# geneInfo

ensembl_gene_id: Q10659
symbol: spo14
gene_biotype: protein_coding
description:
  Membrane glycoprotein spo14; Required for the formation of transport vesicles from the ER. This function involves the cytoplasmic domain of the protein, which is thought to interact with the small GTP-binding protein sar1.


ensembl_gene_id: Q10719
symbol: fus1
gene_biotype: protein_coding
description:
  Cell fusion protein fus1; Required for cell fusion. It associates with the pre-zygotic projection tips in conjugating cells; Belongs to the formin homology family. BNI1 subfamily.


ensembl_gene_id: Q10752
symbol: cdc28
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein cdc28; Involved in pre-mRNA splicing. Is required together with ATP and at least one other factor, for the first cleavage-ligation reaction. Functions as a molecular motor in the activation of the precatalytic spliceosome for the first transesterification reaction of pre-mRNA splicing by hydrolyzing ATP to cause the activation of the spliceosome without the occurrence of splicing (By similarity). Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily.


ensembl_gene_id: Q10951
symbol: byr4
gene_biotype: protein_coding
description:
  Protein byr4; Has an essential role in ensuring cytokinesis and septation occur only once during mitosis. It does so by interacting with the ras1 signaling pathways, thereby suppressing them; To yeast BFA1.


ensembl_gene_id: Q10988
symbol: uve1
gene_biotype: protein_coding
description:
  UV-damage endonuclease; Endonuclease for the repair of UV-irradiated DNA. Involved in the excision of cyclobutane pyrimidine dimers (CPD) and 6-4 pyrimidine pyrimidones (6-4PP) which forms the UV damage repair (UVDR) pathway. Functions also in oxidative damage repair in vivo. Provides back-up AP endonuclease activity to apn2 together with apn1. Belongs to the uve1/UvsE family.


ensembl_gene_id: Q10990
symbol: cdt2
gene_biotype: protein_coding
description:
  Cell division cycle protein cdt2; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for DNA replication during mitosis and meiosis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of cdt1 and spd1. Involved in the regulation of mitotic and pre-meiotic S- phase progression.


ensembl_gene_id: Q11004
symbol: wis2
gene_biotype: protein_coding
description:
  40 kDa peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.


ensembl_gene_id: Q11118
symbol: wos2
gene_biotype: protein_coding
description:
  Protein wos2; Cell cycle regulatory protein that interacts with cdc2 in the control of the M-G1 transition.


ensembl_gene_id: Q11120
symbol: ofd1
gene_biotype: protein_coding
description:
  Prolyl 3,4-dihydroxylase ofd1; Prolyl 3,4-dihydroxylase that catalyzes 3,4-dihydroxylation of 'Pro-62' of small ribosomal subunit uS12 (rps23 and rps2302), thereby regulating protein translation termination efficiency. Negative regulator of the stability of the N-terminal transcription factor domain (Sre1N) of sre1 which is released from the membrane and enters the nucleus to activate hypoxic gene expression. Belongs to the TPA1 family.


ensembl_gene_id: Q12126
symbol: mcs6
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase crk1; Protein kinase essential for cell proliferation, where it is required for completion of cytokinesis. Phosphorylates the C-terminal repeat domain (CTD) of RNA polymerase II; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.


ensembl_gene_id: Q12238
symbol: uvi31
gene_biotype: protein_coding
description:
  UV-induced protein uvi31; May be involved in control of cell division, especially during the resumption from cell cycle arrest; Belongs to the BolA/IbaG family.


ensembl_gene_id: Q12381
symbol: prp1
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor prp1; Involved in pre-mRNA splicing. Interacts with prp6 and prp13. May also be involved in the regulation of the G0-G1/G2 transition. Required for pre-spliceosome formation, which is the first step of pre- mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site- 3' splice 3'-exon region.


ensembl_gene_id: Q12701
symbol: ksg1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase ksg1; Involved in the control of sexual development and cell growth under stressed conditions. Phosphorylates AGC kinase gad8 at 'Thr-387', activating gad8 kinase activity and promoting sexual development. Phosphorylates AGC kinase psk1 at 'Ser-248', activating psk1 kinase activity and promoting phosphorylation of ribosomal protein S6.


ensembl_gene_id: Q12702
symbol: pab1
gene_biotype: protein_coding
description:
  Protein phosphatase PP2A regulatory subunit B; Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates.


ensembl_gene_id: Q12705
symbol: ppb1
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2B catalytic subunit; Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Appears to be involved in cytokinesis, mating, transport, nuclear and spindle pole body positioning, and cell shape; Belongs to the PPP phosphatase family. PP-2B subfamily.


ensembl_gene_id: Q12706
symbol: psk1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase psk1; AGC kinase which plays a role in TOR complex 1 (TORC1) signaling pathway which mediates temporal control of cell growth in response to nutrients. Required for phosphorylation of ribosomal protein S6 (rps601/rps602) at 'Ser-235' and 'Ser-236'.


ensembl_gene_id: Q1K9C2
symbol: sir1
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] subunit beta; Catalyzes the reduction of sulfite to sulfide, one of several activities required for the biosynthesis of L-cysteine from sulfate.


ensembl_gene_id: Q1K9C4
symbol: hul5
gene_biotype: protein_coding
description:
  Probable E3 ubiquitin protein ligase C167.07c; Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.


ensembl_gene_id: Q1MTN3
symbol: pic1
gene_biotype: protein_coding
description:
  Inner centromere protein-related protein pic1; Required for chromosome segregation and cytokinesis. Has a role in sister chromatid cohesion and condensation.


ensembl_gene_id: Q1MTN7
symbol: rpm1
gene_biotype: protein_coding
description:
  Exoribonuclease II, mitochondrial; Required for intron-independent turnover and processing of mitochondrial RNA. Participates in 3'-mtRNA processing where it hydrolyzes single-stranded RNA or partially double-stranded RNA with 3'-single-stranded tails; Belongs to the RNR ribonuclease family.


ensembl_gene_id: Q1MTN8
symbol: acl4
gene_biotype: protein_coding
description:
  Probable assembly chaperone of rpl4; Acts as a chaperone for the L4 ribosomal subunit encoded by rpl4A and rpl4B, required for hierarchical ribosome assembly. Shields ribosomal protein L4 until timely release and insertion into the pre- ribosome is possible, once ribosomal protein L18 is present. Belongs to the ACL4 family.


ensembl_gene_id: Q1MTN9
symbol: pcf1
gene_biotype: protein_coding
description:
  Chromatin assembly factor 1 subunit rlf2; Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro. It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. May facilitate the efficient and timely assembly of histones into telomeric chromatin (By similarity); Belongs to the RLF2 family.


ensembl_gene_id: Q1MTP1
symbol: iss9
gene_biotype: protein_coding
description:
  THP3 homolog C2A9.11c; Required for transcription elongation. May also be involved in pre-mRNA splicing (By similarity); Belongs to the THP3 family.


ensembl_gene_id: Q1MTQ0
symbol: brl1
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase brl1; E3 ubiquitin-protein ligase which belongs to the histone H2B ubiquitin ligase complex (HULC) which mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.


ensembl_gene_id: Q1MTQ1
symbol: tea2
gene_biotype: protein_coding
description:
  Kinesin-like protein tea2; Promotes microtubule growth, possibly through interactions with the microtubule end, and is important for establishing and maintaining polarized growth along the long axis of the cell. Acts as a kinesin motor protein that moves along microtubules and is required for proper localization of tea1 and tip1 to the cell tips and microtubules, respectively. ATPase activity stimulated via interaction with mal3. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: Q1MTQ7
symbol: klp9
gene_biotype: protein_coding
description:
  Kinesin-like motor protein 9; Kinesin-like motor protein involved in anaphase B spindle elongation; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: Q1MTQ9
symbol: nip7
gene_biotype: protein_coding
description:
  60S ribosome subunit biogenesis protein nip7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.


ensembl_gene_id: Q1MTR0
symbol: atp23
gene_biotype: protein_coding
description:
  Mitochondrial inner membrane protease atp23; Has a dual role in the assembly of mitochondrial ATPase. Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side. Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity); Belongs to the peptidase M76 family.


ensembl_gene_id: Q1MTR2
symbol: rns1
gene_biotype: protein_coding
description:
  RNA-binding protein with serine-rich domain 1 homolog; Putative component of the spliceosome which enhances the formation of the ATP-dependent A complex of the spliceosome. may participate in mRNA 3'-end cleavage. Also mediates increase of mRNA abundance and translational efficiency (By similarity).


ensembl_gene_id: Q1MTR3
symbol: vid27
gene_biotype: protein_coding
description:
  Vacuolar import and degradation protein 27; Has a role in the negative regulation of gluconeogenesis. Required for vacuolar catabolite degradation of fructose-1,6- bisphosphatase (FBPase) (By similarity); Belongs to the VID27 family.


ensembl_gene_id: Q1MTR4
symbol: cti6
gene_biotype: protein_coding
description:
  Putative histone deacetylase complex subunit cti6; Could be a component of the RPD3C(L) histone deacetylase complex (HDAC).


ensembl_gene_id: Q1MTR8
symbol: svp26
gene_biotype: protein_coding
description:
  Protein svp26; May play a role in retention of a subset of membrane proteins in the early Golgi compartments; Belongs to the SVP26 family.


ensembl_gene_id: Q1RKN3
symbol: tlh2
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase tlh2; Exhibits ATP-dependent 3' to 5' DNA helicase activity and has a role in telomerase-independent telomere maintenance. Represses ade6 at an ectopic site.


ensembl_gene_id: Q2L4W6
symbol: spo5
gene_biotype: protein_coding
description:
  Sporulation-specific protein 5; RNA-binding protein which plays a role in sporulation. Regulates the progression of meiosis I and may function in the vicinity of the Mei2 dot.


ensembl_gene_id: Q42598
symbol: SPAC9E9.06c
gene_biotype: protein_coding
description:
  Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.


ensembl_gene_id: Q4LB35
symbol: fol1
gene_biotype: protein_coding
description:
  6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the central section; belongs to the HPPK family.


ensembl_gene_id: Q4PIR3
symbol: nse2
gene_biotype: protein_coding
description:
  E3 SUMO-protein ligase nse2; Acts as an E3 ligase mediating SUMO/Smt3 attachment to other proteins. Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis. Belongs to the NSE2 family.


ensembl_gene_id: Q50HP3
symbol: spc19
gene_biotype: protein_coding
description:
  DASH complex subunit spc19; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. May be necessary for growth under high osmotic stress.


ensembl_gene_id: Q50HP4
symbol: dad4
gene_biotype: protein_coding
description:
  DASH complex subunit dad4; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. May be necessary for growth under high osmotic stress.


ensembl_gene_id: Q53EK2
symbol: nse1
gene_biotype: protein_coding
description:
  Non-structural maintenance of chromosomes element 1; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis.


ensembl_gene_id: Q5FC18
symbol: sgf11
gene_biotype: protein_coding
description:
  SAGA-associated factor 11; Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA [...]


ensembl_gene_id: Q5WRL1
symbol: mrpl27
gene_biotype: protein_coding
description:
  54S ribosomal protein L27, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL41 family.


ensembl_gene_id: Q65ZA6
symbol: ctf8
gene_biotype: protein_coding
description:
  Chromosome transmission fidelity protein 8; Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment. An RFC-like complex (ctf18-RFC) is formed where ctf18 replaces rfc1 in the RFC complex along with the association of dcc1 and ctf8. This complex is required for efficient establishment of chromosome cohesion during S-phase. Acts as a PCNA loader, loading PCNA onto primed templates.


ensembl_gene_id: Q69Z14
symbol: vma9
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit e; Subunit of the integral membrane V0 complex of vacuolar ATPase (By similarity). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.


ensembl_gene_id: Q6BDR8
symbol: nse4
gene_biotype: protein_coding
description:
  Non-structural maintenance of chromosome element 4; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis. Belongs to the NSE4 family.


ensembl_gene_id: Q6E434
symbol: tbf1
gene_biotype: protein_coding
description:
  Telomeric DNA-binding factor trf1; Binds the telomeric double-stranded TTACAGG repeat and regulates telomere length.


ensembl_gene_id: Q6LA53
symbol: aar2
gene_biotype: protein_coding
description:
  A1 cistron-splicing factor aar2; Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing. Involved in splicing pre-mRNA of the A1 cistron and other genes that are important for cell growth (By similarity); Belongs to the AAR2 family.


ensembl_gene_id: Q76PC3
symbol: mme1
gene_biotype: protein_coding
description:
  Uncharacterized mitochondrial carrier C1442.03; Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.


ensembl_gene_id: Q76PC7
symbol: mti3
gene_biotype: protein_coding
description:
  Probable translation initiation factor, mitochondrial; May be involved in mitochondrial translation initiation. Belongs to the IF-3 family.


ensembl_gene_id: Q76PD2
symbol: SPCC1223.01
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase hel2; Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent degradation.


ensembl_gene_id: Q76PD3
symbol: dbp6
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase dbp6; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.


ensembl_gene_id: Q7LKV3
symbol: sen15
gene_biotype: protein_coding
description:
  Probable tRNA-splicing endonuclease subunit sen15; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of th [...]


ensembl_gene_id: Q7LKX0
symbol: elo1
gene_biotype: protein_coding
description:
  Putative elongation of fatty acids protein 2; May be involved in the synthesis of very long chain fatty acids.


ensembl_gene_id: Q7LKZ6
symbol: SPCC1020.13c
gene_biotype: protein_coding
description:
  Probable phospholipase C1020.13c; Probable phospholipase that hydrolyzes phosphatidic acid. Belongs to the PA-PLA1 family.


ensembl_gene_id: Q7LL14
symbol: msl1
gene_biotype: protein_coding
description:
  Probable U2 small nuclear ribonucleoprotein B'; Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA (By similarity).


ensembl_gene_id: Q7LL15
symbol: sus1
gene_biotype: protein_coding
description:
  Transcription and mRNA export factor sus1; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex required for deubiquitination of  [...]


ensembl_gene_id: Q7LL22
symbol: nsk1
gene_biotype: protein_coding
description:
  Kinetochore protein nsk1; Ensures chromosome alignment and accurate chromosome segregation during mitosis. Promotes proper kinetochore-microtubule (k- MT) interactions during anaphase B. The phosphorylation status of nsk1 affects the proper k-MT coupling, ensuring that it interacts stably only at the correct time during mitosis.


ensembl_gene_id: Q7Z992
symbol: sst6
gene_biotype: protein_coding
description:
  ESCRT-I complex subunit vps23; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity).


ensembl_gene_id: Q7Z996
symbol: pop8
gene_biotype: protein_coding
description:
  Probable ribonucleases P protein subunit pop8; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.


ensembl_gene_id: Q7Z9H9
symbol: fig4
gene_biotype: protein_coding
description:
  Polyphosphoinositide phosphatase; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).


ensembl_gene_id: Q7Z9I1
symbol: pfl4
gene_biotype: protein_coding
description:
  Putative cell agglutination protein pfl4; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belongs to the mam3/map4 family.


ensembl_gene_id: Q86ZU7
symbol: cox1102
gene_biotype: protein_coding
description:
  Cytochrome c oxidase assembly protein cox11-2; Rsm22-2 is involved in mitochondrion-encoded protein synthesis; In the C-terminal section; belongs to the COX11/CtaG family.


ensembl_gene_id: Q874R1
symbol: rho4
gene_biotype: protein_coding
description:
  GTP-binding protein rho4; Required for cell separation. Involved in the regulation of the septum degradation during cytokinesis and in the organization of F- actin patches and cytoplasmic microtubules. Belongs to the small GTPase superfamily. Rho family.


ensembl_gene_id: Q874R3
symbol: apc2
gene_biotype: protein_coding
description:
  Anaphase-promoting complex subunit 2; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome; Belongs to the cullin family.


ensembl_gene_id: Q874R4
symbol: pfl3
gene_biotype: protein_coding
description:
  Putative cell agglutination protein pfl3; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belongs to the mam3/map4 family.


ensembl_gene_id: Q8NIL3
symbol: aes1
gene_biotype: protein_coding
description:
  Antisense-enhancing sequence 1; May have isomerase activity (By similarity). Enhances target gene silencing when coexpressed with antisense RNA.


ensembl_gene_id: Q8TFG0
symbol: SPBPB8B6.02c
gene_biotype: protein_coding
description:
  Probable urea active transporter 2; Involved in active transport of urea; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Q8TFG7
symbol: trm5
gene_biotype: protein_coding
description:
  tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.


ensembl_gene_id: Q8TFG9
symbol: pfl2
gene_biotype: protein_coding
description:
  Putative GPI-anchored protein pfl2; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed.


ensembl_gene_id: Q8TFH3
symbol: ost3
gene_biotype: protein_coding
description:
  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]


ensembl_gene_id: Q8TFH7
symbol: sen2
gene_biotype: protein_coding
description:
  Probable tRNA-splicing endonuclease subunit sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant s [...]


ensembl_gene_id: Q8WZJ7
symbol: thf1
gene_biotype: protein_coding
description:
  C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family.


ensembl_gene_id: Q8WZJ8
symbol: rpc31
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit rpc31; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.


ensembl_gene_id: Q8WZJ9
symbol: hut1
gene_biotype: protein_coding
description:
  UDP-galactose transporter homolog 1; May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen (By similarity). Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum; Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.


ensembl_gene_id: Q8WZK0
symbol: usp107
gene_biotype: protein_coding
description:
  U1 snRNP-associated protein usp107; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.


ensembl_gene_id: Q8WZK2
symbol: its8
gene_biotype: protein_coding
description:
  GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.


ensembl_gene_id: Q8WZK3
symbol: ibp1
gene_biotype: protein_coding
description:
  Dual specificity phosphatase ibp1; May play a role in DNA replication checkpoint via regulation of hsk1 or may act downstream of hsk1 in an S phase regulatory pathway.


ensembl_gene_id: Q8WZK4
symbol: dcn1
gene_biotype: protein_coding
description:
  Defective in cullin neddylation protein 1; May contribute to neddylation of cullin components of SCF- type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).


ensembl_gene_id: Q8WZK5
symbol: aly1
gene_biotype: protein_coding
description:
  Putative arrestin-related trafficking adapter SPBC839.02; May regulate endocytosis in response to extracellular stimuli.


ensembl_gene_id: Q92339
symbol: ght3
gene_biotype: protein_coding
description:
  High-affinity gluconate transporter ght3; High-affinity gluconate transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: Q92341
symbol: str3
gene_biotype: protein_coding
description:
  Siderophore iron transporter 3; Involved in the transport of siderophore iron and so has a role in iron homeostasis; Belongs to the major facilitator superfamily.


ensembl_gene_id: Q92342
symbol: SPAC1F8.04c
gene_biotype: protein_coding
description:
  Uncharacterized protein C1F8.04c; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: Q92344
symbol: pfl8
gene_biotype: protein_coding
description:
  Putative cell agglutination protein pfl8; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed.


ensembl_gene_id: Q92347
symbol: nop9
gene_biotype: protein_coding
description:
  Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family.


ensembl_gene_id: Q92350
symbol: pcd1
gene_biotype: protein_coding
description:
  Probable nudix hydrolase C6G9.05; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily.


ensembl_gene_id: Q92351
symbol: pcp1
gene_biotype: protein_coding
description:
  Spindle pole body protein pcp1; Spindle pole body component that binds calmodulin. Overexpression of pcp1 causes the formation of supernumerary SPB-like structures and disrupts both mitotic spindle assembly and chromosome segregation.


ensembl_gene_id: Q92352
symbol: arc4
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament (By similarity).


ensembl_gene_id: Q92353
symbol: ubp6
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase 6; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Belongs to the peptidase C19 family. USP14/UBP6 subfamily.


ensembl_gene_id: Q92355
symbol: sen1
gene_biotype: protein_coding
description:
  Helicase sen1; ATP-dependent 5'->3' DNA/RNA helicase required for the expression and maturation of diverse classes of non-protein-coding RNAs like precursor tRNAs, rRNAs and small nuclear (snRNA) and nucleolar (snoRNA) RNAs. Directs RNA polymerase II transcription termination on snoRNAs as well as on several short protein-coding genes. May also play a role in transcription-coupled nucleotide excision repair (By similarity).


ensembl_gene_id: Q92356
symbol: syb1
gene_biotype: protein_coding
description:
  Synaptobrevin homolog 1; Involved in membrane trafficking during cytokinesis and cell elongation; Belongs to the synaptobrevin family.


ensembl_gene_id: Q92357
symbol: cfr1
gene_biotype: protein_coding
description:
  Cell fusion protein cfr1; Required for cell fusion, independently of fus1. Appears to have a role in transporting proteins that are involved in mating. May act as a scaffold to retain cell fusion proteins in the cisternae of the Golgi. Degraded at the onset of mating and this leads to release of cell fusion proteins; Belongs to the CHS5 family.


ensembl_gene_id: Q92358
symbol: bqt1
gene_biotype: protein_coding
description:
  Telomere bouquet protein 1; Involved in chromosome segregation. During meiotic prophase, connects telomeres to the spindle pole body by forming a bridge between the telomere protein rap1 and the spindle pole body protein sad1.


ensembl_gene_id: Q92368
symbol: rcd1
gene_biotype: protein_coding
description:
  Cell differentiation protein rcd1; A differentiation-controlling factor that is essential for the onset of sexual development. Induces ste11 when sexual development is invoked through nitrogen starvation.


ensembl_gene_id: Q92370
symbol: trp1
gene_biotype: protein_coding
description:
  Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.


ensembl_gene_id: Q92371
symbol: btf3
gene_biotype: protein_coding
description:
  Nascent polypeptide-associated complex subunit beta; Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the [...]


ensembl_gene_id: Q92372
symbol: ssb1
gene_biotype: protein_coding
description:
  Replication factor A protein 1; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism; Belongs to the replication factor A protein 1 family.


ensembl_gene_id: Q92373
symbol: ssb2
gene_biotype: protein_coding
description:
  Replication factor A protein 2; Binds to single-stranded sequences; Belongs to the replication factor A protein 2 family.


ensembl_gene_id: Q92374
symbol: ssb3
gene_biotype: protein_coding
description:
  Replication factor A protein 3; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.


ensembl_gene_id: Q92376
symbol: pkl1
gene_biotype: protein_coding
description:
  Kinesin-like protein 1; Microtubule-dependent motor that is involved in microtubule organization in the mitotic spindle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily.


ensembl_gene_id: Q92377
symbol: mdm12
gene_biotype: protein_coding
description:
  Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...]


ensembl_gene_id: Q92383
symbol: mag1
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase 1; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3- methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions. Can release ethylated and propylated bases from DNA in addition to 3-methyladenine; Belongs to the alkylbase DNA glycosidase AlkA family.


ensembl_gene_id: Q92398
symbol: pmk1
gene_biotype: protein_coding
description:
  Mitogen-activated protein kinase spm1; Regulates cell integrity and functions coordinately with the protein kinase C pathway (pck1 and pck2). Involved the regulation of wall architecture, cell shape, cytokinesis in exponential and stationary phase, and metabolism of ions.


ensembl_gene_id: Q92399
symbol: rpb8
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.


ensembl_gene_id: Q92462
symbol: pub1
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase pub1; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Regulates ubiquitination of cdc25.


ensembl_gene_id: Q96TL7
symbol: rap1
gene_biotype: protein_coding
description:
  DNA-binding protein rap1; Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE). Unlike yeast, exhibits no effect in transcription regulation. Belongs to the RAP1 family.


ensembl_gene_id: Q96UP3
symbol: rif1
gene_biotype: protein_coding
description:
  Telomere length regulator protein rif1; Negatively regulates telomere length. Appears to play no role in transcriptional silencing of telomeric loci.


