# geneInfo

ensembl_gene_id: GCA_001297775_00002
symbol: fusA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.


ensembl_gene_id: GCA_001297775_00003
symbol: rpsG
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.


ensembl_gene_id: GCA_001297775_00004
symbol: rpsL
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.


ensembl_gene_id: GCA_001297775_00005
symbol: tusB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.


ensembl_gene_id: GCA_001297775_00007
symbol: tusD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.


ensembl_gene_id: GCA_001297775_00013
symbol: kefB
gene_biotype: protein_coding
description:
  Unannotated protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.


ensembl_gene_id: GCA_001297775_00014
symbol: kefG
gene_biotype: protein_coding
description:
  Unannotated protein; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.


ensembl_gene_id: GCA_001297775_00023
symbol: argD
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.


ensembl_gene_id: GCA_001297775_00027
symbol: GM31_05455
gene_biotype: protein_coding
description:
  Unannotated protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.


ensembl_gene_id: GCA_001297775_00032
symbol: cysG
gene_biotype: protein_coding
description:
  Unannotated protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family.  In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.


ensembl_gene_id: GCA_001297775_00042
symbol: trpS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.


ensembl_gene_id: GCA_001297775_00043
symbol: GM31_05375
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.


ensembl_gene_id: GCA_001297775_00047
symbol: aroB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).


ensembl_gene_id: GCA_001297775_00048
symbol: aroK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.


ensembl_gene_id: GCA_001297775_00058
symbol: hslO
gene_biotype: protein_coding
description:
  Unannotated protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.


ensembl_gene_id: GCA_001297775_00059
symbol: pckA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.


ensembl_gene_id: GCA_001297775_00062
symbol: greB
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.


ensembl_gene_id: GCA_001297775_00065
symbol: feoB
gene_biotype: protein_coding
description:
  Unannotated protein; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.


ensembl_gene_id: GCA_001297775_00068
symbol: bioH
gene_biotype: protein_coding
description:
  Unannotated protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.


ensembl_gene_id: GCA_001297775_00070
symbol: nfuA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.


ensembl_gene_id: GCA_001297775_00073
symbol: GM31_05220
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.


ensembl_gene_id: GCA_001297775_00077
symbol: malT
gene_biotype: protein_coding
description:
  Unannotated protein; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.


ensembl_gene_id: GCA_001297775_00080
symbol: glpE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.


ensembl_gene_id: GCA_001297775_00084
symbol: glgC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.


ensembl_gene_id: GCA_001297775_00085
symbol: glgX
gene_biotype: protein_coding
description:
  Unannotated protein; Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.


ensembl_gene_id: GCA_001297775_00086
symbol: glgB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.


ensembl_gene_id: GCA_001297775_00087
symbol: asd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.


ensembl_gene_id: GCA_001297775_00096
symbol: ugpC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family.


ensembl_gene_id: GCA_001297775_00097
symbol: ugpE
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.


ensembl_gene_id: GCA_001297775_00105
symbol: panZ
gene_biotype: protein_coding
description:
  Unannotated protein; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family.


ensembl_gene_id: GCA_001297775_00107
symbol: GM31_02500
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: GCA_001297775_00109
symbol: rpoH
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.


ensembl_gene_id: GCA_001297775_00110
symbol: ftsX
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.


ensembl_gene_id: GCA_001297775_00112
symbol: ftsY
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.


ensembl_gene_id: GCA_001297775_00113
symbol: rsmD
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.


ensembl_gene_id: GCA_001297775_00118
symbol: tusA
gene_biotype: protein_coding
description:
  Unannotated protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.


ensembl_gene_id: GCA_001297775_00119
symbol: GM31_02440
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.


ensembl_gene_id: GCA_001297775_00123
symbol: arnF
gene_biotype: protein_coding
description:
  Unannotated protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family.


ensembl_gene_id: GCA_001297775_00124
symbol: arnE
gene_biotype: protein_coding
description:
  Unannotated protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family.


ensembl_gene_id: GCA_001297775_00126
symbol: arnD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.


ensembl_gene_id: GCA_001297775_00127
symbol: arnA
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily.


ensembl_gene_id: GCA_001297775_00128
symbol: arnC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.


ensembl_gene_id: GCA_001297775_00129
symbol: arnB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.


ensembl_gene_id: GCA_001297775_00133
symbol: nikD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.


ensembl_gene_id: GCA_001297775_00135
symbol: nikR
gene_biotype: protein_coding
description:
  Unannotated protein; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.


ensembl_gene_id: GCA_001297775_00139
symbol: GM31_14300
gene_biotype: protein_coding
description:
  Unannotated protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.


ensembl_gene_id: GCA_001297775_00140
symbol: tppB
gene_biotype: protein_coding
description:
  Unannotated protein; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily.


ensembl_gene_id: GCA_001297775_00145
symbol: treF
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity.


ensembl_gene_id: GCA_001297775_00155
symbol: dctA
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: GCA_001297775_00159
symbol: GM31_14200
gene_biotype: protein_coding
description:
  Unannotated protein; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.


ensembl_gene_id: GCA_001297775_00160
symbol: bcsA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.


ensembl_gene_id: GCA_001297775_00182
symbol: ghrB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.


ensembl_gene_id: GCA_001297775_00189
symbol: wecH
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units.


ensembl_gene_id: GCA_001297775_00193
symbol: xylG
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.


ensembl_gene_id: GCA_001297775_00209
symbol: selA
gene_biotype: protein_coding
description:
  Unannotated protein; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family.


ensembl_gene_id: GCA_001297775_00217
symbol: GM31_06645
gene_biotype: protein_coding
description:
  Unannotated protein; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.


ensembl_gene_id: GCA_001297775_00219
symbol: lldD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.


ensembl_gene_id: GCA_001297775_00220
symbol: trmL
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.


ensembl_gene_id: GCA_001297775_00223
symbol: secB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.


ensembl_gene_id: GCA_001297775_00224
symbol: GM31_06680
gene_biotype: protein_coding
description:
  Unannotated protein; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.


ensembl_gene_id: GCA_001297775_00231
symbol: tdh
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.


ensembl_gene_id: GCA_001297775_00233
symbol: rfaD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.


ensembl_gene_id: GCA_001297775_00244
symbol: GM31_06780
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.


ensembl_gene_id: GCA_001297775_00246
symbol: coaD
gene_biotype: protein_coding
description:
  Unannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.


ensembl_gene_id: GCA_001297775_00247
symbol: mutM
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.


ensembl_gene_id: GCA_001297775_00251
symbol: GM31_06820
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.


ensembl_gene_id: GCA_001297775_00252
symbol: dut
gene_biotype: protein_coding
description:
  Unannotated protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.


ensembl_gene_id: GCA_001297775_00253
symbol: slmA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.


ensembl_gene_id: GCA_001297775_00254
symbol: pyrE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).


ensembl_gene_id: GCA_001297775_00255
symbol: rph
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.


ensembl_gene_id: GCA_001297775_00258
symbol: ligB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily.


ensembl_gene_id: GCA_001297775_00260
symbol: rpoZ
gene_biotype: protein_coding
description:
  Unannotated protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.


ensembl_gene_id: GCA_001297775_00261
symbol: GM31_06870
gene_biotype: protein_coding
description:
  Unannotated protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.


ensembl_gene_id: GCA_001297775_00262
symbol: trmH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: GCA_001297775_00263
symbol: recG
gene_biotype: protein_coding
description:
  Unannotated protein; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.


ensembl_gene_id: GCA_001297775_00268
symbol: tpiA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.


ensembl_gene_id: GCA_001297775_00273
symbol: fabR
gene_biotype: protein_coding
description:
  Unannotated protein; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.


ensembl_gene_id: GCA_001297775_00274
symbol: sthA
gene_biotype: protein_coding
description:
  Unannotated protein; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.


ensembl_gene_id: GCA_001297775_00278
symbol: argC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_00284
symbol: murQ
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.


ensembl_gene_id: GCA_001297775_00287
symbol: nepI
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the efflux of purine ribonucleosides, such as guanosine, adenosine and especially inosine. Involved in the resistance to 6-mercaptopurine; Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.


ensembl_gene_id: GCA_001297775_00306
symbol: ibpB
gene_biotype: protein_coding
description:
  Unannotated protein; Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.


ensembl_gene_id: GCA_001297775_00307
symbol: ibpA
gene_biotype: protein_coding
description:
  Unannotated protein; Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.


ensembl_gene_id: GCA_001297775_00316
symbol: gyrB
gene_biotype: protein_coding
description:
  Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.


ensembl_gene_id: GCA_001297775_00317
symbol: recF
gene_biotype: protein_coding
description:
  Unannotated protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.


ensembl_gene_id: GCA_001297775_00318
symbol: GM31_05625
gene_biotype: protein_coding
description:
  Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication  [...]


ensembl_gene_id: GCA_001297775_00319
symbol: dnaA
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.


ensembl_gene_id: GCA_001297775_00320
symbol: rnpA
gene_biotype: protein_coding
description:
  Unannotated protein; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.


ensembl_gene_id: GCA_001297775_00321
symbol: yidC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.


ensembl_gene_id: GCA_001297775_00322
symbol: trmE
gene_biotype: protein_coding
description:
  Unannotated protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.


ensembl_gene_id: GCA_001297775_00327
symbol: GM31_05670
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.


ensembl_gene_id: GCA_001297775_00328
symbol: pstB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.


ensembl_gene_id: GCA_001297775_00330
symbol: pstC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: GCA_001297775_00331
symbol: GM31_05690
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.


ensembl_gene_id: GCA_001297775_00332
symbol: glmS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.


ensembl_gene_id: GCA_001297775_00333
symbol: glmU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.


ensembl_gene_id: GCA_001297775_00334
symbol: atpC
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.


ensembl_gene_id: GCA_001297775_00335
symbol: atpD
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.


ensembl_gene_id: GCA_001297775_00336
symbol: atpG
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.


ensembl_gene_id: GCA_001297775_00337
symbol: atpA
gene_biotype: protein_coding
description:
  Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.


ensembl_gene_id: GCA_001297775_00338
symbol: atpH
gene_biotype: protein_coding
description:
  Unannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.


ensembl_gene_id: GCA_001297775_00339
symbol: atpF
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.


ensembl_gene_id: GCA_001297775_00341
symbol: atpB
gene_biotype: protein_coding
description:
  Unannotated protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.


ensembl_gene_id: GCA_001297775_00343
symbol: gidB
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.


ensembl_gene_id: GCA_001297775_00344
symbol: mnmG
gene_biotype: protein_coding
description:
  Unannotated protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.


ensembl_gene_id: GCA_001297775_00350
symbol: trkD
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family.


ensembl_gene_id: GCA_001297775_00352
symbol: rbsA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.


ensembl_gene_id: GCA_001297775_00355
symbol: rbsK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.


ensembl_gene_id: GCA_001297775_00368
symbol: GM31_07380
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.


ensembl_gene_id: GCA_001297775_00369
symbol: ung
gene_biotype: protein_coding
description:
  Unannotated protein; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.


ensembl_gene_id: GCA_001297775_00371
symbol: srmB
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily.


ensembl_gene_id: GCA_001297775_00372
symbol: GM31_07400
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).


ensembl_gene_id: GCA_001297775_00375
symbol: GM31_07415
gene_biotype: protein_coding
description:
  Unannotated protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degradi [...]


ensembl_gene_id: GCA_001297775_00378
symbol: lepA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.


ensembl_gene_id: GCA_001297775_00380
symbol: rnc
gene_biotype: protein_coding
description:
  Unannotated protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.


ensembl_gene_id: GCA_001297775_00381
symbol: era
gene_biotype: protein_coding
description:
  Unannotated protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.


ensembl_gene_id: GCA_001297775_00383
symbol: pdxJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.


ensembl_gene_id: GCA_001297775_00384
symbol: acpS
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.


ensembl_gene_id: GCA_001297775_00388
symbol: tadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.


