# geneInfo

ensembl_gene_id: Shew_0001
symbol: dnaA
gene_biotype: protein_coding
description:
  Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.


ensembl_gene_id: Shew_0002
symbol: Shew_0002
gene_biotype: protein_coding
description:
  DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]


ensembl_gene_id: Shew_0003
symbol: recF
gene_biotype: protein_coding
description:
  DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.


ensembl_gene_id: Shew_0004
symbol: gyrB
gene_biotype: protein_coding
description:
  DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: Shew_0006
symbol: Shew_0006
gene_biotype: protein_coding
description:
  LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: Shew_0007
symbol: Shew_0007
gene_biotype: protein_coding
description:
  TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2.


ensembl_gene_id: Shew_0010
symbol: glyQ
gene_biotype: protein_coding
description:
  Glycine--tRNA ligase; PFAM: glycyl-tRNA synthetase, alpha subunit; KEGG: shm:Shewmr7_0009 glycyl-tRNA synthetase, alpha subunit.


ensembl_gene_id: Shew_0011
symbol: Shew_0011
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_0010 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase.


ensembl_gene_id: Shew_0015
symbol: tusA
gene_biotype: protein_coding
description:
  SirA family protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: Shew_0016
symbol: Shew_0016
gene_biotype: protein_coding
description:
  TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: vfi:VF1792 regulatory protein.


ensembl_gene_id: Shew_0018
symbol: fadA
gene_biotype: protein_coding
description:
  3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: Shew_0019
symbol: fadB
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.


ensembl_gene_id: Shew_0021
symbol: Shew_0021
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0029; KEGG: she:Shewmr4_0020 protein of unknown function UPF0029.


ensembl_gene_id: Shew_0022
symbol: Shew_0022
gene_biotype: protein_coding
description:
  Potassium uptake protein, TrkH family; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: Shew_0028
symbol: Shew_0028
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pen:PSEEN2735 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0031
symbol: Shew_0031
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3837 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_0032
symbol: Shew_0032
gene_biotype: protein_coding
description:
  TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3929 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family.


ensembl_gene_id: Shew_0034
symbol: Shew_0034
gene_biotype: protein_coding
description:
  PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0139 methyltransferase type 11.


ensembl_gene_id: Shew_0036
symbol: Shew_0036
gene_biotype: protein_coding
description:
  PFAM: phosphoesterase, PA-phosphatase related; KEGG: sde:Sde_1770 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family-like.


ensembl_gene_id: Shew_0038
symbol: Shew_0038
gene_biotype: protein_coding
description:
  PFAM: Excinuclease ABC, C subunit domain protein; KEGG: she:Shewmr4_0137 excinuclease ABC, C subunit domain protein.


ensembl_gene_id: Shew_0039
symbol: Shew_0039
gene_biotype: protein_coding
description:
  Oligopeptidase B; PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: son:SO0144 protease II.


ensembl_gene_id: Shew_0040
symbol: ribB
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: Shew_0041
symbol: Shew_0041
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0134 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; Nitrate and nitrite sensing domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_0044
symbol: Shew_0044
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: sdn:Sden_3430 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_0045
symbol: Shew_0045
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sdn:Sden_3429 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_0046
symbol: Shew_0046
gene_biotype: protein_coding
description:
  Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: Shew_0047
symbol: Shew_0047
gene_biotype: protein_coding
description:
  [molybdopterin synthase] sulfurylase; TIGRFAM: molybdopterin synthase sulfurylase MoeB; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: shm:Shewmr7_0125 molybdopterin synthase sulfurylase MoeB.


ensembl_gene_id: Shew_0048
symbol: Shew_0048
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdn:Sden_0827 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_0049
symbol: Shew_0049
gene_biotype: protein_coding
description:
  TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: vpa:VP1905 transporter, BCCT family; Belongs to the BCCT transporter (TC 2.A.15) family.


ensembl_gene_id: Shew_0050
symbol: Shew_0050
gene_biotype: protein_coding
description:
  PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: ppr:PBPRA2517 putative DNA polymerase III, epsilon subunit.


ensembl_gene_id: Shew_0051
symbol: Shew_0051
gene_biotype: protein_coding
description:
  PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: vpa:VP1902 CBS domain-containing protein.


ensembl_gene_id: Shew_0052
symbol: Shew_0052
gene_biotype: protein_coding
description:
  TIGRFAM: DNA binding domain, excisionase family; KEGG: she:Shewmr4_3713 DNA binding domain, excisionase family.


ensembl_gene_id: Shew_0053
symbol: fdhD
gene_biotype: protein_coding
description:
  Formate dehydrogenase, subunit FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: Shew_0056
symbol: Shew_0056
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4506 iron-sulfur cluster-binding protein.


ensembl_gene_id: Shew_0057
symbol: Shew_0057
gene_biotype: protein_coding
description:
  PFAM: cytoplasmic chaperone TorD family protein; KEGG: son:SO4507 TorA specific chaperone, putative.


ensembl_gene_id: Shew_0059
symbol: Shew_0059
gene_biotype: protein_coding
description:
  Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sfr:Sfri_0057 twin-arginine translocation pathway signal; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Shew_0060
symbol: Shew_0060
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3792 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_0061
symbol: Shew_0061
gene_biotype: protein_coding
description:
  TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: son:SO4511 formate dehydrogenase, C subunit, putative.


ensembl_gene_id: Shew_0063
symbol: Shew_0063
gene_biotype: protein_coding
description:
  Formate dehydrogenase alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3795 twin-arginine translocation pathway signal; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Shew_0064
symbol: Shew_0064
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3725 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_0065
symbol: Shew_0065
gene_biotype: protein_coding
description:
  TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shm:Shewmr7_3797 formate dehydrogenase, gamma subunit.


ensembl_gene_id: Shew_0070
symbol: Shew_0070
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; KEGG: sfr:Sfri_0073 iron-containing alcohol dehydrogenase.


ensembl_gene_id: Shew_0071
symbol: Shew_0071
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: sfr:Sfri_0074 transcriptional regulator, AraC family protein.


ensembl_gene_id: Shew_0073
symbol: Shew_0073
gene_biotype: protein_coding
description:
  PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: son:SO4520 coproporphyrinogen III oxidase.


ensembl_gene_id: Shew_0076
symbol: Shew_0076
gene_biotype: protein_coding
description:
  PFAM: Antibiotic biosynthesis monooxygenase; KEGG: nar:Saro_1420 antibiotic biosynthesis monooxygenase.


ensembl_gene_id: Shew_0079
symbol: Shew_0079
gene_biotype: protein_coding
description:
  TAP domain protein; PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: cps:CPS_0147 hydrolase, alpha/beta fold family.


ensembl_gene_id: Shew_0080
symbol: Shew_0080
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: vpa:VPA1277 sensor histidine kinase.


ensembl_gene_id: Shew_0081
symbol: Shew_0081
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hch:HCH_04118 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: Shew_0083
symbol: Shew_0083
gene_biotype: protein_coding
description:
  PFAM: 3-alpha; MOSC domain containing protein; KEGG: she:Shewmr4_0269 MOSC domain containing protein.


ensembl_gene_id: Shew_0085
symbol: Shew_0085
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3750 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_0086
symbol: Shew_0086
gene_biotype: protein_coding
description:
  Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone.


ensembl_gene_id: Shew_0087
symbol: moaA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: Shew_0088
symbol: Shew_0088
gene_biotype: protein_coding
description:
  Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: Shew_0089
symbol: moaC
gene_biotype: protein_coding
description:
  GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: Shew_0090
symbol: Shew_0090
gene_biotype: protein_coding
description:
  TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: shm:Shewmr7_3746 molybdopterin converting factor, subunit 1.


ensembl_gene_id: Shew_0092
symbol: Shew_0092
gene_biotype: protein_coding
description:
  TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: shm:Shewmr7_3744 molybdenum ABC transporter, periplasmic molybdate-binding protein.


ensembl_gene_id: Shew_0093
symbol: Shew_0093
gene_biotype: protein_coding
description:
  Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: Shew_0094
symbol: Shew_0094
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3742 ABC transporter-related protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Shew_0095
symbol: Shew_0095
gene_biotype: protein_coding
description:
  Conserved hypothetical protein 156; PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; conserved hypothetical protein 156; KEGG: vpa:VPA0694 hypothetical protein.


ensembl_gene_id: Shew_0097
symbol: Shew_0097
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3740 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_0098
symbol: Shew_0098
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4427 sensor histidine kinase.


ensembl_gene_id: Shew_0099
symbol: Shew_0099
gene_biotype: protein_coding
description:
  TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: she:Shewmr4_0283 pseudouridine synthase Rlu family protein, TIGR01621.


ensembl_gene_id: Shew_0100
symbol: Shew_0100
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0057; KEGG: shm:Shewmr7_3736 protein of unknown function UPF0057.


ensembl_gene_id: Shew_0103
symbol: gltS
gene_biotype: protein_coding
description:
  Sodium/glutamate symporter; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: Shew_0104
symbol: Shew_0104
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF333; KEGG: shm:Shewmr7_0123 protein of unknown function DUF333.


ensembl_gene_id: Shew_0106
symbol: nfuA
gene_biotype: protein_coding
description:
  HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: Shew_0107
symbol: Shew_0107
gene_biotype: protein_coding
description:
  TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO4617 DNA-damage-inducible protein F.


ensembl_gene_id: Shew_0109
symbol: cheB
gene_biotype: protein_coding
description:
  Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: Shew_0110
symbol: Shew_0110
gene_biotype: protein_coding
description:
  MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: Shew_0111
symbol: Shew_0111
gene_biotype: protein_coding
description:
  PFAM: chemotaxis sensory transducer; PAS fold-4 domain protein; SMART: PAS domain containing protein; KEGG: cvi:CV3438 probable methyl-accepting chemotaxis protein.


ensembl_gene_id: Shew_0113
symbol: Shew_0113
gene_biotype: protein_coding
description:
  CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: tcx:Tcr_1612 CheA signal transduction histidine kinase.


ensembl_gene_id: Shew_0117
symbol: cyoE1
gene_biotype: protein_coding
description:
  Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: Shew_0123
symbol: Shew_0123
gene_biotype: protein_coding
description:
  PFAM: cytochrome c oxidase assembly protein CtaG/Cox11; KEGG: shm:Shewmr7_3866 cytochrome c oxidase assembly protein CtaG/Cox11.


ensembl_gene_id: Shew_0124
symbol: Shew_0124
gene_biotype: protein_coding
description:
  Cytochrome-c oxidase; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.


ensembl_gene_id: Shew_0125
symbol: Shew_0125
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).


ensembl_gene_id: Shew_0126
symbol: Shew_0126
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: Shew_0127
symbol: lexA
gene_biotype: protein_coding
description:
  SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: Shew_0128
symbol: Shew_0128
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0162 HAD-superfamily hydrolase, subfamily IA, variant 3.


ensembl_gene_id: Shew_0130
symbol: cysQ
gene_biotype: protein_coding
description:
  3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: Shew_0133
symbol: Shew_0133
gene_biotype: protein_coding
description:
  PFAM: phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1; KEGG: son:SO0194 acyltransferase family protein.


ensembl_gene_id: Shew_0134
symbol: selU
gene_biotype: protein_coding
description:
  tRNA 2-selenouridine synthase; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.


ensembl_gene_id: Shew_0136
symbol: Shew_0136
gene_biotype: protein_coding
description:
  Delta-9 acyl-phospholipid desaturase; PFAM: fatty acid desaturase; KEGG: she:Shewmr4_0176 stearoyl-CoA 9-desaturase.


ensembl_gene_id: Shew_0138
symbol: trmA
gene_biotype: protein_coding
description:
  tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: Shew_0142
symbol: birA
gene_biotype: protein_coding
description:
  biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: Shew_0143
symbol: coaA
gene_biotype: protein_coding
description:
  TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: shm:Shewmr7_0178 pantothenate kinase.


ensembl_gene_id: Shew_0144
symbol: tuf1
gene_biotype: protein_coding
description:
  Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.


ensembl_gene_id: Shew_0145
symbol: secE
gene_biotype: protein_coding
description:
  Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: Shew_0146
symbol: nusG
gene_biotype: protein_coding
description:
  Transcription antitermination protein nusG; Participates in transcription elongation, termination and antitermination.


ensembl_gene_id: Shew_0147
symbol: rplK
gene_biotype: protein_coding
description:
  LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: Shew_0148
symbol: rplA
gene_biotype: protein_coding
description:
  LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: Shew_0149
symbol: rplJ
gene_biotype: protein_coding
description:
  LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: Shew_0150
symbol: rplL
gene_biotype: protein_coding
description:
  LSU ribosomal protein L12P / LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: Shew_0151
symbol: rpoB
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Shew_0152
symbol: rpoC
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Shew_0154
symbol: rpsG
gene_biotype: protein_coding
description:
  SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: Shew_0155
symbol: fusA
gene_biotype: protein_coding
description:
  Translation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...]


ensembl_gene_id: Shew_0157
symbol: rpsJ
gene_biotype: protein_coding
description:
  SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: Shew_0158
symbol: rplC
gene_biotype: protein_coding
description:
  LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: Shew_0159
symbol: rplD
gene_biotype: protein_coding
description:
  LSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.


ensembl_gene_id: Shew_0160
symbol: rplW
gene_biotype: protein_coding
description:
  LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: Shew_0161
symbol: rplB
gene_biotype: protein_coding
description:
  LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: Shew_0162
symbol: rpsS
gene_biotype: protein_coding
description:
  SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: Shew_0163
symbol: rplV
gene_biotype: protein_coding
description:
  LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).


ensembl_gene_id: Shew_0164
symbol: rpsC
gene_biotype: protein_coding
description:
  SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: Shew_0165
symbol: rplP
gene_biotype: protein_coding
description:
  LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: Shew_0166
symbol: rpmC
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L29; KEGG: shm:Shewmr7_0202 ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.


ensembl_gene_id: Shew_0167
symbol: rpsQ
gene_biotype: protein_coding
description:
  SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: Shew_0168
symbol: rplN
gene_biotype: protein_coding
description:
  LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: Shew_0169
symbol: rplX
gene_biotype: protein_coding
description:
  LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: Shew_0170
symbol: rplE
gene_biotype: protein_coding
description:
  LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: Shew_0171
symbol: rpsN
gene_biotype: protein_coding
description:
  SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: Shew_0172
symbol: rpsH
gene_biotype: protein_coding
description:
  SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: Shew_0173
symbol: rplF
gene_biotype: protein_coding
description:
  LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: Shew_0174
symbol: rplR
gene_biotype: protein_coding
description:
  LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: Shew_0175
symbol: rpsE
gene_biotype: protein_coding
description:
  SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: Shew_0177
symbol: rplO
gene_biotype: protein_coding
description:
  LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.


ensembl_gene_id: Shew_0178
symbol: secY
gene_biotype: protein_coding
description:
  Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: Shew_0179
symbol: rpmJ
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L36; KEGG: shm:Shewmr7_0215 ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.


ensembl_gene_id: Shew_0180
symbol: rpsM
gene_biotype: protein_coding
description:
  SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: Shew_0181
symbol: rpsK
gene_biotype: protein_coding
description:
  SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.


ensembl_gene_id: Shew_0182
symbol: rpsD
gene_biotype: protein_coding
description:
  SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: Shew_0183
symbol: rpoA
gene_biotype: protein_coding
description:
  DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: Shew_0186
symbol: ccmE
gene_biotype: protein_coding
description:
  CcmE/CycJ protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: Shew_0187
symbol: Shew_0187
gene_biotype: protein_coding
description:
  Heme exporter protein D (CcmD); Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: Shew_0188
symbol: ccmC
gene_biotype: protein_coding
description:
  Heme exporter protein CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: Shew_0189
symbol: Shew_0189
gene_biotype: protein_coding
description:
  Heme exporter protein CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: Shew_0190
symbol: ccmA
gene_biotype: protein_coding
description:
  Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: Shew_0192
symbol: Shew_0192
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_0228 TPR repeat-containing protein.


ensembl_gene_id: Shew_0193
symbol: Shew_0193
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_0229 cytochrome c-type biogenesis protein CcmF.


ensembl_gene_id: Shew_0194
symbol: Shew_0194
gene_biotype: protein_coding
description:
  TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_0230 periplasmic protein thiol--disulphide oxidoreductase DsbE.


ensembl_gene_id: Shew_0198
symbol: Shew_0198
gene_biotype: protein_coding
description:
  TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: shm:Shewmr7_0233 competence/damage-inducible protein CinA; Belongs to the CinA family.


ensembl_gene_id: Shew_0200
symbol: ppc
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.


ensembl_gene_id: Shew_0201
symbol: Shew_0201
gene_biotype: protein_coding
description:
  TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sfr:Sfri_0190 acetylornithine deacetylase (ArgE).


ensembl_gene_id: Shew_0202
symbol: argC
gene_biotype: protein_coding
description:
  N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: Shew_0203
symbol: argB
gene_biotype: protein_coding
description:
  N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.


ensembl_gene_id: Shew_0204
symbol: Shew_0204
gene_biotype: protein_coding
description:
  Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: Shew_0205
symbol: argG
gene_biotype: protein_coding
description:
  PFAM: argininosuccinate synthase; KEGG: shm:Shewmr7_0239 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.


ensembl_gene_id: Shew_0206
symbol: argH
gene_biotype: protein_coding
description:
  TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: sdn:Sden_0254 argininosuccinate lyase.


ensembl_gene_id: Shew_0207
symbol: Shew_0207
gene_biotype: protein_coding
description:
  TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: sfr:Sfri_0369 penicillin-binding protein, 1A family protein.


ensembl_gene_id: Shew_0208
symbol: Shew_0208
gene_biotype: protein_coding
description:
  TIGRFAM: type IV pilus assembly protein PilM; KEGG: shm:Shewmr7_0242 type IV pilus assembly protein PilM.


ensembl_gene_id: Shew_0212
symbol: Shew_0212
gene_biotype: protein_coding
description:
  TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3699 type IV pilus secretin PilQ.


ensembl_gene_id: Shew_0213
symbol: aroK
gene_biotype: protein_coding
description:
  Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: Shew_0214
symbol: aroB
gene_biotype: protein_coding
description:
  3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.


ensembl_gene_id: Shew_0216
symbol: Shew_0216
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_0264 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.


ensembl_gene_id: Shew_0219
symbol: Shew_0219
gene_biotype: protein_coding
description:
  PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: son:SO0292 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.


ensembl_gene_id: Shew_0220
symbol: gph
gene_biotype: protein_coding
description:
  Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: Shew_0221
symbol: trpS
gene_biotype: protein_coding
description:
  tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: Shew_0222
symbol: Shew_0222
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0295 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0223
symbol: Shew_0223
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6, transmembrane; KEGG: she:Shewmr4_3688 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Shew_0224
symbol: Shew_0224
gene_biotype: protein_coding
description:
  PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shm:Shewmr7_0258 transport-associated.


ensembl_gene_id: Shew_0225
symbol: gmhA
gene_biotype: protein_coding
description:
  Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: Shew_0226
symbol: Shew_0226
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0102; KEGG: she:Shewmr4_3685 protein of unknown function UPF0102; Belongs to the UPF0102 family.


ensembl_gene_id: Shew_0228
symbol: rsmI
gene_biotype: protein_coding
description:
  Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: Shew_0229
symbol: Shew_0229
gene_biotype: protein_coding
description:
  SMART: extracellular solute-binding protein, family 3; KEGG: hch:HCH_06608 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain.


ensembl_gene_id: Shew_0233
symbol: Shew_0233
gene_biotype: protein_coding
description:
  PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: she:Shewmr4_3670 radical SAM N-terminal domain protein.


ensembl_gene_id: Shew_0234
symbol: Shew_0234
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1232; KEGG: she:Shewmr4_3655 protein of unknown function DUF1232.


ensembl_gene_id: Shew_0236
symbol: Shew_0236
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_0770 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0237
symbol: Shew_0237
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: cps:CPS_3839 methyl-accepting chemotaxis protein.


ensembl_gene_id: Shew_0239
symbol: Shew_0239
gene_biotype: protein_coding
description:
  TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shm:Shewmr7_0283 formate dehydrogenase, gamma subunit.


ensembl_gene_id: Shew_0240
symbol: Shew_0240
gene_biotype: protein_coding
description:
  PFAM: cytoplasmic chaperone TorD family protein; KEGG: shm:Shewmr7_0284 cytoplasmic chaperone TorD family protein.


ensembl_gene_id: Shew_0241
symbol: Shew_0241
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_0285 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_0242
symbol: Shew_0242
gene_biotype: protein_coding
description:
  PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: shm:Shewmr7_0286 twin-arginine translocation pathway signal; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Shew_0244
symbol: Shew_0244
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: vvy:VV2222 tetrathionate reductase, subunit B.


ensembl_gene_id: Shew_0245
symbol: Shew_0245
gene_biotype: protein_coding
description:
  PFAM: molydopterin dinucleotide-binding region; KEGG: ppr:PBPRB1372 hypothetical tetrathionate reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Shew_0248
symbol: Shew_0248
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; KEGG: psp:PSPPH_3302 ribosomal protein alanine acetyltransferase.


ensembl_gene_id: Shew_0250
symbol: Shew_0250
gene_biotype: protein_coding
description:
  Transcriptional regulator, MerR family; PFAM: regulatory protein, MerR; Methyltransferase type 11; Methyltransferase type 12; KEGG: vvy:VV0135 putative transcriptional regulator.


ensembl_gene_id: Shew_0255
symbol: Shew_0255
gene_biotype: protein_coding
description:
  PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: vvy:VV0139 hypothetical protein.


ensembl_gene_id: Shew_0257
symbol: Shew_0257
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: sdn:Sden_0280 peptidase S9, prolyl oligopeptidase active site region.


ensembl_gene_id: Shew_0262
symbol: selO
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).


ensembl_gene_id: Shew_0264
symbol: srkA
gene_biotype: protein_coding
description:
  Aminoglycoside phosphotransferase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: Shew_0267
symbol: zapB
gene_biotype: protein_coding
description:
  Protein of unknown function DUF904; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: Shew_0268
symbol: Shew_0268
gene_biotype: protein_coding
description:
  Transcriptional antiterminator, Rof; PFAM: Modulator of Rho-dependent transcription termination; KEGG: shm:Shewmr7_0308 transcriptional antiterminator, Rof.


ensembl_gene_id: Shew_0269
symbol: Shew_0269
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1223; KEGG: shm:Shewmr7_0309 protein of unknown function DUF1223.


ensembl_gene_id: Shew_0276
symbol: Shew_0276
gene_biotype: protein_coding
description:
  TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0299 flavocytochrome c; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Shew_0278
symbol: Shew_0278
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_0310 branched-chain amino acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase, class IV.


ensembl_gene_id: Shew_0280
symbol: Shew_0280
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_0316 transcriptional regulator, GntR family.


ensembl_gene_id: Shew_0281
symbol: Shew_0281
gene_biotype: protein_coding
description:
  PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase.


ensembl_gene_id: Shew_0282
symbol: Shew_0282
gene_biotype: protein_coding
description:
  PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_0319 phospholipid/glycerol acyltransferase.


ensembl_gene_id: Shew_0283
symbol: Shew_0283
gene_biotype: protein_coding
description:
  Mg chelatase, subunit ChlI; KEGG: son:SO0349 magnesium chelatase family protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.


ensembl_gene_id: Shew_0284
symbol: Shew_0284
gene_biotype: protein_coding
description:
  PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: son:SO4351 CBS domain protein.


ensembl_gene_id: Shew_0285
symbol: Shew_0285
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdn:Sden_0972 GGDEF domain.


ensembl_gene_id: Shew_0286
symbol: Shew_0286
gene_biotype: protein_coding
description:
  SMART: extracellular solute-binding protein, family 3; KEGG: she:Shewmr4_0358 ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein.


ensembl_gene_id: Shew_0287
symbol: Shew_0287
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0360 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0288
symbol: Shew_0288
gene_biotype: protein_coding
description:
  Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: Shew_0289
symbol: Shew_0289
gene_biotype: protein_coding
description:
  TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: she:Shewmr4_0362 acetolactate synthase, large subunit, biosynthetic type.


ensembl_gene_id: Shew_0291
symbol: ilvE
gene_biotype: protein_coding
description:
  Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Shew_0292
symbol: ilvD
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3662 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.


ensembl_gene_id: Shew_0293
symbol: ilvA
gene_biotype: protein_coding
description:
  L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: Shew_0296
symbol: Shew_0296
gene_biotype: protein_coding
description:
  PFAM: heat shock protein Hsp20; KEGG: bja:blr7961 probable HspC2 heat shock protein; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Shew_0302
symbol: Shew_0302
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase; PFAM: phosphoesterase, PA-phosphatase related; KEGG: shm:Shewmr7_3657 phosphoesterase, PA-phosphatase related.


ensembl_gene_id: Shew_0303
symbol: Shew_0303
gene_biotype: protein_coding
description:
  PFAM: Inner membrane CreD family protein; KEGG: shm:Shewmr7_3656 inner membrane CreD family protein.


ensembl_gene_id: Shew_0304
symbol: Shew_0304
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF526; KEGG: shm:Shewmr7_3651 protein of unknown function DUF526.