ensembl_gene_id: Q96VG2
symbol: ost4
gene_biotype: protein_coding
description:
  Probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase 4 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation  [...]


ensembl_gene_id: Q96WV0
symbol: ure7
gene_biotype: protein_coding
description:
  Uncharacterized urease accessory protein ureG-like; Probably facilitates nickel incorporation; Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.


ensembl_gene_id: Q96WV1
symbol: trm8
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: Q96WV5
symbol: cop1
gene_biotype: protein_coding
description:
  Putative coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).


ensembl_gene_id: Q96WV9
symbol: cdk9
gene_biotype: protein_coding
description:
  Probable cyclin-dependent kinase 9; Component of the positive transcription elongation factor b (P-TEFb) which consists of cdk9 and pch1, and which phosphorylates the C-terminal domain (CTD) of RNA polymerase II and spt5. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.


ensembl_gene_id: Q96WW1
symbol: omh5
gene_biotype: protein_coding
description:
  O-glycoside alpha-1,2-mannosyltransferase homolog 5; Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins; Belongs to the glycosyltransferase 15 family.


ensembl_gene_id: Q96WW6
symbol: alg2
gene_biotype: protein_coding
description:
  Alpha-1,3/1,6-mannosyltransferase alg2; Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.


ensembl_gene_id: Q9C0U7
symbol: vps5
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein vps5; Required for efficient sporulation target of PtdIns(3)P in vesicle transport required for onset of the forespore membrane formation.


ensembl_gene_id: Q9C0V1
symbol: amt1
gene_biotype: protein_coding
description:
  Ammonium transporter 1; Transporter for ammonium to use as a nitrogen source. Under ammonium limitation acts as an ammonium sensor, generating a signal that leads to pseudohyphal growth; Belongs to the ammonia transporter channel (TC 1.A.11.2) family.


ensembl_gene_id: Q9C0W0
symbol: mis15
gene_biotype: protein_coding
description:
  Inner kinetochore subunit mis15; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly. Has a role in the formation and/or maintenance of specialized chromatin at the centromere.


ensembl_gene_id: Q9C0W1
symbol: nrk1
gene_biotype: protein_coding
description:
  Nicotinamide riboside kinase; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN); Belongs to the uridine kinase family. NRK subfamily.


ensembl_gene_id: Q9C0W7
symbol: apl3
gene_biotype: protein_coding
description:
  AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Alpha adaptin is a subunit of the plasma membrane adaptor (By similarity).


ensembl_gene_id: Q9C0W8
symbol: drp1
gene_biotype: protein_coding
description:
  Protein transport protein tip20; Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex (By similarity).


ensembl_gene_id: Q9C0X6
symbol: rvb1
gene_biotype: protein_coding
description:
  RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family.


ensembl_gene_id: Q9C0X8
symbol: rrp12
gene_biotype: protein_coding
description:
  Putative ribosomal RNA-processing protein 12; Required for nuclear export of the ribosomal subunits. Required for maturation of the RNA components of pre-ribosomes (By similarity); Belongs to the RRP12 family.


ensembl_gene_id: Q9C0X9
symbol: npc2
gene_biotype: protein_coding
description:
  Phosphatidylglycerol/phosphatidylinositol transfer protein; Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol; Belongs to the NPC2 family.


ensembl_gene_id: Q9C0Y2
symbol: SPAPB2C8.01
gene_biotype: protein_coding
description:
  Putative cell agglutination protein SPAPB2C8.01; May be involved in agglutination during conjugation or other aspects of colony formation; Belongs to the mam3/map4 family.


ensembl_gene_id: Q9C0Z3
symbol: slx9
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein slx9; Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1) (By similarity). Belongs to the SLX9 family.


ensembl_gene_id: Q9C0Z4
symbol: dop1
gene_biotype: protein_coding
description:
  Protein dopey; Involved in cellular morphogenesis. Required for traffic between late Golgi and early endosomes, and for the normal structure and organization of the endoplasmic reticulum (By similarity). Belongs to the dopey family.


ensembl_gene_id: Q9C0Z9
symbol: rpc17
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit rpc9; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.


ensembl_gene_id: Q9C100
symbol: ogm2
gene_biotype: protein_coding
description:
  Dolichyl-phosphate-mannose--protein mannosyltransferase 2; Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.


ensembl_gene_id: Q9C102
symbol: glt1
gene_biotype: protein_coding
description:
  Putative glutamate synthase [NADPH]; Forms L-glutamate from L-glutamine and 2-oxoglutarate. Represents an alternative pathway to L-glutamate dehydrogenase for the biosynthesis of L-glutamate. Participates with glutamine synthetase in ammonia assimilation processes. The enzyme is specific for NADH, L- glutamine and 2-oxoglutarate (By similarity).


ensembl_gene_id: Q9C103
symbol: eme1
gene_biotype: protein_coding
description:
  Crossover junction endonuclease eme1; Interacts with mus81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI). Belongs to the EME1/MMS4 family.


ensembl_gene_id: Q9C104
symbol: gde1
gene_biotype: protein_coding
description:
  Glycerophosphodiester phosphodiesterase gde1; Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and choline.


ensembl_gene_id: Q9C106
symbol: rpc82
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase III subunit rpc3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).


ensembl_gene_id: Q9C107
symbol: mcl1
gene_biotype: protein_coding
description:
  Minichromosome loss protein 1; Has a role in regulating DNA replication complexes. Acts as a regulator of post DNA replication initiation. Associates with chromatin during G1 and S phases of mitosis. Required for the transcriptional repression of the outer repeats of the centromeric region. Acts as a polymerase alpha replication accessory factor and is important for S- phase DNA damage survival. Plays a role in lagging-strand synthesis and Ozaki fragment processing, in addition to DNA repair.


ensembl_gene_id: Q9C115
symbol: rec25
gene_biotype: protein_coding
description:
  Meiotic recombination protein rec25; Required for correct meiotic chromosome segregation and recombination.


ensembl_gene_id: Q9C1W3
symbol: erg1
gene_biotype: protein_coding
description:
  Probable squalene monooxygenase; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.


ensembl_gene_id: Q9C1W4
symbol: pmp3
gene_biotype: protein_coding
description:
  Plasma membrane proteolipid 3; Plays a role in the regulation of membrane potential. Could mediate a proton leak. Regulated by the spc1-atf1 pathway and so expression is stress-induced; Belongs to the UPF0057 (PMP3) family.


ensembl_gene_id: Q9C1W5
symbol: tim16
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit tim16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (ssc1) via its interaction with PAM18/TIM14. May act by positioning pam18/tim14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family.


ensembl_gene_id: Q9C1W7
symbol: mim1
gene_biotype: protein_coding
description:
  Mitochondrial import protein 1; Required for the assembly of the TOM (translocase of outer membrane) receptor complex, which is responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins; Belongs to the MIM1 family.


ensembl_gene_id: Q9C1W8
symbol: SPBC713.07c
gene_biotype: protein_coding
description:
  Endopolyphosphatase; Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.


ensembl_gene_id: Q9HDU3
symbol: gal10
gene_biotype: protein_coding
description:
  Bifunctional protein gal10; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity); In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: Q9HDU5
symbol: gal7
gene_biotype: protein_coding
description:
  Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.


ensembl_gene_id: Q9HDU6
symbol: pan5
gene_biotype: protein_coding
description:
  Probable 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: Q9HDV1
symbol: say1
gene_biotype: protein_coding
description:
  Putative steryl acetyl hydrolase mug81; Required for the deacetylation of acetylated sterols (By similarity). Has a role in meiosis; Belongs to the 'GDXG' lipolytic enzyme family.


ensembl_gene_id: Q9HDV5
symbol: mrp7
gene_biotype: protein_coding
description:
  54S ribosomal protein L27, mitochondrial; Involved in mitochondrial genome encoded proteins translation.


ensembl_gene_id: Q9HDV6
symbol: mor2
gene_biotype: protein_coding
description:
  Cell polarity protein mor2; Required for the maintenance of cell polarity. Has a role in localizing F-actin at the cell tips; To yeast TAO3/PAG1.


ensembl_gene_id: Q9HDV9
symbol: gcv3
gene_biotype: protein_coding
description:
  Putative glycine cleavage system H protein, mitochondrial; The glycine cleavage system (glycine decarboxylase complex) catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity); Belongs to the GcvH family.


ensembl_gene_id: Q9HDW0
symbol: toc1
gene_biotype: protein_coding
description:
  Target of rapamycin complex 1 subunit toc1; Component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. Tor2 is essential for growth. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression. TORC1 negatively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Represses mating, meiosis and sporulation efficiency by interfering with the functions of the transcrip [...]


ensembl_gene_id: Q9HDW1
symbol: pgs1
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family.


ensembl_gene_id: Q9HDW3
symbol: tfb5
gene_biotype: protein_coding
description:
  General transcription and DNA repair factor IIH subunit tfb5; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has be [...]


ensembl_gene_id: Q9HDW6
symbol: vma5
gene_biotype: protein_coding
description:
  V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).


ensembl_gene_id: Q9HDW7
symbol: pmc1
gene_biotype: protein_coding
description:
  Calcium-transporting ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports the calcium to the vacuole and participates in the control of the cytosolic free calcium.


ensembl_gene_id: Q9HDW8
symbol: grx5
gene_biotype: protein_coding
description:
  Monothiol glutaredoxin-5; Thiol reductase involved in the biogenesis of iron-sulfur clusters. Required for normal iron homeostasis. Required for integrity of mitochondrial DNA. May play a crucial role in responses to nitrosative and osmotic stresses; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: Q9HDW9
symbol: gpi12
gene_biotype: protein_coding
description:
  Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); Belongs to the PIGL family.


ensembl_gene_id: Q9HDX5
symbol: arv1
gene_biotype: protein_coding
description:
  Protein arv1; Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes. Regulates also the sphingolipid metabolism (By similarity); Belongs to the ARV1 family.


ensembl_gene_id: Q9HDX6
symbol: pof15
gene_biotype: protein_coding
description:
  F-box protein pof15; Probable substrate recognition component of a SCF (SKP1-CUL1- F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins.


ensembl_gene_id: Q9HDX9
symbol: mse1
gene_biotype: protein_coding
description:
  Glutamate--tRNA ligase, mitochondrial; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: Q9HDY1
symbol: ase1
gene_biotype: protein_coding
description:
  Anaphase spindle elongation protein 1; Required for anaphase spindle elongation and microtubule bundling in both interphase and mitosis. Has a role in spatial and temporal regulation of septation and cytokinesis and ensures equal partition of segregating sister chromatids. Ensures correct midzone positioning of protein kinase ark1. Acts as a regulatory component at cytokinesis checkpoint where it inhibits nuclear division when actomyosin ring formation is impaired.


ensembl_gene_id: Q9HDY4
symbol: dhx37
gene_biotype: protein_coding
description:
  Putative ATP-dependent RNA helicase PB1A10.06c; Belongs to the DEAD box helicase family. DEAH subfamily.


ensembl_gene_id: Q9HDY9
symbol: mam3
gene_biotype: protein_coding
description:
  M cell-type agglutination protein mam3; M cell-type specific protein involved in agglutination during conjugation; Belongs to the mam3/map4 family.


ensembl_gene_id: Q9HDZ2
symbol: cwh43
gene_biotype: protein_coding
description:
  Protein cwh43; Involved in the maintenance of cell wall integrity. Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation (By similarity); In the N-terminal section; belongs to the PGAP2 family.


ensembl_gene_id: Q9HDZ3
symbol: pth4
gene_biotype: protein_coding
description:
  Meiotically up-regulated gene 82 protein; Has a role in meiosis; Belongs to the prokaryotic/mitochondrial release factor family.


ensembl_gene_id: Q9HDZ6
symbol: dam1
gene_biotype: protein_coding
description:
  DASH complex subunit dam1; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.


ensembl_gene_id: Q9HDZ7
symbol: atg1801
gene_biotype: protein_coding
description:
  Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct atg9 trafficking to the preautophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). Required for the recruitment of the atg5- atg12/atg16 complex [...]


ensembl_gene_id: Q9HDZ9
symbol: qtr3
gene_biotype: protein_coding
description:
  Queuosine salvage protein; Involved in salvaging queuosine. Belongs to the queuosine salvage protein family.


ensembl_gene_id: Q9HE02
symbol: med13
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 13; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.


ensembl_gene_id: Q9HE05
symbol: ufd2
gene_biotype: protein_coding
description:
  Ubiquitin conjugation factor E4; E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly. Binds to cdc48 and elongates mono- and diubiquitinated ERAD substrates presented by the ufd1-npl4-cdc48 (UNC) AAA ATPase complex to a chain length of 4 to 6 ubiquitin moieties. Delivers these polyubiquitinated substrates to downstream ERAD components, which target them to the proteasome. Enhances ubiquitination at 'Lys-48', but not at 'Lys-29' of the Ub moiety.


ensembl_gene_id: Q9HE06
symbol: SPAC20H4.09
gene_biotype: protein_coding
description:
  Putative pre-mRNA-splicing factor ATP-dependent RNA helicase C20H4.09; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA.


ensembl_gene_id: Q9HE08
symbol: mde1
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).


ensembl_gene_id: Q9HE09
symbol: fml2
gene_biotype: protein_coding
description:
  Putative ATP-dependent DNA helicase fml2; Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.


ensembl_gene_id: Q9HE10
symbol: dsc3
gene_biotype: protein_coding
description:
  DSC E3 ubiquitin ligase complex subunit 3; Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. The complex plays also an important role in the multivesicular body (MVB) pathway and functions in a post- endoplasmic reticulum pathway for protein degradation. Belongs to the dsc3 family.


ensembl_gene_id: Q9HE11
symbol: utp5
gene_biotype: protein_coding
description:
  U3 small nucleolar RNA-associated protein 5; Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t- UTPs) (By similarity).


ensembl_gene_id: Q9HE15
symbol: uck2
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase 2; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: Q9HEQ9
symbol: tcg1
gene_biotype: protein_coding
description:
  Single-stranded TG1-3 DNA-binding protein; Binds single-stranded telomeric sequences of the type (TG[1- 3])n in vitro. Has a role in meiosis.


ensembl_gene_id: Q9HFE1
symbol: fet4
gene_biotype: protein_coding
description:
  Low-affinity iron/zinc ion transport protein fet4; Required for Fe(2+) ion low affinity uptake (By similarity). Has a role in zinc uptake under conditions of zinc limitation.


ensembl_gene_id: Q9HFE4
symbol: fmo1
gene_biotype: protein_coding
description:
  Thiol-specific monooxygenase; Flavin-dependent oxidation of thiol-containing compounds. Probably required for the correct folding of disulfide-bonded proteins (By similarity).


ensembl_gene_id: Q9HFE5
symbol: apm1
gene_biotype: protein_coding
description:
  AP-1 complex subunit mu-1; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).


ensembl_gene_id: Q9HFE8
symbol: tra1
gene_biotype: protein_coding
description:
  Transcription-associated protein 1; Essential component of histone acetyltransferase (HAT) complexes, which serves as a target for activators during recruitment of HAT complexes. Essential for vegetative growth. Functions as a component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and SLIK. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activator [...]


ensembl_gene_id: Q9HFF0
symbol: mic10
gene_biotype: protein_coding
description:
  MICOS complex subunit mic10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.


ensembl_gene_id: Q9HFF4
symbol: ppk1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase ppk1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.


ensembl_gene_id: Q9HFF5
symbol: pds5
gene_biotype: protein_coding
description:
  Sister chromatid cohesion protein pds5; Required for the establishment and maintenance of sister chromatid cohesion during S phase. Prevents their formation until eso1 is present. May also have a role during meiosis.


ensembl_gene_id: Q9HFR0
symbol: csn2
gene_biotype: protein_coding
description:
  COP9 signalosome complex subunit 2; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin- protein ligase complexes (By similarity). Required, indirectly, for activation of ribonucleotide reductase through the degradation of the protein spd1, thereby supplying deoxyribonucleotides for DNA replication and repair.


ensembl_gene_id: Q9HGK2
symbol: meu13
gene_biotype: protein_coding
description:
  Homologous-pairing protein 2; Required for proper homologous pairing and efficient cross- over and intragenic recombination during meiosis. Acts indirectly in a process facilitating homologous recombination. Acts during mid- to late-horse-tail period.


ensembl_gene_id: Q9HGK9
symbol: cnp20
gene_biotype: protein_coding
description:
  Inner kinetochore subunit cnp20; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.


ensembl_gene_id: Q9HGL4
symbol: gcd10
gene_biotype: protein_coding
description:
  tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6; Substrate-binding subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.


ensembl_gene_id: Q9HGL5
symbol: tsf1
gene_biotype: protein_coding
description:
  Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: Q9HGL6
symbol: brx1
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein brx1; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.


ensembl_gene_id: Q9HGM2
symbol: get1
gene_biotype: protein_coding
description:
  Protein get1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.


ensembl_gene_id: Q9HGM3
symbol: yta12
gene_biotype: protein_coding
description:
  Mitochondrial respiratory chain complexes assembly protein rca1; Acts as a component of the m-AAA protease complex which is a ATP-dependent metalloprotease mediating degradation of non-assembled mitochondrial inner membrane proteins. The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes. Function both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides (By similarity); In the C-terminal section; belongs to the peptidase M41 family.


ensembl_gene_id: Q9HGM4
symbol: fit1
gene_biotype: protein_coding
description:
  FIT family protein scs3; May be involved in the synthesis of inositol phospholipids from inositol; Belongs to the FIT family.


ensembl_gene_id: Q9HGM5
symbol: dbp8
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase dbp8; ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites. Required for vegetative growth (By similarity); Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.


ensembl_gene_id: Q9HGM8
symbol: pku80
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...]


ensembl_gene_id: Q9HGN1
symbol: gcn2
gene_biotype: protein_coding
description:
  eIF-2-alpha kinase GCN2; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2- alpha/tif211) on 'Ser-52' in response to low amino acid availability. Plays a role as an activator of the general amino acid control (GAAC) pathway required for adapatation to amino acid starvation. Converts phosphorylated eIF-2-alpha/tif211 either to a competitive inhibitor of translation initiation factor eIF-2B, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a tr [...]


ensembl_gene_id: Q9HGN5
symbol: pib1
gene_biotype: protein_coding
description:
  Putative E3 ubiquitin-protein ligase C36B7.05c; Functions as an E3 ubiquitin-protein ligase. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.


ensembl_gene_id: Q9HGN6
symbol: dus1
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.


ensembl_gene_id: Q9HGN7
symbol: sec63
gene_biotype: protein_coding
description:
  Translocation protein sec63; Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and bip1 in a channel-forming translocon complex. A cycle of assembly and disassembly of Sec62/63 complex from sec61 may govern the activity of the translocon. sec63 may affect sec61-polypeptide interactions by increasing the affinity of targeting pathways for sec61 and/or by modifying sec61 to allow more efficient polypeptide interaction. May also be involved in S [...]


ensembl_gene_id: Q9HGP0
symbol: mbx2
gene_biotype: protein_coding
description:
  MADS-box transcription factor pvg4; Acts in transcription regulation. May bind to a MEF2-like typee II promoter sequence.


ensembl_gene_id: Q9HGP5
symbol: acp2
gene_biotype: protein_coding
description:
  F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Competes with formin cdc12 for attachment to the actin filaments barbed ends. Slowly replaces cdc12 on the barbed ends in preparation for filament disassembly during contractile ring constriction.


ensembl_gene_id: Q9HGQ2
symbol: trm401
gene_biotype: protein_coding
description:
  Multisite-specific tRNA:(cytosine-C(5))-methyltransferase trm4a; tRNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in tRNAs at position 34 and 48. Trm4a and trm4b methylate different sets of tRNAs. Also methylates cytosine to m5C at positions (60, 61 and 62) in tRNA(Asp) ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. TRM4 subfamily.


ensembl_gene_id: Q9HGQ3
symbol: cis4
gene_biotype: protein_coding
description:
  Probable zinc transporter cis4; Probable zinc transporter involved in Golgi membrane trafficking through the regulation of zinc homeostasis.


ensembl_gene_id: Q9P371
symbol: sst2
gene_biotype: protein_coding
description:
  AMSH-like protease sst2; Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in the multivesicular body (MVB) sorting pathway. Required for ubiquitin- dependent sorting of proteins into the endosome and subsequent trafficking to the vacuole. May regulate MVB sorting through deubiquitination of ubiquitinated ESCRT proteins; Belongs to the peptidase M67C family.


ensembl_gene_id: Q9P372
symbol: srp14
gene_biotype: protein_coding
description:
  Signal recognition particle subunit srp14; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane.


ensembl_gene_id: Q9P373
symbol: atg4
gene_biotype: protein_coding
description:
  Probable cysteine protease atg4; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Cleaves the C-terminal amino acid of atg8 to reveal a C-terminal glycine. Atg8 ubiquitin-like activity requires the exposure of the glycine at the C- terminus for its conjugation t [...]


ensembl_gene_id: Q9P376
symbol: fcp1
gene_biotype: protein_coding
description:
  RNA polymerase II subunit A C-terminal domain phosphatase; Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.


ensembl_gene_id: Q9P378
symbol: gas1
gene_biotype: protein_coding
description:
  1,3-beta-glucanosyltransferase gas1; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.


ensembl_gene_id: Q9P380
symbol: ptr2
gene_biotype: protein_coding
description:
  Probable peptide transporter ptr2; Uptake of small peptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family.


ensembl_gene_id: Q9P381
symbol: bbl1
gene_biotype: protein_coding
description:
  Putative phosphatidate cytidylyltransferase; Supplies CDP-diacylglycerol, which may play an important role as both a precursor to phosphoinositide biosynthesis in the plasma membrane and as a negative effector of phosphatidylinositol 4-kinase activity, thereby exerting an effect on cell proliferation via a lipid- dependent signal transduction cascade.


ensembl_gene_id: Q9P382
symbol: nup82
gene_biotype: protein_coding
description:
  Nucleoporin nup82; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity).


ensembl_gene_id: Q9P383
symbol: cbc2
gene_biotype: protein_coding
description:
  Nuclear cap-binding protein subunit 2; Component of the CBC complex, which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in maturation, export and degradation of nuclear mRNAs.


ensembl_gene_id: Q9P3A7
symbol: cdc48
gene_biotype: protein_coding
description:
  Cell division cycle protein 48; ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. By recruiting and promoting the degradation of ubiquitinated proteins, plays a role in the ubiquitin fusion degradation (UFD) pathway. Has a role in the endoplasmic reticulum- associated degradation (ERAD) pathway which mediates the cytoplasmic elimination of misfolded proteins exported from the ER. Involved in spindle disassembly. Component of the  [...]


ensembl_gene_id: Q9P3A8
symbol: knd1
gene_biotype: protein_coding
description:
  Cullin-associated NEDD8-dissociated protein 1; Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor (Probable); Belongs to the CAND family.


ensembl_gene_id: Q9P3B2
symbol: rcf2
gene_biotype: protein_coding
description:
  Respiratory supercomplex factor 2 homolog C1565.01; Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.


ensembl_gene_id: Q9P3T7
symbol: SPAC328.09
gene_biotype: protein_coding
description:
  Probable mitochondrial 2-oxodicarboxylate carrier; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: Q9P3T8
symbol: tbc1
gene_biotype: protein_coding
description:
  Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway; Belongs to the TBCC family.


ensembl_gene_id: Q9P3T9
symbol: bsd1
gene_biotype: protein_coding
description:
  Probable metal homeostasis protein bsd1; Required for homeostasis of heavy metal ions such as cadmium, cobalt and copper; Belongs to the BSD2 family.