ensembl_gene_id: GCA_001297775_00389
symbol: mltF
gene_biotype: protein_coding
description:
  Unannotated protein; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.


ensembl_gene_id: GCA_001297775_00390
symbol: purL
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.


ensembl_gene_id: GCA_001297775_00395
symbol: hmp
gene_biotype: protein_coding
description:
  Unannotated protein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.


ensembl_gene_id: GCA_001297775_00396
symbol: glyA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.


ensembl_gene_id: GCA_001297775_00406
symbol: GM31_08995
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.


ensembl_gene_id: GCA_001297775_00411
symbol: trmJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.


ensembl_gene_id: GCA_001297775_00412
symbol: iscR
gene_biotype: protein_coding
description:
  Unannotated protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.


ensembl_gene_id: GCA_001297775_00413
symbol: iscS
gene_biotype: protein_coding
description:
  Unannotated protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.


ensembl_gene_id: GCA_001297775_00414
symbol: GM31_08950
gene_biotype: protein_coding
description:
  Unannotated protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.


ensembl_gene_id: GCA_001297775_00415
symbol: iscA
gene_biotype: protein_coding
description:
  Unannotated protein; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.


ensembl_gene_id: GCA_001297775_00416
symbol: hscB
gene_biotype: protein_coding
description:
  Unannotated protein; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.


ensembl_gene_id: GCA_001297775_00417
symbol: hscA
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.


ensembl_gene_id: GCA_001297775_00425
symbol: ndk
gene_biotype: protein_coding
description:
  Unannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.


ensembl_gene_id: GCA_001297775_00426
symbol: rlmN
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.


ensembl_gene_id: GCA_001297775_00427
symbol: GM31_08885
gene_biotype: protein_coding
description:
  Unannotated protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. Belongs to the RodZ family.


ensembl_gene_id: GCA_001297775_00428
symbol: ispG
gene_biotype: protein_coding
description:
  Unannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.


ensembl_gene_id: GCA_001297775_00431
symbol: bamB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.


ensembl_gene_id: GCA_001297775_00432
symbol: der
gene_biotype: protein_coding
description:
  Unannotated protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.


ensembl_gene_id: GCA_001297775_00436
symbol: xseA
gene_biotype: protein_coding
description:
  Unannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.


ensembl_gene_id: GCA_001297775_00437
symbol: guaB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.


ensembl_gene_id: GCA_001297775_00443
symbol: ppk
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.


ensembl_gene_id: GCA_001297775_00444
symbol: purN
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.


ensembl_gene_id: GCA_001297775_00447
symbol: upp
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.


ensembl_gene_id: GCA_001297775_00449
symbol: hda
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA; Belongs to the DnaA family. HdA subfamily.


ensembl_gene_id: GCA_001297775_00452
symbol: GM31_08760
gene_biotype: protein_coding
description:
  Unannotated protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.


ensembl_gene_id: GCA_001297775_00455
symbol: bepA
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.


ensembl_gene_id: GCA_001297775_00459
symbol: dapA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).


ensembl_gene_id: GCA_001297775_00463
symbol: tmcA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).


ensembl_gene_id: GCA_001297775_00466
symbol: dapE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.


ensembl_gene_id: GCA_001297775_00472
symbol: GM31_08660
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.


ensembl_gene_id: GCA_001297775_00474
symbol: hemF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.


ensembl_gene_id: GCA_001297775_00480
symbol: nudI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP); Belongs to the Nudix hydrolase family. NudI subfamily.


ensembl_gene_id: GCA_001297775_00485
symbol: GM31_08605
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: GCA_001297775_00487
symbol: cysA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_001297775_00491
symbol: GM31_08575
gene_biotype: protein_coding
description:
  Unannotated protein; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).


ensembl_gene_id: GCA_001297775_00494
symbol: cysZ
gene_biotype: protein_coding
description:
  Unannotated protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family.


ensembl_gene_id: GCA_001297775_00495
symbol: zipA
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.


ensembl_gene_id: GCA_001297775_00496
symbol: ligA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.


ensembl_gene_id: GCA_001297775_00504
symbol: gltX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).


ensembl_gene_id: GCA_001297775_00511
symbol: mntH
gene_biotype: protein_coding
description:
  Unannotated protein; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.


ensembl_gene_id: GCA_001297775_00529
symbol: napD
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.


ensembl_gene_id: GCA_001297775_00533
symbol: napB
gene_biotype: protein_coding
description:
  Unannotated protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.


ensembl_gene_id: GCA_001297775_00535
symbol: ccmA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.


ensembl_gene_id: GCA_001297775_00536
symbol: GM31_12770
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.


ensembl_gene_id: GCA_001297775_00537
symbol: ccmC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.


ensembl_gene_id: GCA_001297775_00538
symbol: GM31_12780
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family.


ensembl_gene_id: GCA_001297775_00539
symbol: ccmE
gene_biotype: protein_coding
description:
  Unannotated protein; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.


ensembl_gene_id: GCA_001297775_00544
symbol: nrfA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family.


ensembl_gene_id: GCA_001297775_00571
symbol: GM31_01265
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.


ensembl_gene_id: GCA_001297775_00651
symbol: GM31_07960
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.


ensembl_gene_id: GCA_001297775_00657
symbol: rimO
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.


ensembl_gene_id: GCA_001297775_00679
symbol: GM31_07720
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family.


ensembl_gene_id: GCA_001297775_00680
symbol: potG
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_001297775_00684
symbol: rumB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.


ensembl_gene_id: GCA_001297775_00685
symbol: metG
gene_biotype: protein_coding
description:
  Unannotated protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.


ensembl_gene_id: GCA_001297775_00686
symbol: GM31_07685
gene_biotype: protein_coding
description:
  Unannotated protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.


ensembl_gene_id: GCA_001297775_00689
symbol: thiM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.


ensembl_gene_id: GCA_001297775_00698
symbol: GM31_07635
gene_biotype: protein_coding
description:
  Unannotated protein; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.


ensembl_gene_id: GCA_001297775_00703
symbol: mdtC
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.


ensembl_gene_id: GCA_001297775_00704
symbol: mdtB
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.


ensembl_gene_id: GCA_001297775_00723
symbol: fcl
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.


ensembl_gene_id: GCA_001297775_00746
symbol: GM31_13720
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.


ensembl_gene_id: GCA_001297775_00754
symbol: hisF
gene_biotype: protein_coding
description:
  Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.


ensembl_gene_id: GCA_001297775_00756
symbol: hisH
gene_biotype: protein_coding
description:
  Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.


ensembl_gene_id: GCA_001297775_00758
symbol: hisC
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.


ensembl_gene_id: GCA_001297775_00759
symbol: hisD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.


ensembl_gene_id: GCA_001297775_00760
symbol: hisG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).


ensembl_gene_id: GCA_001297775_00766
symbol: sbmC
gene_biotype: protein_coding
description:
  Unannotated protein; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.


ensembl_gene_id: GCA_001297775_00769
symbol: cobU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.


ensembl_gene_id: GCA_001297775_00770
symbol: cobS
gene_biotype: protein_coding
description:
  Unannotated protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.


ensembl_gene_id: GCA_001297775_00771
symbol: cobT
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).


ensembl_gene_id: GCA_001297775_00784
symbol: GM31_20000
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family.


ensembl_gene_id: GCA_001297775_00793
symbol: aroQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.


ensembl_gene_id: GCA_001297775_00816
symbol: amn
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.


ensembl_gene_id: GCA_001297775_00833
symbol: gloB
gene_biotype: protein_coding
description:
  Unannotated protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.


ensembl_gene_id: GCA_001297775_00836
symbol: dnaQ
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.


ensembl_gene_id: GCA_001297775_00840
symbol: gmhA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.


ensembl_gene_id: GCA_001297775_00843
symbol: nqrA
gene_biotype: protein_coding
description:
  Unannotated protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.


ensembl_gene_id: GCA_001297775_00846
symbol: nqrD
gene_biotype: protein_coding
description:
  Unannotated protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.


ensembl_gene_id: GCA_001297775_00848
symbol: nqrF
gene_biotype: protein_coding
description:
  Unannotated protein; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.


ensembl_gene_id: GCA_001297775_00850
symbol: dinB
gene_biotype: protein_coding
description:
  Unannotated protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.


ensembl_gene_id: GCA_001297775_00852
symbol: gpt
gene_biotype: protein_coding
description:
  Unannotated protein; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.


ensembl_gene_id: GCA_001297775_00854
symbol: crl
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family.


ensembl_gene_id: GCA_001297775_00856
symbol: proB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.


ensembl_gene_id: GCA_001297775_00857
symbol: proA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.


ensembl_gene_id: GCA_001297775_00875
symbol: tauB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.


ensembl_gene_id: GCA_001297775_00890
symbol: iraP
gene_biotype: protein_coding
description:
  Unannotated protein; Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.


ensembl_gene_id: GCA_001297775_00897
symbol: ppnP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.


ensembl_gene_id: GCA_001297775_00900
symbol: sbcC
gene_biotype: protein_coding
description:
  Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily.


ensembl_gene_id: GCA_001297775_00901
symbol: sbcD
gene_biotype: protein_coding
description:
  Unannotated protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.


ensembl_gene_id: GCA_001297775_00914
symbol: acpH
gene_biotype: protein_coding
description:
  Unannotated protein; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family.


ensembl_gene_id: GCA_001297775_00915
symbol: queA
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).


ensembl_gene_id: GCA_001297775_00916
symbol: tgt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  [...]


ensembl_gene_id: GCA_001297775_00917
symbol: yajC
gene_biotype: protein_coding
description:
  Unannotated protein; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.


ensembl_gene_id: GCA_001297775_00918
symbol: secD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.


ensembl_gene_id: GCA_001297775_00924
symbol: nrdR
gene_biotype: protein_coding
description:
  Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.


ensembl_gene_id: GCA_001297775_00925
symbol: ribD
gene_biotype: protein_coding
description:
  Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.


ensembl_gene_id: GCA_001297775_00926
symbol: ribH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.


ensembl_gene_id: GCA_001297775_00927
symbol: nusB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.


ensembl_gene_id: GCA_001297775_00928
symbol: thiL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.


ensembl_gene_id: GCA_001297775_00929
symbol: GM31_03865
gene_biotype: protein_coding
description:
  Unannotated protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).


ensembl_gene_id: GCA_001297775_00931
symbol: dxs
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.


ensembl_gene_id: GCA_001297775_00933
symbol: xseB
gene_biotype: protein_coding
description:
  Unannotated protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.


ensembl_gene_id: GCA_001297775_00934
symbol: thiI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.


ensembl_gene_id: GCA_001297775_00939
symbol: cyoE
gene_biotype: protein_coding
description:
  Unannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.


ensembl_gene_id: GCA_001297775_00947
symbol: tig
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.


ensembl_gene_id: GCA_001297775_00948
symbol: clpP
gene_biotype: protein_coding
description:
  Unannotated protein; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.


ensembl_gene_id: GCA_001297775_00949
symbol: clpX
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.


ensembl_gene_id: GCA_001297775_00950
symbol: lon
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.


ensembl_gene_id: GCA_001297775_00951
symbol: GM31_03755
gene_biotype: protein_coding
description:
  Unannotated protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.


ensembl_gene_id: GCA_001297775_00957
symbol: queC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.


ensembl_gene_id: GCA_001297775_00959
symbol: cof
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5- hydroxymethylpyrimidine phosphate (HMP-P).


ensembl_gene_id: GCA_001297775_00997
symbol: apt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.


ensembl_gene_id: GCA_001297775_00998
symbol: dnaX
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.


ensembl_gene_id: GCA_001297775_00999
symbol: GM31_03530
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.


ensembl_gene_id: GCA_001297775_01000
symbol: recR
gene_biotype: protein_coding
description:
  Unannotated protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.


ensembl_gene_id: GCA_001297775_01002
symbol: adk
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.