ensembl_gene_id: Shew_0305
symbol: rep
gene_biotype: protein_coding
description:
  ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: Shew_0306
symbol: Shew_0306
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: she:Shewmr4_0377 diguanylate cyclase/phosphodiesterase with GAF sensor.


ensembl_gene_id: Shew_0307
symbol: Shew_0307
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO4323 GGDEF domain protein.


ensembl_gene_id: Shew_0310
symbol: Shew_0310
gene_biotype: protein_coding
description:
  TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: sdn:Sden_0381 type I secretion outer membrane protein, TolC.


ensembl_gene_id: Shew_0311
symbol: Shew_0311
gene_biotype: protein_coding
description:
  TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3644 type I secretion membrane fusion protein, HlyD family.


ensembl_gene_id: Shew_0312
symbol: Shew_0312
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4318 toxin secretion ATP-binding protein.


ensembl_gene_id: Shew_0313
symbol: Shew_0313
gene_biotype: protein_coding
description:
  TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; von Willebrand factor, type A; KEGG: shm:Shewmr7_3642 putative outer membrane adhesin like protein.


ensembl_gene_id: Shew_0314
symbol: Shew_0314
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_0384 hypothetical protein; TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; SMART: Cadherin.


ensembl_gene_id: Shew_0316
symbol: Shew_0316
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF513, hemX; KEGG: she:Shewmr4_0386 protein of unknown function DUF513, HemX.


ensembl_gene_id: Shew_0317
symbol: Shew_0317
gene_biotype: protein_coding
description:
  Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: Shew_0318
symbol: hemC
gene_biotype: protein_coding
description:
  Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: Shew_0319
symbol: Shew_0319
gene_biotype: protein_coding
description:
  PFAM: adenylate cyclase, class-I; KEGG: shm:Shewmr7_3637 adenylate cyclase; Belongs to the adenylyl cyclase class-1 family.


ensembl_gene_id: Shew_0320
symbol: cyaY
gene_biotype: protein_coding
description:
  Frataxin family protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: Shew_0322
symbol: lysA
gene_biotype: protein_coding
description:
  Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: Shew_0323
symbol: dapF
gene_biotype: protein_coding
description:
  Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: Shew_0325
symbol: xerC
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: Shew_0326
symbol: Shew_0326
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_3630 HAD-superfamily hydrolase, subfamily IA, variant 1.


ensembl_gene_id: Shew_0328
symbol: Shew_0328
gene_biotype: protein_coding
description:
  Protein of unknown function DUF542, ScdA domain protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters; Belongs to the RIC family.


ensembl_gene_id: Shew_0329
symbol: fis
gene_biotype: protein_coding
description:
  Transcriptional regulator, Fis family; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: Shew_0330
symbol: dusB
gene_biotype: protein_coding
description:
  Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: Shew_0331
symbol: prmA
gene_biotype: protein_coding
description:
  LSU ribosomal protein L11P methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: Shew_0332
symbol: Shew_0332
gene_biotype: protein_coding
description:
  PFAM: fumarate reductase respiratory complex, transmembrane subunit; KEGG: shm:Shewmr7_3623 fumarate reductase respiratory complex, transmembrane subunit.


ensembl_gene_id: Shew_0333
symbol: Shew_0333
gene_biotype: protein_coding
description:
  PFAM: fumarate reductase respiratory complex, transmembrane subunit; KEGG: she:Shewmr4_0403 fumarate reductase respiratory complex, transmembrane subunit.


ensembl_gene_id: Shew_0334
symbol: Shew_0334
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3621 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein.


ensembl_gene_id: Shew_0335
symbol: Shew_0335
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_3620 succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: Shew_0336
symbol: Shew_0336
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0402 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0337
symbol: rho
gene_biotype: protein_coding
description:
  Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: Shew_0338
symbol: Shew_0338
gene_biotype: protein_coding
description:
  TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: shm:Shewmr7_3615 thioredoxin; Belongs to the thioredoxin family.


ensembl_gene_id: Shew_0339
symbol: rhlB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: Shew_0341
symbol: Shew_0341
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sdn:Sden_2404 TonB-dependent receptor.


ensembl_gene_id: Shew_0347
symbol: Shew_0347
gene_biotype: protein_coding
description:
  PFAM: cytochrome c assembly protein; KEGG: she:Shewmr4_0487 cytochrome c-type biogenesis protein CcmF.


ensembl_gene_id: Shew_0348
symbol: Shew_0348
gene_biotype: protein_coding
description:
  Cytochrome c, putative; Respiratory sulfite reductase that catalyzes the reduction of sulfite to sulfide in a single step, consuming six electrons in the process; Belongs to the multiheme cytochrome c family.


ensembl_gene_id: Shew_0350
symbol: Shew_0350
gene_biotype: protein_coding
description:
  Peptidylprolyl isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_0490 FKBP-type peptidyl-prolyl isomerase domain protein.


ensembl_gene_id: Shew_0351
symbol: Shew_0351
gene_biotype: protein_coding
description:
  PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO0482 formate-dependent nitrite reductase, NrfG protein.


ensembl_gene_id: Shew_0352
symbol: Shew_0352
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_0492 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_0355
symbol: Shew_0355
gene_biotype: protein_coding
description:
  PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: shm:Shewmr7_3535 periplasmic copper-binding protein.


ensembl_gene_id: Shew_0356
symbol: Shew_0356
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_0496 ABC transporter-related protein.


ensembl_gene_id: Shew_0358
symbol: Shew_0358
gene_biotype: protein_coding
description:
  PFAM: transcriptional regulator domain protein; KEGG: shm:Shewmr7_3532 transcriptional regulator, CadC.


ensembl_gene_id: Shew_0359
symbol: Shew_0359
gene_biotype: protein_coding
description:
  PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: she:Shewmr4_0505 oxidoreductase FAD/NAD(P)-binding domain protein.


ensembl_gene_id: Shew_0360
symbol: ubiD
gene_biotype: protein_coding
description:
  3-octaprenyl-4hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: Shew_0362
symbol: Shew_0362
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1481 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Belongs to the peptidase S26 family.


ensembl_gene_id: Shew_0363
symbol: Shew_0363
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yps:YPTB2218 haloacid dehalogenase-like hydrolase family protein.


ensembl_gene_id: Shew_0366
symbol: Shew_0366
gene_biotype: protein_coding
description:
  TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; COX aromatic rich domain protein; KEGG: she:Shewmr4_3823 ubiquinol oxidase, subunit II.


ensembl_gene_id: Shew_0367
symbol: Shew_0367
gene_biotype: protein_coding
description:
  PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_3915 cytochrome-c oxidase; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: Shew_0371
symbol: Shew_0371
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; transcription activator, effector binding; KEGG: stt:t3096 possible AraC-family transcriptional regulator.


ensembl_gene_id: Shew_0373
symbol: Shew_0373
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF971; KEGG: she:Shewmr4_3523 protein of unknown function DUF971.


ensembl_gene_id: Shew_0374
symbol: hslU
gene_biotype: protein_coding
description:
  Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: Shew_0375
symbol: hslV
gene_biotype: protein_coding
description:
  HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: Shew_0379
symbol: priA
gene_biotype: protein_coding
description:
  Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: Shew_0383
symbol: Shew_0383
gene_biotype: protein_coding
description:
  PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: sfr:Sfri_3757 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).


ensembl_gene_id: Shew_0384
symbol: Shew_0384
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_0461 diguanylate cyclase/phosphodiesterase.


ensembl_gene_id: Shew_0389
symbol: Shew_0389
gene_biotype: protein_coding
description:
  TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3486 pilus (MSHA type) biogenesis protein MshL.


ensembl_gene_id: Shew_0391
symbol: Shew_0391
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_0468 tetratricopeptide TPR_2 repeat protein.


ensembl_gene_id: Shew_0392
symbol: Shew_0392
gene_biotype: protein_coding
description:
  PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: shm:Shewmr7_0469 type II secretion system protein E.


ensembl_gene_id: Shew_0403
symbol: Shew_0403
gene_biotype: protein_coding
description:
  TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; KEGG: shm:Shewmr7_0479 cell shape determining protein, MreB/Mrl family.


ensembl_gene_id: Shew_0405
symbol: Shew_0405
gene_biotype: protein_coding
description:
  Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: Shew_0406
symbol: Shew_0406
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: Shew_0407
symbol: Shew_0407
gene_biotype: protein_coding
description:
  TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: she:Shewmr4_3468 ribonuclease, Rne/Rng family.


ensembl_gene_id: Shew_0409
symbol: Shew_0409
gene_biotype: protein_coding
description:
  PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: son:SO4092 hydrolase, carbon-nitrogen family.


ensembl_gene_id: Shew_0410
symbol: Shew_0410
gene_biotype: protein_coding
description:
  PFAM: peptidase U62, modulator of DNA gyrase; KEGG: shm:Shewmr7_0486 peptidase U62, modulator of DNA gyrase.


ensembl_gene_id: Shew_0415
symbol: Shew_0415
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF615; KEGG: sdn:Sden_3068 protein of unknown function DUF615; Belongs to the UPF0307 family.


ensembl_gene_id: Shew_0416
symbol: Shew_0416
gene_biotype: protein_coding
description:
  PFAM: peptidase U62, modulator of DNA gyrase; KEGG: sfr:Sfri_3721 peptidase U62, modulator of DNA gyrase.


ensembl_gene_id: Shew_0418
symbol: Shew_0418
gene_biotype: protein_coding
description:
  TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: sde:Sde_3779 arsenical pump membrane protein, putative.


ensembl_gene_id: Shew_0419
symbol: Shew_0419
gene_biotype: protein_coding
description:
  KEGG: son:SO0538 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Shew_0424
symbol: Shew_0424
gene_biotype: protein_coding
description:
  TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdn:Sden_0649 amino acid carrier protein.


ensembl_gene_id: Shew_0426
symbol: Shew_0426
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sfr:Sfri_3538 ABC transporter-related protein.


ensembl_gene_id: Shew_0430
symbol: Shew_0430
gene_biotype: protein_coding
description:
  Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: Shew_0436
symbol: Shew_0436
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_3475 diguanylate cyclase/phosphodiesterase.


ensembl_gene_id: Shew_0439
symbol: cheD
gene_biotype: protein_coding
description:
  CheD, stimulates methylation of MCP proteins; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.


ensembl_gene_id: Shew_0440
symbol: cmoM
gene_biotype: protein_coding
description:
  Methyltransferase type 12; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: Shew_0443
symbol: fhs
gene_biotype: protein_coding
description:
  PFAM: formate-tetrahydrofolate ligase, FTHFS; KEGG: son:SO0560 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.


ensembl_gene_id: Shew_0448
symbol: Shew_0448
gene_biotype: protein_coding
description:
  PFAM: periplasmic solute binding protein; KEGG: shm:Shewmr7_3463 periplasmic solute binding protein; Belongs to the bacterial solute-binding protein 9 family.


ensembl_gene_id: Shew_0450
symbol: Shew_0450
gene_biotype: protein_coding
description:
  KEGG: son:SO0567 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


ensembl_gene_id: Shew_0451
symbol: rraB
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1260; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: Shew_0452
symbol: Shew_0452
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sfr:Sfri_3512 diguanylate cyclase.


ensembl_gene_id: Shew_0457
symbol: rapA
gene_biotype: protein_coding
description:
  SNF2-related protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: Shew_0458
symbol: Shew_0458
gene_biotype: protein_coding
description:
  PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein, PINc; KEGG: son:SO0576 PhoH family protein.


ensembl_gene_id: Shew_0459
symbol: Shew_0459
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0577 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_0466
symbol: Shew_0466
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_0550 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_0467
symbol: Shew_0467
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3401 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_0468
symbol: Shew_0468
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_1434 transcriptional regulator, LysR family protein.


ensembl_gene_id: Shew_0470
symbol: Shew_0470
gene_biotype: protein_coding
description:
  TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: she:Shewmr4_3399 MATE efflux family protein.


ensembl_gene_id: Shew_0471
symbol: groS
gene_biotype: protein_coding
description:
  Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: Shew_0472
symbol: groL
gene_biotype: protein_coding
description:
  Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: Shew_0478
symbol: Shew_0478
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_0557 transcriptional regulator, XRE family.


ensembl_gene_id: Shew_0485
symbol: Shew_0485
gene_biotype: protein_coding
description:
  PFAM: Cold-shock protein, DNA-binding; Excalibur domain protein; SMART: Cold shock protein; KEGG: sfr:Sfri_3647 cold-shock DNA-binding domain protein.


ensembl_gene_id: Shew_0490
symbol: Shew_0490
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: shm:Shewmr7_3813 peptidase S9, prolyl oligopeptidase active site domain protein.


ensembl_gene_id: Shew_0492
symbol: Shew_0492
gene_biotype: protein_coding
description:
  TIGRFAM: hemerythrin-like metal-binding protein; PFAM: chemotaxis sensory transducer; Hemerythrin HHE cation binding domain protein; KEGG: son:SO3890 methyl-accepting chemotaxis protein.


ensembl_gene_id: Shew_0496
symbol: Shew_0496
gene_biotype: protein_coding
description:
  TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: shm:Shewmr7_3308 amino acid carrier protein.


ensembl_gene_id: Shew_0497
symbol: Shew_0497
gene_biotype: protein_coding
description:
  PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: ppr:PBPRA2914 hypothetical sulfate permease family protein.


ensembl_gene_id: Shew_0501
symbol: Shew_0501
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF134; KEGG: son:SO0727 hypothetical protein; Belongs to the UPF0251 family.


ensembl_gene_id: Shew_0505
symbol: Shew_0505
gene_biotype: protein_coding
description:
  Nitrite reductase (cytochrome; PFAM: cytochrome c552; KEGG: sfr:Sfri_3036 nitrite reductase (cytochrome; ammonia-forming); Belongs to the cytochrome c-552 family.


ensembl_gene_id: Shew_0506
symbol: Shew_0506
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4154 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0507
symbol: Shew_0507
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: son:SO4153 N-ethylmaleimide reductase, putative.


ensembl_gene_id: Shew_0511
symbol: Shew_0511
gene_biotype: protein_coding
description:
  TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: son:SO4148 HlyD family secretion protein.


ensembl_gene_id: Shew_0512
symbol: Shew_0512
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4147 ABC transporter, ATP-binding/permease protein.


ensembl_gene_id: Shew_0513
symbol: Shew_0513
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; KEGG: son:SO4146 toxin secretion ABC transporter protein, HlyB family.


ensembl_gene_id: Shew_0519
symbol: Shew_0519
gene_biotype: protein_coding
description:
  Methionine repressor, MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.


ensembl_gene_id: Shew_0520
symbol: Shew_0520
gene_biotype: protein_coding
description:
  Cystathionine gamma-synthase; KEGG: she:Shewmr4_3439 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.


ensembl_gene_id: Shew_0521
symbol: Shew_0521
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_3438 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: Shew_0522
symbol: Shew_0522
gene_biotype: protein_coding
description:
  TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: shm:Shewmr7_0514 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.


ensembl_gene_id: Shew_0527
symbol: Shew_0527
gene_biotype: protein_coding
description:
  PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfr:Sfri_3249 Sel1 domain protein repeat-containing protein.


ensembl_gene_id: Shew_0531
symbol: deaD
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: Shew_0533
symbol: uvrA
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: Shew_0534
symbol: Shew_0534
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3420 major facilitator superfamily MFS_1.


ensembl_gene_id: Shew_0535
symbol: Shew_0535
gene_biotype: protein_coding
description:
  Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: Shew_0536
symbol: dusA
gene_biotype: protein_coding
description:
  TIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: Shew_0538
symbol: Shew_0538
gene_biotype: protein_coding
description:
  Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: she:Shewmr4_3241 phage shock protein C, PspC.


ensembl_gene_id: Shew_0541
symbol: Shew_0541
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF461; KEGG: shm:Shewmr7_0750 protein of unknown function DUF461.


ensembl_gene_id: Shew_0544
symbol: Shew_0544
gene_biotype: protein_coding
description:
  TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: son:SO3904 outer membrane protein TolC.


ensembl_gene_id: Shew_0545
symbol: Shew_0545
gene_biotype: protein_coding
description:
  ADP-ribose diphosphatase; PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_3235 nucleoside diphosphate pyrophosphatase.


ensembl_gene_id: Shew_0546
symbol: Shew_0546
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1249; KEGG: she:Shewmr4_3234 protein of unknown function DUF1249.


ensembl_gene_id: Shew_0547
symbol: cpdA
gene_biotype: protein_coding
description:
  Calcineurin phosphoesterase C-terminal domain protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: Shew_0548
symbol: Shew_0548
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0227; KEGG: she:Shewmr4_3232 protein of unknown function UPF0227.


ensembl_gene_id: Shew_0549
symbol: parE
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: Shew_0551
symbol: parC
gene_biotype: protein_coding
description:
  DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: Shew_0552
symbol: Shew_0552
gene_biotype: protein_coding
description:
  PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sdn:Sden_3217 BFD-like (2Fe-2S)-binding region.


ensembl_gene_id: Shew_0553
symbol: Shew_0553
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: she:Shewmr4_0584 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.


ensembl_gene_id: Shew_0554
symbol: Shew_0554
gene_biotype: protein_coding
description:
  PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: shm:Shewmr7_3444 glycerophosphoryl diester phosphodiesterase.


ensembl_gene_id: Shew_0556
symbol: Shew_0556
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_3442 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Shew_0557
symbol: psd
gene_biotype: protein_coding
description:
  Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: Shew_0558
symbol: rsgA
gene_biotype: protein_coding
description:
  Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: Shew_0559
symbol: orn
gene_biotype: protein_coding
description:
  Exonuclease, RNase T and DNA polymerase III; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: Shew_0561
symbol: nnrD
gene_biotype: protein_coding
description:
  Carbohydrate kinase, YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]


ensembl_gene_id: Shew_0562
symbol: Shew_0562
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0079; KEGG: she:Shewmr4_0594 protein of unknown function UPF0079.


ensembl_gene_id: Shew_0563
symbol: Shew_0563
gene_biotype: protein_coding
description:
  N-acetylmuramoyl-L-alanine amidase; PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: she:Shewmr4_0595 N-acetylmuramoyl-L-alanine amidase.


ensembl_gene_id: Shew_0564
symbol: mutL
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: Shew_0565
symbol: miaA
gene_biotype: protein_coding
description:
  tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: Shew_0566
symbol: hfq
gene_biotype: protein_coding
description:
  RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: Shew_0567
symbol: hflX
gene_biotype: protein_coding
description:
  GTP-binding protein, HSR1-related; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: Shew_0570
symbol: Shew_0570
gene_biotype: protein_coding
description:
  Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: Shew_0571
symbol: Shew_0571
gene_biotype: protein_coding
description:
  Cytochrome b/b6, N-terminal domain; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.


ensembl_gene_id: Shew_0573
symbol: Shew_0573
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: shm:Shewmr7_3425 glutathione S-transferase, N-terminal domain protein; Belongs to the GST superfamily.


ensembl_gene_id: Shew_0575
symbol: Shew_0575
gene_biotype: protein_coding
description:
  Aminodeoxychorismate synthase, glutamine amidotransferase subunit; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: son:SO0613 para-aminobenzoate synthase glutamine amidotransferase, component II.


ensembl_gene_id: Shew_0576
symbol: Shew_0576
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: she:Shewmr4_0608 peptidase S9, prolyl oligopeptidase active site domain protein.


ensembl_gene_id: Shew_0578
symbol: argD
gene_biotype: protein_coding
description:
  TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: son:SO0617 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: Shew_0580
symbol: astD
gene_biotype: protein_coding
description:
  Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: Shew_0582
symbol: Shew_0582
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO0621 sensor histidine kinase.


ensembl_gene_id: Shew_0583
symbol: Shew_0583
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3414 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_0585
symbol: Shew_0585
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: sfr:Sfri_3292 transcriptional regulator, Crp/Fnr family protein.


ensembl_gene_id: Shew_0591
symbol: Shew_0591
gene_biotype: protein_coding
description:
  PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: son:SO0882 oxidoreductase, GMC family.


ensembl_gene_id: Shew_0593
symbol: Shew_0593
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3281 ABC transporter-related protein.


ensembl_gene_id: Shew_0596
symbol: Shew_0596
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: cps:CPS_1439 methyl-accepting chemotaxis protein.


ensembl_gene_id: Shew_0598
symbol: Shew_0598
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_3275 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family.


ensembl_gene_id: Shew_0603
symbol: Shew_0603
gene_biotype: protein_coding
description:
  PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: she:Shewmr4_0739 glutathione-dependent formaldehyde-activating, GFA.


ensembl_gene_id: Shew_0604
symbol: rhlE
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: Shew_0607
symbol: Shew_0607
gene_biotype: protein_coding
description:
  PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_0508 4Fe-4S ferredoxin, iron-sulfur binding domain protein.


ensembl_gene_id: Shew_0608
symbol: Shew_0608
gene_biotype: protein_coding
description:
  PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: she:Shewmr4_3444 twin-arginine translocation pathway signal; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Shew_0609
symbol: Shew_0609
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: son:SO4157 DNA-binding response regulator.


ensembl_gene_id: Shew_0610
symbol: Shew_0610
gene_biotype: protein_coding
description:
  Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4155 sensor histidine kinase.


ensembl_gene_id: Shew_0613
symbol: Shew_0613
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3213 ABC transporter-related protein; TIGRFAM: ABC transporter, transmembrane region, type 1; PFAM: ABC transporter, transmembrane region; ABC transporter-related protein; SMART: AAA ATPase.


ensembl_gene_id: Shew_0614
symbol: Shew_0614
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_3126 ABC transporter-related protein; TIGRFAM: ABC transporter, transmembrane region, type 1; PFAM: ABC transporter-related protein; SMART: AAA ATPase.


ensembl_gene_id: Shew_0615
symbol: Shew_0615
gene_biotype: protein_coding
description:
  L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Shew_0620
symbol: Shew_0620
gene_biotype: protein_coding
description:
  PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: sfr:Sfri_3269 ion transport 2 domain protein.


ensembl_gene_id: Shew_0625
symbol: speE
gene_biotype: protein_coding
description:
  Spermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: Shew_0628
symbol: glnE
gene_biotype: protein_coding
description:
  (Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]


ensembl_gene_id: Shew_0630
symbol: Shew_0630
gene_biotype: protein_coding
description:
  PFAM: conserved hypothetical protein 245; KEGG: vpa:VP1159 putative ABC transport system permease protein.


ensembl_gene_id: Shew_0638
symbol: Shew_0638
gene_biotype: protein_coding
description:
  PFAM: cell surface receptor IPT/TIG domain protein; KEGG: hwa:HQ3601A cell surface calcium-binding acidic-repeat protein.


ensembl_gene_id: Shew_0640
symbol: Shew_0640
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: mba:Mbar_A2604 TPR repeat.


ensembl_gene_id: Shew_0642
symbol: Shew_0642
gene_biotype: protein_coding
description:
  PFAM: type II secretion system protein; KEGG: bxe:Bxe_B2923 putative type II secretion system protein F.


ensembl_gene_id: Shew_0643
symbol: Shew_0643
gene_biotype: protein_coding
description:
  PFAM: type II secretion system protein; KEGG: bxe:Bxe_B2922 putative type II secretion system protein F.


ensembl_gene_id: Shew_0644
symbol: Shew_0644
gene_biotype: protein_coding
description:
  FHA domain containing protein; PFAM: Forkhead-associated protein; type II secretion system protein E; KEGG: bxe:Bxe_B2921 type II/IV secretion system protein E.


ensembl_gene_id: Shew_0645
symbol: Shew_0645
gene_biotype: protein_coding
description:
  PFAM: type II and III secretion system protein; KEGG: bxe:Bxe_B2920 putative type II and III secretion system outermembrane protein, secretin; Belongs to the bacterial secretin family.


ensembl_gene_id: Shew_0656
symbol: Shew_0656
gene_biotype: protein_coding
description:
  Transcriptional regulator, NifA subfamily, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; GAF domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_3090 transcriptional regulator, NifA subfamily, fis family.


ensembl_gene_id: Shew_0658
symbol: lpxL
gene_biotype: protein_coding
description:
  Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: Shew_0659
symbol: hldE
gene_biotype: protein_coding
description:
  D-beta-D-heptose 1-phosphate adenylyltransferase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.


ensembl_gene_id: Shew_0662
symbol: Shew_0662
gene_biotype: protein_coding
description:
  NAD(P) transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: Shew_0664
symbol: Shew_0664
gene_biotype: protein_coding
description:
  PFAM: alanine dehydrogenase/PNT domain protein; KEGG: abo:ABO_1329 pyridine nucleotide transhydrogenase A subunit.


ensembl_gene_id: Shew_0665
symbol: Shew_0665
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.


ensembl_gene_id: Shew_0666
symbol: cysI
gene_biotype: protein_coding
description:
  Sulfite reductase (NADPH) beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: Shew_0667
symbol: cysH
gene_biotype: protein_coding
description:
  Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: Shew_0669
symbol: Shew_0669
gene_biotype: protein_coding
description:
  Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cps:CPS_2601 antioxidant, AhpC/Tsa family.


