# geneInfo

ensembl_gene_id: Shew_2501
symbol: Shew_2501
gene_biotype: protein_coding
description:
  TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter-related protein; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; KEGG: she:Shewmr4_2487 oligopeptide/dipeptide ABC transporter, ATPase subunit; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Shew_2502
symbol: Shew_2502
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2488 ABC transporter-related protein.


ensembl_gene_id: Shew_2503
symbol: fabV
gene_biotype: protein_coding
description:
  Short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.


ensembl_gene_id: Shew_2504
symbol: Shew_2504
gene_biotype: protein_coding
description:
  PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO1798 peptidyl-prolyl cis-trans isomerase D.


ensembl_gene_id: Shew_2506
symbol: lon
gene_biotype: protein_coding
description:
  Lon-A peptidase. Serine peptidase. MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: Shew_2507
symbol: clpX
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: Shew_2508
symbol: clpP
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: Shew_2509
symbol: tig
gene_biotype: protein_coding
description:
  Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: Shew_2510
symbol: folD
gene_biotype: protein_coding
description:
  Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: Shew_2511
symbol: cysS
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_2599 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Shew_2512
symbol: Shew_2512
gene_biotype: protein_coding
description:
  Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: Shew_2513
symbol: lpxH
gene_biotype: protein_coding
description:
  UDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Shew_2515
symbol: Shew_2515
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1282; KEGG: she:Shewmr4_2502 protein of unknown function DUF1282.


ensembl_gene_id: Shew_2516
symbol: glnS
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2571 glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase, class Ic.


ensembl_gene_id: Shew_2517
symbol: Shew_2517
gene_biotype: protein_coding
description:
  Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: Shew_2528
symbol: Shew_2528
gene_biotype: protein_coding
description:
  Transcriptional regulator, CdaR family; PFAM: sugar diacid recognition domain protein; KEGG: she:Shewmr4_2516 transcriptional regulator, CdaR.


ensembl_gene_id: Shew_2530
symbol: Shew_2530
gene_biotype: protein_coding
description:
  PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: vpa:VP2377 hypothetical protein.


ensembl_gene_id: Shew_2531
symbol: Shew_2531
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vpa:VP2378 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2532
symbol: Shew_2532
gene_biotype: protein_coding
description:
  Peptidase C26; PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: pen:PSEEN2659 glutamine amidopeptidase (class I).


ensembl_gene_id: Shew_2534
symbol: Shew_2534
gene_biotype: protein_coding
description:
  PFAM: glycerate kinase; KEGG: she:Shewmr4_2519 glycerate kinase; Belongs to the glycerate kinase type-1 family.


ensembl_gene_id: Shew_2537
symbol: Shew_2537
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO1762 transcriptional regulator, AraC/XylS family.


ensembl_gene_id: Shew_2539
symbol: Shew_2539
gene_biotype: protein_coding
description:
  PFAM: branched-chain amino acid transport; KEGG: she:Shewmr4_2529 branched-chain amino acid transport.


ensembl_gene_id: Shew_2540
symbol: Shew_2540
gene_biotype: protein_coding
description:
  PFAM: NIPSNAP family containing protein; KEGG: bur:Bcep18194_B0447 protein of unknown function DUF1099.


ensembl_gene_id: Shew_2541
symbol: Shew_2541
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: shm:Shewmr7_2605 helix-turn-helix, type 11 domain protein.


ensembl_gene_id: Shew_2542
symbol: Shew_2542
gene_biotype: protein_coding
description:
  PFAM: transcription activator, effector binding; KEGG: she:Shewmr4_2539 transcription activator, effector binding.


ensembl_gene_id: Shew_2544
symbol: Shew_2544
gene_biotype: protein_coding
description:
  PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: shm:Shewmr7_2608 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I.


ensembl_gene_id: Shew_2545
symbol: Shew_2545
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_3320 diguanylate cyclase.


ensembl_gene_id: Shew_2548
symbol: Shew_2548
gene_biotype: protein_coding
description:
  TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: vfi:VFA0260 glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Shew_2551
symbol: metAS
gene_biotype: protein_coding
description:
  Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: Shew_2553
symbol: Shew_2553
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_2667 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_2556
symbol: Shew_2556
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1694 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase.


ensembl_gene_id: Shew_2557
symbol: Shew_2557
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1693 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Shew_2558
symbol: menA
gene_biotype: protein_coding
description:
  1,4-Dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: Shew_2560
symbol: Shew_2560
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: she:Shewmr4_3851 transcriptional regulator, XRE family.


ensembl_gene_id: Shew_2561
symbol: Shew_2561
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: Shew_2562
symbol: Shew_2562
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, MarR; KEGG: ppr:PBPRB1157 putative transcriptional regulator, MarR family.


ensembl_gene_id: Shew_2563
symbol: Shew_2563
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: ppr:PBPRB1158 hypothetical alcohol dehydrogenase, zinc-containing.


ensembl_gene_id: Shew_2567
symbol: Shew_2567
gene_biotype: protein_coding
description:
  PFAM: MORN variant repeat protein; KEGG: fnu:FN2119 hypothetical exported 24-amino acid repeat protein.


ensembl_gene_id: Shew_2568
symbol: Shew_2568
gene_biotype: protein_coding
description:
  PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_2391 AMP-dependent synthetase and ligase.


ensembl_gene_id: Shew_2569
symbol: Shew_2569
gene_biotype: protein_coding
description:
  Transcriptional regulator, MerR family; PFAM: regulatory protein, MerR; KEGG: sdn:Sden_2244 regulatory protein, MerR.


ensembl_gene_id: Shew_2570
symbol: Shew_2570
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: shm:Shewmr7_2394 acyl-CoA dehydrogenase domain protein.


ensembl_gene_id: Shew_2571
symbol: Shew_2571
gene_biotype: protein_coding
description:
  Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: sdn:Sden_2246 propionyl-CoA carboxylase.


ensembl_gene_id: Shew_2573
symbol: Shew_2573
gene_biotype: protein_coding
description:
  3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: shm:Shewmr7_2397 carbamoyl-phosphate synthase L chain, ATP-binding protein.


ensembl_gene_id: Shew_2574
symbol: Shew_2574
gene_biotype: protein_coding
description:
  hydroxymethylglutaryl-CoA lyase; PFAM: pyruvate carboxyltransferase; KEGG: sfr:Sfri_2731 pyruvate carboxyltransferase.


ensembl_gene_id: Shew_2575
symbol: Shew_2575
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2399 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase.


ensembl_gene_id: Shew_2576
symbol: Shew_2576
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_2252 3-oxoacid CoA-transferase, subunit B; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase.


ensembl_gene_id: Shew_2577
symbol: Shew_2577
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1220 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.


ensembl_gene_id: Shew_2578
symbol: Shew_2578
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein, family 3; KEGG: ctc:CTC02323 sensory transduction protein kinase.


ensembl_gene_id: Shew_2581
symbol: Shew_2581
gene_biotype: protein_coding
description:
  Peptidyl-dipeptidase Dcp; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: she:Shewmr4_1355 peptidyl-dipeptidase DCP.


ensembl_gene_id: Shew_2583
symbol: Shew_2583
gene_biotype: protein_coding
description:
  PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: shm:Shewmr7_1418 electron transfer flavoprotein, alpha subunit.


ensembl_gene_id: Shew_2584
symbol: Shew_2584
gene_biotype: protein_coding
description:
  PFAM: electron transfer flavoprotein beta-subunit; KEGG: sfr:Sfri_2748 electron transfer flavoprotein beta-subunit.


ensembl_gene_id: Shew_2585
symbol: Shew_2585
gene_biotype: protein_coding
description:
  PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: shm:Shewmr7_1416 histone family protein nucleoid-structuring protein H-NS; Belongs to the histone-like protein H-NS family.


ensembl_gene_id: Shew_2589
symbol: Shew_2589
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0066; KEGG: she:Shewmr4_1347 protein of unknown function UPF0066.


ensembl_gene_id: Shew_2590
symbol: Shew_2590
gene_biotype: protein_coding
description:
  PFAM: transferase hexapeptide repeat containing protein; KEGG: sfr:Sfri_2752 transferase hexapeptide repeat-containing protein.


ensembl_gene_id: Shew_2593
symbol: Shew_2593
gene_biotype: protein_coding
description:
  PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_2285 AMP-dependent synthetase and ligase.


ensembl_gene_id: Shew_2596
symbol: proS
gene_biotype: protein_coding
description:
  prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]


ensembl_gene_id: Shew_2599
symbol: Shew_2599
gene_biotype: protein_coding
description:
  Transcriptional regulator, HxlR family; PFAM: helix-turn-helix, HxlR type; KEGG: vch:VCA0094 hypothetical protein.


ensembl_gene_id: Shew_2606
symbol: Shew_2606
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sfr:Sfri_1836 ABC transporter-related protein.


ensembl_gene_id: Shew_2607
symbol: Shew_2607
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1835 putative branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein.


ensembl_gene_id: Shew_2608
symbol: Shew_2608
gene_biotype: protein_coding
description:
  PFAM: inner-membrane translocator; KEGG: cps:CPS_3414 putative branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Shew_2609
symbol: Shew_2609
gene_biotype: protein_coding
description:
  PFAM: inner-membrane translocator; KEGG: cps:CPS_3415 putative branched-chain amino acid ABC transporter, permease protein; Belongs to the binding-protein-dependent transport system permease family.


ensembl_gene_id: Shew_2610
symbol: Shew_2610
gene_biotype: protein_coding
description:
  PFAM: AMP-dependent synthetase and ligase; KEGG: cps:CPS_3416 putative branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding.


ensembl_gene_id: Shew_2611
symbol: Shew_2611
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: cps:CPS_3417 putative branched-chain amino acid ABC transporter, ATP-binding protein.


ensembl_gene_id: Shew_2613
symbol: Shew_2613
gene_biotype: protein_coding
description:
  Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: sfr:Sfri_1829 periplasmic sensor hybrid histidine kinase.


ensembl_gene_id: Shew_2614
symbol: Shew_2614
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: cps:CPS_3420 DNA-binding response regulator, LuxR family.


ensembl_gene_id: Shew_2616
symbol: Shew_2616
gene_biotype: protein_coding
description:
  PFAM: lipolytic enzyme, G-D-S-L family; KEGG: bpm:BURPS1710b_0124 GDSL-like lipase/acylhydrolase domain protein.


ensembl_gene_id: Shew_2617
symbol: Shew_2617
gene_biotype: protein_coding
description:
  TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: shm:Shewmr7_2690 potassium efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Shew_2618
symbol: Shew_2618
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2691 diguanylate cyclase.


ensembl_gene_id: Shew_2619
symbol: tilS
gene_biotype: protein_coding
description:
  tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: Shew_2620
symbol: Shew_2620
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2693 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein.


ensembl_gene_id: Shew_2621
symbol: rnhB
gene_biotype: protein_coding
description:
  RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.


ensembl_gene_id: Shew_2622
symbol: lpxB
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Shew_2623
symbol: lpxA
gene_biotype: protein_coding
description:
  acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: Shew_2624
symbol: fabZ
gene_biotype: protein_coding
description:
  3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: Shew_2625
symbol: lpxD
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: Shew_2626
symbol: Shew_2626
gene_biotype: protein_coding
description:
  PFAM: outer membrane chaperone Skp (OmpH); KEGG: shm:Shewmr7_2699 outer membrane chaperone Skp (OmpH); Belongs to the skp family.


ensembl_gene_id: Shew_2627
symbol: bamA
gene_biotype: protein_coding
description:
  Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Shew_2628
symbol: Shew_2628
gene_biotype: protein_coding
description:
  KEGG: son:SO1636 membrane-associated zinc metalloprotease, putative; TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein.


ensembl_gene_id: Shew_2629
symbol: dxr
gene_biotype: protein_coding
description:
  1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.


ensembl_gene_id: Shew_2630
symbol: Shew_2630
gene_biotype: protein_coding
description:
  PFAM: phosphatidate cytidylyltransferase; KEGG: shm:Shewmr7_2703 phosphatidate cytidylyltransferase; Belongs to the CDS family.


ensembl_gene_id: Shew_2631
symbol: uppS
gene_biotype: protein_coding
description:
  Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: Shew_2632
symbol: frr
gene_biotype: protein_coding
description:
  Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: Shew_2634
symbol: tsf
gene_biotype: protein_coding
description:
  Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: Shew_2635
symbol: rpsB
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S2; KEGG: shm:Shewmr7_2708 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.


ensembl_gene_id: Shew_2636
symbol: map
gene_biotype: protein_coding
description:
  Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: Shew_2637
symbol: glnD
gene_biotype: protein_coding
description:
  UTP-GlnB uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.


ensembl_gene_id: Shew_2638
symbol: dapD
gene_biotype: protein_coding
description:
  TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; KEGG: sdn:Sden_1551 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family.