ensembl_gene_id: GCA_001297775_01003
symbol: hemH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.


ensembl_gene_id: GCA_001297775_01005
symbol: GM31_03495
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.


ensembl_gene_id: GCA_001297775_01022
symbol: purK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).


ensembl_gene_id: GCA_001297775_01023
symbol: purE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).


ensembl_gene_id: GCA_001297775_01026
symbol: lpxH
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_001297775_01033
symbol: folD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.


ensembl_gene_id: GCA_001297775_01041
symbol: glaH
gene_biotype: protein_coding
description:
  Unannotated protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.


ensembl_gene_id: GCA_001297775_01042
symbol: lhgD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2HGDH family.


ensembl_gene_id: GCA_001297775_01069
symbol: phnC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.


ensembl_gene_id: GCA_001297775_01073
symbol: GM31_01455
gene_biotype: protein_coding
description:
  Unannotated protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.


ensembl_gene_id: GCA_001297775_01091
symbol: GM31_12175
gene_biotype: protein_coding
description:
  Unannotated protein; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.


ensembl_gene_id: GCA_001297775_01098
symbol: rcsA
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds to DNA to regulate expression of genes.


ensembl_gene_id: GCA_001297775_01101
symbol: fliP
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.


ensembl_gene_id: GCA_001297775_01103
symbol: fliN
gene_biotype: protein_coding
description:
  Unannotated protein; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.


ensembl_gene_id: GCA_001297775_01104
symbol: fliM
gene_biotype: protein_coding
description:
  Unannotated protein; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: GCA_001297775_01105
symbol: fliL
gene_biotype: protein_coding
description:
  Unannotated protein; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.


ensembl_gene_id: GCA_001297775_01110
symbol: fliG
gene_biotype: protein_coding
description:
  Unannotated protein; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.


ensembl_gene_id: GCA_001297775_01111
symbol: GM31_12275
gene_biotype: protein_coding
description:
  Unannotated protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.


ensembl_gene_id: GCA_001297775_01118
symbol: GM31_12315
gene_biotype: protein_coding
description:
  Unannotated protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.


ensembl_gene_id: GCA_001297775_01119
symbol: GM31_12320
gene_biotype: protein_coding
description:
  Unannotated protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.


ensembl_gene_id: GCA_001297775_01124
symbol: fliA
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.


ensembl_gene_id: GCA_001297775_01127
symbol: dcyD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine; Belongs to the ACC deaminase/D-cysteine desulfhydrase family.


ensembl_gene_id: GCA_001297775_01133
symbol: uvrC
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.


ensembl_gene_id: GCA_001297775_01134
symbol: pgsA
gene_biotype: protein_coding
description:
  Unannotated protein; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.


ensembl_gene_id: GCA_001297775_01150
symbol: araG
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family.


ensembl_gene_id: GCA_001297775_01153
symbol: GM31_12540
gene_biotype: protein_coding
description:
  Unannotated protein; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.


ensembl_gene_id: GCA_001297775_01155
symbol: flhD
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.


ensembl_gene_id: GCA_001297775_01156
symbol: flhC
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family.


ensembl_gene_id: GCA_001297775_01163
symbol: GM31_12590
gene_biotype: protein_coding
description:
  Unannotated protein; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.


ensembl_gene_id: GCA_001297775_01164
symbol: cheB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.


ensembl_gene_id: GCA_001297775_01166
symbol: GM31_12605
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).


ensembl_gene_id: GCA_001297775_01171
symbol: flhB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.


ensembl_gene_id: GCA_001297775_01172
symbol: flhA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.


ensembl_gene_id: GCA_001297775_01179
symbol: cmoB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.


ensembl_gene_id: GCA_001297775_01180
symbol: cmoA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).


ensembl_gene_id: GCA_001297775_01184
symbol: aspS
gene_biotype: protein_coding
description:
  Unannotated protein; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_01187
symbol: ruvC
gene_biotype: protein_coding
description:
  Unannotated protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.


ensembl_gene_id: GCA_001297775_01188
symbol: ruvA
gene_biotype: protein_coding
description:
  Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.


ensembl_gene_id: GCA_001297775_01189
symbol: ruvB
gene_biotype: protein_coding
description:
  Unannotated protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.


ensembl_gene_id: GCA_001297775_01191
symbol: znuC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.


ensembl_gene_id: GCA_001297775_01194
symbol: lpxM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.


ensembl_gene_id: GCA_001297775_01198
symbol: edd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.


ensembl_gene_id: GCA_001297775_01200
symbol: purT
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.


ensembl_gene_id: GCA_001297775_01219
symbol: lpxP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.


ensembl_gene_id: GCA_001297775_01227
symbol: proQ
gene_biotype: protein_coding
description:
  Unannotated protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.


ensembl_gene_id: GCA_001297775_01233
symbol: mgrB
gene_biotype: protein_coding
description:
  Unannotated protein; PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.


ensembl_gene_id: GCA_001297775_01237
symbol: mntP
gene_biotype: protein_coding
description:
  Unannotated protein; Probably functions as a manganese efflux pump. Belongs to the MntP (TC 9.B.29) family.


ensembl_gene_id: GCA_001297775_01253
symbol: rnd
gene_biotype: protein_coding
description:
  Unannotated protein; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family.


ensembl_gene_id: GCA_001297775_01254
symbol: minE
gene_biotype: protein_coding
description:
  Unannotated protein; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.


ensembl_gene_id: GCA_001297775_01256
symbol: minC
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.


ensembl_gene_id: GCA_001297775_01268
symbol: dsbB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.


ensembl_gene_id: GCA_001297775_01269
symbol: nhaB
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.


ensembl_gene_id: GCA_001297775_01273
symbol: GM31_02960
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.


ensembl_gene_id: GCA_001297775_01274
symbol: cvrA
gene_biotype: protein_coding
description:
  Unannotated protein; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.


ensembl_gene_id: GCA_001297775_01276
symbol: emtA
gene_biotype: protein_coding
description:
  Unannotated protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.


ensembl_gene_id: GCA_001297775_01277
symbol: ycgR
gene_biotype: protein_coding
description:
  Unannotated protein; Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.


ensembl_gene_id: GCA_001297775_01279
symbol: treA
gene_biotype: protein_coding
description:
  Unannotated protein; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family.


ensembl_gene_id: GCA_001297775_01280
symbol: dbpA
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes.


ensembl_gene_id: GCA_001297775_01296
symbol: add
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.


ensembl_gene_id: GCA_001297775_01301
symbol: rnfA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.


ensembl_gene_id: GCA_001297775_01302
symbol: rnfB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.


ensembl_gene_id: GCA_001297775_01303
symbol: rnfC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.


ensembl_gene_id: GCA_001297775_01304
symbol: rnfD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family.


ensembl_gene_id: GCA_001297775_01305
symbol: rnfG
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family.


ensembl_gene_id: GCA_001297775_01307
symbol: nth
gene_biotype: protein_coding
description:
  Unannotated protein; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.


ensembl_gene_id: GCA_001297775_01308
symbol: tppB-2
gene_biotype: protein_coding
description:
  Unannotated protein; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily.


ensembl_gene_id: GCA_001297775_01310
symbol: tyrS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.


ensembl_gene_id: GCA_001297775_01311
symbol: pdxH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).


ensembl_gene_id: GCA_001297775_01313
symbol: anmK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.


ensembl_gene_id: GCA_001297775_01316
symbol: slyA
gene_biotype: protein_coding
description:
  Unannotated protein; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.


ensembl_gene_id: GCA_001297775_01324
symbol: GM31_16545
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.


ensembl_gene_id: GCA_001297775_01325
symbol: rnt
gene_biotype: protein_coding
description:
  Unannotated protein; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.


ensembl_gene_id: GCA_001297775_01328
symbol: GM31_16565
gene_biotype: protein_coding
description:
  Unannotated protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.


ensembl_gene_id: GCA_001297775_01331
symbol: purR
gene_biotype: protein_coding
description:
  Unannotated protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.


ensembl_gene_id: GCA_001297775_01336
symbol: mdtK
gene_biotype: protein_coding
description:
  Unannotated protein; Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.


ensembl_gene_id: GCA_001297775_01353
symbol: sufE
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family.


ensembl_gene_id: GCA_001297775_01354
symbol: sufS
gene_biotype: protein_coding
description:
  Unannotated protein; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.


ensembl_gene_id: GCA_001297775_01365
symbol: menI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA).


ensembl_gene_id: GCA_001297775_01368
symbol: GM31_13925
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.


ensembl_gene_id: GCA_001297775_01369
symbol: GM31_13930
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.


ensembl_gene_id: GCA_001297775_01370
symbol: GM31_13935
gene_biotype: protein_coding
description:
  Unannotated protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).


ensembl_gene_id: GCA_001297775_01372
symbol: selO
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family.


ensembl_gene_id: GCA_001297775_01375
symbol: btuD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_001297775_01376
symbol: btuE
gene_biotype: protein_coding
description:
  Unannotated protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent.


ensembl_gene_id: GCA_001297775_01377
symbol: btuC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.


ensembl_gene_id: GCA_001297775_01378
symbol: ihfA
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.


ensembl_gene_id: GCA_001297775_01379
symbol: pheT
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_01380
symbol: pheS
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.


ensembl_gene_id: GCA_001297775_01381
symbol: rplT
gene_biotype: protein_coding
description:
  Unannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.


ensembl_gene_id: GCA_001297775_01383
symbol: infC
gene_biotype: protein_coding
description:
  Unannotated protein; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.


ensembl_gene_id: GCA_001297775_01384
symbol: thrS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).


ensembl_gene_id: GCA_001297775_01390
symbol: GM31_14030
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.


ensembl_gene_id: GCA_001297775_01393
symbol: cls
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: GCA_001297775_01401
symbol: GM31_14085
gene_biotype: protein_coding
description:
  Unannotated protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.


ensembl_gene_id: GCA_001297775_01405
symbol: rssB
gene_biotype: protein_coding
description:
  Unannotated protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation.


ensembl_gene_id: GCA_001297775_01408
symbol: purU
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).


ensembl_gene_id: GCA_001297775_01422
symbol: GM31_03195
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.


ensembl_gene_id: GCA_001297775_01428
symbol: prmC
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.


ensembl_gene_id: GCA_001297775_01429
symbol: prfA
gene_biotype: protein_coding
description:
  Unannotated protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.


ensembl_gene_id: GCA_001297775_01430
symbol: hemA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).


ensembl_gene_id: GCA_001297775_01431
symbol: lolB
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.


ensembl_gene_id: GCA_001297775_01432
symbol: ispE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily.


ensembl_gene_id: GCA_001297775_01433
symbol: prs
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.


ensembl_gene_id: GCA_001297775_01436
symbol: pth
gene_biotype: protein_coding
description:
  Unannotated protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.


ensembl_gene_id: GCA_001297775_01437
symbol: ychF
gene_biotype: protein_coding
description:
  Unannotated protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.


ensembl_gene_id: GCA_001297775_01470
symbol: ppc
gene_biotype: protein_coding
description:
  Unannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.


ensembl_gene_id: GCA_001297775_01472
symbol: fsa
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction; Belongs to the transaldolase family. Type 3A subfamily.


ensembl_gene_id: GCA_001297775_01477
symbol: metJ
gene_biotype: protein_coding
description:
  Unannotated protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.


ensembl_gene_id: GCA_001297775_01482
symbol: priA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.


ensembl_gene_id: GCA_001297775_01484
symbol: ftsN
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.


ensembl_gene_id: GCA_001297775_01485
symbol: hslV
gene_biotype: protein_coding
description:
  Unannotated protein; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.


ensembl_gene_id: GCA_001297775_01486
symbol: hslU
gene_biotype: protein_coding
description:
  Unannotated protein; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.


ensembl_gene_id: GCA_001297775_01487
symbol: menA
gene_biotype: protein_coding
description:
  Unannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_01488
symbol: rraA
gene_biotype: protein_coding
description:
  Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.