ensembl_gene_id: Shew_0671
symbol: Shew_0671
gene_biotype: protein_coding
description:
  Phospholipase A(1); Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: Shew_0672
symbol: Shew_0672
gene_biotype: protein_coding
description:
  TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shm:Shewmr7_0899 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.


ensembl_gene_id: Shew_0674
symbol: Shew_0674
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3067 major facilitator superfamily MFS_1.


ensembl_gene_id: Shew_0680
symbol: Shew_0680
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pfl:PFL_5747 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0687
symbol: Shew_0687
gene_biotype: protein_coding
description:
  PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein.


ensembl_gene_id: Shew_0688
symbol: Shew_0688
gene_biotype: protein_coding
description:
  PFAM: nitroreductase; KEGG: son:SO3715 dihydropteridine reductase/oxygen-insensitive NAD(P)H nitroreductase.


ensembl_gene_id: Shew_0690
symbol: Shew_0690
gene_biotype: protein_coding
description:
  PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_0969 endonuclease/exonuclease/phosphatase.


ensembl_gene_id: Shew_0695
symbol: Shew_0695
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF331; KEGG: shm:Shewmr7_0498 protein of unknown function DUF331.


ensembl_gene_id: Shew_0696
symbol: rbsK
gene_biotype: protein_coding
description:
  Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: Shew_0700
symbol: Shew_0700
gene_biotype: protein_coding
description:
  PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: shm:Shewmr7_3276 pirin domain protein domain protein; Belongs to the pirin family.


ensembl_gene_id: Shew_0703
symbol: Shew_0703
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; KEGG: pha:PSHAa1150 response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase).


ensembl_gene_id: Shew_0706
symbol: Shew_0706
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: son:SO0510 oxidoreductase, short-chain dehydrogenase/reductase family.


ensembl_gene_id: Shew_0709
symbol: katG
gene_biotype: protein_coding
description:
  Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.


ensembl_gene_id: Shew_0710
symbol: Shew_0710
gene_biotype: protein_coding
description:
  Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: Shew_0712
symbol: Shew_0712
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_0840 ABC transporter-related protein.


ensembl_gene_id: Shew_0713
symbol: Shew_0713
gene_biotype: protein_coding
description:
  PFAM: transport system permease protein; KEGG: she:Shewmr4_0841 transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: Shew_0714
symbol: cobT
gene_biotype: protein_coding
description:
  Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: Shew_0715
symbol: cobS
gene_biotype: protein_coding
description:
  Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: Shew_0716
symbol: Shew_0716
gene_biotype: protein_coding
description:
  Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: Shew_0717
symbol: cobQ
gene_biotype: protein_coding
description:
  Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.


ensembl_gene_id: Shew_0718
symbol: Shew_0718
gene_biotype: protein_coding
description:
  cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: Shew_0721
symbol: Shew_0721
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sfr:Sfri_0897 efflux transporter, RND family, MFP subunit.


ensembl_gene_id: Shew_0723
symbol: Shew_0723
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3159 ABC transporter-related protein.


ensembl_gene_id: Shew_0726
symbol: Shew_0726
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: shm:Shewmr7_3156 two component, sigma54 specific, transcriptional regulator, fis family.


ensembl_gene_id: Shew_0727
symbol: Shew_0727
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3155 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_0729
symbol: Shew_0729
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ppr:PBPRA1421 putative NADH oxidase.


ensembl_gene_id: Shew_0730
symbol: Shew_0730
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: ppr:PBPRA1422 conserved hypothetical protein.


ensembl_gene_id: Shew_0731
symbol: Shew_0731
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: pat:Patl_2106 protein of unknown function DUF395, YeeE/YedE.


ensembl_gene_id: Shew_0732
symbol: Shew_0732
gene_biotype: protein_coding
description:
  KEGG: pfo:Pfl_3508 putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.


ensembl_gene_id: Shew_0735
symbol: Shew_0735
gene_biotype: protein_coding
description:
  Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.


ensembl_gene_id: Shew_0737
symbol: Shew_0737
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; regulatory protein, MarR; KEGG: shm:Shewmr7_3265 transcriptional regulator, MarR family with acetyltransferase activity.


ensembl_gene_id: Shew_0738
symbol: Shew_0738
gene_biotype: protein_coding
description:
  Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: Shew_0740
symbol: Shew_0740
gene_biotype: protein_coding
description:
  KEGG: ecp:ECP_1757 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: Shew_0743
symbol: Shew_0743
gene_biotype: protein_coding
description:
  PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3259 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Shew_0744
symbol: Shew_0744
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: shm:Shewmr7_3258 protein of unknown function DUF306, MetA and HslJ.


ensembl_gene_id: Shew_0746
symbol: Shew_0746
gene_biotype: protein_coding
description:
  Diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_3256 GGDEF domain protein.


ensembl_gene_id: Shew_0751
symbol: metK
gene_biotype: protein_coding
description:
  Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: Shew_0752
symbol: Shew_0752
gene_biotype: protein_coding
description:
  Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: Shew_0753
symbol: epd
gene_biotype: protein_coding
description:
  D-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: Shew_0754
symbol: pgk
gene_biotype: protein_coding
description:
  PFAM: phosphoglycerate kinase; KEGG: she:Shewmr4_0775 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.


ensembl_gene_id: Shew_0755
symbol: Shew_0755
gene_biotype: protein_coding
description:
  Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.


ensembl_gene_id: Shew_0756
symbol: Shew_0756
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF481; KEGG: shm:Shewmr7_3246 protein of unknown function DUF481.


ensembl_gene_id: Shew_0757
symbol: Shew_0757
gene_biotype: protein_coding
description:
  Putative transcriptional regulator, CadC; KEGG: she:Shewmr4_0779 response regulator receiver protein.


ensembl_gene_id: Shew_0760
symbol: Shew_0760
gene_biotype: protein_coding
description:
  Lysine decarboxylase transcriptional regulator, CadC; PFAM: transcriptional regulator domain protein; KEGG: son:SO0940 transcriptional regulator-related protein.


ensembl_gene_id: Shew_0763
symbol: Shew_0763
gene_biotype: protein_coding
description:
  Putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; KEGG: shm:Shewmr7_3237 putative PAS/PAC sensor protein.


ensembl_gene_id: Shew_0765
symbol: Shew_0765
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3235 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_0766
symbol: Shew_0766
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: she:Shewmr4_0789 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_0767
symbol: srmB
gene_biotype: protein_coding
description:
  DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: Shew_0768
symbol: Shew_0768
gene_biotype: protein_coding
description:
  Methyltransferase small; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: Shew_0769
symbol: Shew_0769
gene_biotype: protein_coding
description:
  Branched-chain amino acid transport system II carrier protein; Component of the transport system for branched-chain amino acids.


ensembl_gene_id: Shew_0770
symbol: xerD
gene_biotype: protein_coding
description:
  Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.


ensembl_gene_id: Shew_0771
symbol: Shew_0771
gene_biotype: protein_coding
description:
  Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: Shew_0772
symbol: Shew_0772
gene_biotype: protein_coding
description:
  TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: shm:Shewmr7_3226 single-stranded-DNA-specific exonuclease RecJ.


ensembl_gene_id: Shew_0773
symbol: fbp
gene_biotype: protein_coding
description:
  PFAM: Inositol phosphatase/fructose-1,6-bisphosphatase; KEGG: shm:Shewmr7_3373 inositol phosphatase/fructose-1,6-bisphosphatase.


ensembl_gene_id: Shew_0774
symbol: Shew_0774
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shm:Shewmr7_3372 peptidase S9B, dipeptidylpeptidase IV domain protein.


ensembl_gene_id: Shew_0777
symbol: Shew_0777
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3371 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_0779
symbol: Shew_0779
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_0653 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.


ensembl_gene_id: Shew_0780
symbol: Shew_0780
gene_biotype: protein_coding
description:
  PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: shm:Shewmr7_3368 succinylglutamate desuccinylase/aspartoacylase.


ensembl_gene_id: Shew_0781
symbol: Shew_0781
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: sfr:Sfri_0513 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family.


ensembl_gene_id: Shew_0782
symbol: Shew_0782
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, AsnC/Lrp family; KEGG: shm:Shewmr7_0826 transcriptional regulator, AsnC family.


ensembl_gene_id: Shew_0783
symbol: Shew_0783
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Shew_0785
symbol: Shew_0785
gene_biotype: protein_coding
description:
  PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_0810 methyltransferase type 12.


ensembl_gene_id: Shew_0787
symbol: Shew_0787
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shm:Shewmr7_3216 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein.


ensembl_gene_id: Shew_0789
symbol: Shew_0789
gene_biotype: protein_coding
description:
  PFAM: Mg2+ transporter protein, CorA family protein; KEGG: sfr:Sfri_0943 Mg2 transporter protein, CorA family protein.


ensembl_gene_id: Shew_0792
symbol: Shew_0792
gene_biotype: protein_coding
description:
  Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: Shew_0793
symbol: Shew_0793
gene_biotype: protein_coding
description:
  PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0800 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.


ensembl_gene_id: Shew_0794
symbol: Shew_0794
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: spt:SPA1005 hypothetical protein.


ensembl_gene_id: Shew_0801
symbol: rlmC
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumB; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.


ensembl_gene_id: Shew_0802
symbol: Shew_0802
gene_biotype: protein_coding
description:
  TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: sfr:Sfri_0580 chromate transporter, chromate ion transporter (CHR) family protein.


ensembl_gene_id: Shew_0803
symbol: Shew_0803
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_0818 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_0804
symbol: Shew_0804
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3204 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_0806
symbol: Shew_0806
gene_biotype: protein_coding
description:
  PFAM: MltA-interacting MipA family protein; KEGG: shm:Shewmr7_3202 MltA-interacting MipA family protein.


ensembl_gene_id: Shew_0807
symbol: Shew_0807
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: shm:Shewmr7_3201 LPXTG-motif cell wall anchor domain; Belongs to the peptidase S8 family.


ensembl_gene_id: Shew_0808
symbol: Shew_0808
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_0630 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_0809
symbol: Shew_0809
gene_biotype: protein_coding
description:
  TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: she:Shewmr4_0825 formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.


ensembl_gene_id: Shew_0810
symbol: Shew_0810
gene_biotype: protein_coding
description:
  PFAM: pentapeptide repeat protein; Ion transport 2 domain protein,; KEGG: vvy:VV0782 putative potassium channel protein.


ensembl_gene_id: Shew_0811
symbol: prfB
gene_biotype: protein_coding
description:
  Bacterial peptide chain release factor 2 (bRF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: Shew_0812
symbol: lysS
gene_biotype: protein_coding
description:
  TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: sdn:Sden_3127 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: Shew_0813
symbol: Shew_0813
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1231 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_0814
symbol: Shew_0814
gene_biotype: protein_coding
description:
  PFAM: pseudouridine synthase; KEGG: cps:CPS_1154 RNA pseudouridine synthase family protein; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Shew_0815
symbol: nagB
gene_biotype: protein_coding
description:
  Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.


ensembl_gene_id: Shew_0819
symbol: Shew_0819
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1696; KEGG: shm:Shewmr7_0829 protein of unknown function DUF1696.


ensembl_gene_id: Shew_0823
symbol: Shew_0823
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_0776 transcriptional regulator, LysR family protein.


ensembl_gene_id: Shew_0825
symbol: rpiA
gene_biotype: protein_coding
description:
  Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: Shew_0827
symbol: Shew_0827
gene_biotype: protein_coding
description:
  Peptidyl-prolyl cis-trans isomerase, cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: Shew_0828
symbol: Shew_0828
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1046 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_0836
symbol: Shew_0836
gene_biotype: protein_coding
description:
  TIGRFAM: Prokaryotic membrane lipoprotein lipid attachment site; KEGG: shm:Shewmr7_0935 hypothetical protein.


ensembl_gene_id: Shew_0837
symbol: Shew_0837
gene_biotype: protein_coding
description:
  PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO1061 TPR domain protein.


ensembl_gene_id: Shew_0840
symbol: Shew_0840
gene_biotype: protein_coding
description:
  Peptidylprolyl isomerase, FKBP-type; PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: shm:Shewmr7_0940 peptidylprolyl isomerase, FKBP-type.


ensembl_gene_id: Shew_0841
symbol: Shew_0841
gene_biotype: protein_coding
description:
  PFAM: uncharacterized conserved protein UCP006287; KEGG: son:SO3983 hypothetical protein; Belongs to the UPF0231 family.


ensembl_gene_id: Shew_0842
symbol: Shew_0842
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: shm:Shewmr7_3365 two component transcriptional regulator, LuxR family.


ensembl_gene_id: Shew_0843
symbol: Shew_0843
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, nitrate/nitrite-specific, NarQ; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shm:Shewmr7_3364 signal transduction histidine kinase, nitrate/nitrite-specific, NarQ.


ensembl_gene_id: Shew_0844
symbol: nrfA
gene_biotype: protein_coding
description:
  Respiratory nitrite reductase (cytochrome; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.


ensembl_gene_id: Shew_0846
symbol: Shew_0846
gene_biotype: protein_coding
description:
  PFAM: nitrogen regulatory protein P-II; KEGG: sfr:Sfri_0623 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.


ensembl_gene_id: Shew_0847
symbol: Shew_0847
gene_biotype: protein_coding
description:
  PFAM: Rh family protein/ammonium transporter; KEGG: shm:Shewmr7_0592 Rh family protein/ammonium transporter.


ensembl_gene_id: Shew_0849
symbol: Shew_0849
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_0594 tetratricopeptide TPR_2 repeat protein.


ensembl_gene_id: Shew_0850
symbol: Shew_0850
gene_biotype: protein_coding
description:
  Hypothetical protein; KEGG: sfr:Sfri_0627 ABC-type amino acid transport/signal transduction systems.


ensembl_gene_id: Shew_0851
symbol: Shew_0851
gene_biotype: protein_coding
description:
  3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: Shew_0853
symbol: Shew_0853
gene_biotype: protein_coding
description:
  ABC transporter-related protein; PFAM: ABC transporter, transmembrane region; ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0597 ABC transporter-related protein.


ensembl_gene_id: Shew_0858
symbol: Shew_0858
gene_biotype: protein_coding
description:
  PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: son:SO0747 ferredoxin--NADP reductase.


ensembl_gene_id: Shew_0859
symbol: Shew_0859
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase, N-terminal domain; KEGG: son:SO0746 glutathione S-transferase family protein.


ensembl_gene_id: Shew_0861
symbol: Shew_0861
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein, family 1; KEGG: shm:Shewmr7_0606 extracellular solute-binding protein, family 1.


ensembl_gene_id: Shew_0862
symbol: Shew_0862
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfr:Sfri_0637 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Shew_0863
symbol: Shew_0863
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sfr:Sfri_0638 ABC transporter-related protein; Belongs to the ABC transporter superfamily.


ensembl_gene_id: Shew_0864
symbol: Shew_0864
gene_biotype: protein_coding
description:
  TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: son:SO0740 melanin biosynthesis protein TyrA, putative.


ensembl_gene_id: Shew_0868
symbol: Shew_0868
gene_biotype: protein_coding
description:
  Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: son:SO3653 octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.


ensembl_gene_id: Shew_0869
symbol: rplU
gene_biotype: protein_coding
description:
  LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: Shew_0870
symbol: rpmA
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L27; KEGG: son:SO3651 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.


ensembl_gene_id: Shew_0871
symbol: obg
gene_biotype: protein_coding
description:
  GTP1/OBG sub domain protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: Shew_0874
symbol: Shew_0874
gene_biotype: protein_coding
description:
  Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: Shew_0876
symbol: Shew_0876
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO3642 methyl-accepting chemotaxis protein.


ensembl_gene_id: Shew_0877
symbol: apaH
gene_biotype: protein_coding
description:
  Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: Shew_0879
symbol: rsmA
gene_biotype: protein_coding
description:
  Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: Shew_0880
symbol: pdxA
gene_biotype: protein_coding
description:
  4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: Shew_0881
symbol: surA
gene_biotype: protein_coding
description:
  PpiC-type peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: Shew_0882
symbol: lptD
gene_biotype: protein_coding
description:
  Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: Shew_0885
symbol: djlA
gene_biotype: protein_coding
description:
  Heat shock protein DnaJ domain protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: Shew_0887
symbol: Shew_0887
gene_biotype: protein_coding
description:
  PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shm:Shewmr7_3107 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein.


ensembl_gene_id: Shew_0890
symbol: Shew_0890
gene_biotype: protein_coding
description:
  PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3016 secretion protein HlyD family protein.


ensembl_gene_id: Shew_0891
symbol: Shew_0891
gene_biotype: protein_coding
description:
  KEGG: vch:VC1406 methyl-accepting chemotaxis protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_0892
symbol: Shew_0892
gene_biotype: protein_coding
description:
  PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3100 AAA ATPase, central domain protein.


ensembl_gene_id: Shew_0894
symbol: Shew_0894
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1289; KEGG: she:Shewmr4_3008 protein of unknown function DUF1289.


ensembl_gene_id: Shew_0895
symbol: Shew_0895
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3007 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_0896
symbol: Shew_0896
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3087 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_0899
symbol: Shew_0899
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sdn:Sden_3019 regulatory protein, LysR; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Shew_0900
symbol: Shew_0900
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sdn:Sden_3018 acyl-CoA dehydrogenase-like protein.


ensembl_gene_id: Shew_0901
symbol: Shew_0901
gene_biotype: protein_coding
description:
  PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region.


ensembl_gene_id: Shew_0907
symbol: Shew_0907
gene_biotype: protein_coding
description:
  PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator.


ensembl_gene_id: Shew_0908
symbol: Shew_0908
gene_biotype: protein_coding
description:
  PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: sfr:Sfri_1135 OmpA/MotB domain protein.


ensembl_gene_id: Shew_0913
symbol: Shew_0913
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_3081 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Shew_0916
symbol: Shew_0916
gene_biotype: protein_coding
description:
  Pseudouridine synthase; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: sdn:Sden_2876 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Shew_0919
symbol: Shew_0919
gene_biotype: protein_coding
description:
  Diguanylate phosphodiesterase; PFAM: EAL domain protein; phosphotransferase system, EIIC; KEGG: shm:Shewmr7_3254 diguanylate phosphodiesterase.


ensembl_gene_id: Shew_0920
symbol: Shew_0920
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_2826 major facilitator superfamily MFS_1.


ensembl_gene_id: Shew_0922
symbol: Shew_0922
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: vch:VC1643 methyl-accepting chemotaxis protein.


ensembl_gene_id: Shew_0923
symbol: valS
gene_biotype: protein_coding
description:
  valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: Shew_0924
symbol: Shew_0924
gene_biotype: protein_coding
description:
  PFAM: DNA polymerase III chi subunit, HolC; KEGG: shm:Shewmr7_1202 DNA polymerase III chi subunit, HolC.


ensembl_gene_id: Shew_0928
symbol: Shew_0928
gene_biotype: protein_coding
description:
  PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: she:Shewmr4_3024 transposase IS116/IS110/IS902 family protein.


ensembl_gene_id: Shew_0931
symbol: Shew_0931
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF52; KEGG: hch:HCH_05946 predicted dioxygenase; Belongs to the MEMO1 family.


ensembl_gene_id: Shew_0934
symbol: Shew_0934
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: ppr:PBPRA2309 hypothetical protein.


ensembl_gene_id: Shew_0935
symbol: Shew_0935
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: shm:Shewmr7_0825 protease-associated PA domain protein; Belongs to the peptidase S8 family.


ensembl_gene_id: Shew_0936
symbol: Shew_0936
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: son:SO3800 serine protease, subtilase family.


ensembl_gene_id: Shew_0937
symbol: Shew_0937
gene_biotype: protein_coding
description:
  Transcriptional regulator, CadC; PFAM: transcriptional regulator domain protein; KEGG: she:Shewmr4_2883 transcriptional regulator domain protein.


ensembl_gene_id: Shew_0939
symbol: pepA
gene_biotype: protein_coding
description:
  PepA aminopeptidase. Metallo peptidase. MEROPS family M17; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: Shew_0945
symbol: Shew_0945
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1449; KEGG: shm:Shewmr7_2900 protein of unknown function DUF1449.


ensembl_gene_id: Shew_0947
symbol: Shew_0947
gene_biotype: protein_coding
description:
  Carboxypeptidase Taq; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: Shew_0949
symbol: Shew_0949
gene_biotype: protein_coding
description:
  Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sfr:Sfri_3069 redoxin domain protein.


ensembl_gene_id: Shew_0950
symbol: Shew_0950
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO1383 ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family.


ensembl_gene_id: Shew_0953
symbol: Shew_0953
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: sde:Sde_3481 conserved hypothetical drug transport transmembrane protein.


ensembl_gene_id: Shew_0956
symbol: Shew_0956
gene_biotype: protein_coding
description:
  PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1390 peptidyl-prolyl cis-trans isomerase, FKBP-type.


ensembl_gene_id: Shew_0957
symbol: Shew_0957
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1294; KEGG: shm:Shewmr7_2883 protein of unknown function DUF1294.


ensembl_gene_id: Shew_0964
symbol: Shew_0964
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF861, cupin_3; KEGG: shm:Shewmr7_3011 protein of unknown function DUF861, cupin_3.


ensembl_gene_id: Shew_0965
symbol: Shew_0965
gene_biotype: protein_coding
description:
  TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2928 methylmalonate-semialdehyde dehydrogenase.


ensembl_gene_id: Shew_0966
symbol: Shew_0966
gene_biotype: protein_coding
description:
  PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Shew_0967
symbol: Shew_0967
gene_biotype: protein_coding
description:
  PFAM: aldehyde dehydrogenase; KEGG: sfr:Sfri_3021 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family.


ensembl_gene_id: Shew_0968
symbol: Shew_0968
gene_biotype: protein_coding
description:
  3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese domain protein; KEGG: shm:Shewmr7_3006 3-mercaptopyruvate sulfurtransferase.


ensembl_gene_id: Shew_0970
symbol: Shew_0970
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family with cupin sensor; PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_3003 transcriptional regulator, XRE family with cupin sensor.


ensembl_gene_id: Shew_0973
symbol: Shew_0973
gene_biotype: protein_coding
description:
  Extracellular solute-binding protein, family 1; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: Shew_0974
symbol: potA
gene_biotype: protein_coding
description:
  Spermidine/putrescine ABC transporter ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: Shew_0975
symbol: Shew_0975
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2998 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Shew_0976
symbol: Shew_0976
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2997 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Shew_0979
symbol: Shew_0979
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_3384 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.


ensembl_gene_id: Shew_0980
symbol: Shew_0980
gene_biotype: protein_coding
description:
  PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: pat:Patl_2104 multi-sensor hybrid histidine kinase.


ensembl_gene_id: Shew_0991
symbol: Shew_0991
gene_biotype: protein_coding
description:
  PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: psb:Psyr_2668 helix-turn-helix, fis-type.


ensembl_gene_id: Shew_0992
symbol: Shew_0992
gene_biotype: protein_coding
description:
  PFAM: BsuBIPstI restriction endonuclease domain protein; KEGG: ssn:SSO_1584 putative restriction endonuclease.


ensembl_gene_id: Shew_0995
symbol: Shew_0995
gene_biotype: protein_coding
description:
  PFAM: phage integrase family protein; KEGG: bxe:Bxe_A3110 putative phage integrase; Belongs to the 'phage' integrase family.


ensembl_gene_id: Shew_0996
symbol: rpoD
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: Shew_0997
symbol: dnaG
gene_biotype: protein_coding
description:
  DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: Shew_0999
symbol: rpsU
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S21; KEGG: shm:Shewmr7_2987 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.


ensembl_gene_id: Shew_1000
symbol: tsaD
gene_biotype: protein_coding
description:
  O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: Shew_1001
symbol: plsY
gene_biotype: protein_coding
description:
  Acyl-phosphate glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: Shew_1002
symbol: Shew_1002
gene_biotype: protein_coding
description:
  Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: Shew_1003
symbol: Shew_1003
gene_biotype: protein_coding
description:
  TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase.


ensembl_gene_id: Shew_1004
symbol: uppP
gene_biotype: protein_coding
description:
  Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: Shew_1006
symbol: Shew_1006
gene_biotype: protein_coding
description:
  PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: vpa:VPA1470 hypothetical protein.


ensembl_gene_id: Shew_1008
symbol: cca
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: Shew_1009
symbol: Shew_1009
gene_biotype: protein_coding
description:
  PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2896 peptidoglycan-binding domain 1 protein.


ensembl_gene_id: Shew_1012
symbol: hemL
gene_biotype: protein_coding
description:
  TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: shm:Shewmr7_2975 glutamate-1-semialdehyde-2,1-aminomutase.


ensembl_gene_id: Shew_1013
symbol: Shew_1013
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2974 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.


ensembl_gene_id: Shew_1014
symbol: Shew_1014
gene_biotype: protein_coding
description:
  Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: cvi:CV0910 hypothetical protein.


ensembl_gene_id: Shew_1015
symbol: Shew_1015
gene_biotype: protein_coding
description:
  PFAM: Cl- channel, voltage-gated family protein; KEGG: shm:Shewmr7_2973 Cl-channel, voltage-gated family protein.


ensembl_gene_id: Shew_1017
symbol: erpA
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG.