ensembl_gene_id: Shew_2640
symbol: purU
gene_biotype: protein_coding
description:
  Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: Shew_2641
symbol: Shew_2641
gene_biotype: protein_coding
description:
  TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: sfr:Sfri_1264 PTS system, glucose-like IIB subunint.


ensembl_gene_id: Shew_2653
symbol: syd
gene_biotype: protein_coding
description:
  Syd family protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: Shew_2654
symbol: queF
gene_biotype: protein_coding
description:
  GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: Shew_2656
symbol: Shew_2656
gene_biotype: protein_coding
description:
  PFAM: 4'-phosphopantetheinyl transferase; KEGG: son:SO1604 4'-phosphopantetheinyl transferase family protein; Belongs to the P-Pant transferase superfamily.


ensembl_gene_id: Shew_2658
symbol: Shew_2658
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: ppr:PBPRB1124 putative ABC transporter, ATP-binding protein.


ensembl_gene_id: Shew_2663
symbol: Shew_2663
gene_biotype: protein_coding
description:
  TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; elongation factor G, domain IV; KEGG: hch:HCH_03648 translation elongation factors (GTPase).


ensembl_gene_id: Shew_2665
symbol: Shew_2665
gene_biotype: protein_coding
description:
  PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR; KEGG: ppr:PBPRA1460 omega-3 polyunsaturated fatty acid synthase PfaA.


ensembl_gene_id: Shew_2667
symbol: Shew_2667
gene_biotype: protein_coding
description:
  PFAM: beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: ppr:PBPRA1458 omega-3 polyunsaturated fatty acid synthase PfaC; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Shew_2670
symbol: Shew_2670
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_0384 transcriptional regulator, LysR family protein.


ensembl_gene_id: Shew_2672
symbol: Shew_2672
gene_biotype: protein_coding
description:
  PFAM: Enoyl-CoA hydratase/isomerase; KEGG: stm:STM0070 carnitinyl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Shew_2674
symbol: Shew_2674
gene_biotype: protein_coding
description:
  PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: stt:t0073 L-carnitine dehydratase; Belongs to the CoA-transferase III family.


ensembl_gene_id: Shew_2675
symbol: Shew_2675
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sdy:SDY_0061 probable carnitine operon oxidoreductase.


ensembl_gene_id: Shew_2676
symbol: Shew_2676
gene_biotype: protein_coding
description:
  TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: spt:SPA0075 probable carnitine transporter; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: Shew_2677
symbol: Shew_2677
gene_biotype: protein_coding
description:
  PFAM: electron transfer flavoprotein beta-subunit; KEGG: sfv:SFV_0035 probable flavoprotein subunit of carnitine metabolism.


ensembl_gene_id: Shew_2678
symbol: Shew_2678
gene_biotype: protein_coding
description:
  PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: stm:STM0076 putative electron transfer flavoprotein, carnitine metabolism.


ensembl_gene_id: Shew_2679
symbol: Shew_2679
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; Part of an electron transfer system. Belongs to the ETF-QO/FixC family.


ensembl_gene_id: Shew_2681
symbol: Shew_2681
gene_biotype: protein_coding
description:
  PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: stm:STM0079 putative transport protein.


ensembl_gene_id: Shew_2687
symbol: Shew_2687
gene_biotype: protein_coding
description:
  TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0667 molybdenum ABC transporter, periplasmic molybdate-binding protein.


ensembl_gene_id: Shew_2688
symbol: Shew_2688
gene_biotype: protein_coding
description:
  Amidohydrolase; KEGG: sfr:Sfri_3605 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein.


ensembl_gene_id: Shew_2690
symbol: Shew_2690
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_1347 TonB-dependent receptor.


ensembl_gene_id: Shew_2695
symbol: Shew_2695
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: she:Shewmr4_3817 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_2696
symbol: Shew_2696
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: sdn:Sden_1263 ATP-binding region, ATPase-like protein.


ensembl_gene_id: Shew_2704
symbol: nqrF
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: Shew_2705
symbol: nqrE
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: Shew_2706
symbol: nqrD
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit D; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: Shew_2707
symbol: nqrC
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit C; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: Shew_2708
symbol: nqrB
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: Shew_2709
symbol: nqrA
gene_biotype: protein_coding
description:
  NADH:ubiquinone oxidoreductase, subunit A; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: Shew_2710
symbol: Shew_2710
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_0823 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.


ensembl_gene_id: Shew_2711
symbol: Shew_2711
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; Cupin 2, conserved barrel domain protein; KEGG: rru:Rru_A0140 transcriptional regulator, AraC family.


ensembl_gene_id: Shew_2713
symbol: Shew_2713
gene_biotype: protein_coding
description:
  PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: hch:HCH_00654 response regulator containing a CheY-like receiver domain and an HD-GYP domain.


ensembl_gene_id: Shew_2718
symbol: Shew_2718
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_0415 TonB-dependent receptor.


ensembl_gene_id: Shew_2723
symbol: Shew_2723
gene_biotype: protein_coding
description:
  PFAM: NUDIX hydrolase; KEGG: ppr:PBPRB0617 putative MutT/NUDIX family protein; Belongs to the Nudix hydrolase family.


ensembl_gene_id: Shew_2724
symbol: psuG
gene_biotype: protein_coding
description:
  Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.


ensembl_gene_id: Shew_2725
symbol: Shew_2725
gene_biotype: protein_coding
description:
  PFAM: PfkB domain protein; Helix-turn-helix, type 11 domain protein; KEGG: hch:HCH_01393 sugar kinase, ribokinase family.


ensembl_gene_id: Shew_2726
symbol: Shew_2726
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF188; KEGG: cps:CPS_3584 hypothetical protein; Belongs to the UPF0178 family.


ensembl_gene_id: Shew_2730
symbol: Shew_2730
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: son:SO1577 glutathione S-transferase family protein.


ensembl_gene_id: Shew_2733
symbol: Shew_2733
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; KEGG: chy:CHY_0724 ribosomal-protein-alanine acetyltransferase.


ensembl_gene_id: Shew_2734
symbol: Shew_2734
gene_biotype: protein_coding
description:
  TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; KEGG: shm:Shewmr7_0571 carboxymuconolactone decarboxylase.


ensembl_gene_id: Shew_2737
symbol: Shew_2737
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: cps:CPS_4694 transcriptional regulator, AraC family.


ensembl_gene_id: Shew_2738
symbol: Shew_2738
gene_biotype: protein_coding
description:
  Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: Shew_2739
symbol: Shew_2739
gene_biotype: protein_coding
description:
  PFAM: Fmu (Sun) domain protein; KEGG: son:SO1575 NOL1/NOP2/sun family putative RNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: Shew_2741
symbol: Shew_2741
gene_biotype: protein_coding
description:
  PFAM: glutathione peroxidase; KEGG: sdn:Sden_2552 glutathione peroxidase; Belongs to the glutathione peroxidase family.


ensembl_gene_id: Shew_2742
symbol: Shew_2742
gene_biotype: protein_coding
description:
  PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: she:Shewmr4_2706 peptidase M1, membrane alanine aminopeptidase.


ensembl_gene_id: Shew_2743
symbol: Shew_2743
gene_biotype: protein_coding
description:
  PFAM: Peptidase M9A, collagenase C-terminal domain protein; KEGG: cps:CPS_1458 microbial collagenase.


ensembl_gene_id: Shew_2748
symbol: Shew_2748
gene_biotype: protein_coding
description:
  PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: son:SO1559 phosphate regulon sensor protein PhoR.


ensembl_gene_id: Shew_2749
symbol: Shew_2749
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO1558 phosphate regulon response regulator PhoB.


ensembl_gene_id: Shew_2752
symbol: Shew_2752
gene_biotype: protein_coding
description:
  PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_2712 peptidase M61 domain protein.


ensembl_gene_id: Shew_2753
symbol: Shew_2753
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_2713 TPR repeat-containing protein.


ensembl_gene_id: Shew_2754
symbol: Shew_2754
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2782 diguanylate cyclase.


ensembl_gene_id: Shew_2755
symbol: Shew_2755
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein 730; KEGG: shm:Shewmr7_2783 conserved hypothetical protein 730.


ensembl_gene_id: Shew_2756
symbol: xni
gene_biotype: protein_coding
description:
  5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: Shew_2759
symbol: Shew_2759
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: shm:Shewmr7_2790 peptidase S9, prolyl oligopeptidase active site domain protein.


ensembl_gene_id: Shew_2760
symbol: Shew_2760
gene_biotype: protein_coding
description:
  PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: sdn:Sden_2561 isocitrate dehydrogenase (NAD+).


ensembl_gene_id: Shew_2761
symbol: rlmM
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: Shew_2764
symbol: Shew_2764
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1533 glycine cleavage system transcriptional activator, putative.


ensembl_gene_id: Shew_2766
symbol: thiI
gene_biotype: protein_coding
description:
  Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: Shew_2769
symbol: xseB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: Shew_2770
symbol: Shew_2770
gene_biotype: protein_coding
description:
  Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: son:SO1526 geranyltranstransferase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: Shew_2771
symbol: dxs
gene_biotype: protein_coding
description:
  1-Deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: Shew_2772
symbol: grpE
gene_biotype: protein_coding
description:
  GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]


ensembl_gene_id: Shew_2773
symbol: nadK
gene_biotype: protein_coding
description:
  NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: Shew_2775
symbol: Shew_2775
gene_biotype: protein_coding
description:
  TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO1506 MATE efflux family protein.


ensembl_gene_id: Shew_2777
symbol: Shew_2777
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_2752 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family.


ensembl_gene_id: Shew_2778
symbol: Shew_2778
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_2753 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type, transmembrane region; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_2781
symbol: Shew_2781
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_1066 diguanylate cyclase/phosphodiesterase.


ensembl_gene_id: Shew_2785
symbol: Shew_2785
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_1135 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_2790
symbol: Shew_2790
gene_biotype: protein_coding
description:
  PFAM: nucleoside recognition domain protein; KEGG: she:Shewmr4_1058 nucleoside recognition domain protein.


ensembl_gene_id: Shew_2791
symbol: Shew_2791
gene_biotype: protein_coding
description:
  PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; KEGG: son:SO0341 sensory box protein.


ensembl_gene_id: Shew_2795
symbol: Shew_2795
gene_biotype: protein_coding
description:
  PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfr:Sfri_3048 xanthine/uracil/vitamin C permease.


ensembl_gene_id: Shew_2797
symbol: Shew_2797
gene_biotype: protein_coding
description:
  TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: sfr:Sfri_1995 trimethylamine-N-oxide reductase C-type cytochrome TorC; Belongs to the TorC/TorY family.


ensembl_gene_id: Shew_2798
symbol: Shew_2798
gene_biotype: protein_coding
description:
  TIGRFAM: trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfr:Sfri_1994 trimethylamine-N-oxide reductase TorA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Shew_2799
symbol: torD
gene_biotype: protein_coding
description:
  Cytoplasmic chaperone TorD family protein; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily.


ensembl_gene_id: Shew_2800
symbol: Shew_2800
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_1161 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family.


ensembl_gene_id: Shew_2801
symbol: Shew_2801
gene_biotype: protein_coding
description:
  Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: sfr:Sfri_1992 multi-sensor hybrid histidine kinase.


ensembl_gene_id: Shew_2802
symbol: Shew_2802
gene_biotype: protein_coding
description:
  TIGRFAM: TonB box domain protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sfr:Sfri_1991 periplasmic binding protein/LacI transcriptional regulator.


ensembl_gene_id: Shew_2803
symbol: Shew_2803
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfr:Sfri_1990 two component transcriptional regulator, winged helix family protein.


ensembl_gene_id: Shew_2804
symbol: Shew_2804
gene_biotype: protein_coding
description:
  Type IV pilus assembly PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.


ensembl_gene_id: Shew_2810
symbol: Shew_2810
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1042 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase.


ensembl_gene_id: Shew_2812
symbol: deoD
gene_biotype: protein_coding
description:
  TIGRFAM: purine nucleoside phosphorylase; PFAM: purine and other phosphorylases, family 1; KEGG: shm:Shewmr7_1105 purine nucleoside phosphorylase.


ensembl_gene_id: Shew_2813
symbol: deoB
gene_biotype: protein_coding
description:
  Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: Shew_2814
symbol: deoA
gene_biotype: protein_coding
description:
  Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: Shew_2815
symbol: deoC
gene_biotype: protein_coding
description:
  Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: Shew_2816
symbol: Shew_2816
gene_biotype: protein_coding
description:
  PFAM: nucleoside-specific channel-forming protein, Tsx; KEGG: shm:Shewmr7_1101 nucleoside-specific channel-forming protein, Tsx.


ensembl_gene_id: Shew_2817
symbol: Shew_2817
gene_biotype: protein_coding
description:
  TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: shm:Shewmr7_1100 nucleoside transporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.


ensembl_gene_id: Shew_2820
symbol: prfC
gene_biotype: protein_coding
description:
  Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: Shew_2822
symbol: pnp
gene_biotype: protein_coding
description:
  Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: Shew_2823
symbol: Shew_2823
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_1095 diguanylate cyclase/phosphodiesterase.