ensembl_gene_id: GCA_001297775_01489
symbol: pfkA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.


ensembl_gene_id: GCA_001297775_01503
symbol: kdgT
gene_biotype: protein_coding
description:
  Unannotated protein; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family.


ensembl_gene_id: GCA_001297775_01505
symbol: rhaT
gene_biotype: protein_coding
description:
  Unannotated protein; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.


ensembl_gene_id: GCA_001297775_01508
symbol: rhaB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family.


ensembl_gene_id: GCA_001297775_01510
symbol: rhaD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.


ensembl_gene_id: GCA_001297775_01519
symbol: fdhD
gene_biotype: protein_coding
description:
  Unannotated protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.


ensembl_gene_id: GCA_001297775_01522
symbol: GM31_15835
gene_biotype: protein_coding
description:
  Unannotated protein; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.


ensembl_gene_id: GCA_001297775_01528
symbol: vapC
gene_biotype: protein_coding
description:
  Unannotated protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.


ensembl_gene_id: GCA_001297775_01531
symbol: dtd
gene_biotype: protein_coding
description:
  Unannotated protein; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.


ensembl_gene_id: GCA_001297775_01539
symbol: glnG
gene_biotype: protein_coding
description:
  Unannotated protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.


ensembl_gene_id: GCA_001297775_01542
symbol: yihI
gene_biotype: protein_coding
description:
  Unannotated protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family.


ensembl_gene_id: GCA_001297775_01543
symbol: engB
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.


ensembl_gene_id: GCA_001297775_01544
symbol: polA
gene_biotype: protein_coding
description:
  Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.


ensembl_gene_id: GCA_001297775_01547
symbol: srkA
gene_biotype: protein_coding
description:
  Unannotated protein; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.


ensembl_gene_id: GCA_001297775_01549
symbol: mobA
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.


ensembl_gene_id: GCA_001297775_01556
symbol: hdfR
gene_biotype: protein_coding
description:
  Unannotated protein; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.


ensembl_gene_id: GCA_001297775_01561
symbol: ilvE
gene_biotype: protein_coding
description:
  Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.


ensembl_gene_id: GCA_001297775_01563
symbol: ilvA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.


ensembl_gene_id: GCA_001297775_01566
symbol: ilvC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.


ensembl_gene_id: GCA_001297775_01571
symbol: rep
gene_biotype: protein_coding
description:
  Unannotated protein; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.


ensembl_gene_id: GCA_001297775_01572
symbol: gppA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.


ensembl_gene_id: GCA_001297775_01573
symbol: rhlB
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.


ensembl_gene_id: GCA_001297775_01575
symbol: rho
gene_biotype: protein_coding
description:
  Unannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.


ensembl_gene_id: GCA_001297775_01576
symbol: wecA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).


ensembl_gene_id: GCA_001297775_01577
symbol: wzzE
gene_biotype: protein_coding
description:
  Unannotated protein; Modulates the polysaccharide chain length of enterobacterial common antigen (ECA); Belongs to the WzzB/Cld/Rol family.


ensembl_gene_id: GCA_001297775_01578
symbol: wecB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.


ensembl_gene_id: GCA_001297775_01579
symbol: wecC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.


ensembl_gene_id: GCA_001297775_01580
symbol: GM31_12010
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.


ensembl_gene_id: GCA_001297775_01581
symbol: GM31_12015
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.


ensembl_gene_id: GCA_001297775_01582
symbol: wecD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family.


ensembl_gene_id: GCA_001297775_01583
symbol: wecE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family.


ensembl_gene_id: GCA_001297775_01584
symbol: wzxE
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA); Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.


ensembl_gene_id: GCA_001297775_01585
symbol: wecF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family.


ensembl_gene_id: GCA_001297775_01586
symbol: wzyE
gene_biotype: protein_coding
description:
  Unannotated protein; Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units; Belongs to the WzyE family.


ensembl_gene_id: GCA_001297775_01587
symbol: wecG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.


ensembl_gene_id: GCA_001297775_01595
symbol: hemD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.


ensembl_gene_id: GCA_001297775_01596
symbol: hemC
gene_biotype: protein_coding
description:
  Unannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.


ensembl_gene_id: GCA_001297775_01598
symbol: cyaY
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.


ensembl_gene_id: GCA_001297775_01600
symbol: dapF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.


ensembl_gene_id: GCA_001297775_01602
symbol: xerC
gene_biotype: protein_coding
description:
  Unannotated protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top [...]


ensembl_gene_id: GCA_001297775_01605
symbol: corA
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates influx of magnesium ions. Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: GCA_001297775_01608
symbol: GM31_22430
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family.


ensembl_gene_id: GCA_001297775_01616
symbol: metE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.


ensembl_gene_id: GCA_001297775_01618
symbol: GM31_10120
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.


ensembl_gene_id: GCA_001297775_01620
symbol: ubiE
gene_biotype: protein_coding
description:
  Unannotated protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).


ensembl_gene_id: GCA_001297775_01622
symbol: ubiB
gene_biotype: protein_coding
description:
  Unannotated protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.


ensembl_gene_id: GCA_001297775_01623
symbol: tatA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.


ensembl_gene_id: GCA_001297775_01624
symbol: tatB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.


ensembl_gene_id: GCA_001297775_01625
symbol: tatC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.


ensembl_gene_id: GCA_001297775_01626
symbol: tatD
gene_biotype: protein_coding
description:
  Unannotated protein; 3'-5' exonuclease that prefers single-stranded DNA and RNA. May play a role in the H(2)O(2)-induced DNA damage repair. Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.


ensembl_gene_id: GCA_001297775_01627
symbol: rfaH
gene_biotype: protein_coding
description:
  Unannotated protein; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.


ensembl_gene_id: GCA_001297775_01628
symbol: ubiD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.


ensembl_gene_id: GCA_001297775_01630
symbol: fadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.


ensembl_gene_id: GCA_001297775_01631
symbol: fadB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: GCA_001297775_01634
symbol: GM31_10200
gene_biotype: protein_coding
description:
  Unannotated protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.


ensembl_gene_id: GCA_001297775_01638
symbol: tal
gene_biotype: protein_coding
description:
  Unannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.


ensembl_gene_id: GCA_001297775_01673
symbol: gltS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.


ensembl_gene_id: GCA_001297775_01674
symbol: glpK
gene_biotype: protein_coding
description:
  Unannotated protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.


ensembl_gene_id: GCA_001297775_01681
symbol: GM31_07130
gene_biotype: protein_coding
description:
  Unannotated protein; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.


ensembl_gene_id: GCA_001297775_01695
symbol: rpsJ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.


ensembl_gene_id: GCA_001297775_01696
symbol: rplC
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.


ensembl_gene_id: GCA_001297775_01698
symbol: rplW
gene_biotype: protein_coding
description:
  Unannotated protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.


ensembl_gene_id: GCA_001297775_01699
symbol: rplB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.


ensembl_gene_id: GCA_001297775_01700
symbol: rpsS
gene_biotype: protein_coding
description:
  Unannotated protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.


ensembl_gene_id: GCA_001297775_01701
symbol: rplV
gene_biotype: protein_coding
description:
  Unannotated protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.


ensembl_gene_id: GCA_001297775_01702
symbol: rpsC
gene_biotype: protein_coding
description:
  Unannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.


ensembl_gene_id: GCA_001297775_01703
symbol: rplP
gene_biotype: protein_coding
description:
  Unannotated protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.


ensembl_gene_id: GCA_001297775_01705
symbol: rpsQ
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.


ensembl_gene_id: GCA_001297775_01706
symbol: rplN
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.


ensembl_gene_id: GCA_001297775_01707
symbol: rplX
gene_biotype: protein_coding
description:
  Unannotated protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.


ensembl_gene_id: GCA_001297775_01708
symbol: rplE
gene_biotype: protein_coding
description:
  Unannotated protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.


ensembl_gene_id: GCA_001297775_01709
symbol: rpsN
gene_biotype: protein_coding
description:
  Unannotated protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family.


ensembl_gene_id: GCA_001297775_01710
symbol: rpsH
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.


ensembl_gene_id: GCA_001297775_01711
symbol: rplF
gene_biotype: protein_coding
description:
  Unannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.


ensembl_gene_id: GCA_001297775_01712
symbol: rplR
gene_biotype: protein_coding
description:
  Unannotated protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.


ensembl_gene_id: GCA_001297775_01713
symbol: rpsE
gene_biotype: protein_coding
description:
  Unannotated protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.


ensembl_gene_id: GCA_001297775_01716
symbol: secY
gene_biotype: protein_coding
description:
  Unannotated protein; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.


ensembl_gene_id: GCA_001297775_01718
symbol: rpsM
gene_biotype: protein_coding
description:
  Unannotated protein; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.


ensembl_gene_id: GCA_001297775_01719
symbol: rpsD
gene_biotype: protein_coding
description:
  Unannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.


ensembl_gene_id: GCA_001297775_01720
symbol: rpoA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.


ensembl_gene_id: GCA_001297775_01725
symbol: mscL
gene_biotype: protein_coding
description:
  Unannotated protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.


ensembl_gene_id: GCA_001297775_01728
symbol: fmt
gene_biotype: protein_coding
description:
  Unannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.


ensembl_gene_id: GCA_001297775_01729
symbol: def
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.


ensembl_gene_id: GCA_001297775_01733
symbol: tsaC
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.


ensembl_gene_id: GCA_001297775_01734
symbol: aroE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).


ensembl_gene_id: GCA_001297775_01786
symbol: zapB
gene_biotype: protein_coding
description:
  Unannotated protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.


ensembl_gene_id: GCA_001297775_01787
symbol: trmA
gene_biotype: protein_coding
description:
  Unannotated protein; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).


ensembl_gene_id: GCA_001297775_01788
symbol: btuB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.


ensembl_gene_id: GCA_001297775_01798
symbol: pyrB
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.


ensembl_gene_id: GCA_001297775_01801
symbol: GM31_19650
gene_biotype: protein_coding
description:
  Unannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.


ensembl_gene_id: GCA_001297775_01806
symbol: rraB
gene_biotype: protein_coding
description:
  Unannotated protein; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.


ensembl_gene_id: GCA_001297775_01810
symbol: valS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.


ensembl_gene_id: GCA_001297775_01812
symbol: pepA
gene_biotype: protein_coding
description:
  Unannotated protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.


ensembl_gene_id: GCA_001297775_01825
symbol: diaA
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein. Belongs to the SIS family. DiaA subfamily.


ensembl_gene_id: GCA_001297775_01827
symbol: lpoA
gene_biotype: protein_coding
description:
  Unannotated protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.


ensembl_gene_id: GCA_001297775_01828
symbol: rsmI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.


ensembl_gene_id: GCA_001297775_01842
symbol: garD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate.


ensembl_gene_id: GCA_001297775_01844
symbol: garL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible retro-aldol cleavage of both 5-keto- 4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde; Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.


ensembl_gene_id: GCA_001297775_01845
symbol: garR
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily.


ensembl_gene_id: GCA_001297775_01849
symbol: tdcC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.


ensembl_gene_id: GCA_001297775_01867
symbol: mzrA
gene_biotype: protein_coding
description:
  Unannotated protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.


ensembl_gene_id: GCA_001297775_01873
symbol: sstT
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: GCA_001297775_01881
symbol: lsrK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.


ensembl_gene_id: GCA_001297775_01887
symbol: lsrF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family.


ensembl_gene_id: GCA_001297775_01888
symbol: lsrG
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.


ensembl_gene_id: GCA_001297775_01902
symbol: GM31_08365
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.


ensembl_gene_id: GCA_001297775_01918
symbol: dnaT
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.


ensembl_gene_id: GCA_001297775_01933
symbol: rsmC
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family.


ensembl_gene_id: GCA_001297775_01934
symbol: GM31_11870
gene_biotype: protein_coding
description:
  Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.