ensembl_gene_id: Q9P3U4
symbol: dbl4
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase dbl4; Probable ubiquitin-protein ligase involved in the degradation-related ubiquitination of histones. Contributes to the post-translational regulation of histone protein levels by polyubiquitination of excess histones for subsequent degradation.


ensembl_gene_id: Q9P3U9
symbol: urm1
gene_biotype: protein_coding
description:
  Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...]


ensembl_gene_id: Q9P3W1
symbol: tfa1
gene_biotype: protein_coding
description:
  Transcription initiation factor IIE subunit alpha; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).


ensembl_gene_id: Q9P3W2
symbol: atg1803
gene_biotype: protein_coding
description:
  SVP1-like protein 2; Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways; Belongs to the WD repeat SVP1 family.


ensembl_gene_id: Q9P3W4
symbol: dli1
gene_biotype: protein_coding
description:
  Dynein intermediate light chain dil1; Component of the cytoplasmic dynein which acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity). Promotes oscillatory nuclear movement and efficient pairing of homologous centromeres during meiotic prophase. Belongs to the dynein light intermediate chain DYN3 family.


ensembl_gene_id: Q9P3W5
symbol: tel2
gene_biotype: protein_coding
description:
  DNA replication checkpoint protein tel2; Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients. Required for normal entry into S phase. Regulates activation of the DNA replication checkpoint. Required for efficient phosphorylation of mrc1, which is essential for the activation of cds1 kinase. Plays also an important role in genome stability; Belongs to the TEL2 family.


ensembl_gene_id: Q9P4W1
symbol: cox8
gene_biotype: protein_coding
description:
  Cytochrome c oxidase polypeptide VIII, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transme [...]


ensembl_gene_id: Q9P4W7
symbol: apc5
gene_biotype: protein_coding
description:
  Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome; Belongs to the APC5 family.


ensembl_gene_id: Q9P4X1
symbol: pdi4
gene_biotype: protein_coding
description:
  Thioredoxin domain-containing protein C959.05c; Acts as a membrane-bound chaperone in endoplasmic reticulum quality control. Probably facilitates presentation of substrate to membrane-bound components of the degradation machinery (By similarity).


ensembl_gene_id: Q9P4X2
symbol: omh6
gene_biotype: protein_coding
description:
  O-glycoside alpha-1,2-mannosyltransferase homolog 6; Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins; Belongs to the glycosyltransferase 15 family.


ensembl_gene_id: Q9P4X3
symbol: utp7
gene_biotype: protein_coding
description:
  Probable U3 small nucleolar RNA-associated protein 7; Involved in nucleolar processing of pre-18S ribosomal RNA.


ensembl_gene_id: Q9P4X4
symbol: sec17
gene_biotype: protein_coding
description:
  Probable vesicular-fusion protein sec17 homolog; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus; Belongs to the SNAP family.


ensembl_gene_id: Q9P544
symbol: por1
gene_biotype: protein_coding
description:
  Probable mitochondrial outer membrane protein porin; Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules.


ensembl_gene_id: Q9P546
symbol: rps002
gene_biotype: protein_coding
description:
  40S ribosomal protein S0-B; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.


ensembl_gene_id: Q9P5N0
symbol: abc3
gene_biotype: protein_coding
description:
  ATP-binding cassette transporter abc3; Iron-regulated vacuolar ABC-type transporter which may be responsible for mobilizing stored iron from the vacuole to the cytosol in response to iron deficiency.


ensembl_gene_id: Q9P5N1
symbol: pfl7
gene_biotype: protein_coding
description:
  Putative cell-type specific agglutination protein pfl7; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belongs to the mam3/map4 family.


ensembl_gene_id: Q9P5N2
symbol: aat1
gene_biotype: protein_coding
description:
  Amino acid transporter 1; Probable amino acid transporter that may play a role in function in microtubule organization since it causes microtubule defects when overexpressed; Belongs to the amino acid-polyamine-organocation (APC) superfamily.


ensembl_gene_id: Q9P6H9
symbol: reb1
gene_biotype: protein_coding
description:
  DNA-binding protein reb1; DNA-binding protein that recognizes sites within both the enhancer and the promoter of rRNA transcription, as well as upstream of many genes transcribed by RNA polymerase II. Has a role in the termination of RNA polymerase I catalyzed transcription.


ensembl_gene_id: Q9P6I1
symbol: ubc16
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 16; Catalyzes the covalent attachment of ubiquitin to other proteins.


ensembl_gene_id: Q9P6I2
symbol: dug1
gene_biotype: protein_coding
description:
  Cys-Gly metallodipeptidase dug1; Catalytic component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond. Has a Gly-Cys dipeptidase activity. Belongs to the peptidase M20A family.


ensembl_gene_id: Q9P6I5
symbol: guk1
gene_biotype: protein_coding
description:
  Guanylate kinase; Essential for recycling GMP and indirectly, cGMP; Belongs to the guanylate kinase family.


ensembl_gene_id: Q9P6I7
symbol: dea2
gene_biotype: protein_coding
description:
  Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. Also exhibits a low activity towards N(6)- substituted adenines that are commonly known as the plant hormones cytokinins.


ensembl_gene_id: Q9P6I8
symbol: fmd2
gene_biotype: protein_coding
description:
  Zinc-type alcohol dehydrogenase-like protein C1198.01; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: Q9P6J1
symbol: icl1
gene_biotype: protein_coding
description:
  Mitochondrial 2-methylisocitrate lyase; Catalyzes the formation of pyruvate and succinate from 2- methylisocitrate during the metabolism of endogenous propionyl-CoA. Does not act on isocitrate (By similarity); Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.


ensembl_gene_id: Q9P6J2
symbol: pcl1
gene_biotype: protein_coding
description:
  Fe(2+)/Mn(2+) transporter pcl1; Has a role in both calcium and manganese homeostasis. Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals (By similarity).


ensembl_gene_id: Q9P6J8
symbol: SPBC1683.02
gene_biotype: protein_coding
description:
  Uncharacterized deaminase C1683.02; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.


ensembl_gene_id: Q9P6J9
symbol: pho841
gene_biotype: protein_coding
description:
  Putative inorganic phosphate transporter C1683.01; High-affinity transporter for external inorganic phosphate. Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: Q9P6K1
symbol: sft2
gene_biotype: protein_coding
description:
  Protein transport protein sft2; Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex. Can be replaced by got1 (By similarity); Belongs to the SFT2 family.


ensembl_gene_id: Q9P6K5
symbol: dml1
gene_biotype: protein_coding
description:
  Protein dml1; Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance; Belongs to the misato family.


ensembl_gene_id: Q9P6K6
symbol: erv14
gene_biotype: protein_coding
description:
  ER-derived vesicles protein erv14; Regulates export of the secretory proteins from the endoplasmic reticulum in COPII-coated vesicles. Belongs to the cornichon family.


ensembl_gene_id: Q9P6K7
symbol: asc1
gene_biotype: protein_coding
description:
  tRNA-aminoacylation cofactor arc1; Binds to tRNA and functions as a cofactor for the methionyl- tRNA synthetase (MetRS) and glutamyl-tRNA synthetase (GluRS). Forms a complex with MetRS and GluRS and increases their affinity for cognate tRNAs due to the presence of a tRNA binding domain in its middle and C- terminal part (By similarity).


ensembl_gene_id: Q9P6K9
symbol: mmd1
gene_biotype: protein_coding
description:
  Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.


ensembl_gene_id: Q9P6L2
symbol: set13
gene_biotype: protein_coding
description:
  Ribosomal lysine N-methyltransferase 4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that monomethylates 60S ribosomal protein L42 (rpl42) at 'Lys-55'; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.


ensembl_gene_id: Q9P6L5
symbol: end4
gene_biotype: protein_coding
description:
  Endocytosis protein end4; Required for cellular morphogenesis and polarization of the cortical cytoskeleton. Required for establishment of new polarized growth zones where it acts in actin organization. Involved plasma membrane internalization and is essential for fluid-phase endocytosis. Belongs to the SLA2 family.


ensembl_gene_id: Q9P6L6
symbol: rev3
gene_biotype: protein_coding
description:
  DNA polymerase zeta catalytic subunit; Nonessential DNA polymerase. Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Has a role in the bypass of abasic (AP) sites (By similarity).


ensembl_gene_id: Q9P6L8
symbol: srb8
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 12; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.


ensembl_gene_id: Q9P6M0
symbol: slx4
gene_biotype: protein_coding
description:
  Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for stem-loop (SL) and splayed arm Y structures. Introduces a single-strand cut in duplex DNA on the 3' side of a double-strand/single-strand junction with respect to the single-strand moving 3' to 5' away from the junction. Plays a critic [...]


ensembl_gene_id: Q9P6M3
symbol: mis14
gene_biotype: protein_coding
description:
  Kinetochore protein mis14; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Required for correct chromosome segregation where it has a role in the formation and/or maintenance of specialized chromatin at the centromere.


ensembl_gene_id: Q9P6M7
symbol: mug99
gene_biotype: protein_coding
description:
  Meiotically up-regulated gene 99 protein, mitochondrial; Required for correct meiotic chromosome segregation. Appears to also have role in sporulation.


ensembl_gene_id: Q9P6M8
symbol: crp79
gene_biotype: protein_coding
description:
  mRNA export factor crp79; Binds the poly(A) tail of mRNA. Involved in the export of mRNA from the nucleus to the cytoplasm.


ensembl_gene_id: Q9P6N1
symbol: atg1802
gene_biotype: protein_coding
description:
  Autophagy-related protein 21; Required for cytoplasm to vacuole transport (Cvt) vesicles formation and autophagy (By similarity). Has a role in sporulation.


ensembl_gene_id: Q9P6N2
symbol: ptf1
gene_biotype: protein_coding
description:
  Pdp3-interacting factor 1; Component of the mst2 complex which is a highly specific H3 lysine 14 (H3K14) acetyltransferase that functions together with gcn5 to regulate global levels of H3K14 acetylation (H3K14ac), critical for DNA damage checkpoint activation.


ensembl_gene_id: Q9P6N3
symbol: she9
gene_biotype: protein_coding
description:
  Sensitive to high expression protein 9 homolog, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity).


ensembl_gene_id: Q9P6N4
symbol: vps11
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase pep5; Required for vacuolar biogenesis and for trafficking of hydrolase precursors to the vacuole. Mediates transport at the vacuolar membrane where it may be responsible for tethering transport vesicles on the target membranes. Acts as component of the HOPS complex that acts during the docking stage of vacuole fusion. HOPS is an effector for the vacuolar Rab GTPase ypt7 and is required for vacuolar SNARE complex assembly. It remains bound to SNARE complexes after vacuole fusion. Acts as component of the CORVET complex that is required for transport between  [...]


ensembl_gene_id: Q9P6N5
symbol: sgp1
gene_biotype: protein_coding
description:
  Dihydrosphingosine 1-phosphate phosphatase C823.11; Dihydrosphingosine 1-phosphate phosphatase required for efficient ceramide synthesis from exogenous sphingoid bases. Involved in endocytosis and calcium-mediated signaling (By similarity). Belongs to the type 2 lipid phosphate phosphatase family.


ensembl_gene_id: Q9P6N6
symbol: hem25
gene_biotype: protein_coding
description:
  Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.


ensembl_gene_id: Q9P6N8
symbol: rrp3
gene_biotype: protein_coding
description:
  ATP-dependent rRNA helicase rrp3; ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.


ensembl_gene_id: Q9P6N9
symbol: pga3
gene_biotype: protein_coding
description:
  Protein PER1 homolog; Involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI. Required for efficient transport of GPI-anchor proteins (By similarity). Belongs to the PGAP3/PER1 family.


ensembl_gene_id: Q9P6P0
symbol: taf3
gene_biotype: protein_coding
description:
  Transcription initiation factor TFIID subunit 3; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tra [...]


ensembl_gene_id: Q9P6P1
symbol: tlg2
gene_biotype: protein_coding
description:
  t-SNARE affecting a late Golgi compartment protein 2; t-SNARE that functions in transport from the endosome to the late Golgi and on the endocytic pathway; Belongs to the syntaxin family.


ensembl_gene_id: Q9P6P2
symbol: rrp36
gene_biotype: protein_coding
description:
  rRNA biogenesis protein rrp36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).


ensembl_gene_id: Q9P6P9
symbol: pkp1
gene_biotype: protein_coding
description:
  [Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial; Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.


ensembl_gene_id: Q9P6Q0
symbol: med11
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex (PIC) with RNA polymerase II and the general transcription factors. The essential med1 [...]


ensembl_gene_id: Q9P6Q1
symbol: SPAC644.09
gene_biotype: protein_coding
description:
  Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: Q9P6Q2
symbol: utr4
gene_biotype: protein_coding
description:
  Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).


ensembl_gene_id: Q9P6Q3
symbol: bcs1
gene_biotype: protein_coding
description:
  Probable mitochondrial chaperone bcs1; Chaperone necessary for the assembly of mitochondrial respiratory chain complex III; Belongs to the AAA ATPase family. BCS1 subfamily.


ensembl_gene_id: Q9P6Q5
symbol: dut1
gene_biotype: protein_coding
description:
  Probable deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.


ensembl_gene_id: Q9P6Q6
symbol: pct1
gene_biotype: protein_coding
description:
  mRNA-capping enzyme subunit beta; First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end. Belongs to the fungal TPase family.


ensembl_gene_id: Q9P6R1
symbol: vrp1
gene_biotype: protein_coding
description:
  Verprolin; Involved in cytoskeletal organization and cellular growth. May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins such as profilin or proteins possessing SH3 domains. Plays a role in actin patch assembly by enhancing the ability of myo1 to stimulate actin polymerization by the Arp2/3 complex.


ensembl_gene_id: Q9P6R5
symbol: gpi14
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity).


ensembl_gene_id: Q9P6R6
symbol: atp16
gene_biotype: protein_coding
description:
  ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...]


ensembl_gene_id: Q9P6R7
symbol: vts1
gene_biotype: protein_coding
description:
  Protein vts1; RNA-binding protein involved in post-transcriptional regulation through transcript degradation. May be involved in vacuolar protein transport (By similarity).


ensembl_gene_id: Q9P6S0
symbol: gsf2
gene_biotype: protein_coding
description:
  Galactose-specific cell agglutination protein gsf2; Galactose-specific adhesion protein essential for non-sexual flocculation and filamentous growth. Required for adhesion and filamentous growth through recognition of galactose residues on cell surface glycoconjugates. Induces flocculation when overexpressed.


ensembl_gene_id: Q9P6S5
symbol: ask1
gene_biotype: protein_coding
description:
  DASH complex subunit ask1; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. Plays a role in meiosis.


ensembl_gene_id: Q9P6S6
symbol: pga2
gene_biotype: protein_coding
description:
  PGA2-homolog C27.01c; Involved processing and trafficking glycosylated proteins. Belongs to the PGA2 family.


ensembl_gene_id: Q9P771
symbol: prm1
gene_biotype: protein_coding
description:
  Plasma membrane fusion protein prm1; Involved in cell fusion during mating by stabilizing the plasma membrane fusion event; Belongs to the PRM1 family.


ensembl_gene_id: Q9P774
symbol: prp16
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16; Probable ATP-binding RNA helicase involved in pre-mRNA splicing.


ensembl_gene_id: Q9P777
symbol: his2
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: Q9P780
symbol: npl4
gene_biotype: protein_coding
description:
  Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.


ensembl_gene_id: Q9P781
symbol: SPBC1711.09c
gene_biotype: protein_coding
description:
  Golgi apparatus membrane protein tvp38; Golgi membrane protein involved in vesicular trafficking and spindle migration.


ensembl_gene_id: Q9P783
symbol: rrb1
gene_biotype: protein_coding
description:
  Ribosome assembly protein rrb1; Involved in regulation of L3 expression and stability and plays a role in early 60S ribosomal subunit assembly. May be required for proper assembly of pre-ribosomal particles during early ribosome biogenesis, presumably by targeting L3 onto the 35S precursor rRNA (By similarity).


ensembl_gene_id: Q9P786
symbol: mtd1
gene_biotype: protein_coding
description:
  Methylenetetrahydrofolate dehydrogenase [NAD(+)]; Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.


ensembl_gene_id: Q9P790
symbol: swc2
gene_biotype: protein_coding
description:
  SWR complex protein 2; Participates in the catalytic exchange of histone H2A for the H2A variant pht1, an euchromatin-specific factor, leading to chromatin remodeling and changes in transcription of targeted genes.


ensembl_gene_id: Q9P793
symbol: mit1
gene_biotype: protein_coding
description:
  Chromatin remodeling factor mit1; Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).


ensembl_gene_id: Q9P794
symbol: usp103
gene_biotype: protein_coding
description:
  U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. usp103/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.


ensembl_gene_id: Q9P795
symbol: air1
gene_biotype: protein_coding
description:
  Protein air1; Component of the TRAMP (TRF4) and TRAMP5 complexes which have a poly(A) RNA polymerase activity and are involved in a post- transcriptional quality control mechanism limiting inappropriate expression of genetic information. Polyadenylation is required for the degradative activity of the exosome on several of its nuclear RNA substrates like cryptic transcripts generated by RNA polymerase II and III, or hypomethylated pre-tRNAi-Met. Both complexes polyadenylate RNA processing and degradation intermediates of snRNAs, snoRNAs and mRNAs that accumulate in strains lacking a fun [...]


ensembl_gene_id: Q9P797
symbol: nup131
gene_biotype: protein_coding
description:
  Nucleoporin nup131; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.


ensembl_gene_id: Q9P7A0
symbol: sgo1
gene_biotype: protein_coding
description:
  Shugoshin-1; Plays a central role in chromosome cohesion during meiosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by protecting centromeric rec8 from separase degradation during anaphase I.


ensembl_gene_id: Q9P7B3
symbol: sst1
gene_biotype: protein_coding
description:
  Putative cation exchanger C521.04c; Putative cation exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.


ensembl_gene_id: Q9P7B4
symbol: SPAC521.03
gene_biotype: protein_coding
description:
  NADP-dependent 3-hydroxy acid dehydrogenase; NADP-dependent dehydrogenase with broad substrate specificity acting on 3-hydroxy acids. Catalyzes the NADP-dependent oxidation of L- allo-threonine to L-2-amino-3-keto-butyrate, which is spontaneously decarboxylated into aminoacetone. Also acts on D-threonine, L-serine, D-serine, D-3-hydroxyisobutyrate, L-3-hydroxyisobutyrate, D-glycerate and L-glycerate; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Q9P7B5
symbol: wss1
gene_biotype: protein_coding
description:
  DNA-dependent metalloprotease WSS1 homolog; Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (top1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde. Involved in DNA damage response and processing of stalled or collapsed replication forks by removing the covalently trapped top1 from chromatin. DPC proteolysis enables the repair of the lesions via do [...]


ensembl_gene_id: Q9P7B8
symbol: arb1
gene_biotype: protein_coding
description:
  Argonaute-binding protein 1; Component of the argonaute siRNA chaperone (ARC) complex which is required for histone H3K9 methylation, heterochromatin assembly and siRNA generation. The ARC complex contains mostly double- stranded siRNA. Inhibits the release of the siRNA passenger strand from ago1 together with arb2. Inhibits the slicer activity of ago1. Required for swi6 localization to the centromeric repeats.


ensembl_gene_id: Q9P7C3
symbol: mns1
gene_biotype: protein_coding
description:
  Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase; Involved in glycoprotein quality control as it is important for the targeting of misfolded glycoproteins for degradation. It trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2) with low efficiency.


ensembl_gene_id: Q9P7C5
symbol: cwf16
gene_biotype: protein_coding
description:
  Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.


ensembl_gene_id: Q9P7C6
symbol: cwf23
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor cwf23; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity).


ensembl_gene_id: Q9P7C7
symbol: prp11
gene_biotype: protein_coding
description:
  Pre-mRNA-processing ATP-dependent RNA helicase prp11; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.


ensembl_gene_id: Q9P7C8
symbol: sld5
gene_biotype: protein_coding
description:
  DNA replication complex GINS protein sld5; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation and is required for bir1 localization.


ensembl_gene_id: Q9P7C9
symbol: nhm1
gene_biotype: protein_coding
description:
  m7GpppX diphosphatase; Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7- methylguanosine monophosphate (m7GMP). Has no activity towards mRNA molecules longer than 25 nucleotides. May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the do [...]


ensembl_gene_id: Q9P7D2
symbol: SPBP4H10.17c
gene_biotype: protein_coding
description:
  Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity); Belongs to the AB hydrolase superfamily.


ensembl_gene_id: Q9P7D4
symbol: aco2
gene_biotype: protein_coding
description:
  Homocitrate dehydratase, mitochondrial; Catalyzes the reversible dehydration of (R)-homocitrate to cis-homoaconitate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.


ensembl_gene_id: Q9P7D7
symbol: lcf2
gene_biotype: protein_coding
description:
  Long-chain-fatty-acid--CoA ligase 2; Esterification, concomitant with transport, of endogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. Plays an important role in the determination of viability in the stationary phase; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: Q9P7D9
symbol: rsv1
gene_biotype: protein_coding
description:
  Zinc finger protein rsv1; Involved in maintaining cell viability under glucose starvation conditions. May have a role in regulating genes involved in gluconeogenesis.


ensembl_gene_id: Q9P7E0
symbol: qcr10
gene_biotype: protein_coding
description:
  Cytochrome b-c1 complex subunit 10; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the in [...]


ensembl_gene_id: Q9P7F2
symbol: cao1
gene_biotype: protein_coding
description:
  Copper amine oxidase 1; Copper amine oxidase involved in the metabolism of xenobiotic and biogenic amines. Capable of catalyzing the oxidative deamination of primary amines such as ethylamine as alternate sources of nitrogen to support growth.


ensembl_gene_id: Q9P7F3
symbol: amt3
gene_biotype: protein_coding
description:
  Ammonium transporter 3; Transporter for ammonium to use as a nitrogen source. Belongs to the ammonia transporter channel (TC 1.A.11.2) family.


ensembl_gene_id: Q9P7F7
symbol: vps32
gene_biotype: protein_coding
description:
  Vacuolar-sorting protein snf7; Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).


ensembl_gene_id: Q9P7F8
symbol: get3
gene_biotype: protein_coding
description:
  ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]


ensembl_gene_id: Q9P7F9
symbol: ctr5
gene_biotype: protein_coding
description:
  Copper transport protein ctr5; Required for high affinity copper (probably reduced Cu I) transport into the cell.


ensembl_gene_id: Q9P7G4
symbol: oma1
gene_biotype: protein_coding
description:
  Mitochondrial metalloendopeptidase OMA1; Protease that is part of the quality control system in the inner membrane of mitochondria. Cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins (By similarity).


ensembl_gene_id: Q9P7G5
symbol: bos1
gene_biotype: protein_coding
description:
  Protein transport protein bos1; SNARE required for targeting and fusion of ER-derived transport vesicles with the Golgi complex.


ensembl_gene_id: Q9P7G6
symbol: tos4
gene_biotype: protein_coding
description:
  Transcription factor P14E8.02; Probable transcriptional regulatory protein Required for G1/S progression.


ensembl_gene_id: Q9P7G9
symbol: met14
gene_biotype: protein_coding
description:
  Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. Required for methionine synthesis.


ensembl_gene_id: Q9P7H0
symbol: nhp2
gene_biotype: protein_coding
description:
  H/ACA ribonucleoprotein complex subunit nhp2; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 (By similarity). Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs (By similarity). The H/ACA snoRNP complex mediates pseudourid [...]


