# geneInfo

ensembl_gene_id: PAU_00001
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: PAU_00002
symbol: dnaN
gene_biotype: protein_coding
description:
  DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of  [...]


ensembl_gene_id: PAU_00003
symbol: recF
gene_biotype: protein_coding
description:
  Dna replication and repair protein recf; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: PAU_00004
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PAU_00005
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: PAU_00033
symbol: glmS
gene_biotype: protein_coding
description:
  L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: PAU_00034
symbol: glmU
gene_biotype: protein_coding
description:
  Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: PAU_00035
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: PAU_00036
symbol: atpD
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase F1 sector beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: PAU_00037
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: PAU_00038
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: PAU_00039
symbol: atpH
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase F1 sector delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: PAU_00040
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: PAU_00041
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase C chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: PAU_00042
symbol: atpB
gene_biotype: protein_coding
description:
  Membrane-bound ATP synthase F0 sector subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: PAU_00044
symbol: gidB
gene_biotype: protein_coding
description:
  Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: PAU_00045
symbol: gidA
gene_biotype: protein_coding
description:
  tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: PAU_00051
symbol: rbsD
gene_biotype: protein_coding
description:
  High affinity ribose transport protein rbsd; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.


ensembl_gene_id: PAU_00052
symbol: rbsA
gene_biotype: protein_coding
description:
  Ribose transport atp-binding protein rbsa; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: PAU_00053
symbol: rbsC
gene_biotype: protein_coding
description:
  Ribose transport system permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PAU_00055
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: PAU_00060
symbol: actP
gene_biotype: protein_coding
description:
  Cation/acetate symporter actp (acetate transporter actp) (acetat permease); Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PAU_00062
symbol: acs
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. A [...]


ensembl_gene_id: PAU_00063
symbol: sodA
gene_biotype: protein_coding
description:
  Superoxide dismutase [mn] (mnsod); Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: PAU_00066
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase (tryptophan--tRNA ligase (trprs); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PAU_00067
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: PAU_00071
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: PAU_00072
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: PAU_00077
symbol: mrcA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1a (pbp-1a) (pbp1a) (penicillin-bindin protein a); Penicillin-binding protein.


ensembl_gene_id: PAU_00082
symbol: hslO
gene_biotype: protein_coding
description:
  33 kda chaperonin (heat shock protein 33 homolog) (hsp33); Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: PAU_00083
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: PAU_00091
symbol: pulA
gene_biotype: protein_coding
description:
  Alpha-dextrin endo-1,6-alpha-glucosidase (pullulanase); Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: PAU_00092
symbol: cynS
gene_biotype: protein_coding
description:
  Cyanate hydratase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.


ensembl_gene_id: PAU_00105
symbol: uspA
gene_biotype: protein_coding
description:
  The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general stress endurance activity.


ensembl_gene_id: PAU_00106
symbol: gdhA
gene_biotype: protein_coding
description:
  Nadp-specific glutamate dehydrogenase (nadp-gdh); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: PAU_00125
symbol: uxuB
gene_biotype: protein_coding
description:
  Mannonate oxidoreductase (d-mannonate oxidoreductase); Belongs to the mannitol dehydrogenase family.


ensembl_gene_id: PAU_00127
symbol: kdgK
gene_biotype: protein_coding
description:
  2-dehydro-3-deoxygluconokinase (2-keto-3-deoxygluconokinase) (3-deoxy 2-oxo-d-gluconate kinase) (kdg kinase).


ensembl_gene_id: PAU_00133
symbol: glpD
gene_biotype: protein_coding
description:
  Aerobic glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PAU_00136
symbol: glpE
gene_biotype: protein_coding
description:
  Thiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: PAU_00137
symbol: gntY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: PAU_00140
symbol: tyrS2
gene_biotype: protein_coding
description:
  Tyrosyl-trna synthetase 2; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: PAU_00141
symbol: spnH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Probable o-methyltransferase; similarities with putative methyltransferase.


ensembl_gene_id: PAU_00146
symbol: ydeF
gene_biotype: protein_coding
description:
  Putative membrane transport protein; MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients.


ensembl_gene_id: PAU_00148
symbol: bioH
gene_biotype: protein_coding
description:
  Carboxylesterase BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: PAU_00150
symbol: yhgG
gene_biotype: protein_coding
description:
  Similar to putative DNA-binding transcriptional regulator protein yhgg of escherichia coli; May function as a transcriptional regulator that controls feoABC expression.


ensembl_gene_id: PAU_00151
symbol: feoB
gene_biotype: protein_coding
description:
  Ferrous iron transport protein b; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: PAU_00152
symbol: feoA
gene_biotype: protein_coding
description:
  iron(II) transport system (feo) which may make an important contribution to the iron supply of the cell under anaerobic conditions.


ensembl_gene_id: PAU_00155
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor greb (transcript cleavage facto greb); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: PAU_00159
symbol: PAU_00159
gene_biotype: protein_coding
description:
  Similarities with MFS transporter protein; MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients.


ensembl_gene_id: PAU_00162
symbol: pstS
gene_biotype: protein_coding
description:
  Phosphate-binding periplasmic protein psts; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: PAU_00163
symbol: pstC
gene_biotype: protein_coding
description:
  Phosphate transport system permease protein pstc; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PAU_00165
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate import ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: PAU_00166
symbol: phoU
gene_biotype: protein_coding
description:
  Phosphate transport system protein phou; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.


ensembl_gene_id: PAU_00167
symbol: fliY
gene_biotype: protein_coding
description:
  Putative periplasmic binding transport protein; Belongs to the bacterial solute-binding protein 3 family.


ensembl_gene_id: PAU_00174
symbol: yihI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: PAU_00175
symbol: hemN
gene_biotype: protein_coding
description:
  Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: PAU_00177
symbol: glnG
gene_biotype: protein_coding
description:
  Nitrogen regulation protein nr(i); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: PAU_00182
symbol: PAU_00182
gene_biotype: protein_coding
description:
  Carbon starvation protein CstA is a predicted membrane protein. It has been suggested that CstA is involved in peptide utilization.


ensembl_gene_id: PAU_00184
symbol: dtd
gene_biotype: protein_coding
description:
  d-tyrosyl-tRNA(tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: PAU_00191
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symport carrier protein (glutamate permease); Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: PAU_00196
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PAU_00199
symbol: aufB
gene_biotype: protein_coding
description:
  Similarities with putative fimbrial chaperone; Periplasmic chaperones assist pili assembly by binding to the subunits, thereby preventing premature aggregation.


ensembl_gene_id: PAU_00203
symbol: afaB
gene_biotype: protein_coding
description:
  Afab; Periplasmic chaperones assist pili assembly by binding to the subunits, thereby preventing premature aggregation; similar to pilli chaperone.


ensembl_gene_id: PAU_00204
symbol: agg3D
gene_biotype: protein_coding
description:
  Similar to putative fimbrial chaperone; Periplasmic chaperones assist pili assembly by binding to the subunits, thereby preventing premature aggregation.


ensembl_gene_id: PAU_00209
symbol: spoT
gene_biotype: protein_coding
description:
  Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: PAU_00210
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: PAU_00221
symbol: yicF
gene_biotype: protein_coding
description:
  Similar to putative dna ligase-like protein yicf of escherichia coli; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: PAU_00225
symbol: avtA
gene_biotype: protein_coding
description:
  Valine--pyruvate aminotransferase; Alanine-alpha-ketoisovalerate (or valine-pyruvate) transaminase transaminase c (valine-pyruvate transaminase).


ensembl_gene_id: PAU_00226
symbol: tag
gene_biotype: protein_coding
description:
  Dna-3-methyladenine glycosylase i (3-methyladenine-dna glycosylase i constitutive) (tag i) (dna-3-methyladenine glycosidase i).


ensembl_gene_id: PAU_00235
symbol: dppF
gene_biotype: protein_coding
description:
  Putative atp-binding component of dipeptide transport system; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PAU_00275
symbol: pmt1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; This entry represents a conserved region within several bacterial proteins that resemble ImcF, which has been proposed to be involved in cell surface reorganisation, resulting in increased adherence to epithelial cells and increased conjugation frequency.


ensembl_gene_id: PAU_00296
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein a; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: PAU_00297
symbol: rdoA
gene_biotype: protein_coding
description:
  Antibiotic resistance protein rdoa; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: PAU_00299
symbol: polA
gene_biotype: protein_coding
description:
  Dna polymerase I polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: PAU_00301
symbol: engB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: PAU_00302
symbol: ppiA
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase A precursor; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: PAU_00305
symbol: argD
gene_biotype: protein_coding
description:
  Acetylornithine/succinyldiaminopimelate aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: PAU_00315
symbol: yfeU
gene_biotype: protein_coding
description:
  Similar to putative regulator yfeu protein of escherichia coli; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.


ensembl_gene_id: PAU_00325
symbol: PAU_00325
gene_biotype: protein_coding
description:
  Similar to putative lysr-family trancsriptional regulator; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_00327
symbol: kefG
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system ancillary protein kefg; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.


ensembl_gene_id: PAU_00328
symbol: kefB
gene_biotype: protein_coding
description:
  Glutathione-regulated potassium-efflux system protein KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.


ensembl_gene_id: PAU_00336
symbol: tusD
gene_biotype: protein_coding
description:
  Sulfurtransferase tusd; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.


ensembl_gene_id: PAU_00337
symbol: tusC
gene_biotype: protein_coding
description:
  Protein tusc (trna 2-thiouridine synthesizing protein c); Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: PAU_00338
symbol: tusB
gene_biotype: protein_coding
description:
  Protein tusb (trna 2-thiouridine synthesizing protein b); Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: PAU_00339
symbol: rpsL
gene_biotype: protein_coding
description:
  30s ribosomal protein s12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: PAU_00340
symbol: rpsG
gene_biotype: protein_coding
description:
  30s ribosomal subunit protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: PAU_00341
symbol: fusA
gene_biotype: protein_coding
description:
  Elongation factor g (ef-g); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: PAU_00342
symbol: tufA
gene_biotype: protein_coding
description:
  Elongation factor tu-b (ef-tu-b); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: PAU_00344
symbol: secE
gene_biotype: protein_coding
description:
  Inner membrane preprotein translocase; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: PAU_00345
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Bel [...]


ensembl_gene_id: PAU_00346
symbol: rplK
gene_biotype: protein_coding
description:
  50s ribosomal protein l11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: PAU_00347
symbol: rplA
gene_biotype: protein_coding
description:
  50s ribosomal subunit protein l1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: PAU_00348
symbol: rplJ
gene_biotype: protein_coding
description:
  50s ribosomal subunit protein l10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: PAU_00349
symbol: rplL
gene_biotype: protein_coding
description:
  50s ribosomal subunit protein l7/l12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: PAU_00350
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PAU_00351
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PAU_00365
symbol: lamB
gene_biotype: protein_coding
description:
  Maltoporin precursor (maltose-inducible porin) (lambda recepto protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.


ensembl_gene_id: PAU_00366
symbol: malK
gene_biotype: protein_coding
description:
  Maltose/maltodextrin import ATP-binding protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.


ensembl_gene_id: PAU_00367
symbol: malE
gene_biotype: protein_coding
description:
  Maltose-binding periplasmic protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: PAU_00377
symbol: malP
gene_biotype: protein_coding
description:
  Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: PAU_00379
symbol: malT
gene_biotype: protein_coding
description:
  Hth-type transcriptional regulator malt (atp-dependent transcriptiona activator malt); Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.


ensembl_gene_id: PAU_00381
symbol: gabT
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase activity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PAU_00390
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis protein thig; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: PAU_00393
symbol: thiE
gene_biotype: protein_coding
description:
  Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: PAU_00394
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein thic; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: PAU_00400
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: PAU_00401
symbol: nfi
gene_biotype: protein_coding
description:
  Endonuclease V (deoxyinosine 3'endoduclease); DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: PAU_00403
symbol: dbhA
gene_biotype: protein_coding
description:
  Dna-binding protein hu-alpha (ns2) (hu-2); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: PAU_00409
symbol: metA
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: PAU_00418
symbol: aceK
gene_biotype: protein_coding
description:
  Isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: PAU_00425
symbol: PAU_00425
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Similarities with isobutylamine n-hydroxylase and putative oxidoreductase.


ensembl_gene_id: PAU_00442
symbol: pxpA
gene_biotype: protein_coding
description:
  Lamb/ycsf; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: PAU_00452
symbol: PAU_00452
gene_biotype: protein_coding
description:
  Hypothetical protein; Putative pyocin r2_pp, tail length determination protein; otthump00000017444 (fragment).


ensembl_gene_id: PAU_00453
symbol: bacA
gene_biotype: protein_coding
description:
  Similar to antibiotic synthetases - bacitracin synthetase 1 (ba1) [includes: atp-dependent isoleucin adenylase (ilea) (isoleucine activase); atp-dependent cystein adenylase (cysa) (cysteine activase); atp-dependent leucine adenylas (leua) (leucine activase); atp-dependent glutamate adenylase (glua (glutamate activase); atp-dependent isoleucine adenylase (ilea (isoleucine activase); glutamate racemase.


ensembl_gene_id: PAU_00454
symbol: PAU_00454
gene_biotype: protein_coding
description:
  Putative polyketide synthase; Nvolved in the biosynthesis of a polyketide antibiotic; polyketide antibiotic synthase enzyme systems.


ensembl_gene_id: PAU_00456
symbol: def1
gene_biotype: protein_coding
description:
  Peptide deformylase 2; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: PAU_00466
symbol: iunH
gene_biotype: protein_coding
description:
  Inosine-uridine preferring nucleoside hydrolase (iu-nucleosid hydrolase) (purine nucleosidase); Belongs to the IUNH family.


ensembl_gene_id: PAU_00487
symbol: rsmC
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase C; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: PAU_00488
symbol: holD
gene_biotype: protein_coding
description:
  DNA polymerase III, Psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.


ensembl_gene_id: PAU_00489
symbol: rimI
gene_biotype: protein_coding
description:
  Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: PAU_00490
symbol: prfC
gene_biotype: protein_coding
description:
  Peptide chain release factor 3 (rf-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: PAU_00494
symbol: yeiM
gene_biotype: protein_coding
description:
  Similar to hypothetical transport protein; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: PAU_00513
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: PAU_00514
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: PAU_00515
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: PAU_00521
symbol: radA
gene_biotype: protein_coding
description:
  Dna repair protein rada; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: PAU_00527
symbol: trpR
gene_biotype: protein_coding
description:
  Trp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.


ensembl_gene_id: PAU_00528
symbol: yjjX
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: PAU_00532
symbol: arcA
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, aerobic respiration control protein ArcA; Negative response regulator of genes in aerobic pathways, (sensors arcb and cpxa) (dye resistance protein).


ensembl_gene_id: PAU_00533
symbol: thrA
gene_biotype: protein_coding
description:
  Aspartokinase i-homoserine dehydrogenase i; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: PAU_00534
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: PAU_00538
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: PAU_00540
symbol: galT
gene_biotype: protein_coding
description:
  Galactose-1-phosphate uridylyltransferase (gal-1-uridylyltransferase) (udp-glucose--hexose-1-phosphat uridylyltransferase).


ensembl_gene_id: PAU_00541
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: PAU_00543
symbol: dnaK
gene_biotype: protein_coding
description:
  Chaperone hsp70, autoregulated heat shock protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.


ensembl_gene_id: PAU_00544
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone with dnak; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]


ensembl_gene_id: PAU_00551
symbol: nhaA
gene_biotype: protein_coding
description:
  Na(+)/h(+) antiporter 1 (sodium/proton antiporter 1); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: PAU_00555
symbol: ileS
gene_biotype: protein_coding
description:
  isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: PAU_00556
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: PAU_00559
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.


ensembl_gene_id: PAU_00560
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: PAU_00564
symbol: folA
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: PAU_00565
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'-nucleosyl)-tetraphosphatase, symmetrical; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: PAU_00567
symbol: ksgA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: PAU_00568
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: PAU_00569
symbol: surA
gene_biotype: protein_coding
description:
  Chaperone SurA precursor (peptidyl-prolyl cis-trans isomerase); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: PAU_00570
symbol: imp
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein precursor; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: PAU_00571
symbol: djlA
gene_biotype: protein_coding
description:
  Dnaj-like protein djla; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: PAU_00572
symbol: rluA
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PAU_00573
symbol: rapA
gene_biotype: protein_coding
description:
  Probable ATP-dependent RNA helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: PAU_00576
symbol: thiQ
gene_biotype: protein_coding
description:
  Thiamine import ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.