ensembl_gene_id: GCA_001297775_01937
symbol: prfC
gene_biotype: protein_coding
description:
  Unannotated protein; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.


ensembl_gene_id: GCA_001297775_01945
symbol: deoC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.


ensembl_gene_id: GCA_001297775_01946
symbol: deoA
gene_biotype: protein_coding
description:
  Unannotated protein; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.


ensembl_gene_id: GCA_001297775_01947
symbol: deoB
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.


ensembl_gene_id: GCA_001297775_01949
symbol: lplA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family.


ensembl_gene_id: GCA_001297775_01952
symbol: radA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.


ensembl_gene_id: GCA_001297775_01956
symbol: trpR
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.


ensembl_gene_id: GCA_001297775_01957
symbol: yjjX
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.


ensembl_gene_id: GCA_001297775_01968
symbol: thrB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.


ensembl_gene_id: GCA_001297775_01977
symbol: dnaJ
gene_biotype: protein_coding
description:
  Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]


ensembl_gene_id: GCA_001297775_01980
symbol: nhaA
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.


ensembl_gene_id: GCA_001297775_01984
symbol: ileS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.


ensembl_gene_id: GCA_001297775_01985
symbol: lspA
gene_biotype: protein_coding
description:
  Unannotated protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.


ensembl_gene_id: GCA_001297775_01987
symbol: ispH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.


ensembl_gene_id: GCA_001297775_01996
symbol: dapB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.


ensembl_gene_id: GCA_001297775_02002
symbol: folA
gene_biotype: protein_coding
description:
  Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


ensembl_gene_id: GCA_001297775_02003
symbol: apaH
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.


ensembl_gene_id: GCA_001297775_02005
symbol: ksgA
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.


ensembl_gene_id: GCA_001297775_02006
symbol: pdxA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).


ensembl_gene_id: GCA_001297775_02007
symbol: surA
gene_biotype: protein_coding
description:
  Unannotated protein; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.


ensembl_gene_id: GCA_001297775_02008
symbol: lptD
gene_biotype: protein_coding
description:
  Unannotated protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.


ensembl_gene_id: GCA_001297775_02009
symbol: djlA
gene_biotype: protein_coding
description:
  Unannotated protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.


ensembl_gene_id: GCA_001297775_02010
symbol: GM31_15395
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.


ensembl_gene_id: GCA_001297775_02011
symbol: rapA
gene_biotype: protein_coding
description:
  Unannotated protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.


ensembl_gene_id: GCA_001297775_02013
symbol: araD
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).


ensembl_gene_id: GCA_001297775_02018
symbol: thiQ
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.


ensembl_gene_id: GCA_001297775_02024
symbol: leuD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.


ensembl_gene_id: GCA_001297775_02025
symbol: leuC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.


ensembl_gene_id: GCA_001297775_02026
symbol: leuB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.


ensembl_gene_id: GCA_001297775_02027
symbol: leuA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.


ensembl_gene_id: GCA_001297775_02032
symbol: mraZ
gene_biotype: protein_coding
description:
  Unannotated protein; Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.


ensembl_gene_id: GCA_001297775_02033
symbol: rsmH
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.


ensembl_gene_id: GCA_001297775_02034
symbol: ftsL
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.


ensembl_gene_id: GCA_001297775_02035
symbol: ftsI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.


ensembl_gene_id: GCA_001297775_02036
symbol: murE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.


ensembl_gene_id: GCA_001297775_02037
symbol: murF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.


ensembl_gene_id: GCA_001297775_02038
symbol: mraY
gene_biotype: protein_coding
description:
  Unannotated protein; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.


ensembl_gene_id: GCA_001297775_02039
symbol: murD
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.


ensembl_gene_id: GCA_001297775_02040
symbol: ftsW
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.


ensembl_gene_id: GCA_001297775_02041
symbol: murG
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.


ensembl_gene_id: GCA_001297775_02044
symbol: ftsQ
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.


ensembl_gene_id: GCA_001297775_02045
symbol: ftsA
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.


ensembl_gene_id: GCA_001297775_02046
symbol: ftsZ
gene_biotype: protein_coding
description:
  Unannotated protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.


ensembl_gene_id: GCA_001297775_02047
symbol: lpxC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.


ensembl_gene_id: GCA_001297775_02048
symbol: secM
gene_biotype: protein_coding
description:
  Unannotated protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.


ensembl_gene_id: GCA_001297775_02049
symbol: secA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.


ensembl_gene_id: GCA_001297775_02051
symbol: yacG
gene_biotype: protein_coding
description:
  Unannotated protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.


ensembl_gene_id: GCA_001297775_02052
symbol: zapD
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.


ensembl_gene_id: GCA_001297775_02053
symbol: coaE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.


ensembl_gene_id: GCA_001297775_02054
symbol: guaC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.


ensembl_gene_id: GCA_001297775_02065
symbol: aceE
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).


ensembl_gene_id: GCA_001297775_02077
symbol: speD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.


ensembl_gene_id: GCA_001297775_02078
symbol: speE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.


ensembl_gene_id: GCA_001297775_02083
symbol: GM31_12080
gene_biotype: protein_coding
description:
  Unannotated protein; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.


ensembl_gene_id: GCA_001297775_02088
symbol: panD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.


ensembl_gene_id: GCA_001297775_02089
symbol: panC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.


ensembl_gene_id: GCA_001297775_02090
symbol: panB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.


ensembl_gene_id: GCA_001297775_02092
symbol: pcnB
gene_biotype: protein_coding
description:
  Unannotated protein; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.


ensembl_gene_id: GCA_001297775_02093
symbol: gluQ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.


ensembl_gene_id: GCA_001297775_02094
symbol: dksA
gene_biotype: protein_coding
description:
  Unannotated protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.


ensembl_gene_id: GCA_001297775_02096
symbol: GM31_12145
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.


ensembl_gene_id: GCA_001297775_02098
symbol: mrcB
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).


ensembl_gene_id: GCA_001297775_02102
symbol: GM31_20445
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.


ensembl_gene_id: GCA_001297775_02104
symbol: clcA
gene_biotype: protein_coding
description:
  Unannotated protein; Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response. Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.


ensembl_gene_id: GCA_001297775_02107
symbol: btuF
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.


ensembl_gene_id: GCA_001297775_02108
symbol: mtnN
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation. Belongs to the PNP/UDP phosphorylase [...]


ensembl_gene_id: GCA_001297775_02109
symbol: dgt
gene_biotype: protein_coding
description:
  Unannotated protein; dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs; Belongs to the dGTPase family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_02114
symbol: glnD
gene_biotype: protein_coding
description:
  Unannotated protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.


ensembl_gene_id: GCA_001297775_02115
symbol: map
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.


ensembl_gene_id: GCA_001297775_02117
symbol: tsf
gene_biotype: protein_coding
description:
  Unannotated protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.


ensembl_gene_id: GCA_001297775_02119
symbol: frr
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.


ensembl_gene_id: GCA_001297775_02120
symbol: dxr
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP).


ensembl_gene_id: GCA_001297775_02121
symbol: uppS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.


ensembl_gene_id: GCA_001297775_02124
symbol: bamA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.


ensembl_gene_id: GCA_001297775_02126
symbol: lpxD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily.


ensembl_gene_id: GCA_001297775_02127
symbol: fabZ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.


ensembl_gene_id: GCA_001297775_02128
symbol: lpxA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.


ensembl_gene_id: GCA_001297775_02132
symbol: accA
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.


ensembl_gene_id: GCA_001297775_02135
symbol: tilS
gene_biotype: protein_coding
description:
  Unannotated protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.


ensembl_gene_id: GCA_001297775_02141
symbol: proS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacyl [...]


ensembl_gene_id: GCA_001297775_02143
symbol: rcsF
gene_biotype: protein_coding
description:
  Unannotated protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.


ensembl_gene_id: GCA_001297775_02146
symbol: metN
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_001297775_02150
symbol: secE
gene_biotype: protein_coding
description:
  Unannotated protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family.


ensembl_gene_id: GCA_001297775_02151
symbol: nusG
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs to the NusG family.


ensembl_gene_id: GCA_001297775_02152
symbol: rplK
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.


ensembl_gene_id: GCA_001297775_02153
symbol: rplA
gene_biotype: protein_coding
description:
  Unannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.


ensembl_gene_id: GCA_001297775_02154
symbol: rplJ
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.


ensembl_gene_id: GCA_001297775_02155
symbol: rplL
gene_biotype: protein_coding
description:
  Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.


ensembl_gene_id: GCA_001297775_02161
symbol: thiG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.


ensembl_gene_id: GCA_001297775_02164
symbol: thiE
gene_biotype: protein_coding
description:
  Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.


ensembl_gene_id: GCA_001297775_02165
symbol: thiC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.


ensembl_gene_id: GCA_001297775_02166
symbol: rsd
gene_biotype: protein_coding
description:
  Unannotated protein; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.


ensembl_gene_id: GCA_001297775_02168
symbol: hemE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.


ensembl_gene_id: GCA_001297775_02169
symbol: nfi
gene_biotype: protein_coding
description:
  Unannotated protein; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.


ensembl_gene_id: GCA_001297775_02173
symbol: zraP
gene_biotype: protein_coding
description:
  Unannotated protein; Binds zinc. Could be an important component of the zinc- balancing mechanism; Belongs to the ZraP family.


ensembl_gene_id: GCA_001297775_02186
symbol: GM31_05875
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.


ensembl_gene_id: GCA_001297775_02188
symbol: gapA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.


ensembl_gene_id: GCA_001297775_02204
symbol: birA
gene_biotype: protein_coding
description:
  Unannotated protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.


ensembl_gene_id: GCA_001297775_02229
symbol: argO
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine; Belongs to the LysE/ArgO transporter (TC 2.A.75) family.


ensembl_gene_id: GCA_001297775_02231
symbol: argP
gene_biotype: protein_coding
description:
  Unannotated protein; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family.


ensembl_gene_id: GCA_001297775_02232
symbol: rpiA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.


ensembl_gene_id: GCA_001297775_02236
symbol: zapA
gene_biotype: protein_coding
description:
  Unannotated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.


ensembl_gene_id: GCA_001297775_02242
symbol: gcvH
gene_biotype: protein_coding
description:
  Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.


ensembl_gene_id: GCA_001297775_02243
symbol: gcvP
gene_biotype: protein_coding
description:
  Unannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.


ensembl_gene_id: GCA_001297775_02245
symbol: ygfZ
gene_biotype: protein_coding
description:
  Unannotated protein; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family.


ensembl_gene_id: GCA_001297775_02248
symbol: GM31_06005
gene_biotype: protein_coding
description:
  Unannotated protein; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.


ensembl_gene_id: GCA_001297775_02249
symbol: xerD
gene_biotype: protein_coding
description:
  Unannotated protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bot [...]


ensembl_gene_id: GCA_001297775_02250
symbol: GM31_06015
gene_biotype: protein_coding
description:
  Unannotated protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.


ensembl_gene_id: GCA_001297775_02252
symbol: prfB
gene_biotype: protein_coding
description:
  Unannotated protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.


ensembl_gene_id: GCA_001297775_02287
symbol: fbpC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_001297775_02332
symbol: kduI
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.


ensembl_gene_id: GCA_001297775_02337
symbol: lysA
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.


ensembl_gene_id: GCA_001297775_02341
symbol: GM31_10540
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.


ensembl_gene_id: GCA_001297775_02342
symbol: lplT
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell; Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.


ensembl_gene_id: GCA_001297775_02346
symbol: mutH
gene_biotype: protein_coding
description:
  Unannotated protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.


ensembl_gene_id: GCA_001297775_02347
symbol: rppH
gene_biotype: protein_coding
description:
  Unannotated protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.


ensembl_gene_id: GCA_001297775_02349
symbol: lgt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.


ensembl_gene_id: GCA_001297775_02350
symbol: thyA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.