ensembl_gene_id: Q9P7H1
symbol: clp1
gene_biotype: protein_coding
description:
  Tyrosine-protein phosphatase CDC14 homolog; Protein phosphatase which antagonizes mitotic cyclin- dependent kinase cdc2, the inactivation of which is essential for exit from mitosis. To access its substrates, is released from nucleolar sequestration during mitosis. Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytokinesis checkpoint. Involved in chromosome segregation, where it is required for meiosis I spindle dissambly as well as for establishing two consecutive chromosome segregation phases. Allows damaged actomyosin rings to be maintaine [...]


ensembl_gene_id: Q9P7H2
symbol: rex3
gene_biotype: protein_coding
description:
  RNA exonuclease 3; 3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA; Belongs to the REXO1/REXO3 family.


ensembl_gene_id: Q9P7H3
symbol: phb1
gene_biotype: protein_coding
description:
  Prohibitin-1; Prohibitin probably acts as a holdase/unfoldase for the stabilization of newly synthesized mitochondrial proteins. Has an antiproliferative activity. Regulates replicative life span (By similarity).


ensembl_gene_id: Q9P7H4
symbol: ypa2
gene_biotype: protein_coding
description:
  Serine/threonine-protein phosphatase 2A activator 2; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase. Can reactivate inactive phosphatase PP2A- phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).


ensembl_gene_id: Q9P7H5
symbol: cox24
gene_biotype: protein_coding
description:
  Mitochondrial mRNA-processing protein cox24; May be involved in the splicing of the mitochondrial mRNA. Belongs to the mitochondrion-specific ribosomal protein mS38 family.


ensembl_gene_id: Q9P7H8
symbol: ecm29
gene_biotype: protein_coding
description:
  Proteasome component ecm29; Stabilizes the proteasome holoenzyme, probably by tethering the 20S proteolytic core particle and the 19S regulatory particle. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).


ensembl_gene_id: Q9P7I1
symbol: kha1
gene_biotype: protein_coding
description:
  K(+)/H(+) antiporter 1; Potassium-proton antiport; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Q9P7I2
symbol: cmk1
gene_biotype: protein_coding
description:
  Calcium/calmodulin-dependent protein kinase type I; Important in cell cycle regulation; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.


ensembl_gene_id: Q9P7I3
symbol: mdv1
gene_biotype: protein_coding
description:
  Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family.


ensembl_gene_id: Q9P7I9
symbol: emp24
gene_biotype: protein_coding
description:
  Endosomal protein P24B; Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles. Required for efficient transport of a subset of secretory proteins to the Golgi (By similarity); Belongs to the EMP24/GP25L family.


ensembl_gene_id: Q9P7J2
symbol: xlf1
gene_biotype: protein_coding
description:
  Xrcc4-like factor 1; Involved in non-homologous end joining (NHEJ) in the repair of double-strand DNA breaks (DSB). Has a role in meiosis. Belongs to the XLF family.


ensembl_gene_id: Q9P7J3
symbol: cgi121
gene_biotype: protein_coding
description:
  EKC/KEOPS complex subunit cgi121; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transc [...]


ensembl_gene_id: Q9P7J4
symbol: tho7
gene_biotype: protein_coding
description:
  THO complex subunit mft1; Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase. It functions in cotranscriptional formation of an export- competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-depende [...]


ensembl_gene_id: Q9P7J7
symbol: ada2
gene_biotype: protein_coding
description:
  Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation (gcn5) and deubiquitination (ubp8). SAGA acetylates nu [...]


ensembl_gene_id: Q9P7J8
symbol: gad8
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase gad8; Involved in a signaling module for sexual development and cell growth under stressed conditions. Required for G1 arrest under nitrogen starvation and for growth at high temperature and osmolarity. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.


ensembl_gene_id: Q9P7K0
symbol: tim9
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family.


ensembl_gene_id: Q9P7K5
symbol: git1
gene_biotype: protein_coding
description:
  Adenylate cyclase activation protein git1; Involved in the glucose/cAMP-signaling pathway. Required for maintaining basal cAMP levels and for producing a glucose-triggered cAMP response.


ensembl_gene_id: Q9P7K8
symbol: spt4
gene_biotype: protein_coding
description:
  Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).


ensembl_gene_id: Q9P7L2
symbol: ubx4
gene_biotype: protein_coding
description:
  UBX domain-containing protein 4; Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.


ensembl_gene_id: Q9P7L3
symbol: rib7
gene_biotype: protein_coding
description:
  2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6- ribitylamino-4(3H)-pyrimidinone 5'-phosphate.


ensembl_gene_id: Q9P7L6
symbol: trm140
gene_biotype: protein_coding
description:
  Uncharacterized methyltransferase-like protein SPBC21C3.07c; Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates 3-methylcytidine modification of some tRNAs.


ensembl_gene_id: Q9P7L8
symbol: sap62
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor sap62; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.


ensembl_gene_id: Q9P7M1
symbol: dep1
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein dep1; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity).


ensembl_gene_id: Q9P7M3
symbol: slx1
gene_biotype: protein_coding
description:
  Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for stem-loop (SL) and splayed arm Y structures. Introduces a single-strand cut in duplex DNA on the 3' side of a double-strand/single-strand junction with respect to the single-strand moving 3' to 5' away from the junction. Plays a critica [...]


ensembl_gene_id: Q9P7M5
symbol: nop10
gene_biotype: protein_coding
description:
  H/ACA ribonucleoprotein complex subunit nop10; Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs. The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.


ensembl_gene_id: Q9P7M8
symbol: nup184
gene_biotype: protein_coding
description:
  Nucleoporin nup184; Interacts with pom152 in the core structure of the nuclear pore complex (NPC). Involved in the export of mRNA.


ensembl_gene_id: Q9P7N1
symbol: bud32
gene_biotype: protein_coding
description:
  EKC/KEOPS complex subunit SPAP27G11.07c; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The comp [...]


ensembl_gene_id: Q9P7N2
symbol: vas2
gene_biotype: protein_coding
description:
  AP-1 complex subunit sigma-1; Component of the AP-1 complex which links clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Belongs to the adaptor complexes small subunit family.


ensembl_gene_id: Q9P7N3
symbol: vps41
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 41; Required for vacuolar assembly and vacuolar traffic.


ensembl_gene_id: Q9P7N9
symbol: trs31
gene_biotype: protein_coding
description:
  Transport protein particle subunit trs31; TRAPP plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.


ensembl_gene_id: Q9P7P1
symbol: ker1
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase I subunit rpa14; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. A14 seems to play a role in the stability of Pol I subunit A43 and association of rrn3 to Pol I.


ensembl_gene_id: Q9P7P2
symbol: hop1
gene_biotype: protein_coding
description:
  Meiosis-specific protein hop1; Constituent of the linear elements (LE) during meiosis, the S.pombe equivalents of synaptonemal complexes.


ensembl_gene_id: Q9P7Q2
symbol: pfl9
gene_biotype: protein_coding
description:
  Putative cell agglutination protein pfl9; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed.


ensembl_gene_id: Q9P7Q4
symbol: sec18
gene_biotype: protein_coding
description:
  Vesicular-fusion protein sec18; Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity); Belongs to the AAA ATPase family.


ensembl_gene_id: Q9P7Q6
symbol: mug51
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase mug51; Serine/threonine-protein kinase (By similarity). Has a role in meiosis.


ensembl_gene_id: Q9P7Q7
symbol: mak1
gene_biotype: protein_coding
description:
  Peroxide stress-activated histidine kinase mak1; Involved in the control of the SAPK-dependent transcriptional response to peroxide stress. Also has a role in G2/M regulation.


ensembl_gene_id: Q9P7Q9
symbol: alg9
gene_biotype: protein_coding
description:
  Alpha-1,2-mannosyltransferase alg9; Catalyzes the transfer of mannose from Dol-P-Man to lipid- linked oligosaccharides.


ensembl_gene_id: Q9P7R0
symbol: aro1
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.  In the 3rd section; belongs to the shikimate kinase family.  In the C-terminal section; belongs to the shikimate dehydrogenase family.


ensembl_gene_id: Q9P7R3
symbol: mtr3
gene_biotype: protein_coding
description:
  Exosome complex component mtr3; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [...]


ensembl_gene_id: Q9P7R4
symbol: ubc8
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 8; Catalyzes the covalent attachment of ubiquitin to other proteins; Belongs to the ubiquitin-conjugating enzyme family.


ensembl_gene_id: Q9P7R5
symbol: gfh1
gene_biotype: protein_coding
description:
  Gamma-tubulin complex component gfh1; Required for proper anchoring of astral microtubules at the spindle pole bodies (SPBs), during anaphase, ensuring correct cell polarity; Belongs to the TUBGCP family.


ensembl_gene_id: Q9P7R9
symbol: cwf3
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor cwf3; Involved in pre-mRNA splicing and cell cycle progression. Belongs to the crooked-neck family.


ensembl_gene_id: Q9P7S2
symbol: rpn6
gene_biotype: protein_coding
description:
  Probable 26S proteasome regulatory subunit rpn6; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, rpn6 is required for proteasome assembly (By similarity); Belongs to the proteasome subunit S9 family.


ensembl_gene_id: Q9P7S3
symbol: ssr3
gene_biotype: protein_coding
description:
  SWI/SNF and RSC complexes subunit ssr3; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing bindin [...]


ensembl_gene_id: Q9P7S4
symbol: taf4
gene_biotype: protein_coding
description:
  Transcription initiation factor TFIID subunit 4; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by taf1), facilitation of DNA opening and initiation of tra [...]


ensembl_gene_id: Q9P7S6
symbol: snf30
gene_biotype: protein_coding
description:
  SWI/SNF chromatin-remodeling complex subunit snf30; Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.


ensembl_gene_id: Q9P7S7
symbol: nop58
gene_biotype: protein_coding
description:
  Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family.


ensembl_gene_id: Q9P7S9
symbol: ies4
gene_biotype: protein_coding
description:
  INO80 complex subunit 4; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.


ensembl_gene_id: Q9P7T0
symbol: sib2
gene_biotype: protein_coding
description:
  L-ornithine N(5)-monooxygenase; Catalyzes the conversion of L-ornithine to N(5)- hydroxyornithine, the first step in the biosynthesis of all hydroxamate-containing siderophores, such as ferrichrome. Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)- oxygenase family.


ensembl_gene_id: Q9P7T1
symbol: sib1
gene_biotype: protein_coding
description:
  Hydroxamate-type ferrichrome siderophore peptide synthetase; Involved in intracellular and extracellular ferrichrome siderophore biosynthesis; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: Q9P7T4
symbol: mrc1
gene_biotype: protein_coding
description:
  Mediator of replication checkpoint protein 1; Component of the replisome and is required for rad3-dependent activation of the checkpoint kinase cds1 in response to replication fork arrest. Phosphorylation allows it to mediate the activation of cds1.


ensembl_gene_id: Q9P7T7
symbol: SPAC694.03
gene_biotype: protein_coding
description:
  Putative nicotinamide mononucleotide adenylyltransferase; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Involved in the salvage pathway for NAD(+) biosynthesis via NMN; Belongs to the eukaryotic NMN adenylyltransferase family. POF1 subfamily.


ensembl_gene_id: Q9P7V2
symbol: abc4
gene_biotype: protein_coding
description:
  ATP-binding cassette transporter abc4; Involved in detoxification of xenobiotics, and vacuolar sequestration of glutathione S-conjugates. Together with abc2, required for accumulation of a red pigment (ade pigment) in the vacuole of a mutant affected in the adenine biosynthetic pathway. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.


ensembl_gene_id: Q9P7V3
symbol: tsn1
gene_biotype: protein_coding
description:
  Translin-1; DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations. Selectively binds single-stranded d(GT)n and d(GTT)n microsatellite repeats. Has much higher affinities for the homologous RNA sequences (GU)n and (GUU)n. Does not bind double-stranded DNA. Has a role in meiosis; Belongs to the translin family.


ensembl_gene_id: Q9P7V4
symbol: kti12
gene_biotype: protein_coding
description:
  Protein kti12; Elongator-associated factor that is not a structural subunit but rather transiently contacts Elongator, presumably to promote its interaction with elongation competent pol II. Required for an early step in synthesis of 5-methoxycarbonylmethyl (mcm5) and 5- carbamoylmethyl (ncm5) groups present on uridines at the wobble position in tRNA (By similarity).


ensembl_gene_id: Q9P7V6
symbol: vps33
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 33; Essential for vacuolar biogenesis, maturation and function. Involved in the sorting of vacuolar proteins from the Golgi apparatus and their targeting to the vacuole.


ensembl_gene_id: Q9P7V8
symbol: SPBC1703.13c
gene_biotype: protein_coding
description:
  Probable mitochondrial phosphate carrier protein; Transport of phosphate groups from the cytosol to the mitochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: Q9P7V9
symbol: ubp9
gene_biotype: protein_coding
description:
  Probable ubiquitin carboxyl-terminal hydrolase 9; Ubiquitin C-terminal hydrolase involved in regulating actin dynamics and/or endocytosis at cell tips and septa. Belongs to the peptidase C19 family.


ensembl_gene_id: Q9P7W3
symbol: acl1
gene_biotype: protein_coding
description:
  Probable ATP-citrate synthase subunit 1; Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols. Belongs to the succinate/malate CoA ligase alpha subunit family.


ensembl_gene_id: Q9P7W4
symbol: pof10
gene_biotype: protein_coding
description:
  F-box/WD repeat-containing protein pof10; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.


ensembl_gene_id: Q9P7W5
symbol: rio2
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase rio2; Required for the final endonucleolytic cleavage of 20S pre- rRNA at site D in the cytoplasm, converting it into the mature 18S rRNA. Involved in normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity); Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.


ensembl_gene_id: Q9P7W8
symbol: rsc9
gene_biotype: protein_coding
description:
  Chromatin structure-remodeling complex subunit rsc9; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.


ensembl_gene_id: Q9P7W9
symbol: pop4
gene_biotype: protein_coding
description:
  Probable ribonuclease P protein subunit 1; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.


ensembl_gene_id: Q9P7X0
symbol: tim18
gene_biotype: protein_coding
description:
  Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).


ensembl_gene_id: Q9P7X1
symbol: qcr1
gene_biotype: protein_coding
description:
  Probable mitochondrial-processing peptidase subunit beta; Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (By similarity). Preferentially, cleaves after an arginine at position P2 (By similarity). Belongs to the peptidase M16 family.


ensembl_gene_id: Q9P7X2
symbol: ell1
gene_biotype: protein_coding
description:
  RNA polymerase II elongation factor ell1; Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with eaf1. Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA; Belongs to the ELL/occludin family.


ensembl_gene_id: Q9P7X3
symbol: frg1
gene_biotype: protein_coding
description:
  Protein frg1; May have a role in processing of pre-rRNA or in the assembly of rRNA into ribosomal subunits. May be involved in pre-mRNA splicing (By similarity).


ensembl_gene_id: Q9P7X6
symbol: psf1
gene_biotype: protein_coding
description:
  DNA replication complex GINS protein psf1; The GINS complex plays an essential role in the initiation of DNA replication.


ensembl_gene_id: Q9P7X7
symbol: alp5
gene_biotype: protein_coding
description:
  Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...]


ensembl_gene_id: Q9P7X8
symbol: rpa2
gene_biotype: protein_coding
description:
  Probable DNA-directed RNA polymerase I subunit RPA2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By simi [...]


ensembl_gene_id: Q9P7Y0
symbol: ssr4
gene_biotype: protein_coding
description:
  SWI/SNF and RSC complexes subunit ssr4; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing bindin [...]


ensembl_gene_id: Q9P7Y2
symbol: sdh7
gene_biotype: protein_coding
description:
  Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit sdh2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.


ensembl_gene_id: Q9P7Y3
symbol: pkr1
gene_biotype: protein_coding
description:
  V-type ATPase assembly factor pkr1; Functions together with the other V-type ATPase assembly factors in the endoplasmic reticulum to efficiently assemble the V-type ATPase membrane sector V(0); Belongs to the PKR1 family.


ensembl_gene_id: Q9P7Y4
symbol: med14
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: Q9P7Y8
symbol: mid2
gene_biotype: protein_coding
description:
  Septin ring organizing protein mid2; Responsible for the proper stability and function of septins during cytokinesis. Required for the correct formation of the medial septin ring structure in mitosis and for the proper localization of endo-glucanases agn1 and eng1, which are needed for efficient cell separation. May act as a landmark for the localization of hydrolytic proteins to the medial region.


ensembl_gene_id: Q9P7Y9
symbol: sin1
gene_biotype: protein_coding
description:
  Target of rapamycin complex 2 subunit sin1; Component of TORC2, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC2 is required for cell survival under various stress conditions. TORC2 positively controls G1 cell-cycle arrest, sexual development and amino acid uptake. Positively regulates amino acid uptake through the control of expression of amino acid permeases.


ensembl_gene_id: Q9P7Z3
symbol: efm4
gene_biotype: protein_coding
description:
  Protein-lysine N-methyltransferase efm4; S-adenosyl-L-methionine-dependent protein-lysine N- methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.


ensembl_gene_id: Q9P7Z7
symbol: cox17
gene_biotype: protein_coding
description:
  Cytochrome c oxidase copper chaperone; Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX (By similarity). Belongs to the COX17 family.


ensembl_gene_id: Q9P802
symbol: mis18
gene_biotype: protein_coding
description:
  Kinetochore protein mis18; Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A. Maintains the deacetylated state of histones specifically in the central core of the centromeres. Belongs to the mis18 family.


ensembl_gene_id: Q9P804
symbol: trm1
gene_biotype: protein_coding
description:
  tRNA (guanine(26)-N(2))-dimethyltransferase; Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.


ensembl_gene_id: Q9P805
symbol: dcp1
gene_biotype: protein_coding
description:
  mRNA-decapping enzyme subunit 1; Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense- mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Decapping is the major pathway of mRNA degradation in yeast. It occurs through deadenylation, decapping and subsequent 5' to 3' exonucleolytic decay of the transcript body; Belongs to the DCP1 family.


ensembl_gene_id: Q9UQW6
symbol: erg10
gene_biotype: protein_coding
description:
  Acetyl-CoA acetyltransferase; Catalyzes the formation of acetoacetyl-CoA in the biosynthesis of mevalonate, an intermediate required for the biosynthesis of sterols and nonsterol isoprenoids; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Q9UQW9
symbol: spe1
gene_biotype: protein_coding
description:
  Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.


ensembl_gene_id: Q9UQX0
symbol: sod2
gene_biotype: protein_coding
description:
  Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: Q9UQY2
symbol: pam1
gene_biotype: protein_coding
description:
  Probable proteasome subunit beta type-6; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1B family.


ensembl_gene_id: Q9UQY9
symbol: spo4
gene_biotype: protein_coding
description:
  Cell cycle protein kinase spo4; Required for the initiation of meiosis II and progression through anaphase II.


ensembl_gene_id: Q9UR05
symbol: dlc2
gene_biotype: protein_coding
description:
  Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).


ensembl_gene_id: Q9UR06
symbol: mmf2
gene_biotype: protein_coding
description:
  Protein mmf2, mitochondrial; Plays a role in the maintenance of mitochondrial DNA. Belongs to the RutC family.


ensembl_gene_id: Q9UR09
symbol: psu1
gene_biotype: protein_coding
description:
  Probable secreted beta-glucosidase PSU1; Involved in cell wall synthesis. May be required for the activation of 1,3-beta-glucan synthase; Belongs to the SUN family.


ensembl_gene_id: Q9UR17
symbol: nrf1
gene_biotype: protein_coding
description:
  Vacuolar transporter chaperone 1; Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion (By similarity). Involved in the control of cell polarity.


ensembl_gene_id: Q9UR27
symbol: mrpl31
gene_biotype: protein_coding
description:
  54S ribosomal protein L31, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL60 family.


ensembl_gene_id: Q9UR39
symbol: hst4
gene_biotype: protein_coding
description:
  NAD-dependent protein deacetylase hst4; NAD-dependent histone deacetylase, which contributes to both telomeric and centromeric silencing, proper cell cycle progression, DNA damage control, recombination, and genomic maintenance. Belongs to the sirtuin family. Class I subfamily.


ensembl_gene_id: Q9URM2
symbol: tkt1
gene_biotype: protein_coding
description:
  Probable transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: Q9URT4
symbol: ams2
gene_biotype: protein_coding
description:
  CENP-A multicopy suppressor protein 2; Required for proper chromosome segregation via regulation of CENP-A localization to the centromere.


ensembl_gene_id: Q9URT9
symbol: gsk31
gene_biotype: protein_coding
description:
  Protein kinase gsk31; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.


ensembl_gene_id: Q9URU2
symbol: dna2
gene_biotype: protein_coding
description:
  DNA replication ATP-dependent helicase/nuclease dna2; Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape fen1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit dna2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for fen1. Is a target of the intra-S phase checkpoint, associating with stalled replication forks when phosphorylated at Ser- 219 and preventing the stalled replication forks from reversing. Also involve [...]


ensembl_gene_id: Q9URU4
symbol: pfl5
gene_biotype: protein_coding
description:
  Putative cell agglutination protein pfl5; May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed ; Belongs to the mam3/map4 family.


ensembl_gene_id: Q9URU6
symbol: exg1
gene_biotype: protein_coding
description:
  Glucan 1,3-beta-glucosidase 1; Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity).


ensembl_gene_id: Q9URU9
symbol: gid9
gene_biotype: protein_coding
description:
  Protein fyv10; Involved in the proteasome-dependent degradation of fructose- 1,6-bisphosphatase; Belongs to the FYV10 family.


ensembl_gene_id: Q9URV2
symbol: cut4
gene_biotype: protein_coding
description:
  Anaphase-promoting complex subunit 1; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Mutations to this protein prevent the exit from mitosis; Belongs to the APC1 family.


ensembl_gene_id: Q9URV6
symbol: tim11
gene_biotype: protein_coding
description:
  ATP synthase subunit e, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...]


ensembl_gene_id: Q9URV9
symbol: srx1
gene_biotype: protein_coding
description:
  Sulfiredoxin; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. Belongs to the sulfiredoxin family.


ensembl_gene_id: Q9URW7
symbol: vps17
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 17; Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor pep1/vps10. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The vps29- vps26-vps35 subcomplex may be involved in cargo selection.


ensembl_gene_id: Q9URX3
symbol: SPAC922.03
gene_biotype: protein_coding
description:
  Probable 1-aminocyclopropane-1-carboxylate deaminase; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.


ensembl_gene_id: Q9URX7
symbol: rmt1
gene_biotype: protein_coding
description:
  Protein arginine N-methyltransferase 1; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that catalyzes both the mono- and asymmetric (type I) dimethylation of the guanidino nitrogens of arginine residues in target proteins (By similarity). Asymmetrically dimethylates the polyadenylate-binding protein pab2, modulating pab2 oligomerization.


ensembl_gene_id: Q9URX9
symbol: pxr1
gene_biotype: protein_coding
description:
  Protein pxr1; Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase; Belongs to the PINX1 family.


ensembl_gene_id: Q9URY0
symbol: ytm1
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein ytm1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.


ensembl_gene_id: Q9URY1
symbol: ppk16
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase ppk16; Has a role in meiosis; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.


ensembl_gene_id: Q9URY2
symbol: alp7
gene_biotype: protein_coding
description:
  Microtubule protein alp7; Required for bipolar spindle formation and proper chromosome segregation. Has an indirect role in connecting the kinetochores and the plus end of pole to chromosome microtubules by targeting alp14 to the spindle pole body. Involved in the emergence of large microtubule organizing centers (MTOC) in interphase cells. Attaches to the minus ends of microtubules and associates with the sites of microtubule attachment on the nuclear envelope. This leads to the stabilzation of the microtubule bundles.