ensembl_gene_id: Shew_2824
symbol: rpsO
gene_biotype: protein_coding
description:
  SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.


ensembl_gene_id: Shew_2825
symbol: truB
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: Shew_2826
symbol: rbfA
gene_biotype: protein_coding
description:
  Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: Shew_2827
symbol: infB
gene_biotype: protein_coding
description:
  Bacterial translation initiation factor 2 (bIF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: Shew_2829
symbol: rimP
gene_biotype: protein_coding
description:
  Protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.


ensembl_gene_id: Shew_2830
symbol: Shew_2830
gene_biotype: protein_coding
description:
  Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: Shew_2831
symbol: tpiA
gene_biotype: protein_coding
description:
  Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: Shew_2832
symbol: glmM
gene_biotype: protein_coding
description:
  Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: Shew_2833
symbol: Shew_2833
gene_biotype: protein_coding
description:
  Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: Shew_2834
symbol: ftsH
gene_biotype: protein_coding
description:
  Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: Shew_2835
symbol: rlmE
gene_biotype: protein_coding
description:
  Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: Shew_2836
symbol: Shew_2836
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0044; KEGG: shm:Shewmr7_1082 protein of unknown function UPF0044.


ensembl_gene_id: Shew_2837
symbol: greA
gene_biotype: protein_coding
description:
  Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: Shew_2838
symbol: carB
gene_biotype: protein_coding
description:
  TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: son:SO1142 carbamoyl-phosphate synthase large chain; Belongs to the CarB family.


ensembl_gene_id: Shew_2839
symbol: carA
gene_biotype: protein_coding
description:
  TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; KEGG: she:Shewmr4_0965 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.


ensembl_gene_id: Shew_2840
symbol: dapB
gene_biotype: protein_coding
description:
  Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.


ensembl_gene_id: Shew_2841
symbol: Shew_2841
gene_biotype: protein_coding
description:
  Peptidylprolyl isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: shm:Shewmr7_1001 peptidylprolyl isomerase, FKBP-type.


ensembl_gene_id: Shew_2843
symbol: dnaJ
gene_biotype: protein_coding
description:
  Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]


ensembl_gene_id: Shew_2845
symbol: Shew_2845
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6, transmembrane; KEGG: she:Shewmr4_0956 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Shew_2847
symbol: proA
gene_biotype: protein_coding
description:
  Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: Shew_2848
symbol: proB
gene_biotype: protein_coding
description:
  Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: Shew_2849
symbol: Shew_2849
gene_biotype: protein_coding
description:
  PFAM: Xanthine/uracil/vitamin C permease; KEGG: shm:Shewmr7_0989 xanthine/uracil/vitamin C permease.


ensembl_gene_id: Shew_2851
symbol: Shew_2851
gene_biotype: protein_coding
description:
  PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: she:Shewmr4_0949 peptidase M17, leucyl aminopeptidase domain protein; Belongs to the peptidase M17 family.


ensembl_gene_id: Shew_2852
symbol: Shew_2852
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_0986 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein.


ensembl_gene_id: Shew_2857
symbol: Shew_2857
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bcn:Bcen_5015 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2858
symbol: Shew_2858
gene_biotype: protein_coding
description:
  KEGG: bur:Bcep18194_B3098 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Shew_2860
symbol: Shew_2860
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sfr:Sfri_2069 acyl-CoA dehydrogenase domain protein.


ensembl_gene_id: Shew_2862
symbol: Shew_2862
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: reu:Reut_C6406 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_2863
symbol: Shew_2863
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bur:Bcep18194_B3036 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_2864
symbol: Shew_2864
gene_biotype: protein_coding
description:
  PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pat:Patl_1916 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Shew_2867
symbol: Shew_2867
gene_biotype: protein_coding
description:
  Pyruvate carboxylase, propionyl-CoA carboxylase; PFAM: carboxyl transferase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: pae:PA1400 pyruvate carboxylase subunit A.


ensembl_gene_id: Shew_2869
symbol: Shew_2869
gene_biotype: protein_coding
description:
  PFAM: peptidase S15; X-Pro dipeptidyl-peptidase C-terminal domain protein; KEGG: cps:CPS_3343 putative acylase.


ensembl_gene_id: Shew_2870
symbol: Shew_2870
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_3344 TonB-dependent receptor.


ensembl_gene_id: Shew_2871
symbol: dinB
gene_biotype: protein_coding
description:
  DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: Shew_2872
symbol: Shew_2872
gene_biotype: protein_coding
description:
  Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: Shew_2874
symbol: Shew_2874
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF539; KEGG: shm:Shewmr7_0981 protein of unknown function DUF539.


ensembl_gene_id: Shew_2882
symbol: luxS
gene_biotype: protein_coding
description:
  Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: Shew_2883
symbol: Shew_2883
gene_biotype: protein_coding
description:
  Transcriptional regulator BolA; PFAM: BolA family protein; KEGG: she:Shewmr4_0932 BolA family protein; Belongs to the BolA/IbaG family.


ensembl_gene_id: Shew_2886
symbol: rlmG
gene_biotype: protein_coding
description:
  rRNA (guanine-N(2)-)-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.


ensembl_gene_id: Shew_2892
symbol: Shew_2892
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_0812 major facilitator superfamily MFS_1.


ensembl_gene_id: Shew_2893
symbol: Shew_2893
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF520; KEGG: sdn:Sden_0770 protein of unknown function DUF520; Belongs to the UPF0234 family.


ensembl_gene_id: Shew_2895
symbol: Shew_2895
gene_biotype: protein_coding
description:
  2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.


ensembl_gene_id: Shew_2896
symbol: Shew_2896
gene_biotype: protein_coding
description:
  PFAM: sodium:neurotransmitter symporter; KEGG: ppr:PBPRA1510 putative sodium-dependent transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.


ensembl_gene_id: Shew_2897
symbol: Shew_2897
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vpa:VPA0041 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2899
symbol: gshB
gene_biotype: protein_coding
description:
  PFAM: glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; KEGG: vvy:VVA0031 putative glutathione synthase; Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: Shew_2901
symbol: Shew_2901
gene_biotype: protein_coding
description:
  PFAM: phosphoesterase, PA-phosphatase related; KEGG: gbe:GbCGDNIH1_2224 phosphoesterase, PAP2 family.


ensembl_gene_id: Shew_2902
symbol: Shew_2902
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: sdn:Sden_3066 chemotaxis sensory transducer.


ensembl_gene_id: Shew_2904
symbol: kdsA
gene_biotype: protein_coding
description:
  TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: she:Shewmr4_3163 2-dehydro-3-deoxyphosphooctonate aldolase.


ensembl_gene_id: Shew_2905
symbol: Shew_2905
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF819; KEGG: shm:Shewmr7_0802 protein of unknown function DUF819.


ensembl_gene_id: Shew_2907
symbol: Shew_2907
gene_biotype: protein_coding
description:
  PFAM: Invasion gene expression up-regulator, SirB; KEGG: shm:Shewmr7_0800 invasion gene expression up-regulator, SirB.


ensembl_gene_id: Shew_2908
symbol: Shew_2908
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bur:Bcep18194_A5736 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2911
symbol: prmC
gene_biotype: protein_coding
description:
  Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: Shew_2912
symbol: prfA
gene_biotype: protein_coding
description:
  Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: Shew_2913
symbol: hemA
gene_biotype: protein_coding
description:
  glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: Shew_2914
symbol: lolB
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: Shew_2915
symbol: ispE
gene_biotype: protein_coding
description:
  4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.


ensembl_gene_id: Shew_2916
symbol: prs
gene_biotype: protein_coding
description:
  Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: Shew_2919
symbol: ychF
gene_biotype: protein_coding
description:
  GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: Shew_2920
symbol: pth
gene_biotype: protein_coding
description:
  peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: Shew_2921
symbol: Shew_2921
gene_biotype: protein_coding
description:
  TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: shm:Shewmr7_1071 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family.


ensembl_gene_id: Shew_2923
symbol: miaB
gene_biotype: protein_coding
description:
  tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: Shew_2925
symbol: ybeY
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: Shew_2926
symbol: Shew_2926
gene_biotype: protein_coding
description:
  PFAM: CBS domain containing protein; transporter-associated region; KEGG: shm:Shewmr7_1066 CBS domain containing protein.


ensembl_gene_id: Shew_2927
symbol: lnt
gene_biotype: protein_coding
description:
  Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: Shew_2928
symbol: Shew_2928
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1451; KEGG: shm:Shewmr7_1063 protein of unknown function DUF1451.


ensembl_gene_id: Shew_2929
symbol: leuS
gene_biotype: protein_coding
description:
  TIGRFAM: leucyl-tRNA synthetase; KEGG: sdn:Sden_0797 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Shew_2930
symbol: lptE
gene_biotype: protein_coding
description:
  Rare lipoprotein B; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: Shew_2931
symbol: Shew_2931
gene_biotype: protein_coding
description:
  KEGG: son:SO1172 DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta.


ensembl_gene_id: Shew_2932
symbol: nadD
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: Shew_2933
symbol: rsfS
gene_biotype: protein_coding
description:
  Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: Shew_2934
symbol: rlmH
gene_biotype: protein_coding
description:
  Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: Shew_2936
symbol: mrdB
gene_biotype: protein_coding
description:
  Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: Shew_2938
symbol: rlpA
gene_biotype: protein_coding
description:
  Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: Shew_2939
symbol: Shew_2939
gene_biotype: protein_coding
description:
  Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: she:Shewmr4_0987 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.


ensembl_gene_id: Shew_2940
symbol: Shew_2940
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF493; KEGG: shm:Shewmr7_1051 protein of unknown function DUF493; Belongs to the UPF0250 family.


ensembl_gene_id: Shew_2941
symbol: lipB
gene_biotype: protein_coding
description:
  Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: Shew_2942
symbol: lipA
gene_biotype: protein_coding
description:
  Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: Shew_2943
symbol: Shew_2943
gene_biotype: protein_coding
description:
  SSU ribosomal protein S18P alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.


ensembl_gene_id: Shew_2945
symbol: Shew_2945
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3070 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Shew_2948
symbol: clpB
gene_biotype: protein_coding
description:
  ATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: Shew_2949
symbol: Shew_2949
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF152; KEGG: son:SO3578 conserved hypothetical protein TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family.


ensembl_gene_id: Shew_2950
symbol: Shew_2950
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Shew_2951
symbol: bamD
gene_biotype: protein_coding
description:
  Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Shew_2952
symbol: Shew_2952
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3076 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_2953
symbol: Shew_2953
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; CHASE4 domain protein; KEGG: sfr:Sfri_3981 diguanylate cyclase.


ensembl_gene_id: Shew_2954
symbol: Shew_2954
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_3174 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_2956
symbol: Shew_2956
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_0791 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Shew_2959
symbol: Shew_2959
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4542 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2960
symbol: Shew_2960
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: son:SO4539 serine protease, subtilase family; Belongs to the peptidase S8 family.


ensembl_gene_id: Shew_2962
symbol: maeA
gene_biotype: protein_coding
description:
  PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: shm:Shewmr7_0778 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Belongs to the malic enzymes family.


ensembl_gene_id: Shew_2967
symbol: Shew_2967
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3184 TonB-dependent receptor.


ensembl_gene_id: Shew_2968
symbol: Shew_2968
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: she:Shewmr4_3183 glutathione S-transferase, N-terminal domain protein; Belongs to the GST superfamily.


ensembl_gene_id: Shew_2973
symbol: Shew_2973
gene_biotype: protein_coding
description:
  Endothelin-converting enzyme 1; PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_3179 endothelin-converting enzyme 1.


ensembl_gene_id: Shew_2974
symbol: Shew_2974
gene_biotype: protein_coding
description:
  PFAM: transferase hexapeptide repeat containing protein; KEGG: vpa:VPA1135 putative acetyltransferase.


ensembl_gene_id: Shew_2975
symbol: Shew_2975
gene_biotype: protein_coding
description:
  PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_0788 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Shew_2977
symbol: Shew_2977
gene_biotype: protein_coding
description:
  Diguanylate cyclase; KEGG: son:SO3859 cyclic nucleotide phosphodiesterase, putative; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein.


ensembl_gene_id: Shew_2979
symbol: queG
gene_biotype: protein_coding
description:
  Putative iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: Shew_2984
symbol: Shew_2984
gene_biotype: protein_coding
description:
  PFAM: ferredoxin-dependent glutamate synthase; SMART: zinc finger, CDGSH-type domain protein; KEGG: cps:CPS_1903 glutamate synthase domain protein; Belongs to the glutamate synthase family.


ensembl_gene_id: Shew_2986
symbol: metE
gene_biotype: protein_coding
description:
  Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: Shew_2987
symbol: Shew_2987
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0653 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2990
symbol: Shew_2990
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO0815 TonB-dependent receptor C-terminal domain protein.