ensembl_gene_id: GCA_001297775_02355
symbol: recC
gene_biotype: protein_coding
description:
  Unannotated protein; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme  [...]


ensembl_gene_id: GCA_001297775_02363
symbol: mltA
gene_biotype: protein_coding
description:
  Unannotated protein; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.


ensembl_gene_id: GCA_001297775_02370
symbol: rlmM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.


ensembl_gene_id: GCA_001297775_02371
symbol: xni
gene_biotype: protein_coding
description:
  Unannotated protein; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.


ensembl_gene_id: GCA_001297775_02375
symbol: queF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).


ensembl_gene_id: GCA_001297775_02376
symbol: syd
gene_biotype: protein_coding
description:
  Unannotated protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.


ensembl_gene_id: GCA_001297775_02385
symbol: rumA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.


ensembl_gene_id: GCA_001297775_02389
symbol: pyrG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.


ensembl_gene_id: GCA_001297775_02390
symbol: eno
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.


ensembl_gene_id: GCA_001297775_02392
symbol: nanE
gene_biotype: protein_coding
description:
  Unannotated protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).


ensembl_gene_id: GCA_001297775_02393
symbol: queE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.


ensembl_gene_id: GCA_001297775_02395
symbol: cysJ
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family.


ensembl_gene_id: GCA_001297775_02396
symbol: cysI
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.


ensembl_gene_id: GCA_001297775_02397
symbol: cysH
gene_biotype: protein_coding
description:
  Unannotated protein; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.


ensembl_gene_id: GCA_001297775_02400
symbol: cysN
gene_biotype: protein_coding
description:
  Unannotated protein; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.


ensembl_gene_id: GCA_001297775_02404
symbol: ispD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.


ensembl_gene_id: GCA_001297775_02405
symbol: ispF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).


ensembl_gene_id: GCA_001297775_02406
symbol: truD
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.


ensembl_gene_id: GCA_001297775_02407
symbol: surE
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.


ensembl_gene_id: GCA_001297775_02408
symbol: pcm
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.


ensembl_gene_id: GCA_001297775_02410
symbol: rpoS
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.


ensembl_gene_id: GCA_001297775_02411
symbol: mutS
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.


ensembl_gene_id: GCA_001297775_02420
symbol: hypA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.


ensembl_gene_id: GCA_001297775_02450
symbol: recA
gene_biotype: protein_coding
description:
  Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.


ensembl_gene_id: GCA_001297775_02452
symbol: alaS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family.


ensembl_gene_id: GCA_001297775_02453
symbol: csrA
gene_biotype: protein_coding
description:
  Unannotated protein; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).


ensembl_gene_id: GCA_001297775_02463
symbol: luxS
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.


ensembl_gene_id: GCA_001297775_02474
symbol: GM31_10910
gene_biotype: protein_coding
description:
  Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.


ensembl_gene_id: GCA_001297775_02592
symbol: smpB
gene_biotype: protein_coding
description:
  Unannotated protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to  [...]


ensembl_gene_id: GCA_001297775_02597
symbol: ppnK
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.


ensembl_gene_id: GCA_001297775_02598
symbol: grpE
gene_biotype: protein_coding
description:
  Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]


ensembl_gene_id: GCA_001297775_02601
symbol: ffh
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to t [...]


ensembl_gene_id: GCA_001297775_02603
symbol: rimM
gene_biotype: protein_coding
description:
  Unannotated protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.


ensembl_gene_id: GCA_001297775_02604
symbol: trmD
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.


ensembl_gene_id: GCA_001297775_02605
symbol: rplS
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.


ensembl_gene_id: GCA_001297775_02613
symbol: bamD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery.


ensembl_gene_id: GCA_001297775_02616
symbol: clpB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.


ensembl_gene_id: GCA_001297775_02688
symbol: putA
gene_biotype: protein_coding
description:
  Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family.  In the N-terminal section; belongs to the proline dehydrogenase family.


ensembl_gene_id: GCA_001297775_02689
symbol: GM31_19420
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: GCA_001297775_02692
symbol: GM31_19435
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family.


ensembl_gene_id: GCA_001297775_02701
symbol: ghrA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.


ensembl_gene_id: GCA_001297775_02713
symbol: opgC
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.


ensembl_gene_id: GCA_001297775_02718
symbol: lpxL
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).


ensembl_gene_id: GCA_001297775_02720
symbol: solA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidative demethylation of N-methyl-L- tryptophan; Belongs to the MSOX/MTOX family. MTOX subfamily.


ensembl_gene_id: GCA_001297775_02729
symbol: murJ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.


ensembl_gene_id: GCA_001297775_02732
symbol: flgA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family.


ensembl_gene_id: GCA_001297775_02733
symbol: GM31_18555
gene_biotype: protein_coding
description:
  Unannotated protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.


ensembl_gene_id: GCA_001297775_02739
symbol: flgH
gene_biotype: protein_coding
description:
  Unannotated protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.


ensembl_gene_id: GCA_001297775_02746
symbol: rne
gene_biotype: protein_coding
description:
  Unannotated protein; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily.


ensembl_gene_id: GCA_001297775_02748
symbol: GM31_18630
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily.


ensembl_gene_id: GCA_001297775_02751
symbol: plsX
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.


ensembl_gene_id: GCA_001297775_02752
symbol: fabH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.


ensembl_gene_id: GCA_001297775_02754
symbol: fabG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.


ensembl_gene_id: GCA_001297775_02756
symbol: GM31_18675
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.


ensembl_gene_id: GCA_001297775_02758
symbol: mltG
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.


ensembl_gene_id: GCA_001297775_02759
symbol: tmk
gene_biotype: protein_coding
description:
  Unannotated protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.


ensembl_gene_id: GCA_001297775_02766
symbol: lpoB
gene_biotype: protein_coding
description:
  Unannotated protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b). Belongs to the LpoB family.


ensembl_gene_id: GCA_001297775_02768
symbol: nagZ
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.


ensembl_gene_id: GCA_001297775_02775
symbol: mfd
gene_biotype: protein_coding
description:
  Unannotated protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.


ensembl_gene_id: GCA_001297775_02778
symbol: lolD
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.


ensembl_gene_id: GCA_001297775_02780
symbol: nagK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.


ensembl_gene_id: GCA_001297775_02785
symbol: potA-2
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.


ensembl_gene_id: GCA_001297775_02786
symbol: pepT
gene_biotype: protein_coding
description:
  Unannotated protein; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.


ensembl_gene_id: GCA_001297775_02793
symbol: mnmA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family.


ensembl_gene_id: GCA_001297775_02899
symbol: topB
gene_biotype: protein_coding
description:
  Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]


ensembl_gene_id: GCA_001297775_02912
symbol: astA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.


ensembl_gene_id: GCA_001297775_02913
symbol: astD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.


ensembl_gene_id: GCA_001297775_02914
symbol: astB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).


ensembl_gene_id: GCA_001297775_02915
symbol: astE
gene_biotype: protein_coding
description:
  Unannotated protein; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.


ensembl_gene_id: GCA_001297775_02925
symbol: nadE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.


ensembl_gene_id: GCA_001297775_02932
symbol: chbG
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, th [...]


ensembl_gene_id: GCA_001297775_02940
symbol: GM31_09820
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.


ensembl_gene_id: GCA_001297775_02945
symbol: trpA
gene_biotype: protein_coding
description:
  Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.


ensembl_gene_id: GCA_001297775_02946
symbol: trpB
gene_biotype: protein_coding
description:
  Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.


ensembl_gene_id: GCA_001297775_02948
symbol: trpD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).


ensembl_gene_id: GCA_001297775_02959
symbol: GM31_09915
gene_biotype: protein_coding
description:
  Unannotated protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.


ensembl_gene_id: GCA_001297775_02967
symbol: ribA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.


ensembl_gene_id: GCA_001297775_02969
symbol: lapA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family.


ensembl_gene_id: GCA_001297775_02970
symbol: lapB
gene_biotype: protein_coding
description:
  Unannotated protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.


ensembl_gene_id: GCA_001297775_02971
symbol: pyrF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_02977
symbol: rnb
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.


ensembl_gene_id: GCA_001297775_03008
symbol: fis
gene_biotype: protein_coding
description:
  Unannotated protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family.


ensembl_gene_id: GCA_001297775_03009
symbol: dusB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily.


ensembl_gene_id: GCA_001297775_03010
symbol: prmA
gene_biotype: protein_coding
description:
  Unannotated protein; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.


ensembl_gene_id: GCA_001297775_03020
symbol: GM31_17405
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.


ensembl_gene_id: GCA_001297775_03023
symbol: msrQ
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the  [...]


ensembl_gene_id: GCA_001297775_03024
symbol: msrP
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) [...]


ensembl_gene_id: GCA_001297775_03029
symbol: GM31_17360
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.


ensembl_gene_id: GCA_001297775_03030
symbol: GM31_17355
gene_biotype: protein_coding
description:
  Unannotated protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.


ensembl_gene_id: GCA_001297775_03036
symbol: aaeA
gene_biotype: protein_coding
description:
  Unannotated protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.


ensembl_gene_id: GCA_001297775_03037
symbol: aaeB
gene_biotype: protein_coding
description:
  Unannotated protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.


ensembl_gene_id: GCA_001297775_03048
symbol: rplM
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.


ensembl_gene_id: GCA_001297775_03052
symbol: nanR
gene_biotype: protein_coding
description:
  Unannotated protein; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids.


ensembl_gene_id: GCA_001297775_03053
symbol: nanA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.


ensembl_gene_id: GCA_001297775_03054
symbol: nanT
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.


ensembl_gene_id: GCA_001297775_03061
symbol: GM31_17195
gene_biotype: protein_coding
description:
  Unannotated protein; Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate; Belongs to the peptidase C56 family.


ensembl_gene_id: GCA_001297775_03062
symbol: mtgA
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.


ensembl_gene_id: GCA_001297775_03064
symbol: rapZ
gene_biotype: protein_coding
description:
  Unannotated protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.


ensembl_gene_id: GCA_001297775_03067
symbol: GM31_17165
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.


ensembl_gene_id: GCA_001297775_03069
symbol: lptA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.


ensembl_gene_id: GCA_001297775_03070
symbol: lptC
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.


ensembl_gene_id: GCA_001297775_03071
symbol: GM31_17145
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.


ensembl_gene_id: GCA_001297775_03080
symbol: murA
gene_biotype: protein_coding
description:
  Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.


ensembl_gene_id: GCA_001297775_03083
symbol: rplU
gene_biotype: protein_coding
description:
  Unannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.


ensembl_gene_id: GCA_001297775_03086
symbol: obgE
gene_biotype: protein_coding
description:
  Unannotated protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.


ensembl_gene_id: GCA_001297775_03088
symbol: greA
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.


ensembl_gene_id: GCA_001297775_03090
symbol: rrmJ
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.


ensembl_gene_id: GCA_001297775_03091
symbol: hflB
gene_biotype: protein_coding
description:
  Unannotated protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family.  In the central section; belongs to the AAA ATPase family.


ensembl_gene_id: GCA_001297775_03092
symbol: folP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.


ensembl_gene_id: GCA_001297775_03093
symbol: glmM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.


ensembl_gene_id: GCA_001297775_03094
symbol: secG
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.


ensembl_gene_id: GCA_001297775_03103
symbol: infB
gene_biotype: protein_coding
description:
  Unannotated protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.


ensembl_gene_id: GCA_001297775_03104
symbol: rbfA
gene_biotype: protein_coding
description:
  Unannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.


ensembl_gene_id: GCA_001297775_03105
symbol: truB
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_03106
symbol: rpsO
gene_biotype: protein_coding
description:
  Unannotated protein; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.


ensembl_gene_id: GCA_001297775_03107
symbol: pnp
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.


ensembl_gene_id: GCA_001297775_03109
symbol: deaD
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.


ensembl_gene_id: GCA_001297775_03115
symbol: cpdA
gene_biotype: protein_coding
description:
  Unannotated protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.