ensembl_gene_id: Q9URY3
symbol: tbc13
gene_biotype: protein_coding
description:
  TBC domain-containing protein C1952.17c; May act as a GTPase-activating protein for Rab family protein(s).


ensembl_gene_id: Q9URY5
symbol: yhb1
gene_biotype: protein_coding
description:
  Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the fungus from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity). Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: Q9URY6
symbol: SPAC869.03c
gene_biotype: protein_coding
description:
  Probable urea active transporter 3; Involved in active transport of urea; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Q9URY7
symbol: SPAC869.04
gene_biotype: protein_coding
description:
  Putative formamidase C869.04; Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. May also act on acetamide, propanamide and butanamide (By similarity); Belongs to the acetamidase/formamidase family.


ensembl_gene_id: Q9URY8
symbol: sul2
gene_biotype: protein_coding
description:
  Probable sulfate permease C869.05c; High affinity uptake of sulfate into the cell; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.


ensembl_gene_id: Q9URZ0
symbol: mel1
gene_biotype: protein_coding
description:
  Alpha-galactosidase mel1; Secreted alpha-galactosidase required for catabolic conversion of melibiose to glucose and galactose.


ensembl_gene_id: Q9URZ1
symbol: pcm2
gene_biotype: protein_coding
description:
  Probable protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. This enzyme does not act on D-aspartyl residues (By similarity).


ensembl_gene_id: Q9URZ3
symbol: put4
gene_biotype: protein_coding
description:
  Probable proline-specific permease put4; Required for high-affinity proline transport. May be responsible for proline recognition and probably also for proline translocation across the plasma membrane. Also functions as non- specific GABA permease. Can also transport alanine and glycine (By similarity); Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.


ensembl_gene_id: Q9URZ4
symbol: cat1
gene_biotype: protein_coding
description:
  Cationic amino acid transporter 1; Major permease specifically involved in arginine and lysine uptake.


ensembl_gene_id: Q9URZ5
symbol: vps1
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.


ensembl_gene_id: Q9URZ7
symbol: SPAC732.02c
gene_biotype: protein_coding
description:
  Probable fructose-2,6-bisphosphatase C732.02c; This is predominantly if not solely a fructose-2,6- bisphosphatase; In the C-terminal section; belongs to the phosphoglycerate mutase family.


ensembl_gene_id: Q9URZ8
symbol: vma11
gene_biotype: protein_coding
description:
  V-type proton ATPase 16 kDa proteolipid subunit 2; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).


ensembl_gene_id: Q9US00
symbol: amt2
gene_biotype: protein_coding
description:
  Ammonium transporter 2; Transporter for ammonium to use as a nitrogen source. Belongs to the ammonia transporter channel (TC 1.A.11.2) family.


ensembl_gene_id: Q9US02
symbol: sdh6
gene_biotype: protein_coding
description:
  Succinate dehydrogenase assembly factor 1, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit sdh2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF3.


ensembl_gene_id: Q9US03
symbol: klp2
gene_biotype: protein_coding
description:
  Kinesin-like protein 2; Microtubule-dependent motor that is involved in microtubule organization in the mitotic spindle. Required for the polarization of interphase microtubules where it orients the microtubule plus ends toward the cell ends and the minus ends toward the cell center. Mediates minus end-directed sliding of cytoplasmic microtubules relative to each other, thereby promoting mitotic spindle disassembly. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. NCD subfamily.


ensembl_gene_id: Q9US04
symbol: ggt1
gene_biotype: protein_coding
description:
  Glutathione hydrolase 1 heavy chain; Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides. Major GSH-degrading enzyme, catalyzing the hydrolytic release of L-glutamate from GSH.


ensembl_gene_id: Q9US07
symbol: arp8
gene_biotype: protein_coding
description:
  Probable actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Exhibits low basal ATPase activity, and unable to polymerize. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex (By similarity).


ensembl_gene_id: Q9US08
symbol: spo3
gene_biotype: protein_coding
description:
  Sporulation-specific protein 3; Has a role in spore morphogenesis. Involved in the assembly of the forespore membrane.


ensembl_gene_id: Q9US09
symbol: btn1
gene_biotype: protein_coding
description:
  Protein btn1; Involved in vacuolar transport and vacuole pH homeostasis. Also required for cytokinesis; Belongs to the battenin family.


ensembl_gene_id: Q9US13
symbol: rpn9
gene_biotype: protein_coding
description:
  Probable 26S proteasome regulatory subunit rpn9; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.


ensembl_gene_id: Q9US24
symbol: atg12
gene_biotype: protein_coding
description:
  Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function. The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity). Plays a role in meiosis and sporulation.


ensembl_gene_id: Q9US25
symbol: hrp1
gene_biotype: protein_coding
description:
  Chromodomain helicase hrp1; Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity.


ensembl_gene_id: Q9US26
symbol: fta2
gene_biotype: protein_coding
description:
  Inner kinetochore subunit fta2; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore COMA complex, which connects centromere-associated proteins and the outer kinetochore. COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere- associated network (CCAN), which serves as a structural platform for outer kinetochore assembly. Ft [...]


ensembl_gene_id: Q9US27
symbol: vps66
gene_biotype: protein_coding
description:
  Putative lysophosphatidic acid:oleoyl-CoA acyltransferase; Acyl-CoA-dependent lysophosphatidic acid acyltransferase with preference for oleoyl-CoA. Involved in triacylglyceride homeostasis and lipid droplet formation. Involved in vacuolar protein sorting (By similarity).


ensembl_gene_id: Q9US28
symbol: SPAC1783.01
gene_biotype: protein_coding
description:
  Uncharacterized FAD-binding protein C1783.01; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.


ensembl_gene_id: Q9US35
symbol: SPAC1039.06
gene_biotype: protein_coding
description:
  D-serine dehydratase; Converts specifically D-serine to pyruvate and ammonia. May play a role in D-serine detoxification (By similarity); Belongs to the DSD1 family.


ensembl_gene_id: Q9US36
symbol: klf1
gene_biotype: protein_coding
description:
  Zinc finger protein klf1; Required for maintaining cell viability in nitrogen-deficient stationary phase (G0) cells.


ensembl_gene_id: Q9US43
symbol: urg2
gene_biotype: protein_coding
description:
  Putative uracil phosphoribosyltransferase urg2; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate; Belongs to the UPRTase family.


ensembl_gene_id: Q9US45
symbol: med6
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: Q9US47
symbol: SPAC1002.12c
gene_biotype: protein_coding
description:
  Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP(+)]; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Q9US48
symbol: gaa1
gene_biotype: protein_coding
description:
  GPI transamidase component gaa1; Component of the GPI transamidase complex. Required for a terminal step of GPI anchor attachment onto proteins (By similarity).


ensembl_gene_id: Q9US49
symbol: sgt1
gene_biotype: protein_coding
description:
  Protein ecdysoneless homolog; Involved in the regulation of carbohydrate metabolism. May act as a transcription factor; Belongs to the ECD family.


ensembl_gene_id: Q9US51
symbol: mtf1
gene_biotype: protein_coding
description:
  Mitochondrial transcription factor 1; Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.


ensembl_gene_id: Q9US52
symbol: bqt2
gene_biotype: protein_coding
description:
  Telomere bouquet protein 2; Involved in chromosome segregation. During meiotic prophase, connects telomeres to the spindle pole body by forming a bridge between the telomere protein rap1 and the spindle pole body protein sad1.


ensembl_gene_id: Q9US54
symbol: taf11
gene_biotype: protein_coding
description:
  Transcription initiation factor TFIID subunit 11; Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of tr [...]


ensembl_gene_id: Q9US55
symbol: gls2
gene_biotype: protein_coding
description:
  Glucosidase 2 subunit alpha; Catalytic subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins.


ensembl_gene_id: Q9US59
symbol: skb5
gene_biotype: protein_coding
description:
  Shk1 kinase-binding protein 5; Stimulates catalytic function of the p21-activated kinase homolog shk1.


ensembl_gene_id: Q9US60
symbol: klp3
gene_biotype: protein_coding
description:
  Kinesin-like protein 3; Cytoplasmic motor that could play a role in Golgi membrane recycling; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.


ensembl_gene_id: Q9USD4
symbol: alg12
gene_biotype: protein_coding
description:
  Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation; Belongs to the glycosyltransferase 22 family.


ensembl_gene_id: Q9USG9
symbol: tdp1
gene_biotype: protein_coding
description:
  Probable tyrosyl-DNA phosphodiesterase; DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead- end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. May have low 3'exonuclease activity and may be able to remove a sin [...]


ensembl_gene_id: Q9USH1
symbol: med31
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).


ensembl_gene_id: Q9USH6
symbol: naa40
gene_biotype: protein_coding
description:
  N-alpha-acetyltransferase 40; N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. Belongs to the acetyltransferase family. NAA40 subfamily.


ensembl_gene_id: Q9USH8
symbol: gbs1
gene_biotype: protein_coding
description:
  Glucosidase 2 subunit beta; Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins in the endoplasmic reticulum (ER). Specifically required for the cleavage of the final glucose. The subunit beta retains the catalytic subunit alpha in the ER.


ensembl_gene_id: Q9USI5
symbol: sti1
gene_biotype: protein_coding
description:
  Heat shock protein sti1 homolog; May play a role in mediating the heat shock response of some HSP70 genes.


ensembl_gene_id: Q9USI6
symbol: myo2
gene_biotype: protein_coding
description:
  Myosin type-2 heavy chain 1; Required for cell division. It is a component of the cdc12 'spot', a structure thought to mark the site of septation. May work in conjunction with myo3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.


ensembl_gene_id: Q9USJ1
symbol: tum1
gene_biotype: protein_coding
description:
  Probable 3-mercaptopyruvate sulfurtransferase; Required for formation of the 2-thio group of the 5- methoxycarbonylmethyl-2-thiouridine modified base in some tRNAs.


ensembl_gene_id: Q9USJ2
symbol: got1
gene_biotype: protein_coding
description:
  Protein transport protein got1; Nonessential protein required for the fusion of ER-derived transport vesicles with the Golgi complex. Can be replaced by sft2 (By similarity); Belongs to the GOT1 family.


ensembl_gene_id: Q9USJ4
symbol: nte1
gene_biotype: protein_coding
description:
  Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family.


ensembl_gene_id: Q9USJ5
symbol: hem12
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: Q9USJ6
symbol: SPCC4B3.06c
gene_biotype: protein_coding
description:
  NAD(P)H-dependent FMN reductase C4B3.06c; Has several reductase activities that are NAD(P)H-dependent and involve FMN as a cofactor. May be involved in ferric iron assimilation (By similarity).


ensembl_gene_id: Q9USJ7
symbol: nro1
gene_biotype: protein_coding
description:
  Negative regulator of ofd1; Required for correct translation termination (By similarity). Positive regulator of the stability of the N-terminal transcription factor domain (Sre1N) of sre1 which is released from the membrane and enters the nucleus to activate hypoxic gene expression. Acts also as a direct inhibitor of ofd1. Functions probably by inhibiting the ability of the ofd1 to accelerate Sre1N degradation in absence of oxygen. Belongs to the ETT1 family.


ensembl_gene_id: Q9USJ8
symbol: lsg1
gene_biotype: protein_coding
description:
  CTD kinase subunit gamma; Subunit of the CTDK-I complex, which hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit. As part of the CTDK-I complex, involved in RNA polymerase II transcriptional elongation and pre-mRNA 3'-end processing. Together with ctk2, required for ctk1/lsk1 CTD kinase activation (By similarity).


ensembl_gene_id: Q9USK0
symbol: ipk1
gene_biotype: protein_coding
description:
  Inositol-pentakisphosphate 2-kinase; Has kinase activity and phosphorylates inositol-1,3,4,5,6- pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6- hexakisphosphate (InsP6), also known as phytate; Belongs to the IPK1 type 1 family.


ensembl_gene_id: Q9USK2
symbol: set9
gene_biotype: protein_coding
description:
  Histone-lysine N-methyltransferase set9; Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form H4K20me3. H4 'Lys-20' methylation is apparently not involved in the regulation of gene expression or heterochromatin function but participates in DNA damage response by giving a 'histone mark' required for the recruitment of the checkpoint protein Crb2 to sites of DNA damage.


ensembl_gene_id: Q9USK4
symbol: cwf20
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor cwf20; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.


ensembl_gene_id: Q9USK5
symbol: tip41
gene_biotype: protein_coding
description:
  Type 2A phosphatase activator tip41; Involved in negative regulation of the TOR signaling pathway in response to type of available nitrogen source. Activates the PP2A phosphatase ppa2; Belongs to the TIP41 family.


ensembl_gene_id: Q9USK8
symbol: ags1
gene_biotype: protein_coding
description:
  Cell wall alpha-1,3-glucan synthase ags1; Required for alpha-1,3-glucan and alpha-1,4-glucan production which are required for cell wall synthesis.


ensembl_gene_id: Q9USL4
symbol: nup61
gene_biotype: protein_coding
description:
  Nucleoporin nup61; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. May play a role in mitotic spindle formation and/or function.


ensembl_gene_id: Q9USL5
symbol: dom34
gene_biotype: protein_coding
description:
  Protein dom34; Involved in protein translation. Together with hbs1, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. The complex formed by dom34 and hbs1 has ribonuclease activity towards double-stranded RNA substrates, but does not cleave single-stranded RNA. Acts as endonuclease; has no exonuclease activity. Increases the affinity of hbs1 for GTP, but nor for GDP. Promotes G1 progression and differentiation and is involved in mitotic and meiotic cell divisions [...]


ensembl_gene_id: Q9USL6
symbol: SPCC18B5.05c
gene_biotype: protein_coding
description:
  Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase C18B5.05c; Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. Belongs to the ThiD family.


ensembl_gene_id: Q9USM1
symbol: rpn1302
gene_biotype: protein_coding
description:
  Probable proteasomal ubiquitin receptor ADRM1 homolog; May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity); Belongs to the ADRM1 family.


ensembl_gene_id: Q9USM3
symbol: sfh1
gene_biotype: protein_coding
description:
  Chromatin structure-remodeling complex subunit sfh1; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.


ensembl_gene_id: Q9USM4
symbol: luc7
gene_biotype: protein_coding
description:
  U1 snRNP-associated protein usp106; Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.


ensembl_gene_id: Q9USM6
symbol: oca8
gene_biotype: protein_coding
description:
  Probable cytochrome b5 2; Membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases; Belongs to the cytochrome b5 family.


ensembl_gene_id: Q9USM7
symbol: tim23
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit tim23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.


ensembl_gene_id: Q9USM8
symbol: atg20
gene_biotype: protein_coding
description:
  Autophagy-related protein 20; Required for cytoplasm to vacuole transport (Cvt), pexophagy and mitophagy. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Functions in protein retrieval from the endocytic pathway (By similarity).


ensembl_gene_id: Q9USM9
symbol: coq10
gene_biotype: protein_coding
description:
  Coenzyme Q-binding protein coq10, mitochondrial; Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes (By similarity).


ensembl_gene_id: Q9USN0
symbol: gpi10
gene_biotype: protein_coding
description:
  GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).


ensembl_gene_id: Q9USN3
symbol: utp13
gene_biotype: protein_coding
description:
  Probable U3 small nucleolar RNA-associated protein 13; Involved in nucleolar processing of pre-18S ribosomal RNA.


ensembl_gene_id: Q9USN5
symbol: gdh2
gene_biotype: protein_coding
description:
  Probable NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: Q9USN7
symbol: hst2
gene_biotype: protein_coding
description:
  NAD-dependent protein deacetylase hst2; NAD-dependent histone deacetylase, which could function in telomeric silencing, cell cycle progression and chromosome stability. Belongs to the sirtuin family. Class I subfamily.


ensembl_gene_id: Q9USN8
symbol: rqc2
gene_biotype: protein_coding
description:
  Ribosome quality control complex subunit 2; Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Mtr1/rqc2 is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. Mtr1/rqc2 is important for the stable association of rkr1/ltn1 to the complex. Mtr1/rqc2 recruits alanine- and threonine-charged tRNA to the A site and directs the elongation of stalled nascent chains inde [...]


ensembl_gene_id: Q9USP0
symbol: gcn3
gene_biotype: protein_coding
description:
  Translation initiation factor eIF-2B subunit alpha; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP.


ensembl_gene_id: Q9USP1
symbol: elp4
gene_biotype: protein_coding
description:
  Elongator complex protein 4; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation (By similarity). The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5- carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs ; Belongs to the ELP4 family.


ensembl_gene_id: Q9USP2
symbol: ynd1
gene_biotype: protein_coding
description:
  Golgi apyrase; Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates. Required for Golgi glycosylation and cell wall integrity. Involved in N-mannosylation of proteins in Golgi.


ensembl_gene_id: Q9USP3
symbol: ppr6
gene_biotype: protein_coding
description:
  Pentatricopeptide repeat-containing protein 6, mitochondrial; Mitochondrial RNA-binding protein required for the stability of the atp9 mRNA.


ensembl_gene_id: Q9USP5
symbol: gpi8
gene_biotype: protein_coding
description:
  GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein (By similarity).


ensembl_gene_id: Q9USP6
symbol: clc1
gene_biotype: protein_coding
description:
  Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.


ensembl_gene_id: Q9USP8
symbol: idh2
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial; Performs an essential role in the oxidative function of the citric acid cycle and is involved in glutamate biosynthesis. Also binds RNA; specifically to the 5'-untranslated leaders of mitochondrial mRNAs.


ensembl_gene_id: Q9USQ0
symbol: nem2
gene_biotype: protein_coding
description:
  Sporulation-specific protein spo7; Probable regulatory component of the nem1-spo7 complex which acts as a phosphatase and may be required for proper nuclear membrane morphology.


ensembl_gene_id: Q9USQ1
symbol: ctf18
gene_biotype: protein_coding
description:
  Chromosome transmission fidelity protein 18; Essential for the fidelity of chromosome transmission. Required for the DNA replication block checkpoint. Replication factor C (RFC) complex has an essential but redundant activity in sister chromatid cohesion establishment. Acts as a PCNA loader, loading PCNA onto primed templates. An RFC-like complex (ctf18-RFC) is formed where ctf18 replaces rfc1 in the RFC complex along with the association of dcc1 and ctf8. This complex is required for efficient establishment of chromosome cohesion during S-phase.


ensembl_gene_id: Q9USQ2
symbol: alp6
gene_biotype: protein_coding
description:
  Spindle pole body component alp6; Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles; Belongs to the TUBGCP family.


ensembl_gene_id: Q9USQ4
symbol: sim3
gene_biotype: protein_coding
description:
  NASP-related protein sim3; Histone H3 and H3-like CENP-A-specific chaperone. Promotes delivery and incorporation of CENP-A in centromeric chromatin, probably by escorting nascent CENP-A to CENP-A chromatin assembly factors. Required for central core silencing and normal chromosome segregation.


ensembl_gene_id: Q9USQ5
symbol: spa1
gene_biotype: protein_coding
description:
  Ornithine decarboxylase antizyme; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.


ensembl_gene_id: Q9USQ6
symbol: syj2
gene_biotype: protein_coding
description:
  Inositol-1,4,5-trisphosphate 5-phosphatase 2; Controls the cellular levels and subcellular distribution of phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5- bisphosphate. Involved in distinct membrane trafficking and signal transduction pathways. Highly active against a range of soluble and lipid inositol phosphates. Active in dephosphorylating the 5-position of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 and to a lesser extent Ins(1,4,5,6)P4 (By similarity); In the central section; belongs to the inositol 1,4,5- trisphosphate 5-phosphatase family.


ensembl_gene_id: Q9USQ7
symbol: dph6
gene_biotype: protein_coding
description:
  Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor eEF-2 (eft201 or eft202) to diphthamide (By similarity). Has a role in meiosis; In the N-terminal section; belongs to the Diphthine-- ammonia ligase family.


ensembl_gene_id: Q9USQ9
symbol: pre4
gene_biotype: protein_coding
description:
  Probable proteasome subunit beta type-7; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1B family.


ensembl_gene_id: Q9USR0
symbol: ckn1
gene_biotype: protein_coding
description:
  DNA excision repair protein ckn1; Adapter protein for ddb1/cullin 4 ubiquitin ligases involved in transcription-coupled nucleotide excision repair.


ensembl_gene_id: Q9USR2
symbol: ubp10
gene_biotype: protein_coding
description:
  Probable mRNA-splicing protein ubp10; May play a role in mRNA splicing. It is unsure if the protein really exhibits hydrolase activity. Could be a competitor of ubiquitin C-terminal hydrolases (UCHs) (By similarity); Belongs to the peptidase C19 family.


ensembl_gene_id: Q9USR3
symbol: stt4
gene_biotype: protein_coding
description:
  Phosphatidylinositol 4-kinase stt4; Acts on phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol 1,4,5,- trisphosphate.


ensembl_gene_id: Q9USR4
symbol: rec27
gene_biotype: protein_coding
description:
  Meiotic recombination protein rec27; Required for correct meiotic chromosome segregation and recombination.


ensembl_gene_id: Q9USR9
symbol: cnp3
gene_biotype: protein_coding
description:
  Inner kinetochore subunit cnp3; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.


ensembl_gene_id: Q9USS0
symbol: pnc1
gene_biotype: protein_coding
description:
  Nicotinamidase; Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway; Belongs to the isochorismatase family.


ensembl_gene_id: Q9UST1
symbol: ppk26
gene_biotype: protein_coding
description:
  PAN2-PAN3 deadenylation complex subunit pan3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pab1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exo [...]


ensembl_gene_id: Q9UST2
symbol: mmp2
gene_biotype: protein_coding
description:
  Mitochondrial inner membrane protease subunit 2; Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.


ensembl_gene_id: Q9UST3
symbol: vps52
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 52; Involved in retrograde transport from early and late endosomes to late Golgi by linking the vesicle through the t-SNARE TGL1 to the Golgi, leading to the membrane fusion between late Golgi and endosomal vesicles.


ensembl_gene_id: Q9UST4
symbol: tif512
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis (By similarity); Belongs to the eIF-5A family.


ensembl_gene_id: Q9UST5
symbol: rrn7
gene_biotype: protein_coding
description:
  RNA polymerase I-specific transcription initiation factor rrn7; Component of RNA polymerase I core factor complex (CF) that acts as a sua7/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds HomolD box in rDNA promoters and plays a role in Pol I recruitment; Belongs to the RRN7/TAF1B family.


ensembl_gene_id: Q9UST6
symbol: spc24
gene_biotype: protein_coding
description:
  Kinetochore protein spc24; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Belongs to the SPC24 family.


ensembl_gene_id: Q9UST7
symbol: sfc3
gene_biotype: protein_coding
description:
  Transcription factor tau subunit sfc3; TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauB domain of TFIIIC that binds boxB DNA promoter sites of tRNA and similar genes. Cooperates with sfc6 in DNA binding. Localizes to chromatin insulator sequence without recruiting RNA polymerase III and plays a role in nuclear organization.


ensembl_gene_id: Q9UST9
symbol: hen1
gene_biotype: protein_coding
description:
  Small RNA 2'-O-methyltransferase; Methyltransferase that adds a 2'-O-methyl group at the 3'-end of small RNAs; Belongs to the methyltransferase superfamily. HEN1 family.


ensembl_gene_id: Q9USU1
symbol: efc25
gene_biotype: protein_coding
description:
  Ras guanine nucleotide exchange factor efc25; Has a role in chromosome segregation and cell morphology upstream of the ras1-scd1 pathway. Promotes the exchange of ras1-bound GDP by GTP leading to its activation.


ensembl_gene_id: Q9USU2
symbol: cdh1
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.