ensembl_gene_id: PAU_00579
symbol: rppH
gene_biotype: protein_coding
description:
  RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: PAU_00580
symbol: ptsP
gene_biotype: protein_coding
description:
  Phosphotransferase system, enzyme I, PtsP; Phosphoenolpyruvate-protein phosphotransferase pts (phosphotransferase system, enzyme i) (enzyme i-ntr); Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: PAU_00581
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: PAU_00582
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: PAU_00589
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease v gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]


ensembl_gene_id: PAU_00591
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...]


ensembl_gene_id: PAU_00592
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...]


ensembl_gene_id: PAU_00598
symbol: mltA
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase a (murein hydrolase a); Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: PAU_00604
symbol: ygdE
gene_biotype: protein_coding
description:
  Putative RNA 2'-O-ribose methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: PAU_00608
symbol: PAU_00608
gene_biotype: protein_coding
description:
  Alkaline protease secretion protein apre; Secretion of virulence factors in Gram-negative bacteria involves transportation of the protein across two membranes to reach the cell exterior.


ensembl_gene_id: PAU_00610
symbol: xni
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease ix-like protein; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: PAU_00612
symbol: queF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: PAU_00635
symbol: syd
gene_biotype: protein_coding
description:
  Putative membrane protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: PAU_00641
symbol: dapD
gene_biotype: protein_coding
description:
  2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: PAU_00642
symbol: glnD
gene_biotype: protein_coding
description:
  [protein-pII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: PAU_00643
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: PAU_00645
symbol: tsf
gene_biotype: protein_coding
description:
  Elongation factor ts (ef-ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: PAU_00647
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor (ribosome-releasing factor) (rrf); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: PAU_00648
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-d-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).


ensembl_gene_id: PAU_00649
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: PAU_00652
symbol: yaeT
gene_biotype: protein_coding
description:
  Outer membrane protein assembly factor yaet precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.


ensembl_gene_id: PAU_00654
symbol: lpxD
gene_biotype: protein_coding
description:
  Udp-3-o-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: PAU_00655
symbol: fabZ
gene_biotype: protein_coding
description:
  (3r)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: PAU_00656
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PAU_00657
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase); Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PAU_00660
symbol: accA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: PAU_00661
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA (ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: PAU_00663
symbol: cutF
gene_biotype: protein_coding
description:
  Copper homeostasis protein (lipoprotein); This family represents a bacterial outer membrane lipoprotein that is necessary for signalling by the Cpx pathway. This pathway responds to cell envelope disturbances and increases the expression of periplasmic protein folding and degradation factors. While the molecular function of the NlpE protein is unknown, it may be involved in detecting bacterial adhesion to abiotic surfaces.


ensembl_gene_id: PAU_00664
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: PAU_00666
symbol: rcsF
gene_biotype: protein_coding
description:
  Exopolysaccharide synthesis regulatory protein rcsf; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.


ensembl_gene_id: PAU_00669
symbol: metN
gene_biotype: protein_coding
description:
  Methionine import ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PAU_00675
symbol: ygcF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: PAU_00677
symbol: cysJ
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family.


ensembl_gene_id: PAU_00678
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: PAU_00679
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: PAU_00681
symbol: cysG
gene_biotype: protein_coding
description:
  Sirohaem synthase-uroporphyrinogen III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: PAU_00685
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein ftsb; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: PAU_00686
symbol: ispD
gene_biotype: protein_coding
description:
  2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.


ensembl_gene_id: PAU_00687
symbol: ispF
gene_biotype: protein_coding
description:
  2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: PAU_00688
symbol: truD
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: PAU_00689
symbol: surE
gene_biotype: protein_coding
description:
  Multifunctional protein SurE; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.


ensembl_gene_id: PAU_00690
symbol: pcm
gene_biotype: protein_coding
description:
  Protein-l-isoaspartate o-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: PAU_00692
symbol: rpoS
gene_biotype: protein_coding
description:
  Rna polymerase sigma factor (sigma-38); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: PAU_00696
symbol: mutS
gene_biotype: protein_coding
description:
  Dna mismatch repair protein muts; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: PAU_00704
symbol: fucA
gene_biotype: protein_coding
description:
  L-fuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.


ensembl_gene_id: PAU_00732
symbol: mrfG-2
gene_biotype: protein_coding
description:
  Putative minor fimbrial subunit; Members of this family of bacterial proteins are involved in regulation of length and mediation of adhesion of fimbriae. Fimbriae (also called pili), are polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers, that enable bacteria to colonize the epithelium of specific host organs. Fimbriae are also responsible to promote virulence.


ensembl_gene_id: PAU_00736
symbol: purA1
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase 1; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: PAU_00739
symbol: hisA2
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino imidazole-4-carboxamide isomerase 2.


ensembl_gene_id: PAU_00743
symbol: fdoH2
gene_biotype: protein_coding
description:
  Putative formate dehydrogenase-o, iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: PAU_00749
symbol: yeeO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Characterised members of the Multi Antimicrobial Extrusion (MATE) family function as drug/sodium antiporters. These proteins mediate resistance to a wide range of cationic dyes, fluroquinolones, aminoglycosides and other structurally diverse antibodies and drugs.


ensembl_gene_id: PAU_00753
symbol: PAU_00753
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: PAU_00761
symbol: PAU_00761
gene_biotype: protein_coding
description:
  Putative transport protein; The MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients.


ensembl_gene_id: PAU_00762
symbol: fbpC
gene_biotype: protein_coding
description:
  Ferric cations import ATP-binding protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PAU_00763
symbol: afuB
gene_biotype: protein_coding
description:
  Putative permease component of transport system for ferric iro (putative ferric transport system permease).


ensembl_gene_id: PAU_00771
symbol: ampC
gene_biotype: protein_coding
description:
  Beta-lactamases are enzymes which catalyse the hydrolysis of an amide bond in the beta-lactam ring of antibiotics belonging to the penicillin/cephalosporin family.


ensembl_gene_id: PAU_00775
symbol: agaV
gene_biotype: protein_coding
description:
  Pts system, n-acetylgalactosamine-specific iib component 2 (eiib-aga' (n-acetylgalactosamine-permease iib component 2) (phosphotransferas enzyme ii, b component 2).


ensembl_gene_id: PAU_00776
symbol: agaC
gene_biotype: protein_coding
description:
  Pts system, n-acetylgalactosamine-specific iic component 1 (eiic-aga (n-acetylgalactosamine-permease iic component 1).


ensembl_gene_id: PAU_00777
symbol: agaD
gene_biotype: protein_coding
description:
  Pts system, n-acetylgalactosamine-specific iid component (eiid-aga (n-acetylgalactosamine-permease iid component) (phosphotransferas enzyme ii, d component).


ensembl_gene_id: PAU_00794
symbol: speD
gene_biotype: protein_coding
description:
  S-adenosylmethionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.


ensembl_gene_id: PAU_00795
symbol: speE
gene_biotype: protein_coding
description:
  Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: PAU_00798
symbol: hpt
gene_biotype: protein_coding
description:
  Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: PAU_00799
symbol: chpB
gene_biotype: protein_coding
description:
  Pemk-like protein 2; Bacterial cells remove plasmid-free segregants by the use of toxin/antitoxin systems, where cells that lack plasmids cannot produce the antitoxin required for survival. Several of the toxin components have similar structures, which consists of an SH3-like barrel fold, and contains an inserted beta-sheet subdomain and a C-terminal helix, despite often low sequence identities. Toxins that have this structural fold include CcdB from Escherichia coli, a topoisomerase poison that interferes with DNA gyrase activity, PemK-like YdcE from Bacillus subtilis, Kid toxin (Kis  [...]


ensembl_gene_id: PAU_00801
symbol: yadF
gene_biotype: protein_coding
description:
  Similar to putative carbonic anhydrase yadf of escherichia coli; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: PAU_00804
symbol: panD
gene_biotype: protein_coding
description:
  Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: PAU_00805
symbol: panC
gene_biotype: protein_coding
description:
  Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: PAU_00806
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: PAU_00808
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: PAU_00809
symbol: yadB
gene_biotype: protein_coding
description:
  Glutamyl-q tRNA(asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: PAU_00810
symbol: dksA
gene_biotype: protein_coding
description:
  Dnak suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: PAU_00814
symbol: mrcB
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: PAU_00826
symbol: btuF
gene_biotype: protein_coding
description:
  Vitamin b12-binding protein precursor; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.


ensembl_gene_id: PAU_00827
symbol: mtnA
gene_biotype: protein_coding
description:
  Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP  [...]


ensembl_gene_id: PAU_00828
symbol: dgt
gene_biotype: protein_coding
description:
  Deoxyguanosinetriphosphate triphosphohydrolase; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily.


ensembl_gene_id: PAU_00830
symbol: rumA
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: PAU_00831
symbol: relA
gene_biotype: protein_coding
description:
  Gtp pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: PAU_00840
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: PAU_00841
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: PAU_00851
symbol: tmk
gene_biotype: protein_coding
description:
  Similarities with thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: PAU_00858
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase (glyoxalase ii); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: PAU_00860
symbol: rnhA
gene_biotype: protein_coding
description:
  Putative DNA replication ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.


ensembl_gene_id: PAU_00861
symbol: dnaQ
gene_biotype: protein_coding
description:
  Putative DNA polymerase III epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: PAU_00868
symbol: tktA
gene_biotype: protein_coding
description:
  Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: PAU_00877
symbol: epd
gene_biotype: protein_coding
description:
  D-erythrose 4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: PAU_00879
symbol: fba
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: PAU_00883
symbol: phbG
gene_biotype: protein_coding
description:
  Putative photobactin biosynthesis protein phbg; This domain is found in many multi-domain enzymes which synthesize peptide antibiotics.


ensembl_gene_id: PAU_00887
symbol: phuG
gene_biotype: protein_coding
description:
  Cytoplasmic membrane permease (ferric vibriobactin abc transporter permease protein); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PAU_00888
symbol: phuD
gene_biotype: protein_coding
description:
  Ferric enterobactin transport protein fepg; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PAU_00906
symbol: PAU_00906
gene_biotype: protein_coding
description:
  Filamentous haemagglutinin family protein; This highly divergent repeat occurs in number of proteins implicated in cell aggregation.


ensembl_gene_id: PAU_00908
symbol: yhiP
gene_biotype: protein_coding
description:
  Similar to putative di-tripeptide transporter protein yhip of escherichia coli; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily.


ensembl_gene_id: PAU_00910
symbol: hpaB-2
gene_biotype: protein_coding
description:
  4-hydroxyphenylacetate 3-monooxygenase, oxygenase component (4-hpa 3 monooxygenase large component) (4-hpa 3-hydroxylase).


ensembl_gene_id: PAU_00915
symbol: pfaC
gene_biotype: protein_coding
description:
  Polyunsaturated fatty acid synthase pfac; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: PAU_00927
symbol: gabD
gene_biotype: protein_coding
description:
  Succinate-semialdehyde dehydrogenase, nadp-dependent activit (succinate-semialdehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PAU_00928
symbol: bcr
gene_biotype: protein_coding
description:
  Multidrug resistance proteins are molecular pumps that participate in a low energy shock adaptive response in some bacteria. They mediate cellular resistance to toxicants such as cycloheximide (CYH), 4-nitroquinoline N-oxide (4-NQO), cadmium, and hydrogen peroxide in yeast.


ensembl_gene_id: PAU_00931
symbol: hpaE
gene_biotype: protein_coding
description:
  5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PAU_00970
symbol: ngrA
gene_biotype: protein_coding
description:
  4'-phosphopantetheinyl tranferase; Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: PAU_00973
symbol: yraI
gene_biotype: protein_coding
description:
  Uncharacterized fimbrial chaperone yrai precursor; The PapD-like superfamily of periplasmic chaperones directs the assembly of over 30 diverse adhesive surface organelles that mediate the attachment of many different pathogenic bacteria to host tissues, a critical early step in the development of disease. PapD, the prototypical chaperone, is necessary for the assembly of P pili.


ensembl_gene_id: PAU_00977
symbol: ybaL
gene_biotype: protein_coding
description:
  Similar to putative transport protein ybal of escherichia coli; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: PAU_00991
symbol: PAU_00991
gene_biotype: protein_coding
description:
  Bacterial luciferase-similar to putative monooxygenase ycdm of escherichia coli; Bacterial luciferase is a flavin monooxygenase that catalyses the oxidation of long-chain aldehydes and releases energy in the form of visible light, and which uses flavin as a substrate rather than a cofactor.


ensembl_gene_id: PAU_00994
symbol: PAU_00994
gene_biotype: protein_coding
description:
  Lumazine binding protein, similar to riboflavin synthase; Lumazine protein (LumP) (gene luxL). LumP is a protein that modulates the colour of the bioluminescence emission of bacterial luciferase.


ensembl_gene_id: PAU_00996
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: PAU_00997
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase catalytic subunit (ai carboxylase) (airc); Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: PAU_00998
symbol: lpxH
gene_biotype: protein_coding
description:
  Udp-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: PAU_00999
symbol: ppiB
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: PAU_01002
symbol: folD
gene_biotype: protein_coding
description:
  Bifunctional protein fold; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: PAU_01028
symbol: cspI
gene_biotype: protein_coding
description:
  'cold shock' proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature.


ensembl_gene_id: PAU_01061
symbol: sycD
gene_biotype: protein_coding
description:
  Yopb/d chaperone sycd; The type III secretion system of Gram-negative bacteria is used to transport virulence factors from the pathogen directly into the host cell and is only triggered when the bacterium comes into close contact with the host. Effector proteins secreted by the type III system do not possess a secretion signal, and are considered unique because of this. Yersinia spp. secrete effector proteins called YopB and YopD that facilitate the spread of other translocated proteins through the type III needle and the host cell cytoplasm. Both are believed to act as pore translocas [...]


ensembl_gene_id: PAU_01065
symbol: exsC
gene_biotype: protein_coding
description:
  Similar to the exoenzyme s synthesis protein c exsc; In many Gram-negative bacteria, a key indicator of pathogenic potential is the possession of a specialised type III secretion system, which is utilised to deliver virulence effector proteins directly into the host cell cytosol. Many of the proteins secreted from such systems require small cytosolic chaperones to maintain the secreted substrates in a secretion-competent state.


ensembl_gene_id: PAU_01069
symbol: orf35
gene_biotype: protein_coding
description:
  Holins act against the host cell membrane to allow lytic enzymes of the phage to reach the bacterial cell wall.


ensembl_gene_id: PAU_01071
symbol: Rz
gene_biotype: protein_coding
description:
  Similar to probable endopeptidase gp15 protein of lamdoid prophage; Many bacteriophages with Gram-negative hosts contain two auxiliary lysis genes Rz and Rz1. Both of these genes are required for host cell lysis if the outer membrane is stabilized by millimolar concentrations of divalent cations, but are otherwise uneccessary. The Rz protein is believed to posses endopeptidase activity, while Rz1 encodes a prolipoprotein which, after cleavage by a signal peptidase, is located in the outer membrane.


ensembl_gene_id: PAU_01074
symbol: wzb
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: PAU_01081
symbol: aldB
gene_biotype: protein_coding
description:
  Aldehyde dehydrogenase b (lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: PAU_01087
symbol: metK
gene_biotype: protein_coding
description:
  S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: PAU_01089
symbol: speB
gene_biotype: protein_coding
description:
  Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.


ensembl_gene_id: PAU_01091
symbol: PAU_01091
gene_biotype: protein_coding
description:
  This family contains a number of integral membrane proteins including the TerC protein. TerC has been implicated in resistance to tellurium, and may be involved in efflux of tellurium ions.


ensembl_gene_id: PAU_01092
symbol: mutH
gene_biotype: protein_coding
description:
  Dna mismatch repair protein muth (methyl-directed mismatch repai protein); Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: PAU_01093
symbol: sgrR
gene_biotype: protein_coding
description:
  Hth-type transcriptional regulator sgrr; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain.


ensembl_gene_id: PAU_01094
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: PAU_01095
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: PAU_01096
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: PAU_01097
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: PAU_01098
symbol: leuO
gene_biotype: protein_coding
description:
  Probable hth-type transcriptional regulator leuo; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_01102
symbol: ilvH
gene_biotype: protein_coding
description:
  Acetolactate synthase isozyme iii small subunit (ahas-iii (acetohydroxy-acid synthase iii small subunit) (als-iii).


ensembl_gene_id: PAU_01104
symbol: mraZ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein mraz; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.