ensembl_gene_id: GCA_001297775_03160
symbol: GM31_23085
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.


ensembl_gene_id: GCA_001297775_03183
symbol: GM31_22655
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.


ensembl_gene_id: GCA_001297775_03193
symbol: hyuA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'- position. Has no activity on dihydropyrimidines. The physiological function is unknown; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.


ensembl_gene_id: GCA_001297775_03213
symbol: GM31_02300
gene_biotype: protein_coding
description:
  Unannotated protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.


ensembl_gene_id: GCA_001297775_03216
symbol: patA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.


ensembl_gene_id: GCA_001297775_03235
symbol: mug
gene_biotype: protein_coding
description:
  Unannotated protein; Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells; Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.


ensembl_gene_id: GCA_001297775_03236
symbol: rpoD
gene_biotype: protein_coding
description:
  Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.


ensembl_gene_id: GCA_001297775_03237
symbol: dnaG
gene_biotype: protein_coding
description:
  Unannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.


ensembl_gene_id: GCA_001297775_03239
symbol: tsaD
gene_biotype: protein_coding
description:
  Unannotated protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.


ensembl_gene_id: GCA_001297775_03240
symbol: plsY
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.


ensembl_gene_id: GCA_001297775_03241
symbol: folB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.


ensembl_gene_id: GCA_001297775_03242
symbol: uppP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.


ensembl_gene_id: GCA_001297775_03243
symbol: cca
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.


ensembl_gene_id: GCA_001297775_03246
symbol: glnE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) [...]


ensembl_gene_id: GCA_001297775_03247
symbol: hldE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.


ensembl_gene_id: GCA_001297775_03248
symbol: glgS
gene_biotype: protein_coding
description:
  Unannotated protein; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.


ensembl_gene_id: GCA_001297775_03250
symbol: ribB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.


ensembl_gene_id: GCA_001297775_03255
symbol: zupT
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.


ensembl_gene_id: GCA_001297775_03264
symbol: parE
gene_biotype: protein_coding
description:
  Unannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.


ensembl_gene_id: GCA_001297775_03270
symbol: parC
gene_biotype: protein_coding
description:
  Unannotated protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.


ensembl_gene_id: GCA_001297775_03272
symbol: ftsP
gene_biotype: protein_coding
description:
  Unannotated protein; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress; Belongs to the FtsP family.


ensembl_gene_id: GCA_001297775_03311
symbol: GM31_13375
gene_biotype: protein_coding
description:
  Unannotated protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes; Belongs to the Fe(2+)-trafficking protein family.


ensembl_gene_id: GCA_001297775_03313
symbol: trmB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.


ensembl_gene_id: GCA_001297775_03317
symbol: GM31_13345
gene_biotype: protein_coding
description:
  Unannotated protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.


ensembl_gene_id: GCA_001297775_03318
symbol: GM31_13340
gene_biotype: protein_coding
description:
  Unannotated protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.


ensembl_gene_id: GCA_001297775_03321
symbol: GM31_13325
gene_biotype: protein_coding
description:
  Unannotated protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.


ensembl_gene_id: GCA_001297775_03324
symbol: yqgF
gene_biotype: protein_coding
description:
  Unannotated protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.


ensembl_gene_id: GCA_001297775_03327
symbol: GM31_13295
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.


ensembl_gene_id: GCA_001297775_03331
symbol: metK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.


ensembl_gene_id: GCA_001297775_03333
symbol: speB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.


ensembl_gene_id: GCA_001297775_03339
symbol: GM31_16035
gene_biotype: protein_coding
description:
  Unannotated protein; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.


ensembl_gene_id: GCA_001297775_03344
symbol: hspQ
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family.


ensembl_gene_id: GCA_001297775_03352
symbol: sulA
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.


ensembl_gene_id: GCA_001297775_03354
symbol: matP
gene_biotype: protein_coding
description:
  Unannotated protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.


ensembl_gene_id: GCA_001297775_03356
symbol: fabA
gene_biotype: protein_coding
description:
  Unannotated protein; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.


ensembl_gene_id: GCA_001297775_03361
symbol: rlmL
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.


ensembl_gene_id: GCA_001297775_03363
symbol: zapC
gene_biotype: protein_coding
description:
  Unannotated protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.


ensembl_gene_id: GCA_001297775_03364
symbol: pyrD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.


ensembl_gene_id: GCA_001297775_03367
symbol: ssuD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the desulfonation of aliphatic sulfonates. Belongs to the SsuD family.


ensembl_gene_id: GCA_001297775_03369
symbol: ssuB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.


ensembl_gene_id: GCA_001297775_03371
symbol: pncB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.


ensembl_gene_id: GCA_001297775_03378
symbol: mukB
gene_biotype: protein_coding
description:
  Unannotated protein; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily.


ensembl_gene_id: GCA_001297775_03379
symbol: mukE
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.


ensembl_gene_id: GCA_001297775_03380
symbol: mukF
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.


ensembl_gene_id: GCA_001297775_03381
symbol: cmoM
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.


ensembl_gene_id: GCA_001297775_03384
symbol: kdsB
gene_biotype: protein_coding
description:
  Unannotated protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.


ensembl_gene_id: GCA_001297775_03387
symbol: lpxK
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).


ensembl_gene_id: GCA_001297775_03388
symbol: msbA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.


ensembl_gene_id: GCA_001297775_03391
symbol: rpsA
gene_biotype: protein_coding
description:
  Unannotated protein; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.


ensembl_gene_id: GCA_001297775_03394
symbol: aroA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.


ensembl_gene_id: GCA_001297775_03395
symbol: serC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.


ensembl_gene_id: GCA_001297775_03400
symbol: pflA
gene_biotype: protein_coding
description:
  Unannotated protein; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.


ensembl_gene_id: GCA_001297775_03402
symbol: serS
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).


ensembl_gene_id: GCA_001297775_03404
symbol: lolA
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).


ensembl_gene_id: GCA_001297775_03410
symbol: aat
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.


ensembl_gene_id: GCA_001297775_03411
symbol: infA
gene_biotype: protein_coding
description:
  Unannotated protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.


ensembl_gene_id: GCA_001297775_03413
symbol: clpS
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.


ensembl_gene_id: GCA_001297775_03415
symbol: macB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.


ensembl_gene_id: GCA_001297775_03418
symbol: aqpZ
gene_biotype: protein_coding
description:
  Unannotated protein; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.


ensembl_gene_id: GCA_001297775_03448
symbol: dld
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.


ensembl_gene_id: GCA_001297775_03452
symbol: dusC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily.


ensembl_gene_id: GCA_001297775_03455
symbol: cdd
gene_biotype: protein_coding
description:
  Unannotated protein; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.


ensembl_gene_id: GCA_001297775_03469
symbol: nfo
gene_biotype: protein_coding
description:
  Unannotated protein; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.


ensembl_gene_id: GCA_001297775_03489
symbol: lpxT
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.


ensembl_gene_id: GCA_001297775_03502
symbol: rplY
gene_biotype: protein_coding
description:
  Unannotated protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family.


ensembl_gene_id: GCA_001297775_03509
symbol: eco
gene_biotype: protein_coding
description:
  Unannotated protein; General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.


ensembl_gene_id: GCA_001297775_03516
symbol: GM31_17745
gene_biotype: protein_coding
description:
  Unannotated protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.


ensembl_gene_id: GCA_001297775_03518
symbol: rcsD
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.


ensembl_gene_id: GCA_001297775_03519
symbol: rcsB
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.


ensembl_gene_id: GCA_001297775_03520
symbol: rcsC
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.


ensembl_gene_id: GCA_001297775_03522
symbol: ubiG
gene_biotype: protein_coding
description:
  Unannotated protein; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.


ensembl_gene_id: GCA_001297775_03529
symbol: glpB
gene_biotype: protein_coding
description:
  Unannotated protein; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.


ensembl_gene_id: GCA_001297775_03533
symbol: rhmD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy- L-rhamnonate (KDR).


ensembl_gene_id: GCA_001297775_03540
symbol: menB
gene_biotype: protein_coding
description:
  Unannotated protein; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).


ensembl_gene_id: GCA_001297775_03541
symbol: menH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).


ensembl_gene_id: GCA_001297775_03542
symbol: menD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.


ensembl_gene_id: GCA_001297775_03546
symbol: rbn
gene_biotype: protein_coding
description:
  Unannotated protein; Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.


ensembl_gene_id: GCA_001297775_03551
symbol: nuoK
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.


ensembl_gene_id: GCA_001297775_03552
symbol: GM31_13230
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: GCA_001297775_03553
symbol: nuoI
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.


ensembl_gene_id: GCA_001297775_03554
symbol: nuoH
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.


ensembl_gene_id: GCA_001297775_03555
symbol: GM31_13215
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.


ensembl_gene_id: GCA_001297775_03556
symbol: GM31_13210
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.


ensembl_gene_id: GCA_001297775_03558
symbol: nuoC
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.


ensembl_gene_id: GCA_001297775_03560
symbol: nuoA
gene_biotype: protein_coding
description:
  Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.


ensembl_gene_id: GCA_001297775_03563
symbol: GM31_13170
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.


ensembl_gene_id: GCA_001297775_03568
symbol: ackA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.


ensembl_gene_id: GCA_001297775_03569
symbol: GM31_13140
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.


ensembl_gene_id: GCA_001297775_03589
symbol: ubiX
gene_biotype: protein_coding
description:
  Unannotated protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.


ensembl_gene_id: GCA_001297775_03590
symbol: purF
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.


ensembl_gene_id: GCA_001297775_03592
symbol: dedD
gene_biotype: protein_coding
description:
  Unannotated protein; Non-essential cell division protein that could be required for efficient cell constriction.


ensembl_gene_id: GCA_001297775_03593
symbol: GM31_13015
gene_biotype: protein_coding
description:
  Unannotated protein; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10- formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.


ensembl_gene_id: GCA_001297775_03594
symbol: accD
gene_biotype: protein_coding
description:
  Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.


ensembl_gene_id: GCA_001297775_03596
symbol: truA
gene_biotype: protein_coding
description:
  Unannotated protein; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.


ensembl_gene_id: GCA_001297775_03598
symbol: pdxB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.


ensembl_gene_id: GCA_001297775_03599
symbol: flk
gene_biotype: protein_coding
description:
  Unannotated protein; Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor FlgM upon sensing ring completion or hook elongation. Flk could inhibit FlgM secretion by acting as a braking system for the flagellar-associated type III secretion system.


ensembl_gene_id: GCA_001297775_03603
symbol: mnmC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family.


ensembl_gene_id: GCA_001297775_03612
symbol: mepA
gene_biotype: protein_coding
description:
  Unannotated protein; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family.


ensembl_gene_id: GCA_001297775_03613
symbol: aroC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.


ensembl_gene_id: GCA_001297775_03614
symbol: prmB
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.


ensembl_gene_id: GCA_001297775_03617
symbol: fadJ
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.


ensembl_gene_id: GCA_001297775_03641
symbol: GM31_20960
gene_biotype: protein_coding
description:
  Unannotated protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.


ensembl_gene_id: GCA_001297775_03658
symbol: mpl
gene_biotype: protein_coding
description:
  Unannotated protein; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.


ensembl_gene_id: GCA_001297775_03665
symbol: ppa
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.


ensembl_gene_id: GCA_001297775_03671
symbol: msrA
gene_biotype: protein_coding
description:
  Unannotated protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.


ensembl_gene_id: GCA_001297775_03682
symbol: cysQ
gene_biotype: protein_coding
description:
  Unannotated protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.


ensembl_gene_id: GCA_001297775_03688
symbol: ytfE
gene_biotype: protein_coding
description:
  Unannotated protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.


ensembl_gene_id: GCA_001297775_03693
symbol: rpsR
gene_biotype: protein_coding
description:
  Unannotated protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.