ensembl_gene_id: Shew_1020
symbol: anmK
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: Shew_1021
symbol: Shew_1021
gene_biotype: protein_coding
description:
  PFAM: peptidase M23B; Opacity-associated protein A, N-terminal domain protein; KEGG: shm:Shewmr7_2963 peptidase M23B.


ensembl_gene_id: Shew_1022
symbol: tyrS
gene_biotype: protein_coding
description:
  tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.


ensembl_gene_id: Shew_1024
symbol: Shew_1024
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_2959 protein of unknown function UPF0126.


ensembl_gene_id: Shew_1026
symbol: Shew_1026
gene_biotype: protein_coding
description:
  PFAM: cobalamin biosynthesis protein CbiB; KEGG: she:Shewmr4_2875 cobalamin biosynthesis protein CbiB.


ensembl_gene_id: Shew_1027
symbol: mtnN
gene_biotype: protein_coding
description:
  Methylthioadenosine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.


ensembl_gene_id: Shew_1031
symbol: Shew_1031
gene_biotype: protein_coding
description:
  TIGRFAM: glutamate synthase, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_2873 glutamate synthase, small subunit.


ensembl_gene_id: Shew_1032
symbol: Shew_1032
gene_biotype: protein_coding
description:
  PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: she:Shewmr4_2872 glutamate synthase (ferredoxin).


ensembl_gene_id: Shew_1033
symbol: Shew_1033
gene_biotype: protein_coding
description:
  KEGG: son:SO1326 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.


ensembl_gene_id: Shew_1035
symbol: Shew_1035
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1328 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_1037
symbol: mutH
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: Shew_1038
symbol: rppH
gene_biotype: protein_coding
description:
  NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: Shew_1039
symbol: Shew_1039
gene_biotype: protein_coding
description:
  PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: shm:Shewmr7_2946 PTSINtr with GAF domain, PtsP; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: Shew_1041
symbol: thyA
gene_biotype: protein_coding
description:
  Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: Shew_1042
symbol: nhaA
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: Shew_1045
symbol: Shew_1045
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF339; KEGG: shm:Shewmr7_2939 protein of unknown function DUF339.


ensembl_gene_id: Shew_1048
symbol: Shew_1048
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO1342 RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Shew_1049
symbol: Shew_1049
gene_biotype: protein_coding
description:
  Anti sigma-E protein, RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish  [...]


ensembl_gene_id: Shew_1051
symbol: Shew_1051
gene_biotype: protein_coding
description:
  PFAM: Positive regulator of sigma(E), RseC/MucC; KEGG: sdn:Sden_2769 positive regulator of sigma(E), RseC/MucC.


ensembl_gene_id: Shew_1052
symbol: lepA
gene_biotype: protein_coding
description:
  GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: Shew_1053
symbol: Shew_1053
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2931 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Belongs to the peptidase S26 family.


ensembl_gene_id: Shew_1054
symbol: rnc
gene_biotype: protein_coding
description:
  RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: Shew_1055
symbol: era
gene_biotype: protein_coding
description:
  GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: Shew_1057
symbol: pdxJ
gene_biotype: protein_coding
description:
  Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: Shew_1058
symbol: acpS
gene_biotype: protein_coding
description:
  Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: Shew_1060
symbol: Shew_1060
gene_biotype: protein_coding
description:
  PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: sfr:Sfri_2923 protein of unknown function DUF21.


ensembl_gene_id: Shew_1062
symbol: ffh
gene_biotype: protein_coding
description:
  Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...]


ensembl_gene_id: Shew_1063
symbol: rpsP
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein S16; KEGG: sdn:Sden_2754 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.


ensembl_gene_id: Shew_1064
symbol: rimM
gene_biotype: protein_coding
description:
  16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: Shew_1065
symbol: trmD
gene_biotype: protein_coding
description:
  tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: Shew_1066
symbol: rplS
gene_biotype: protein_coding
description:
  LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: Shew_1068
symbol: Shew_1068
gene_biotype: protein_coding
description:
  TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: sfr:Sfri_2915 chorismate mutase.


ensembl_gene_id: Shew_1070
symbol: Shew_1070
gene_biotype: protein_coding
description:
  PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sfr:Sfri_3608 oxidoreductase FAD-binding domain protein.


ensembl_gene_id: Shew_1072
symbol: Shew_1072
gene_biotype: protein_coding
description:
  TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: shm:Shewmr7_2910 chorismate mutase.


ensembl_gene_id: Shew_1073
symbol: Shew_1073
gene_biotype: protein_coding
description:
  TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_1203 sigma 54 modulation protein/ribosomal protein S30EA.


ensembl_gene_id: Shew_1078
symbol: Shew_1078
gene_biotype: protein_coding
description:
  PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO3417 peptidyl-prolyl cis-trans isomerase SlyD.


ensembl_gene_id: Shew_1079
symbol: Shew_1079
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1209 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family.


ensembl_gene_id: Shew_1080
symbol: thrB
gene_biotype: protein_coding
description:
  Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: Shew_1081
symbol: Shew_1081
gene_biotype: protein_coding
description:
  KEGG: son:SO3413 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.


ensembl_gene_id: Shew_1083
symbol: nfo
gene_biotype: protein_coding
description:
  Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: Shew_1084
symbol: Shew_1084
gene_biotype: protein_coding
description:
  KEGG: mag:amb3313 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein.


ensembl_gene_id: Shew_1086
symbol: Shew_1086
gene_biotype: protein_coding
description:
  PFAM: Hemerythrin HHE cation binding domain protein; KEGG: sdn:Sden_2737 hemerythrin HHE cation binding region.


ensembl_gene_id: Shew_1088
symbol: pgi
gene_biotype: protein_coding
description:
  PFAM: phosphoglucose isomerase (PGI); KEGG: son:SO3547 glucose-6-phosphate isomerase; Belongs to the GPI family.


ensembl_gene_id: Shew_1089
symbol: tal
gene_biotype: protein_coding
description:
  Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: Shew_1090
symbol: Shew_1090
gene_biotype: protein_coding
description:
  PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: sfr:Sfri_2899 OmpA/MotB domain protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.


ensembl_gene_id: Shew_1091
symbol: Shew_1091
gene_biotype: protein_coding
description:
  Phosphoketolase; PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: shm:Shewmr7_3047 phosphoketolase.


ensembl_gene_id: Shew_1092
symbol: Shew_1092
gene_biotype: protein_coding
description:
  TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: dps:DP1274 probable sodium/alanine symporter.


ensembl_gene_id: Shew_1093
symbol: Shew_1093
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF328; KEGG: ppr:PBPRA0561 hypothetical protein; Belongs to the UPF0246 family.


ensembl_gene_id: Shew_1097
symbol: murJ
gene_biotype: protein_coding
description:
  Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: Shew_1098
symbol: Shew_1098
gene_biotype: protein_coding
description:
  TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; Belongs to the ribF family.


ensembl_gene_id: Shew_1099
symbol: ileS
gene_biotype: protein_coding
description:
  Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: Shew_1100
symbol: lspA
gene_biotype: protein_coding
description:
  Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: Shew_1101
symbol: Shew_1101
gene_biotype: protein_coding
description:
  PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: shm:Shewmr7_3037 peptidylprolyl isomerase, FKBP-type.


ensembl_gene_id: Shew_1102
symbol: ispH
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.


ensembl_gene_id: Shew_1103
symbol: Shew_1103
gene_biotype: protein_coding
description:
  TIGRFAM: type IV pilus modification protein PilV; KEGG: shm:Shewmr7_3035 type IV pilus modification protein PilV.


ensembl_gene_id: Shew_1110
symbol: Shew_1110
gene_biotype: protein_coding
description:
  PFAM: nitrogen regulatory protein P-II; KEGG: sdn:Sden_2711 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.


ensembl_gene_id: Shew_1111
symbol: Shew_1111
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: son:SO3516 transcriptional regulator, LacI family.


ensembl_gene_id: Shew_1112
symbol: Shew_1112
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3024 TonB-dependent receptor.


ensembl_gene_id: Shew_1115
symbol: Shew_1115
gene_biotype: protein_coding
description:
  beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 20; Carbohydrate-binding, chitobiase/hexosaminidase-type domain protein; glycoside hydrolase, family 20 domain protein; KEGG: she:Shewmr4_2936 beta-N-acetylhexosaminidase.


ensembl_gene_id: Shew_1117
symbol: Shew_1117
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_2704 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. NagA family.


ensembl_gene_id: Shew_1119
symbol: Shew_1119
gene_biotype: protein_coding
description:
  TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_3013 glucose/galactose transporter.


ensembl_gene_id: Shew_1122
symbol: Shew_1122
gene_biotype: protein_coding
description:
  Fe(II) trafficking protein YggX; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.


ensembl_gene_id: Shew_1124
symbol: trmB
gene_biotype: protein_coding
description:
  tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.


ensembl_gene_id: Shew_1128
symbol: Shew_1128
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1256 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_1130
symbol: Shew_1130
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF885; KEGG: shm:Shewmr7_1257 protein of unknown function DUF885.


ensembl_gene_id: Shew_1131
symbol: Shew_1131
gene_biotype: protein_coding
description:
  Coproporphyrinogen III oxidase, anaerobic; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: Shew_1132
symbol: Shew_1132
gene_biotype: protein_coding
description:
  Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: Shew_1134
symbol: Shew_1134
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein; Belongs to the UPF0235 family.


ensembl_gene_id: Shew_1136
symbol: proC
gene_biotype: protein_coding
description:
  Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.


ensembl_gene_id: Shew_1137
symbol: Shew_1137
gene_biotype: protein_coding
description:
  Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.


ensembl_gene_id: Shew_1138
symbol: Shew_1138
gene_biotype: protein_coding
description:
  TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: sfr:Sfri_2859 twitching motility protein.


ensembl_gene_id: Shew_1139
symbol: Shew_1139
gene_biotype: protein_coding
description:
  TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: shm:Shewmr7_1266 twitching motility protein.


ensembl_gene_id: Shew_1140
symbol: hemH
gene_biotype: protein_coding
description:
  Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: Shew_1142
symbol: Shew_1142
gene_biotype: protein_coding
description:
  Putative transcriptional regulator; PFAM: AAA-4 family protein; KEGG: tbd:Tbd_1077 predicted transcriptional regulator.


ensembl_gene_id: Shew_1143
symbol: Shew_1143
gene_biotype: protein_coding
description:
  Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: Shew_1144
symbol: Shew_1144
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF179; KEGG: shm:Shewmr7_1270 protein of unknown function DUF179; Belongs to the UPF0301 (AlgH) family.


ensembl_gene_id: Shew_1149
symbol: Shew_1149
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_0421 transcription regulator, LysR family; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Shew_1154
symbol: Shew_1154
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_1274 protein of unknown function UPF0126.


ensembl_gene_id: Shew_1155
symbol: Shew_1155
gene_biotype: protein_coding
description:
  L-threonine aldolase; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase.


ensembl_gene_id: Shew_1157
symbol: Shew_1157
gene_biotype: protein_coding
description:
  PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0584 alkaline phosphatase; Belongs to the alkaline phosphatase family.


ensembl_gene_id: Shew_1158
symbol: Shew_1158
gene_biotype: protein_coding
description:
  PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0583 alkaline phosphatase; Belongs to the alkaline phosphatase family.


ensembl_gene_id: Shew_1161
symbol: Shew_1161
gene_biotype: protein_coding
description:
  NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: stt:t1709 NADH dehydrogenase.


ensembl_gene_id: Shew_1163
symbol: Shew_1163
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: cps:CPS_1536 efflux transporter, MFP subunit, AcrA/E family; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_1164
symbol: Shew_1164
gene_biotype: protein_coding
description:
  TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: vpa:VPA0471 putative multidrug efflux membrane fusion protein.


ensembl_gene_id: Shew_1165
symbol: Shew_1165
gene_biotype: protein_coding
description:
  PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: ppr:PBPRB1929 putative Cold shock-like protein.


ensembl_gene_id: Shew_1166
symbol: Shew_1166
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; KEGG: shm:Shewmr7_2840 iron-containing alcohol dehydrogenase.


ensembl_gene_id: Shew_1167
symbol: Shew_1167
gene_biotype: protein_coding
description:
  KEGG: son:SO1493 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77.


ensembl_gene_id: Shew_1168
symbol: glgB
gene_biotype: protein_coding
description:
  1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: Shew_1169
symbol: Shew_1169
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2835 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: Shew_1170
symbol: Shew_1170
gene_biotype: protein_coding
description:
  Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: Shew_1171
symbol: glgC
gene_biotype: protein_coding
description:
  Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.


ensembl_gene_id: Shew_1172
symbol: Shew_1172
gene_biotype: protein_coding
description:
  Starch synthase; PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: son:SO1499 glycogen synthase.


ensembl_gene_id: Shew_1174
symbol: Shew_1174
gene_biotype: protein_coding
description:
  PFAM: sulfotransferase; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sfr:Sfri_0890 sulfotransferase.


ensembl_gene_id: Shew_1175
symbol: Shew_1175
gene_biotype: protein_coding
description:
  PFAM: SEC-C motif domain protein; Aspartyl/Asparaginyl beta-hydroxylase; Cupin 2, conserved barrel domain protein; KEGG: sfr:Sfri_0891 sec-C motif domain protein.


ensembl_gene_id: Shew_1177
symbol: Shew_1177
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_1150 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_1178
symbol: Shew_1178
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1149 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_1181
symbol: Shew_1181
gene_biotype: protein_coding
description:
  PFAM: PepSY-associated TM helix domain protein; KEGG: cps:CPS_2723 putative iron-regulated membrane protein.


ensembl_gene_id: Shew_1183
symbol: Shew_1183
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO3472 ABC transporter, ATP-binding protein.


ensembl_gene_id: Shew_1185
symbol: glyA
gene_biotype: protein_coding
description:
  Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: Shew_1186
symbol: nrdR
gene_biotype: protein_coding
description:
  ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: Shew_1187
symbol: Shew_1187
gene_biotype: protein_coding
description:
  Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: Shew_1188
symbol: Shew_1188
gene_biotype: protein_coding
description:
  TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: shm:Shewmr7_1163 riboflavin synthase, alpha subunit.


ensembl_gene_id: Shew_1189
symbol: ribB-2
gene_biotype: protein_coding
description:
  3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.


ensembl_gene_id: Shew_1190
symbol: ribH
gene_biotype: protein_coding
description:
  6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: Shew_1191
symbol: nusB
gene_biotype: protein_coding
description:
  NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: Shew_1192
symbol: thiL
gene_biotype: protein_coding
description:
  Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: Shew_1193
symbol: Shew_1193
gene_biotype: protein_coding
description:
  Phosphatidylglycerophosphatase; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: Shew_1200
symbol: Shew_1200
gene_biotype: protein_coding
description:
  Hpt sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: shm:Shewmr7_1175 multi-sensor hybrid histidine kinase.


ensembl_gene_id: Shew_1201
symbol: rlmD
gene_biotype: protein_coding
description:
  23S rRNA (uracil-5-)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: Shew_1202
symbol: Shew_1202
gene_biotype: protein_coding
description:
  (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: Shew_1203
symbol: Shew_1203
gene_biotype: protein_coding
description:
  TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: shm:Shewmr7_1184 MazG family protein.


ensembl_gene_id: Shew_1204
symbol: pyrG
gene_biotype: protein_coding
description:
  CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: Shew_1205
symbol: eno
gene_biotype: protein_coding
description:
  Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: Shew_1206
symbol: ftsB
gene_biotype: protein_coding
description:
  Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: Shew_1207
symbol: ispD
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).


ensembl_gene_id: Shew_1208
symbol: ispF
gene_biotype: protein_coding
description:
  2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: Shew_1209
symbol: truD
gene_biotype: protein_coding
description:
  Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: Shew_1210
symbol: surE
gene_biotype: protein_coding
description:
  5'-nucleotidase / 3'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.


ensembl_gene_id: Shew_1211
symbol: pcm
gene_biotype: protein_coding
description:
  protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: Shew_1212
symbol: Shew_1212
gene_biotype: protein_coding
description:
  Peptidase M23B; PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: shm:Shewmr7_1193 peptidase M23B.


ensembl_gene_id: Shew_1213
symbol: rpoS
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 70 subunit, RpoD family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: Shew_1214
symbol: mutS
gene_biotype: protein_coding
description:
  DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: Shew_1215
symbol: recA
gene_biotype: protein_coding
description:
  recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: Shew_1217
symbol: alaS
gene_biotype: protein_coding
description:
  alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.


ensembl_gene_id: Shew_1218
symbol: csrA
gene_biotype: protein_coding
description:
  Carbon storage regulator, CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: Shew_1219
symbol: oadG
gene_biotype: protein_coding
description:
  Sodium pump decarboxylases, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.


ensembl_gene_id: Shew_1220
symbol: Shew_1220
gene_biotype: protein_coding
description:
  TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: sfr:Sfri_1066 oxaloacetate decarboxylase alpha subunit.


ensembl_gene_id: Shew_1221
symbol: Shew_1221
gene_biotype: protein_coding
description:
  Sodium ion-translocating decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family.


ensembl_gene_id: Shew_1224
symbol: Shew_1224
gene_biotype: protein_coding
description:
  PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3065 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Shew_1227
symbol: gshA
gene_biotype: protein_coding
description:
  TIGRFAM: glutamate--cysteine ligase; KEGG: son:SO3559 glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.


ensembl_gene_id: Shew_1230
symbol: purE
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: Shew_1231
symbol: Shew_1231
gene_biotype: protein_coding
description:
  PFAM: sigma-70 region 2 domain protein; KEGG: she:Shewmr4_2972 RNA polymerase, sigma-24 subunit, ECF subfamily; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Shew_1239
symbol: Shew_1239
gene_biotype: protein_coding
description:
  PFAM: PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_1218 PepSY-associated TM helix domain protein.


ensembl_gene_id: Shew_1241
symbol: Shew_1241
gene_biotype: protein_coding
description:
  TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: son:SO3403 ribosomal subunit interface protein.


ensembl_gene_id: Shew_1245
symbol: Shew_1245
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cyb:CYB_1948 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_1249
symbol: purK
gene_biotype: protein_coding
description:
  Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: Shew_1257
symbol: Shew_1257
gene_biotype: protein_coding
description:
  PFAM: DNA repair protein RadC; KEGG: son:SO1455 DNA repair protein, RadC family; Belongs to the UPF0758 family.


ensembl_gene_id: Shew_1258
symbol: Shew_1258
gene_biotype: protein_coding
description:
  Phage transcriptional regulator, AlpA; PFAM: Prophage CP4-57 regulatory; KEGG: ilo:IL0640 predicted transcriptional regulator.


ensembl_gene_id: Shew_1259
symbol: Shew_1259
gene_biotype: protein_coding
description:
  Phage transcriptional regulator, AlpA; PFAM: Prophage CP4-57 regulatory; KEGG: vvy:VV0810 predicted transcriptional regulator.


ensembl_gene_id: Shew_1260
symbol: Shew_1260
gene_biotype: protein_coding
description:
  PFAM: DNA methylase N-4/N-6 domain protein; KEGG: cgb:cg1028 putative restriction-modification system: methylase.


ensembl_gene_id: Shew_1267
symbol: Shew_1267
gene_biotype: protein_coding
description:
  PFAM: phage integrase family protein; KEGG: she:Shewmr4_2777 phage integrase family protein; Belongs to the 'phage' integrase family.


ensembl_gene_id: Shew_1268
symbol: smpB
gene_biotype: protein_coding
description:
  SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]


ensembl_gene_id: Shew_1270
symbol: Shew_1270
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0125; KEGG: sfr:Sfri_1096 protein of unknown function UPF0125; Belongs to the UPF0125 (RnfH) family.


ensembl_gene_id: Shew_1271
symbol: bamE
gene_biotype: protein_coding
description:
  SmpA/OmlA domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Shew_1272
symbol: Shew_1272
gene_biotype: protein_coding
description:
  PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: she:Shewmr4_2772 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase.


ensembl_gene_id: Shew_1274
symbol: Shew_1274
gene_biotype: protein_coding
description:
  Diguanylate cyclase; KEGG: son:SO1480 GGDEF family protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein.


ensembl_gene_id: Shew_1276
symbol: Shew_1276
gene_biotype: protein_coding
description:
  TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: she:Shewmr4_2766 isocitrate lyase.


ensembl_gene_id: Shew_1277
symbol: Shew_1277
gene_biotype: protein_coding
description:
  Putative signal transduction protein; PFAM: GAF domain protein; HDOD; KEGG: sdn:Sden_1247 hypothetical protein.


ensembl_gene_id: Shew_1279
symbol: Shew_1279
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF980; KEGG: sfr:Sfri_1105 protein of unknown function DUF980; Belongs to the MtfA family.


ensembl_gene_id: Shew_1284
symbol: Shew_1284
gene_biotype: protein_coding
description:
  Acetyltransferase, GNAT family; PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1289 GCN5-related N-acetyltransferase.


ensembl_gene_id: Shew_1285
symbol: Shew_1285
gene_biotype: protein_coding
description:
  5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_1223 metallophosphoesterase; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: Shew_1286
symbol: Shew_1286
gene_biotype: protein_coding
description:
  PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: shm:Shewmr7_1295 protein of unknown function DUF21.


ensembl_gene_id: Shew_1287
symbol: rlmN
gene_biotype: protein_coding
description:
  Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: Shew_1288
symbol: Shew_1288
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1297 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein.


ensembl_gene_id: Shew_1290
symbol: ispG
gene_biotype: protein_coding
description:
  4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: Shew_1291
symbol: hisS
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1117 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein.


ensembl_gene_id: Shew_1293
symbol: bamB
gene_biotype: protein_coding
description:
  Pyrrolo-quinoline quinone; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Shew_1294
symbol: der
gene_biotype: protein_coding
description:
  Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: Shew_1296
symbol: xseA
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: Shew_1297
symbol: guaB
gene_biotype: protein_coding
description:
  Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: Shew_1299
symbol: tadA
gene_biotype: protein_coding
description:
  tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: Shew_1300
symbol: mltF
gene_biotype: protein_coding
description:
  Lytic transglycosylase, catalytic; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family.


ensembl_gene_id: Shew_1301
symbol: purL
gene_biotype: protein_coding
description:
  Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: Shew_1302
symbol: Shew_1302
gene_biotype: protein_coding
description:
  PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shm:Shewmr7_1310 cytochrome bd ubiquinol oxidase, subunit I.


ensembl_gene_id: Shew_1303
symbol: Shew_1303
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: son:SO3285 cytochrome bd-I oxidase subunit II.


ensembl_gene_id: Shew_1304
symbol: Shew_1304
gene_biotype: protein_coding
description:
  TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: sfr:Sfri_1144 cyd operon protein YbgT.


ensembl_gene_id: Shew_1306
symbol: Shew_1306
gene_biotype: protein_coding
description:
  PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: tma:TM1828 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase.


ensembl_gene_id: Shew_1310
symbol: Shew_1310
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1243 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_1311
symbol: Shew_1311
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: sdn:Sden_1277 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_1312
symbol: Shew_1312
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3278 hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_1313
symbol: Shew_1313
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; KEGG: sdn:Sden_1279 regulatory protein, TetR.


ensembl_gene_id: Shew_1317
symbol: Shew_1317
gene_biotype: protein_coding
description:
  PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: sdn:Sden_1285 protein of unknown function DUF115.


ensembl_gene_id: Shew_1318
symbol: Shew_1318
gene_biotype: protein_coding
description:
  Polysaccharide biosynthesis protein CapD; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: son:SO3271 polysaccharide biosynthesis protein.


ensembl_gene_id: Shew_1319
symbol: Shew_1319
gene_biotype: protein_coding
description:
  PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: sdn:Sden_1287 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: Shew_1321
symbol: Shew_1321
gene_biotype: protein_coding
description:
  PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sdn:Sden_3105 methyltransferase type 12.


ensembl_gene_id: Shew_1322
symbol: Shew_1322
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sdn:Sden_3106 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_1325
symbol: Shew_1325
gene_biotype: protein_coding
description:
  Acetyltransferase-like protein; KEGG: sdn:Sden_3109 acetyltransferases including N-acetylases of ribosomal proteins-like protein.


ensembl_gene_id: Shew_1326
symbol: Shew_1326
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sdn:Sden_3110 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_1328
symbol: Shew_1328
gene_biotype: protein_coding
description:
  PFAM: acylneuraminate cytidylyltransferase; KEGG: sdn:Sden_3112 acylneuraminate cytidylyltransferase.


ensembl_gene_id: Shew_1329
symbol: Shew_1329
gene_biotype: protein_coding
description:
  PFAM: N-acetylneuraminic acid synthase, N-terminal domain; SAF domain; KEGG: sdn:Sden_3113 N-acetylneuraminic acid synthase-like protein.


ensembl_gene_id: Shew_1331
symbol: Shew_1331
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_3115 spore coat polysaccharide biosynthesis protein predicted glycosyltransferase-like protein.


ensembl_gene_id: Shew_1332
symbol: Shew_1332
gene_biotype: protein_coding
description:
  Enoyl-[acyl-carrier-protein] reductase (NADH); PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sdn:Sden_3118 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_1333
symbol: Shew_1333
gene_biotype: protein_coding
description:
  PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: sdn:Sden_3119 3-oxoacyl-(acyl-carrier protein) synthase.