ensembl_gene_id: Q9USU3
symbol: fbh1
gene_biotype: protein_coding
description:
  F-box DNA helicase protein 1; Involved in ATP-dependent DNA-unwinding in a 3' to 5' direction, and ATP-ase activities stimulated by the single-stranded DNA-binding protein ssb1. Essential for viability and normal growth of stationary phase cells and in the absence of either srs2 or rqh1 DNA helicase. Involved in DNA recombination repair of strand breaks and stalled or collapsed replication forks, on the rhp51-dependent pathway: promotes rhp51 filament dissolution from stalled forks, thereby inhibiting homologous recombination and preventing excessive recombination. Ubiquitination and D [...]


ensembl_gene_id: Q9USU5
symbol: gas2
gene_biotype: protein_coding
description:
  1,3-beta-glucanosyltransferase gas2; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall; Belongs to the glycosyl hydrolase 72 family.


ensembl_gene_id: Q9USU8
symbol: ngg1
gene_biotype: protein_coding
description:
  Chromatin-remodeling complexes subunit ngg1; Transcription regulator. Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, SLIK and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation of a subset of genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through hist [...]


ensembl_gene_id: Q9USU9
symbol: toa1
gene_biotype: protein_coding
description:
  Transcription initiation factor IIA large subunit; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with tbp mediates transcriptional activity (By similarity).


ensembl_gene_id: Q9USV0
symbol: hrd3
gene_biotype: protein_coding
description:
  Putative ERAD-associated E3 ubiquitin-protein ligase component; Component of the endoplasmic reticulum quality control (ERQC) system involved in ubiquitin-dependent degradation of missfolded endoplasmic reticulum proteins; Belongs to the sel-1 family.


ensembl_gene_id: Q9USV1
symbol: sfr1
gene_biotype: protein_coding
description:
  Swi5-dependent recombination DNA repair protein 1; Involved in DNA recombination repair and meiotic chromosome segregation; Belongs to the SFR1/MEI5 family.


ensembl_gene_id: Q9USV4
symbol: mep33
gene_biotype: protein_coding
description:
  mRNA export protein 33; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. Involved in the export of mRNA from the nucleus to the cytoplasm. May play a role in mito [...]


ensembl_gene_id: Q9USV6
symbol: cbp4
gene_biotype: protein_coding
description:
  Assembly factor cbp4; Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity). Belongs to the CBP4 family.


ensembl_gene_id: Q9USV7
symbol: ctr6
gene_biotype: protein_coding
description:
  Copper transport protein ctr6; Mobilizes stored copper from the vacuole to the cytoplasm under conditions of copper limitation; Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.


ensembl_gene_id: Q9USW2
symbol: inp2
gene_biotype: protein_coding
description:
  Inheritance of peroxisomes protein 2; Required for peroxisome inheritance. Acts as the peroxisome- specific receptor for the myosin V motor myo2 (By similarity). Belongs to the INP2 family.


ensembl_gene_id: Q9USW6
symbol: dpm2
gene_biotype: protein_coding
description:
  Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Essential for the ER localization and stable expression of dpm1 (By similarity).


ensembl_gene_id: Q9USW9
symbol: sgf29
gene_biotype: protein_coding
description:
  SAGA-associated factor 29; Chromatin reader component of the transcription regulatory histone acetylation (HAT) complex SAGA. Sgf29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA complex, sgf29 is required to facilitate crosstalk between gcn5 acetyltransferase activity and H3K4me3 recognition. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and  [...]


ensembl_gene_id: Q9USX0
symbol: pvg3
gene_biotype: protein_coding
description:
  Beta-1,3-galactosyltransferase pvg3; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has a role in meiosis.


ensembl_gene_id: Q9USX3
symbol: rad60
gene_biotype: protein_coding
description:
  DNA repair protein rad60; Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids. This has a subsequent role in the maintenance of chromosome structure. May work in conjunction with the Smc5-Smc6 complex.


ensembl_gene_id: Q9USX8
symbol: lea1
gene_biotype: protein_coding
description:
  U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA (By similarity).


ensembl_gene_id: Q9USY1
symbol: SPBC1861.05
gene_biotype: protein_coding
description:
  Pseudouridine-metabolizing bifunctional protein C1861.05; Bifunctional enzyme that catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP), and the reversible cleavage of pseudouridine 5'-phosphate to ribose 5-phosphate and uracil. Is involved in a pseudouridine degradation pathway. In the C-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: Q9USY3
symbol: naa35
gene_biotype: protein_coding
description:
  N-alpha-acetyltransferase 35, NatC auxiliary subunit; Component of the NatC N-terminal acetyltransferase. Belongs to the MAK10 family.


ensembl_gene_id: Q9USY4
symbol: abp2
gene_biotype: protein_coding
description:
  ARS-binding protein 2; Binds, preferentially, to the Maundrell ARS consensus sequence within ARS3002.


ensembl_gene_id: Q9USY7
symbol: fzo1
gene_biotype: protein_coding
description:
  Transmembrane GTPase fzo1; Probable transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondrial morphology, which is balanced between fusion and fission (By similarity).


ensembl_gene_id: Q9USZ0
symbol: trm734
gene_biotype: protein_coding
description:
  Uncharacterized WD repeat-containing protein C1306.02; May play a role in the regulation of the retromer complex and in the recycling from endosomes of plasma membrane proteins. May be involved in the methylation of the 2'-O-ribose of nucleotides at position 34 of the tRNA anticodon loop of tRNA(Phe) and tRNA(Leu(UAA)) by SPAC4F10.03c (By similarity); Belongs to the WD repeat WDR6 family.


ensembl_gene_id: Q9USZ1
symbol: mef1
gene_biotype: protein_coding
description:
  Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.


ensembl_gene_id: Q9USZ3
symbol: sme1
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein E; Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification (By similarity).


ensembl_gene_id: Q9USZ4
symbol: rpa34
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase I subunit rpa34; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors (By similarity).


ensembl_gene_id: Q9USZ5
symbol: trs20
gene_biotype: protein_coding
description:
  Transport protein particle 20 kDa subunit; Component of the TRAPP I and TRAPP II complexes. TRAPP I plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. TRAPP II seems to play a role in intra-Golgi transport (By similarity); Belongs to the TRAPP small subunits family. Sedlin subfamily.


ensembl_gene_id: Q9USZ6
symbol: mrt4
gene_biotype: protein_coding
description:
  Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.


ensembl_gene_id: Q9USZ7
symbol: end3
gene_biotype: protein_coding
description:
  Actin cytoskeleton-regulatory complex protein end3; Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).


ensembl_gene_id: Q9USZ8
symbol: fis1
gene_biotype: protein_coding
description:
  Mitochondrial fission 1 protein; Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity).


ensembl_gene_id: Q9UT03
symbol: sls1
gene_biotype: protein_coding
description:
  Protein sls1; Involved in aerobic respiration where it is required for assembly of respiratory chain enzyme complexes III and IV. Also has a role in mitochondrial gene expression (By similarity); Belongs to the SLS1 family.


ensembl_gene_id: Q9UT07
symbol: ups1
gene_biotype: protein_coding
description:
  Protein ups1 homolog; Required for maintenance of normal mitochondrial morphology as well as PCP1-dependent processing of MGM1.


ensembl_gene_id: Q9UT08
symbol: paa1
gene_biotype: protein_coding
description:
  Protein phosphatase PP2A regulatory subunit A; Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates (By similarity).


ensembl_gene_id: Q9UT09
symbol: SPAP8A3.07c
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP); Belongs to the class-I DAHP synthase family.


ensembl_gene_id: Q9UT16
symbol: atp12
gene_biotype: protein_coding
description:
  Protein atp12, mitochondrial; Essential for the assembly of the mitochondrial F1-F0 complex; Belongs to the ATP12 family.


ensembl_gene_id: Q9UT18
symbol: thi9
gene_biotype: protein_coding
description:
  Thiamine transporter thi9; Thiamine transporter involved in the cellular uptake of thiamine. Pyrithiamine, oxythiamine, amprolium, and the thiazole part of thiamine have been shown to be also substrates of thi9.


ensembl_gene_id: Q9UT19
symbol: met26
gene_biotype: protein_coding
description:
  Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: Q9UT21
symbol: SPAC9.07c
gene_biotype: protein_coding
description:
  Uncharacterized GTP-binding protein C9.07c; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: Q9UT22
symbol: SPAC9.06c
gene_biotype: protein_coding
description:
  Methylthioribulose-1-phosphate dehydratase-like protein; Belongs to the aldolase class II family. MtnB subfamily.


ensembl_gene_id: Q9UT23
symbol: fml1
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase fml1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinantion during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. FANCM-MHF also promotes non- crossover recombination in meiotic cells.


ensembl_gene_id: Q9UT24
symbol: brr2
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor brr2; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity). Required for pre- spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'- exon region.


ensembl_gene_id: Q9UT27
symbol: pvg1
gene_biotype: protein_coding
description:
  Pyruvyl transferase 1; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moieties to galactomannans and their subsequent pyruvylation.


ensembl_gene_id: Q9UT28
symbol: nnt1
gene_biotype: protein_coding
description:
  Protein N-terminal and lysine N-methyltransferase efm7; S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.


ensembl_gene_id: Q9UT30
symbol: brr6
gene_biotype: protein_coding
description:
  Nucleus export protein brr6; Involved in mRNA and protein export from nucleus. Belongs to the BRL1/BRR6 family.


ensembl_gene_id: Q9UT32
symbol: SPAC8F11.04
gene_biotype: protein_coding
description:
  Putative ribosome biogenesis protein C8F11.04; Involved in rRNA-processing and ribosome biosynthesis.


ensembl_gene_id: Q9UT33
symbol: dph3
gene_biotype: protein_coding
description:
  Diphthamide biosynthesis protein 3; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity). Belongs to the DPH3 family.


ensembl_gene_id: Q9UT35
symbol: gda1
gene_biotype: protein_coding
description:
  Guanosine-diphosphatase; After transfer of sugars to endogenous macromolecular acceptors, the enzyme converts nucleoside diphosphates to nucleoside monophosphates which in turn exit the Golgi lumen in a coupled antiporter reaction, allowing entry of additional nucleotide sugar from the cytosol; Belongs to the GDA1/CD39 NTPase family.


ensembl_gene_id: Q9UT36
symbol: glo2
gene_biotype: protein_coding
description:
  Probable hydroxyacylglutathione hydrolase C824.07; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: Q9UT37
symbol: tim14
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit tim14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (ssc1) (By similarity); Belongs to the TIM14 family.


ensembl_gene_id: Q9UT38
symbol: vps16
gene_biotype: protein_coding
description:
  Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology (By similarity).


ensembl_gene_id: Q9UT41
symbol: bst1
gene_biotype: protein_coding
description:
  GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.


ensembl_gene_id: Q9UT42
symbol: lsb6
gene_biotype: protein_coding
description:
  Phosphatidylinositol 4-kinase lsb6; May play a role in endocytic and/or exocytic pathways. Belongs to the PI3/PI4-kinase family.


ensembl_gene_id: Q9UT43
symbol: dnf1
gene_biotype: protein_coding
description:
  Putative phospholipid-transporting ATPase C821.13c; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.


ensembl_gene_id: Q9UT44
symbol: pro1
gene_biotype: protein_coding
description:
  Probable gamma-glutamyl phosphate reductase; Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity).


ensembl_gene_id: Q9UT45
symbol: eng1
gene_biotype: protein_coding
description:
  Endo-1,3(4)-beta-glucanase 1; Has a role in cell separation where it is required for the degradation of the primary septum after completion of cytokinesis.


ensembl_gene_id: Q9UT46
symbol: moc3
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein moc3; Induces sexual development and ascus formation. Also involved in calcium homeostasis.


ensembl_gene_id: Q9UT48
symbol: tif308
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.


ensembl_gene_id: Q9UT51
symbol: csn3
gene_biotype: protein_coding
description:
  COP9 signalosome complex subunit 3; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin- protein ligase complexes.


ensembl_gene_id: Q9UT52
symbol: mod21
gene_biotype: protein_coding
description:
  Gamma-tubulin complex subunit mod21; Component of the gamma-tubulin complex that is required for the regulation of both interphase microtubule organization and nucleation, and mitotic bipolar spindles. Required for correct septation.


ensembl_gene_id: Q9UT53
symbol: SPAC806.06c
gene_biotype: protein_coding
description:
  Nicotinamide/nicotinic acid mononucleotide adenylyltransferase; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate to form deamido- NAD(+) (NaAD). Key enzyme in both de novo and salvage pathways for NAD(+) biosynthesis.


ensembl_gene_id: Q9UT55
symbol: duf8901
gene_biotype: protein_coding
description:
  Damage-control phosphatase SPAC806.04c; Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (By similarity). Its preference for fructose-1- phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (By similarity).


ensembl_gene_id: Q9UT57
symbol: SPAC806.02c
gene_biotype: protein_coding
description:
  Probable cytosolic Fe-S cluster assembly factor SPAC806.02c; Fusion protein of two essential components of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. May form a heterotetramer with nubp35, functioning as a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (By similarity); In the C-terminal section; belongs to the WD repeat CIA1 family.


ensembl_gene_id: Q9UT60
symbol: dhd1
gene_biotype: protein_coding
description:
  Probable D-xylose 1-dehydrogenase (NADP(+)); NADP-dependent D-xylose dehydrogenase catalyzing the oxydation of D-xylose into D-xylonolactone (By similarity). May also display activity with other sugars. May play a role in the regeneration of NADP(+) in the presence of these sugars (Probable).


ensembl_gene_id: Q9UT61
symbol: ams1
gene_biotype: protein_coding
description:
  Alpha-mannosidase; Degrades free oligosaccharides in the vacuole; Belongs to the glycosyl hydrolase 38 family.


ensembl_gene_id: Q9UT67
symbol: imt2
gene_biotype: protein_coding
description:
  Inositol phosphoceramide mannosyltransferase 2; With imt1 and imt3, is required for the synthesis of mannosyl phosphorylinositol ceramide (MIPC). Catalyzes the addition of mannosyl to phosphorylinositol ceramide (IPC). MIPC is essential for cell morphology, cell-surface distribution of ergosterol, localization for plasma-membrane transporters, and lipid-raft-mediated endocytosis of plasma membrane proteins to the vacuole; Belongs to the glycosyltransferase 32 family.


ensembl_gene_id: Q9UT70
symbol: bet5
gene_biotype: protein_coding
description:
  Transport protein particle subunit bet5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.


ensembl_gene_id: Q9UT72
symbol: rfp2
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp2; Mediates ubiquitination and subsequent desumoylation/degradation of sumoylated proteins and proteins containing SUMO-like domains. Involved in maintaining genome stability where it acts in the cellular response to DNA damage.


ensembl_gene_id: Q9UT74
symbol: lys2
gene_biotype: protein_coding
description:
  Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.


ensembl_gene_id: Q9UT75
symbol: tit1
gene_biotype: protein_coding
description:
  tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).


ensembl_gene_id: Q9UT76
symbol: tif222
gene_biotype: protein_coding
description:
  Probable translation initiation factor eIF-2B subunit beta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B alpha/beta/delta subunits family.


ensembl_gene_id: Q9UT77
symbol: gta2
gene_biotype: protein_coding
description:
  Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).


ensembl_gene_id: Q9UT79
symbol: msc1
gene_biotype: protein_coding
description:
  Multicopy suppressor of chk1 protein 1; Has a role in regulating chromatin structure via global deacetylation of histone H3. This function is associated with the activity of a histone deacetylase.


ensembl_gene_id: Q9UT81
symbol: ubx3
gene_biotype: protein_coding
description:
  UBX domain-containing protein 3; Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Involved in delivery of substrates to the 26S proteasome. Also required for membrane fusion and sporulation.


ensembl_gene_id: Q9UT86
symbol: apc11
gene_biotype: protein_coding
description:
  Anaphase-promoting complex subunit 11; Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.


ensembl_gene_id: Q9UT91
symbol: rmp1
gene_biotype: protein_coding
description:
  Ribonuclease MRP protein subunit rmp1; Functions as part of ribonuclease MRP (RNase MRP), which is involved in rRNA processing in mitochondria.


ensembl_gene_id: Q9UT93
symbol: uba5
gene_biotype: protein_coding
description:
  NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric uba3-ula1 E1 enzyme. E1 activates NEDD8/ubl1 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of ubc12 (By similarity).


ensembl_gene_id: Q9UT94
symbol: mtq2
gene_biotype: protein_coding
description:
  eRF1 methyltransferase catalytic subunit mtq2; Methylates eRF1 on 'Gln-182' using S-adenosyl L-methionine as methyl donor. eRF1 needs to be complexed to eRF3 in its GTP-bound form to be efficiently methylated; Belongs to the eukaryotic/archaeal PrmC-related family.


ensembl_gene_id: Q9UT97
symbol: pup2
gene_biotype: protein_coding
description:
  Probable proteasome subunit alpha type-5; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1A family.


ensembl_gene_id: Q9UT98
symbol: pos5
gene_biotype: protein_coding
description:
  NADH kinase pos5, mitochondrial; Phosphorylates both NADH and NAD(+), with a preference for NADH. Anti-oxidant factor and key source of the cellular reductant NADPH (By similarity).


ensembl_gene_id: Q9UTA2
symbol: SPAC25B8.18
gene_biotype: protein_coding
description:
  Putative redox protein fmp46, mitochondrial; Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules; Belongs to the FMP46 family.


ensembl_gene_id: Q9UTA4
symbol: pop100
gene_biotype: protein_coding
description:
  Ribonucleases P/MRP protein subunit pop1; Required for processing of 5.8S rRNA (short form) at site A3 and for 5' and 3' processing of pre-tRNA; Belongs to the POP1 family.


ensembl_gene_id: Q9UTA5
symbol: tyw3
gene_biotype: protein_coding
description:
  tRNA wybutosine-synthesizing protein 3; S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 (By similarity).


ensembl_gene_id: Q9UTA8
symbol: SPAC25B8.10
gene_biotype: protein_coding
description:
  Uncharacterized methyltransferase-like C25B8.10; Probable methyltransferase; Belongs to the methyltransferase superfamily.


ensembl_gene_id: Q9UTA9
symbol: SPAC25B8.09
gene_biotype: protein_coding
description:
  Uncharacterized methyltransferase C25B8.09; Probable methyltransferase; Belongs to the methyltransferase superfamily.


ensembl_gene_id: Q9UTB2
symbol: dia4
gene_biotype: protein_coding
description:
  Serine--tRNA ligase, mitochondrial; Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).


ensembl_gene_id: Q9UTB3
symbol: deg1
gene_biotype: protein_coding
description:
  Putative tRNA pseudouridine synthase C25B8.05; Belongs to the tRNA pseudouridine synthase TruA family.


ensembl_gene_id: Q9UTB4
symbol: mss51
gene_biotype: protein_coding
description:
  Protein mss51; Has a dual role in the assembly of cytochrome oxidase subunit 1 (cox1). It has a regulative function on cox1 synthesis, acting as a translational activator specific for the cox1 mRNA, and it also binds to newly synthesized cox1 protein (By similarity); Belongs to the MSS51 family.


ensembl_gene_id: Q9UTB5
symbol: psd2
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme 2, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity). Together with psd1 and psd3, responsible for the majority of phosphatidylethanolamine synthesis. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.


ensembl_gene_id: Q9UTB6
symbol: sds3
gene_biotype: protein_coding
description:
  Transcriptional regulatory protein sds3; Component of the clr6 histone deacetylase complex I responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.


ensembl_gene_id: Q9UTC3
symbol: psf3
gene_biotype: protein_coding
description:
  DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication.


ensembl_gene_id: Q9UTC6
symbol: isu1
gene_biotype: protein_coding
description:
  Iron sulfur cluster assembly protein 1, mitochondrial; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. First, a [2Fe-2S] cluster is transiently assembled on the scaffold protein isu1. In a second step, the cluster is released from isu1, transferred to a glutaredoxin, followed by the formation of mitochondrial [2Fe-2S] proteins, the synthesis of [4Fe-4S] clusters and their target-specific insertion into the recipient apoproteins. Cluster a [...]


ensembl_gene_id: Q9UTC8
symbol: yos9
gene_biotype: protein_coding
description:
  Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity).


ensembl_gene_id: Q9UTC9
symbol: pfd2
gene_biotype: protein_coding
description:
  Probable prefoldin subunit 2; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity); Belongs to the prefoldin subunit beta family.


ensembl_gene_id: Q9UTD0
symbol: fol3
gene_biotype: protein_coding
description:
  Probable dihydrofolate synthetase; Glutamate-adding enzyme which catalyzes the binding of the first glutamyl side chain to dihydropteroate. Leads to the de nove synthesis of tetrahydrofolate. de novo (By similarity).


ensembl_gene_id: Q9UTD1
symbol: yth1
gene_biotype: protein_coding
description:
  mRNA 3'-end-processing protein yth1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the CPSF4/YTH1 family.


ensembl_gene_id: Q9UTD3
symbol: yip5
gene_biotype: protein_coding
description:
  Protein YIP5; Possible role in vesicle-mediated transport. May be involved in proper membrane localization of Rab GTPases (By similarity).


ensembl_gene_id: Q9UTD4
symbol: pfd4
gene_biotype: protein_coding
description:
  Probable prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity); Belongs to the prefoldin subunit beta family.


ensembl_gene_id: Q9UTD5
symbol: atg10
gene_biotype: protein_coding
description:
  Ubiquitin-like-conjugating enzyme ATG10; E2-like enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy and nucleophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for proper localization of ATG8 to the preautophagosomal structure (PAS). Likely serves as an ATG5-recognition molecule.


ensembl_gene_id: Q9UTD7
symbol: rrp15
gene_biotype: protein_coding
description:
  Ribosomal RNA-processing protein 15; Constituent of pre-60S ribosomal particles. Required for large subunit rRNA maturation (By similarity); Belongs to the RRP15 family.


ensembl_gene_id: Q9UTD8
symbol: erd1
gene_biotype: protein_coding
description:
  Protein ERD1 homolog 1; Required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus. Belongs to the ERD1 family.


ensembl_gene_id: Q9UTE0
symbol: sey1
gene_biotype: protein_coding
description:
  Protein sey1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.


ensembl_gene_id: Q9UTE2
symbol: hem13
gene_biotype: protein_coding
description:
  Probable oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX (By similarity).


ensembl_gene_id: Q9UTE5
symbol: hri2
gene_biotype: protein_coding
description:
  Eukaryotic translation initiation factor 2-alpha kinase 2; Mediates down-regulation of protein synthesis in response to stress conditions by the phosphorylation of the alpha subunit of eIF-2 (tif211) on 'Ser-52'. Protein synthesis is inhibited at the level of initiation. Activity is inhibited in the presence of heme. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.


ensembl_gene_id: Q9UTE7
symbol: mss1
gene_biotype: protein_coding
description:
  tRNA modification GTPase mss1, mitochondrial; GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: Q9UTE8
symbol: ies6
gene_biotype: protein_coding
description:
  Chromatin-remodeling complex subunit ies6; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Also involved in the regulation of telomere length (By similarity).


ensembl_gene_id: Q9UTE9
symbol: tim10
gene_biotype: protein_coding
description:
  Mitochondrial import inner membrane translocase subunit tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta- barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family.


ensembl_gene_id: Q9UTF6
symbol: cox6
gene_biotype: protein_coding
description:
  Cytochrome c oxidase subunit 6, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane  [...]


ensembl_gene_id: Q9UTF7
symbol: elo2
gene_biotype: protein_coding
description:
  Putative elongation of fatty acids protein 1; May be involved in the synthesis of very long chain fatty acids.


