactome.org/content/detail/SPO-76046
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-76046_RNA_Polymerase_III_Transcription_Initiation


id: SPO-76061
description: RNA Polymerase III Transcription Initiation From Type 1 Promoter
memo: https://reactome.org/content/detail/SPO-76061
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-76061_RNA_Polymerase_III_Transcription_Initiation_From_Type_1_Promoter


id: SPO-76066
description: RNA Polymerase III Transcription Initiation From Type 2 Promoter
memo: https://reactome.org/content/detail/SPO-76066
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-76066_RNA_Polymerase_III_Transcription_Initiation_From_Type_2_Promoter


id: SPO-77075
description: RNA Pol II CTD phosphorylation and interaction with CE
memo: https://reactome.org/content/detail/SPO-77075
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-77075_RNA_Pol_II_CTD_phosphorylation_and_interaction_with_CE


id: SPO-881907
description: Gastrin-CREB signalling pathway via PKC and MAPK
memo: https://reactome.org/content/detail/SPO-881907
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-881907_Gastrin-CREB_signalling_pathway_via_PKC_and_MAPK


id: SPO-8850843
description: Phosphate bond hydrolysis by NTPDase proteins
memo: https://reactome.org/content/detail/SPO-8850843
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-8850843_Phosphate_bond_hydrolysis_by_NTPDase_proteins


id: SPO-8856825
description: Cargo recognition for clathrin-mediated endocytosis
memo: https://reactome.org/content/detail/SPO-8856825
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-8856825_Cargo_recognition_for_clathrin-mediated_endocytosis


id: SPO-8868773
description: rRNA processing in the nucleus and cytosol
memo: https://reactome.org/content/detail/SPO-8868773
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-8868773_rRNA_processing_in_the_nucleus_and_cytosol


id: SPO-888590
description: GABA synthesis, release, reuptake and degradation
memo: https://reactome.org/content/detail/SPO-888590
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-888590_GABA_synthesis,_release,_reuptake_and_degradation


id: SPO-8948751
description: Regulation of PTEN stability and activity
memo: https://reactome.org/content/detail/SPO-8948751
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-8948751_Regulation_of_PTEN_stability_and_activity


id: SPO-9006925
description: Intracellular signaling by second messengers
memo: https://reactome.org/content/detail/SPO-9006925
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9006925_Intracellular_signaling_by_second_messengers


id: SPO-917729
description: Endosomal Sorting Complex Required For Transport (ESCRT)
memo: https://reactome.org/content/detail/SPO-917729
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-917729_Endosomal_Sorting_Complex_Required_For_Transport_(ESCRT)


id: SPO-948021
description: Transport to the Golgi and subsequent modification
memo: https://reactome.org/content/detail/SPO-948021
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-948021_Transport_to_the_Golgi_and_subsequent_modification


id: SPO-9603798
description: Class I peroxisomal membrane protein import
memo: https://reactome.org/content/detail/SPO-9603798
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9603798_Class_I_peroxisomal_membrane_protein_import


id: SPO-9609523
description: Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
memo: https://reactome.org/content/detail/SPO-9609523
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9609523_Insertion_of_tail-anchored_proteins_into_the_endoplasmic_reticulum_membrane


id: SPO-9615933
description: Postmitotic nuclear pore complex (NPC) reformation
memo: https://reactome.org/content/detail/SPO-9615933
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9615933_Postmitotic_nuclear_pore_complex_(NPC)_reformation


id: SPO-9634600
description: Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
memo: https://reactome.org/content/detail/SPO-9634600
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9634600_Regulation_of_glycolysis_by_fructose_2,6-bisphosphate_metabolism


id: SPO-9634635
description: Estrogen-stimulated signaling through PRKCZ
memo: https://reactome.org/content/detail/SPO-9634635
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9634635_Estrogen-stimulated_signaling_through_PRKCZ


id: SPO-9648025
description: EML4 and NUDC in mitotic spindle formation
memo: https://reactome.org/content/detail/SPO-9648025
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9648025_EML4_and_NUDC_in_mitotic_spindle_formation


id: SPO-964975
description: Vitamins B6 activation to pyridoxal phosphate
memo: https://reactome.org/content/detail/SPO-964975
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-964975_Vitamins_B6_activation_to_pyridoxal_phosphate


id: SPO-9668328
description: Sealing of the nuclear envelope (NE) by ESCRT-III
memo: https://reactome.org/content/detail/SPO-9668328
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9668328_Sealing_of_the_nuclear_envelope_(NE)_by_ESCRT-III


id: SPO-9716542
description: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
memo: https://reactome.org/content/detail/SPO-9716542
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9716542_Signaling_by_Rho_GTPases,_Miro_GTPases_and_RHOBTB3


id: SPO-975138
description: TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
memo: https://reactome.org/content/detail/SPO-975138
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-975138_TRAF6_mediated_induction_of_NFkB_and_MAP_kinases_upon_TLR7/8_or_9_activation


id: SPO-975155
description: MyD88 dependent cascade initiated on endosome
memo: https://reactome.org/content/detail/SPO-975155
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-975155_MyD88_dependent_cascade_initiated_on_endosome


id: SPO-9754119
description: Drug-mediated inhibition of CDK4/CDK6 activity
memo: https://reactome.org/content/detail/SPO-9754119
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9754119_Drug-mediated_inhibition_of_CDK4/CDK6_activity


id: SPO-975871
description: MyD88 cascade initiated on plasma membrane
memo: https://reactome.org/content/detail/SPO-975871
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-975871_MyD88_cascade_initiated_on_plasma_membrane


id: SPO-975956
description: Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
memo: https://reactome.org/content/detail/SPO-975956
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-975956_Nonsense_Mediated_Decay_(NMD)_independent_of_the_Exon_Junction_Complex_(EJC)


id: SPO-975957
description: Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
memo: https://reactome.org/content/detail/SPO-975957
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-975957_Nonsense_Mediated_Decay_(NMD)_enhanced_by_the_Exon_Junction_Complex_(EJC)


id: SPO-9818027
description: NFE2L2 regulating anti-oxidant/detoxification enzymes
memo: https://reactome.org/content/detail/SPO-9818027
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-9818027_NFE2L2_regulating_anti-oxidant/detoxification_enzymes


id: SPO-983168
description: Antigen processing: Ubiquitination & Proteasome degradation
memo: https://reactome.org/content/detail/SPO-983168
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-983168_Antigen_processing:_Ubiquitination_&_Proteasome_degradation


id: SPO-983169
description: Class I MHC mediated antigen processing & presentation
memo: https://reactome.org/content/detail/SPO-983169
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-983169_Class_I_MHC_mediated_antigen_processing_&_presentation


id: SPO-983170
description: Antigen Presentation: Folding, assembly and peptide loading of class I MHC
memo: https://reactome.org/content/detail/SPO-983170
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-983170_Antigen_Presentation:_Folding,_assembly_and_peptide_loading_of_class_I_MHC


id: SPO-983231
description: Factors involved in megakaryocyte development and platelet production
memo: https://reactome.org/content/detail/SPO-983231
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-983231_Factors_involved_in_megakaryocyte_development_and_platelet_production


id: SPO-983695
description: Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
memo: https://reactome.org/content/detail/SPO-983695
name:
  Reactome Pathways.STRING_v12.0_284812_STRINGid_SPO-983695_Antigen_activates_B_Cell_Receptor_(BCR)_leading_to_generation_of_second_messengers