ensembl_gene_id: Shew_1334
symbol: Shew_1334
gene_biotype: protein_coding
description:
  PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: sdn:Sden_3120 3-oxoacyl-(acyl-carrier protein) synthase.


ensembl_gene_id: Shew_1339
symbol: Shew_1339
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF400; KEGG: shm:Shewmr7_1323 protein of unknown function DUF400.


ensembl_gene_id: Shew_1342
symbol: Shew_1342
gene_biotype: protein_coding
description:
  SAF domain protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: Shew_1343
symbol: Shew_1343
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; CheW domain protein; KEGG: she:Shewmr4_1257 response regulator receiver modulated CheW protein.


ensembl_gene_id: Shew_1344
symbol: Shew_1344
gene_biotype: protein_coding
description:
  PFAM: MCP methyltransferase, CheR-type; Methyltransferase type 12; KEGG: shm:Shewmr7_1328 MCP methyltransferase, CheR-type.


ensembl_gene_id: Shew_1345
symbol: Shew_1345
gene_biotype: protein_coding
description:
  Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: Shew_1346
symbol: Shew_1346
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: sfr:Sfri_1162 flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Shew_1347
symbol: Shew_1347
gene_biotype: protein_coding
description:
  Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.


ensembl_gene_id: Shew_1348
symbol: Shew_1348
gene_biotype: protein_coding
description:
  PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; KEGG: sfr:Sfri_1164 flagellar basal body FlaE domain protein.


ensembl_gene_id: Shew_1349
symbol: Shew_1349
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shm:Shewmr7_1333 flagellar basal-body rod protein FlgF; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Shew_1350
symbol: Shew_1350
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shm:Shewmr7_1334 flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Shew_1351
symbol: flgH
gene_biotype: protein_coding
description:
  Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Shew_1352
symbol: flgI
gene_biotype: protein_coding
description:
  Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: Shew_1353
symbol: Shew_1353
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1267 flagellar rod assembly protein/muramidase FlgJ; TIGRFAM: flagellar rod assembly protein/muramidase FlgJ; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2.


ensembl_gene_id: Shew_1354
symbol: Shew_1354
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shm:Shewmr7_1338 flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.


ensembl_gene_id: Shew_1355
symbol: Shew_1355
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: son:SO3239 flagellar hook-associated protein FlgL.


ensembl_gene_id: Shew_1356
symbol: Shew_1356
gene_biotype: protein_coding
description:
  Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: Shew_1359
symbol: Shew_1359
gene_biotype: protein_coding
description:
  Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: Shew_1362
symbol: Shew_1362
gene_biotype: protein_coding
description:
  Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_1278 sigma54 specific transcriptional regulator, fis family.


ensembl_gene_id: Shew_1363
symbol: Shew_1363
gene_biotype: protein_coding
description:
  PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein; KEGG: she:Shewmr4_1279 PAS/PAC sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_1364
symbol: Shew_1364
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_1180 two component, sigma54 specific, transcriptional regulator, fis family protein.


ensembl_gene_id: Shew_1365
symbol: fliE
gene_biotype: protein_coding
description:
  TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: shm:Shewmr7_1348 flagellar hook-basal body complex subunit FliE.


ensembl_gene_id: Shew_1366
symbol: Shew_1366
gene_biotype: protein_coding
description:
  Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: Shew_1367
symbol: Shew_1367
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: Shew_1369
symbol: Shew_1369
gene_biotype: protein_coding
description:
  Flagellar protein export ATPase FliI; KEGG: sdn:Sden_1327 ATPase FliI/YscN; TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase.


ensembl_gene_id: Shew_1371
symbol: Shew_1371
gene_biotype: protein_coding
description:
  PFAM: flagellar hook-length control protein; KEGG: sfr:Sfri_1187 flagellar hook-length control protein.


ensembl_gene_id: Shew_1372
symbol: Shew_1372
gene_biotype: protein_coding
description:
  Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: Shew_1373
symbol: Shew_1373
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: Shew_1374
symbol: Shew_1374
gene_biotype: protein_coding
description:
  Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: Shew_1375
symbol: Shew_1375
gene_biotype: protein_coding
description:
  PFAM: flagellar biosynthesis protein, FliO; KEGG: sfr:Sfri_1191 flagellar biosynthesis protein, FliO.


ensembl_gene_id: Shew_1376
symbol: fliP
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: Shew_1377
symbol: fliQ
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.


ensembl_gene_id: Shew_1378
symbol: Shew_1378
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.


ensembl_gene_id: Shew_1379
symbol: flhB
gene_biotype: protein_coding
description:
  Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: Shew_1380
symbol: flhA
gene_biotype: protein_coding
description:
  Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: Shew_1381
symbol: Shew_1381
gene_biotype: protein_coding
description:
  PFAM: GTP-binding signal recognition particle SRP54, G- domain; SMART: AAA ATPase; KEGG: son:SO3212 flagellar biosynthetic protein FlhF.


ensembl_gene_id: Shew_1382
symbol: Shew_1382
gene_biotype: protein_coding
description:
  PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_1365 cobyrinic acid a,c-diamide synthase.


ensembl_gene_id: Shew_1383
symbol: fliA
gene_biotype: protein_coding
description:
  RNA polymerase, sigma 28 subunit, FliA/WhiG family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: Shew_1385
symbol: cheZ
gene_biotype: protein_coding
description:
  Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: Shew_1386
symbol: Shew_1386
gene_biotype: protein_coding
description:
  CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: shm:Shewmr7_1369 CheA signal transduction histidine kinases.


ensembl_gene_id: Shew_1389
symbol: Shew_1389
gene_biotype: protein_coding
description:
  PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_1372 cobyrinic acid a,c-diamide synthase.


ensembl_gene_id: Shew_1397
symbol: Shew_1397
gene_biotype: protein_coding
description:
  TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1380 amino acid/peptide transporter.


ensembl_gene_id: Shew_1398
symbol: rfaH
gene_biotype: protein_coding
description:
  Transcription antitermination protein nusG; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family.


ensembl_gene_id: Shew_1401
symbol: Shew_1401
gene_biotype: protein_coding
description:
  TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: she:Shewmr4_1318 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: Shew_1402
symbol: Shew_1402
gene_biotype: protein_coding
description:
  Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: Shew_1403
symbol: Shew_1403
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.


ensembl_gene_id: Shew_1404
symbol: Shew_1404
gene_biotype: protein_coding
description:
  dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.


ensembl_gene_id: Shew_1407
symbol: Shew_1407
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: blo:BL0232 probable 3-oxoacyl-[acyl-carrier protein] reductase.


ensembl_gene_id: Shew_1408
symbol: Shew_1408
gene_biotype: protein_coding
description:
  2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; PFAM: thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: blo:BL0231 2-oxoglutarate decarboxylase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase.


ensembl_gene_id: Shew_1411
symbol: Shew_1411
gene_biotype: protein_coding
description:
  PFAM: transferase hexapeptide repeat containing protein; KEGG: pfl:PFL_5101 O-acetyltransferase, putative.


ensembl_gene_id: Shew_1414
symbol: Shew_1414
gene_biotype: protein_coding
description:
  PFAM: glycosyl transferase, family 2; KEGG: bfs:BF1562 putative glycosyltransferase O-antigen related protein.


ensembl_gene_id: Shew_1416
symbol: wecA
gene_biotype: protein_coding
description:
  Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). Belongs to the glycosyltransferase 4 family. WecA subfamily.


ensembl_gene_id: Shew_1418
symbol: Shew_1418
gene_biotype: protein_coding
description:
  UDP-glucose pyrophosphorylase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfr:Sfri_2823 UTP-glucose-1-phosphate uridylyltransferase.


ensembl_gene_id: Shew_1420
symbol: Shew_1420
gene_biotype: protein_coding
description:
  PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sfr:Sfri_3709 PHP C-terminal domain protein.


ensembl_gene_id: Shew_1422
symbol: cysD
gene_biotype: protein_coding
description:
  TIGRFAM: sulfate adenylyltransferase, small subunit; PFAM: phosphoadenosine phosphosulfate reductase; KEGG: sde:Sde_2145 sulfate adenylyltransferase, subunit 2.


ensembl_gene_id: Shew_1423
symbol: cysN
gene_biotype: protein_coding
description:
  Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: Shew_1424
symbol: Shew_1424
gene_biotype: protein_coding
description:
  PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: cps:CPS_2144 putative transporter.


ensembl_gene_id: Shew_1432
symbol: napF
gene_biotype: protein_coding
description:
  Ferredoxin-type protein NapF; Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family.


ensembl_gene_id: Shew_1433
symbol: Shew_1433
gene_biotype: protein_coding
description:
  TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: shm:Shewmr7_2676 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: Shew_1434
symbol: Shew_1434
gene_biotype: protein_coding
description:
  UDP-glucose pyrophosphorylase; KEGG: son:SO1665 UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.


ensembl_gene_id: Shew_1435
symbol: Shew_1435
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1328 phenylalanine-4-hydroxylase; TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase.


ensembl_gene_id: Shew_1436
symbol: Shew_1436
gene_biotype: protein_coding
description:
  PFAM: transcriptional coactivator/pterin dehydratase; KEGG: shm:Shewmr7_2673 transcriptional coactivator/pterin dehydratase.


ensembl_gene_id: Shew_1437
symbol: Shew_1437
gene_biotype: protein_coding
description:
  Transcriptional regulator, TyrR; PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: AAA ATPase; KEGG: son:SO1669 transcriptional regulatory protein TyrR.


ensembl_gene_id: Shew_1439
symbol: Shew_1439
gene_biotype: protein_coding
description:
  TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; KEGG: shm:Shewmr7_2670 maleylacetoacetate isomerase.


ensembl_gene_id: Shew_1440
symbol: Shew_1440
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1696 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_1442
symbol: Shew_1442
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO3138 C4-dicarboxylate transport transcriptional regulatory protein.


ensembl_gene_id: Shew_1443
symbol: Shew_1443
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_1360 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_1444
symbol: Shew_1444
gene_biotype: protein_coding
description:
  TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sfr:Sfri_2717 TRAP dicarboxylate transporter, DctM subunit.


ensembl_gene_id: Shew_1445
symbol: Shew_1445
gene_biotype: protein_coding
description:
  PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: shm:Shewmr7_1427 tripartite ATP-independent periplasmic transporter, DctQ component.


ensembl_gene_id: Shew_1446
symbol: dctP
gene_biotype: protein_coding
description:
  TRAP dicarboxylate transporter, DctP subunit; Part of the tripartite ATP-independent periplasmic (TRAP) transport system DctPQM involved in C4-dicarboxylates uptake (By similarity). Required for the utilization of succinate, fumarate, L- malate and alpha-ketoglutarate. Binds succinate and malate.


ensembl_gene_id: Shew_1447
symbol: Shew_1447
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: ftf:FTF0444 multidrug transporter (tetracycline resistance protein).


ensembl_gene_id: Shew_1449
symbol: gltX
gene_biotype: protein_coding
description:
  glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: Shew_1451
symbol: Shew_1451
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_1431 ABC transporter-related protein.


ensembl_gene_id: Shew_1452
symbol: Shew_1452
gene_biotype: protein_coding
description:
  DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: she:Shewmr4_1367 transcriptional regulator, AraC family.


ensembl_gene_id: Shew_1453
symbol: Shew_1453
gene_biotype: protein_coding
description:
  methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: Shew_1454
symbol: Shew_1454
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO3125 ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family.


ensembl_gene_id: Shew_1455
symbol: Shew_1455
gene_biotype: protein_coding
description:
  PFAM: Dual specificity protein phosphatase; KEGG: son:SO3124 tyrosine-specific protein phosphatase, putative.


ensembl_gene_id: Shew_1456
symbol: Shew_1456
gene_biotype: protein_coding
description:
  PFAM: phospholipase D/Transphosphatidylase; KEGG: shm:Shewmr7_1436 phospholipase D/transphosphatidylase.


ensembl_gene_id: Shew_1457
symbol: Shew_1457
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; CheW domain protein; KEGG: shm:Shewmr7_1437 response regulator receiver modulated CheW protein.


ensembl_gene_id: Shew_1458
symbol: sstT
gene_biotype: protein_coding
description:
  Sodium:dicarboxylate symporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Shew_1460
symbol: Shew_1460
gene_biotype: protein_coding
description:
  Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Shew_1463
symbol: Shew_1463
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO0766 transcriptional regulator, AraC/XylS family.


ensembl_gene_id: Shew_1464
symbol: nadE
gene_biotype: protein_coding
description:
  NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: Shew_1467
symbol: Shew_1467
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; KEGG: sdn:Sden_1435 GGDEF domain.


ensembl_gene_id: Shew_1471
symbol: Shew_1471
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414; Belongs to the UPF0352 family.


ensembl_gene_id: Shew_1472
symbol: Shew_1472
gene_biotype: protein_coding
description:
  PFAM: 37 kDa nucleoid-associated protein; KEGG: she:Shewmr4_2217 37 kDa nucleoid-associated protein.


ensembl_gene_id: Shew_1476
symbol: Shew_1476
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sdn:Sden_3374 sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Shew_1477
symbol: Shew_1477
gene_biotype: protein_coding
description:
  TIGRFAM: anti-sigma factor, putative, ChrR family; KEGG: sdn:Sden_3373 anti-sigma factor ChrR, putative.


ensembl_gene_id: Shew_1478
symbol: Shew_1478
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: cps:CPS_1379 hypothetical protein.


ensembl_gene_id: Shew_1479
symbol: Shew_1479
gene_biotype: protein_coding
description:
  Deoxyribodipyrimidine photo-lyase type I; PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein; KEGG: pha:PSHAb0453 putative deoxyribodipyrimidine photolyase.


ensembl_gene_id: Shew_1481
symbol: Shew_1481
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdn:Sden_3371 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Shew_1484
symbol: Shew_1484
gene_biotype: protein_coding
description:
  PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sdn:Sden_3368 cyclopropane-fatty-acyl-phospholipid synthase.


ensembl_gene_id: Shew_1488
symbol: Shew_1488
gene_biotype: protein_coding
description:
  PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein; KEGG: vpa:VPA0635 putative oxidoreductase, oxygen dependent, FAD-dependent protein.


ensembl_gene_id: Shew_1491
symbol: Shew_1491
gene_biotype: protein_coding
description:
  PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: she:Shewmr4_2209 ion transport protein.


ensembl_gene_id: Shew_1492
symbol: Shew_1492
gene_biotype: protein_coding
description:
  TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; KEGG: son:SO1918 MATE efflux family protein.


ensembl_gene_id: Shew_1494
symbol: Shew_1494
gene_biotype: protein_coding
description:
  PFAM: uncharacterized conserved protein UCP029143; KEGG: vvu:VV20047 hypothetical protein; Belongs to the UPF0267 family.


ensembl_gene_id: Shew_1500
symbol: Shew_1500
gene_biotype: protein_coding
description:
  PFAM: CBS domain containing protein; KEGG: sfr:Sfri_2274 putative signal-transduction protein with CBS domains.


ensembl_gene_id: Shew_1502
symbol: Shew_1502
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF748; KEGG: she:Shewmr4_2416 protein of unknown function DUF748.


ensembl_gene_id: Shew_1503
symbol: Shew_1503
gene_biotype: protein_coding
description:
  PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mxa:MXAN_6919 ferredoxin reductase.


ensembl_gene_id: Shew_1506
symbol: Shew_1506
gene_biotype: protein_coding
description:
  PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_1598 glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Shew_1507
symbol: Shew_1507
gene_biotype: protein_coding
description:
  PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: vch:VC2669 5-carboxymethyl-2-hydroxymuconate delta isomerase, putative.


ensembl_gene_id: Shew_1508
symbol: Shew_1508
gene_biotype: protein_coding
description:
  SMART: extracellular solute-binding protein, family 3; KEGG: dvu:DVUA0150 bacterial extracellular solute-binding protein, family 3.


ensembl_gene_id: Shew_1509
symbol: Shew_1509
gene_biotype: protein_coding
description:
  TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: shm:Shewmr7_2456 asparagine synthase (glutamine-hydrolyzing).


ensembl_gene_id: Shew_1511
symbol: Shew_1511
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_2382 HAD-superfamily hydrolase, subfamily IIA.


ensembl_gene_id: Shew_1512
symbol: purN
gene_biotype: protein_coding
description:
  Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: Shew_1513
symbol: purM
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1452 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein.


ensembl_gene_id: Shew_1514
symbol: upp
gene_biotype: protein_coding
description:
  Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: Shew_1515
symbol: Shew_1515
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaC; PFAM: Gluconate transporter; Citrate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_2377 Na+/H+ antiporter NhaC.


ensembl_gene_id: Shew_1516
symbol: Shew_1516
gene_biotype: protein_coding
description:
  PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_2448 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.


ensembl_gene_id: Shew_1517
symbol: Shew_1517
gene_biotype: protein_coding
description:
  TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: son:SO3778 adenylate cyclase CyaB, putative.


ensembl_gene_id: Shew_1520
symbol: rnt
gene_biotype: protein_coding
description:
  RNAse T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: Shew_1522
symbol: Shew_1522
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: shm:Shewmr7_2445 prolyl oligopeptidase.


ensembl_gene_id: Shew_1523
symbol: Shew_1523
gene_biotype: protein_coding
description:
  TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2444 4-hydroxybenzoyl-CoA thioesterase.


ensembl_gene_id: Shew_1524
symbol: tolQ
gene_biotype: protein_coding
description:
  MotA/TolQ/ExbB proton channel; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Shew_1525
symbol: tolR
gene_biotype: protein_coding
description:
  Biopolymer transport protein ExbD/TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Shew_1527
symbol: tolB
gene_biotype: protein_coding
description:
  TolB, N-terminal domain protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Shew_1528
symbol: pal
gene_biotype: protein_coding
description:
  OmpA domain protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: Shew_1529
symbol: cpoB
gene_biotype: protein_coding
description:
  Tetratricopeptide TPR_2 repeat protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: Shew_1531
symbol: Shew_1531
gene_biotype: protein_coding
description:
  TIGRFAM: Glutaredoxin, GrxA family; PFAM: glutaredoxin; KEGG: shm:Shewmr7_2436 glutaredoxin, GrxA family.


ensembl_gene_id: Shew_1532
symbol: Shew_1532
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2435 type III restriction enzyme, res subunit.


ensembl_gene_id: Shew_1533
symbol: acsA
gene_biotype: protein_coding
description:
  Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: Shew_1534
symbol: Shew_1534
gene_biotype: protein_coding
description:
  Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_2361 multi-sensor hybrid histidine kinase.


ensembl_gene_id: Shew_1539
symbol: Shew_1539
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1785 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_1540
symbol: Shew_1540
gene_biotype: protein_coding
description:
  PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shm:Shewmr7_2191 alcohol dehydrogenase, zinc-binding domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: Shew_1544
symbol: Shew_1544
gene_biotype: protein_coding
description:
  Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; KEGG: ppr:PBPRB0492 hypothetical protein.


ensembl_gene_id: Shew_1545
symbol: Shew_1545
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_1663 two component transcriptional regulator, LuxR family.


ensembl_gene_id: Shew_1546
symbol: Shew_1546
gene_biotype: protein_coding
description:
  PFAM: thioesterase superfamily protein; KEGG: son:SO2647 cytosolic long-chain acyl-CoA thioester hydrolase family protein.


ensembl_gene_id: Shew_1548
symbol: Shew_1548
gene_biotype: protein_coding
description:
  Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: Shew_1549
symbol: Shew_1549
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: Shew_1555
symbol: Shew_1555
gene_biotype: protein_coding
description:
  PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: sdn:Sden_1823 Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.


ensembl_gene_id: Shew_1557
symbol: Shew_1557
gene_biotype: protein_coding
description:
  PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: sfr:Sfri_2263 cupin 4 family protein.


ensembl_gene_id: Shew_1558
symbol: Shew_1558
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_2262 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.


ensembl_gene_id: Shew_1559
symbol: hflD
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF489; KEGG: she:Shewmr4_1602 protein of unknown function DUF489.


ensembl_gene_id: Shew_1560
symbol: mnmA
gene_biotype: protein_coding
description:
  tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.


ensembl_gene_id: Shew_1561
symbol: nudJ
gene_biotype: protein_coding
description:
  PFAM: NUDIX hydrolase; KEGG: son:SO2631 MutT/nudix family protein; Belongs to the Nudix hydrolase family. NudJ subfamily.


ensembl_gene_id: Shew_1562
symbol: Shew_1562
gene_biotype: protein_coding
description:
  PFAM: pseudouridine synthase; KEGG: sfr:Sfri_2258 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Shew_1563
symbol: Shew_1563
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1681 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family.


ensembl_gene_id: Shew_1564
symbol: Shew_1564
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1721 cold-shock DNA-binding domain protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein.


ensembl_gene_id: Shew_1565
symbol: clpS
gene_biotype: protein_coding
description:
  ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: Shew_1566
symbol: Shew_1566
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.


ensembl_gene_id: Shew_1567
symbol: infA
gene_biotype: protein_coding
description:
  Bacterial translation initiation factor 1 (bIF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: Shew_1568
symbol: bpt
gene_biotype: protein_coding
description:
  Arginyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily.


ensembl_gene_id: Shew_1569
symbol: aat
gene_biotype: protein_coding
description:
  Leucyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: Shew_1573
symbol: metG
gene_biotype: protein_coding
description:
  methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: Shew_1574
symbol: Shew_1574
gene_biotype: protein_coding
description:
  ATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: Shew_1575
symbol: udk
gene_biotype: protein_coding
description:
  TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: shm:Shewmr7_1732 uridine kinase.


ensembl_gene_id: Shew_1577
symbol: Shew_1577
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase apoprotein; PFAM: aminotransferase, class IV; KEGG: shm:Shewmr7_1734 aminotransferase, class IV.


ensembl_gene_id: Shew_1578
symbol: mltG
gene_biotype: protein_coding
description:
  Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: Shew_1579
symbol: tmk
gene_biotype: protein_coding
description:
  Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: Shew_1580
symbol: Shew_1580
gene_biotype: protein_coding
description:
  TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: son:SO2612 DNA polymerase III, delta prime subunit.


ensembl_gene_id: Shew_1582
symbol: Shew_1582
gene_biotype: protein_coding
description:
  TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_1739 hydrolase, TatD family.


ensembl_gene_id: Shew_1583
symbol: rsmF
gene_biotype: protein_coding
description:
  Putative RNA methylase, NOL1/NOP2/sun family; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.


ensembl_gene_id: Shew_1584
symbol: Shew_1584
gene_biotype: protein_coding
description:
  PFAM: nucleoside recognition domain protein; KEGG: she:Shewmr4_1666 nucleoside recognition domain protein.


ensembl_gene_id: Shew_1586
symbol: Shew_1586
gene_biotype: protein_coding
description:
  Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: Shew_1588
symbol: Shew_1588
gene_biotype: protein_coding
description:
  PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: she:Shewmr4_2189 protein tyrosine phosphatase.


ensembl_gene_id: Shew_1589
symbol: Shew_1589
gene_biotype: protein_coding
description:
  GTP-binding protein, HSR1-related; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.


ensembl_gene_id: Shew_1590
symbol: Shew_1590
gene_biotype: protein_coding
description:
  PFAM: 2OG-Fe(II) oxygenase; KEGG: shm:Shewmr7_2262 2OG-Fe(II) oxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family.


ensembl_gene_id: Shew_1591
symbol: msrA
gene_biotype: protein_coding
description:
  Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: Shew_1592
symbol: Shew_1592
gene_biotype: protein_coding
description:
  PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sdn:Sden_2303 sulphate transporter.


ensembl_gene_id: Shew_1593
symbol: rne
gene_biotype: protein_coding
description:
  RNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: Shew_1594
symbol: Shew_1594
gene_biotype: protein_coding
description:
  Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: Shew_1595
symbol: Shew_1595
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sfr:Sfri_1492 HAD-superfamily hydrolase, subfamily IA, variant 1.


ensembl_gene_id: Shew_1596
symbol: Shew_1596
gene_biotype: protein_coding
description:
  TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: mca:MCA0985 sensory box protein.


ensembl_gene_id: Shew_1597
symbol: Shew_1597
gene_biotype: protein_coding
description:
  Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: Shew_1599
symbol: rpmF
gene_biotype: protein_coding
description:
  TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: sdn:Sden_2297 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.


ensembl_gene_id: Shew_1600
symbol: plsX
gene_biotype: protein_coding
description:
  Phosphate:acyl-[acyl carrier protein] acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: Shew_1601
symbol: fabH
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: Shew_1602
symbol: Shew_1602
gene_biotype: protein_coding
description:
  TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: she:Shewmr4_2397 malonyl CoA-acyl carrier protein transacylase.


ensembl_gene_id: Shew_1603
symbol: Shew_1603
gene_biotype: protein_coding
description:
  3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Shew_1605
symbol: Shew_1605
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: Shew_1607
symbol: Shew_1607
gene_biotype: protein_coding
description:
  PFAM: thioesterase superfamily protein; KEGG: son:SO2772 cytosolic long-chain acyl-CoA thioester hydrolase family protein.


ensembl_gene_id: Shew_1609
symbol: Shew_1609
gene_biotype: protein_coding
description:
  PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: she:Shewmr4_2391 6-phosphogluconate dehydrogenase, NAD-binding.