ensembl_gene_id: Shew_2994
symbol: Shew_2994
gene_biotype: protein_coding
description:
  Transcriptional repressor, CopY family; PFAM: Penicillinase repressor; KEGG: sfr:Sfri_3585 transcriptional repressor, CopY family protein.


ensembl_gene_id: Shew_2998
symbol: Shew_2998
gene_biotype: protein_coding
description:
  PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sdn:Sden_0949 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase.


ensembl_gene_id: Shew_3000
symbol: Shew_3000
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cps:CPS_0546 GGDEF domain protein.


ensembl_gene_id: Shew_3001
symbol: Shew_3001
gene_biotype: protein_coding
description:
  SMART: extracellular solute-binding protein, family 3; KEGG: cps:CPS_4167 sodium:dicarboxylate symporter family/bacterial extracellular solute-binding family 3 protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Shew_3003
symbol: Shew_3003
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAb0374 acyl-coenzyme A dehydrogenase (ACDH).


ensembl_gene_id: Shew_3004
symbol: Shew_3004
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: shm:Shewmr7_2809 protein of unknown function DUF224, cysteine-rich region domain protein.


ensembl_gene_id: Shew_3005
symbol: Shew_3005
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_2810 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_3007
symbol: Shew_3007
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_1855 transcriptional regulator, LysR family protein.


ensembl_gene_id: Shew_3017
symbol: Shew_3017
gene_biotype: protein_coding
description:
  PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: she:Shewmr4_3310 glycerophosphoryl diester phosphodiesterase.


ensembl_gene_id: Shew_3020
symbol: Shew_3020
gene_biotype: protein_coding
description:
  Hypothetical protein; Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety; Belongs to the PagL family.


ensembl_gene_id: Shew_3023
symbol: Shew_3023
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sfr:Sfri_0758 diguanylate cyclase.


ensembl_gene_id: Shew_3028
symbol: Shew_3028
gene_biotype: protein_coding
description:
  PFAM: phospholipase D/Transphosphatidylase; KEGG: sdn:Sden_1075 phospholipase D/transphosphatidylase.


ensembl_gene_id: Shew_3029
symbol: Shew_3029
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF985; KEGG: she:Shewmr4_3317 protein of unknown function DUF985.


ensembl_gene_id: Shew_3033
symbol: Shew_3033
gene_biotype: protein_coding
description:
  TIGRFAM: uncharacterized domain; PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: she:Shewmr4_3321 uncharacterized domain.


ensembl_gene_id: Shew_3034
symbol: Shew_3034
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tcx:Tcr_0397 diguanylate cyclase (GGDEF domain).


ensembl_gene_id: Shew_3037
symbol: Shew_3037
gene_biotype: protein_coding
description:
  TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: RimK domain protein ATP-grasp; KEGG: sdn:Sden_3770 S6 modification enzyme RimK; Belongs to the RimK family.


ensembl_gene_id: Shew_3038
symbol: Shew_3038
gene_biotype: protein_coding
description:
  TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: sdn:Sden_3771 asparagine synthase, glutamine-hydrolyzing.


ensembl_gene_id: Shew_3039
symbol: Shew_3039
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF159; KEGG: sdn:Sden_3234 protein of unknown function DUF159; Belongs to the SOS response-associated peptidase family.


ensembl_gene_id: Shew_3044
symbol: Shew_3044
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ppr:PBPRB0028 hypothetical methyl-accepting chemotaxisprotein.


ensembl_gene_id: Shew_3048
symbol: Shew_3048
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pfl:PFL_2420 D-isomer specific 2-hydroxyacid dehydrogenase family protein.


ensembl_gene_id: Shew_3051
symbol: Shew_3051
gene_biotype: protein_coding
description:
  PFAM: Cupin 2, conserved barrel domain protein; KEGG: rfr:Rfer_2441 carboxymuconolactone decarboxylase.


ensembl_gene_id: Shew_3052
symbol: Shew_3052
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: rso:RSc0625 probable transcription regulator protein.


ensembl_gene_id: Shew_3062
symbol: gcvP
gene_biotype: protein_coding
description:
  Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: Shew_3063
symbol: gcvH
gene_biotype: protein_coding
description:
  Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: Shew_3064
symbol: gcvT
gene_biotype: protein_coding
description:
  Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.


ensembl_gene_id: Shew_3065
symbol: Shew_3065
gene_biotype: protein_coding
description:
  TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0778 oxidoreductase, FAD-binding, UbiH/Coq6 family.


ensembl_gene_id: Shew_3066
symbol: Shew_3066
gene_biotype: protein_coding
description:
  TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: she:Shewmr4_3333 2-polyprenyl-6-methoxyphenol 4-hydroxylase.


ensembl_gene_id: Shew_3067
symbol: Shew_3067
gene_biotype: protein_coding
description:
  TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: shm:Shewmr7_0619 YecA family protein; Belongs to the UPF0149 family.


ensembl_gene_id: Shew_3068
symbol: Shew_3068
gene_biotype: protein_coding
description:
  Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: Shew_3069
symbol: Shew_3069
gene_biotype: protein_coding
description:
  PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: shm:Shewmr7_0617 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.


ensembl_gene_id: Shew_3073
symbol: ung
gene_biotype: protein_coding
description:
  Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: Shew_3076
symbol: Shew_3076
gene_biotype: protein_coding
description:
  PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_3132 lysine exporter protein (LysE/YggA).


ensembl_gene_id: Shew_3077
symbol: Shew_3077
gene_biotype: protein_coding
description:
  PFAM: peptidase S10, serine carboxypeptidase; KEGG: she:Shewmr4_0889 peptidase S10, serine carboxypeptidase.


ensembl_gene_id: Shew_3078
symbol: Shew_3078
gene_biotype: protein_coding
description:
  PFAM: Ppx/GppA phosphatase; KEGG: she:Shewmr4_2208 Ppx/GppA phosphatase; Belongs to the GppA/Ppx family.


ensembl_gene_id: Shew_3079
symbol: ppk
gene_biotype: protein_coding
description:
  Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: Shew_3081
symbol: Shew_3081
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_3096 TonB-dependent receptor.


ensembl_gene_id: Shew_3082
symbol: Shew_3082
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0887 transcriptional regulator, fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase.


ensembl_gene_id: Shew_3083
symbol: Shew_3083
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3136 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_3084
symbol: Shew_3084
gene_biotype: protein_coding
description:
  PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_3139 AMP-dependent synthetase and ligase.


ensembl_gene_id: Shew_3085
symbol: Shew_3085
gene_biotype: protein_coding
description:
  Lipocalin family protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: Shew_3087
symbol: Shew_3087
gene_biotype: protein_coding
description:
  KEGG: son:SO3665 ABC transporter, ATP-binding/permease protein, putative; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter-related protein; SMART: AAA ATPase.


ensembl_gene_id: Shew_3088
symbol: Shew_3088
gene_biotype: protein_coding
description:
  PFAM: short chain fatty acid transporter; KEGG: shm:Shewmr7_2886 short chain fatty acid transporter.


ensembl_gene_id: Shew_3093
symbol: Shew_3093
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF924; KEGG: she:Shewmr4_0877 protein of unknown function DUF924.


ensembl_gene_id: Shew_3097
symbol: Shew_3097
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_3717 TonB-dependent siderophore receptor.


ensembl_gene_id: Shew_3098
symbol: Shew_3098
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: ppr:PBPRB1366 putative NADH-dependent flavin oxidoreductase.


ensembl_gene_id: Shew_3103
symbol: Shew_3103
gene_biotype: protein_coding
description:
  PFAM: aldehyde dehydrogenase; KEGG: son:SO3683 coniferyl aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Shew_3105
symbol: Shew_3105
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pat:Patl_2651 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3107
symbol: Shew_3107
gene_biotype: protein_coding
description:
  PFAM: peptidase M19, renal dipeptidase; KEGG: shm:Shewmr7_0834 twin-arginine translocation pathway signal.


ensembl_gene_id: Shew_3109
symbol: Shew_3109
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_1975 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Shew_3111
symbol: Shew_3111
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ppr:PBPRB1065 hypothetical oxidoreductase protein.


ensembl_gene_id: Shew_3112
symbol: Shew_3112
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3690 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Shew_3113
symbol: Shew_3113
gene_biotype: protein_coding
description:
  Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: extracellular solute-binding protein, family 3; KEGG: sfr:Sfri_3689 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_3114
symbol: Shew_3114
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_3688 two component, sigma54 specific, transcriptional regulator, fis family protein.


ensembl_gene_id: Shew_3115
symbol: Shew_3115
gene_biotype: protein_coding
description:
  PFAM: sodium:dicarboxylate symporter; KEGG: sdn:Sden_2987 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Shew_3123
symbol: Shew_3123
gene_biotype: protein_coding
description:
  Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: Shew_3124
symbol: Shew_3124
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3407 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like.


ensembl_gene_id: Shew_3125
symbol: Shew_3125
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_3409 diguanylate cyclase/phosphodiesterase.


ensembl_gene_id: Shew_3126
symbol: Shew_3126
gene_biotype: protein_coding
description:
  2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: Shew_3128
symbol: sfsA
gene_biotype: protein_coding
description:
  PFAM: sugar fermentation stimulation protein; KEGG: sdn:Sden_3169 sugar fermentation stimulation protein; Belongs to the SfsA family.


ensembl_gene_id: Shew_3129
symbol: dksA
gene_biotype: protein_coding
description:
  Transcriptional regulator, TraR/DksA family; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: Shew_3130
symbol: gluQ
gene_biotype: protein_coding
description:
  Glutamate--tRNA ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: Shew_3131
symbol: pcnB
gene_biotype: protein_coding
description:
  poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: Shew_3132
symbol: Shew_3132
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3295 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.


ensembl_gene_id: Shew_3133
symbol: panB
gene_biotype: protein_coding
description:
  3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: Shew_3134
symbol: panC
gene_biotype: protein_coding
description:
  Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: Shew_3135
symbol: Shew_3135
gene_biotype: protein_coding
description:
  L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: Shew_3136
symbol: Shew_3136
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: she:Shewmr4_2735 FAD linked oxidase domain protein.


ensembl_gene_id: Shew_3141
symbol: Shew_3141
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0823 ABC transporter-related protein.


ensembl_gene_id: Shew_3142
symbol: Shew_3142
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_0822 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Shew_3143
symbol: ubiX
gene_biotype: protein_coding
description:
  3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: Shew_3144
symbol: mpl
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: Shew_3148
symbol: Shew_3148
gene_biotype: protein_coding
description:
  Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR; KEGG: rso:RSc1851 putative transcription regulator protein.


ensembl_gene_id: Shew_3152
symbol: Shew_3152
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: shm:Shewmr7_3529 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family.


ensembl_gene_id: Shew_3157
symbol: Shew_3157
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sfr:Sfri_0614 twin-arginine translocation pathway signal.


ensembl_gene_id: Shew_3163
symbol: Shew_3163
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0458 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.


ensembl_gene_id: Shew_3164
symbol: Shew_3164
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0917 ABC transporter-related protein.


ensembl_gene_id: Shew_3165
symbol: Shew_3165
gene_biotype: protein_coding
description:
  TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_3054 polar amino acid ABC transporter, inner membrane subunit.


ensembl_gene_id: Shew_3166
symbol: Shew_3166
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; KEGG: son:SO1044 amino acid ABC transporter, periplasmic amino acid-binding protein.


ensembl_gene_id: Shew_3168
symbol: Shew_3168
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF541; KEGG: shm:Shewmr7_0500 protein of unknown function DUF541.


ensembl_gene_id: Shew_3170
symbol: Shew_3170
gene_biotype: protein_coding
description:
  PFAM: sodium/hydrogen exchanger; KEGG: sfr:Sfri_3583 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: Shew_3171
symbol: lgt
gene_biotype: protein_coding
description:
  Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: Shew_3172
symbol: Shew_3172
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_4664 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Shew_3173
symbol: Shew_3173
gene_biotype: protein_coding
description:
  KEGG: cps:CPS_2023 succinate-semialdehyde dehydrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Shew_3174
symbol: Shew_3174
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_4666 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3176
symbol: Shew_3176
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sfr:Sfri_3695 regulatory protein GntR, HTH.


ensembl_gene_id: Shew_3180
symbol: Shew_3180
gene_biotype: protein_coding
description:
  PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0952 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Shew_3181
symbol: Shew_3181
gene_biotype: protein_coding
description:
  PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2787 twin-arginine translocation pathway signal.


ensembl_gene_id: Shew_3186
symbol: Shew_3186
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family with amidase-like domain; PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: eca:ECA2247 Arac-family transcriptional regulator.


ensembl_gene_id: Shew_3187
symbol: Shew_3187
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.


ensembl_gene_id: Shew_3188
symbol: Shew_3188
gene_biotype: protein_coding
description:
  PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: sfr:Sfri_0574 aromatic amino acid permease.


ensembl_gene_id: Shew_3189
symbol: Shew_3189
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0016; KEGG: she:Shewmr4_3028 protein of unknown function UPF0016.