ensembl_gene_id: PAU_01105
symbol: mraW
gene_biotype: protein_coding
description:
  S-adenosyl-l-methionine-dependent methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: PAU_01106
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein ftsl; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: PAU_01107
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan synthetase ftsi (penicillin-binding protein 3) (pbp-3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: PAU_01108
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: PAU_01109
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-ala nine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: PAU_01110
symbol: mraY
gene_biotype: protein_coding
description:
  phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: PAU_01111
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: PAU_01112
symbol: ftsW
gene_biotype: protein_coding
description:
  Membrane protein ftsw, involved in peptidoglycan biosynthesis; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: PAU_01113
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: PAU_01115
symbol: ddlB
gene_biotype: protein_coding
description:
  D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.


ensembl_gene_id: PAU_01116
symbol: ftsQ
gene_biotype: protein_coding
description:
  Cell division protein ftsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: PAU_01117
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein ftsa; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: PAU_01118
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein ftsz; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: PAU_01119
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: PAU_01121
symbol: secM
gene_biotype: protein_coding
description:
  Secretion monitor precursor; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.


ensembl_gene_id: PAU_01122
symbol: secA
gene_biotype: protein_coding
description:
  Preprotein translocase seca subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: PAU_01123
symbol: mutT
gene_biotype: protein_coding
description:
  8-oxo-dGTP diphosphatase; Mutator mutt protein (7,8-dihydro-8-oxoguanine-triphosphatase) (8-oxo dgtpase) (dgtp pyrophosphohydrolase); Belongs to the Nudix hydrolase family.


ensembl_gene_id: PAU_01124
symbol: yacG
gene_biotype: protein_coding
description:
  Upf0243 zinc-binding protein yacg; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: PAU_01125
symbol: yacF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: PAU_01126
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: PAU_01128
symbol: hofB
gene_biotype: protein_coding
description:
  Putative integral membrane protein involved in biogenesis of fimbriae protein transport, dna uptake (putative integral membrane protei hofb).


ensembl_gene_id: PAU_01138
symbol: aceE
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PAU_01139
symbol: aceF
gene_biotype: protein_coding
description:
  Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenas complex (e2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: PAU_01141
symbol: acnB
gene_biotype: protein_coding
description:
  Aconitate hydratase 2 (citrate hydro-lyase 2) (aconitase 2); Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: PAU_01148
symbol: argO
gene_biotype: protein_coding
description:
  Arginine exporter protein argo; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family.


ensembl_gene_id: PAU_01150
symbol: iciA
gene_biotype: protein_coding
description:
  Chromosome initiation inhibitor (oric replication inhibitor); Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_01151
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: PAU_01152
symbol: serA
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PAU_01153
symbol: ygfA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Similar to putative ligase ygfa of escherichia coli; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: PAU_01154
symbol: ygfE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: PAU_01156
symbol: pepP
gene_biotype: protein_coding
description:
  Xaa-pro aminopeptidase (x-pro aminopeptidase) (aminopeptidase p ii (app-ii) (aminoacylproline aminopeptidase).


ensembl_gene_id: PAU_01160
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system h protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: PAU_01161
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: PAU_01177
symbol: goaG
gene_biotype: protein_coding
description:
  4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PAU_01198
symbol: PAU_01198
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Similar to uncharacterized low-complexity pentapeptide repeat precursor.


ensembl_gene_id: PAU_01207
symbol: ygfZ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.


ensembl_gene_id: PAU_01210
symbol: fldB
gene_biotype: protein_coding
description:
  Flavodoxin-2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: PAU_01211
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase xerd; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges t [...]


ensembl_gene_id: PAU_01212
symbol: dsbC
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein dsbc precursor; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: PAU_01215
symbol: PAU_01215
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Similar to pyocin s3 immunity protein and to photorhabdus luminescen proteins.


ensembl_gene_id: PAU_01217
symbol: col
gene_biotype: protein_coding
description:
  Pyocins are polypeptide toxins produced by, and active against, bacteria. S-type pyocins cause cell death by DNA breakdown due to endonuclease activity.


ensembl_gene_id: PAU_01218
symbol: imm
gene_biotype: protein_coding
description:
  Colicin-e7 immunity protein (imme7) (microcin-e7 immunity protein); This family includes bacterial colicin and pyocin immunity proteins,. These immunity proteins can bind specifically to the DNase-type colicins and pyocins and inhibit their bactericidal activity.


ensembl_gene_id: PAU_01219
symbol: col-2
gene_biotype: protein_coding
description:
  Similar to pyocin s2 and s1 and colicin-e9; Bacteriocins are protein antibiotics that kill bacteria closely related to the producing species. Colicins are a subgroup of bacteriocins that are produced by and target. The lethal action of most colicins is exerted either by formation of a pore in the cytoplasmic membrane of the target cell, or by an enzymatic nuclease digestion mechanism. Most colicins are able to translocate the outer membrane by a two-receptor system, where one receptor is used for the initial binding and the second for translocation. The initial binding is to cell surfa [...]


ensembl_gene_id: PAU_01220
symbol: PAU_01220
gene_biotype: protein_coding
description:
  Similar to colicin/pyocin immunity protein; This family includes bacterial colicin and pyocin immunity proteins,. These immunity proteins can bind specifically to the DNase-type colicins and pyocins and inhibit their bactericidal activity.


ensembl_gene_id: PAU_01225
symbol: prfB
gene_biotype: protein_coding
description:
  Peptide chain release factor 2 (rf-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: PAU_01233
symbol: prpR
gene_biotype: protein_coding
description:
  Propionate catabolism operon regulatory protein; Transcriptional activators which activates catabolism of propionate.


ensembl_gene_id: PAU_01234
symbol: prpB
gene_biotype: protein_coding
description:
  Methylisocitrate lyase (2-methylisocitrate lyase); Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: PAU_01235
symbol: prpC
gene_biotype: protein_coding
description:
  2-methylcitrate synthase (methylcitrate synthase) (citrate synthas 2); Belongs to the citrate synthase family.


ensembl_gene_id: PAU_01243
symbol: norM
gene_biotype: protein_coding
description:
  Probable multidrug resistance protein norm (multidrug-efflu transporter); Multidrug resistance protein.


ensembl_gene_id: PAU_01246
symbol: PAU_01246
gene_biotype: protein_coding
description:
  Similarities with heme receptor hasr/tonb-dependent receptor; This entry represents the TonB-dependent outer membrane haem/haemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain haemoglobin or other haem-bearing globins) or legumes (which contain leghaemoglobin).


ensembl_gene_id: PAU_01247
symbol: tonB
gene_biotype: protein_coding
description:
  Similarities with energy transducer tonb. putative secreted protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: PAU_01261
symbol: scrB
gene_biotype: protein_coding
description:
  Sucrose-6-phosphate hydrolase; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.


ensembl_gene_id: PAU_01269
symbol: smpB
gene_biotype: protein_coding
description:
  Small protein b-RNA Binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome t [...]


ensembl_gene_id: PAU_01272
symbol: smpA
gene_biotype: protein_coding
description:
  Membrane protein-small protein a; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PAU_01273
symbol: recN
gene_biotype: protein_coding
description:
  Dna repair protein recn (recombination protein n); May be involved in recombinational repair of damaged DNA.


ensembl_gene_id: PAU_01274
symbol: ppnK
gene_biotype: protein_coding
description:
  Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: PAU_01276
symbol: ung
gene_biotype: protein_coding
description:
  uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: PAU_01283
symbol: idi
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: PAU_01296
symbol: srmB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: PAU_01297
symbol: yfiC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: PAU_01300
symbol: rseA
gene_biotype: protein_coding
description:
  Sigma-e factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...]


ensembl_gene_id: PAU_01303
symbol: lepA
gene_biotype: protein_coding
description:
  Gtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: PAU_01305
symbol: rnc
gene_biotype: protein_coding
description:
  Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: PAU_01306
symbol: era
gene_biotype: protein_coding
description:
  Gtp-binding protein era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: PAU_01307
symbol: recO
gene_biotype: protein_coding
description:
  Dna repair protein reco (recombination protein o); Involved in DNA repair and RecF pathway recombination.


ensembl_gene_id: PAU_01308
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: PAU_01309
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: PAU_01320
symbol: tadA
gene_biotype: protein_coding
description:
  Similar to ecoli yfhc protein, tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: PAU_01322
symbol: yfhD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: PAU_01324
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: PAU_01329
symbol: nadE
gene_biotype: protein_coding
description:
  Nh(3)-dependent nad+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.


ensembl_gene_id: PAU_01337
symbol: PAU_01337
gene_biotype: protein_coding
description:
  Putative protein involved in amino acid adenylation; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: PAU_01352
symbol: hmpA
gene_biotype: protein_coding
description:
  Flavohemoprotein (hemoglobin-like protein); Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: PAU_01354
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: PAU_01357
symbol: treB
gene_biotype: protein_coding
description:
  Pts system, trehalose-specific iibc component (eiibc-tre) (trehalose permease iibc component) (phosphotransferase enzyme ii, bc component (eii-tre).


ensembl_gene_id: PAU_01360
symbol: trmJ
gene_biotype: protein_coding
description:
  tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: PAU_01361
symbol: iscR
gene_biotype: protein_coding
description:
  Hth-type transcriptional regulator iscr; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: PAU_01362
symbol: iscS-2
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: PAU_01363
symbol: nifU
gene_biotype: protein_coding
description:
  Nifu protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: PAU_01364
symbol: iscA
gene_biotype: protein_coding
description:
  Iron-binding protein isca (iron-sulfur cluster assembly protein); Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.


ensembl_gene_id: PAU_01365
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone protein hscb (hsc20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: PAU_01366
symbol: hscA
gene_biotype: protein_coding
description:
  Chaperone protein hsca (hsc66); Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.


ensembl_gene_id: PAU_01382
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: PAU_01383
symbol: yfgB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: PAU_01385
symbol: yfgA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. Belongs to the RodZ family.


ensembl_gene_id: PAU_01386
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: PAU_01389
symbol: bamB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PAU_01390
symbol: engA
gene_biotype: protein_coding
description:
  Gtp-binding protein enga (double era-like domain protein); GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: PAU_01393
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen 3 oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: PAU_01398
symbol: cysU
gene_biotype: protein_coding
description:
  Molybdenum transport system permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PAU_01400
symbol: cysA
gene_biotype: protein_coding
description:
  Sulfate/thiosulfate import ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PAU_01403
symbol: ptsI
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate-protein phosphotransferase (phosphotransferas system, enzyme i); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: PAU_01406
symbol: cysZ
gene_biotype: protein_coding
description:
  Sulfate transport protein cysz involved in cysteine synthesis; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: PAU_01407
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein zipa homolog; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: PAU_01408
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: PAU_01411
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: PAU_01416
symbol: fadI
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: PAU_01417
symbol: fadJ
gene_biotype: protein_coding
description:
  Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PAU_01421
symbol: hutG
gene_biotype: protein_coding
description:
  Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: PAU_01426
symbol: prmB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: PAU_01427
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: PAU_01433
symbol: yfcK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: PAU_01438
symbol: fabB
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase i (beta-ketoacyl-ac synthase i) (kas i); Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: PAU_01449
symbol: pdxB
gene_biotype: protein_coding
description:
  Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: PAU_01451
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: PAU_01453
symbol: accD
gene_biotype: protein_coding
description:
  Acetyl-coenzyme a carboxylase carboxyl transferase subunit bet (accase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: PAU_01454
symbol: folC
gene_biotype: protein_coding
description:
  Folylpolyglutamate synthase-folc bifunctional protein; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.


ensembl_gene_id: PAU_01455
symbol: dedD
gene_biotype: protein_coding
description:
  Putative membrane protein; Non-essential cell division protein that could be required for efficient cell constriction.


ensembl_gene_id: PAU_01457
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: PAU_01458
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: PAU_01468
symbol: lsrG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.


ensembl_gene_id: PAU_01469
symbol: yneB
gene_biotype: protein_coding
description:
  Putative aldolase yneb; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family.


ensembl_gene_id: PAU_01471
symbol: lsrK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.


ensembl_gene_id: PAU_01473
symbol: cdiA
gene_biotype: protein_coding
description:
  Putative haemagglutinin cdia; A number of the members of this family have been designated adhesins, filamentous haemagglutinins, heme/hemopexin-binding protein, etc.


ensembl_gene_id: PAU_01489
symbol: PAU_01489
gene_biotype: protein_coding
description:
  Putative hemolysin activator hlyb; Haemolysin and related toxins are secreted across both the cytoplasmic and outer membranes of Gram-negative bacteria in a process which proceeds without a periplasmic intermediate.


ensembl_gene_id: PAU_01497
symbol: argM
gene_biotype: protein_coding
description:
  Succinylornithine transaminase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: PAU_01499
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: PAU_01500
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: PAU_01501
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: PAU_01512
symbol: pta
gene_biotype: protein_coding
description:
  Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: PAU_01513
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: PAU_01516
symbol: yfbR
gene_biotype: protein_coding
description:
  5'-nucleotidase yfbr; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: PAU_01520
symbol: nuoA
gene_biotype: protein_coding
description:
  Nadh-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: PAU_01521
symbol: nuoB
gene_biotype: protein_coding
description:
  Nadh dehydrogenase i chain b (nadh-ubiquinone oxidoreductase chain 2 (nuo2); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PAU_01522
symbol: nuoC
gene_biotype: protein_coding
description:
  Nadh dehydrogenase i chain c/d (nadh-ubiquinone oxidoreductase chai 3/4) (nuo3/nuo4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: PAU_01524
symbol: nuoF
gene_biotype: protein_coding
description:
  Nadh dehydrogenase i chain f (nadh-ubiquinone oxidoreductase chain 6 (nuo6); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: PAU_01525
symbol: nuoG
gene_biotype: protein_coding
description:
  Nadh-quinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: PAU_01526
symbol: nuoH
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: PAU_01527
symbol: nuoI
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PAU_01528
symbol: nuoJ
gene_biotype: protein_coding
description:
  Nadh dehydrogenase i chain j (nadh-ubiquinone oxidoreductase chain j); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: PAU_01529
symbol: nuoK
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: PAU_01532
symbol: nuoN
gene_biotype: protein_coding
description:
  NADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.


ensembl_gene_id: PAU_01538
symbol: menD
gene_biotype: protein_coding
description:
  Menaquinone biosynthesis protein mend; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: PAU_01539
symbol: mhpC3
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: PAU_01540
symbol: menB
gene_biotype: protein_coding
description:
  Naphthoate synthase (dihydroxynaphthoic acid synthetase) (dhn synthetase); Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: PAU_01541
symbol: menC
gene_biotype: protein_coding
description:
  O-succinylbenzoate-coa synthase (osb synthase) (4-(2'-carboxyphenyl) 4-oxybutyric acid synthase); Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB).


ensembl_gene_id: PAU_01555
symbol: nrdB
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotid reductase 1) (b2 protein) (r2 protein).


ensembl_gene_id: PAU_01556
symbol: nrdA
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase 1 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: PAU_01557
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: PAU_01558
symbol: gyrA
gene_biotype: protein_coding
description:
  Dna gyrase subunit a; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: PAU_01559
symbol: rcsC
gene_biotype: protein_coding
description:
  Sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.


ensembl_gene_id: PAU_01560
symbol: rcsB
gene_biotype: protein_coding
description:
  Capsular synthesis regulator component b; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.


ensembl_gene_id: PAU_01561
symbol: yojN
gene_biotype: protein_coding
description:
  Putative 2-component sensor protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.


ensembl_gene_id: PAU_01601
symbol: cbiA
gene_biotype: protein_coding
description:
  Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.


ensembl_gene_id: PAU_01602
symbol: cobD
gene_biotype: protein_coding
description:
  Cobalamin biosynthesis protein cobd; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.


ensembl_gene_id: PAU_01604
symbol: cbiD
gene_biotype: protein_coding
description:
  Putative cobalt-precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.


ensembl_gene_id: PAU_01611
symbol: cbiK
gene_biotype: protein_coding
description:
  Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family.


ensembl_gene_id: PAU_01612
symbol: cbiL
gene_biotype: protein_coding
description:
  Precorrin-2 c20-methyltransferase (s-adenosyl-l-methionine--precorrin 2 methyltransferase) (sp2mt); Belongs to the precorrin methyltransferase family.


ensembl_gene_id: PAU_01613
symbol: cobQ
gene_biotype: protein_coding
description:
  Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: PAU_01614
symbol: cobU
gene_biotype: protein_coding
description:
  Bifunctional cobalamin biosynthesis protein cobu; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: PAU_01615
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: PAU_01618
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: PAU_01621
symbol: PAU_01621
gene_biotype: protein_coding
description:
  Virulence protein Hcp1 from Pseudomonas aeruginosa. Hcp1 appears to be part of a protein secretion apparatus that is required for virulence.