ensembl_gene_id: Shew_1610
symbol: cdd
gene_biotype: protein_coding
description:
  Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: Shew_1611
symbol: Shew_1611
gene_biotype: protein_coding
description:
  PFAM: Exonuclease, RNase T and DNA polymerase III; Exonuclease C-terminal domain protein; KEGG: son:SO2790 exodeoxyribonuclease I.


ensembl_gene_id: Shew_1613
symbol: Shew_1613
gene_biotype: protein_coding
description:
  rRNA (guanine-N(1)-)-methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO2788 ribosomal RNA large subunit methyltransferase A.


ensembl_gene_id: Shew_1614
symbol: Shew_1614
gene_biotype: protein_coding
description:
  PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shm:Shewmr7_2477 cold-shock DNA-binding domain protein.


ensembl_gene_id: Shew_1615
symbol: Shew_1615
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_1627 ABC transporter-related protein.


ensembl_gene_id: Shew_1617
symbol: Shew_1617
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF480; KEGG: she:Shewmr4_1554 protein of unknown function DUF480; Belongs to the UPF0502 family.


ensembl_gene_id: Shew_1621
symbol: Shew_1621
gene_biotype: protein_coding
description:
  Agmatinase; TIGRFAM: putative agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: sdn:Sden_2278 agmatinase, putative; Belongs to the arginase family.


ensembl_gene_id: Shew_1622
symbol: pdxH
gene_biotype: protein_coding
description:
  Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: Shew_1624
symbol: Shew_1624
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2649 transcriptional regulator for cysteine regulon.


ensembl_gene_id: Shew_1625
symbol: Shew_1625
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1804 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family.


ensembl_gene_id: Shew_1626
symbol: nagZ
gene_biotype: protein_coding
description:
  Glycoside hydrolase, family 3 domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: Shew_1627
symbol: Shew_1627
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0227; KEGG: shm:Shewmr7_1806 protein of unknown function UPF0227; Belongs to the UPF0227 family.


ensembl_gene_id: Shew_1630
symbol: mfd
gene_biotype: protein_coding
description:
  Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: Shew_1632
symbol: Shew_1632
gene_biotype: protein_coding
description:
  TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_1812 lipoprotein releasing system, transmembrane protein, LolC/E family.


ensembl_gene_id: Shew_1633
symbol: lolD
gene_biotype: protein_coding
description:
  Lipoprotein releasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.


ensembl_gene_id: Shew_1634
symbol: Shew_1634
gene_biotype: protein_coding
description:
  TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: son:SO2259 lipoprotein releasing system transmembrane protein LolC, putative.


ensembl_gene_id: Shew_1635
symbol: Shew_1635
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE domain protein; KEGG: vch:VCA0960 GGDEF family protein.


ensembl_gene_id: Shew_1637
symbol: Shew_1637
gene_biotype: protein_coding
description:
  TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: she:Shewmr4_2423 DNA internalization-related competence protein ComEC/Rec2.


ensembl_gene_id: Shew_1638
symbol: msbA
gene_biotype: protein_coding
description:
  Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: Shew_1639
symbol: lpxK
gene_biotype: protein_coding
description:
  lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: Shew_1640
symbol: Shew_1640
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF343; KEGG: shm:Shewmr7_2490 protein of unknown function DUF343; Belongs to the UPF0434 family.


ensembl_gene_id: Shew_1645
symbol: Shew_1645
gene_biotype: protein_coding
description:
  Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: shm:Shewmr7_3505 sigma54 specific transcriptional regulator, fis family.


ensembl_gene_id: Shew_1647
symbol: Shew_1647
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1627 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_1648
symbol: Shew_1648
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1628 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_1649
symbol: Shew_1649
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; secretion protein HlyD family protein; KEGG: she:Shewmr4_1629 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_1650
symbol: Shew_1650
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1705 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: Shew_1651
symbol: Shew_1651
gene_biotype: protein_coding
description:
  PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: shm:Shewmr7_1706 succinate dehydrogenase, cytochrome b subunit.


ensembl_gene_id: Shew_1653
symbol: Shew_1653
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1708 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Shew_1654
symbol: Shew_1654
gene_biotype: protein_coding
description:
  TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: she:Shewmr4_1634 succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: Shew_1655
symbol: Shew_1655
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1635 2-oxoglutarate dehydrogenase, E1 subunit; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; Transketolase, central region.


ensembl_gene_id: Shew_1656
symbol: Shew_1656
gene_biotype: protein_coding
description:
  2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: Shew_1657
symbol: sucC
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: Shew_1658
symbol: sucD
gene_biotype: protein_coding
description:
  succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: Shew_1659
symbol: Shew_1659
gene_biotype: protein_coding
description:
  PFAM: ferredoxin-dependent glutamate synthase; KEGG: cps:CPS_3206 glutamate synthase domain protein; Belongs to the glutamate synthase family.


ensembl_gene_id: Shew_1661
symbol: fur
gene_biotype: protein_coding
description:
  Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: shm:Shewmr7_1716 ferric uptake regulator, Fur family; Belongs to the Fur family.


ensembl_gene_id: Shew_1662
symbol: cobB
gene_biotype: protein_coding
description:
  PFAM: Silent information regulator protein Sir2; KEGG: she:Shewmr4_1642 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.


ensembl_gene_id: Shew_1665
symbol: Shew_1665
gene_biotype: protein_coding
description:
  PFAM: peptidase S51, dipeptidase E; KEGG: sbo:SBO_4042 peptidase E; Belongs to the peptidase S51 family.


ensembl_gene_id: Shew_1667
symbol: Shew_1667
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_1943 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; Belongs to the thiolase-like superfamily. Thiolase family.


ensembl_gene_id: Shew_1668
symbol: Shew_1668
gene_biotype: protein_coding
description:
  TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2596 methylmalonate-semialdehyde dehydrogenase.


ensembl_gene_id: Shew_1669
symbol: Shew_1669
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: shm:Shewmr7_2662 acyl-CoA dehydrogenase domain protein.


ensembl_gene_id: Shew_1670
symbol: Shew_1670
gene_biotype: protein_coding
description:
  PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2661 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Shew_1672
symbol: Shew_1672
gene_biotype: protein_coding
description:
  KEGG: son:SO1682 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; Belongs to the HIBADH-related family.


ensembl_gene_id: Shew_1673
symbol: Shew_1673
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_2658 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Shew_1675
symbol: Shew_1675
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: shm:Shewmr7_2656 peptidase S9, prolyl oligopeptidase active site domain protein.


ensembl_gene_id: Shew_1676
symbol: Shew_1676
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2586 ABC transporter-related protein.


ensembl_gene_id: Shew_1677
symbol: Shew_1677
gene_biotype: protein_coding
description:
  PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: cps:CPS_4956 cytosol aminopeptidase family protein.


ensembl_gene_id: Shew_1681
symbol: Shew_1681
gene_biotype: protein_coding
description:
  KEGG: tcx:Tcr_0379 diguanylate cyclase (GGDEF domain) with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein.


ensembl_gene_id: Shew_1685
symbol: Shew_1685
gene_biotype: protein_coding
description:
  Microbial collagenase; PFAM: peptidase domain protein; Peptidase M9A, collagenase C-terminal domain protein; Peptidase M9, N-terminal domain; KEGG: son:SO0639 collagenase family.


ensembl_gene_id: Shew_1688
symbol: Shew_1688
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_0392 TonB-dependent receptor, plug.


ensembl_gene_id: Shew_1696
symbol: Shew_1696
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_2629 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Shew_1697
symbol: Shew_1697
gene_biotype: protein_coding
description:
  PFAM: amino acid-binding ACT domain protein; KEGG: she:Shewmr4_2561 amino acid-binding ACT domain protein.


ensembl_gene_id: Shew_1698
symbol: Shew_1698
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_2560 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Shew_1699
symbol: Shew_1699
gene_biotype: protein_coding
description:
  TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2626 phosphate ABC transporter, inner membrane subunit PstA.


ensembl_gene_id: Shew_1700
symbol: pstB
gene_biotype: protein_coding
description:
  Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: Shew_1713
symbol: Shew_1713
gene_biotype: protein_coding
description:
  PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; KEGG: son:SO1742 putative 3-oxoacyl-[acyl-carrier-protein] synthase III.


ensembl_gene_id: Shew_1716
symbol: Shew_1716
gene_biotype: protein_coding
description:
  3-beta hydroxysteroid dehydrogenase/isomerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: ppr:PBPRA1465 steroid dehydrogenase.


ensembl_gene_id: Shew_1718
symbol: Shew_1718
gene_biotype: protein_coding
description:
  Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: shm:Shewmr7_2432 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: Shew_1719
symbol: bioB
gene_biotype: protein_coding
description:
  Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: Shew_1720
symbol: Shew_1720
gene_biotype: protein_coding
description:
  8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: son:SO2739 8-amino-7-oxononanoate synthase.


ensembl_gene_id: Shew_1721
symbol: Shew_1721
gene_biotype: protein_coding
description:
  PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_2357 biotin biosynthesis protein BioC.


ensembl_gene_id: Shew_1722
symbol: bioD
gene_biotype: protein_coding
description:
  Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.


ensembl_gene_id: Shew_1723
symbol: htpX
gene_biotype: protein_coding
description:
  HtpX-2 peptidase. Metallo peptidase. MEROPS family M48B; PFAM: peptidase M48, Ste24p; HtpX domain protein; KEGG: shm:Shewmr7_2423 HtpX domain protein; Belongs to the peptidase M48B family.


ensembl_gene_id: Shew_1729
symbol: Shew_1729
gene_biotype: protein_coding
description:
  PFAM: Curli production assembly/transport component CsgG; KEGG: sfr:Sfri_1520 curli production assembly/transport component CsgG.


ensembl_gene_id: Shew_1732
symbol: Shew_1732
gene_biotype: protein_coding
description:
  TIGRFAM: uncharacterized domain 1 protein; PFAM: thioesterase superfamily protein; KEGG: son:SO2722 hypothetical protein.


ensembl_gene_id: Shew_1735
symbol: Shew_1735
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2310 TonB-dependent receptor.


ensembl_gene_id: Shew_1737
symbol: Shew_1737
gene_biotype: protein_coding
description:
  TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: son:SO2713 transporter, putative.


ensembl_gene_id: Shew_1738
symbol: Shew_1738
gene_biotype: protein_coding
description:
  PFAM: Choline/ethanolamine kinase; aminoglycoside phosphotransferase; KEGG: sdn:Sden_2318 aminoglycoside phosphotransferase.


ensembl_gene_id: Shew_1755
symbol: hypA
gene_biotype: protein_coding
description:
  Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: Shew_1756
symbol: Shew_1756
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sfr:Sfri_2112 hydrogenase expression/formation protein HypE.


ensembl_gene_id: Shew_1757
symbol: Shew_1757
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: shm:Shewmr7_2163 hydrogenase expression/formation protein HypD; Belongs to the HypD family.


ensembl_gene_id: Shew_1758
symbol: Shew_1758
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: son:SO2092 hydrogenase assembly chaperone hypC/hupF.


ensembl_gene_id: Shew_1759
symbol: Shew_1759
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: she:Shewmr4_1816 hydrogenase accessory protein HypB.


ensembl_gene_id: Shew_1760
symbol: Shew_1760
gene_biotype: protein_coding
description:
  (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.


ensembl_gene_id: Shew_1762
symbol: Shew_1762
gene_biotype: protein_coding
description:
  TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52, hydrogen uptake protein; KEGG: shm:Shewmr7_2158 hydrogenase expression/formation protein.


ensembl_gene_id: Shew_1763
symbol: Shew_1763
gene_biotype: protein_coding
description:
  TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: she:Shewmr4_1820 Ni/Fe-hydrogenase, b-type cytochrome subunit.


ensembl_gene_id: Shew_1764
symbol: Shew_1764
gene_biotype: protein_coding
description:
  PFAM: nickel-dependent hydrogenase, large subunit; KEGG: she:Shewmr4_1821 nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.


ensembl_gene_id: Shew_1765
symbol: Shew_1765
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2155 hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein.


ensembl_gene_id: Shew_1766
symbol: Shew_1766
gene_biotype: protein_coding
description:
  PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_2139 putative signal transduction protein with CBS domains.


ensembl_gene_id: Shew_1767
symbol: Shew_1767
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2138 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like.


ensembl_gene_id: Shew_1768
symbol: Shew_1768
gene_biotype: protein_coding
description:
  PFAM: periplasmic nitrate reductase NapE; KEGG: shm:Shewmr7_2137 periplasmic nitrate reductase NapE.


ensembl_gene_id: Shew_1769
symbol: napD
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase chaperone NapD; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: Shew_1770
symbol: napA
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase subunit NapA apoprotein; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.


ensembl_gene_id: Shew_1771
symbol: Shew_1771
gene_biotype: protein_coding
description:
  Periplasmic nitrate reductase subunit NapB; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: Shew_1772
symbol: Shew_1772
gene_biotype: protein_coding
description:
  TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: shm:Shewmr7_2133 periplasmic nitrate (or nitrite) reductase C-type cytochrome, NapC/NirT family.


ensembl_gene_id: Shew_1773
symbol: Shew_1773
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vfi:VFA0105 transcriptional regulator.


ensembl_gene_id: Shew_1775
symbol: Shew_1775
gene_biotype: protein_coding
description:
  TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sdn:Sden_2123 acetolactate synthase, small subunit.


ensembl_gene_id: Shew_1776
symbol: Shew_1776
gene_biotype: protein_coding
description:
  TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: son:SO2279 acetolactate synthase large subunit.


ensembl_gene_id: Shew_1777
symbol: Shew_1777
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1831 drug resistance transporter, Bcr/CflA subfamily.


ensembl_gene_id: Shew_1781
symbol: Shew_1781
gene_biotype: protein_coding
description:
  PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_1760 rhodanese domain protein; Belongs to the UPF0176 family.


ensembl_gene_id: Shew_1783
symbol: Shew_1783
gene_biotype: protein_coding
description:
  PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_0517 secretion protein HlyD family protein.


ensembl_gene_id: Shew_1789
symbol: Shew_1789
gene_biotype: protein_coding
description:
  TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: she:Shewmr4_2204 cystathionine beta-lyase.


ensembl_gene_id: Shew_1790
symbol: Shew_1790
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_2203 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_1791
symbol: Shew_1791
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfr:Sfri_1623 two component transcriptional regulator, winged helix family protein.


ensembl_gene_id: Shew_1793
symbol: Shew_1793
gene_biotype: protein_coding
description:
  PFAM: von Willebrand factor, type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa; KEGG: shm:Shewmr7_2277 vault protein inter-alpha-trypsin domain protein.


ensembl_gene_id: Shew_1794
symbol: Shew_1794
gene_biotype: protein_coding
description:
  TIGRFAM: sortase family protein; PFAM: peptidase C60, sortase A and B; KEGG: she:Shewmr4_2199 sortase family protein.


ensembl_gene_id: Shew_1795
symbol: Shew_1795
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_2198 diguanylate cyclase.


ensembl_gene_id: Shew_1796
symbol: Shew_1796
gene_biotype: protein_coding
description:
  PFAM: Mammalian cell entry related domain protein; KEGG: she:Shewmr4_1667 mammalian cell entry related domain protein.


ensembl_gene_id: Shew_1801
symbol: proQ
gene_biotype: protein_coding
description:
  ProQ activator of osmoprotectant transporter ProP; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family.


ensembl_gene_id: Shew_1802
symbol: Shew_1802
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1748 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; Belongs to the peptidase S41A family.


ensembl_gene_id: Shew_1803
symbol: Shew_1803
gene_biotype: protein_coding
description:
  TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_1749 aminopeptidase N.


ensembl_gene_id: Shew_1805
symbol: Shew_1805
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1302; KEGG: shm:Shewmr7_1751 protein of unknown function DUF1302.


ensembl_gene_id: Shew_1806
symbol: Shew_1806
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1329; KEGG: shm:Shewmr7_1752 protein of unknown function DUF1329.


ensembl_gene_id: Shew_1810
symbol: pyrD
gene_biotype: protein_coding
description:
  Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: Shew_1811
symbol: zapC
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1379; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: Shew_1812
symbol: rlmL
gene_biotype: protein_coding
description:
  Putative RNA methylase; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: Shew_1814
symbol: Shew_1814
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_1542 ABC transporter-related protein.


ensembl_gene_id: Shew_1816
symbol: rmf
gene_biotype: protein_coding
description:
  Ribosome modulation factor; During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.


ensembl_gene_id: Shew_1817
symbol: fabA
gene_biotype: protein_coding
description:
  3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: Shew_1819
symbol: Shew_1819
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sdn:Sden_1663 GntR-like protein.


ensembl_gene_id: Shew_1820
symbol: prpB
gene_biotype: protein_coding
description:
  2,3-dimethylmalate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.


ensembl_gene_id: Shew_1821
symbol: Shew_1821
gene_biotype: protein_coding
description:
  KEGG: pat:Patl_1420 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.


ensembl_gene_id: Shew_1823
symbol: Shew_1823
gene_biotype: protein_coding
description:
  Methylitaconate delta2-delta3-isomerase; TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: pen:PSEEN1906 hypothetical protein.


ensembl_gene_id: Shew_1824
symbol: Shew_1824
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: shm:Shewmr7_1614 two component transcriptional regulator, LuxR family.


ensembl_gene_id: Shew_1825
symbol: uvrC
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: Shew_1826
symbol: Shew_1826
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1616 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: Shew_1828
symbol: Shew_1828
gene_biotype: protein_coding
description:
  PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sfr:Sfri_1440 peptidoglycan-binding domain 1 protein.


ensembl_gene_id: Shew_1829
symbol: Shew_1829
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: shm:Shewmr7_2145 protein of unknown function DUF882.


ensembl_gene_id: Shew_1830
symbol: rplY
gene_biotype: protein_coding
description:
  LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: Shew_1832
symbol: Shew_1832
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF444; KEGG: shm:Shewmr7_1645 protein of unknown function DUF444; Belongs to the UPF0229 family.


ensembl_gene_id: Shew_1834
symbol: Shew_1834
gene_biotype: protein_coding
description:
  Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: Shew_1835
symbol: Shew_1835
gene_biotype: protein_coding
description:
  TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: shm:Shewmr7_1648 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily.


ensembl_gene_id: Shew_1836
symbol: Shew_1836
gene_biotype: protein_coding
description:
  TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: shm:Shewmr7_1649 uracil-xanthine permease.


ensembl_gene_id: Shew_1838
symbol: Shew_1838
gene_biotype: protein_coding
description:
  Regulatory inactivation of DnaA Hda protein; PFAM: Chromosomal replication initiator, DnaA; KEGG: shm:Shewmr7_1651 chromosomal replication initiator, DnaA; Belongs to the DnaA family. HdA subfamily.


ensembl_gene_id: Shew_1840
symbol: Shew_1840
gene_biotype: protein_coding
description:
  TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sfr:Sfri_1754 arsenate reductase.


ensembl_gene_id: Shew_1841
symbol: Shew_1841
gene_biotype: protein_coding
description:
  Peptidase M48, Ste24p; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: Shew_1842
symbol: Shew_1842
gene_biotype: protein_coding
description:
  PFAM: SirA family protein; KEGG: she:Shewmr4_2346 SirA family protein; Belongs to the sulfur carrier protein TusA family.


ensembl_gene_id: Shew_1843
symbol: Shew_1843
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_2417 protein of unknown function UPF0118.


ensembl_gene_id: Shew_1844
symbol: Shew_1844
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2866 chromosome initiation inhibitor; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: Shew_1845
symbol: Shew_1845
gene_biotype: protein_coding
description:
  PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_2415 lysine exporter protein (LysE/YggA).


ensembl_gene_id: Shew_1846
symbol: Shew_1846
gene_biotype: protein_coding
description:
  Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pat:Patl_2480 redoxin.


ensembl_gene_id: Shew_1847
symbol: Shew_1847
gene_biotype: protein_coding
description:
  PFAM: amino acid-binding ACT domain protein; KEGG: shm:Shewmr7_2413 amino acid-binding ACT domain protein.


ensembl_gene_id: Shew_1848
symbol: dapA
gene_biotype: protein_coding
description:
  Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: Shew_1849
symbol: bamC
gene_biotype: protein_coding
description:
  NlpBDapX family lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: Shew_1850
symbol: Shew_1850
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: pha:PSHAa1182 hypothetical protein; GGDEF protein.


ensembl_gene_id: Shew_1851
symbol: Shew_1851
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_2410 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_1852
symbol: Shew_1852
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_2409 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_1856
symbol: kdsB
gene_biotype: protein_coding
description:
  3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family.


ensembl_gene_id: Shew_1857
symbol: Shew_1857
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; KEGG: sdn:Sden_2133 iron-containing alcohol dehydrogenase.


ensembl_gene_id: Shew_1858
symbol: Shew_1858
gene_biotype: protein_coding
description:
  PFAM: aminotransferase, class V; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: shm:Shewmr7_2125 DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: Shew_1859
symbol: Shew_1859
gene_biotype: protein_coding
description:
  Carbonate dehydratase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: Shew_1861
symbol: Shew_1861
gene_biotype: protein_coding
description:
  PFAM: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; KEGG: sfr:Sfri_1764 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins.


ensembl_gene_id: Shew_1862
symbol: dapE1
gene_biotype: protein_coding
description:
  Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: Shew_1863
symbol: Shew_1863
gene_biotype: protein_coding
description:
  PFAM: arsenate reductase and related; KEGG: she:Shewmr4_1858 hypothetical protein; Belongs to the ArsC family.


ensembl_gene_id: Shew_1864
symbol: Shew_1864
gene_biotype: protein_coding
description:
  KEGG: sfr:Sfri_1767 PTS system, glucose subfamily, IIA subunit; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PFAM: sugar-specific permease, EIIA 1 domain.


ensembl_gene_id: Shew_1865
symbol: Shew_1865
gene_biotype: protein_coding
description:
  Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: Shew_1866
symbol: Shew_1866
gene_biotype: protein_coding
description:
  TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: shm:Shewmr7_1843 phosphocarrier, HPr family.


ensembl_gene_id: Shew_1868
symbol: Shew_1868
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_1845 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_1870
symbol: Shew_1870
gene_biotype: protein_coding
description:
  Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_1847 transcriptional regulator, LacI family.


ensembl_gene_id: Shew_1871
symbol: Shew_1871
gene_biotype: protein_coding
description:
  KEGG: vfi:VFA0016 DNA polymerase III epsilon subunit (3'-5' exonuclease); TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.


ensembl_gene_id: Shew_1873
symbol: Shew_1873
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2109 glucan 1,4-alpha-glucosidase; TIGRFAM: glucan 1,4-alpha-glucosidase; PFAM: glycoside hydrolase 15-related.


ensembl_gene_id: Shew_1874
symbol: Shew_1874
gene_biotype: protein_coding
description:
  PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1870 major facilitator superfamily MFS_1.


ensembl_gene_id: Shew_1875
symbol: Shew_1875
gene_biotype: protein_coding
description:
  PFAM: peptidase M20; Fibronectin, type III domain protein; peptidase M28; KEGG: sfr:Sfri_3859 peptidase M28.


ensembl_gene_id: Shew_1882
symbol: Shew_1882
gene_biotype: protein_coding
description:
  PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sfr:Sfri_2300 metal dependent phosphohydrolase.


ensembl_gene_id: Shew_1884
symbol: Shew_1884
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: vpa:VP0903 RhlE; Belongs to the DEAD box helicase family.


ensembl_gene_id: Shew_1886
symbol: Shew_1886
gene_biotype: protein_coding
description:
  PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: sfr:Sfri_1784 alpha amylase, catalytic region.


ensembl_gene_id: Shew_1887
symbol: Shew_1887
gene_biotype: protein_coding
description:
  PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: shm:Shewmr7_2211 alpha amylase, catalytic region; Belongs to the glycosyl hydrolase 13 family.


ensembl_gene_id: Shew_1888
symbol: Shew_1888
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2134 TonB-dependent receptor.


ensembl_gene_id: Shew_1889
symbol: Shew_1889
gene_biotype: protein_coding
description:
  PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: son:SO2213 alpha-glucosidase.


ensembl_gene_id: Shew_1890
symbol: Shew_1890
gene_biotype: protein_coding
description:
  TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_1789 glucose/galactose transporter.


ensembl_gene_id: Shew_1891
symbol: Shew_1891
gene_biotype: protein_coding
description:
  PFAM: Fmu (Sun) domain protein; KEGG: son:SO2215 sun protein, putative; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.


ensembl_gene_id: Shew_1892
symbol: Shew_1892
gene_biotype: protein_coding
description:
  PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pae:PA0799 probable helicase.


ensembl_gene_id: Shew_1893
symbol: Shew_1893
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0047; KEGG: sde:Sde_0527 alpha-1,6-glucosidases, pullulanase-type.


ensembl_gene_id: Shew_1894
symbol: Shew_1894
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.


ensembl_gene_id: Shew_1898
symbol: Shew_1898
gene_biotype: protein_coding
description:
  ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: Shew_1900
symbol: asnS
gene_biotype: protein_coding
description:
  TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase, class II (D, K and N); nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: she:Shewmr4_2128 asparaginyl-tRNA synthetase.