ensembl_gene_id: Shew_3192
symbol: Shew_3192
gene_biotype: protein_coding
description:
  TIGRFAM: uncharacterized domain 1 protein; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0943 uncharacterized domain 1 protein.


ensembl_gene_id: Shew_3193
symbol: Shew_3193
gene_biotype: protein_coding
description:
  PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_3033 endonuclease/exonuclease/phosphatase.


ensembl_gene_id: Shew_3194
symbol: Shew_3194
gene_biotype: protein_coding
description:
  Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sdn:Sden_3096 regulatory protein, LuxR.


ensembl_gene_id: Shew_3196
symbol: Shew_3196
gene_biotype: protein_coding
description:
  D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: sfr:Sfri_0558 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.


ensembl_gene_id: Shew_3198
symbol: Shew_3198
gene_biotype: protein_coding
description:
  PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: she:Shewmr4_0717 glycine cleavage T protein (aminomethyl transferase); Belongs to the GcvT family.


ensembl_gene_id: Shew_3199
symbol: Shew_3199
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3306 response regulator receiver modulated metal dependent phosphohydrolase.


ensembl_gene_id: Shew_3200
symbol: Shew_3200
gene_biotype: protein_coding
description:
  KEGG: son:SO0859 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_3201
symbol: Shew_3201
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_0713 ABC transporter-related protein.


ensembl_gene_id: Shew_3202
symbol: Shew_3202
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF214; KEGG: son:SO0856 putative ABC transport system permease protein.


ensembl_gene_id: Shew_3205
symbol: napD-2
gene_biotype: protein_coding
description:
  NapD family protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: Shew_3207
symbol: Shew_3207
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase subunit NapG; TIGRFAM: MauM/NapG family ferredoxin-type protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3319 MauM/NapG family ferredoxin-type protein.


ensembl_gene_id: Shew_3208
symbol: Shew_3208
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase subunit NapH; TIGRFAM: ferredoxin-type protein, NapH/MauN family; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_0702 ferredoxin-type protein, NapH/MauN family.


ensembl_gene_id: Shew_3211
symbol: Shew_3211
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: pat:Patl_0196 glutathione S-transferase-like; Belongs to the GST superfamily.


ensembl_gene_id: Shew_3213
symbol: Shew_3213
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vpa:VPA0104 putative ring-cleaving dioxygenase.


ensembl_gene_id: Shew_3215
symbol: Shew_3215
gene_biotype: protein_coding
description:
  TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein; KEGG: mes:Meso_2232 ATPase, P-type (transporting), HAD superfamily, subfamily IC.


ensembl_gene_id: Shew_3218
symbol: Shew_3218
gene_biotype: protein_coding
description:
  PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: she:Shewmr4_0696 carbamoyl-phosphate synthase L chain, ATP-binding.


ensembl_gene_id: Shew_3219
symbol: Shew_3219
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0695 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3220
symbol: Shew_3220
gene_biotype: protein_coding
description:
  Beta-lactamase; PFAM: penicillin-binding protein, transpeptidase; KEGG: shm:Shewmr7_3328 beta-lactamase.


ensembl_gene_id: Shew_3222
symbol: sprT
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT; KEGG: son:SO0834 sprT protein, putative; Belongs to the SprT family.


ensembl_gene_id: Shew_3224
symbol: Shew_3224
gene_biotype: protein_coding
description:
  Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: Shew_3225
symbol: gshB-2
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3333 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.


ensembl_gene_id: Shew_3226
symbol: Shew_3226
gene_biotype: protein_coding
description:
  PFAM: Alkaline phosphatase; KEGG: she:Shewmr4_0688 alkaline phosphatase; Belongs to the alkaline phosphatase family.


ensembl_gene_id: Shew_3227
symbol: Shew_3227
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: cps:CPS_0952 GGDEF/EAL domain protein.


ensembl_gene_id: Shew_3230
symbol: rsmC
gene_biotype: protein_coding
description:
  16S rRNA m(2)G 1207 methyltransferase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: Shew_3231
symbol: Shew_3231
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF342; KEGG: shm:Shewmr7_0674 protein of unknown function DUF342.


ensembl_gene_id: Shew_3233
symbol: Shew_3233
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: pae:PA1544 transcriptional regulator Anr.


ensembl_gene_id: Shew_3235
symbol: Shew_3235
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: mes:Meso_2223 multi-sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_3240
symbol: Shew_3240
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: dar:Daro_3108 regulatory protein, LuxR:response regulator receiver.


ensembl_gene_id: Shew_3241
symbol: Shew_3241
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: abo:ABO_2371 TonB-dependent receptor protein.


ensembl_gene_id: Shew_3244
symbol: Shew_3244
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: vpa:VP2011 tetrathionate reductase, subunit B.


ensembl_gene_id: Shew_3245
symbol: Shew_3245
gene_biotype: protein_coding
description:
  PFAM: Polysulphide reductase, NrfD; KEGG: eba:ebA1013 molybdenum enzyme of unknown function, small subunit, membrane anchor.


ensembl_gene_id: Shew_3249
symbol: Shew_3249
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO3894 sensor histidine kinase.


ensembl_gene_id: Shew_3250
symbol: Shew_3250
gene_biotype: protein_coding
description:
  Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: Shew_3251
symbol: Shew_3251
gene_biotype: protein_coding
description:
  PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: she:Shewmr4_3226 UBA/ThiF-type NAD/FAD binding protein.


ensembl_gene_id: Shew_3256
symbol: Shew_3256
gene_biotype: protein_coding
description:
  PFAM: copper resistance B precursor; KEGG: pha:PSHAb0010 copper resistance protein B [precursor] (CPx-type copper ATPase).


ensembl_gene_id: Shew_3257
symbol: Shew_3257
gene_biotype: protein_coding
description:
  TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: sde:Sde_1947 putative copper resistance transmembrane protein.


ensembl_gene_id: Shew_3258
symbol: Shew_3258
gene_biotype: protein_coding
description:
  Two component heavy metal response transcriptional regulator, winged helix family; TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pha:PSHAb0012 transcriptional activator of copper resistance (two-component regulatory system with CusS).


ensembl_gene_id: Shew_3259
symbol: Shew_3259
gene_biotype: protein_coding
description:
  Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system.


ensembl_gene_id: Shew_3261
symbol: tpm
gene_biotype: protein_coding
description:
  PFAM: thiopurine S-methyltransferase; KEGG: son:SO0582 thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.


ensembl_gene_id: Shew_3263
symbol: Shew_3263
gene_biotype: protein_coding
description:
  PFAM: protein kinase; SMART: serine/threonine protein kinase; KEGG: she:Shewmr4_0579 serine/threonine protein kinase.


ensembl_gene_id: Shew_3265
symbol: Shew_3265
gene_biotype: protein_coding
description:
  PFAM: CutA1 divalent ion tolerance protein; KEGG: shm:Shewmr7_0547 CutA1 divalent ion tolerance protein.


ensembl_gene_id: Shew_3266
symbol: dsbD
gene_biotype: protein_coding
description:
  Protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: Shew_3267
symbol: Shew_3267
gene_biotype: protein_coding
description:
  PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: shm:Shewmr7_0545 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Shew_3269
symbol: Shew_3269
gene_biotype: protein_coding
description:
  Beta-galactosidase; PFAM: glycoside hydrolase, family 42, domain 5, loop region; glycoside hydrolase family 2, immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2, TIM barrel; glycoside hydrolase family 2, sugar binding; KEGG: tma:TM1193 beta-galactosidase.


ensembl_gene_id: Shew_3270
symbol: Shew_3270
gene_biotype: protein_coding
description:
  TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pat:Patl_3683 SSS sodium solute transporter superfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Shew_3274
symbol: Shew_3274
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO0640 alcohol dehydrogenase, zinc-containing.


ensembl_gene_id: Shew_3277
symbol: alr
gene_biotype: protein_coding
description:
  Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: Shew_3278
symbol: Shew_3278
gene_biotype: protein_coding
description:
  Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: Shew_3282
symbol: rpsR
gene_biotype: protein_coding
description:
  SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: Shew_3283
symbol: Shew_3283
gene_biotype: protein_coding
description:
  Restart primosome assembly protein PriB; KEGG: sdn:Sden_0516 single-strand binding protein/primosomal replication protein N.


ensembl_gene_id: Shew_3285
symbol: Shew_3285
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF481; KEGG: she:Shewmr4_3261 protein of unknown function DUF481.


ensembl_gene_id: Shew_3288
symbol: rlmB
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 3; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.


ensembl_gene_id: Shew_3289
symbol: rnr
gene_biotype: protein_coding
description:
  RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.


ensembl_gene_id: Shew_3290
symbol: Shew_3290
gene_biotype: protein_coding
description:
  PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO3936 sodium-type flagellar protein MotX.


ensembl_gene_id: Shew_3291
symbol: purA
gene_biotype: protein_coding
description:
  Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: Shew_3293
symbol: rpsI
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S9; KEGG: shm:Shewmr7_0679 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.


ensembl_gene_id: Shew_3294
symbol: rplM
gene_biotype: protein_coding
description:
  LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: Shew_3296
symbol: Shew_3296
gene_biotype: protein_coding
description:
  TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_3271 protease Do; Belongs to the peptidase S1C family.


ensembl_gene_id: Shew_3297
symbol: Shew_3297
gene_biotype: protein_coding
description:
  TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO3943 protease DegS.


ensembl_gene_id: Shew_3298
symbol: murA
gene_biotype: protein_coding
description:
  UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: Shew_3299
symbol: Shew_3299
gene_biotype: protein_coding
description:
  PFAM: BolA family protein; KEGG: shm:Shewmr7_3338 BolA family protein; Belongs to the BolA/IbaG family.


ensembl_gene_id: Shew_3300
symbol: Shew_3300
gene_biotype: protein_coding
description:
  PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: shm:Shewmr7_3339 SpoIIAA family protein.


ensembl_gene_id: Shew_3302
symbol: Shew_3302
gene_biotype: protein_coding
description:
  PFAM: Mammalian cell entry related domain protein; KEGG: shm:Shewmr7_3341 mammalian cell entry related domain protein.


ensembl_gene_id: Shew_3304
symbol: Shew_3304
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3343 ABC transporter-related protein.


ensembl_gene_id: Shew_3305
symbol: Shew_3305
gene_biotype: protein_coding
description:
  TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: sdn:Sden_0495 K+-dependent Na+/Ca+ exchanger related-protein.


ensembl_gene_id: Shew_3306
symbol: Shew_3306
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3344 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS).


ensembl_gene_id: Shew_3307
symbol: Shew_3307
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: Shew_3308
symbol: lptC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1239; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: Shew_3309
symbol: lptA
gene_biotype: protein_coding
description:
  OstA family protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: Shew_3310
symbol: Shew_3310
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3348 ABC transporter-related protein.


ensembl_gene_id: Shew_3311
symbol: Shew_3311
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: Shew_3312
symbol: Shew_3312
gene_biotype: protein_coding
description:
  TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_3350 sigma 54 modulation protein/ribosomal protein S30EA.


ensembl_gene_id: Shew_3313
symbol: Shew_3313
gene_biotype: protein_coding
description:
  TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: shm:Shewmr7_3351 PTS IIA-like nitrogen-regulatory protein PtsN.


ensembl_gene_id: Shew_3315
symbol: Shew_3315
gene_biotype: protein_coding
description:
  TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: she:Shewmr4_0669 phosphocarrier, HPr family.


ensembl_gene_id: Shew_3317
symbol: Shew_3317
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: vpa:VP1983 putaive two-component response regulator.


ensembl_gene_id: Shew_3318
symbol: Shew_3318
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: vpa:VP1984 putative two-component sensor.


ensembl_gene_id: Shew_3322
symbol: Shew_3322
gene_biotype: protein_coding
description:
  TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: ppr:PBPRB1503 hypothetical membrane protein.


ensembl_gene_id: Shew_3325
symbol: Shew_3325
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: pha:PSHAa1259 transport protein of the major facilitator.


ensembl_gene_id: Shew_3326
symbol: Shew_3326
gene_biotype: protein_coding
description:
  PFAM: sodium/hydrogen exchanger; KEGG: hch:HCH_01176 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain.


ensembl_gene_id: Shew_3327
symbol: Shew_3327
gene_biotype: protein_coding
description:
  PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: shm:Shewmr7_3492 RNA-metabolising metallo-beta-lactamase.


ensembl_gene_id: Shew_3328
symbol: Shew_3328
gene_biotype: protein_coding
description:
  PFAM: Ig domain protein, group 2 domain protein; Kelch repeat-containing protein; KEGG: hch:HCH_00094 cell wall surface anchor family protein.


ensembl_gene_id: Shew_3329
symbol: Shew_3329
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: shm:Shewmr7_3362 diguanylate cyclase/phosphodiesterase with GAF sensor.


ensembl_gene_id: Shew_3330
symbol: Shew_3330
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4425 GGDEF family protein.