ensembl_gene_id: PAU_01638
symbol: btuR
gene_biotype: protein_coding
description:
  Cob(i)alamin adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: PAU_01665
symbol: rplY
gene_biotype: protein_coding
description:
  50s ribosomal protein l25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: PAU_01668
symbol: rsuA
gene_biotype: protein_coding
description:
  Ribosomal small subunit pseudouridine synthase A; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PAU_01669
symbol: bcr-2
gene_biotype: protein_coding
description:
  Multidrug resistance proteins are molecular pumps that participate in a low energy shock adaptive response in some bacteria.


ensembl_gene_id: PAU_01673
symbol: lpxT
gene_biotype: protein_coding
description:
  Similar to putative membrane protein yeiu of escherichia coli; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.


ensembl_gene_id: PAU_01679
symbol: nfo
gene_biotype: protein_coding
description:
  Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: PAU_01681
symbol: yeiE
gene_biotype: protein_coding
description:
  Transcriptional regulator lysr-type yeie o escherichia coli; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_01684
symbol: PAU_01684
gene_biotype: protein_coding
description:
  Similar to hemin/siderophore abc transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PAU_01690
symbol: dld
gene_biotype: protein_coding
description:
  D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: PAU_01696
symbol: rne
gene_biotype: protein_coding
description:
  Rnase e, membrane attachment, mrna turnover, maturation 5s rna (rnas e); Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: PAU_01697
symbol: rluC
gene_biotype: protein_coding
description:
  23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PAU_01698
symbol: yceF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: PAU_01701
symbol: plsX
gene_biotype: protein_coding
description:
  Fatty acid/phospholipid synthesis protein plsx; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: PAU_01702
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: PAU_01704
symbol: fabG
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PAU_01705
symbol: acpP
gene_biotype: protein_coding
description:
  Acyl carrier protein (cytosolic activating factor) (caf); Carrier of the growing fatty acid chain in fatty acid biosynthesis.


ensembl_gene_id: PAU_01706
symbol: fabF
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase ii; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: PAU_01708
symbol: yceG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: PAU_01709
symbol: tmk-2
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: PAU_01713
symbol: ycfM
gene_biotype: protein_coding
description:
  Putative outer membrane lipoprotein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.


ensembl_gene_id: PAU_01716
symbol: nagZ
gene_biotype: protein_coding
description:
  Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: PAU_01723
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor (trcf); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: PAU_01727
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein-releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: PAU_01730
symbol: pepT
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: PAU_01737
symbol: trmU
gene_biotype: protein_coding
description:
  Trna (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family.


ensembl_gene_id: PAU_01754
symbol: crcA
gene_biotype: protein_coding
description:
  Crca protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.


ensembl_gene_id: PAU_01765
symbol: baeS
gene_biotype: protein_coding
description:
  Sensory histidine kinase protein; Two-component signal transduction systems enable bacteria to sense, respond, and adapt to a wide range of environments, stressors, and growth conditions. Some bacteria can contain up to as many as 200 two-component systems that need tight regulation to prevent unwanted cross-talk. These pathways have been adapted to respond to a wide variety of stimuli, including nutrients, cellular redox state, changes in osmolarity, quorum signals and antibiotics.


ensembl_gene_id: PAU_01766
symbol: mdtC
gene_biotype: protein_coding
description:
  Multidrug resistance protein mdtc (multidrug transporter mdtc); The Escherichia coli acrA and acrB genes encode a multi-drug efflux system that is believed to protect the bacterium against hydrophobic inhibitors. E. coli AcrB is a transporter that is energized by proton-motive force and that shows the widest substrate specificity among all known multidrug pumps, ranging from most of the currently used antibiotics, disinfectants, dyes, and detergents to simple solvents; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.


ensembl_gene_id: PAU_01767
symbol: mdtB
gene_biotype: protein_coding
description:
  Multidrug resistance protein mdtb (multidrug transporter mdtb); The Escherichia coli acrA and acrB genes encode a multi-drug efflux system that is believed to protect the bacterium against hydrophobic inhibitors. E. coli AcrB is a transporter that is energized by proton-motive force and that shows the widest substrate specificity among all known multidrug pumps, ranging from most of the currently used antibiotics, disinfectants, dyes, and detergents to simple solvents; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.


ensembl_gene_id: PAU_01768
symbol: mdtA
gene_biotype: protein_coding
description:
  Multidrug resistance protein mdta precursor (multidrug transporte mdta); The Escherichia coli acrA and acrB genes encode a multi-drug efflux system that is believed to protect the bacterium against hydrophobic inhibitors. E. coli AcrB is a transporter that is energized by proton-motive force and that shows the widest substrate specificity among all known multidrug pumps, ranging from most of the currently used antibiotics, disinfectants, dyes, and detergents to simple solvents; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PAU_01777
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: PAU_01779
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: PAU_01781
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: PAU_01786
symbol: celC
gene_biotype: protein_coding
description:
  Pts system, cellobiose-specific iia component (eiia-cel) (cellobiose permease iia component) (phosphotransferase enzyme ii, a component (eiii-cel).


ensembl_gene_id: PAU_01787
symbol: celB
gene_biotype: protein_coding
description:
  Phosphotransferase system cellobiose-specific component iic; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.


ensembl_gene_id: PAU_01789
symbol: hda
gene_biotype: protein_coding
description:
  Dnaa-homolog protein hda; Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA; Belongs to the DnaA family. HdA subfamily.


ensembl_gene_id: PAU_01791
symbol: yfgC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: PAU_01796
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: PAU_01797
symbol: nlpB
gene_biotype: protein_coding
description:
  Lipoprotein-34; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: PAU_01814
symbol: ypfI
gene_biotype: protein_coding
description:
  Putative acyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: PAU_01817
symbol: dapE
gene_biotype: protein_coding
description:
  N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: PAU_01825
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: PAU_01826
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: PAU_01833
symbol: yebN
gene_biotype: protein_coding
description:
  Upf0059 inner membrane protein plu2701; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: PAU_01835
symbol: manZ
gene_biotype: protein_coding
description:
  Pts system, mannose-specific iid component (eiid-man) (mannose permease iid component) (phosphotransferase enzyme ii, d component (eii-m-man).


ensembl_gene_id: PAU_01836
symbol: manY
gene_biotype: protein_coding
description:
  Pts system, mannose-specific iic component (eiic-man) (mannose permease iic component) (phosphotransferase enzyme ii, c component (eii-p-man).


ensembl_gene_id: PAU_01837
symbol: manX
gene_biotype: protein_coding
description:
  Pts system, mannose-specific iiab component (eiiab-man) (mannose permease iiab component) (phosphotransferase enzyme ii, ab component (eiii-man).


ensembl_gene_id: PAU_01853
symbol: proQ
gene_biotype: protein_coding
description:
  Prop effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.


ensembl_gene_id: PAU_01856
symbol: ydjN
gene_biotype: protein_coding
description:
  Similar to proton/sodium-glutamate symport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PAU_01864
symbol: PAU_01864
gene_biotype: protein_coding
description:
  Iron (chelated) abc transporter, periplasmic-binding protein yfea; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: PAU_01866
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: PAU_01867
symbol: infC
gene_biotype: protein_coding
description:
  Translation initiation factor if-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: PAU_01869
symbol: rplT
gene_biotype: protein_coding
description:
  50s ribosomal protein l20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: PAU_01870
symbol: pheS
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: PAU_01871
symbol: pheT
gene_biotype: protein_coding
description:
  phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: PAU_01872
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor subunit alpha (ihf-alpha); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: PAU_01873
symbol: btuC
gene_biotype: protein_coding
description:
  Vitamin b12 import system permease protein btuc; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.


ensembl_gene_id: PAU_01874
symbol: btuD
gene_biotype: protein_coding
description:
  Vitamin B12 import ATP-binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PAU_01875
symbol: arnB
gene_biotype: protein_coding
description:
  UDP-4-amino-4-deoxy-l-arabinose--oxoglutarate aminotransferase; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: PAU_01876
symbol: arnC
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate 4-deoxy-4-formamido-l-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: PAU_01877
symbol: arnA
gene_biotype: protein_coding
description:
  Bifunctional polymyxin resistance protein; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily.


ensembl_gene_id: PAU_01878
symbol: arnD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: PAU_01879
symbol: arnT
gene_biotype: protein_coding
description:
  Undecaprenyl phosphate-alpha-4-amino-4-deoxy-l-arabinose arabinosy transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.


ensembl_gene_id: PAU_01880
symbol: PAU_01880
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.


ensembl_gene_id: PAU_01881
symbol: yfbJ
gene_biotype: protein_coding
description:
  Upf0188 putative innermembrane protein pbge3; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: PAU_01895
symbol: hmuV
gene_biotype: protein_coding
description:
  Hemin import atp-binding protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.


ensembl_gene_id: PAU_01896
symbol: PAU_01896
gene_biotype: protein_coding
description:
  Putative hemin permease; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PAU_01900
symbol: aroH
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: PAU_01901
symbol: ydiA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: PAU_01902
symbol: ppsA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase (pep synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: PAU_01905
symbol: menI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).


ensembl_gene_id: PAU_01911
symbol: sufS
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.


ensembl_gene_id: PAU_01912
symbol: sufE
gene_biotype: protein_coding
description:
  Cysteine desulfuration protein sufe; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family.


ensembl_gene_id: PAU_01921
symbol: mdtK
gene_biotype: protein_coding
description:
  Multidrug resistance protein mdtk (multidrug-efflux transporter); Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.


ensembl_gene_id: PAU_01927
symbol: purR
gene_biotype: protein_coding
description:
  HTH-type transcriptional repressor PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.


ensembl_gene_id: PAU_01928
symbol: sodB
gene_biotype: protein_coding
description:
  Superoxide dismutase [fe]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: PAU_01930
symbol: grxD
gene_biotype: protein_coding
description:
  Glutaredoxin-4 (grx4) (monothiol glutaredoxin); Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: PAU_01931
symbol: rnt
gene_biotype: protein_coding
description:
  Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: PAU_01932
symbol: gloA
gene_biotype: protein_coding
description:
  Lactoylglutathione lyase (methylglyoxalase) (s-d-lactolyglutathion methylglyoxal lyase); Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: PAU_01936
symbol: anmK
gene_biotype: protein_coding
description:
  anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: PAU_01937
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: PAU_01938
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase 1; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: PAU_01939
symbol: pdxY-2
gene_biotype: protein_coding
description:
  Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.


ensembl_gene_id: PAU_01948
symbol: pspF
gene_biotype: protein_coding
description:
  Psp operon transcriptional activator pspf; The psp operon is induced by a number of stress conditions, including heat shock, ethanol and filamentous phage infection.


ensembl_gene_id: PAU_01949
symbol: pspA
gene_biotype: protein_coding
description:
  Phage shock protein a; pspA appears to maintain the proton motive force under stress conditions that include over expression of certain phage secretins, heat shock, ethanol and protein export defects.


ensembl_gene_id: PAU_01957
symbol: tpx
gene_biotype: protein_coding
description:
  Thiol peroxidase (scavengase p20); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: PAU_01963
symbol: zntB
gene_biotype: protein_coding
description:
  Zinc transport protein zntb; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: PAU_01964
symbol: ydaO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: PAU_01965
symbol: PAU_01965
gene_biotype: protein_coding
description:
  Small multidrug resistance pump; Members of this family which have been characterised, belong to the small multidrug resistance (Smr) protein family and are integral membrane proteins. They confer resistance to a wide range of toxic compounds by removing them for the cells.


ensembl_gene_id: PAU_01967
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulfide bond formation protein b (disulfide oxidoreductase); Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: PAU_01968
symbol: nhaB
gene_biotype: protein_coding
description:
  Na(+)/h(+) antiporter nhab (sodium/proton antiporter nhab); Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: PAU_01971
symbol: dadX
gene_biotype: protein_coding
description:
  Alanine racemase, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: PAU_01972
symbol: yeaF
gene_biotype: protein_coding
description:
  Putative uncharacterized protein yeaf (putative scaffolding protein i the formation of a murein-synthesizing holoenzyme).


ensembl_gene_id: PAU_01974
symbol: gapA
gene_biotype: protein_coding
description:
  Glyceraldehyde-3-phosphate dehydrogenase a (gapdh-a); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: PAU_01982
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]


ensembl_gene_id: PAU_01984
symbol: PAU_01984
gene_biotype: protein_coding
description:
  Similarities with transcription regulator lysr family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_02022
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase (formyl-fh(4) hydrolase); Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: PAU_02024
symbol: hnr
gene_biotype: protein_coding
description:
  Signal transduction response regulator; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.


ensembl_gene_id: PAU_02030
symbol: adhE
gene_biotype: protein_coding
description:
  Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: PAU_02039
symbol: cls
gene_biotype: protein_coding
description:
  Cardiolipin synthetase (cardiolipin synthase) (cl synthase); Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: PAU_02041
symbol: tonB-2
gene_biotype: protein_coding
description:
  Iron ion transmembrane transporter-tonb protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: PAU_02043
symbol: ispZ
gene_biotype: protein_coding
description:
  Probable intracellular septation protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: PAU_02050
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: PAU_02051
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: PAU_02053
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: PAU_02065
symbol: rluB
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: PAU_02075
symbol: cysB
gene_biotype: protein_coding
description:
  Hth-type transcriptional regulator cysb (cys regulon transcriptiona activator); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_02078
symbol: ribA
gene_biotype: protein_coding
description:
  Gtp cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.


ensembl_gene_id: PAU_02080
symbol: yciS
gene_biotype: protein_coding
description:
  Putative inner membrane protein ycis; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: PAU_02081
symbol: yciM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: PAU_02082
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: PAU_02089
symbol: dnt
gene_biotype: protein_coding
description:
  Cytotoxic necrotizing factor proteins alter host cell actin cytoskeleton and promote bacterial invasion of the blood-brain barrier endothelial cells. CNF1 belongs to a unique group of large cytotoxins that cause constitutive activation of Rho guanosine triphosphatases (GTPases), which are key regulators of the actin cytoskeleton.


ensembl_gene_id: PAU_02113
symbol: rnb
gene_biotype: protein_coding
description:
  Exoribonuclease 2; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: PAU_02114
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease iii (dna-(apurinic or apyrimidinic site) lyase); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: PAU_02115
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfe; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: PAU_02116
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfg; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: PAU_02117
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfd; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: PAU_02118
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfc; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: PAU_02119
symbol: rnfB
gene_biotype: protein_coding
description:
  4Fe-4S ferredoxin, iron-sulphur binding; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: PAU_02120
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex protein rnfa; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: PAU_02139
symbol: PAU_02139
gene_biotype: protein_coding
description:
  Death-on-curing protein-(prevent host death phd); Antitoxin component of a type II toxin-antitoxin (TA) system.


ensembl_gene_id: PAU_02155
symbol: add
gene_biotype: protein_coding
description:
  Adenosine deaminase (adenosine aminohydrolase); Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: PAU_02159
symbol: fumC
gene_biotype: protein_coding
description:
  Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.


ensembl_gene_id: PAU_02170
symbol: cbpD
gene_biotype: protein_coding
description:
  Chitin-binding protein cbpd viral capsid; Entomopoxviruses are a class of insect viruses whose virions are embedded in cytoplasmic occlusion bodies. The major component of these protective complexes is a protein called spheroidin/spindolin. Intermolecular disulphide bonds have been shown to play major roles in the formation and structure of these viral occlusion bodies some of which are spindle body proteins.


ensembl_gene_id: PAU_02181
symbol: ynfL
gene_biotype: protein_coding
description:
  Putative transcriptional regulator lysr-type; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_02183
symbol: ynfK
gene_biotype: protein_coding
description:
  Putative dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: PAU_02186
symbol: ydfG
gene_biotype: protein_coding
description:
  Nadp-dependent l-serine/l-allo-threonine dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PAU_02208
symbol: PAU_02208
gene_biotype: protein_coding
description:
  Beta-alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PAU_02230
symbol: PAU_02230
gene_biotype: protein_coding
description:
  Putative insecticidal toxin; Toxin that acts on host cells by modifying Rho proteins by tyrosine GlcNAcylation and heterotrimeric G alpha proteins by deamidation. Catalyzes the mono-O-GlcNAcylation of small GTPases of the Rho family (RhoA, RhoB, RhoC, Rac1, Rac2, Rac3, Cdc42) in eukaryotic host cells at the conserved tyrosine residue located in the switch I region (Tyr-32/34), using UDP-N-acetylglucosamine (UDP-GlcNAc) as the sugar donor; other GTPases of the Rho, Ras or Rab families are not substrates. Tyrosine glycosylation inhibits Rho activation and prevents interaction with downst [...]


ensembl_gene_id: PAU_02264
symbol: pa-1L-2
gene_biotype: protein_coding
description:
  Members of this family are similar to the galactophilic lectin-1 expressed by P. aeruginosa ((PA-IL, ). Lectins recognising specific carbohydrates found on the surface of host cells are known to be involved in the initiation of infections by this organism.