ensembl_gene_id: Q9UTF8
symbol: ugo1
gene_biotype: protein_coding
description:
  Mitochondrial fusion and transport protein ugo1; Required for mitochondrial fusion as well as normal mitochondrial morphology. May coordinate fusion of inner and outer membranes during mitochondrial fusion (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: Q9UTG1
symbol: SPAC1805.16c
gene_biotype: protein_coding
description:
  Putative purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine and inosine (By similarity).


ensembl_gene_id: Q9UTG2
symbol: pub2
gene_biotype: protein_coding
description:
  E3 ubiquitin-protein ligase pub2; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Has a role in the G2/M transition.


ensembl_gene_id: Q9UTG6
symbol: fmt1
gene_biotype: protein_coding
description:
  Putative methionyl-tRNA formyltransferase; Formylates methionyl-tRNA in mitochondria and the cytoplasm. Responsible for the formylation of the N-terminally formylated (Nt- formylated) mitochondrial matrix proteins that are encoded by mitochondrial DNA. Nt-formylated proteins in the cytoplasm are strongly up-regulated in stationary phase or upon starvation for specific amino acids and are targeted for degradation by an E3 ubiquitin ligase- mediated fMet/N-end rule pathway. Increased Nt-formylation of cytosolic proteins appears to be important for adaptation to these stresses.


ensembl_gene_id: Q9UTG8
symbol: dad2
gene_biotype: protein_coding
description:
  DASH complex subunit dad2; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore. May be necessary for growth under high osmotic stress.


ensembl_gene_id: Q9UTH0
symbol: nup132
gene_biotype: protein_coding
description:
  Nucleoporin nup132; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.


ensembl_gene_id: Q9UTH1
symbol: trm13
gene_biotype: protein_coding
description:
  tRNA:m(4)X modification enzyme TRM13; tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).


ensembl_gene_id: Q9UTH2
symbol: etf2
gene_biotype: protein_coding
description:
  Probable electron transfer flavoprotein subunit beta; The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF- ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).


ensembl_gene_id: Q9UTH9
symbol: dus3
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.


ensembl_gene_id: Q9UTI1
symbol: fub1
gene_biotype: protein_coding
description:
  Silencing boundary-establishment protein FUB1-like protein; May play a role in the establishment of transcriptional silencing boundaries, preventing the propagation of heterochromatic silencing.


ensembl_gene_id: Q9UTI2
symbol: grx2
gene_biotype: protein_coding
description:
  Glutaredoxin-2; The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione reductase. Thioltransferase catalyzes cellular thiol-disulfide transhydrogenation reactions. It transfers reducing equivalents to cytosolic protein and nonprotein disulfides (By similarity).


ensembl_gene_id: Q9UTI3
symbol: naa10
gene_biotype: protein_coding
description:
  N-terminal acetyltransferase A complex catalytic subunit ard1; Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover; Belongs to the acetyltransferase family. ARD1 subfamily.


ensembl_gene_id: Q9UTI4
symbol: moa1
gene_biotype: protein_coding
description:
  Monopolar attachment protein 1; Plays an important role in chromosome segregation during meiosis I by allowing meiotic rec8 to establish cohesion at the centromeric central core and thereby promote the side-by-side structure of kinetochores at meiosis I. Enables monopolar attachment during meiosis I. Required to facilitate kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Acts in collaboration with plo1.


ensembl_gene_id: Q9UTI5
symbol: vps29
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 29; Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor pep1/vps10. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The vps29- vps26-vps35 subcomplex may be involved in cargo selection.


ensembl_gene_id: Q9UTI7
symbol: hal3
gene_biotype: protein_coding
description:
  Probable thymidylate synthase; Required for both nuclear and mitochondrial DNA synthesis. In the N-terminal section; belongs to the HFCD (homo- oligomeric flavin containing Cys decarboxylase) superfamily.


ensembl_gene_id: Q9UTJ2
symbol: pmm1
gene_biotype: protein_coding
description:
  Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.


ensembl_gene_id: Q9UTJ4
symbol: cgr1
gene_biotype: protein_coding
description:
  rRNA-processing protein cgr1; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit; Belongs to the CGR1 family.


ensembl_gene_id: Q9UTJ7
symbol: sdh1
gene_biotype: protein_coding
description:
  Probable succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Q9UTJ8
symbol: rad50
gene_biotype: protein_coding
description:
  DNA repair protein rad50; Involved in DNA double-strand break (DSB) repair. Involved in mating type switching and has a role in choosing the sister chromatid for recombinational repair. Also has a role in telomere length maintenance.


ensembl_gene_id: Q9UTK0
symbol: nob1
gene_biotype: protein_coding
description:
  20S-pre-rRNA D-site endonuclease nob1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm (By similarity).


ensembl_gene_id: Q9UTK1
symbol: cox16
gene_biotype: protein_coding
description:
  Cytochrome c oxidase assembly protein cox16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family.


ensembl_gene_id: Q9UTK3
symbol: npt1
gene_biotype: protein_coding
description:
  Probable nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.


ensembl_gene_id: Q9UTK4
symbol: nup189
gene_biotype: protein_coding
description:
  Nucleoporin nup189; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. Nup189 is autocatalytically cleaved in vivo in 2 polypeptides which assume different function [...]


ensembl_gene_id: Q9UTK5
symbol: alm1
gene_biotype: protein_coding
description:
  Abnormal long morphology protein 1; After the onset of mitosis, at mid- to late anaphase, colocalizes with the medial actin ring. May play a role in cytokinesis.


ensembl_gene_id: Q9UTK7
symbol: dsc2
gene_biotype: protein_coding
description:
  DSC E3 ubiquitin ligase complex subunit 2; Component of the DSC E3 ubiquitin ligase complex which is required for the sre1 transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. The complex plays also an important role in the multivesicular body (MVB) pathway and functions in a post- endoplasmic reticulum pathway for protein degradation.


ensembl_gene_id: Q9UTK8
symbol: vrg4
gene_biotype: protein_coding
description:
  GDP-mannose transporter; Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.


ensembl_gene_id: Q9UTK9
symbol: SPAC144.17c
gene_biotype: protein_coding
description:
  Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase C144.17c; Synthesis and degradation of fructose 2,6-bisphosphate.


ensembl_gene_id: Q9UTL0
symbol: cia2
gene_biotype: protein_coding
description:
  MIP18 family protein C144.16; May play a role in chromosome segregation through establishment of sister chromatid cohesion.


ensembl_gene_id: Q9UTL1
symbol: cog1
gene_biotype: protein_coding
description:
  Conserved oligomeric Golgi complex subunit 1; Acts as essential component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra- Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).


ensembl_gene_id: Q9UTL4
symbol: gwt1
gene_biotype: protein_coding
description:
  GPI-anchored wall transfer protein 1; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor (By similarity). Has a role in meiosis.


ensembl_gene_id: Q9UTL5
symbol: sfc2
gene_biotype: protein_coding
description:
  Transcription factor IIIA; Is required for correct transcription of 5S RNA genes by RNA polymerase III. Also binds the transcribed 5S RNA's. Initiates transcription of the 5S ribosomal RNA gene.


ensembl_gene_id: Q9UTL6
symbol: jac1
gene_biotype: protein_coding
description:
  J-type co-chaperone jac1, mitochondrial; Co-chaperone required for the assembly of iron-sulfur (Fe/S) clusters in mitochondria. Stimulates the ATPase activity of the mitochondrial Hsp70 chaperone (mtHsp70). Binds to the substrate protein isu1 and targets it to mtHsp70 (By similarity); Belongs to the HscB family.


ensembl_gene_id: Q9UTL7
symbol: gpn2
gene_biotype: protein_coding
description:
  GPN-loop GTPase 2; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.


ensembl_gene_id: Q9UTL8
symbol: apl5
gene_biotype: protein_coding
description:
  AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity).


ensembl_gene_id: Q9UTM0
symbol: iec1
gene_biotype: protein_coding
description:
  INO80 complex subunit 1; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.


ensembl_gene_id: Q9UTM2
symbol: cox1101
gene_biotype: protein_coding
description:
  Cytochrome c oxidase assembly protein cox11-1; Rsm22-1 is involved in mitochondrion-encoded protein synthesis; In the C-terminal section; belongs to the COX11/CtaG family.


ensembl_gene_id: Q9UTM4
symbol: cct5
gene_biotype: protein_coding
description:
  T-complex protein 1 subunit epsilon; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).


ensembl_gene_id: Q9UTM7
symbol: hat1
gene_biotype: protein_coding
description:
  Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family.


ensembl_gene_id: Q9UTM8
symbol: SPAC139.05
gene_biotype: protein_coding
description:
  Putative succinate-semialdehyde dehydrogenase C139.05 [NADP(+)]; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Q9UTN1
symbol: oac1
gene_biotype: protein_coding
description:
  Mitochondrial oxaloacetate transport protein; Transports oxaloacetate and sulfate; Belongs to the mitochondrial carrier (TC 2.A.29) family.


ensembl_gene_id: Q9UTN3
symbol: cid14
gene_biotype: protein_coding
description:
  Poly(A) RNA polymerase cid14; Required for 3' polyadenylation of the 5.8S and 25S rRNAs as a prelude to their degradation in the exosome. Involved in the nucleolar organization to ensure faithful chromosome segregation during mitosis.


ensembl_gene_id: Q9UTN4
symbol: pfs2
gene_biotype: protein_coding
description:
  Polyadenylation factor subunit 2; Required for 3'-end cleavage and polyadenylation of pre- mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.


ensembl_gene_id: Q9UTN6
symbol: snf21
gene_biotype: protein_coding
description:
  Chromatin structure-remodeling complex subunit snf21; Helicase. Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.


ensembl_gene_id: Q9UTN8
symbol: ubc14
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 14; Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.


ensembl_gene_id: Q9UTN9
symbol: atl1
gene_biotype: protein_coding
description:
  Alkyltransferase-like protein 1; Involved in DNA damage recognition. Binds DNA containing O(6)-methylguanine and larger O(6)-alkylguanine adducts. The DNA is bent, the damaged base is rotated out of the DNA duplex into a hydrophobic binding pocket (nucleotide flipping), with Arg-39 donating a hydrogen bond to the orphaned cytosine to stabilize the extrahelical DNA conformation. This structural change in DNA presents the lesion to the nucleotide excision repair (NER) pathway. The affinity for O(6)-alkylguanine adducts increases with the size of the alkyl group. Low affinity small O(6)-a [...]


ensembl_gene_id: Q9UTP3
symbol: fta6
gene_biotype: protein_coding
description:
  Inner kinetochore subunit fta6; Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.


ensembl_gene_id: Q9UTP9
symbol: hca4
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase dbp4; ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).


ensembl_gene_id: Q9UTQ0
symbol: cca1
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase cca1; tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. In contrast to what is usually observed in eukaryotes for which one enzyme synthesizes the whole tRNA CCA terminus, in S.pombe, cca1 specifically adds two cytidine residues to a tRNA substrate lacking this sequence while cca2 specifically adds the terminal adenosine residue thereby completing the CCA sequence. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: Q9UTQ1
symbol: pdx3
gene_biotype: protein_coding
description:
  Probable pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: Q9UTQ7
symbol: arp9
gene_biotype: protein_coding
description:
  SWI/SNF and RSC complexes subunit arp9; Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes. Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing bindin [...]


ensembl_gene_id: Q9UTQ9
symbol: spc2
gene_biotype: protein_coding
description:
  Signal peptidase complex subunit spc2; Nonessential component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum. Spc2 enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).


ensembl_gene_id: Q9UTR1
symbol: mms19
gene_biotype: protein_coding
description:
  DNA repair/transcription protein mms19; Key component of the cytosolic iron-sulfur protein assembly (CIA) machinery that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. Acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as rad3/xpd and dna2, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription (By similarity).


ensembl_gene_id: Q9UTR5
symbol: rgf2
gene_biotype: protein_coding
description:
  Rho1 guanine nucleotide exchange factor 2; Stimulates the exchange of Rho1 and Rho5 GDP-bound form into GTP-bound form. Controls septum formation, cell wall synthesis and localization of F-actin patches.


ensembl_gene_id: Q9UTR6
symbol: och1
gene_biotype: protein_coding
description:
  Initiation-specific alpha-1,6-mannosyltransferase; Mannosyltransferase involved in outer chain elongation of asparagine-linked oligosaccharides of the type Man(9)GlcNAc(2). May otherwise add the first alpha-1,6-mannose to the Man(8)GlcNAc(2) core oligosaccharide from the ER. Represents the first enzymatic event required for synthesis of outer chain mannose linkages on yeast secretory proteins.


ensembl_gene_id: Q9UTR8
symbol: red1
gene_biotype: protein_coding
description:
  Protein red1; Required for elimination of meiosis-specific mRNAs from mitotic cells. Promotes the destabilization of mRNAs containing a degradation signal sequence called determinant of selective removal (DSR) to prevent ectopic expression of meiotic mRNAs in vegetative cells.


ensembl_gene_id: Q9UTR9
symbol: asa1
gene_biotype: protein_coding
description:
  ASTRA-associated protein 1; Component of the ASTRA complex probably involved in chromatin remodeling.


ensembl_gene_id: Q9UTT1
symbol: ubp15
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase 21; Involved in regulating the steady-state levels of proteins including prp4.


ensembl_gene_id: Q9UU76
symbol: puf6
gene_biotype: protein_coding
description:
  Pumilio homology domain family member 6; RNA-binding protein involved in post-transcriptional regulation; Belongs to the PUF6 family.


ensembl_gene_id: Q9UU78
symbol: rpp103
gene_biotype: protein_coding
description:
  60S acidic ribosomal protein P1-alpha 5; Plays an important role in the elongation step of protein synthesis; Belongs to the eukaryotic ribosomal protein P1/P2 family.


ensembl_gene_id: Q9UU79
symbol: nsa2
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein nsa2; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity).


ensembl_gene_id: Q9UU80
symbol: cwf18
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor cwf18; Involved in mRNA splicing where it associates with cdc5 and the other cwf proteins as part of the spliceosome.


ensembl_gene_id: Q9UU81
symbol: apl4
gene_biotype: protein_coding
description:
  AP-1 complex subunit gamma-1; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. The AP-1 complex interacts directly with clathrin (By similarity).


ensembl_gene_id: Q9UU83
symbol: pal1
gene_biotype: protein_coding
description:
  Protein pal1; Involved in cellular morphogenesis and cell wall integrity. Important for the maintenance of a cylindrical cell shape.


ensembl_gene_id: Q9UU86
symbol: SPCC1827.07c
gene_biotype: protein_coding
description:
  Protein SYG1 homolog; May function in G-protein coupled signal transduction. Belongs to the SYG1 (TC 2.A.94) family.


ensembl_gene_id: Q9UU88
symbol: fap7
gene_biotype: protein_coding
description:
  Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.


ensembl_gene_id: Q9UU89
symbol: ham1
gene_biotype: protein_coding
description:
  Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: Q9UU90
symbol: pop5
gene_biotype: protein_coding
description:
  Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences (By similarity).


ensembl_gene_id: Q9UU91
symbol: yop1
gene_biotype: protein_coding
description:
  Protein yop1; Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator.


ensembl_gene_id: Q9UU93
symbol: cnb1
gene_biotype: protein_coding
description:
  Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity).


ensembl_gene_id: Q9UU94
symbol: epl1
gene_biotype: protein_coding
description:
  Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).


ensembl_gene_id: Q9UU96
symbol: grc3
gene_biotype: protein_coding
description:
  Polynucleotide 5'-hydroxyl-kinase grc3; Polynucleotide 5'-kinase required for both rRNA processing and heterochromatic gene silencing.


ensembl_gene_id: Q9UUA0
symbol: SPCC23B6.02c
gene_biotype: protein_coding
description:
  Shuttling pre-60S factor C23B6.02c; Pre-ribosomal factor involved in 60S ribosomal protein subunit export from the nucleus.


ensembl_gene_id: Q9UUA2
symbol: pfh1
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase pfh1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Involved in the maintenance of mitochondrial (mtDNA). Required for both repair of mitochondrial DNA and recognition of a recombinogenic signal characterized by a 26-bp palindromic at sequence in the ery region of mitochondrial DNA. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. Required for the completion of S-phase. Belongs to the helicase family. PIF1 subfamily.


ensembl_gene_id: Q9UUA4
symbol: sec66
gene_biotype: protein_coding
description:
  Translocation protein sec66; Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and bip1 in a channel-forming translocon complex. A cycle of assembly and disassembly of Sec62/63 complex from sec61 may govern the activity of the translocon. sec66 is required to attach or retain sec72 in the sec63 complex (By similarity).


ensembl_gene_id: Q9UUA5
symbol: mtx1
gene_biotype: protein_coding
description:
  Metaxin-like protein C409.19c; May be involved in transport of proteins into the mitochondrion; Belongs to the metaxin family.


ensembl_gene_id: Q9UUA6
symbol: SPBC409.18
gene_biotype: protein_coding
description:
  Probable diacylglycerol pyrophosphate phosphatase 1; Catalyzes the dephosphorylation of diacylglycerol phosphate (DGPP) to phosphatidate (PA) and the subsequent dephosphorylation of PA to diacylglycerol (DAG); Belongs to the PA-phosphatase related phosphoesterase family.


ensembl_gene_id: Q9UUB1
symbol: rib4
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. Also binds riboflavin with an unexpected high affinity.


ensembl_gene_id: Q9UUB5
symbol: mis13
gene_biotype: protein_coding
description:
  Kinetochore protein mis13; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Required for correct segregation of chromosomes and for maintaining the inner centromere structure.


ensembl_gene_id: Q9UUB6
symbol: uch2
gene_biotype: protein_coding
description:
  Ubiquitin carboxyl-terminal hydrolase 2; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Belongs to the peptidase C12 family.


ensembl_gene_id: Q9UUB7
symbol: swi5
gene_biotype: protein_coding
description:
  Mating-type switching protein swi5; Required for normal mating-type switching. Also involved in the rhp51-dependent recombination DNA repair pathway.


ensembl_gene_id: Q9UUC6
symbol: smd3
gene_biotype: protein_coding
description:
  Small nuclear ribonucleoprotein Sm D3; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site (By similarity).


ensembl_gene_id: Q9UUC7
symbol: ctu2
gene_biotype: protein_coding
description:
  Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with ctu1 that ligates sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. Belongs to the CTU2/NCS2 family.


ensembl_gene_id: Q9UUC8
symbol: mrpl51
gene_biotype: protein_coding
description:
  54S ribosomal protein L51, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL43 family.


ensembl_gene_id: Q9UUC9
symbol: mdm34
gene_biotype: protein_coding
description:
  Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.


ensembl_gene_id: Q9UUD1
symbol: sre1
gene_biotype: protein_coding
description:
  Processed sterol regulatory element-binding protein 1; Transcriptional activator required for transcription of genes required for adaptation to anaerobic growth like those implicated in the nonrespiratory oxygen-consumptive biosynthetic pathways of sterol, heme, sphingolipid, and ubiquinone biosynthesis. May monitor oxygen levels through sterol synthesis steps which require oxygen.


ensembl_gene_id: Q9UUD2
symbol: prp38
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor 38; Required for pre-mRNA splicing and maintenance of stable U6 small nuclear RNA levels. Implicated in the formation of stable and biologically active snRNP structures. As part of the U4/U6.U5 tri-snRNP particle, dispensible for spliceosome assembly, but required for conformational changes, which result in U4 snRNA release and the subsequent catalytic activation of the spliceosome (By similarity).


ensembl_gene_id: Q9UUE1
symbol: pyr1
gene_biotype: protein_coding
description:
  Pyruvate carboxylase; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.


ensembl_gene_id: Q9UUE4
symbol: rct1
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase cyp6; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.


ensembl_gene_id: Q9UUE5
symbol: nup85
gene_biotype: protein_coding
description:
  Nucleoporin nup85; Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.


ensembl_gene_id: Q9UUE7
symbol: cdc73
gene_biotype: protein_coding
description:
  Cell division control protein 73; The PAF1 complex is a multifunctional complex. Involved in transcription initiation via genetic interactions with TATA-binding proteins. Involved in elongation. It regulates 3'-end formation of snR47 by modulating the recruitment or stable association of nrd1 with RNA polymerase II (By similarity).


ensembl_gene_id: Q9UUF0
symbol: pas4
gene_biotype: protein_coding
description:
  Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes. Belongs to the pex2/pex10/pex12 family.


ensembl_gene_id: Q9UUF1
symbol: SPBC17A3.08
gene_biotype: protein_coding
description:
  Deoxyribonuclease Tat-D; Has both endo- and exonuclease activities. Incises double- stranded DNA without obvious specificity via its endonuclease activity and excises the DNA from the 3'-to 5'-end by its exonuclease activity. May have a role in apoptosis (By similarity).


ensembl_gene_id: Q9UUF2
symbol: rar1
gene_biotype: protein_coding
description:
  Probable methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Q9UUF3
symbol: SPBC17A3.03c
gene_biotype: protein_coding
description:
  Probable tyrosine-protein phosphatase C17A3.03c; Belongs to the protein-tyrosine phosphatase family.


ensembl_gene_id: Q9UUF7
symbol: sec26
gene_biotype: protein_coding
description:
  Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).


ensembl_gene_id: Q9UUG0
symbol: fas1
gene_biotype: protein_coding
description:
  3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl- [acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier- protein] dehydratase.


ensembl_gene_id: Q9UUG3
symbol: dph4
gene_biotype: protein_coding
description:
  Diphthamide biosynthesis protein 4; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity). Belongs to the DPH4 family.


ensembl_gene_id: Q9UUG9
symbol: tsc2
gene_biotype: protein_coding
description:
  Tuberous sclerosis 2 protein homolog; Together with tsc1, required for uptake of various amino acids from the environment and for proper conjugation. Involved in induction of gene expression of permeases and genes required for meiosis upon nitrogen starvation. May act as a GTPase-activating protein (GAP) for the small GTPase rhb1.


ensembl_gene_id: Q9UUH1
symbol: vps55
gene_biotype: protein_coding
description:
  Vacuolar protein sorting-associated protein 55; Involved in protein transport from endosomes to the vacuole. Belongs to the OB-RGRP/VPS55 family.


ensembl_gene_id: Q9UUH2
symbol: bmt2
gene_biotype: protein_coding
description:
  25S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family.


ensembl_gene_id: Q9UUH4
symbol: erg25
gene_biotype: protein_coding
description:
  Methylsterol monooxygenase; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family.


ensembl_gene_id: Q9UUI1
symbol: lsm6
gene_biotype: protein_coding
description:
  U6 snRNA-associated Sm-like protein LSm6; Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2- LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6  [...]


ensembl_gene_id: Q9UUI2
symbol: shf1
gene_biotype: protein_coding
description:
  Small histone ubiquitination factor 1; Component of the histone H2B ubiquitin ligase complex (HULC) which plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.


ensembl_gene_id: Q9UUI3
symbol: sap145
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing factor sap145; Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity).


ensembl_gene_id: Q9UUI4
symbol: rrp16
gene_biotype: protein_coding
description:
  Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.


ensembl_gene_id: Q9UUI5
symbol: sec24
gene_biotype: protein_coding
description:
  Protein transport protein sec24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).


ensembl_gene_id: Q9UUI6
symbol: rtf1
gene_biotype: protein_coding
description:
  Replication termination factor 1; Mediates site-specific replication termination at the polar replication barrier RTS1, a barrier which ensures that replication of the mat1 locus in S.pombe occurs in the centromere-proximal direction.


ensembl_gene_id: Q9UUJ0
symbol: pvg5
gene_biotype: protein_coding
description:
  Pyruvylated Gal-beta-1,3-epitope synthesis protein 5; Involved in cell wall biogenesis. Has a role in the addition of Gal-beta1,3 moeities to galactomannans and their subsequent pyruvylation. Has a role in meiosis.