ensembl_gene_id: Shew_1903
symbol: Shew_1903
gene_biotype: protein_coding
description:
  TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: shm:Shewmr7_2201 para-aminobenzoate synthase, subunit I.


ensembl_gene_id: Shew_1904
symbol: Shew_1904
gene_biotype: protein_coding
description:
  Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.


ensembl_gene_id: Shew_1905
symbol: Shew_1905
gene_biotype: protein_coding
description:
  PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: son:SO2223 peptidase, putative.


ensembl_gene_id: Shew_1909
symbol: Shew_1909
gene_biotype: protein_coding
description:
  PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: pat:Patl_3690 2OG-Fe(II) oxygenase.


ensembl_gene_id: Shew_1910
symbol: Shew_1910
gene_biotype: protein_coding
description:
  PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: she:Shewmr4_1683 iron-containing alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: Shew_1911
symbol: Shew_1911
gene_biotype: protein_coding
description:
  PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: shm:Shewmr7_1759 multiple antibiotic resistance (MarC)-related proteins.


ensembl_gene_id: Shew_1912
symbol: Shew_1912
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1933 putative deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; Belongs to the dGTPase family. Type 2 subfamily.


ensembl_gene_id: Shew_1913
symbol: Shew_1913
gene_biotype: protein_coding
description:
  Metal dependent phosphohydrolase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: Shew_1915
symbol: efp
gene_biotype: protein_coding
description:
  Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.


ensembl_gene_id: Shew_1917
symbol: Shew_1917
gene_biotype: protein_coding
description:
  Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: Shew_1920
symbol: Shew_1920
gene_biotype: protein_coding
description:
  PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_1942 alpha/beta hydrolase fold.


ensembl_gene_id: Shew_1921
symbol: seqA
gene_biotype: protein_coding
description:
  SeqA family protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: Shew_1922
symbol: Shew_1922
gene_biotype: protein_coding
description:
  TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sfr:Sfri_1915 phosphoglucomutase, alpha-D-glucose phosphate-specific.


ensembl_gene_id: Shew_1924
symbol: astE
gene_biotype: protein_coding
description:
  Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: Shew_1925
symbol: Shew_1925
gene_biotype: protein_coding
description:
  PFAM: dehydrogenase, E1 component; KEGG: shm:Shewmr7_1947 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring).


ensembl_gene_id: Shew_1926
symbol: Shew_1926
gene_biotype: protein_coding
description:
  PFAM: Transketolase, central region; Transketolase domain protein; KEGG: shm:Shewmr7_1948 transketolase, central region.


ensembl_gene_id: Shew_1927
symbol: Shew_1927
gene_biotype: protein_coding
description:
  PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes.


ensembl_gene_id: Shew_1928
symbol: nadA
gene_biotype: protein_coding
description:
  Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: Shew_1929
symbol: Shew_1929
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Nitrate and nitrite sensing domain protein; KEGG: shm:Shewmr7_1760 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_1931
symbol: Shew_1931
gene_biotype: protein_coding
description:
  TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein-like; KEGG: sdn:Sden_1233 alkylphosphonate utilization operon protein PhnA.


ensembl_gene_id: Shew_1932
symbol: clsA
gene_biotype: protein_coding
description:
  Cardiolipin synthetase 2; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: Shew_1936
symbol: Shew_1936
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_2074 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_1940
symbol: Shew_1940
gene_biotype: protein_coding
description:
  TIGRFAM: L-asparaginases, type I; PFAM: Asparaginase/glutaminase; KEGG: she:Shewmr4_1908 L-asparaginases, type I.


ensembl_gene_id: Shew_1941
symbol: Shew_1941
gene_biotype: protein_coding
description:
  TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: son:SO2420 signal peptide peptidase SppA, 67K type.


ensembl_gene_id: Shew_1942
symbol: Shew_1942
gene_biotype: protein_coding
description:
  PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfr:Sfri_2144 NADH:flavin oxidoreductase/NADH oxidase.


ensembl_gene_id: Shew_1945
symbol: Shew_1945
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase class Ia beta subunit; PFAM: ribonucleotide reductase; KEGG: shm:Shewmr7_2063 ribonucleoside-diphosphate reductase.


ensembl_gene_id: Shew_1946
symbol: Shew_1946
gene_biotype: protein_coding
description:
  Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: Shew_1947
symbol: Shew_1947
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1917 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase.


ensembl_gene_id: Shew_1948
symbol: ubiG
gene_biotype: protein_coding
description:
  3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: Shew_1949
symbol: gyrA
gene_biotype: protein_coding
description:
  DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: Shew_1950
symbol: serC
gene_biotype: protein_coding
description:
  Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: Shew_1952
symbol: aroA
gene_biotype: protein_coding
description:
  3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: Shew_1953
symbol: cmk
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2055 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.


ensembl_gene_id: Shew_1954
symbol: Shew_1954
gene_biotype: protein_coding
description:
  SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: Shew_1955
symbol: ihfB
gene_biotype: protein_coding
description:
  Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Shew_1956
symbol: lapA
gene_biotype: protein_coding
description:
  Protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: Shew_1957
symbol: lapB
gene_biotype: protein_coding
description:
  Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: Shew_1958
symbol: pyrF
gene_biotype: protein_coding
description:
  Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: Shew_1959
symbol: Shew_1959
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdn:Sden_1758 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_1961
symbol: Shew_1961
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: she:Shewmr4_1931 acyl-CoA dehydrogenase domain protein.


ensembl_gene_id: Shew_1962
symbol: Shew_1962
gene_biotype: protein_coding
description:
  KEGG: son:SO2394 penicillin-binding protein 4; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C.


ensembl_gene_id: Shew_1965
symbol: Shew_1965
gene_biotype: protein_coding
description:
  PFAM: phospholipase D/Transphosphatidylase; KEGG: she:Shewmr4_1935 phospholipase D/transphosphatidylase.


ensembl_gene_id: Shew_1969
symbol: Shew_1969
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: son:SO1416 DNA-binding response regulator.


ensembl_gene_id: Shew_1970
symbol: Shew_1970
gene_biotype: protein_coding
description:
  Histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO1417 sensor histidine kinase.


ensembl_gene_id: Shew_1975
symbol: Shew_1975
gene_biotype: protein_coding
description:
  Inorganic diphosphatase; PFAM: phosphoesterase, RecJ domain protein; DHHA2 domain protein; KEGG: son:SO4190 inorganic pyrophosphatase, manganese-dependent.


ensembl_gene_id: Shew_1977
symbol: Shew_1977
gene_biotype: protein_coding
description:
  Diguanylate cyclase with PAS/PAC sensor; KEGG: cps:CPS_3923 sensory box/GGDEF domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.


ensembl_gene_id: Shew_1981
symbol: Shew_1981
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: pfl:PFL_2378 transcriptional regulator, AraC family.


ensembl_gene_id: Shew_1982
symbol: Shew_1982
gene_biotype: protein_coding
description:
  PFAM: phage integrase family protein; KEGG: shm:Shewmr7_1973 phage integrase family protein; Belongs to the 'phage' integrase family.


ensembl_gene_id: Shew_1983
symbol: Shew_1983
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_1971 response regulator receiver modulated metal dependent phosphohydrolase.


ensembl_gene_id: Shew_1985
symbol: Shew_1985
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome c oxidase, cbb3-type, subunit I; PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_1969 cytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family.


ensembl_gene_id: Shew_1986
symbol: Shew_1986
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; PFAM: cytochrome C oxidase, mono-heme subunit/FixO; KEGG: son:SO2363 cytochrome c oxidase, cbb3-type, subunit II.


ensembl_gene_id: Shew_1987
symbol: Shew_1987
gene_biotype: protein_coding
description:
  PFAM: Cbb3-type cytochrome oxidase component; KEGG: sdn:Sden_1849 Cbb3-type cytochrome oxidase component.


ensembl_gene_id: Shew_1988
symbol: Shew_1988
gene_biotype: protein_coding
description:
  Cytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.


ensembl_gene_id: Shew_1990
symbol: Shew_1990
gene_biotype: protein_coding
description:
  Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: son:SO2359 cation transport ATPase, E1-E2 family.


ensembl_gene_id: Shew_1991
symbol: Shew_1991
gene_biotype: protein_coding
description:
  TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: sdn:Sden_1845 cytochrome oxidase maturation protein, cbb3-type.


ensembl_gene_id: Shew_1993
symbol: Shew_1993
gene_biotype: protein_coding
description:
  Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: shm:Shewmr7_1961 transcriptional regulator, Crp/Fnr family.


ensembl_gene_id: Shew_1995
symbol: ttcA
gene_biotype: protein_coding
description:
  PP-loop domain protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: Shew_1998
symbol: Shew_1998
gene_biotype: protein_coding
description:
  Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: Shew_2000
symbol: Shew_2000
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_1793 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Shew_2002
symbol: Shew_2002
gene_biotype: protein_coding
description:
  KEGG: son:SO2345 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.


ensembl_gene_id: Shew_2008
symbol: Shew_2008
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KEGG: vfi:VF1658 short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: Shew_2010
symbol: Shew_2010
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sdn:Sden_1711 secretion protein HlyD; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_2011
symbol: Shew_2011
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: sfr:Sfri_1929 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_2012
symbol: Shew_2012
gene_biotype: protein_coding
description:
  TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1975 drug resistance transporter, Bcr/CflA subfamily.


ensembl_gene_id: Shew_2013
symbol: Shew_2013
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1974 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2014
symbol: Shew_2014
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0005; KEGG: shm:Shewmr7_2003 protein of unknown function UPF0005; Belongs to the BI1 family.


ensembl_gene_id: Shew_2016
symbol: Shew_2016
gene_biotype: protein_coding
description:
  PFAM: DsrE family protein; KEGG: shm:Shewmr7_2005 DsrE family protein; Belongs to the DsrF/TusC family.


ensembl_gene_id: Shew_2020
symbol: serS
gene_biotype: protein_coding
description:
  seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: Shew_2021
symbol: crcB
gene_biotype: protein_coding
description:
  Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: Shew_2022
symbol: Shew_2022
gene_biotype: protein_coding
description:
  PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2011 AAA ATPase, central domain protein.


ensembl_gene_id: Shew_2023
symbol: lolA
gene_biotype: protein_coding
description:
  Outer membrane lipoprotein carrier protein LolA; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: Shew_2024
symbol: Shew_2024
gene_biotype: protein_coding
description:
  DNA translocase FtsK; PFAM: cell divisionFtsK/SpoIIIE; KEGG: she:Shewmr4_1963 cell divisionFtsK/SpoIIIE.


ensembl_gene_id: Shew_2025
symbol: Shew_2025
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, AsnC/Lrp family; KEGG: shm:Shewmr7_2014 transcriptional regulator, AsnC family.


ensembl_gene_id: Shew_2026
symbol: Shew_2026
gene_biotype: protein_coding
description:
  TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: shm:Shewmr7_2015 alanine dehydrogenase; Belongs to the AlaDH/PNT family.


ensembl_gene_id: Shew_2027
symbol: Shew_2027
gene_biotype: protein_coding
description:
  Alanine dehydrogenase/PNT domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: sfr:Sfri_1793 alanine dehydrogenase.


ensembl_gene_id: Shew_2028
symbol: Shew_2028
gene_biotype: protein_coding
description:
  TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1959 thioredoxin reductase.


ensembl_gene_id: Shew_2029
symbol: rplT
gene_biotype: protein_coding
description:
  LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: Shew_2030
symbol: rpmI
gene_biotype: protein_coding
description:
  PFAM: ribosomal protein L35; KEGG: sfr:Sfri_2026 ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.


ensembl_gene_id: Shew_2031
symbol: infC
gene_biotype: protein_coding
description:
  Bacterial translation initiation factor 3 (bIF-3); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: Shew_2032
symbol: thrS
gene_biotype: protein_coding
description:
  threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).


ensembl_gene_id: Shew_2036
symbol: Shew_2036
gene_biotype: protein_coding
description:
  TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: she:Shewmr4_1952 riboflavin synthase, alpha subunit.


ensembl_gene_id: Shew_2037
symbol: Shew_2037
gene_biotype: protein_coding
description:
  TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shm:Shewmr7_2025 MATE efflux family protein.


ensembl_gene_id: Shew_2039
symbol: Shew_2039
gene_biotype: protein_coding
description:
  PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: she:Shewmr4_2098 CoA-binding domain protein.


ensembl_gene_id: Shew_2040
symbol: Shew_2040
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_1872 diguanylate cyclase.


ensembl_gene_id: Shew_2042
symbol: Shew_2042
gene_biotype: protein_coding
description:
  PFAM: regulatory protein, MarR; KEGG: ppr:PBPRA1008 putative transcriptional regulator, MarR family.


ensembl_gene_id: Shew_2043
symbol: Shew_2043
gene_biotype: protein_coding
description:
  TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_1868 cation diffusion facilitator family transporter.


ensembl_gene_id: Shew_2045
symbol: Shew_2045
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_2043 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase.


ensembl_gene_id: Shew_2046
symbol: edd
gene_biotype: protein_coding
description:
  6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: Shew_2048
symbol: zwf
gene_biotype: protein_coding
description:
  Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.


ensembl_gene_id: Shew_2049
symbol: Shew_2049
gene_biotype: protein_coding
description:
  Transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: son:SO2490 transcriptional regulator, RpiR family.


ensembl_gene_id: Shew_2051
symbol: Shew_2051
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; KEGG: son:SO2492 oxidoreductase, acyl-CoA dehydrogenase family.


ensembl_gene_id: Shew_2057
symbol: Shew_2057
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: she:Shewmr4_2055 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s).


ensembl_gene_id: Shew_2060
symbol: Shew_2060
gene_biotype: protein_coding
description:
  PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: sdn:Sden_2013 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.


ensembl_gene_id: Shew_2061
symbol: queE
gene_biotype: protein_coding
description:
  Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: Shew_2062
symbol: queC
gene_biotype: protein_coding
description:
  exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: Shew_2064
symbol: uvrB
gene_biotype: protein_coding
description:
  Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate  [...]


ensembl_gene_id: Shew_2065
symbol: Shew_2065
gene_biotype: protein_coding
description:
  Diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_2063 diguanylate cyclase/phosphodiesterase.


ensembl_gene_id: Shew_2066
symbol: rnfA
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, A subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: Shew_2067
symbol: rnfB
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: Shew_2068
symbol: rnfC
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, C subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: Shew_2069
symbol: rnfD
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, D subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: Shew_2070
symbol: rnfG
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, G subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: Shew_2071
symbol: rnfE
gene_biotype: protein_coding
description:
  Electron transport complex, RnfABCDGE type, E subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: Shew_2072
symbol: nth
gene_biotype: protein_coding
description:
  Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: Shew_2073
symbol: Shew_2073
gene_biotype: protein_coding
description:
  KEGG: son:SO2044 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Shew_2074
symbol: Shew_2074
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2416 TonB-dependent receptor.


ensembl_gene_id: Shew_2075
symbol: ruvB
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: Shew_2076
symbol: ruvA
gene_biotype: protein_coding
description:
  Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: Shew_2077
symbol: ruvC
gene_biotype: protein_coding
description:
  Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: Shew_2079
symbol: aspS
gene_biotype: protein_coding
description:
  aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: Shew_2080
symbol: Shew_2080
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; extracellular solute-binding protein, family 3; KEGG: shm:Shewmr7_2081 diguanylate cyclase.


ensembl_gene_id: Shew_2081
symbol: cmoA
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: Shew_2082
symbol: cmoB
gene_biotype: protein_coding
description:
  Putative methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: Shew_2083
symbol: Shew_2083
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF785; KEGG: she:Shewmr4_1894 protein of unknown function DUF785.


ensembl_gene_id: Shew_2085
symbol: Shew_2085
gene_biotype: protein_coding
description:
  TIGRFAM: alpha-L-glutamate ligase-like protein; KEGG: she:Shewmr4_1892 alpha-L-glutamate ligase-like protein.


ensembl_gene_id: Shew_2088
symbol: Shew_2088
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2089 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2091
symbol: Shew_2091
gene_biotype: protein_coding
description:
  TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; KEGG: she:Shewmr4_1886 thiazole biosynthesis protein ThiH.


ensembl_gene_id: Shew_2092
symbol: thiG
gene_biotype: protein_coding
description:
  Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: Shew_2093
symbol: Shew_2093
gene_biotype: protein_coding
description:
  TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sdn:Sden_1773 thiamine biosynthesis protein ThiS.


ensembl_gene_id: Shew_2094
symbol: Shew_2094
gene_biotype: protein_coding
description:
  PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: son:SO2443 thiF protein, putative.


ensembl_gene_id: Shew_2095
symbol: Shew_2095
gene_biotype: protein_coding
description:
  Phosphomethylpyrimidine kinase; KEGG: shm:Shewmr7_2096 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; phosphomethylpyrimidine kinase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1.


ensembl_gene_id: Shew_2096
symbol: thiC
gene_biotype: protein_coding
description:
  Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: Shew_2098
symbol: Shew_2098
gene_biotype: protein_coding
description:
  TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: she:Shewmr4_1879 channel protein, hemolysin III family.


ensembl_gene_id: Shew_2100
symbol: dnaE2
gene_biotype: protein_coding
description:
  DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.


ensembl_gene_id: Shew_2103
symbol: def
gene_biotype: protein_coding
description:
  Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: Shew_2105
symbol: Shew_2105
gene_biotype: protein_coding
description:
  PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: shm:Shewmr7_2220 methylated-DNA-(protein)-cysteine S-methyltransferase.


ensembl_gene_id: Shew_2107
symbol: Shew_2107
gene_biotype: protein_coding
description:
  PFAM: glutamine amidotransferase, class-II; KEGG: she:Shewmr4_2145 glutamine amidotransferase, class-II.


ensembl_gene_id: Shew_2108
symbol: Shew_2108
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; KEGG: shm:Shewmr7_2223 acyl-CoA dehydrogenase domain protein.


ensembl_gene_id: Shew_2109
symbol: Shew_2109
gene_biotype: protein_coding
description:
  PFAM: sodium/hydrogen exchanger; KEGG: shm:Shewmr7_2224 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: Shew_2111
symbol: dnaQ
gene_biotype: protein_coding
description:
  DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: Shew_2114
symbol: gloB
gene_biotype: protein_coding
description:
  Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: Shew_2115
symbol: Shew_2115
gene_biotype: protein_coding
description:
  PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: she:Shewmr4_2162 MLTD_N domain protein.


ensembl_gene_id: Shew_2117
symbol: Shew_2117
gene_biotype: protein_coding
description:
  Regulator of ribonuclease activity A; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.


ensembl_gene_id: Shew_2119
symbol: Shew_2119
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: sfr:Sfri_2212 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_2121
symbol: Shew_2121
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; KEGG: sfr:Sfri_3387 diguanylate cyclase.


ensembl_gene_id: Shew_2122
symbol: msrQ
gene_biotype: protein_coding
description:
  Ferric reductase domain protein transmembrane component, N-terminal domain; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduct [...]


ensembl_gene_id: Shew_2123
symbol: msrP
gene_biotype: protein_coding
description:
  Oxidoreductase, molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce  [...]


ensembl_gene_id: Shew_2124
symbol: Shew_2124
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF195; KEGG: shm:Shewmr7_1864 protein of unknown function DUF195.


ensembl_gene_id: Shew_2126
symbol: Shew_2126
gene_biotype: protein_coding
description:
  PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shm:Shewmr7_1856 ATPase associated with various cellular activities, AAA_3.


ensembl_gene_id: Shew_2129
symbol: recC
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: Shew_2130
symbol: recB
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, beta subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...]


ensembl_gene_id: Shew_2131
symbol: recD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]


ensembl_gene_id: Shew_2134
symbol: Shew_2134
gene_biotype: protein_coding
description:
  PFAM: heat shock protein Hsp20; KEGG: son:SO2277 16 kDa heat shock protein A; Belongs to the small heat shock protein (HSP20) family.


ensembl_gene_id: Shew_2135
symbol: Shew_2135
gene_biotype: protein_coding
description:
  5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sfr:Sfri_2309 5'-nucleotidase; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: Shew_2137
symbol: Shew_2137
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase, C-terminal domain; KEGG: ppr:PBPRA2730 putative glutathione S-transferase.


ensembl_gene_id: Shew_2141
symbol: Shew_2141
gene_biotype: protein_coding
description:
  TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_2269 lytic murein transglycosylase.


ensembl_gene_id: Shew_2145
symbol: Shew_2145
gene_biotype: protein_coding
description:
  PFAM: MscS Mechanosensitive ion channel; KEGG: vvy:VVA1412 small-conductance mechanosensitive channel.


ensembl_gene_id: Shew_2153
symbol: Shew_2153
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1965 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2155
symbol: Shew_2155
gene_biotype: protein_coding
description:
  KEGG: sdn:Sden_2163 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.


ensembl_gene_id: Shew_2158
symbol: Shew_2158
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_2297 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.


ensembl_gene_id: Shew_2159
symbol: Shew_2159
gene_biotype: protein_coding
description:
  TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: shm:Shewmr7_1220 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor.


ensembl_gene_id: Shew_2160
symbol: Shew_2160
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_2301 dipeptidase, putative; TIGRFAM: dipeptidase, putative; PFAM: peptidase M20; peptidase dimerisation domain protein.


ensembl_gene_id: Shew_2161
symbol: Shew_2161
gene_biotype: protein_coding
description:
  Peptidyl-dipeptidase Dcp; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: she:Shewmr4_2302 peptidyl-dipeptidase DCP.


ensembl_gene_id: Shew_2162
symbol: Shew_2162
gene_biotype: protein_coding
description:
  TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: shm:Shewmr7_1591 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family.


ensembl_gene_id: Shew_2163
symbol: Shew_2163
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF938; Methyltransferase type 11; KEGG: sfr:Sfri_2306 protein of unknown function DUF938.


ensembl_gene_id: Shew_2164
symbol: Shew_2164
gene_biotype: protein_coding
description:
  PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sfr:Sfri_2744 acyl-CoA dehydrogenase domain protein.


ensembl_gene_id: Shew_2165
symbol: Shew_2165
gene_biotype: protein_coding
description:
  PFAM: Aldose 1-epimerase; KEGG: shm:Shewmr7_2460 aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family.


ensembl_gene_id: Shew_2168
symbol: Shew_2168
gene_biotype: protein_coding
description:
  PFAM: uncharacterized conserved protein UCP025560; KEGG: shm:Shewmr7_2188 uncharacterized conserved protein UCP025560.


ensembl_gene_id: Shew_2170
symbol: Shew_2170
gene_biotype: protein_coding
description:
  Endonuclease/exonuclease/phosphatase; PFAM: PKD domain containing protein; Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_1534 PKD domain containing protein.


ensembl_gene_id: Shew_2175
symbol: nhaB
gene_biotype: protein_coding
description:
  Na+/H+ antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: Shew_2176
symbol: dsbB
gene_biotype: protein_coding
description:
  Disulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: Shew_2181
symbol: Shew_2181
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0153; KEGG: sdn:Sden_1632 uncharacterized conserved protein UCP006173; Belongs to the UPF0260 family.


ensembl_gene_id: Shew_2184
symbol: minC
gene_biotype: protein_coding
description:
  Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: Shew_2185
symbol: Shew_2185
gene_biotype: protein_coding
description:
  TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_2251 septum site-determining protein MinD.


ensembl_gene_id: Shew_2186
symbol: minE
gene_biotype: protein_coding
description:
  Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: Shew_2187
symbol: rnd
gene_biotype: protein_coding
description:
  Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: Shew_2194
symbol: Shew_2194
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_2651 protein of unknown function DUF6, transmembrane.


ensembl_gene_id: Shew_2195
symbol: Shew_2195
gene_biotype: protein_coding
description:
  NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pha:PSHAb0118 respiratory NADH dehydrogenase II.


ensembl_gene_id: Shew_2197
symbol: hisG
gene_biotype: protein_coding
description:
  ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.


ensembl_gene_id: Shew_2198
symbol: hisD
gene_biotype: protein_coding
description:
  Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: Shew_2199
symbol: hisC
gene_biotype: protein_coding
description:
  TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: sfr:Sfri_1718 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: Shew_2200
symbol: hisB
gene_biotype: protein_coding
description:
  Histidinol-phosphate phosphatase / imidazoleglycerol-phosphate dehydratase; KEGG: sfr:Sfri_1717 histidinol-phosphatase; TIGRFAM: histidinol-phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: imidazoleglycerol-phosphate dehydratase; In the N-terminal section; belongs to the histidinol- phosphatase family.


ensembl_gene_id: Shew_2201
symbol: hisH
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: Shew_2202
symbol: hisA
gene_biotype: protein_coding
description:
  1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; KEGG: she:Shewmr4_1795 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.


ensembl_gene_id: Shew_2203
symbol: hisF
gene_biotype: protein_coding
description:
  Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: Shew_2204
symbol: hisI
gene_biotype: protein_coding
description:
  PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: son:SO2067 phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family.


ensembl_gene_id: Shew_2205
symbol: Shew_2205
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sde:Sde_0667 response regulator receiver domain protein (CheY-like).


ensembl_gene_id: Shew_2206
symbol: Shew_2206
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hch:HCH_01757 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.