ensembl_gene_id: PAU_02294
symbol: blaA
gene_biotype: protein_coding
description:
  Ctx-m type extended-spectrum beta-lactamase; Beta-lactamase catalyses the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins.


ensembl_gene_id: PAU_02296
symbol: PAU_02296
gene_biotype: protein_coding
description:
  Secreted hemolysin-type calcium-binding bacteriocin, putative; It has been suggested that the internally repeated domain of haemolysin may be involved in Ca-mediated binding to erythrocytes.


ensembl_gene_id: PAU_02353
symbol: mhpB
gene_biotype: protein_coding
description:
  2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.


ensembl_gene_id: PAU_02354
symbol: hcaB
gene_biotype: protein_coding
description:
  2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PAU_02361
symbol: psuG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: PAU_02375
symbol: ureD
gene_biotype: protein_coding
description:
  Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: PAU_02376
symbol: ureG
gene_biotype: protein_coding
description:
  Urease accessory protein ureg; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.


ensembl_gene_id: PAU_02377
symbol: ureF
gene_biotype: protein_coding
description:
  Urease accesory protein uref; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.


ensembl_gene_id: PAU_02397
symbol: pntB
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: PAU_02398
symbol: pntA
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


ensembl_gene_id: PAU_02406
symbol: lpfA
gene_biotype: protein_coding
description:
  Similar to fimbrial subunit type 1; Involved in regulation of length and mediation of adhesion of fimbriae.


ensembl_gene_id: PAU_02407
symbol: lpfB
gene_biotype: protein_coding
description:
  Similar to hypothetical fimbrial chaperone yrai of escherichia coli; Periplasmic chaperones assist pili assembly by binding to the subunits, thereby preventing premature aggregation.


ensembl_gene_id: PAU_02409
symbol: mrkD
gene_biotype: protein_coding
description:
  Similar to fimbria adhesin protein precursor; Involved in regulation of length and mediation of adhesion of fimbriae.


ensembl_gene_id: PAU_02417
symbol: azoR
gene_biotype: protein_coding
description:
  FMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: PAU_02421
symbol: ldhA
gene_biotype: protein_coding
description:
  Fermentative d-lactate dehydrogenase, nad-dependent (fermentative d lactate dehydrogenase); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.


ensembl_gene_id: PAU_02429
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein minc; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: PAU_02431
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: PAU_02432
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease d (rnase d); Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: PAU_02443
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: PAU_02456
symbol: scoT
gene_biotype: protein_coding
description:
  Thioesterase domains often occur integrated in or associated with peptide synthetases which are involved in the non-ribosomal synthesis of peptide antibiotics; thioesterase ii.


ensembl_gene_id: PAU_02464
symbol: msbB
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (kdo)2-(lauroyl)-lipid iva acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: PAU_02467
symbol: znuC
gene_biotype: protein_coding
description:
  Putative zinc import ATP-binding component of ABC transporter; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: PAU_02469
symbol: ruvB
gene_biotype: protein_coding
description:
  RuvB protein, holliday junction helicase subunit A; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: PAU_02470
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: PAU_02471
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: PAU_02474
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: PAU_02476
symbol: cmoA
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: PAU_02477
symbol: yecP
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: PAU_02478
symbol: cutC
gene_biotype: protein_coding
description:
  Copper homeostasis protein cutc; Participates in the control of copper homeostasis. Belongs to the CutC family.


ensembl_gene_id: PAU_02485
symbol: PAU_02485
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; This repeat composes the C-terminal part of the bacteriophage T4 baseplate protein Gp5. This region of the protein forms a needle like projection from the baseplate that is presumed to puncture the bacterial cell membrane.


ensembl_gene_id: PAU_02502
symbol: mviN
gene_biotype: protein_coding
description:
  Virulence factor mvin homolog; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: PAU_02503
symbol: rimJ
gene_biotype: protein_coding
description:
  [ribosomal protein S5]-alanine N-acetyltransferase; Ribosomal-protein-alanine acetyltransferase (acetylating enzyme for n terminal of ribosomal protein s5).


ensembl_gene_id: PAU_02504
symbol: mdtH
gene_biotype: protein_coding
description:
  Multidrug resistance protein - MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients.


ensembl_gene_id: PAU_02507
symbol: ycdW
gene_biotype: protein_coding
description:
  Similar to probable 2-hydroxyacid dehydrogenase ycdw of escherichi coli; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.


ensembl_gene_id: PAU_02510
symbol: luxE
gene_biotype: protein_coding
description:
  LuxE is an acyl-protein synthetase found in bioluminescent bacteria. LuxE catalyses the formation of an acyl-protein thiolester from a fatty acid and a protein. This is the second step in the bioluminescent fatty acid reduction system, which converts tetradecanoic acid to the aldehyde substrate of the luciferase-catalysed bioluminescence reaction.


ensembl_gene_id: PAU_02512
symbol: luxA
gene_biotype: protein_coding
description:
  Luciferase; The enzyme responsible for bioluminescence in motile Gram-negative luminous bacteria is bacterial luciferase, which catalyses the oxidation of reduced riboflavin phosphate (FMNH2) and a long chain fatty aldehyde with the emission of blue green light (490 nm).


ensembl_gene_id: PAU_02513
symbol: luxD
gene_biotype: protein_coding
description:
  Acyl transferase; Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction; Belongs to the LuxD family.


ensembl_gene_id: PAU_02514
symbol: luxC
gene_biotype: protein_coding
description:
  acyl-CoA reductase; LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.


ensembl_gene_id: PAU_02524
symbol: hemK
gene_biotype: protein_coding
description:
  Protein methyltranferase hemk (protein-glutamine n methyltransferase); Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: PAU_02525
symbol: prfA
gene_biotype: protein_coding
description:
  Peptide chain release factor rf-1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: PAU_02526
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: PAU_02527
symbol: lolB
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein lolb precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: PAU_02528
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-c-methyl-d-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily.


ensembl_gene_id: PAU_02529
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: PAU_02531
symbol: PAU_02531
gene_biotype: protein_coding
description:
  Similar to putative invasin and adhesin; Intimin is a bacterial cell-adhesion molecule that mediates the intimate bacterial host-cell interaction.


ensembl_gene_id: PAU_02538
symbol: eaeH
gene_biotype: protein_coding
description:
  Putative adhesin; Bacterial adhesion mediation molecule intimin targets the translocated intimin receptor, Tir. Tir is secreted by the bacteria and is embedded in the target cell's plasma membrane. This facilitates bacterial cell attachment to the host.


ensembl_gene_id: PAU_02541
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: PAU_02542
symbol: ychF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: PAU_02551
symbol: sypC3
gene_biotype: protein_coding
description:
  Similar to different toxins like syringomycin synthetase an gramicidin s synthase 2; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: PAU_02555
symbol: PAU_02555
gene_biotype: protein_coding
description:
  Putative short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PAU_02561
symbol: aqpZ
gene_biotype: protein_coding
description:
  Aquaporin z; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: PAU_02567
symbol: uvrC
gene_biotype: protein_coding
description:
  Uvrabc system protein c (protein uvrc) (excinuclease abc subunit c); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: PAU_02568
symbol: pgsA
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphate synthetase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PAU_02581
symbol: php
gene_biotype: protein_coding
description:
  Phosphotriesterase homology protein; Bacteria such as harbor a plasmid that carries the gene for Aryldialkylphosphatase (). This enzyme has attracted interest because of its potential use in the detoxification of chemical waste and warfare agents and its ability to degrade agricultural pesticides such as parathion.


ensembl_gene_id: PAU_02600
symbol: dsdC
gene_biotype: protein_coding
description:
  D-serine dehydratase (deaminase) transcriptional activator dsdc; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_02604
symbol: wrbA
gene_biotype: protein_coding
description:
  Flavoprotein wrba (trp repressor-binding protein); Flavodoxins are electron-transfer proteins that function in various electron transport systems. They bind one FMN molecule, which serves as a redox-active prosthetic group and are functionally interchangeable with ferredoxins.


ensembl_gene_id: PAU_02605
symbol: putP
gene_biotype: protein_coding
description:
  Sodium/proline symporter (proline permease); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PAU_02606
symbol: putA
gene_biotype: protein_coding
description:
  Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family.  In the N-terminal section; belongs to the proline dehydrogenase family.


ensembl_gene_id: PAU_02608
symbol: fliA
gene_biotype: protein_coding
description:
  Rna polymerase sigma factor for flagellar operon (sigma-f factor (sigma-27) (sigma-28); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: PAU_02609
symbol: fliC
gene_biotype: protein_coding
description:
  Flagellin (flic); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: PAU_02610
symbol: fliD
gene_biotype: protein_coding
description:
  Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: PAU_02615
symbol: fliF
gene_biotype: protein_coding
description:
  Flagellar basal-body m-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: PAU_02616
symbol: fliG
gene_biotype: protein_coding
description:
  Flagellar motor switch protein flig; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: PAU_02619
symbol: fliJ
gene_biotype: protein_coding
description:
  Flagellar flij protein; Flagellar protein that affects chemotactic events. Belongs to the FliJ family.


ensembl_gene_id: PAU_02621
symbol: fliL
gene_biotype: protein_coding
description:
  Flagellar flil protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: PAU_02622
symbol: fliM
gene_biotype: protein_coding
description:
  Flagellar motor switch protein flim; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: PAU_02623
symbol: fliN
gene_biotype: protein_coding
description:
  Flagellar motor switch protein flin; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: PAU_02625
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein flip precursor; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: PAU_02626
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein fliq; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: PAU_02627
symbol: fliR
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein flir; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: PAU_02643
symbol: flgJ
gene_biotype: protein_coding
description:
  Peptidoglycan hydrolase; The N-terminal region of this protein acts directly in flagellar rod assembly, while the C-terminal region is a flagellum-specific muramidase (peptidoglycan hydrolase) required for formation of the outer membrane L ring.


ensembl_gene_id: PAU_02644
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar p-ring protein precursor (basal body p-ring protein); Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: PAU_02645
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar l-ring protein precursor (basal body l-ring protein); Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: PAU_02649
symbol: flgD
gene_biotype: protein_coding
description:
  Basal-body rod modification protein flgd (flagellar protein for th initiation of hook assembly); Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: PAU_02650
symbol: flgC
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein flgc (putative proximal rod protein); Flagellar basal-body rod; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: PAU_02651
symbol: flgB
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein flgb (putative proximal rod protein); Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: PAU_02652
symbol: flgA
gene_biotype: protein_coding
description:
  Flagella basal body p-ring formation protein flga; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: PAU_02665
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein flha; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: PAU_02666
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein flhb; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: PAU_02671
symbol: PAU_02671
gene_biotype: protein_coding
description:
  Beta-ketoacyl synthase:phosphopantetheine binding; Involved in the biosynthesis of a polyketide antibiotic; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: PAU_02677
symbol: PAU_02677
gene_biotype: protein_coding
description:
  Similar to tetracycline-efflux transporter; The region plays an important role in metal-tetracycline transport; it perhaps acts as a gate that opens on the charge-charge interaction between Asp66 and the metal-tetracycline.


ensembl_gene_id: PAU_02678
symbol: acmB
gene_biotype: protein_coding
description:
  Similar to antibiotic synthetase; This domain is found in many multi-domain enzymes which synthesize peptide antibiotics.


ensembl_gene_id: PAU_02680
symbol: cheZ
gene_biotype: protein_coding
description:
  Chemotaxis protein chez; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: PAU_02682
symbol: cheB
gene_biotype: protein_coding
description:
  Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: PAU_02683
symbol: cheR
gene_biotype: protein_coding
description:
  Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: PAU_02689
symbol: motA
gene_biotype: protein_coding
description:
  The bacterial protein motA is required for the rotation of the flagellar motor. This protein probably forms a transmembrane proton channel used to energize the flagellar rotary motor.


ensembl_gene_id: PAU_02690
symbol: flhC
gene_biotype: protein_coding
description:
  Flagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: PAU_02691
symbol: flhD
gene_biotype: protein_coding
description:
  Transcriptional activator flhd; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: PAU_02695
symbol: cspC-2
gene_biotype: protein_coding
description:
  Cold shock-like protein cspc (csp-c); 'cold shock' proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature.


ensembl_gene_id: PAU_02703
symbol: htrB
gene_biotype: protein_coding
description:
  Lipid a biosynthesis lauroyl acyltransferase (heat shock protein b); Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: PAU_02722
symbol: cas1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


ensembl_gene_id: PAU_02733
symbol: yccV
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.


ensembl_gene_id: PAU_02743
symbol: sulA
gene_biotype: protein_coding
description:
  Cell division inhibitor sula; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: PAU_02744
symbol: ompA
gene_biotype: protein_coding
description:
  Outer membrane protein a (outer membrane protein ii*); Belongs to the outer membrane OOP (TC 1.B.6) superfamily.


ensembl_gene_id: PAU_02745
symbol: ycbG
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.


ensembl_gene_id: PAU_02747
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: PAU_02753
symbol: ycbY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: PAU_02758
symbol: zapC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: PAU_02759
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: PAU_02762
symbol: pncB
gene_biotype: protein_coding
description:
  Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: PAU_02776
symbol: bfpE
gene_biotype: protein_coding
description:
  Similar to type II secretion system; Involved in a general secretion pathway (GSP) for the export of proteins (also called the type II pathway), have been found to be evolutionary related. These are proteins of about 400 amino acids that are highly hydrophobic and which are thought to be integral protein of the inner membrane.


ensembl_gene_id: PAU_02780
symbol: pilN
gene_biotype: protein_coding
description:
  Piln (lipoprotein); Outer membrane pore proteins for type II secretion, type III secretion, and type IV pilus formation. Proteins in this entry appear to be secretins for pilus formation, although they are quite different from PilQ. Members include the PilN lipoprotein of the plasmid R64 thin pilus, a type IV pilus.


ensembl_gene_id: PAU_02785
symbol: pppA
gene_biotype: protein_coding
description:
  Type 4 prepilin-like proteins leader peptide-processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: PAU_02786
symbol: PAU_02786
gene_biotype: protein_coding
description:
  Similar to type iv prepilin. putative secreted protein; Most often found at the N-terminus of pilins and other proteins involved in secretion.


ensembl_gene_id: PAU_02811
symbol: mukB
gene_biotype: protein_coding
description:
  Chromosome partition protein mukb (structural maintenance o chromosome-related protein); Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.


ensembl_gene_id: PAU_02812
symbol: mukE
gene_biotype: protein_coding
description:
  Chromosome partition protein muke; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.


ensembl_gene_id: PAU_02813
symbol: mukF
gene_biotype: protein_coding
description:
  Ca2+-binding protein involved in chromosome partitioning; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.


ensembl_gene_id: PAU_02814
symbol: smtA
gene_biotype: protein_coding
description:
  S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: PAU_02816
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: PAU_02818
symbol: lpxK
gene_biotype: protein_coding
description:
  Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: PAU_02819
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid a export atp-binding/permease protein msba; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: PAU_02823
symbol: imm2
gene_biotype: protein_coding
description:
  This family includes bacterial colicin and pyocin immunity proteins. These immunity proteins can bind specifically to the DNase-type colicins and pyocins and inhibit their bactericidal activity.


ensembl_gene_id: PAU_02824
symbol: PAU_02824
gene_biotype: protein_coding
description:
  Putative pyocin-like protein; Pyocins cause breakdown of chromosomal DNA and complete inhibition of lipid synthesis in sensitive cells.


ensembl_gene_id: PAU_02826
symbol: PAU_02826
gene_biotype: protein_coding
description:
  Putative pyocin-like protein; Similar to pyocin s2 and s1; Similar to central portion of Escherichia coli O6:K15:H31 (strain 536/UPEC) putative colicin. UniProt:Q0TLM8 (EMBL:CP000247) (593 aa) fasta scores: E()=0.0037, 51.923 38d in 52 aa, and to central portion of Photorhabdus luminescens subsp. laumondii similar to pyocin s2 and s1. UniProt:Q7N5Q1 (EMBL:BX571865) (562 aa) fasta scores: E()=8.1e-29, 72.174 38d in 115 aa.


ensembl_gene_id: PAU_02827
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor beta-subunit (ihf-beta); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: PAU_02828
symbol: rpsA
gene_biotype: protein_coding
description:
  30s ribosomal protein s1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: PAU_02830
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: PAU_02831
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: PAU_02834
symbol: ansB
gene_biotype: protein_coding
description:
  L-asparaginase ii (l-asparagine amidohydrolase ii) (l-asnase ii (colaspase); Belongs to the asparaginase 1 family.