ensembl_gene_id: Shew_3331
symbol: Shew_3331
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp; KEGG: sdn:Sden_3444 cyclic nucleotide-binding.


ensembl_gene_id: Shew_3333
symbol: Shew_3333
gene_biotype: protein_coding
description:
  PFAM: electron transport protein SCO1/SenC; KEGG: sdn:Sden_3480 electron transport protein SCO1/SenC.


ensembl_gene_id: Shew_3335
symbol: Shew_3335
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_3482 nitrite reductase, copper containing; TIGRFAM: nitrite reductase, copper-containing; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3; Belongs to the multicopper oxidase family.


ensembl_gene_id: Shew_3337
symbol: Shew_3337
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6, transmembrane; KEGG: sfr:Sfri_3644 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Shew_3340
symbol: Shew_3340
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_0484 TonB-dependent receptor.


ensembl_gene_id: Shew_3341
symbol: Shew_3341
gene_biotype: protein_coding
description:
  Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: vfi:VF2362 GGDEF family protein.


ensembl_gene_id: Shew_3342
symbol: Shew_3342
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; helix-turn-helix, Fis-type; KEGG: she:Shewmr4_3529 response regulator receiver protein.


ensembl_gene_id: Shew_3343
symbol: Shew_3343
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3530 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_3345
symbol: Shew_3345
gene_biotype: protein_coding
description:
  Diacylglycerol kinase, catalytic region; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.


ensembl_gene_id: Shew_3354
symbol: Shew_3354
gene_biotype: protein_coding
description:
  PFAM: aminotransferase, class V; beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: cps:CPS_0838 aminotransferase, class V.


ensembl_gene_id: Shew_3356
symbol: Shew_3356
gene_biotype: protein_coding
description:
  TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3513 heavy metal efflux pump, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_3357
symbol: Shew_3357
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sdn:Sden_0575 secretion protein HlyD.


ensembl_gene_id: Shew_3362
symbol: Shew_3362
gene_biotype: protein_coding
description:
  PFAM: Class I peptide chain release factor; KEGG: shm:Shewmr7_3519 class I peptide chain release factor.


ensembl_gene_id: Shew_3363
symbol: aroQ
gene_biotype: protein_coding
description:
  3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: Shew_3364
symbol: Shew_3364
gene_biotype: protein_coding
description:
  Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Shew_3365
symbol: Shew_3365
gene_biotype: protein_coding
description:
  acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: Shew_3366
symbol: Shew_3366
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; PFAM: histidine kinase, HAMP region domain protein; SMART: extracellular solute-binding protein, family 3; metal-dependent phosphohydrolase, HD region; KEGG: vvy:VV1527 hypothetical protein.


ensembl_gene_id: Shew_3370
symbol: rraA
gene_biotype: protein_coding
description:
  Protein of unknown function 1935; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: Shew_3372
symbol: Shew_3372
gene_biotype: protein_coding
description:
  PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: she:Shewmr4_3550 arginase/agmatinase/formiminoglutamase; Belongs to the arginase family.


ensembl_gene_id: Shew_3373
symbol: ubiE
gene_biotype: protein_coding
description:
  Demethylmenaquinone methyltransferase / 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: Shew_3374
symbol: Shew_3374
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1243; KEGG: she:Shewmr4_3552 protein of unknown function DUF1243.


ensembl_gene_id: Shew_3375
symbol: ubiB
gene_biotype: protein_coding
description:
  2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: Shew_3376
symbol: tatA
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatA/E family subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: Shew_3377
symbol: tatB
gene_biotype: protein_coding
description:
  Twin-arginine translocation protein, TatB subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: Shew_3378
symbol: tatC
gene_biotype: protein_coding
description:
  Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: Shew_3380
symbol: Shew_3380
gene_biotype: protein_coding
description:
  Sec-independent protein translocase TatD; PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_0398 TatD-related deoxyribonuclease.


ensembl_gene_id: Shew_3381
symbol: Shew_3381
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region; KEGG: son:SO4207 GGDEF domain protein.


ensembl_gene_id: Shew_3382
symbol: Shew_3382
gene_biotype: protein_coding
description:
  Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: she:Shewmr4_3560 porphobilinogen synthase; Belongs to the ALAD family.


ensembl_gene_id: Shew_3384
symbol: ubiA
gene_biotype: protein_coding
description:
  4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: Shew_3390
symbol: Shew_3390
gene_biotype: protein_coding
description:
  Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: Shew_3392
symbol: Shew_3392
gene_biotype: protein_coding
description:
  PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: shm:Shewmr7_0445 diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.


ensembl_gene_id: Shew_3395
symbol: Shew_3395
gene_biotype: protein_coding
description:
  PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: shm:Shewmr7_3501 radical SAM domain protein.


ensembl_gene_id: Shew_3399
symbol: Shew_3399
gene_biotype: protein_coding
description:
  PFAM: FMN-binding domain protein; KEGG: ppr:PBPRB0846 hypothetical NosR, regulator of nitric oxide reductase transcription.


ensembl_gene_id: Shew_3400
symbol: nosZ
gene_biotype: protein_coding
description:
  Nitrous-oxide reductase; Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide; In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.


ensembl_gene_id: Shew_3401
symbol: Shew_3401
gene_biotype: protein_coding
description:
  PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: sdn:Sden_2218 periplasmic copper-binding.


ensembl_gene_id: Shew_3402
symbol: Shew_3402
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sdn:Sden_2217 ABC transporter-related protein.


ensembl_gene_id: Shew_3405
symbol: Shew_3405
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO0525 drug resistance transporter, EmrB/QacA family protein.


ensembl_gene_id: Shew_3406
symbol: Shew_3406
gene_biotype: protein_coding
description:
  PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3509 secretion protein HlyD family protein.


ensembl_gene_id: Shew_3407
symbol: Shew_3407
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0523 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3411
symbol: Shew_3411
gene_biotype: protein_coding
description:
  Transcriptional regulator, MerR family; TIGRFAM: Zn(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: she:Shewmr4_0446 transcriptional regulator, MerR family.


ensembl_gene_id: Shew_3412
symbol: purH
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_0493 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme, formylation region.


ensembl_gene_id: Shew_3413
symbol: purD
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_0492 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family.


ensembl_gene_id: Shew_3415
symbol: Shew_3415
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_3588 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Shew_3416
symbol: Shew_3416
gene_biotype: protein_coding
description:
  TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; KEGG: son:SO0437 sensory box protein.


ensembl_gene_id: Shew_3419
symbol: Shew_3419
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfr:Sfri_0485 two component transcriptional regulator, winged helix family protein.


ensembl_gene_id: Shew_3420
symbol: Shew_3420
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sfr:Sfri_0484 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_3422
symbol: hemE
gene_biotype: protein_coding
description:
  Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: Shew_3423
symbol: Shew_3423
gene_biotype: protein_coding
description:
  PFAM: regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ; KEGG: shm:Shewmr7_3591 regulator of RpoD, Rsd/AlgQ; Belongs to the Rsd/AlgQ family.


ensembl_gene_id: Shew_3424
symbol: Shew_3424
gene_biotype: protein_coding
description:
  Aconitase; PFAM: aconitate hydratase domain protein; aconitate hydratase 2; KEGG: shm:Shewmr7_3592 aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.


ensembl_gene_id: Shew_3425
symbol: Shew_3425
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdn:Sden_3378 HAD-superfamily hydrolase subfamily IA, variant 3.


ensembl_gene_id: Shew_3426
symbol: Shew_3426
gene_biotype: protein_coding
description:
  Endothelin-converting enzyme 1; PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_0433 endothelin-converting enzyme 1.


ensembl_gene_id: Shew_3428
symbol: Shew_3428
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: son:SO0427 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_3429
symbol: Shew_3429
gene_biotype: protein_coding
description:
  TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: shm:Shewmr7_3597 dihydrolipoamide dehydrogenase.


ensembl_gene_id: Shew_3430
symbol: Shew_3430
gene_biotype: protein_coding
description:
  Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Shew_3431
symbol: Shew_3431
gene_biotype: protein_coding
description:
  2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: Shew_3432
symbol: Shew_3432
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_3600 regulatory protein GntR, HTH.


ensembl_gene_id: Shew_3434
symbol: Shew_3434
gene_biotype: protein_coding
description:
  PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: sfr:Sfri_3780 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD.


ensembl_gene_id: Shew_3435
symbol: Shew_3435
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3603 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.


ensembl_gene_id: Shew_3438
symbol: Shew_3438
gene_biotype: protein_coding
description:
  TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: shm:Shewmr7_3605 type IV-A pilus assembly ATPase PilB.


ensembl_gene_id: Shew_3440
symbol: Shew_3440
gene_biotype: protein_coding
description:
  Prepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.


ensembl_gene_id: Shew_3441
symbol: coaE
gene_biotype: protein_coding
description:
  dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: Shew_3442
symbol: zapD
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1342; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: Shew_3443
symbol: yacG
gene_biotype: protein_coding
description:
  Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: Shew_3445
symbol: secA
gene_biotype: protein_coding
description:
  Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.


ensembl_gene_id: Shew_3448
symbol: lpxC
gene_biotype: protein_coding
description:
  UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: Shew_3449
symbol: ftsZ
gene_biotype: protein_coding
description:
  Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: Shew_3450
symbol: ftsA
gene_biotype: protein_coding
description:
  Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: Shew_3451
symbol: ftsQ
gene_biotype: protein_coding
description:
  Polypeptide-transport-associated domain protein, FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: Shew_3453
symbol: murG
gene_biotype: protein_coding
description:
  Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: Shew_3454
symbol: ftsW
gene_biotype: protein_coding
description:
  Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: Shew_3455
symbol: murD
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: Shew_3456
symbol: mraY
gene_biotype: protein_coding
description:
  Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: Shew_3457
symbol: murF
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: Shew_3458
symbol: murE
gene_biotype: protein_coding
description:
  UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.


ensembl_gene_id: Shew_3459
symbol: ftsI
gene_biotype: protein_coding
description:
  Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: Shew_3460
symbol: ftsL
gene_biotype: protein_coding
description:
  Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: Shew_3461
symbol: rsmH
gene_biotype: protein_coding
description:
  S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: Shew_3462
symbol: mraZ
gene_biotype: protein_coding
description:
  TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: shm:Shewmr7_0377 MraZ protein; Belongs to the MraZ family.


ensembl_gene_id: Shew_3466
symbol: glpK
gene_biotype: protein_coding
description:
  Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.


ensembl_gene_id: Shew_3468
symbol: Shew_3468
gene_biotype: protein_coding
description:
  PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: she:Shewmr4_3584 membrane protein involved in aromatic hydrocarbon degradation.


ensembl_gene_id: Shew_3469
symbol: leuD
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: Shew_3470
symbol: leuC
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: Shew_3471
symbol: leuB
gene_biotype: protein_coding
description:
  3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: Shew_3472
symbol: leuA
gene_biotype: protein_coding
description:
  2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: Shew_3474
symbol: Shew_3474
gene_biotype: protein_coding
description:
  KEGG: son:SO4241 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like.


ensembl_gene_id: Shew_3475
symbol: Shew_3475
gene_biotype: protein_coding
description:
  TIGRFAM: uncharacterized domain 1 protein; PFAM: thioesterase superfamily protein; KEGG: she:Shewmr4_3591 uncharacterized domain 1 protein.


ensembl_gene_id: Shew_3476
symbol: Shew_3476
gene_biotype: protein_coding
description:
  TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4243 rarD protein.


ensembl_gene_id: Shew_3478
symbol: argA
gene_biotype: protein_coding
description:
  N-acetylglutamate synthase; KEGG: son:SO4245 amino-acid acetyltransferase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; Belongs to the acetyltransferase family. ArgA subfamily.


ensembl_gene_id: Shew_3479
symbol: rpmG
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L33; KEGG: shm:Shewmr7_0361 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.


ensembl_gene_id: Shew_3480
symbol: rpmB
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L28; KEGG: shm:Shewmr7_0360 ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.


ensembl_gene_id: Shew_3481
symbol: Shew_3481
gene_biotype: protein_coding
description:
  PFAM: DNA repair protein RadC; KEGG: sfr:Sfri_3828 DNA repair protein RadC; Belongs to the UPF0758 family.


ensembl_gene_id: Shew_3482
symbol: Shew_3482
gene_biotype: protein_coding
description:
  Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: Shew_3483
symbol: dut
gene_biotype: protein_coding
description:
  Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: Shew_3484
symbol: slmA
gene_biotype: protein_coding
description:
  Cell division inhibitor SlmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: Shew_3485
symbol: Shew_3485
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; dienelactone hydrolase; KEGG: son:SO4252 prolyl oligopeptidase family protein.


ensembl_gene_id: Shew_3487
symbol: pyrE
gene_biotype: protein_coding
description:
  Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: Shew_3488
symbol: rph
gene_biotype: protein_coding
description:
  RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: Shew_3489
symbol: Shew_3489
gene_biotype: protein_coding
description:
  PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732; KEGG: she:Shewmr4_3605 hypothetical protein.