ensembl_gene_id: Shew_2207
symbol: Shew_2207
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: TPR repeat-containing protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pha:PSHAa0111 hypothetical protein.


ensembl_gene_id: Shew_2208
symbol: Shew_2208
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: sdn:Sden_3290 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family.


ensembl_gene_id: Shew_2209
symbol: Shew_2209
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; PKD domain containing protein; Proprotein convertase, P; KEGG: sdn:Sden_3093 peptidase S8 and S53, subtilisin, kexin, sedolisin; Belongs to the peptidase S8 family.


ensembl_gene_id: Shew_2210
symbol: Shew_2210
gene_biotype: protein_coding
description:
  PFAM: Proprotein convertase, P; KEGG: pha:PSHAb0200 putative secreted serine protease, subtilisin family, possibly excreted.


ensembl_gene_id: Shew_2211
symbol: purC
gene_biotype: protein_coding
description:
  PFAM: SAICAR synthetase; KEGG: sde:Sde_0669 phosphoribosylaminoimidazole-succinocarboxamide synthase.


ensembl_gene_id: Shew_2212
symbol: Shew_2212
gene_biotype: protein_coding
description:
  Peptidyl-dipeptidase Dcp; PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: she:Shewmr4_1525 peptidyl-dipeptidase DCP.


ensembl_gene_id: Shew_2213
symbol: lpxM
gene_biotype: protein_coding
description:
  Lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: Shew_2214
symbol: ihfA
gene_biotype: protein_coding
description:
  Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: Shew_2215
symbol: pheT
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1809 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.


ensembl_gene_id: Shew_2216
symbol: pheS
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1808 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc; aminoacyl tRNA synthetase, class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: Shew_2217
symbol: Shew_2217
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2170 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_2218
symbol: Shew_2218
gene_biotype: protein_coding
description:
  Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; KEGG: son:SO2889 sensory box histidine kinase.


ensembl_gene_id: Shew_2219
symbol: Shew_2219
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF785; KEGG: she:Shewmr4_1564 protein of unknown function DUF785.


ensembl_gene_id: Shew_2224
symbol: topA
gene_biotype: protein_coding
description:
  DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: Shew_2225
symbol: astB
gene_biotype: protein_coding
description:
  Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: Shew_2227
symbol: Shew_2227
gene_biotype: protein_coding
description:
  PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_1657 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: Shew_2230
symbol: adk
gene_biotype: protein_coding
description:
  Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: Shew_2233
symbol: recR
gene_biotype: protein_coding
description:
  Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: Shew_2234
symbol: Shew_2234
gene_biotype: protein_coding
description:
  Conserved hypothetical protein 103; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: Shew_2235
symbol: Shew_2235
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_2326 DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase.


ensembl_gene_id: Shew_2236
symbol: apt
gene_biotype: protein_coding
description:
  Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: Shew_2237
symbol: Shew_2237
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF454; KEGG: shm:Shewmr7_2328 protein of unknown function DUF454.


ensembl_gene_id: Shew_2240
symbol: Shew_2240
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: sfr:Sfri_2412 protein of unknown function DUF692; Belongs to the UPF0276 family.


ensembl_gene_id: Shew_2242
symbol: dusC
gene_biotype: protein_coding
description:
  Dihydrouridine synthase, DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: Shew_2244
symbol: Shew_2244
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_2335 TonB-dependent receptor.


ensembl_gene_id: Shew_2246
symbol: Shew_2246
gene_biotype: protein_coding
description:
  PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_1533 pseudouridine synthase, Rsu; Belongs to the pseudouridine synthase RsuA family.


ensembl_gene_id: Shew_2247
symbol: Shew_2247
gene_biotype: protein_coding
description:
  Condensin subunit ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: Shew_2248
symbol: Shew_2248
gene_biotype: protein_coding
description:
  Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.


ensembl_gene_id: Shew_2249
symbol: Shew_2249
gene_biotype: protein_coding
description:
  Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: shm:Shewmr7_1530 SUA5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.


ensembl_gene_id: Shew_2250
symbol: Shew_2250
gene_biotype: protein_coding
description:
  PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sdn:Sden_2449 PHP-like protein.


ensembl_gene_id: Shew_2251
symbol: Shew_2251
gene_biotype: protein_coding
description:
  TIGRFAM: anthranilate synthase component I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: sfr:Sfri_1429 anthranilate synthase component I.


ensembl_gene_id: Shew_2252
symbol: Shew_2252
gene_biotype: protein_coding
description:
  Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: sfr:Sfri_1428 glutamine amidotransferase of anthranilate synthase.


ensembl_gene_id: Shew_2253
symbol: trpD
gene_biotype: protein_coding
description:
  Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: Shew_2254
symbol: trpC
gene_biotype: protein_coding
description:
  PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); Indole-3-glycerol phosphate synthase; KEGG: son:SO3022 indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family.


ensembl_gene_id: Shew_2255
symbol: trpB
gene_biotype: protein_coding
description:
  Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: Shew_2256
symbol: trpA
gene_biotype: protein_coding
description:
  Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: Shew_2257
symbol: Shew_2257
gene_biotype: protein_coding
description:
  TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdn:Sden_0759 HAD-superfamily hydrolase, subfamily IA, variant 1.


ensembl_gene_id: Shew_2258
symbol: Shew_2258
gene_biotype: protein_coding
description:
  PFAM: NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30; KEGG: sfr:Sfri_3246 hypothetical protein.


ensembl_gene_id: Shew_2259
symbol: Shew_2259
gene_biotype: protein_coding
description:
  PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sfr:Sfri_1823 metal dependent phosphohydrolase.


ensembl_gene_id: Shew_2260
symbol: Shew_2260
gene_biotype: protein_coding
description:
  Intracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: Shew_2262
symbol: Shew_2262
gene_biotype: protein_coding
description:
  TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: shm:Shewmr7_1513 exodeoxyribonuclease III.


ensembl_gene_id: Shew_2263
symbol: Shew_2263
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_1507 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_2265
symbol: Shew_2265
gene_biotype: protein_coding
description:
  PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: shm:Shewmr7_1505 twin-arginine translocation pathway signal.


ensembl_gene_id: Shew_2266
symbol: Shew_2266
gene_biotype: protein_coding
description:
  PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sfr:Sfri_1414 (2Fe-2S)-binding domain protein.


ensembl_gene_id: Shew_2275
symbol: Shew_2275
gene_biotype: protein_coding
description:
  PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: sfr:Sfri_1824 extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.


ensembl_gene_id: Shew_2278
symbol: Shew_2278
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: par:Psyc_1132 probable transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2281
symbol: Shew_2281
gene_biotype: protein_coding
description:
  TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: son:SO3058 flavocytochrome c flavin subunit, putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.


ensembl_gene_id: Shew_2282
symbol: Shew_2282
gene_biotype: protein_coding
description:
  Transcriptional regulator, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: son:SO3059 formate hydrogenlyase transcriptional activator, putative.


ensembl_gene_id: Shew_2285
symbol: Shew_2285
gene_biotype: protein_coding
description:
  TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: vpa:VPA0879 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.


ensembl_gene_id: Shew_2286
symbol: Shew_2286
gene_biotype: protein_coding
description:
  TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pha:PSHAa1768 sodium/hexose cotransport protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Shew_2287
symbol: galK
gene_biotype: protein_coding
description:
  Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: Shew_2288
symbol: Shew_2288
gene_biotype: protein_coding
description:
  UDP-glucose-hexose-1-phosphate uridylyltransferase / UTP-hexose-1-phosphate uridylyltransferase; KEGG: pha:PSHAa1770 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein.


ensembl_gene_id: Shew_2289
symbol: Shew_2289
gene_biotype: protein_coding
description:
  PFAM: Glycosyl hydrolase family 98, putative carbohydrate binding module; KEGG: dge:Dgeo_2665 glycosyl hydrolase family 98, putative carbohydrate binding module.


ensembl_gene_id: Shew_2292
symbol: Shew_2292
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0340 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2295
symbol: Shew_2295
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: msu:MS1229 AraC protein.


ensembl_gene_id: Shew_2296
symbol: Shew_2296
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_2604 TonB-dependent receptor.


ensembl_gene_id: Shew_2299
symbol: topB
gene_biotype: protein_coding
description:
  DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]


ensembl_gene_id: Shew_2301
symbol: Shew_2301
gene_biotype: protein_coding
description:
  PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2991 methyl-accepting chemotaxis sensory transducer.


ensembl_gene_id: Shew_2302
symbol: purF
gene_biotype: protein_coding
description:
  Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: Shew_2305
symbol: Shew_2305
gene_biotype: protein_coding
description:
  TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: sfr:Sfri_1396 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.


ensembl_gene_id: Shew_2306
symbol: truA
gene_biotype: protein_coding
description:
  tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: Shew_2308
symbol: asd
gene_biotype: protein_coding
description:
  Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: Shew_2309
symbol: pdxB
gene_biotype: protein_coding
description:
  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: Shew_2310
symbol: ndk
gene_biotype: protein_coding
description:
  Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: Shew_2311
symbol: Shew_2311
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF528; KEGG: shm:Shewmr7_1826 protein of unknown function DUF528.


ensembl_gene_id: Shew_2312
symbol: Shew_2312
gene_biotype: protein_coding
description:
  TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: shm:Shewmr7_1824 ferredoxin, 2Fe-2S type, ISC system.


ensembl_gene_id: Shew_2313
symbol: hscA
gene_biotype: protein_coding
description:
  Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.


ensembl_gene_id: Shew_2314
symbol: hscB
gene_biotype: protein_coding
description:
  Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: Shew_2315
symbol: Shew_2315
gene_biotype: protein_coding
description:
  Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.


ensembl_gene_id: Shew_2316
symbol: Shew_2316
gene_biotype: protein_coding
description:
  FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: Shew_2317
symbol: iscS
gene_biotype: protein_coding
description:
  Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.


ensembl_gene_id: Shew_2318
symbol: Shew_2318
gene_biotype: protein_coding
description:
  Transcriptional regulator, BadM/Rrf2 family; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: Shew_2320
symbol: trmJ
gene_biotype: protein_coding
description:
  RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: Shew_2323
symbol: Shew_2323
gene_biotype: protein_coding
description:
  PFAM: phosphate-starvation-inducible E; KEGG: shm:Shewmr7_2496 phosphate-starvation-inducible E; Belongs to the PsiE family.


ensembl_gene_id: Shew_2328
symbol: Shew_2328
gene_biotype: protein_coding
description:
  Signal transduction histidine kinase, LytS; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; KEGG: shm:Shewmr7_2501 signal transduction histidine kinase, LytS.


ensembl_gene_id: Shew_2329
symbol: Shew_2329
gene_biotype: protein_coding
description:
  PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: she:Shewmr4_2432 response regulator receiver protein.


ensembl_gene_id: Shew_2334
symbol: secF
gene_biotype: protein_coding
description:
  Protein translocase subunit secF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: Shew_2335
symbol: secD
gene_biotype: protein_coding
description:
  Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: Shew_2336
symbol: yajC
gene_biotype: protein_coding
description:
  Protein translocase subunit yajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: Shew_2337
symbol: tgt
gene_biotype: protein_coding
description:
  Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...]


ensembl_gene_id: Shew_2338
symbol: queA
gene_biotype: protein_coding
description:
  S-adenosylmethionine--tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: Shew_2341
symbol: Shew_2341
gene_biotype: protein_coding
description:
  Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sdn:Sden_1366 sigma-54 factor, interaction region.


ensembl_gene_id: Shew_2342
symbol: Shew_2342
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sdn:Sden_1365 ATP-binding region, ATPase-like protein.


ensembl_gene_id: Shew_2345
symbol: Shew_2345
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdn:Sden_1897 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Shew_2346
symbol: Shew_2346
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: cps:CPS_3310 putative phosphonate ABC transporter, ATP-binding protein.


ensembl_gene_id: Shew_2347
symbol: Shew_2347
gene_biotype: protein_coding
description:
  TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: sfr:Sfri_2485 phosphonate ABC transporter, periplasmic phosphonate-binding protein.


ensembl_gene_id: Shew_2348
symbol: Shew_2348
gene_biotype: protein_coding
description:
  Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_1655 two component transcriptional regulator, winged helix family.


ensembl_gene_id: Shew_2349
symbol: Shew_2349
gene_biotype: protein_coding
description:
  Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: she:Shewmr4_1579 periplasmic sensor signal transduction histidine kinase.


ensembl_gene_id: Shew_2350
symbol: Shew_2350
gene_biotype: protein_coding
description:
  PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: son:SO1944 hypothetical protein.


ensembl_gene_id: Shew_2351
symbol: Shew_2351
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1652 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region.


ensembl_gene_id: Shew_2353
symbol: corA
gene_biotype: protein_coding
description:
  Magnesium and cobalt transport protein CorA; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: Shew_2357
symbol: Shew_2357
gene_biotype: protein_coding
description:
  TIGRFAM: D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; KEGG: son:SO2851 histidinol phosphatase domain protein.


ensembl_gene_id: Shew_2358
symbol: Shew_2358
gene_biotype: protein_coding
description:
  PFAM: peptidase M24; peptidase M24B, X-Pro dipeptidase/aminopeptidase domain protein; KEGG: mca:MCA2770 xaa-pro aminopeptidase.


ensembl_gene_id: Shew_2360
symbol: Shew_2360
gene_biotype: protein_coding
description:
  D-amino-acid dehydrogenase; PFAM: FAD dependent oxidoreductase; KEGG: hch:HCH_03166 glycine/D-amino acid oxidases (deaminating).


ensembl_gene_id: Shew_2361
symbol: Shew_2361
gene_biotype: protein_coding
description:
  PFAM: proline racemase; KEGG: cps:CPS_1453 putative proline racemase; Belongs to the proline racemase family.


ensembl_gene_id: Shew_2363
symbol: Shew_2363
gene_biotype: protein_coding
description:
  Proline racemase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate. Displays no proline racemase activity.


ensembl_gene_id: Shew_2365
symbol: Shew_2365
gene_biotype: protein_coding
description:
  Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: she:Shewmr4_1521 transcriptional regulator, GntR family.


ensembl_gene_id: Shew_2366
symbol: fabH-2
gene_biotype: protein_coding
description:
  3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: Shew_2368
symbol: Shew_2368
gene_biotype: protein_coding
description:
  PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: she:Shewmr4_1516 exonuclease, RNase T and DNA polymerase III.


ensembl_gene_id: Shew_2369
symbol: Shew_2369
gene_biotype: protein_coding
description:
  PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: son:SO2856 CBS domain protein.


ensembl_gene_id: Shew_2370
symbol: Shew_2370
gene_biotype: protein_coding
description:
  PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sdn:Sden_1373 methyltransferase type 12.


ensembl_gene_id: Shew_2371
symbol: Shew_2371
gene_biotype: protein_coding
description:
  PFAM: Na+/solute symporter; KEGG: sfr:Sfri_1547 Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Shew_2375
symbol: Shew_2375
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_1510 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region.


ensembl_gene_id: Shew_2377
symbol: ligA
gene_biotype: protein_coding
description:
  DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.


ensembl_gene_id: Shew_2378
symbol: zipA
gene_biotype: protein_coding
description:
  Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: Shew_2379
symbol: smc
gene_biotype: protein_coding
description:
  Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.


ensembl_gene_id: Shew_2380
symbol: cysZ
gene_biotype: protein_coding
description:
  Protein of unknown function DUF540; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: Shew_2382
symbol: Shew_2382
gene_biotype: protein_coding
description:
  TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: she:Shewmr4_1500 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.


ensembl_gene_id: Shew_2385
symbol: Shew_2385
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_2119 TonB-dependent receptor.


ensembl_gene_id: Shew_2386
symbol: Shew_2386
gene_biotype: protein_coding
description:
  PFAM: C4-dicarboxylate anaerobic carrier; KEGG: shm:Shewmr7_1563 C4-dicarboxylate anaerobic carrier.


ensembl_gene_id: Shew_2387
symbol: Shew_2387
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_2469 transcriptional regulator, LysR family protein.


ensembl_gene_id: Shew_2388
symbol: Shew_2388
gene_biotype: protein_coding
description:
  PFAM: formate/nitrite transporter; CBS domain containing protein; KEGG: sfr:Sfri_2470 formate/nitrite transporter.


ensembl_gene_id: Shew_2390
symbol: Shew_2390
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1561 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL.


ensembl_gene_id: Shew_2391
symbol: Shew_2391
gene_biotype: protein_coding
description:
  Pyruvate formate-lyase activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: Shew_2392
symbol: Shew_2392
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF412; KEGG: shm:Shewmr7_1559 protein of unknown function DUF412.


ensembl_gene_id: Shew_2393
symbol: ackA
gene_biotype: protein_coding
description:
  Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: Shew_2394
symbol: Shew_2394
gene_biotype: protein_coding
description:
  Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: Shew_2398
symbol: Shew_2398
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_1550 protein of unknown function UPF0118.


ensembl_gene_id: Shew_2400
symbol: Shew_2400
gene_biotype: protein_coding
description:
  Domain of unknown function DUF1731; PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain; domain of unknown function DUF1731; KEGG: she:Shewmr4_1483 hypothetical protein.


ensembl_gene_id: Shew_2401
symbol: Shew_2401
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_1545 protein of unknown function DUF214.


ensembl_gene_id: Shew_2402
symbol: Shew_2402
gene_biotype: protein_coding
description:
  PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sdn:Sden_2367 ABC transporter-related protein.


ensembl_gene_id: Shew_2406
symbol: Shew_2406
gene_biotype: protein_coding
description:
  Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: she:Shewmr4_1471 transcriptional regulator, AraC family.


ensembl_gene_id: Shew_2407
symbol: Shew_2407
gene_biotype: protein_coding
description:
  PFAM: peptidase S49; Peptidase S49, N-terminal domain protein; KEGG: she:Shewmr4_1470 peptidase S49, N-terminal domain protein.


ensembl_gene_id: Shew_2409
symbol: Shew_2409
gene_biotype: protein_coding
description:
  PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1534 short-chain dehydrogenase/reductase SDR.


ensembl_gene_id: Shew_2410
symbol: Shew_2410
gene_biotype: protein_coding
description:
  PFAM: beta-ketoacyl synthase; KEGG: sfr:Sfri_1391 beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.


ensembl_gene_id: Shew_2411
symbol: mnmC
gene_biotype: protein_coding
description:
  FAD dependent oxidoreductase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.


ensembl_gene_id: Shew_2415
symbol: Shew_2415
gene_biotype: protein_coding
description:
  PFAM: nucleoside:H+ symporter; major facilitator superfamily MFS_1; KEGG: son:SO3078 major facilitator family protein, putative.


ensembl_gene_id: Shew_2416
symbol: aroC
gene_biotype: protein_coding
description:
  Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: Shew_2417
symbol: prmB
gene_biotype: protein_coding
description:
  Modification methylase, HemK family; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: Shew_2419
symbol: Shew_2419
gene_biotype: protein_coding
description:
  TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_1413 phosphohistidine phosphatase, SixA.


ensembl_gene_id: Shew_2420
symbol: Shew_2420
gene_biotype: protein_coding
description:
  PFAM: peptidase M16 domain protein; KEGG: son:SO3083 peptidase, M16 family; Belongs to the peptidase M16 family.


ensembl_gene_id: Shew_2421
symbol: Shew_2421
gene_biotype: protein_coding
description:
  KEGG: shm:Shewmr7_1476 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.


ensembl_gene_id: Shew_2425
symbol: fadJ
gene_biotype: protein_coding
description:
  3-hydroxyacyl-CoA dehydrogenase / short chain enoyl-CoA hydratase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: Shew_2427
symbol: Shew_2427
gene_biotype: protein_coding
description:
  PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shm:Shewmr7_1471 ATPase associated with various cellular activities, AAA_3.


ensembl_gene_id: Shew_2431
symbol: Shew_2431
gene_biotype: protein_coding
description:
  PFAM: TPR repeat-containing protein; von Willebrand factor, type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_1467 tetratricopeptide TPR_2 repeat protein.


ensembl_gene_id: Shew_2433
symbol: Shew_2433
gene_biotype: protein_coding
description:
  RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sdn:Sden_1522 sigma-70 region 2; Belongs to the sigma-70 factor family. ECF subfamily.


ensembl_gene_id: Shew_2435
symbol: Shew_2435
gene_biotype: protein_coding
description:
  Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: Shew_2436
symbol: Shew_2436
gene_biotype: protein_coding
description:
  PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: shm:Shewmr7_1462 membrane protein involved in aromatic hydrocarbon degradation.


ensembl_gene_id: Shew_2439
symbol: Shew_2439
gene_biotype: protein_coding
description:
  TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1394 efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: Shew_2440
symbol: Shew_2440
gene_biotype: protein_coding
description:
  PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1458 acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.


ensembl_gene_id: Shew_2443
symbol: Shew_2443
gene_biotype: protein_coding
description:
  PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Proprotein convertase, P; protease-associated PA domain protein; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: sfr:Sfri_2692 peptidase S8 and S53, subtilisin, kexin, sedolisin.


ensembl_gene_id: Shew_2446
symbol: ribA
gene_biotype: protein_coding
description:
  GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.


ensembl_gene_id: Shew_2448
symbol: Shew_2448
gene_biotype: protein_coding
description:
  Ribonucleoside-triphosphate reductase class III activase subunit; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: Shew_2449
symbol: Shew_2449
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_2441 anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein.


ensembl_gene_id: Shew_2452
symbol: Shew_2452
gene_biotype: protein_coding
description:
  PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO2838 ATP-dependent RNA helicase, DEAD box family; Belongs to the DEAD box helicase family.


ensembl_gene_id: Shew_2455
symbol: Shew_2455
gene_biotype: protein_coding
description:
  PFAM: peptidase M23B; Opacity-associated protein A; Opacity-associated protein A, N-terminal domain protein; KEGG: shm:Shewmr7_2518 peptidase M23B.


ensembl_gene_id: Shew_2457
symbol: sbcD
gene_biotype: protein_coding
description:
  Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: Shew_2458
symbol: Shew_2458
gene_biotype: protein_coding
description:
  PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: vpa:VPA1298 putative glutathione S-transferase; Belongs to the GST superfamily.


ensembl_gene_id: Shew_2465
symbol: Shew_2465
gene_biotype: protein_coding
description:
  Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_2452 transcriptional regulator, LysR family.


ensembl_gene_id: Shew_2467
symbol: Shew_2467
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF1260; KEGG: shm:Shewmr7_2523 protein of unknown function DUF1260.


ensembl_gene_id: Shew_2470
symbol: Shew_2470
gene_biotype: protein_coding
description:
  PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: shm:Shewmr7_2526 PpiC-type peptidyl-prolyl cis-trans isomerase.


ensembl_gene_id: Shew_2472
symbol: Shew_2472
gene_biotype: protein_coding
description:
  TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2528 diguanylate cyclase.


ensembl_gene_id: Shew_2474
symbol: Shew_2474
gene_biotype: protein_coding
description:
  TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: Shew_2475
symbol: Shew_2475
gene_biotype: protein_coding
description:
  PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sdn:Sden_2422 biopolymer transport protein ExbD/TolR.


ensembl_gene_id: Shew_2480
symbol: Shew_2480
gene_biotype: protein_coding
description:
  PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2628 TonB-dependent receptor.


ensembl_gene_id: Shew_2482
symbol: Shew_2482
gene_biotype: protein_coding
description:
  PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: she:Shewmr4_2469 DNA polymerase B region.


ensembl_gene_id: Shew_2489
symbol: Shew_2489
gene_biotype: protein_coding
description:
  KEGG: she:Shewmr4_2476 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1.


ensembl_gene_id: Shew_2490
symbol: Shew_2490
gene_biotype: protein_coding
description:
  TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: shm:Shewmr7_3574 anion transporter.


ensembl_gene_id: Shew_2491
symbol: Shew_2491
gene_biotype: protein_coding
description:
  Methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO1812 methionine gamma-lyase.


ensembl_gene_id: Shew_2493
symbol: Shew_2493
gene_biotype: protein_coding
description:
  PFAM: protein of unknown function DUF463, YcjX family protein; KEGG: sfr:Sfri_2575 protein of unknown function DUF463, YcjX family protein.


ensembl_gene_id: Shew_2496
symbol: Shew_2496
gene_biotype: protein_coding
description:
  Phage shock protein A, PspA; PFAM: PspA/IM30 family protein; KEGG: shm:Shewmr7_2550 phage shock protein A, PspA.


ensembl_gene_id: Shew_2497
symbol: Shew_2497
gene_biotype: protein_coding
description:
  Sigma54 specific transcriptional regulator, Fis family; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_2551 transcriptional regulator, fis family.


ensembl_gene_id: Shew_2498
symbol: Shew_2498
gene_biotype: protein_coding
description:
  PFAM: extracellular solute-binding protein, family 5; KEGG: she:Shewmr4_2484 extracellular solute-binding protein, family 5.


ensembl_gene_id: Shew_2499
symbol: Shew_2499
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2553 binding-protein-dependent transport systems inner membrane component.


ensembl_gene_id: Shew_2500
symbol: Shew_2500
gene_biotype: protein_coding
description:
  PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2554 binding-protein-dependent transport systems inner membrane component.