ensembl_gene_id: PAU_02838
symbol: pflA
gene_biotype: protein_coding
description:
  Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: PAU_02841
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: PAU_02843
symbol: lolA
gene_biotype: protein_coding
description:
  Outer-membrane lipoprotein carrier protein precursor (p20); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: PAU_02849
symbol: aat
gene_biotype: protein_coding
description:
  leucyl/phenylalanyl-tRNA--protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: PAU_02850
symbol: infA
gene_biotype: protein_coding
description:
  Protein chain initiation factor if-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: PAU_02852
symbol: clpS
gene_biotype: protein_coding
description:
  Atp-dependent clp protease adaptor protein clps; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: PAU_02854
symbol: macB-2
gene_biotype: protein_coding
description:
  Macrolide-specific abc-type efflux carrier protein macb; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: PAU_02855
symbol: macA
gene_biotype: protein_coding
description:
  Macrolide-specific efflux protein maca; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: PAU_02861
symbol: rumB
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.


ensembl_gene_id: PAU_02862
symbol: ybjN
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Similar to putative sensory transduction regulator ybjn of escherichi coli.


ensembl_gene_id: PAU_02870
symbol: dacC
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6); Present in the penicillin-binding protein family of beta-lactamases, which constitute the most common bacterial resistance mechanism against beta-lactam antibiotics. Beta-lactamases appear to have evolved from DD-transpeptidases, which are penicillin-binding proteins involved in cell wall biosynthesis, and as such are one of the main targets of beta-lactam antibiotics.


ensembl_gene_id: PAU_02873
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.


ensembl_gene_id: PAU_02874
symbol: hisCD
gene_biotype: protein_coding
description:
  Putative histidine biosynthesis bifunctional protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: PAU_02875
symbol: hisCD-2
gene_biotype: protein_coding
description:
  Putative histidine biosynthesis bifunctional protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: PAU_02876
symbol: hisB
gene_biotype: protein_coding
description:
  Histidine biosynthesis bifunctional protein; In the N-terminal section; belongs to the histidinol- phosphatase family.


ensembl_gene_id: PAU_02877
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: PAU_02879
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: PAU_02880
symbol: hisI
gene_biotype: protein_coding
description:
  Histidine biosynthesis bifunctional protein; In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: PAU_02885
symbol: gnd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: PAU_02891
symbol: mrp
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: PAU_02892
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: PAU_02895
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: PAU_02902
symbol: moeA
gene_biotype: protein_coding
description:
  Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: PAU_02913
symbol: dps
gene_biotype: protein_coding
description:
  Stationary phase nucleoid protein; Dps is a DNA-binding protein, synthesized during prolonged starvation, that seems to protect DNA from oxidative damage.


ensembl_gene_id: PAU_02915
symbol: dinG
gene_biotype: protein_coding
description:
  Probable atp-dependent helicase (dna-damage-inducible protein g); DNA-dependent ATPase and 5'-3' DNA helicase.


ensembl_gene_id: PAU_02921
symbol: dusC
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase C; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: PAU_02922
symbol: rhlE
gene_biotype: protein_coding
description:
  Putative atp-dependent rna helicase rhle; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: PAU_02933
symbol: moaC
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein c; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: PAU_02934
symbol: moaA
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein a; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: PAU_02935
symbol: ybhK
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: PAU_02936
symbol: uvrB
gene_biotype: protein_coding
description:
  Uvrabc system protein b (protein uvrb) (excinuclease abc subunit b); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesi [...]


ensembl_gene_id: PAU_02937
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: PAU_02938
symbol: bioC
gene_biotype: protein_coding
description:
  Biotin biosynthesis; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: PAU_02939
symbol: bioF
gene_biotype: protein_coding
description:
  7-keto-8-amino pelargonic acid synthetase (8-amino-7-oxononanoat synthase); Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.


ensembl_gene_id: PAU_02940
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthetase (biotin synthase); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: PAU_02941
symbol: bioA
gene_biotype: protein_coding
description:
  7,8-diaminopelargonic acid synthetase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: PAU_02942
symbol: pgl
gene_biotype: protein_coding
description:
  6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.


ensembl_gene_id: PAU_02944
symbol: modC
gene_biotype: protein_coding
description:
  Molybdenum import ATP-binding protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: PAU_02945
symbol: modB
gene_biotype: protein_coding
description:
  Molybdenum transport system permease protein modb; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: PAU_02950
symbol: gpmA
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: PAU_02951
symbol: aroG
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase, phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: PAU_02953
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase a; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: PAU_02957
symbol: ybgF
gene_biotype: protein_coding
description:
  tRNA-Lys; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: PAU_02958
symbol: pal
gene_biotype: protein_coding
description:
  Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: PAU_02959
symbol: tolB
gene_biotype: protein_coding
description:
  Periplasmic protein involved in the tonb-independent uptake of group colicins; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.


ensembl_gene_id: PAU_02961
symbol: tolR
gene_biotype: protein_coding
description:
  Tolr protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: PAU_02962
symbol: tolQ
gene_biotype: protein_coding
description:
  Tolq protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: PAU_02971
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: PAU_02972
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: PAU_02973
symbol: sucB
gene_biotype: protein_coding
description:
  Dihydrolipoamide succinyltransferase component of 2-oxoglutarat dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: PAU_02975
symbol: sdhB
gene_biotype: protein_coding
description:
  Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: PAU_02976
symbol: sdhA
gene_biotype: protein_coding
description:
  Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: PAU_02977
symbol: sdhD
gene_biotype: protein_coding
description:
  Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).


ensembl_gene_id: PAU_02983
symbol: PAU_02983
gene_biotype: protein_coding
description:
  Chitinases of family 19 (also known as classes IA or I and IB or II) are enzymes from plants that function in the defense against fungal and insect pathogens by destroying their chitin-containing cell wall.


ensembl_gene_id: PAU_02986
symbol: kdpA
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: PAU_02987
symbol: kdpB
gene_biotype: protein_coding
description:
  Potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: PAU_02988
symbol: kdpC
gene_biotype: protein_coding
description:
  Potassium-transporting atpase c chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: PAU_02995
symbol: seqA
gene_biotype: protein_coding
description:
  Seqa protein, negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: PAU_03009
symbol: api89-2
gene_biotype: protein_coding
description:
  Putative membrane-bound sugar-binding protein; Contains RHS domain and YD repeats.These repeats appear in general to be involved in binding carbohydrate.


ensembl_gene_id: PAU_03012
symbol: dctA
gene_biotype: protein_coding
description:
  C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PAU_03014
symbol: PAU_03014
gene_biotype: protein_coding
description:
  Putative membrane protein; Photorhabdus luminescens subsp. laumondii complete genome; segment 11/17.


ensembl_gene_id: PAU_03020
symbol: amiF
gene_biotype: protein_coding
description:
  Formamidase; Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.


ensembl_gene_id: PAU_03021
symbol: PAU_03021
gene_biotype: protein_coding
description:
  Putative hemagglutinin/hemolysin pala; A number of the members of this family have been designated adhesins, filamentous haemagglutinins, heme/hemopexin-binding protein.


ensembl_gene_id: PAU_03023
symbol: PAU_03023
gene_biotype: protein_coding
description:
  Similar to hemagglutinin-like secreted protein. putative secrete protein; This highly divergent repeat occurs in number of proteins implicated in cell aggregation.


ensembl_gene_id: PAU_03026
symbol: PAU_03026
gene_biotype: protein_coding
description:
  Similar to hemagglutinin/hemolysin-related proteins. putativ transmembrane protein; This highly divergent repeat occurs in number of proteins implicated in cell aggregation.


ensembl_gene_id: PAU_03027
symbol: rtxA
gene_biotype: protein_coding
description:
  The RTX (repeats in toxin) family of cytolytic toxins belong to the Type I secretion system, and are important virulence factors in Gram-negative bacteria.


ensembl_gene_id: PAU_03071
symbol: doc
gene_biotype: protein_coding
description:
  Part of a two protein operon with prevents-host-death (phd) that forms an addiction module. DOC lacks homology to analogous addiction module post-segregational killing proteins involved in plasmid maintenance. These modules work as a combination of a long lived poison (e.g. this protein) and a more abundant but shorter lived antidote.


ensembl_gene_id: PAU_03079
symbol: PAU_03079
gene_biotype: protein_coding
description:
  Toxin secretion abc transporter protein, hlyb family; similar to unknown protein vc1446 of vibrio cholerae.


ensembl_gene_id: PAU_03082
symbol: fldA
gene_biotype: protein_coding
description:
  Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: PAU_03089
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: PAU_03124
symbol: gene0070
gene_biotype: protein_coding
description:
  Antiterminator proteins control gene expression by recognising control signals near the promoter and preventing transcriptional termination which would otherwise occur at sites that may be a long way downstream.


ensembl_gene_id: PAU_03145
symbol: miaB
gene_biotype: protein_coding
description:
  Trna-methylthiotransferase miab protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: PAU_03147
symbol: ybeY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: PAU_03149
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: PAU_03150
symbol: PAU_03150
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: PAU_03157
symbol: rlpB
gene_biotype: protein_coding
description:
  Rare lipoprotein b precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: PAU_03159
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: PAU_03160
symbol: rsfS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: PAU_03161
symbol: rlmH
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: PAU_03162
symbol: pbpA
gene_biotype: protein_coding
description:
  Cell elongation, e phase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: PAU_03163
symbol: rodA
gene_biotype: protein_coding
description:
  Rod shape-determining protein roda; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: PAU_03164
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein a; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: PAU_03165
symbol: dacA
gene_biotype: protein_coding
description:
  Penicillin-binding protein 5 functions as a D-alanyl-D-alanine carboxypeptidase. Its precise function is unknown; it may mediate interactions with other cell wall-synthesising enzymes, thus allowing the protein to be recruited to areas of active cell wall synthesis. It may also function as a linker domain that positions the active site in the catalytic domain closer to the peptidoglycan layer, to allow it to interact with cell wall peptides.


ensembl_gene_id: PAU_03167
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: PAU_03168
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: PAU_03169
symbol: crcB
gene_biotype: protein_coding
description:
  Inner membrane protein crcb homolog; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: PAU_03171
symbol: ogt
gene_biotype: protein_coding
description:
  Methylated-dna--protein-cysteine s-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: PAU_03174
symbol: nrdE
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase alpha-chain (ribonucleotid reductase r1 subunit); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: PAU_03175
symbol: nrdF
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase 2 beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.


ensembl_gene_id: PAU_03177
symbol: proV
gene_biotype: protein_coding
description:
  Glycine betaine/l-proline transport atp-binding protein prov; Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits this transport system to accumulate glycine betaine and other solutes which offer osmo-protection.


ensembl_gene_id: PAU_03178
symbol: proW
gene_biotype: protein_coding
description:
  Glycine betaine/l-proline transport system permease protein prow; Bacterial binding protein-dependent transport systems, are multicomponent systems typically composed of a periplasmic substrate-binding protein, one or two reciprocally homologous integral inner-membrane proteins and one or two peripheral membrane ATP-binding proteins that couple energy to the active transport system. The integral inner-membrane proteins translocate the substrate across the membrane.


ensembl_gene_id: PAU_03184
symbol: emrA
gene_biotype: protein_coding
description:
  Multidrug resistance secretion protein; emrA and emrB confer resistance to carbonylcyanide m-chlorophenylhydrazone, nalidixic acid, and a number of other toxic compounds.


ensembl_gene_id: PAU_03185
symbol: emrB
gene_biotype: protein_coding
description:
  emrA and emrB confer resistance to carbonylcyanide m-chlorophenylhydrazone, nalidixic acid, and a number of other toxic compounds; Belongs to the major facilitator superfamily.


ensembl_gene_id: PAU_03186
symbol: yfiF
gene_biotype: protein_coding
description:
  Similar to putative trna/rrna methyltransferase yfif escherichia coli; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: PAU_03190
symbol: clpB
gene_biotype: protein_coding
description:
  Chaperone clpb; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: PAU_03192
symbol: rluD
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: PAU_03193
symbol: yfiO
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.


ensembl_gene_id: PAU_03199
symbol: aroF
gene_biotype: protein_coding
description:
  Phospho-2-dehydro-3-deoxyheptonate aldolase, tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: PAU_03201
symbol: rplS
gene_biotype: protein_coding
description:
  50s ribosomal protein l19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: PAU_03202
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: PAU_03203
symbol: rimM
gene_biotype: protein_coding
description:
  16s rrna processing protein rimm; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: PAU_03205
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle protein (fifty-four homolog); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into th [...]


ensembl_gene_id: PAU_03208
symbol: luxS
gene_biotype: protein_coding
description:
  S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: PAU_03209
symbol: gshA
gene_biotype: protein_coding
description:
  Glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: PAU_03210
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: PAU_03211
symbol: alaS
gene_biotype: protein_coding
description:
  Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: PAU_03212
symbol: recA
gene_biotype: protein_coding
description:
  Protein recA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: PAU_03214
symbol: lplT
gene_biotype: protein_coding
description:
  Similar to unknown protein YgeD of Escherichia; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.


ensembl_gene_id: PAU_03215
symbol: aas
gene_biotype: protein_coding
description:
  AAS bifunctional protein; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: PAU_03216
symbol: aroL
gene_biotype: protein_coding
description:
  Shikimate kinase 2; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.


ensembl_gene_id: PAU_03217
symbol: proA
gene_biotype: protein_coding
description:
  Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: PAU_03218
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: PAU_03220
symbol: gpt
gene_biotype: protein_coding
description:
  Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.


ensembl_gene_id: PAU_03222
symbol: dinB
gene_biotype: protein_coding
description:
  DNA polymerase IV (DNA-damage-inducible protein P); Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: PAU_03251
symbol: PAU_03251
gene_biotype: protein_coding
description:
  Thiamine biosynthesis lipoprotein ApbE; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: PAU_03252
symbol: nqrF
gene_biotype: protein_coding
description:
  Na+-translocating NADH-ubiquinone oxidoreductase, beta chain; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: PAU_03253
symbol: nqrE
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase, chain E (Na-NQR complex subunit 5); NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: PAU_03254
symbol: nqrD
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase, chain D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: PAU_03255
symbol: nqrC
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase, chain C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: PAU_03256
symbol: nqrB
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase, chain B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: PAU_03257
symbol: nqrA
gene_biotype: protein_coding
description:
  Na(+)-translocating NADH-quinone reductase, chain A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: PAU_03260
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: PAU_03269
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: PAU_03275
symbol: PAU_03275
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: PAU_03278
symbol: yqgF
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: PAU_03280
symbol: PAU_03280
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.


ensembl_gene_id: PAU_03281
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: PAU_03283
symbol: PAU_03283
gene_biotype: protein_coding
description:
  yggV HAM1-like protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: PAU_03284
symbol: PAU_03284
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: PAU_03290
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.


ensembl_gene_id: PAU_03292
symbol: PAU_03292
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.


ensembl_gene_id: PAU_03293
symbol: mltC
gene_biotype: protein_coding
description:
  Membrane-bound lytic murein transglycosylase C precursor; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: PAU_03382
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: PAU_03383
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: PAU_03386
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: PAU_03387
symbol: PAU_03387
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: PAU_03388
symbol: dnaX
gene_biotype: protein_coding
description:
  DNA polymerase III subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: PAU_03389
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: PAU_03410
symbol: queC
gene_biotype: protein_coding
description:
  Queuosine biosynthesis protein queC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: PAU_03414
symbol: PAU_03414
gene_biotype: protein_coding
description:
  DNA-binding protein HU-beta (NS1) (HU-1); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: PAU_03415
symbol: lon
gene_biotype: protein_coding
description:
  ATP-dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: PAU_03416
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: PAU_03417
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent proteolytic subunit of clpA-ClpP serine protease, heat shock protein F21.5; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: PAU_03422
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: PAU_03427
symbol: PAU_03427
gene_biotype: protein_coding
description:
  Ubiquinol oxidase polypeptide II (Cytochrome O subunit 2) (Oxidase BO(3) subunit 2) (Cytochrome O ubiquinol oxidase subunit 2) (Ubiquinol oxidase chain B).