ensembl_gene_id: Q9UUJ1
symbol: arp2
gene_biotype: protein_coding
description:
  Actin-related protein 2; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity). During cytokinesis it colocalizes to the cortical actin patches until spetation is complete. Has a role in the mobility of these patches. Essential for viability.


ensembl_gene_id: Q9UUJ4
symbol: rec24
gene_biotype: protein_coding
description:
  Meiotic recombination protein rec24; Required for correct meiotic chromosome segregation and recombination.


ensembl_gene_id: Q9UUJ5
symbol: mrpl25
gene_biotype: protein_coding
description:
  54S ribosomal protein L25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL59 family.


ensembl_gene_id: Q9UUJ6
symbol: ned1
gene_biotype: protein_coding
description:
  Nuclear elongation and deformation protein 1; May have a role in the maintenance of the nuclear envelope structure and in minichromosome stability. Belongs to the lipin family.


ensembl_gene_id: Q9UUJ7
symbol: csn71
gene_biotype: protein_coding
description:
  COP9 signalosome complex subunit 7; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin- protein ligase complexes; Belongs to the CSN7/EIF3M family. CSN7 subfamily.


ensembl_gene_id: Q9UUJ9
symbol: ach1
gene_biotype: protein_coding
description:
  Acetyl-CoA hydrolase; Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.


ensembl_gene_id: Q9UUK0
symbol: SPAC1952.08c
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase C1952.08c homolog; Belongs to the pyridoxamine 5'-phosphate oxidase family.


ensembl_gene_id: Q9UUK1
symbol: SPAC1952.06c
gene_biotype: protein_coding
description:
  Beta-catenin-like protein 1 homolog; Probable spliceosomal component involved in the activation of pre-mRNA splicing.


ensembl_gene_id: Q9UUK2
symbol: gcn5
gene_biotype: protein_coding
description:
  Histone acetyltransferase gcn5; Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, and with a lower preference histone H4 to form H4K8ac and H4K16ac. Acetylation of histones gives a specific tag for epigenetic transcription activation (By similarity); Belongs to the acetyltransferase family. GCN5 subfamily.


ensembl_gene_id: Q9UUK3
symbol: otu2
gene_biotype: protein_coding
description:
  Ubiquitin thioesterase otu2; Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.


ensembl_gene_id: Q9UUL2
symbol: rad57
gene_biotype: protein_coding
description:
  DNA repair protein rhp57; Involved in recombination DNA repair and in the repair of gamma-ray-induced damage.


ensembl_gene_id: Q9UUM2
symbol: swi1
gene_biotype: protein_coding
description:
  Mating-type switching protein swi1; Forms a fork protection complex (FPC) with swi3. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. It is required for programmed fork-pausing which is necessary for mating-type switching. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors. It is involved in termination at the mat1-proximal polar- terminator of replication (RTS1) and also required for activation of the Rad53-like checkpoint kinase cds1.


ensembl_gene_id: Q9UUM7
symbol: hob3
gene_biotype: protein_coding
description:
  Protein hob3; Involved in cytokinesis and septation where it has a role in the localization of F-actin.


ensembl_gene_id: Q9Y6Z9
symbol: SPAC8E11.10
gene_biotype: protein_coding
description:
  Sorbose reductase sou1; Catalyzes the NADP dependent reduction of L-sorbose to D- glucitol; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Q9Y700
symbol: tuf1
gene_biotype: protein_coding
description:
  Elongation factor Tu, mitochondrial; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.


ensembl_gene_id: Q9Y703
symbol: alp31
gene_biotype: protein_coding
description:
  Tubulin-specific chaperone A; Required for the maintenance of microtubule structures and cell polarity. Beta-tubulin-folding protein; may have a regulatory role in the tubulin-folding pathway.


ensembl_gene_id: Q9Y705
symbol: alp4
gene_biotype: protein_coding
description:
  Spindle pole body component alp4; Component of the gamma tubule complex that is required for the regulation of both interphase microtubules and mitotic bipolar spindles. Required for correct septation; Belongs to the TUBGCP family.


ensembl_gene_id: Q9Y709
symbol: skp1
gene_biotype: protein_coding
description:
  Suppressor of kinetochore protein 1; Required for cig2 degradation in the G2 and M phases of the cell cycle. Together with pof6, essential for septum processing and cell separation. Involved in mitotic progression, essential for the execution of anaphase B; required for coordinated structural alterations of mitotic spindles and segregation of nuclear membrane structures at anaphase. Involved in the DNA damage checkpoint pathway and maintenance of genome integrity. Component of the RAVE complex which is required for stable assembly of the vacuolar ATPase complex V- ATPase. Belongs to th [...]


ensembl_gene_id: Q9Y738
symbol: mis12
gene_biotype: protein_coding
description:
  Centromere protein mis12; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Required for correct segregation of chromosomes and for maintaining the inner centromere structure; Belongs to the mis12 family.


ensembl_gene_id: Q9Y794
symbol: orc4
gene_biotype: protein_coding
description:
  Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. ORC binds to multiple sites within the ars1 origin of DNA replication in an ATP-independent manner. This binding is mediated by the N-terminal A.T hook repeats of orc4.


ensembl_gene_id: Q9Y7I4
symbol: alg3
gene_biotype: protein_coding
description:
  Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol; Belongs to the glycosyltransferase 58 family.


ensembl_gene_id: Q9Y7I8
symbol: zuo1
gene_biotype: protein_coding
description:
  Zuotin; Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain (By similarity).


ensembl_gene_id: Q9Y7J1
symbol: spo6
gene_biotype: protein_coding
description:
  Sporulation-specific protein 6; May act as a kinase regulator. Essential for progression of meiosis II and sporulation.


ensembl_gene_id: Q9Y7J3
symbol: SPBC1778.07
gene_biotype: protein_coding
description:
  Carnosine N-methyltransferase; N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).


ensembl_gene_id: Q9Y7J4
symbol: arc3
gene_biotype: protein_coding
description:
  Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.


ensembl_gene_id: Q9Y7J6
symbol: pdk1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase ppk21; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.


ensembl_gene_id: Q9Y7J9
symbol: num1
gene_biotype: protein_coding
description:
  Meiotic coiled-coil protein 5; Involved in chromosome segregation. Facilitates nuclear oscillation during meiotic prophase I, the 'horsetail' phase, by acting as a dynein anchor. Essential for anchoring dhc1 to the cortex. Required for proper sliding of the microtubules along the cell cortex, which leads to the proper U-turn movement of the nucleus.


ensembl_gene_id: Q9Y7K2
symbol: tor2
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase tor2; Phosphatidylinositol 3-kinase homolog, component of TORC1, which regulates multiple cellular processes to control cell growth in response to environmental signals. TORC1 controls the switch between cell proliferation and differentiation by sensing nutrient availability. Nutrient limitation and environmental stress signals cause inactivation of TORC1. Active TORC1 positively controls cell growth and ribosome biogenesis by regulating ribosomal protein gene expression. In nutrient rich conditions, responsible for the phosphorylation of AGC S6 kinase ( [...]


ensembl_gene_id: Q9Y7K7
symbol: tvp23
gene_biotype: protein_coding
description:
  Golgi apparatus membrane protein tvp23; Golgi membrane protein involved in vesicular trafficking. Belongs to the TVP23 family.


ensembl_gene_id: Q9Y7K8
symbol: nus1
gene_biotype: protein_coding
description:
  Dehydrodolichyl diphosphate synthase complex subunit nus1; With SPAC4D7.04c, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER).


ensembl_gene_id: Q9Y7L0
symbol: sec22
gene_biotype: protein_coding
description:
  Protein transport protein sec22; Nonessential SNARE involved in targeting and fusion of ER- derived transport vesicles with the Golgi complex as well as Golgi- derived retrograde transport vesicles with the ER; Belongs to the synaptobrevin family.


ensembl_gene_id: Q9Y7L4
symbol: exo5
gene_biotype: protein_coding
description:
  Probable exonuclease V, mitochondrial; Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).


ensembl_gene_id: Q9Y7L6
symbol: aps2
gene_biotype: protein_coding
description:
  AP-2 complex subunit sigma; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (By similarity).


ensembl_gene_id: Q9Y7L7
symbol: gpi15
gene_biotype: protein_coding
description:
  Phosphatidylinositol N-acetylglucosaminyltransferase subunit gpi15; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis; Belongs to the PIGH family.


ensembl_gene_id: Q9Y7L8
symbol: rps001
gene_biotype: protein_coding
description:
  40S ribosomal protein S0-A; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.


ensembl_gene_id: Q9Y7M1
symbol: hac1
gene_biotype: protein_coding
description:
  Putative 2-hydroxyacyl-CoA lyase; Catalyzes a carbon-carbon cleavage reaction; cleaves a 2- hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde; Belongs to the TPP enzyme family.


ensembl_gene_id: Q9Y7M4
symbol: lsm3
gene_biotype: protein_coding
description:
  Probable U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.


ensembl_gene_id: Q9Y7M6
symbol: nop52
gene_biotype: protein_coding
description:
  Ribosomal RNA-processing protein 1 homolog; Required for 27S rRNA processing to 25S and 5.8S. Belongs to the RRP1 family.


ensembl_gene_id: Q9Y7M7
symbol: mdl1
gene_biotype: protein_coding
description:
  ATP-dependent permease MDL1, mitochondrial; Mediates export of peptides generated upon proteolysis of mitochondrial inner membrane proteins; Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.


ensembl_gene_id: Q9Y7N0
symbol: bdf1
gene_biotype: protein_coding
description:
  SWR1 complex bromodomain subunit bdf1; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.


ensembl_gene_id: Q9Y7N2
symbol: rox3
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: Q9Y7N3
symbol: grx3
gene_biotype: protein_coding
description:
  Monothiol glutaredoxin-3; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters (By similarity). Binds one iron-sulfur cluster per dimer. The iron-sulfur cluster is bound between subunits, and is complexed by a bound glutathione and a cysteine residue from each subunit (By similarity).


ensembl_gene_id: Q9Y7N7
symbol: nar1
gene_biotype: protein_coding
description:
  Cytosolic Fe-S cluster assembly factor NAR1 homolog; Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity); Belongs to the NARF family.


ensembl_gene_id: Q9Y7P0
symbol: rib5
gene_biotype: protein_coding
description:
  Riboflavin synthase; Catalyzes the dismutation of two molecules of 6,7-dimethyl-8- ribityllumazine, resulting in the formation of riboflavin and 5-amino- 6-(D-ribitylamino)uracil.


ensembl_gene_id: Q9Y7P1
symbol: ero12
gene_biotype: protein_coding
description:
  ERO1-like protein 2; Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly pdi1 isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on pdi1 to transfer oxidizing equivalent. Does not oxidize all pdi related proteins, suggesting that it can discriminate between pdi1 and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion o [...]


ensembl_gene_id: Q9Y7P2
symbol: SPCC1450.15
gene_biotype: protein_coding
description:
  Uncharacterized protein C1450.15; Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein. Required for the formation of complete GPI precursors CP1 and CP2 (By similarity).


ensembl_gene_id: Q9Y7P3
symbol: ptl1
gene_biotype: protein_coding
description:
  Probable triacylglycerol lipase C1450.16c; Releases specific fatty acids from neutral lipid triacylglycerols (TAG) thereby supplying fatty acids to a general acylation process.


ensembl_gene_id: Q9Y7Q1
symbol: lto1
gene_biotype: protein_coding
description:
  LTO1 family protein C191.08; The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation.


ensembl_gene_id: Q9Y7Q6
symbol: set7
gene_biotype: protein_coding
description:
  SET domain-containing protein 7; Belongs to the class V-like SAM-binding methyltransferase superfamily.


ensembl_gene_id: Q9Y7R3
symbol: cnd2
gene_biotype: protein_coding
description:
  Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. The condensin complex probably also plays a role during interphase in processes such as DNA repair. Belongs to the CND2 (condensin subunit 2) family.


ensembl_gene_id: Q9Y7R4
symbol: set1
gene_biotype: protein_coding
description:
  Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the Set1 complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Methylation promotes maintenance of active chromatin states at euchromatic chromosomal domains and is present throughout the cell cycle. Plays a role in telomere maintenance and DNA repair in an ATM kinase rad3-dependent pathway. Required for efficient telomeric and centromeric silencing; Belongs to the class V-like SAM-binding methyltransferase superfamily.


ensembl_gene_id: Q9Y7R7
symbol: SPCC306.07c
gene_biotype: protein_coding
description:
  Putative ribosome biogenesis protein C306.07c; Involved in rRNA-processing and ribosome biosynthesis.


ensembl_gene_id: Q9Y7S6
symbol: SPCC569.07
gene_biotype: protein_coding
description:
  Aromatic amino acid aminotransferase C569.07; Has aromatic amino acid transaminase activity. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Q9Y7S9
symbol: aah3
gene_biotype: protein_coding
description:
  Alpha-amylase 3; Has a role in cell wall biosynthesis where it is involved in maintaining cell wall strength and shape.


ensembl_gene_id: Q9Y7T3
symbol: thg1
gene_biotype: protein_coding
description:
  tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.


ensembl_gene_id: Q9Y7T4
symbol: atg1
gene_biotype: protein_coding
description:
  Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...]


ensembl_gene_id: Q9Y7T6
symbol: sec59
gene_biotype: protein_coding
description:
  Dolichol kinase sec59; Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. It is required for spore germination. Has an essential role in cellular metabolism (By similarity). Belongs to the polyprenol kinase family.


ensembl_gene_id: Q9Y7T7
symbol: prp28
gene_biotype: protein_coding
description:
  Pre-mRNA-splicing ATP-dependent RNA helicase prp28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).


ensembl_gene_id: Q9Y7T8
symbol: pup3
gene_biotype: protein_coding
description:
  Probable proteasome subunit beta type-3; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity); Belongs to the peptidase T1B family.


ensembl_gene_id: Q9Y7U1
symbol: sfk1
gene_biotype: protein_coding
description:
  Protein sfk1; May control the production of phosphatidylinositol 4- phosphate (PI4P); Belongs to the SFK1 family.


ensembl_gene_id: Q9Y7U3
symbol: gep4
gene_biotype: protein_coding
description:
  Probable phosphatidylglycerophosphatase, mitochondrial; Phosphatidylglycerophosphatase involved in the biosynthesis of cardiolipin (CL), a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes and which has important functions for cellular energy metabolism, mitochondrial dynamics and the initiation of apoptotic pathways; Belongs to the GEP4 family.


ensembl_gene_id: Q9Y7U4
symbol: nse3
gene_biotype: protein_coding
description:
  Non-structural maintenance of chromosome element 3; Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis.


ensembl_gene_id: Q9Y7U5
symbol: rgf3
gene_biotype: protein_coding
description:
  Rho1 guanine nucleotide exchange factor 3; Stimulates the exchange of Rho1 GDP-bound form into GTP-bound form. Regulates, via interaction and activation of Rho1, beta-1,3- glucan biosynthesis and cell wall integrity during septation. Involved in the regulation of contractile ring assembly.


ensembl_gene_id: Q9Y7U6
symbol: rgf1
gene_biotype: protein_coding
description:
  Rho1 guanine nucleotide exchange factor 1; Stimulates the exchange of Rho1 and Rho5 GDP-bound form into GTP-bound form. Controls septum formation, cell wall synthesis and localization of F-actin patches. Coordinates actin deposition with cell wall biosynthesis during bipolar growth.


ensembl_gene_id: Q9Y7U8
symbol: mrpl37
gene_biotype: protein_coding
description:
  54S ribosomal protein L37, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL54 family.


ensembl_gene_id: Q9Y7U9
symbol: cca2
gene_biotype: protein_coding
description:
  tRNA nucleotidyltransferase cca2; tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. In contrast to what is usually observed in eukaryotes for which one enzyme synthesizes the whole tRNA CCA terminus, in S.pombe, cca1 specifically adds two cytidine residues to a tRNA substrate lacking this sequence while cca2 specifically adds the terminal adenosine residue thereby completing the CCA sequence. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: Q9Y7V0
symbol: mug117
gene_biotype: protein_coding
description:
  Meiotically up-regulated gene 117 protein; Required for correct meiotic chromosome segregation. Appears to also have role in sporulation.


ensembl_gene_id: Q9Y7V2
symbol: bye1
gene_biotype: protein_coding
description:
  Transcription factor bye1; Negative regulator of transcription elongation. Belongs to the BYE1 family.


ensembl_gene_id: Q9Y7X2
symbol: nat1
gene_biotype: protein_coding
description:
  N-terminal acetyltransferase A complex subunit-like protein C418.02; Non-catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover (By similarity).


ensembl_gene_id: Q9Y7X5
symbol: uge1
gene_biotype: protein_coding
description:
  UDP-glucose 4-epimerase uge1; Major UDP-glucose/-galactose 4-epimerase under glucose-rich conditions involved in protein galactosylation.


ensembl_gene_id: Q9Y7X6
symbol: ish1
gene_biotype: protein_coding
description:
  Stress response protein ish1; Has a role in maintaining cell viability during stationary phase induced by stress response. Activated by the spc1 MAPK pathway. Belongs to the LEA type 1 family.


ensembl_gene_id: Q9Y7X8
symbol: arp5
gene_biotype: protein_coding
description:
  Actin-like protein arp5; Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.


ensembl_gene_id: Q9Y7Y4
symbol: cox10
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O.


ensembl_gene_id: Q9Y7Y5
symbol: rtt109
gene_biotype: protein_coding
description:
  Histone acetyltransferase rtt109; Required for acetylation of 'Lys-56' of histone H3 (H3K56ac), which occurs predominantly in newly synthesized H3 molecule during G1, S-phase and G2/M of cell cycle. Histone H3 'Lys-56' acetylation is required for S-phase-linked DNA damage tolerance and proper silencing in pericentromeric heterochromatin.


ensembl_gene_id: Q9Y7Y7
symbol: gas4
gene_biotype: protein_coding
description:
  1,3-beta-glucanosyltransferase gas4; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall. Involved in spore wall assembly.


ensembl_gene_id: Q9Y7Z2
symbol: arf6
gene_biotype: protein_coding
description:
  ADP-ribosylation factor 6; GTP-binding protein that functions as a molecular switch for the activation of 'new end take off' (NETO), a process in which the directions of cell growth change from a monopolar manner to a bipolar manner in fission yeast. Involved in supplying membrane to the growing new end; Belongs to the small GTPase superfamily. Arf family.


ensembl_gene_id: Q9Y7Z3
symbol: acb1
gene_biotype: protein_coding
description:
  Putative acyl-CoA-binding protein; Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters; Belongs to the ACBP family.


ensembl_gene_id: Q9Y7Z4
symbol: cog3
gene_biotype: protein_coding
description:
  Conserved oligomeric Golgi complex subunit 3; Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis- Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events (By similarity).


ensembl_gene_id: Q9Y7Z5
symbol: tts1
gene_biotype: protein_coding
description:
  Tetra-spanning protein 1; Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator.


ensembl_gene_id: Q9Y7Z7
symbol: mrp15
gene_biotype: protein_coding
description:
  54S ribosomal protein L15, mitochondrial; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL57 subfamily.


ensembl_gene_id: Q9Y7Z8
symbol: myo1
gene_biotype: protein_coding
description:
  Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Contributes to proper septation by transporting vesicles containing septal material to the division site and is involved in the formation of sterol-rich membrane domains at the cell division site. Required also for mating.


ensembl_gene_id: Q9Y7Z9
symbol: coq6
gene_biotype: protein_coding
description:
  Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6; Belongs to the UbiH/COQ6 family.


ensembl_gene_id: Q9Y800
symbol: mug97
gene_biotype: protein_coding
description:
  Meiotically up-regulated gene 97 protein; Required for correct meiotic chromosome segregation. Appears to also have role in sporulation.


ensembl_gene_id: Q9Y802
symbol: lsd1
gene_biotype: protein_coding
description:
  Lysine-specific histone demethylase 1; Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Has a role in regulating heterochromatin propagation and euchromatic transcription. Also has a gene activating role; Belongs to the flavin monoamine oxidase family.


ensembl_gene_id: Q9Y804
symbol: fan1
gene_biotype: protein_coding
description:
  Fanconi-associated nuclease 1 homolog; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions (By similarity).


ensembl_gene_id: Q9Y806
symbol: erv2
gene_biotype: protein_coding
description:
  FAD-linked sulfhydryl oxidase erv2; FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation in the endoplasmic reticulum lumen.


ensembl_gene_id: Q9Y808
symbol: med15
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Component of a med15-hrp [...]


ensembl_gene_id: Q9Y809
symbol: naa25
gene_biotype: protein_coding
description:
  N-terminal acetyltransferase B complex subunit arm1; Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met.


ensembl_gene_id: Q9Y810
symbol: shy1
gene_biotype: protein_coding
description:
  Cytochrome oxidase assembly protein shy1; Required for efficient assembly of cytochrome c oxidase in the mitochondrial inner membrane; Belongs to the SURF1 family.


ensembl_gene_id: Q9Y812
symbol: cnp1
gene_biotype: protein_coding
description:
  Histone H3-like centromeric protein cnp1; Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division.


ensembl_gene_id: Q9Y813
symbol: rpr2
gene_biotype: protein_coding
description:
  Ribonuclease P protein subunit rpr2; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 4 family.


ensembl_gene_id: Q9Y814
symbol: htd2
gene_biotype: protein_coding
description:
  Hydroxyacyl-thioester dehydratase type 2, mitochondrial; Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis. Required for respiratory growth and for normal mitochondrial morphology (By similarity); Belongs to the HTD2 family.


ensembl_gene_id: Q9Y817
symbol: rav1
gene_biotype: protein_coding
description:
  Regulator of V-ATPase in vacuolar membrane protein 1; Component of the RAVE complex which is required for stable assembly of the vacuolar ATPase complex V-ATPase.


ensembl_gene_id: Q9Y818
symbol: ubc15
gene_biotype: protein_coding
description:
  Ubiquitin-conjugating enzyme E2 15; Catalyzes the covalent attachment of ubiquitin to other proteins. Has a role in the formation of chromatin structures that influence the localization of transcriptional silencing factors.


ensembl_gene_id: Q9Y821
symbol: pmc4
gene_biotype: protein_coding
description:
  Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.


ensembl_gene_id: Q9Y823
symbol: lys4
gene_biotype: protein_coding
description:
  Homocitrate synthase, mitochondrial; Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.


ensembl_gene_id: Q9Y876
symbol: psh3
gene_biotype: protein_coding
description:
  Secretory component protein psh3; Involved in amino acid permease processing and required for the efficient translocation of structurally related amino acid permeases from the endoplasmic reticulum to the plasma membrane.


ensembl_gene_id: Q9Y884
symbol: pek1
gene_biotype: protein_coding
description:
  MAP kinase kinase skh1/pek1; Involved in the mkh1 signal transduction pathway that plays a role in cell wall integrity. Activates spm1/pmk1 via phosphorylation.


ensembl_gene_id: Q9Y8G3
symbol: mex67
gene_biotype: protein_coding
description:
  mRNA export factor mex67; Involved in the export of mRNA from the nucleus to the cytoplasm; Belongs to the NXF family.


ensembl_gene_id: U3H041
symbol: SPBPB21E7.02c
gene_biotype: protein_coding
description:
  Probable phosphatase SPBPB21E7.02c; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: U3H042
symbol: sos7
gene_biotype: protein_coding
description:
  Kinetochore protein Sos7; Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Essential for chromosome segregation and bipolar sister chromatid association. Required for kinetochore targeting of MIND, but not Ndc80 complex components.