ensembl_gene_id: Shew_3490
symbol: Shew_3490
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_0337 transcriptional regulator, XRE family.


ensembl_gene_id: Shew_3498
symbol: rpoZ
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: Shew_3500
symbol: Shew_3500
gene_biotype: protein_coding
description:
  TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sdn:Sden_3436 YjgF-like protein.


ensembl_gene_id: Shew_3501
symbol: trmH
gene_biotype: protein_coding
description:
  tRNA guanosine-2'-O-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: Shew_3503
symbol: Shew_3503
gene_biotype: protein_coding
description:
  TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: shm:Shewmr7_0325 Na+/Ca+ antiporter, CaCA family.


ensembl_gene_id: Shew_3504
symbol: Shew_3504
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_0324 TPR repeat-containing protein.


ensembl_gene_id: Shew_3505
symbol: Shew_3505
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shm:Shewmr7_0323 putative signal transduction histidine kinase.


ensembl_gene_id: Shew_3506
symbol: Shew_3506
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein; Sigma-70, region 4 type 2; KEGG: son:SO0351 DNA-binding response regulator, LuxR family.


ensembl_gene_id: Shew_3507
symbol: recG
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: Shew_3510
symbol: Shew_3510
gene_biotype: protein_coding
description:
  PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_3675 phospholipid/glycerol acyltransferase.


ensembl_gene_id: Shew_3512
symbol: acpP-2
gene_biotype: protein_coding
description:
  Phosphopantetheine-binding; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.


ensembl_gene_id: Shew_3515
symbol: Shew_3515
gene_biotype: protein_coding
description:
  PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: she:Shewmr4_0346 thioester dehydrase family protein.


ensembl_gene_id: Shew_3516
symbol: Shew_3516
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase, family 2; lipid A biosynthesis acyltransferase; KEGG: she:Shewmr4_0345 glycosyl transferase, family 2.


ensembl_gene_id: Shew_3521
symbol: Shew_3521
gene_biotype: protein_coding
description:
  Tryptophan halogenase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3686 monooxygenase, FAD-binding protein.


ensembl_gene_id: Shew_3523
symbol: Shew_3523
gene_biotype: protein_coding
description:
  PFAM: beta-ketoacyl synthase; KEGG: shm:Shewmr7_3688 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Shew_3524
symbol: Shew_3524
gene_biotype: protein_coding
description:
  PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: sfr:Sfri_0339 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ.


ensembl_gene_id: Shew_3525
symbol: Shew_3525
gene_biotype: protein_coding
description:
  TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase, putative; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_3690 3-oxoacyl-(acyl-carrier-protein) reductase, putative.


ensembl_gene_id: Shew_3526
symbol: Shew_3526
gene_biotype: protein_coding
description:
  PFAM: beta-ketoacyl synthase; KEGG: shm:Shewmr7_3691 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Shew_3529
symbol: azoR
gene_biotype: protein_coding
description:
  (Acyl-carrier-protein) phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: Shew_3530
symbol: plsB
gene_biotype: protein_coding
description:
  PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_3861 glycerol-3-phosphate O-acyltransferase; Belongs to the GPAT/DAPAT family.


ensembl_gene_id: Shew_3531
symbol: Shew_3531
gene_biotype: protein_coding
description:
  TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: sfr:Sfri_0262 aromatic amino acid transporter.


ensembl_gene_id: Shew_3533
symbol: Shew_3533
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_0263 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Shew_3534
symbol: Shew_3534
gene_biotype: protein_coding
description:
  TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_3783 heavy metal efflux pump, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_3535
symbol: Shew_3535
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: she:Shewmr4_3782 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_3542
symbol: dtd
gene_biotype: protein_coding
description:
  D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: Shew_3544
symbol: Shew_3544
gene_biotype: protein_coding
description:
  PFAM: alpha/beta hydrolase fold; KEGG: son:SO4400 proline iminopeptidase, putative; Belongs to the peptidase S33 family.


ensembl_gene_id: Shew_3545
symbol: Shew_3545
gene_biotype: protein_coding
description:
  tRNA-processing RNAse BN; TIGRFAM: putative ribonuclease BN; PFAM: ribonuclease BN; KEGG: she:Shewmr4_0316 putative ribonuclease BN.


ensembl_gene_id: Shew_3549
symbol: Shew_3549
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sfr:Sfri_0773 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_3550
symbol: Shew_3550
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: hch:HCH_02929 AraC-type DNA-binding domain-containing protein.


ensembl_gene_id: Shew_3551
symbol: Shew_3551
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: vpa:VPA1016 multidrug resistance protein D.


ensembl_gene_id: Shew_3553
symbol: Shew_3553
gene_biotype: protein_coding
description:
  TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: shm:Shewmr7_3718 GTP-binding protein TypA.


ensembl_gene_id: Shew_3554
symbol: Shew_3554
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3719 glutamine synthetase, type I; TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region; glutamine synthetase, beta-Grasp.


ensembl_gene_id: Shew_3558
symbol: Shew_3558
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, AsnC/Lrp family; Helix-turn-helix, type 11 domain protein; KEGG: pha:PSHAa0053 transcriptional regulator.


ensembl_gene_id: Shew_3560
symbol: Shew_3560
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3763 signal transduction histidine kinase, nitrogen specific, NtrB.


ensembl_gene_id: Shew_3561
symbol: ntrC
gene_biotype: protein_coding
description:
  Nitrogen metabolism transcriptional regulator, NtrC, Fis family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: Shew_3562
symbol: Shew_3562
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0843 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3565
symbol: Shew_3565
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: sdn:Sden_2206 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_3567
symbol: Shew_3567
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; KEGG: sdn:Sden_2204 regulatory protein, TetR.


ensembl_gene_id: Shew_3568
symbol: Shew_3568
gene_biotype: protein_coding
description:
  TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_3767 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.


ensembl_gene_id: Shew_3569
symbol: Shew_3569
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function, Spy-related; KEGG: she:Shewmr4_0253 protein of unknown function, Spy-related.


ensembl_gene_id: Shew_3570
symbol: Shew_3570
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfr:Sfri_0311 two component transcriptional regulator, winged helix family protein.


ensembl_gene_id: Shew_3571
symbol: Shew_3571
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4478 sensor protein CpxA.


ensembl_gene_id: Shew_3572
symbol: Shew_3572
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: she:Shewmr4_2154 alcohol dehydrogenase, zinc-binding domain protein.


ensembl_gene_id: Shew_3573
symbol: Shew_3573
gene_biotype: protein_coding
description:
  GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_3771 GAF modulated sigma54 specific transcriptional regulator, fis family.


ensembl_gene_id: Shew_3574
symbol: Shew_3574
gene_biotype: protein_coding
description:
  PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3772 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Shew_3577
symbol: trmL
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 2; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: Shew_3583
symbol: Shew_3583
gene_biotype: protein_coding
description:
  PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3819 methyltransferase type 11.


ensembl_gene_id: Shew_3585
symbol: Shew_3585
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: son:SO4552 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold domain protein; SMART: PAS domain containing protein.


ensembl_gene_id: Shew_3588
symbol: Shew_3588
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3750 drug resistance transporter, Bcr/CflA subfamily.


ensembl_gene_id: Shew_3589
symbol: Shew_3589
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4556 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3595
symbol: Shew_3595
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1332; KEGG: she:Shewmr4_3757 protein of unknown function DUF1332.


ensembl_gene_id: Shew_3597
symbol: Shew_3597
gene_biotype: protein_coding
description:
  PFAM: amino acid permease-associated region; KEGG: sdn:Sden_3500 amino acid permease-associated region.


ensembl_gene_id: Shew_3598
symbol: Shew_3598
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, AsnC/Lrp family; regulatory protein, ArsR; KEGG: shm:Shewmr7_3834 transcriptional regulator, AsnC family.


ensembl_gene_id: Shew_3599
symbol: menD
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).


ensembl_gene_id: Shew_3600
symbol: menH
gene_biotype: protein_coding
description:
  Alpha/beta hydrolase fold; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: Shew_3602
symbol: Shew_3602
gene_biotype: protein_coding
description:
  TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_3770 O-succinylbenzoate-CoA ligase.


ensembl_gene_id: Shew_3603
symbol: rpoH
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: Shew_3604
symbol: Shew_3604
gene_biotype: protein_coding
description:
  Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: Shew_3605
symbol: ftsE
gene_biotype: protein_coding
description:
  Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.


ensembl_gene_id: Shew_3606
symbol: ftsY
gene_biotype: protein_coding
description:
  Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: Shew_3607
symbol: Shew_3607
gene_biotype: protein_coding
description:
  Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: Shew_3608
symbol: Shew_3608
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1145; KEGG: shm:Shewmr7_3849 protein of unknown function DUF1145.


ensembl_gene_id: Shew_3609
symbol: Shew_3609
gene_biotype: protein_coding
description:
  PFAM: type II secretion system protein N; KEGG: shm:Shewmr7_0161 type II secretion system protein N.


ensembl_gene_id: Shew_3610
symbol: Shew_3610
gene_biotype: protein_coding
description:
  General secretion pathway M protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Shew_3611
symbol: Shew_3611
gene_biotype: protein_coding
description:
  General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Shew_3612
symbol: Shew_3612
gene_biotype: protein_coding
description:
  PFAM: General secretion pathway protein K; KEGG: shm:Shewmr7_0158 general secretion pathway protein K.


ensembl_gene_id: Shew_3613
symbol: Shew_3613
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein J; KEGG: she:Shewmr4_0162 general secretion pathway protein J.


ensembl_gene_id: Shew_3614
symbol: Shew_3614
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: shm:Shewmr7_0156 general secretion pathway protein I.


ensembl_gene_id: Shew_3616
symbol: Shew_3616
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: shm:Shewmr7_0154 general secretion pathway protein G.


ensembl_gene_id: Shew_3617
symbol: Shew_3617
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: sfr:Sfri_0107 general secretion pathway protein F.


ensembl_gene_id: Shew_3618
symbol: Shew_3618
gene_biotype: protein_coding
description:
  Type II secretion system protein E (GspE); Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.


ensembl_gene_id: Shew_3619
symbol: Shew_3619
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: shm:Shewmr7_0151 general secretion pathway protein D.


ensembl_gene_id: Shew_3620
symbol: Shew_3620
gene_biotype: protein_coding
description:
  TIGRFAM: general secretion pathway protein C; KEGG: she:Shewmr4_0155 general secretion pathway protein C.


ensembl_gene_id: Shew_3621
symbol: Shew_3621
gene_biotype: protein_coding
description:
  PFAM: RNA-binding S4 domain protein; KEGG: shm:Shewmr7_0149 RNA-binding S4 domain protein; Belongs to the HSP15 family.


ensembl_gene_id: Shew_3622
symbol: hslO
gene_biotype: protein_coding
description:
  Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: Shew_3623
symbol: pckA
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: Shew_3625
symbol: Shew_3625
gene_biotype: protein_coding
description:
  PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0147 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Shew_3627
symbol: Shew_3627
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: ccr:CC2232 transcriptional regulator, Cro/CI family.


ensembl_gene_id: Shew_3628
symbol: Shew_3628
gene_biotype: protein_coding
description:
  PFAM: MgtC/SapB transporter; KEGG: ilo:IL2442 uncharacterized conserved membrane protein, SapB/MtgC family.


ensembl_gene_id: Shew_3630
symbol: bioH
gene_biotype: protein_coding
description:
  bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: Shew_3634
symbol: Shew_3634
gene_biotype: protein_coding
description:
  PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: son:SO4629 hypothetical protein.


ensembl_gene_id: Shew_3635
symbol: Shew_3635
gene_biotype: protein_coding
description:
  PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: sdn:Sden_1376 thiamine pyrophosphate enzyme-like TPP binding region; Belongs to the TPP enzyme family.


ensembl_gene_id: Shew_3636
symbol: greB
gene_biotype: protein_coding
description:
  Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: Shew_3637
symbol: Shew_3637
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3902 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_3638
symbol: Shew_3638
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3903 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_3639
symbol: Shew_3639
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3904 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_3641
symbol: Shew_3641
gene_biotype: protein_coding
description:
  Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.


ensembl_gene_id: Shew_3647
symbol: rsmJ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF548; Specifically methylates the guanosine in position 1516 of 16S rRNA.


ensembl_gene_id: Shew_3648
symbol: rlmJ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF519; Specifically methylates the adenine in position 2030 of 23S rRNA.


ensembl_gene_id: Shew_3655
symbol: Shew_3655
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sde:Sde_2875 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3656
symbol: Shew_3656
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_2561 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Shew_3660
symbol: Shew_3660
gene_biotype: protein_coding
description:
  TIGRFAM: glutathione-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: she:Shewmr4_3845 glutathione-disulfide reductase.


ensembl_gene_id: Shew_3664
symbol: rimK
gene_biotype: protein_coding
description:
  SSU ribosomal protein S6P modification protein; TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: vpa:VPA0173 ribosomal protein S6 modification protein.