ensembl_gene_id: PAU_03428
symbol: PAU_03428
gene_biotype: protein_coding
description:
  Ubiquinol oxidase polypeptide I (Cytochrome O subunit 1) (Oxidase BO(3) subunit 1) (Cytochrome O ubiquinol oxidase subunit 1) (Ubiquinol oxidase chain A); Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: PAU_03431
symbol: cyoE
gene_biotype: protein_coding
description:
  cyoE; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: PAU_03434
symbol: PAU_03434
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase (Ketopantoate reductase) (KPA reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: PAU_03436
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: PAU_03437
symbol: xseB
gene_biotype: protein_coding
description:
  Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: PAU_03438
symbol: PAU_03438
gene_biotype: protein_coding
description:
  Geranyltranstransferase (Farnesyl-diphosphate synthase) FPP synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PAU_03439
symbol: dxs
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: PAU_03480
symbol: PAU_03480
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: PAU_03481
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase (Thiamine-phosphate kinase); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: PAU_03482
symbol: nusB
gene_biotype: protein_coding
description:
  N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: PAU_03483
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: PAU_03484
symbol: PAU_03484
gene_biotype: protein_coding
description:
  Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: PAU_03485
symbol: nrdR
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: PAU_03487
symbol: secF
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: PAU_03488
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: PAU_03489
symbol: yajC
gene_biotype: protein_coding
description:
  Hypothetical protein yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: PAU_03490
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]


ensembl_gene_id: PAU_03491
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: PAU_03492
symbol: acpH
gene_biotype: protein_coding
description:
  Acyl carrier protein phosphodiesterase; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family.


ensembl_gene_id: PAU_03500
symbol: PAU_03500
gene_biotype: protein_coding
description:
  Branched chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: PAU_03501
symbol: phoR
gene_biotype: protein_coding
description:
  Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR; Positive and negative sensor protein for pho regulon (positive an negative sensor protein for pho regulon phor).


ensembl_gene_id: PAU_03503
symbol: sbcD
gene_biotype: protein_coding
description:
  Nuclease sbccd subunit d; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: PAU_03508
symbol: rdgC
gene_biotype: protein_coding
description:
  Recombination-associated protein rdgc; May be involved in recombination; Belongs to the RdgC family.


ensembl_gene_id: PAU_03510
symbol: fdp1
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; The Fic (filamentation induced by cAMP) protein is involved in the synthesis of PAB or folate. It would appear that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism and in these organisims cell division could be controlled by coordination of cAMP, Fic and Fts proteins.


ensembl_gene_id: PAU_03524
symbol: sufI
gene_biotype: protein_coding
description:
  Suppressor of ftsi; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.


ensembl_gene_id: PAU_03525
symbol: plsC
gene_biotype: protein_coding
description:
  1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: PAU_03526
symbol: parC
gene_biotype: protein_coding
description:
  Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: PAU_03527
symbol: parE
gene_biotype: protein_coding
description:
  Topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: PAU_03529
symbol: icc
gene_biotype: protein_coding
description:
  Icc protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: PAU_03531
symbol: tolC
gene_biotype: protein_coding
description:
  TolC outer membrane protein, which is required for proper expression of outer membrane protein genes.


ensembl_gene_id: PAU_03536
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase (dhbp synthase); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: PAU_03547
symbol: hldE
gene_biotype: protein_coding
description:
  Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: PAU_03548
symbol: glnE
gene_biotype: protein_coding
description:
  Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]


ensembl_gene_id: PAU_03550
symbol: nfsA
gene_biotype: protein_coding
description:
  Subunit of oxygen-insensitive NADPH nitroreductase; Belongs to the flavin oxidoreductase frp family.


ensembl_gene_id: PAU_03552
symbol: cca
gene_biotype: protein_coding
description:
  Multifunctional cca protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: PAU_03553
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: PAU_03554
symbol: folB
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase (dhna); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: PAU_03555
symbol: ygiH
gene_biotype: protein_coding
description:
  Upf0078 membrane protein ygih; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: PAU_03556
symbol: gcp
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase (glycoprotease); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: PAU_03558
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: PAU_03559
symbol: rpoD
gene_biotype: protein_coding
description:
  Rna polymerase, sigma(70) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: PAU_03622
symbol: idi2
gene_biotype: protein_coding
description:
  Isopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).


ensembl_gene_id: PAU_03626
symbol: ygjU
gene_biotype: protein_coding
description:
  Inner membrane symporter ygju; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: PAU_03627
symbol: alx
gene_biotype: protein_coding
description:
  Protein alx; This family contains a number of integral membrane proteins including the TerC protein. TerC has been implicated in resistance to tellurium, and may be involved in efflux of tellurium ions.


ensembl_gene_id: PAU_03634
symbol: yhaJ
gene_biotype: protein_coding
description:
  Similar to lysr-type transcriptional regulator yhaj of escherichi coli; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_03637
symbol: rsmI
gene_biotype: protein_coding
description:
  Conserved hypothetical Protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: PAU_03642
symbol: mtgA
gene_biotype: protein_coding
description:
  Biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: PAU_03643
symbol: elbB
gene_biotype: protein_coding
description:
  Enhancing lycopene biosynthesis protein 2 (sigma cross-reactin protein 27a) (scrp-27a); Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: PAU_03647
symbol: gltB
gene_biotype: protein_coding
description:
  Glutamate synthase [nadph] large chain (glutamate synthase alph subunit) (nadph-gogat) (glts alpha chain).


ensembl_gene_id: PAU_03648
symbol: gltD
gene_biotype: protein_coding
description:
  Glutamate synthase [nadph] small chain (glutamate synthase bet subunit) (nadph-gogat) (glts beta chain).


ensembl_gene_id: PAU_03650
symbol: sspB
gene_biotype: protein_coding
description:
  Stringent starvation protein b; SspB is encoded in an operon whose synthesis is stimulated by carbon, amino acid, and phosphate starvation.


ensembl_gene_id: PAU_03653
symbol: rplM
gene_biotype: protein_coding
description:
  50s ribosomal protein l13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: PAU_03665
symbol: murA-2
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: PAU_03675
symbol: kdsC
gene_biotype: protein_coding
description:
  3-deoxy-d-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: PAU_03676
symbol: lptC
gene_biotype: protein_coding
description:
  Hypothetical Protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: PAU_03677
symbol: yhbN
gene_biotype: protein_coding
description:
  Protein yhbn precursor probable transporter; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: PAU_03679
symbol: rpoN
gene_biotype: protein_coding
description:
  Rna polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: PAU_03682
symbol: rapZ
gene_biotype: protein_coding
description:
  Conserved hypothetical Protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.


ensembl_gene_id: PAU_03684
symbol: rnk
gene_biotype: protein_coding
description:
  Regulator of nucleoside diphosphate kinase; May act as an anti-Gre factor; Belongs to the Rnk family.


ensembl_gene_id: PAU_03692
symbol: pmbA
gene_biotype: protein_coding
description:
  PmbA facilitates the secretion of microcin B17 (MccB17) the by completing its maturation. Microcin B17 (MccB17) is a peptide antibiotic produced by E. coli strains harbouring plasmid pMccB17.


ensembl_gene_id: PAU_03696
symbol: tldD
gene_biotype: protein_coding
description:
  Tldd protein, suppresses the inhibitory activity of the carbon storage regulator (csra); This group of peptidases belong to MEROPS peptidase family U62 (clan U-). The type example is microcin-processing peptidase 1 from Escherichia coli, which is the product of the gene PmbA. It has been suggests that the pmbA gene product acts to inhibit the interaction between the letD protein and the A subunit of DNA gyrase. The letA (ccdA) and letD (ccdB) genes of the F plasmid, located just outside the sequence essential for F-plasmid replication, contribute to stable maintenance of the plasmid in [...]


ensembl_gene_id: PAU_03700
symbol: yhdE
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: PAU_03701
symbol: mreD
gene_biotype: protein_coding
description:
  Rod shape-determining protein mred; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: PAU_03703
symbol: mreB
gene_biotype: protein_coding
description:
  Rod shape-determining protein mreb; The gene products localise close to the cell surface, forming filamentous helical structures. Many homologues have been found in diverse bacterial groups, suggesting a common ancestor. The crystal structure of MreB from Thermotoga maritima has been resolved using X-ray crystallography. It consists of 19 beta-strands and 15 alpha- helices, and shows remarkable structural similarity to eukaryotic actin. MreB crystals also contain proto-filaments, with individual proteins assembling into polymers like F-actin, in the same orientation. It is hypothesised [...]


ensembl_gene_id: PAU_03705
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: PAU_03706
symbol: accB
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein of acetyl-coa carboxylase (bccp); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PAU_03707
symbol: accC
gene_biotype: protein_coding
description:
  Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: PAU_03711
symbol: panF
gene_biotype: protein_coding
description:
  Sodium/pantothenate symporter (pantothenate permease); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: PAU_03712
symbol: prmA
gene_biotype: protein_coding
description:
  Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: PAU_03713
symbol: dusB
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: PAU_03714
symbol: fis
gene_biotype: protein_coding
description:
  Dna-binding protein fis; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: PAU_03715
symbol: PAU_03715
gene_biotype: protein_coding
description:
  Similar to multidrug resistance protein; The MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients.


ensembl_gene_id: PAU_03717
symbol: PirB
gene_biotype: protein_coding
description:
  PirB similarities with putative juvenile hormone esterase; This family contains insecticidal toxins produced by Bacillus species of bacteria. During spore formation the bacteria produce crystals of this protein. When an insect ingests these proteins they are activated by proteolytic cleavage. The N-terminus is cleaved in all of the proteins and a C-terminal extension is cleaved in some members. Once activated the endotoxin binds to the gut epithelium and causes cell lysis by the formation of cation-selective channels, which leads to death. The activated toxin is composed of three disti [...]


ensembl_gene_id: PAU_03719
symbol: livF
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport atp-binding protein livf; Belongs to the ABC transporter superfamily.


ensembl_gene_id: PAU_03721
symbol: livM
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permeas protein livm; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PAU_03722
symbol: livH
gene_biotype: protein_coding
description:
  High-affinity branched-chain amino acid transport system permeas protein livh (liv-i protein h); Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: PAU_03724
symbol: panZ
gene_biotype: protein_coding
description:
  Hypothetical Protein; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family.


ensembl_gene_id: PAU_03726
symbol: rpoH
gene_biotype: protein_coding
description:
  Component of rna polymerase, sigma 32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: PAU_03727
symbol: ftsX
gene_biotype: protein_coding
description:
  Cell division protein ftsx; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: PAU_03728
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division atp-binding protein ftse; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: PAU_03729
symbol: ftsY
gene_biotype: protein_coding
description:
  Cell division protein ftsy; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: PAU_03730
symbol: PAU_03730
gene_biotype: protein_coding
description:
  Conserved hypothetical Protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: PAU_03736
symbol: tusA
gene_biotype: protein_coding
description:
  Sulfurtransferase; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.


ensembl_gene_id: PAU_03737
symbol: PAU_03737
gene_biotype: protein_coding
description:
  Conserved hypothetical Protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: PAU_03743
symbol: poxA
gene_biotype: protein_coding
description:
  Putative lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.


ensembl_gene_id: PAU_03749
symbol: frdB
gene_biotype: protein_coding
description:
  Fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: PAU_03750
symbol: frdC
gene_biotype: protein_coding
description:
  Fumarate reductase 15 kda hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: PAU_03751
symbol: frdD
gene_biotype: protein_coding
description:
  Fumarate reductase 13 kda hydrophobic protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: PAU_03752
symbol: sugE
gene_biotype: protein_coding
description:
  Quaternary ammonium compound-resistance protein suge; Members of this family which have been characterized, belong to the small multidrug resistance (Smr) protein family and are integral membrane proteins. They confer resistance to a wide range of toxic compounds by removing them for the cells. The efflux is coupled to an influx of protons.


ensembl_gene_id: PAU_03753
symbol: efp
gene_biotype: protein_coding
description:
  Elongation factor p (ef-p); Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: PAU_03756
symbol: groL
gene_biotype: protein_coding
description:
  60 kda chaperonin (protein cpn60) (groel protein); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: PAU_03757
symbol: groS
gene_biotype: protein_coding
description:
  10 kda chaperonin (protein cpn10) (groes protein); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: PAU_03762
symbol: dcuA
gene_biotype: protein_coding
description:
  Aspartate ammonia-lyase, pseudogene; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: PAU_03763
symbol: dsbD
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: PAU_03776
symbol: PAU_03776
gene_biotype: protein_coding
description:
  Short-chain dehydrogenase/reductase sdr; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: PAU_03780
symbol: PAU_03780
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Similar to toxic ion resistance protein; Belongs to the TelA family.


ensembl_gene_id: PAU_03787
symbol: PAU_03787
gene_biotype: protein_coding
description:
  Outer membrane protein, ompa/motb family; Most of the bacterial outer membrane proteins in this group are porin-like integral membrane proteins.


ensembl_gene_id: PAU_03845
symbol: PAU_03845
gene_biotype: protein_coding
description:
  This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in archaea, bacteria and eukaryotes. Analysis suggests that Rhomboid-1 is a novel intramembrane serine protease that directly cleaves the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor.


ensembl_gene_id: PAU_03853
symbol: queH
gene_biotype: protein_coding
description:
  Conserved hypothetical Protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).


ensembl_gene_id: PAU_03859
symbol: PAU_03859
gene_biotype: protein_coding
description:
  Putative usher protein (putative outer membrane usher protein); In Gram-negative bacteria the biogenesis of fimbriae (or pili.


ensembl_gene_id: PAU_03870
symbol: trkH
gene_biotype: protein_coding
description:
  Trk system potassium uptake protein trkh; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: PAU_03873
symbol: fadB
gene_biotype: protein_coding
description:
  Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: PAU_03874
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-coa thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: PAU_03876
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: PAU_03877
symbol: rfaH
gene_biotype: protein_coding
description:
  Transcriptional activator rfah; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.


ensembl_gene_id: PAU_03879
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: PAU_03880
symbol: tatB
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein tatb homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: PAU_03881
symbol: tatA
gene_biotype: protein_coding
description:
  Sec-independent protein translocase protein tata/e homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: PAU_03882
symbol: ubiB
gene_biotype: protein_coding
description:
  Probable ubiquinone biosynthesis protein ubib; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: PAU_03884
symbol: ubiE
gene_biotype: protein_coding
description:
  Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: PAU_03888
symbol: udp
gene_biotype: protein_coding
description:
  Uridine phosphorylase (udrpase); Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: PAU_03889
symbol: pcp
gene_biotype: protein_coding
description:
  Pyrrolidone-carboxylate peptidase 2; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.


ensembl_gene_id: PAU_03891
symbol: metE
gene_biotype: protein_coding
description:
  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: PAU_03893
symbol: PAU_03893
gene_biotype: protein_coding
description:
  Putative sodium/hydrogen exchanger family protein yjce; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: PAU_03902
symbol: PAU_03902
gene_biotype: protein_coding
description:
  Similar to colicin/pyocin immunity protein; This family includes bacterial colicin and pyocin immunity proteins. These immunity proteins can bind specifically to the DNase-type colicins and pyocins and inhibit their bactericidal activity.


ensembl_gene_id: PAU_03903
symbol: pys2
gene_biotype: protein_coding
description:
  Colicin structural protein; Bacteriocins are protein antibiotics that kill bacteria closely related to the producing species. Colicins are a subgroup of bacteriocins that are produced by and target Escherichia coli. The lethal action of most colicins is exerted either by formation of a pore in the cytoplasmic membrane of the target cell, or by an enzymatic nuclease digestion mechanism.


ensembl_gene_id: PAU_03904
symbol: usp-2
gene_biotype: protein_coding
description:
  Uropathogenic specific protein; Pyocins are polypeptide toxins produced by, and active against, bacteria. S-type pyocins cause cell death by DNA breakdown due to endonuclease activity.


ensembl_gene_id: PAU_03905
symbol: adhC
gene_biotype: protein_coding
description:
  Glutathione-dependent formaldehyde dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: PAU_03907
symbol: ssb
gene_biotype: protein_coding
description:
  Single-stranded dna-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: PAU_03908
symbol: uvrA
gene_biotype: protein_coding
description:
  Uvrabc system protein a (uvra protein) (excinuclease abc subunit a); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: PAU_03912
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase); Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: PAU_03913
symbol: dnaB
gene_biotype: protein_coding
description:
  Replicative dna helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: PAU_03915
symbol: dusA
gene_biotype: protein_coding
description:
  tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: PAU_03927
symbol: lexA
gene_biotype: protein_coding
description:
  LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: PAU_03928
symbol: dgkA
gene_biotype: protein_coding
description:
  Diacylglycerol kinase (dagk) (diglyceride kinase) (dgk); Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: PAU_03930
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: PAU_03931
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate--pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.


ensembl_gene_id: PAU_03943
symbol: fecC
gene_biotype: protein_coding
description:
  Iron(iii) dicitrate transport system permease protein fecc; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PAU_03944
symbol: fecD
gene_biotype: protein_coding
description:
  Iron(iii) dicitrate transport system permease protein fecd; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: PAU_03970
symbol: hsdR
gene_biotype: protein_coding
description:
  Type i site-specific deoxyribonuclease hsdr; Subunit R is required for both nuclease and ATPase activities, but not for modification.