ensembl_gene_id: GCA_001297775_03694
symbol: priB
gene_biotype: protein_coding
description:
  Unannotated protein; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.


ensembl_gene_id: GCA_001297775_03716
symbol: rnr
gene_biotype: protein_coding
description:
  Unannotated protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily.


ensembl_gene_id: GCA_001297775_03717
symbol: nsrR
gene_biotype: protein_coding
description:
  Unannotated protein; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.


ensembl_gene_id: GCA_001297775_03718
symbol: purA
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.


ensembl_gene_id: GCA_001297775_03722
symbol: hflX
gene_biotype: protein_coding
description:
  Unannotated protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.


ensembl_gene_id: GCA_001297775_03723
symbol: hfq
gene_biotype: protein_coding
description:
  Unannotated protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.


ensembl_gene_id: GCA_001297775_03724
symbol: miaA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.


ensembl_gene_id: GCA_001297775_03725
symbol: mutL
gene_biotype: protein_coding
description:
  Unannotated protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.


ensembl_gene_id: GCA_001297775_03728
symbol: nnrD
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]


ensembl_gene_id: GCA_001297775_03729
symbol: queG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.


ensembl_gene_id: GCA_001297775_03733
symbol: orn
gene_biotype: protein_coding
description:
  Unannotated protein; 3'-to-5' exoribonuclease specific for small oligoribonucleotides; Belongs to the oligoribonuclease family.


ensembl_gene_id: GCA_001297775_03734
symbol: rsgA
gene_biotype: protein_coding
description:
  Unannotated protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.


ensembl_gene_id: GCA_001297775_03735
symbol: psd
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).


ensembl_gene_id: GCA_001297775_03737
symbol: epmA
gene_biotype: protein_coding
description:
  Unannotated protein; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.


ensembl_gene_id: GCA_001297775_03739
symbol: GM31_20205
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.


ensembl_gene_id: GCA_001297775_03740
symbol: frdC
gene_biotype: protein_coding
description:
  Unannotated protein; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane.


ensembl_gene_id: GCA_001297775_03742
symbol: GM31_20220
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.


ensembl_gene_id: GCA_001297775_03745
symbol: efp
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family.


ensembl_gene_id: GCA_001297775_03749
symbol: groEL
gene_biotype: protein_coding
description:
  Unannotated protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.


ensembl_gene_id: GCA_001297775_03750
symbol: groES
gene_biotype: protein_coding
description:
  Unannotated protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.


ensembl_gene_id: GCA_001297775_03756
symbol: dipZ
gene_biotype: protein_coding
description:
  Unannotated protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.


ensembl_gene_id: GCA_001297775_03792
symbol: cbpA
gene_biotype: protein_coding
description:
  Unannotated protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.


ensembl_gene_id: GCA_001297775_03806
symbol: GM31_01180
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. Belongs to the PhnJ family.


ensembl_gene_id: GCA_001297775_03810
symbol: phnN
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).


ensembl_gene_id: GCA_001297775_03817
symbol: gltP
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the proton-dependent transport of glutamate and aspartate; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily.


ensembl_gene_id: GCA_001297775_03818
symbol: acs
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.


ensembl_gene_id: GCA_001297775_03820
symbol: actP
gene_biotype: protein_coding
description:
  Unannotated protein; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.


ensembl_gene_id: GCA_001297775_03824
symbol: GM31_01095
gene_biotype: protein_coding
description:
  Unannotated protein; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.


ensembl_gene_id: GCA_001297775_03831
symbol: GM31_01050
gene_biotype: protein_coding
description:
  Unannotated protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.


ensembl_gene_id: GCA_001297775_03832
symbol: uvrA
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.


ensembl_gene_id: GCA_001297775_03839
symbol: GM31_01010
gene_biotype: protein_coding
description:
  Unannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.


ensembl_gene_id: GCA_001297775_03842
symbol: dusA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.


ensembl_gene_id: GCA_001297775_03847
symbol: lexA
gene_biotype: protein_coding
description:
  Unannotated protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.


ensembl_gene_id: GCA_001297775_03848
symbol: GM31_00965
gene_biotype: protein_coding
description:
  Unannotated protein; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.


ensembl_gene_id: GCA_001297775_03850
symbol: ubiA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.


ensembl_gene_id: GCA_001297775_03851
symbol: ubiC
gene_biotype: protein_coding
description:
  Unannotated protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.


ensembl_gene_id: GCA_001297775_03853
symbol: lamB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family.


ensembl_gene_id: GCA_001297775_03854
symbol: malK
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.


ensembl_gene_id: GCA_001297775_03855
symbol: malE
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family.


ensembl_gene_id: GCA_001297775_03871
symbol: metH
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.


ensembl_gene_id: GCA_001297775_03876
symbol: aceK
gene_biotype: protein_coding
description:
  Unannotated protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.


ensembl_gene_id: GCA_001297775_03879
symbol: metAS
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.


ensembl_gene_id: GCA_001297775_03900
symbol: GM31_22300
gene_biotype: protein_coding
description:
  Unannotated protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.


ensembl_gene_id: GCA_001297775_03906
symbol: betA
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.


ensembl_gene_id: GCA_001297775_03907
symbol: betB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.


ensembl_gene_id: GCA_001297775_03941
symbol: GM31_21205
gene_biotype: protein_coding
description:
  Unannotated protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.


ensembl_gene_id: GCA_001297775_03950
symbol: pagP
gene_biotype: protein_coding
description:
  Unannotated protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.


ensembl_gene_id: GCA_001297775_03952
symbol: crcB
gene_biotype: protein_coding
description:
  Unannotated protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.


ensembl_gene_id: GCA_001297775_03954
symbol: tatE
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily.


ensembl_gene_id: GCA_001297775_03955
symbol: lipA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.


ensembl_gene_id: GCA_001297775_03957
symbol: lipB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.


ensembl_gene_id: GCA_001297775_03960
symbol: rlpA
gene_biotype: protein_coding
description:
  Unannotated protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.


ensembl_gene_id: GCA_001297775_03961
symbol: mrdB
gene_biotype: protein_coding
description:
  Unannotated protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.


ensembl_gene_id: GCA_001297775_03962
symbol: mrdA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.


ensembl_gene_id: GCA_001297775_03963
symbol: rlmH
gene_biotype: protein_coding
description:
  Unannotated protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.


ensembl_gene_id: GCA_001297775_03964
symbol: rsfS
gene_biotype: protein_coding
description:
  Unannotated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.


ensembl_gene_id: GCA_001297775_03966
symbol: nadD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).


ensembl_gene_id: GCA_001297775_03968
symbol: lptE
gene_biotype: protein_coding
description:
  Unannotated protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.


ensembl_gene_id: GCA_001297775_03976
symbol: lnt
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily.


ensembl_gene_id: GCA_001297775_03978
symbol: ybeY
gene_biotype: protein_coding
description:
  Unannotated protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.


ensembl_gene_id: GCA_001297775_03980
symbol: miaB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.


ensembl_gene_id: GCA_001297775_03994
symbol: nagB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.


ensembl_gene_id: GCA_001297775_04003
symbol: seqA
gene_biotype: protein_coding
description:
  Unannotated protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.


ensembl_gene_id: GCA_001297775_04005
symbol: potE
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.


ensembl_gene_id: GCA_001297775_04009
symbol: kdpC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.


ensembl_gene_id: GCA_001297775_04010
symbol: kdpB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.


ensembl_gene_id: GCA_001297775_04011
symbol: kdpA
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.


ensembl_gene_id: GCA_001297775_04018
symbol: pxpA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.


ensembl_gene_id: GCA_001297775_04025
symbol: GM31_13580
gene_biotype: protein_coding
description:
  Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).


ensembl_gene_id: GCA_001297775_04026
symbol: sucC
gene_biotype: protein_coding
description:
  Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.


ensembl_gene_id: GCA_001297775_04027
symbol: sucD
gene_biotype: protein_coding
description:
  Unannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.


ensembl_gene_id: GCA_001297775_04034
symbol: tolQ
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: GCA_001297775_04035
symbol: tolR
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.


ensembl_gene_id: GCA_001297775_04037
symbol: tolB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.


ensembl_gene_id: GCA_001297775_04038
symbol: pal
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.


ensembl_gene_id: GCA_001297775_04039
symbol: cpoB
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.


ensembl_gene_id: GCA_001297775_04045
symbol: nadA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily.


ensembl_gene_id: GCA_001297775_04050
symbol: gpmA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.


ensembl_gene_id: GCA_001297775_04052
symbol: galK
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.


ensembl_gene_id: GCA_001297775_04057
symbol: acrZ
gene_biotype: protein_coding
description:
  Unannotated protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.


ensembl_gene_id: GCA_001297775_04059
symbol: modB
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.


ensembl_gene_id: GCA_001297775_04060
symbol: modC
gene_biotype: protein_coding
description:
  Unannotated protein; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.


ensembl_gene_id: GCA_001297775_04065
symbol: hutG
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.


ensembl_gene_id: GCA_001297775_04071
symbol: bioA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.


ensembl_gene_id: GCA_001297775_04072
symbol: bioB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.


ensembl_gene_id: GCA_001297775_04074
symbol: bioC
gene_biotype: protein_coding
description:
  Unannotated protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.


ensembl_gene_id: GCA_001297775_04075
symbol: bioD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family.


ensembl_gene_id: GCA_001297775_04076
symbol: uvrB
gene_biotype: protein_coding
description:
  Unannotated protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the [...]


ensembl_gene_id: GCA_001297775_04081
symbol: GM31_00060
gene_biotype: protein_coding
description:
  Unannotated protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.


ensembl_gene_id: GCA_001297775_04082
symbol: moaA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.


ensembl_gene_id: GCA_001297775_04083
symbol: GM31_00070
gene_biotype: protein_coding
description:
  Unannotated protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.


ensembl_gene_id: GCA_001297775_04084
symbol: moaC
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.


ensembl_gene_id: GCA_001297775_04089
symbol: clsB
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.


ensembl_gene_id: GCA_001297775_04097
symbol: rhlE
gene_biotype: protein_coding
description:
  Unannotated protein; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.


ensembl_gene_id: GCA_001297775_04109
symbol: dps
gene_biotype: protein_coding
description:
  Unannotated protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Belongs to the Dps family.


ensembl_gene_id: GCA_001297775_04123
symbol: tpx
gene_biotype: protein_coding
description:
  Unannotated protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.


ensembl_gene_id: GCA_001297775_04131
symbol: zntB
gene_biotype: protein_coding
description:
  Unannotated protein; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.


ensembl_gene_id: GCA_001297775_04134
symbol: ttcA
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.


ensembl_gene_id: GCA_001297775_04159
symbol: GM31_00395
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).


ensembl_gene_id: GCA_001297775_04163
symbol: azoR
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.


ensembl_gene_id: GCA_001297775_04173
symbol: GM31_00320
gene_biotype: protein_coding
description:
  Unannotated protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.


ensembl_gene_id: GCA_001297775_04181
symbol: mdoD
gene_biotype: protein_coding
description:
  Unannotated protein; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs). Belongs to the OpgD/OpgG family.


ensembl_gene_id: GCA_001297775_04202
symbol: patD
gene_biotype: protein_coding
description:
  Unannotated protein; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.


ensembl_gene_id: GCA_001297775_04254
symbol: sotB
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites; Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.


ensembl_gene_id: GCA_001297775_04280
symbol: GM31_04620
gene_biotype: protein_coding
description:
  Unannotated protein; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.


ensembl_gene_id: GCA_001297775_04302
symbol: GM31_17855
gene_biotype: protein_coding
description:
  Unannotated protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.


ensembl_gene_id: GCA_001297775_04307
symbol: pntB
gene_biotype: protein_coding
description:
  Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.


ensembl_gene_id: GCA_001297775_04308
symbol: pntA
gene_biotype: protein_coding
description:
  Unannotated protein; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.