ensembl_gene_id: Shew_3670
symbol: Shew_3670
gene_biotype: protein_coding
description:
  PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3954 metal dependent phosphohydrolase.


ensembl_gene_id: Shew_3675
symbol: Shew_3675
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4712 ABC transporter, ATP-binding protein, putative.


ensembl_gene_id: Shew_3676
symbol: Shew_3676
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3960 TonB-dependent receptor, plug.


ensembl_gene_id: Shew_3679
symbol: Shew_3679
gene_biotype: protein_coding
description:
  Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: Shew_3681
symbol: Shew_3681
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3872 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_3682
symbol: Shew_3682
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_3966 two component, sigma54 specific, transcriptional regulator, fis family.


ensembl_gene_id: Shew_3684
symbol: Shew_3684
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3968 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Shew_3685
symbol: Shew_3685
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4721 ABC transporter, ATP-binding protein.


ensembl_gene_id: Shew_3686
symbol: mobA
gene_biotype: protein_coding
description:
  Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: Shew_3687
symbol: Shew_3687
gene_biotype: protein_coding
description:
  Molybdopterin-guanine dinucleotide biosynthesis protein B; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: Shew_3688
symbol: moaA-2
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: Shew_3690
symbol: mutM
gene_biotype: protein_coding
description:
  Formamidopyrimidine-DNA glycosylase / DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: Shew_3692
symbol: coaD
gene_biotype: protein_coding
description:
  Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: Shew_3694
symbol: hldD
gene_biotype: protein_coding
description:
  ADP-glyceromanno-heptose 6-epimerase precursor; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: Shew_3695
symbol: Shew_3695
gene_biotype: protein_coding
description:
  TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: sfr:Sfri_3930 cytidyltransferase-related domain protein.


ensembl_gene_id: Shew_3696
symbol: Shew_3696
gene_biotype: protein_coding
description:
  PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: sfr:Sfri_3931 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase.


ensembl_gene_id: Shew_3697
symbol: Shew_3697
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase, family 9; KEGG: sfr:Sfri_3932 ADP-heptose:LPS heptosyltransferase-like protein.


ensembl_gene_id: Shew_3704
symbol: Shew_3704
gene_biotype: protein_coding
description:
  TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: pfo:Pfl_0701 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: Shew_3706
symbol: kdkA
gene_biotype: protein_coding
description:
  Lipopolysaccharide kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.


ensembl_gene_id: Shew_3707
symbol: Shew_3707
gene_biotype: protein_coding
description:
  Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: Shew_3708
symbol: Shew_3708
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; KEGG: sdn:Sden_3614 regulatory protein, TetR.


ensembl_gene_id: Shew_3709
symbol: kbl
gene_biotype: protein_coding
description:
  2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.


ensembl_gene_id: Shew_3710
symbol: tdh
gene_biotype: protein_coding
description:
  L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: Shew_3711
symbol: Shew_3711
gene_biotype: protein_coding
description:
  Rhodanese domain protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: Shew_3713
symbol: Shew_3713
gene_biotype: protein_coding
description:
  ThiJ/PfpI domain protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: Shew_3714
symbol: polA
gene_biotype: protein_coding
description:
  DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: Shew_3715
symbol: engB
gene_biotype: protein_coding
description:
  Cell division checkpoint GTPase YihA; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: Shew_3718
symbol: yihI
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: Shew_3720
symbol: Shew_3720
gene_biotype: protein_coding
description:
  KEGG: son:SO4730 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: Shew_3721
symbol: add
gene_biotype: protein_coding
description:
  KEGG: son:SO4731 adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: Shew_3724
symbol: Shew_3724
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_0038 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_3727
symbol: aroE
gene_biotype: protein_coding
description:
  Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: Shew_3729
symbol: hemF
gene_biotype: protein_coding
description:
  Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: Shew_3730
symbol: tsaC
gene_biotype: protein_coding
description:
  Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: Shew_3731
symbol: Shew_3731
gene_biotype: protein_coding
description:
  PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: shm:Shewmr7_0031 DNA topoisomerase, type IA, zn finger domain protein.


ensembl_gene_id: Shew_3732
symbol: Shew_3732
gene_biotype: protein_coding
description:
  PFAM: Peptidase M9A, collagenase C-terminal domain protein; KEGG: cps:CPS_2237 microbial collagenase.


ensembl_gene_id: Shew_3733
symbol: smg
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF494; KEGG: sfr:Sfri_0027 protein of unknown function DUF494; Belongs to the Smg family.


ensembl_gene_id: Shew_3734
symbol: Shew_3734
gene_biotype: protein_coding
description:
  TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: son:SO0034 DNA processing protein DprA, putative.


ensembl_gene_id: Shew_3737
symbol: fmt
gene_biotype: protein_coding
description:
  methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: Shew_3741
symbol: rlmF
gene_biotype: protein_coding
description:
  Protein of unknown function DUF890; Specifically methylates the adenine in position 1618 of 23S rRNA.


ensembl_gene_id: Shew_3743
symbol: ubiC
gene_biotype: protein_coding
description:
  Chorismate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.


ensembl_gene_id: Shew_3744
symbol: Shew_3744
gene_biotype: protein_coding
description:
  PFAM: PKD domain containing protein; peptidase M6, immune inhibitor A; KEGG: sfr:Sfri_0047 peptidase M6, immune inhibitor A.


ensembl_gene_id: Shew_3746
symbol: Shew_3746
gene_biotype: protein_coding
description:
  PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO0129 conserved hypothetical protein TIGR00427.


ensembl_gene_id: Shew_3748
symbol: Shew_3748
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF833; KEGG: she:Shewmr4_0121 protein of unknown function DUF833.


ensembl_gene_id: Shew_3750
symbol: Shew_3750
gene_biotype: protein_coding
description:
  PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_0119 phospholipid/glycerol acyltransferase.


ensembl_gene_id: Shew_3751
symbol: Shew_3751
gene_biotype: protein_coding
description:
  PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_0113 lysine exporter protein (LysE/YggA).


ensembl_gene_id: Shew_3756
symbol: hutH
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_0095 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase.


ensembl_gene_id: Shew_3758
symbol: Shew_3758
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: she:Shewmr4_0098 transcriptional regulator, histidine utilization repressor, GntR family.


ensembl_gene_id: Shew_3759
symbol: hutI
gene_biotype: protein_coding
description:
  Imidazolonepropionase; KEGG: shm:Shewmr7_0092 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family.


ensembl_gene_id: Shew_3766
symbol: Shew_3766
gene_biotype: protein_coding
description:
  TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3951 heavy metal efflux pump, CzcA family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_3771
symbol: mtnC
gene_biotype: protein_coding
description:
  2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.


ensembl_gene_id: Shew_3776
symbol: Shew_3776
gene_biotype: protein_coding
description:
  PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_0076 AMP-dependent synthetase and ligase.


ensembl_gene_id: Shew_3778
symbol: Shew_3778
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0074 ABC transporter-related protein.


ensembl_gene_id: Shew_3779
symbol: Shew_3779
gene_biotype: protein_coding
description:
  PFAM: regulatory protein GntR, HTH; KEGG: sfr:Sfri_3976 transcriptional regulator, GntR family protein.


ensembl_gene_id: Shew_3780
symbol: Shew_3780
gene_biotype: protein_coding
description:
  TAP domain protein; PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: son:SO0071 hydrolase, alpha/beta hydrolase fold family.


ensembl_gene_id: Shew_3781
symbol: Shew_3781
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO0070 ATP-binding transport protein NatA.


ensembl_gene_id: Shew_3785
symbol: Shew_3785
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family with amidase-like domain; PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: shm:Shewmr7_0068 transcriptional regulator, AraC family.


ensembl_gene_id: Shew_3787
symbol: Shew_3787
gene_biotype: protein_coding
description:
  TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; KEGG: shm:Shewmr7_0066 molybdenum cofactor synthesis domain.


ensembl_gene_id: Shew_3788
symbol: Shew_3788
gene_biotype: protein_coding
description:
  Hpt sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; KEGG: hch:HCH_00809 signal transduction histidine kinase.


ensembl_gene_id: Shew_3790
symbol: Shew_3790
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: tdn:Tmden_0218 diguanylate cyclase (GGDEF domain).


ensembl_gene_id: Shew_3797
symbol: Shew_3797
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: vpa:VPA1191 putative multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_3798
symbol: Shew_3798
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rme:Rmet_0510 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_3802
symbol: Shew_3802
gene_biotype: protein_coding
description:
  HI0933 family protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0049 HI0933 family protein.


ensembl_gene_id: Shew_3803
symbol: gpsA
gene_biotype: protein_coding
description:
  PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: son:SO0053 glycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.


ensembl_gene_id: Shew_3804
symbol: secB
gene_biotype: protein_coding
description:
  Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: Shew_3806
symbol: gpmI
gene_biotype: protein_coding
description:
  Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.


ensembl_gene_id: Shew_3808
symbol: Shew_3808
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0043 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; Belongs to the peptidase S41A family.


ensembl_gene_id: Shew_3810
symbol: Shew_3810
gene_biotype: protein_coding
description:
  TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: she:Shewmr4_0041 transcriptional regulator, BadM/Rrf2 family.


ensembl_gene_id: Shew_3812
symbol: Shew_3812
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3916 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_3814
symbol: menB
gene_biotype: protein_coding
description:
  1,4-Dihydroxy-2-naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.


ensembl_gene_id: Shew_3818
symbol: Shew_3818
gene_biotype: protein_coding
description:
  TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sfr:Sfri_0212 copper-translocating P-type ATPase.


ensembl_gene_id: Shew_3822
symbol: Shew_3822
gene_biotype: protein_coding
description:
  PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2522 AAA ATPase, central domain protein; Belongs to the AAA ATPase family.


ensembl_gene_id: Shew_3824
symbol: Shew_3824
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: ilo:IL2609 transposon Tn7 transposition transposition regulatory protein TnsE.


ensembl_gene_id: Shew_3839
symbol: glmS
gene_biotype: protein_coding
description:
  Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: Shew_3840
symbol: Shew_3840
gene_biotype: protein_coding
description:
  Transcriptional regulator, DeoR family; PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: shm:Shewmr7_4013 transcriptional regulator, DeoR family.


ensembl_gene_id: Shew_3841
symbol: Shew_3841
gene_biotype: protein_coding
description:
  TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3922 TonB-dependent siderophore receptor.


ensembl_gene_id: Shew_3842
symbol: glmU
gene_biotype: protein_coding
description:
  Glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the t [...]


ensembl_gene_id: Shew_3843
symbol: Shew_3843
gene_biotype: protein_coding
description:
  PFAM: DsrE family protein; KEGG: ppr:PBPRB1553 putative uncharacterized protein involved in oxidation of intracellular sulfur.


ensembl_gene_id: Shew_3844
symbol: atpC
gene_biotype: protein_coding
description:
  ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: Shew_3845
symbol: atpD
gene_biotype: protein_coding
description:
  ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: Shew_3846
symbol: atpG
gene_biotype: protein_coding
description:
  ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: Shew_3847
symbol: atpA
gene_biotype: protein_coding
description:
  ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.


ensembl_gene_id: Shew_3848
symbol: atpH
gene_biotype: protein_coding
description:
  ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.


ensembl_gene_id: Shew_3849
symbol: atpF
gene_biotype: protein_coding
description:
  ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: Shew_3850
symbol: atpE
gene_biotype: protein_coding
description:
  ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: Shew_3851
symbol: atpB
gene_biotype: protein_coding
description:
  ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.


ensembl_gene_id: Shew_3853
symbol: Shew_3853
gene_biotype: protein_coding
description:
  Chromosome segregation DNA-binding protein; TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: shm:Shewmr7_4025 ParB-like partition proteins; Belongs to the ParB family.


ensembl_gene_id: Shew_3854
symbol: Shew_3854
gene_biotype: protein_coding
description:
  Chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO4756 ParA family protein.


ensembl_gene_id: Shew_3855
symbol: rsmG
gene_biotype: protein_coding
description:
  Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: Shew_3856
symbol: mnmG
gene_biotype: protein_coding
description:
  Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: Shew_3859
symbol: Shew_3859
gene_biotype: protein_coding
description:
  PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: ppr:PBPRB1417 hypothetical inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family.


ensembl_gene_id: Shew_3862
symbol: Shew_3862
gene_biotype: protein_coding
description:
  PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: rha:RHA1_ro03159 resolvase.


ensembl_gene_id: Shew_3865
symbol: mnmE
gene_biotype: protein_coding
description:
  tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: Shew_3866
symbol: yidC
gene_biotype: protein_coding
description:
  Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: Shew_3867
symbol: Shew_3867
gene_biotype: protein_coding
description:
  Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.


ensembl_gene_id: Shew_3868
symbol: rnpA
gene_biotype: protein_coding
description:
  Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: Shew_3869
symbol: rpmH
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L34; KEGG: shm:Shewmr7_4035 ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.