ensembl_gene_id: PAU_03982
symbol: ampH
gene_biotype: protein_coding
description:
  Beta-lactamase (penicillin-binding protein amph); Beta-lactamase catalyses the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins.


ensembl_gene_id: PAU_03985
symbol: pepA
gene_biotype: protein_coding
description:
  Probable cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: PAU_03987
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: PAU_03996
symbol: yjgD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: PAU_03997
symbol: argI
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: PAU_03999
symbol: pyrB
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: PAU_04000
symbol: pyrI
gene_biotype: protein_coding
description:
  Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase.


ensembl_gene_id: PAU_04003
symbol: nrdG
gene_biotype: protein_coding
description:
  Nrdg subunit of ribonucleoside triphosphate reductase activase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: PAU_04014
symbol: PAU_04014
gene_biotype: protein_coding
description:
  CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: PAU_04023
symbol: deaD
gene_biotype: protein_coding
description:
  Cold-shock dead box protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: PAU_04025
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: PAU_04026
symbol: rpsO
gene_biotype: protein_coding
description:
  30s ribosomal subunit protein s15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: PAU_04027
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: PAU_04028
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor a; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: PAU_04029
symbol: infB
gene_biotype: protein_coding
description:
  Translation initiation factor if-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: PAU_04030
symbol: nusA
gene_biotype: protein_coding
description:
  N utilization substance protein a (nusa protein) (l factor); Participates in both transcription termination and antitermination.


ensembl_gene_id: PAU_04031
symbol: yhbC
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: PAU_04032
symbol: secG
gene_biotype: protein_coding
description:
  Protein-export membrane protein secg (preprotein translocase band subunit) (p12); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: PAU_04033
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: PAU_04034
symbol: folP
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: PAU_04035
symbol: mrsC
gene_biotype: protein_coding
description:
  ATP-binding protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: PAU_04036
symbol: rrmJ
gene_biotype: protein_coding
description:
  Ribosomal RNA large subunit methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: PAU_04038
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor grea (transcript cleavage facto grea); Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: PAU_04040
symbol: dacB
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4); Penicillin-binding protein.


ensembl_gene_id: PAU_04041
symbol: yhbZ
gene_biotype: protein_coding
description:
  Similar to hypothetical gtp-binding protein yhbz of escherichia coli; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: PAU_04043
symbol: rplU
gene_biotype: protein_coding
description:
  50s ribosomal protein l21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: PAU_04044
symbol: ispB
gene_biotype: protein_coding
description:
  Octaprenyl-diphosphate synthase (octaprenyl pyrophosphate synthetase (opp synthetase); Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: PAU_04050
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: PAU_04052
symbol: ppa
gene_biotype: protein_coding
description:
  Inorganic pyrophosphatase (pyrophosphate phospho-hydrolase) (ppase); Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: PAU_04056
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: PAU_04060
symbol: cysQ
gene_biotype: protein_coding
description:
  Protein cysq; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: PAU_04070
symbol: rpsR
gene_biotype: protein_coding
description:
  30s ribosomal subunit protein s18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: PAU_04071
symbol: priB
gene_biotype: protein_coding
description:
  Primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: PAU_04073
symbol: rlmB
gene_biotype: protein_coding
description:
  23S rRNA (guanosine-2'-o-)-methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.


ensembl_gene_id: PAU_04074
symbol: rnr
gene_biotype: protein_coding
description:
  Ribonuclease r (rnase r) (vacb protein); 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.


ensembl_gene_id: PAU_04075
symbol: yjeB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.


ensembl_gene_id: PAU_04076
symbol: purA2
gene_biotype: protein_coding
description:
  PurA, subunit of adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: PAU_04078
symbol: hflK
gene_biotype: protein_coding
description:
  Protease specific for phage lambda cii repressor; HflC and HflK could encode or regulate a protease.


ensembl_gene_id: PAU_04079
symbol: hflX
gene_biotype: protein_coding
description:
  Gtp-binding protein hflx; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: PAU_04080
symbol: hfq
gene_biotype: protein_coding
description:
  Hfq subunit of rna-binding homohexamer that affects many cellula processes; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: PAU_04081
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: PAU_04082
symbol: mutL
gene_biotype: protein_coding
description:
  Dna mismatch repair protein mutl; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: PAU_04085
symbol: yjeS
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: PAU_04088
symbol: orn
gene_biotype: protein_coding
description:
  Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: PAU_04089
symbol: yjeQ
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: PAU_04090
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: PAU_04116
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium transport protein cora; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: PAU_04119
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase xerc; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges t [...]


ensembl_gene_id: PAU_04121
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: PAU_04123
symbol: cyaY
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: PAU_04125
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: PAU_04126
symbol: hemD
gene_biotype: protein_coding
description:
  Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: PAU_04131
symbol: wecG
gene_biotype: protein_coding
description:
  Probable UDP-N-acetyl-D-mannosaminuronic acid transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.


ensembl_gene_id: PAU_04132
symbol: wzyE
gene_biotype: protein_coding
description:
  Putative eca polymerase; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.


ensembl_gene_id: PAU_04133
symbol: wecF
gene_biotype: protein_coding
description:
  4-alpha-L-fucosyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.


ensembl_gene_id: PAU_04134
symbol: wzxE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.


ensembl_gene_id: PAU_04135
symbol: wecE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein wece; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PAU_04136
symbol: wecD
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein rffc; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.


ensembl_gene_id: PAU_04137
symbol: rffH
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: PAU_04138
symbol: rffG
gene_biotype: protein_coding
description:
  Dtdp-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: PAU_04139
symbol: wecC
gene_biotype: protein_coding
description:
  Udp-n-acetyl-d-mannosaminuronic acid dehydrogenase (udp-mannac dehydrogenase); Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.


ensembl_gene_id: PAU_04140
symbol: wecB
gene_biotype: protein_coding
description:
  Udp-n-acetylglucosamine 2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.


ensembl_gene_id: PAU_04141
symbol: wzzE
gene_biotype: protein_coding
description:
  Lipopolysaccharide biosynthesis protein wzze; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.


ensembl_gene_id: PAU_04142
symbol: wecA
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-n-acetylglucosaminyltransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).


ensembl_gene_id: PAU_04143
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: PAU_04145
symbol: rhlB
gene_biotype: protein_coding
description:
  ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: PAU_04146
symbol: gppA
gene_biotype: protein_coding
description:
  Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.


ensembl_gene_id: PAU_04147
symbol: rep
gene_biotype: protein_coding
description:
  Rep helicase, a single-stranded DNA dependent ATPase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: PAU_04148
symbol: ilvC
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: PAU_04149
symbol: ilvY
gene_biotype: protein_coding
description:
  Transcriptional activator protein regulator Lys-R; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_04156
symbol: fabF-2
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: PAU_04159
symbol: PAU_04159
gene_biotype: protein_coding
description:
  Multidrug resistance secretion protein; emrA confers resistance to carbonylcyanide m-chlorophenylhydrazone, nalidixic acid, and a number of other toxic compounds.


ensembl_gene_id: PAU_04160
symbol: PAU_04160
gene_biotype: protein_coding
description:
  emrB confers resistance to carbonylcyanide m-chlorophenylhydrazone, nalidixic acid, and a number of other toxic compounds; Belongs to the major facilitator superfamily.


ensembl_gene_id: PAU_04161
symbol: ilvA
gene_biotype: protein_coding
description:
  Threonine dehydratase biosynthetic (threonine deaminase); Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: PAU_04163
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched-chain amino acid aminotransferase (transaminase b) (bcat); Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: PAU_04164
symbol: ilvM
gene_biotype: protein_coding
description:
  Acetolactate synthase isozyme ii small subunit (ahas-ii (acetohydroxy-acid synthase ii small subunit) (als-ii).


ensembl_gene_id: PAU_04173
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: PAU_04174
symbol: tsaC
gene_biotype: protein_coding
description:
  Conserved hypothetical Protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: PAU_04177
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: PAU_04178
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: PAU_04179
symbol: rsmB
gene_biotype: protein_coding
description:
  Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.


ensembl_gene_id: PAU_04191
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: PAU_04192
symbol: rpsD
gene_biotype: protein_coding
description:
  30s ribosomal subunit protein s4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: PAU_04193
symbol: rpsK
gene_biotype: protein_coding
description:
  30s ribosomal subunit protein s11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: PAU_04194
symbol: rpsM
gene_biotype: protein_coding
description:
  30s ribosomal subunit protein s13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: PAU_04196
symbol: secY
gene_biotype: protein_coding
description:
  Preprotein translocase secy subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: PAU_04197
symbol: rplO
gene_biotype: protein_coding
description:
  50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: PAU_04199
symbol: rpsE
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: PAU_04200
symbol: rplR
gene_biotype: protein_coding
description:
  50s ribosomal protein l18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: PAU_04201
symbol: rplF
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: PAU_04202
symbol: rpsH
gene_biotype: protein_coding
description:
  30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: PAU_04203
symbol: rpsN
gene_biotype: protein_coding
description:
  30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: PAU_04204
symbol: rplE
gene_biotype: protein_coding
description:
  50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: PAU_04205
symbol: rplX
gene_biotype: protein_coding
description:
  50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: PAU_04206
symbol: rplN
gene_biotype: protein_coding
description:
  50s ribosomal subunit protein l14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: PAU_04207
symbol: rpsQ
gene_biotype: protein_coding
description:
  Putative 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: PAU_04208
symbol: rplP
gene_biotype: protein_coding
description:
  50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: PAU_04209
symbol: rpsC
gene_biotype: protein_coding
description:
  30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: PAU_04210
symbol: rplV
gene_biotype: protein_coding
description:
  50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: PAU_04211
symbol: rpsS
gene_biotype: protein_coding
description:
  30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: PAU_04212
symbol: rplB
gene_biotype: protein_coding
description:
  50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: PAU_04213
symbol: rplW
gene_biotype: protein_coding
description:
  50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: PAU_04215
symbol: rplC
gene_biotype: protein_coding
description:
  50s ribosomal protein l3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: PAU_04216
symbol: rpsJ
gene_biotype: protein_coding
description:
  30s ribosomal subunit protein s10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: PAU_04218
symbol: bfr
gene_biotype: protein_coding
description:
  Bacterioferritin (bfr) (cytochrome b-1) (cytochrome b-557); Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: PAU_04221
symbol: tufA-2
gene_biotype: protein_coding
description:
  Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: PAU_04224
symbol: birA
gene_biotype: protein_coding
description:
  Bifunctional protein [includes: biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: PAU_04227
symbol: btuB
gene_biotype: protein_coding
description:
  Vitamin b12 transporter btub precursor (cobalamin receptor) (oute membrane cobalamin translocator); Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.


ensembl_gene_id: PAU_04228
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: PAU_04231
symbol: yijC
gene_biotype: protein_coding
description:
  Similar to tetr-family transcriptional regulatory protein yijc o escherichia coli; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.


ensembl_gene_id: PAU_04232
symbol: sthA
gene_biotype: protein_coding
description:
  Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: PAU_04233
symbol: oxyR
gene_biotype: protein_coding
description:
  Hydrogen peroxide-inducible genes activator (morphology and auto aggregation control protein); Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: PAU_04237
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: PAU_04239
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: PAU_04242
symbol: metF
gene_biotype: protein_coding
description:
  5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: PAU_04243
symbol: metL
gene_biotype: protein_coding
description:
  Aspartokinase ii and homoserine dehydrogenase ii (aspartokinase ii homoserine dehydrogenase ii); In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: PAU_04245
symbol: metJ
gene_biotype: protein_coding
description:
  Met repressor (met regulon regulatory protein metj); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.


ensembl_gene_id: PAU_04247
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein n'(= factor y)(putative helicase) (primosoma protein n'); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: PAU_04249
symbol: ftsN
gene_biotype: protein_coding
description:
  Cell division protein ftsn; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.


ensembl_gene_id: PAU_04250
symbol: hslV
gene_biotype: protein_coding
description:
  ATP-dependent protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: PAU_04251
symbol: hslU
gene_biotype: protein_coding
description:
  Atp-dependent hsl protease atp-binding subunit hslu; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: PAU_04252
symbol: menA
gene_biotype: protein_coding
description:
  1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: PAU_04253
symbol: rraA
gene_biotype: protein_coding
description:
  Regulator of ribonuclease activity a; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: PAU_04254
symbol: yiiU
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: PAU_04256
symbol: glpF
gene_biotype: protein_coding
description:
  Glycerol uptake facilitator protein (aquaglyceroporin); Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: PAU_04257
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: PAU_04258
symbol: emrD
gene_biotype: protein_coding
description:
  Mfs family, multidrug tranport protein; Multidrug resistance proteins are molecular pumps that participate in a low energy shock adaptive response in some bacteria. They mediate cellular resistance to toxicants.


ensembl_gene_id: PAU_04259
symbol: fpr
gene_biotype: protein_coding
description:
  Ferredoxin--nadp reductase (fnr) (flavodoxin reductase) flxr (fldr (methyl viologen resistance protein a) (da1).


ensembl_gene_id: PAU_04262
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: PAU_04264
symbol: pfkA
gene_biotype: protein_coding
description:
  6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: PAU_04269
symbol: vco27AB
gene_biotype: protein_coding
description:
  Relb protein; Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. Several toxin/antitoxin pairs may occur in a single species. RelE and RelB form a toxin-antitoxin system; RelE repr [...]


ensembl_gene_id: PAU_04300
symbol: PAU_04300
gene_biotype: protein_coding
description:
  Cytosine-specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.


ensembl_gene_id: PAU_04314
symbol: wblD
gene_biotype: protein_coding
description:
  Cys/met metabolism pyridoxal-phosphate-dependen enzymes:degt/dnrj/eryc1/strs aminotransferase:aromatic amino aci beta-eliminating lyase/threonine aldolase:aminotransferase, class and ii; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: PAU_04337
symbol: gna
gene_biotype: protein_coding
description:
  Udp-n-acetyl-d-galactosamine dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.


ensembl_gene_id: PAU_04343
symbol: galE
gene_biotype: protein_coding
description:
  Udp-glucose 4-epimerase (galactowaldenase) (udp-galactose 4 epimerase); Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: PAU_04344
symbol: yibK
gene_biotype: protein_coding
description:
  Hypothetical tRNA/rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: PAU_04346
symbol: gpsA
gene_biotype: protein_coding
description:
  Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: PAU_04347
symbol: secB
gene_biotype: protein_coding
description:
  Protein-export protein secb; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: PAU_04351
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: PAU_04352
symbol: kbl-2
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: PAU_04353
symbol: hldD
gene_biotype: protein_coding
description:
  ADP-L-glycero-d-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: PAU_04360
symbol: kdtA
gene_biotype: protein_coding
description:
  3-deoxy-d-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: PAU_04362
symbol: coaD
gene_biotype: protein_coding
description:
  Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: PAU_04363
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: PAU_04374
symbol: dfp
gene_biotype: protein_coding
description:
  Coenzyme A biosynthesis bifunctional protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: PAU_04375
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: PAU_04376
symbol: slmA
gene_biotype: protein_coding
description:
  Transcriptional repressor tetr-type; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: PAU_04377
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: PAU_04378
symbol: rph
gene_biotype: protein_coding
description:
  Ribonuclease ph; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: PAU_04381
symbol: PAU_04381
gene_biotype: protein_coding
description:
  Macrolide-efflux protein; MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients.


ensembl_gene_id: PAU_04385
symbol: selA
gene_biotype: protein_coding
description:
  L-seryl-tRNA(sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family.


ensembl_gene_id: PAU_04386
symbol: fdhE
gene_biotype: protein_coding
description:
  Formate dehydrogenase-n activity influencing protein fdhe; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.


ensembl_gene_id: PAU_04390
symbol: fdoI1
gene_biotype: protein_coding
description:
  Formate dehydrogenase, cytochrome b556(fdo) subunit (format dehydrogenase-o gamma subunit) (fdh-z gamma subunit) (aerobic format dehydrogenase cytochrome b556 subunit).


ensembl_gene_id: PAU_04391
symbol: fdoH1
gene_biotype: protein_coding
description:
  Formate dehydrogenase iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: PAU_04393
symbol: fdhD
gene_biotype: protein_coding
description:
  Protein fdhd homolog; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: PAU_04397
symbol: trmE
gene_biotype: protein_coding
description:
  Trna modification gtpase trme; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: PAU_04398
symbol: oxaA
gene_biotype: protein_coding
description:
  Similar to 60 kda inner-membrane protein yidc of escherichia coli; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: PAU_04399
symbol: yidD
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: PAU_04400
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


